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Alpha-bisabolol: unexpected plant-derived weapon in the struggle against tumour survival?

scientific article published on December 2007

Anti-interferon gamma action of epigallocatechin-3-gallate mediated by specific inhibition of STAT1 activation.

artículo científico publicado en 2001

Biochemical aspects of nitric oxide.

artículo científico publicado en 2004

Costunolide and Dehydrocostuslactone, two natural sesquiterpene lactones, ameliorate the inflammatory process associated to experimental pleurisy in mice

artículo científico publicado en 2014

Cross-Talk Between NO Synthase Isoforms in Neuro-Inflammation: Possible Implications in HIV-Associated Neurocognitive Disorders.

artículo científico publicado en 2016

Cross-talk between NO and arachidonic acid in inflammation.

artículo científico publicado en 2007

Direct interaction of natural and synthetic catechins with signal transducer activator of transcription 1 affects both its phosphorylation and activity.

artículo científico publicado en 2013

Dual cross-talk between nitric oxide and D-serine in astrocytes and neurons in the brain.

artículo científico publicado en 2009

Early nuclear factor-kappaB activation and inducible nitric oxide synthase expression in injured spinal cord neurons correlating with a diffuse reduction of constitutive nitric oxide synthase activity.

artículo científico publicado en 2006

Effect of a new non-steroidal anti-inflammatory drug, nitroflurbiprofen, on the expression of inducible nitric oxide synthase in rat neutrophils.

artículo científico publicado en 1995

Extracorporeal shock wave therapy in inflammatory diseases: molecular mechanism that triggers anti-inflammatory action.

artículo científico publicado en 2009

Flavanocoumarins from Guazuma ulmifolia bark and evaluation of their affinity for STAT1.

artículo científico publicado en 2012

Induction of nitric oxide synthase mRNA expression. Suppression by exogenous nitric oxide

scientific article published on 01 November 1995

Inhibition of inflammatory and proliferative responses of human keratinocytes exposed to the sesquiterpene lactones dehydrocostuslactone and costunolide.

artículo científico publicado en 2014

Intermolecular disulfide bond influences unphosphorylated STAT3 dimerization and function.

artículo científico publicado en 2016

Involvement of mitochondrial permeability transition pore opening in alpha-bisabolol induced apoptosis.

artículo científico publicado en 2009

Metastatic Breast Cancer Cells Enter Into Dormant State and Express Cancer Stem Cells Phenotype Under Chronic Hypoxia

artículo científico publicado en 2017

Mild oxidative stress induces S-glutathionylation of STAT3 and enhances chemosensitivity of tumoural cells to chemotherapeutic drugs

artículo científico publicado en 2013

Modulation of nitric oxide homeostasis in a mouse model of spinal cord injury

artículo científico publicado en 2006

Mutant p53 blocks SESN1/AMPK/PGC-1α/UCP2 axis increasing mitochondrial O· production in cancer cells

article

Mutant p53 proteins counteract autophagic mechanism sensitizing cancer cells to mTOR inhibition.

artículo científico publicado en 2016

Natural Sesquiterpene Lactones Enhance Chemosensitivity of Tumor Cells through Redox Regulation of STAT3 Signaling

artículo científico publicado en 2019

Pivotal role of arachidonic acid in the regulation of neuronal nitric oxide synthase activity and inducible nitric oxide synthase expression in activated astrocytes.

artículo científico publicado en 2008

Protective effect of Arbutus unedo aqueous extract in carrageenan-induced lung inflammation in mice

artículo científico publicado en 2007

Protective effect of NO on gastric lesions and inhibition of expression of gastric inducible NOS by flurbiprofen and its nitro-derivative, nitroflurbiprofen

artículo científico publicado en 1995

Protective effect of epigallocatechin-3-gallate on ischemia/reperfusion-induced injuries in the heart: STAT1 silencing flavonoid.

artículo científico publicado en 2007

Rapid inactivation of NOS-I by lipopolysaccharide plus interferon-gamma-induced tyrosine phosphorylation.

artículo científico publicado en 1999

S-Glutathionylation at Cys328 and Cys542 impairs STAT3 phosphorylation.

artículo científico publicado en 2014

S-glutathionylation exerts opposing roles in the regulation of STAT1 and STAT3 signaling in reactive microglia

artículo científico publicado en 2018

Targeting STAT1 by myricetin and delphinidin provides efficient protection of the heart from ischemia/reperfusion-induced injury.

artículo científico publicado en 2008

Two naturally occurring terpenes, dehydrocostuslactone and costunolide, decrease intracellular GSH content and inhibit STAT3 activation.

artículo científico publicado en 2011

Use of STAT1 inhibitors in the treatment of brain I/R injury and neurodegenerative diseases.

artículo científico publicado en 2011