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Adenosine A1 receptor activation modulates N-methyl-d-aspartate (NMDA) preconditioning phenotype in the brain.

artículo científico publicado en 2014

Adenosine A1 receptor-dependent antinociception induced by inosine in mice: pharmacological, genetic and biochemical aspects.

artículo científico

Adenosine A1-A2A Receptor-Receptor Interaction: Contribution to Guanosine-Mediated Effects

scientific article published on 13 December 2019

Adenosine and NMDA Receptors Modulate Neuroprotection-Induced NMDA Preconditioning in Mice

artículo científico publicado en 2019

Aloysia gratissima prevents cellular damage induced by glutamatergic excitotoxicity.

artículo científico publicado en 2014

Antidepressant-like and neuroprotective effects of Aloysia gratissima: investigation of involvement of L-arginine-nitric oxide-cyclic guanosine monophosphate pathway.

artículo científico publicado en 2011

Antiparkinsonian Efficacy of Guanosine in Rodent Models of Movement Disorder.

artículo científico publicado en 2017

Anxiogenic-like profile of Wistar adult rats based on the pilocarpine model: an animal model for trait anxiety?

artículo científico publicado en 2012

Atorvastatin Improves Mitochondrial Function and Prevents Oxidative Stress in Hippocampus Following Amyloid-β1-40 Intracerebroventricular Administration in Mice

artículo científico publicado en 2020

Atorvastatin Prevents Cognitive Deficits Induced by Intracerebroventricular Amyloid-β1-40 Administration in Mice: Involvement of Glutamatergic and Antioxidant Systems.

artículo científico publicado en 2015

Atorvastatin Prevents Early Oxidative Events and Modulates Inflammatory Mediators in the Striatum Following Intranasal 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) Administration in Rats.

artículo científico publicado en 2017

Atorvastatin Prevents Glutamate Uptake Reduction Induced by Quinolinic Acid Via MAPKs Signaling.

artículo científico publicado en 2016

Atorvastatin Promotes Cytotoxicity and Reduces Migration and Proliferation of Human A172 Glioma Cells.

artículo científico publicado en 2017

Atorvastatin Protects from Aβ1-40-Induced Cell Damage and Depressive-Like Behavior via ProBDNF Cleavage.

artículo científico publicado en 2016

Atorvastatin and Fluoxetine Prevent Oxidative Stress and Mitochondrial Dysfunction Evoked by Glutamate Toxicity in Hippocampal Slices

artículo científico publicado en 2016

Atorvastatin evokes a serotonergic system-dependent antidepressant-like effect in mice

artículo científico publicado en 2014

Atorvastatin improves cognitive, emotional and motor impairments induced by intranasal 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) administration in rats, an experimental model of Parkinson's disease

artículo científico publicado el 30 de marzo de 2013

Atorvastatin prevents cell damage via modulation of oxidative stress, glutamate uptake and glutamine synthetase activity in hippocampal slices subjected to oxygen/glucose deprivation

artículo científico publicado el 14 de marzo de 2013

Atorvastatin prevents hippocampal cell death due to quinolinic acid-induced seizures in mice by increasing Akt phosphorylation and glutamate uptake.

artículo científico publicado en 2009

Atorvastatin prevents hippocampal cell death, neuroinflammation and oxidative stress following amyloid-β1–40 administration in mice: Evidence for dissociation between cognitive deficits and neuronal damage

artículo científico publicado el 15 de septiembre de 2010

Battling Alzheimer's Disease: Targeting SUMOylation-Mediated Pathways

artículo científico

Cell signaling in NMDA preconditioning and neuroprotection in convulsions induced by quinolinic acid.

artículo científico publicado en 2011

Cerebral cortex, hippocampus, striatum and cerebellum show differential susceptibility to quinolinic acid-induced oxidative stress.

artículo científico publicado en 2015

Coadministration of cannabinoid CB1-receptor and adenosine A1-receptor antagonists improves the acquisition of spatial memory in mice: participation of glutamatergic neurotransmission

artículo científico publicado en 2012

ConBr, a lectin from Canavalia brasiliensis seeds, protects against quinolinic acid-induced seizures in mice.

artículo científico publicado en 2011

Creatine affords protection against glutamate-induced nitrosative and oxidative stress

artículo científico publicado en 2016

Deciphering G protein-coupled receptor biology with fluorescence-based methods

artículo científico

Effects of adenosine on cAMP production during early development in the optic tectum of chicks.

artículo científico

Evaluation of glutathione metabolism in NMDA preconditioning against quinolinic acid-induced seizures in mice cerebral cortex and hippocampus.

artículo científico publicado en 2007

Evidence of the involvement of the monoaminergic systems in the antidepressant-like effect of Aloysia gratissima.

artículo científico publicado en 2013

Ferulic acid exerts antidepressant-like effect in the tail suspension test in mice: Evidence for the involvement of the serotonergic system

artículo científico publicado en 2012

Fluorescence resonance energy transfer-based technologies in the study of protein-protein interactions at the cell surface

artículo científico

G protein-coupled receptor oligomerization and brain integration: focus on adenosinergic transmission.

artículo científico

Guanine derivatives modulate L-glutamate uptake into rat brain synaptic vesicles.

artículo científico publicado en 2004

Guanine derivatives modulate extracellular matrix proteins organization and improve neuron-astrocyte co-culture.

artículo científico publicado en 2007

Guanine nucleotides inhibit cAMP accumulation induced by metabotropic glutamate receptor activation.

artículo científico publicado en 1998

Guanine nucleotides inhibit the stimulation of GFAP phosphorylation by glutamate

scientific article published on 01 January 1995

Guanosine Neuroprotective Action in Hippocampal Slices Subjected to Oxygen and Glucose Deprivation Restores ATP Levels, Lactate Release and Glutamate Uptake Impairment: Involvement of Nitric Oxide

artículo científico publicado en 2020

Guanosine Prevents Anhedonic-Like Behavior and Impairment in Hippocampal Glutamate Transport Following Amyloid-β1-40 Administration in Mice

artículo científico publicado en 2016

Guanosine Promotes Proliferation in Neural Stem Cells from Hippocampus and Neurogenesis in Adult Mice

artículo científico publicado en 2020

Guanosine Protects Striatal Slices Against 6-OHDA-Induced Oxidative Damage, Mitochondrial Dysfunction, and ATP Depletion

artículo científico publicado en 2018

Guanosine and GMP increase the number of granular cerebellar neurons in culture: dependence on adenosine A2A and ionotropic glutamate receptors

scientific article published on 02 September 2019

Guanosine is neuroprotective against oxygen/glucose deprivation in hippocampal slices via large conductance Ca²+-activated K+ channels, phosphatidilinositol-3 kinase/protein kinase B pathway activation and glutamate uptake

scientific article published on 22 March 2011

Guanosine prevents depressive-like behaviors in rats following bilateral dorsolateral striatum lesion induced by 6-hydroxydopamine

scientific article published on 15 June 2019

Guanosine prevents nitroxidative stress and recovers mitochondrial membrane potential disruption in hippocampal slices subjected to oxygen/glucose deprivation.

artículo científico publicado en 2016

Guanosine prevents oxidative damage and glutamate uptake impairment induced by oxygen/glucose deprivation in cortical astrocyte cultures: involvement of A1 and A2A adenosine receptors and PI3K, MEK, and PKC pathways

artículo científico publicado en 2019

Guanosine promotes cytotoxicity via adenosine receptors and induces apoptosis in temozolomide-treated A172 glioma cells.

artículo científico publicado en 2017

Guanosine protects human neuroblastoma SH-SY5Y cells against mitochondrial oxidative stress by inducing heme oxigenase-1 via PI3K/Akt/GSK-3β pathway.

artículo científico publicado en 2012

Guanosine-5'-monophosphate induces cell death in rat hippocampal slices via ionotropic glutamate receptors activation and glutamate uptake inhibition.

artículo científico publicado en 2009

Guanosine: a Neuromodulator with Therapeutic Potential in Brain Disorders

artículo científico publicado en 2016

Impaired astrocytic extracellular matrix distribution under congenital hypothyroidism affects neuronal development in vitro

scientific article published on 01 November 2010

Impaired exercise capacity, but unaltered mitochondrial respiration in skeletal or cardiac muscle of mice lacking cellular prion protein.

artículo científico publicado en 2005

In vitro 6-hydroxydopamine-induced toxicity in striatal, cerebrocortical and hippocampal slices is attenuated by atorvastatin and MK-801.

artículo científico publicado en 2016

In vitro oxygen-glucose deprivation to study ischemic cell death.

artículo científico publicado en 2015

In vivo quinolinic acid increases synaptosomal glutamate release in rats: reversal by guanosine.

artículo científico publicado en 2005

Increased susceptibility to amyloid-β-induced neurotoxicity in mice lacking the low-density lipoprotein receptor

artículo científico publicado en 2014

Influence of environmental enrichment vs. time-of-day on behavioral repertoire of male albino Swiss mice.

artículo científico publicado en 2015

Inhibition of glutamate uptake into synaptic vesicles from rat brain by 3-nitropropionic acid in vitro.

artículo científico publicado en 2001

Inhibition of glutamate uptake into synaptic vesicles of rat brain by the metabolites accumulating in maple syrup urine disease

scientific article published on 01 December 2000

Inhibition of reductase systems by 2-AAPA modulates peroxiredoxin oxidation and mitochondrial function in A172 glioblastoma cells.

artículo científico publicado en 2017

Interaction of adenosine and guanine derivatives in the rat hippocampus: effects on cyclic AMP levels and on the binding of adenosine analogues and GMP

artículo científico publicado en 2000

Intranasal administration of sodium dimethyldithiocarbamate induces motor deficits and dopaminergic dysfunction in mice.

artículo científico publicado en 2018

Involvement of PI3K/Akt Signaling Pathway and Its Downstream Intracellular Targets in the Antidepressant-Like Effect of Creatine.

artículo científico publicado en 2015

Involvement of PI3K/Akt/GSK-3β and mTOR in the antidepressant-like effect of atorvastatin in mice.

artículo científico publicado en 2016

Involvement of adenosine A1 and A2A receptors on guanosine-mediated anti-tremor effects in reserpinized mice

scientific article published on 28 July 2020

Involvement of glutamatergic neurotransmission in the antidepressant-like effect of zinc in the chronic unpredictable stress model of depression.

artículo científico publicado en 2016

Lithium and valproate prevent olfactory discrimination and short-term memory impairments in the intranasal 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) rat model of Parkinson's disease.

artículo científico publicado en 2012

Long-Term Neurobehavioral Consequences of a Single Ketamine Neonatal Exposure in Rats: Effects on Cellular Viability and Glutamate Transport in Frontal Cortex and Hippocampus

artículo científico publicado en 2018

Mechanism of guanosine-induced neuroprotection in rat hippocampal slices submitted to oxygen-glucose deprivation

scientific article published on 01 August 2007

Mechanisms underlying the neurotoxicity induced by glyphosate-based herbicide in immature rat hippocampus: involvement of glutamate excitotoxicity.

artículo científico publicado en 2014

Modulation of adenosine-induced cAMP accumulation via metabotropic glutamate receptors in chick optic tectum

artículo científico publicado en 1995

N-methyl-D-aspartate preconditioning improves short-term motor deficits outcome after mild traumatic brain injury in mice.

artículo científico publicado en 2010

N-methyl-D-aspartate preconditioning prevents quinolinic acid-induced deregulation of glutamate and calcium homeostasis in mice hippocampus.

artículo científico publicado en 2014

NMDA preconditioning attenuates cortical and hippocampal seizures induced by intracerebroventricular quinolinic acid infusion.

artículo científico publicado en 2012

NMDA preconditioning protects against quinolinic acid-induced seizures via PKA, PI3K and MAPK/ERK signaling pathways.

artículo científico publicado en 2010

Neuromodulatory Effects of Guanine-Based Purines in Health and Disease

article

Neuroprotection Promoted by Guanosine Depends on Glutamine Synthetase and Glutamate Transporters Activity in Hippocampal Slices Subjected to Oxygen/Glucose Deprivation

artículo científico publicado en 2016

Neuroprotection induced by NMDA preconditioning as a strategy to understand brain tolerance mechanism.

artículo científico publicado en 2015

Neuroprotective effect of GMP in hippocampal slices submitted to an in vitro model of ischemia.

artículo científico publicado en 2002

Neurotoxicity induced by dexamethasone in the human neuroblastoma SH-SY5Y cell line can be prevented by folic acid.

artículo científico publicado en 2011

Neurotoxicity induced by glutamate in glucose-deprived rat hippocampal slices is prevented by GMP.

artículo científico publicado en 2005

New ionic targets of 3,3',5'-triiodothyronine at the plasma membrane of rat Sertoli cells

scientific article published on 09 January 2019

Normal brain mitochondrial respiration in adult mice lacking cellular prion protein.

artículo científico publicado en 2004

Novel synthetic chalcones induces apoptosis in human glioblastoma cells.

artículo científico publicado en 2016

Overexpression of cellular prion protein (PrP(C)) prevents cognitive dysfunction and apoptotic neuronal cell death induced by amyloid-β (Aβ₁₋₄₀) administration in mice.

artículo científico publicado en 2012

Oxygen-glucose deprivation decreases glutathione levels and glutamate uptake in rat hippocampal slices.

artículo científico publicado en 2006

Proteomic analysis of the mice hippocampus after preconditioning induced by N-methyl-D-aspartate (NMDA).

artículo científico publicado en 2012

Purine receptors are required for DHA-mediated neuroprotection against oxygen and glucose deprivation in hippocampal slices

artículo científico publicado en 2014

Q1VA, a Synthetic Chalcone, Induces Apoptosis and Decreases Invasion on Primary Culture of Human Glioblastoma

scientific article published in 2023

Quinolinic acid-induced seizures stimulate glutamate uptake into synaptic vesicles from rat brain: effects prevented by guanine-based purines

artículo científico publicado en 2007

Role of Phosphatidylinositol-3 Kinase Pathway in NMDA Preconditioning: Different Mechanisms for Seizures and Hippocampal Neuronal Degeneration Induced by Quinolinic Acid.

artículo científico publicado en 2018

Short bouts of mild-intensity physical exercise improve spatial learning and memory in aging rats: involvement of hippocampal plasticity via AKT, CREB and BDNF signaling.

artículo científico publicado en 2011

Statins enhance cognitive performance in object location test in albino Swiss mice: involvement of beta-adrenoceptors

artículo científico publicado en 2015

Synthetic organic compounds with potential for bacterial biofilm inhibition, a path for the identification of compounds interfering with quorum sensing.

artículo científico publicado en 2013

Targeting the guanine-based purinergic system in Alzheimer's disease.

artículo científico publicado en 2017

The Role of NMDA Receptors in the Development of Brain Resistance through Pre- and Postconditioning.

artículo científico

The modulation of NMDA receptors and L-arginine/nitric oxide pathway is implicated in the anti-immobility effect of creatine in the tail suspension test.

artículo científico publicado en 2015

Thyroid hormone increases astrocytic glutamate uptake and protects astrocytes and neurons against glutamate toxicity.

artículo científico publicado en 2008

Thyroid hormone mediates syndecan expression in rat neonatal cerebellum.

artículo científico publicado en 2008