Lista de obras -

8-Thioalkyl-adenosine derivatives inhibit Listeria monocytogenes NAD kinase through a novel binding mode.

artículo científico publicado en 2016

@TOME-2: a new pipeline for comparative modeling of protein-ligand complexes.

artículo científico publicado en 2009

A 20-amino acid module of protein kinase C{epsilon} involved in translocation and selective targeting at cell-cell contacts

scientific journal article

A Tiny Change Makes a Big Difference in the Anti-Parasitic Activities of an HDAC Inhibitor

scientific article published on 18 June 2019

A new autosomal dominant eye and lung syndrome linked to mutations in TIMP3 gene.

artículo científico publicado en 2016

A phospho-sugar binding domain homologous to NagB enzymes regulates the activity of the central glycolytic genes repressor.

artículo científico publicado en 2008

Automat and BLAST: comparison of two protein sequence similarity search programs.

artículo científico publicado en 1995

CMP kinase from Escherichia coli is structurally related to other nucleoside monophosphate kinases.

artículo científico publicado en 1996

Characterization and overexpression of the pem gene encoding pectin methylesterase of Erwinia chrysanthemi strain 3937.

artículo científico publicado en 1993

Characterization of XPR1/SLC53A1 variants located outside of the SPX domain in patients with primary familial brain calcification

artículo científico publicado en 2019

Chromatin Insulator Factors Involved in Long-Range DNA Interactions and Their Role in the Folding of the Drosophila Genome

artículo científico publicado en 2014

Combining 'dry' co-crystallization and in situ diffraction to facilitate ligand screening by X-ray crystallography

artículo científico publicado en 2015

Comparative modelling and immunochemical reactivity of Escherichia coli UMP kinase.

artículo científico publicado en 2002

Comparative sequence analysis and predictions for the envelope glycoproteins of insect endogenous retroviruses.

artículo científico publicado en 2003

Comprehensive 3D-modeling of allergenic proteins and amino acid composition of potential conformational IgE epitopes.

artículo científico publicado en 2008

Comprehensive classification of the plant non-specific lipid transfer protein superfamily towards its sequence-structure-function analysis

artículo científico publicado en 2019

Correction for Vigneron et al., "Characterization of the Mechanisms Controlling Greatwall Activity".

artículo científico publicado en 2017

Correction: N6-Substituted AMPs Inhibit Mammalian Deoxynucleotide N-Hydrolase DNPH1.

artículo científico publicado en 2014

Coupling of agonist binding to effector domain activation in metabotropic glutamate-like receptors

scientific article published on 20 June 2006

Crystallization and preliminary crystallographic studies of MOMP (major outer membrane protein) from Campylobacter jejuni.

artículo científico publicado en 2004

Crystallographic and spectroscopic studies of native, aminoquinol, and monovalent cation-bound forms of methylamine dehydrogenase from Methylobacterium extorquens AM1

scientific article published on 01 October 1998

Crystallographic studies of two variants of Pseudomonas aeruginosa IMPDH with impaired allosteric regulation

artículo científico publicado en 2015

Deciphering protein sequence information through hydrophobic cluster analysis (HCA): current status and perspectives.

artículo científico publicado en 1997

Design of Mycobacterium tuberculosis thymidine monophosphate kinase inhibitors.

artículo científico publicado en 2003

Diacylglyceride kinases, sphingosine kinases and NAD kinases: distant relatives of 6-phosphofructokinases.

artículo científico publicado en 2002

Dimerization of the Pragmin Pseudo-Kinase Regulates Protein Tyrosine Phosphorylation

artículo científico publicado en 2018

Dimerization of the Pragmin Pseudo-Kinase Regulates Protein Tyrosine Phosphorylation

artículo científico publicado en 2018

Engineering, expression and biochemical characterization of the hemoglobin domain of a Erwinia chrysanthemi flavohemoprotein.

artículo científico publicado en 1998

First-in-class allosteric inhibitors of bacterial IMPDHs

scientific article published on 02 February 2019

Fragment and conquer: from structure to complexes to function

scientific article published on 01 October 2012

Functioning of the dimeric GABA(B) receptor extracellular domain revealed by glycan wedge scanning.

artículo científico publicado en 2008

HAH1 is a copper-binding protein with distinct amino acid residues mediating copper homeostasis and antioxidant defense

artículo científico publicado en 1998

Homodimerization of RBPMS2 through a new RRM-interaction motif is necessary to control smooth muscle plasticity

artículo científico publicado en 2014

In Silico Predictions of Endocrine Disruptors Properties

artículo científico publicado en 2019

In-plate protein crystallization, in situ ligand soaking and X-ray diffraction

artículo científico publicado en 2011

Incremental threading optimization (TITO) to help alignment and modelling of remote homologues.

artículo científico publicado en 1998

Interdomain movements in metabotropic glutamate receptor activation ⬇️

artículo científico publicado el 6 de septiembre de 2011

Janus kinases and focal adhesion kinases play in the 4.1 band: a superfamily of band 4.1 domains important for cell structure and signal transduction

artículo científico publicado en 1998

LEA3D: a computer-aided ligand design for structure-based drug design.

artículo científico publicado en 2005

Lack of dynamics in the MabA active site kills the enzyme activity: practical consequences for drug-design studies

artículo científico publicado en 2007

MgATP regulates allostery and fiber formation in IMPDHs

artículo científico publicado en 2013

Molecular Dynamics Simulations of the Allosteric Modulation of the Adenosine A2A Receptor by a Mini-G Protein

artículo científico publicado en 2019

Molecular cloning and partial characterization of a plant VAP33 homologue with a major sperm protein domain.

artículo científico publicado en 2000

Molecular recognition of paxillin LD motifs by the focal adhesion targeting domain

artículo científico publicado en 2003

Montpellier infectious diseases (MID): 1st annual meeting (2011).

artículo científico publicado en 2011

MulBlast 1.0: a multiple alignment of BLAST output to boost protein sequence similarity analysis.

artículo científico publicado en 1996

Mutation at the "exit gate" of the salmonella gyrase a subunit suppresses a defect in the gyrase B subunit.

artículo científico publicado en 2005

Mutations in IMPG1 cause vitelliform macular dystrophies.

artículo científico publicado en 2013

N (6)-substituted AMPs inhibit mammalian deoxynucleotide N-hydrolase DNPH1

artículo científico publicado en 2013

NAD kinases use substrate-assisted catalysis for specific recognition of NAD

artículo científico publicado en 2007

New Chemical Probe Targeting Bacterial NAD Kinase

artículo científico publicado en 2020

No ligand binding in the GB2 subunit of the GABA(B) receptor is required for activation and allosteric interaction between the subunits.

artículo científico publicado en 2002

Nonclassical Ligand-Independent Regulation of Go Protein by an Orphan Class C G-Protein-Coupled Receptor

artículo científico publicado en 2019

Nucleoside analogues as inhibitors of thymidylate kinases: possible therapeutic applications.

artículo científico publicado en 2002

Oleoyl coenzyme A regulates interaction of transcriptional regulator RaaS (Rv1219c) with DNA in mycobacteria

artículo científico publicado en 2014

PROKR2 missense mutations associated with Kallmann syndrome impair receptor signalling activity

artículo científico publicado en 2009

Phosphodeoxyribosyltransferases, Designed Enzymes for Deoxyribonucleotides Synthesis

artículo científico publicado en 2013

Polyhydroxynaphthalene reductase involved in melanin biosynthesis in Magnaporthe grisea. Purification, cDNA cloning and sequencing.

artículo científico publicado en 1994

ROP2 from Toxoplasma gondii: a virulence factor with a protein-kinase fold and no enzymatic activity

artículo científico publicado en 2009

Resuscitation-promoting factors possess a lysozyme-like domain

artículo científico publicado en 2004

SHEDding light on the role of Pragmin pseudo-kinases in cancer

artículo científico publicado en 2019

Screening and in situ synthesis using crystals of a NAD kinase lead to a potent antistaphylococcal compound

artículo científico publicado en 2012

Structural and mechanistic insights into bisphenols action provide guidelines for risk assessment and discovery of bisphenol A substitutes

artículo científico publicado en 2012

Structural basis for chemically-induced homodimerization of a single domain antibody

artículo científico publicado en 2019

Structural characterization of the mammalian deoxynucleotide N-hydrolase Rcl and its stabilizing interactions with two inhibitors

artículo científico publicado en 2009

Structural comparisons lead to the definition of a new superfamily of NAD(P)(H)-accepting oxidoreductases: the single-domain reductases/epimerases/dehydrogenases (the 'RED' family).

artículo científico publicado en 1994

Structure of the oncoprotein Rcl bound to three nucleotide analogues

artículo científico publicado en 2013

Synthesis of aminophenylhydroxamate and aminobenzylhydroxamate derivatives and in vitro screening for antiparasitic and histone deacetylase inhibitory activity.

artículo científico publicado en 2018

The C-Terminal Domain of the Virulence Factor MgtC Is a Divergent ACT Domain

artículo científico publicado en 2012

The Drosophila Bruno paralogue Bru-3 specifically binds the EDEN translational repression element.

artículo científico publicado en 2004

The Leishmania nicotinamidase is essential for NAD+ production and parasite proliferation

artículo científico publicado en 2011

The endonuclease domain of bacteriophage terminases belongs to the resolvase/integrase/ribonuclease H superfamily: a bioinformatics analysis validated by a functional study on bacteriophage T5.

artículo científico publicado en 2005

The stoichiometry of scaffold complexes in living neurons - DLC2 functions as a dimerization engine for GKAP.

artículo científico publicado en 2014

The structure of PknB in complex with mitoxantrone, an ATP-competitive inhibitor, suggests a mode of protein kinase regulation in mycobacteria

artículo científico publicado en 2006

Thymidylate kinase of Mycobacterium tuberculosis: a chimera sharing properties common to eukaryotic and bacterial enzymes

artículo científico publicado en 2001

Towards accurate high-throughput ligand affinity prediction by exploiting structural ensembles, docking metrics and ligand similarity

artículo científico publicado en 2020

UMP kinase from the Gram-positive bacterium Bacillus subtilis is strongly dependent on GTP for optimal activity.

artículo científico publicado en 2003

ViTO: tool for refinement of protein sequence-structure alignments

artículo científico publicado en 2004

Lista de obras de

8-Thioalkyl-adenosine derivatives inhibit Listeria monocytogenes NAD kinase through a novel binding mode.

@TOME-2: a new pipeline for comparative modeling of protein-ligand complexes.

A 20-amino acid module of protein kinase C{epsilon} involved in translocation and selective targeting at cell-cell contacts

A Tiny Change Makes a Big Difference in the Anti-Parasitic Activities of an HDAC Inhibitor

A new autosomal dominant eye and lung syndrome linked to mutations in TIMP3 gene.

A phospho-sugar binding domain homologous to NagB enzymes regulates the activity of the central glycolytic genes repressor.

Automat and BLAST: comparison of two protein sequence similarity search programs.

CMP kinase from Escherichia coli is structurally related to other nucleoside monophosphate kinases.

Characterization and overexpression of the pem gene encoding pectin methylesterase of Erwinia chrysanthemi strain 3937.

Characterization of XPR1/SLC53A1 variants located outside of the SPX domain in patients with primary familial brain calcification

Chromatin Insulator Factors Involved in Long-Range DNA Interactions and Their Role in the Folding of the Drosophila Genome

Combining 'dry' co-crystallization and in situ diffraction to facilitate ligand screening by X-ray crystallography

Comparative modelling and immunochemical reactivity of Escherichia coli UMP kinase.

Comparative sequence analysis and predictions for the envelope glycoproteins of insect endogenous retroviruses.

Comprehensive 3D-modeling of allergenic proteins and amino acid composition of potential conformational IgE epitopes.

Comprehensive classification of the plant non-specific lipid transfer protein superfamily towards its sequence-structure-function analysis

Correction for Vigneron et al., "Characterization of the Mechanisms Controlling Greatwall Activity".

Correction: N6-Substituted AMPs Inhibit Mammalian Deoxynucleotide N-Hydrolase DNPH1.

Coupling of agonist binding to effector domain activation in metabotropic glutamate-like receptors

Crystallization and preliminary crystallographic studies of MOMP (major outer membrane protein) from Campylobacter jejuni.

Crystallographic and spectroscopic studies of native, aminoquinol, and monovalent cation-bound forms of methylamine dehydrogenase from Methylobacterium extorquens AM1

Crystallographic studies of two variants of Pseudomonas aeruginosa IMPDH with impaired allosteric regulation

Deciphering protein sequence information through hydrophobic cluster analysis (HCA): current status and perspectives.

Design of Mycobacterium tuberculosis thymidine monophosphate kinase inhibitors.

Diacylglyceride kinases, sphingosine kinases and NAD kinases: distant relatives of 6-phosphofructokinases.

Dimerization of the Pragmin Pseudo-Kinase Regulates Protein Tyrosine Phosphorylation

Dimerization of the Pragmin Pseudo-Kinase Regulates Protein Tyrosine Phosphorylation

Engineering, expression and biochemical characterization of the hemoglobin domain of a Erwinia chrysanthemi flavohemoprotein.

First-in-class allosteric inhibitors of bacterial IMPDHs

Fragment and conquer: from structure to complexes to function

Functioning of the dimeric GABA(B) receptor extracellular domain revealed by glycan wedge scanning.

HAH1 is a copper-binding protein with distinct amino acid residues mediating copper homeostasis and antioxidant defense

Homodimerization of RBPMS2 through a new RRM-interaction motif is necessary to control smooth muscle plasticity

In Silico Predictions of Endocrine Disruptors Properties

In-plate protein crystallization, in situ ligand soaking and X-ray diffraction

Incremental threading optimization (TITO) to help alignment and modelling of remote homologues.

Interdomain movements in metabotropic glutamate receptor activation ⬇️

Janus kinases and focal adhesion kinases play in the 4.1 band: a superfamily of band 4.1 domains important for cell structure and signal transduction

LEA3D: a computer-aided ligand design for structure-based drug design.

Lack of dynamics in the MabA active site kills the enzyme activity: practical consequences for drug-design studies

MgATP regulates allostery and fiber formation in IMPDHs

Molecular Dynamics Simulations of the Allosteric Modulation of the Adenosine A2A Receptor by a Mini-G Protein

Molecular cloning and partial characterization of a plant VAP33 homologue with a major sperm protein domain.

Molecular recognition of paxillin LD motifs by the focal adhesion targeting domain

Montpellier infectious diseases (MID): 1st annual meeting (2011).

MulBlast 1.0: a multiple alignment of BLAST output to boost protein sequence similarity analysis.

Mutation at the "exit gate" of the salmonella gyrase a subunit suppresses a defect in the gyrase B subunit.

Mutations in IMPG1 cause vitelliform macular dystrophies.

N (6)-substituted AMPs inhibit mammalian deoxynucleotide N-hydrolase DNPH1

NAD kinases use substrate-assisted catalysis for specific recognition of NAD

New Chemical Probe Targeting Bacterial NAD Kinase

No ligand binding in the GB2 subunit of the GABA(B) receptor is required for activation and allosteric interaction between the subunits.

Nonclassical Ligand-Independent Regulation of Go Protein by an Orphan Class C G-Protein-Coupled Receptor

Nucleoside analogues as inhibitors of thymidylate kinases: possible therapeutic applications.

Oleoyl coenzyme A regulates interaction of transcriptional regulator RaaS (Rv1219c) with DNA in mycobacteria

PROKR2 missense mutations associated with Kallmann syndrome impair receptor signalling activity

Phosphodeoxyribosyltransferases, Designed Enzymes for Deoxyribonucleotides Synthesis

Polyhydroxynaphthalene reductase involved in melanin biosynthesis in Magnaporthe grisea. Purification, cDNA cloning and sequencing.

ROP2 from Toxoplasma gondii: a virulence factor with a protein-kinase fold and no enzymatic activity

Resuscitation-promoting factors possess a lysozyme-like domain

SHEDding light on the role of Pragmin pseudo-kinases in cancer

Screening and in situ synthesis using crystals of a NAD kinase lead to a potent antistaphylococcal compound

Structural and mechanistic insights into bisphenols action provide guidelines for risk assessment and discovery of bisphenol A substitutes

Structural basis for chemically-induced homodimerization of a single domain antibody

Structural characterization of the mammalian deoxynucleotide N-hydrolase Rcl and its stabilizing interactions with two inhibitors

Structural comparisons lead to the definition of a new superfamily of NAD(P)(H)-accepting oxidoreductases: the single-domain reductases/epimerases/dehydrogenases (the 'RED' family).

Structure of the oncoprotein Rcl bound to three nucleotide analogues

Synthesis of aminophenylhydroxamate and aminobenzylhydroxamate derivatives and in vitro screening for antiparasitic and histone deacetylase inhibitory activity.

The C-Terminal Domain of the Virulence Factor MgtC Is a Divergent ACT Domain

The Drosophila Bruno paralogue Bru-3 specifically binds the EDEN translational repression element.

The Leishmania nicotinamidase is essential for NAD+ production and parasite proliferation

The endonuclease domain of bacteriophage terminases belongs to the resolvase/integrase/ribonuclease H superfamily: a bioinformatics analysis validated by a functional study on bacteriophage T5.

The stoichiometry of scaffold complexes in living neurons - DLC2 functions as a dimerization engine for GKAP.

The structure of PknB in complex with mitoxantrone, an ATP-competitive inhibitor, suggests a mode of protein kinase regulation in mycobacteria

Thymidylate kinase of Mycobacterium tuberculosis: a chimera sharing properties common to eukaryotic and bacterial enzymes

Towards accurate high-throughput ligand affinity prediction by exploiting structural ensembles, docking metrics and ligand similarity

UMP kinase from the Gram-positive bacterium Bacillus subtilis is strongly dependent on GTP for optimal activity.

ViTO: tool for refinement of protein sequence-structure alignments