Lista de obras - Etienne Chatelut - Dominio Público Uruguay

A Phase I, Dose-Escalation Trial of Pazopanib in Combination with Cisplatin in Patients with Advanced Solid Tumors: A UNICANCER Study.

artículo científico publicado en 2016

A limited sampling strategy for determining carboplatin AUC and monitoring drug dosage.

artículo científico publicado en 2000

A limited-sampling method for evaluation of the area under the curve of ultrafilterable carboplatin in children

scientific article published on 01 January 1998

A limited-sampling strategy for estimation of etoposide pharmacokinetics in cancer patients.

artículo científico publicado en 1999

A pharmacologically guided phase I study of carboplatin in combination with methotrexate and vinblastine in advanced urothelial cancer.

artículo científico publicado en 1995

A phase I dose-escalating and pharmacokinetic study of docetaxel and vinorelbine as first-line chemotherapy for metastatic breast cancer.

artículo científico publicado en 2007

A universal formula based on cystatin C to perform individual dosing of carboplatin in normal weight, underweight, and obese patients.

artículo científico publicado en 2009

An UPLC-MS/MS method for separation and accurate quantification of tamoxifen and its metabolites isomers

artículo científico publicado en 2014

Antiretroviral unbound concentration during pregnancy: piece of interest in the puzzle?

artículo científico publicado en 2017

Application of hematological toxicity modeling in clinical development of abexinostat (S-78454, PCI-24781), a new histone deacetylase inhibitor.

artículo científico publicado en 2013

Cellular pharmacokinetics of doxorubicin in patients with chronic lymphocytic leukemia: comparison of bolus administration and continuous infusion

scientific article published on 01 January 1993

Cerebrospinal fluid concentrations of carboplatin in a patient without blood-brain barrier disruption

artículo científico publicado en 1995

Cetuximab pharmacokinetic/pharmacodynamics relationships in advanced head and neck carcinoma patients

artículo científico publicado en 2019

Characterization of CPT-11 converting carboxylesterase activity in colon tumor and normal tissues: comparison with p-nitro-phenylacetate converting carboxylesterase activity

scientific article published on 01 July 2000

Circulating oxysterol metabolites as potential new surrogate markers in patients with hormone receptor-positive breast cancer: Results of the OXYTAM study.

artículo científico publicado en 2016

Clinical Pharmacokinetics and Pharmacodynamics of Dabrafenib

artículo científico publicado en 2019

Co-variables influencing 5-fluorouracil clearance during continuous venous infusion. A NONMEM analysis.

artículo científico publicado en 1998

Comparison of nonlinear mixed-effect and non-parametric expectation maximisation modelling for Bayesian estimation of carboplatin clearance in children.

artículo científico publicado en 2001

Comparison of the pharmacokinetics and efficacy of irinotecan after administration by the intravenous versus intraperitoneal route in mice

scientific article published on 01 January 1998

Continuous Infusion of Cilengitide Plus Chemoradiotherapy for Patients With Stage III Non-Small-cell Lung Cancer: A Phase I Study.

artículo científico publicado en 2017

Contribution of the MDRD equation and of cystatin C for renal function estimates in cancer patients.

artículo científico publicado en 2006

Correlation between Bevacizumab Exposure and Survival does not necessarily imply Causality. Letter to the Editor

artículo científico publicado en 2020

Determination of dolutegravir's unbound fraction in human plasma using validated equilibrium dialysis and LC-MS/MS methods

artículo científico publicado en 2017

Determination of plasma unbound fraction of voriconazole in patients treated with a prophylactic or a curative treatment

artículo científico publicado en 2014

Determination of unbound fraction of imatinib and N-desmethyl imatinib, validation of an UPLC-MS/MS assay and ultrafiltration method

artículo científico publicado en 2012

Determination of unbound fraction of pazopanib in vitro and in cancer patients reveals albumin as the main binding site

artículo científico publicado en 2015

Development and validation of an UHPLC-MS/MS method for simultaneous quantification of ibrutinib and its dihydrodiol-metabolite in human cerebrospinal fluid

artículo científico publicado en 2018

Dexamethasone as a probe for CYP3A4 metabolism: evidence of gender effect

scientific article published on 24 November 2006

Dexamethasone as a probe for docetaxel clearance.

artículo científico publicado en 2004

Dihydropyrimidine dehydrogenase activity in normal, inflammatory and tumour tissues of colon and liver in humans

artículo científico publicado en 2000

Diversity of dose-individualization and therapeutic drug monitoring practices of platinum compounds: a review

artículo científico publicado en 2020

Dose and time dependencies of 5-fluorouracil pharmacokinetics

scientific article published on 01 September 2000

Dose banding as an alternative to body surface area-based dosing of chemotherapeutic agents

artículo científico publicado en 2012

Efavirenz and Lopinavir Levels in HIV-Infected Women and Their Nursing Infants, in Mali

artículo científico publicado en 2018

Escalating dose of mitoxantrone with high-dose cyclophosphamide, carmustine, and etoposide in patients with refractory lymphoma undergoing autologous bone marrow transplantation

artículo científico publicado en 1994

Evaluation of a peptide ELISA for the detection of rituximab in serum.

artículo científico publicado en 2007

Evaluation of the Interaction of Amino Acid Infusion on 177Lu-Dotatate Pharmacokinetics in Patients with Gastroenteropancreatic Neuroendocrine Tumors

artículo científico publicado en 2019

Extended CSF cytarabine exposure following intrathecal administration of DTC 101.

artículo científico publicado en 1993

Factors accelerating liver fibrosis progression in renal transplant patients receiving ribavirin monotherapy for chronic hepatitis C.

artículo científico publicado en 2005

Factors affecting pharmacokinetic variability of oral topotecan: a population analysis

artículo científico publicado en 2004

GFR is better estimated by considering both serum cystatin C and creatinine levels.

artículo científico publicado en 2006

Genotyping of a family with a novel deleterious DPYD mutation supports the pretherapeutic screening of DPD deficiency with dihydrouracil/uracil ratio.

artículo científico publicado en 2015

High Resectability Rate of Initially Unresectable Colorectal Liver Metastases After UGT1A1-Adapted High-Dose Irinotecan Combined with LV5FU2 and Cetuximab: A Multicenter Phase II Study (ERBIFORT)

artículo científico publicado en 2016

How can we best monitor 5-FU administration to maximize benefit to risk ratio?

scientific article published on 23 November 2018

How to predict carboplatin clearance from standard morphological and biological characteristics in obese patients.

artículo científico publicado en 1997

Impact of the biochemical assay for serum creatinine measurement on the individual carboplatin dosing ⬇️

artículo científico publicado el 1 de enero de 2002

Individual dosing of carboplatin based on drug monitoring in children receiving high-dose chemotherapy.

artículo científico publicado en 2003

Influence of HCV genotype 1 subtypes on the virus response to PEG interferon alpha‐2a plus ribavirin therapy ⬇️

artículo científico publicado el 1 de marzo de 2011

Influence of methotrexate exposure on outcome in patients treated with MBVP chemotherapy for primary central nervous system lymphoma

artículo científico publicado en 2010

Inhibition of OCT2, MATE1 and MATE2-K as a possible mechanism of drug interaction between pazopanib and cisplatin

artículo científico publicado en 2016

Innovative Therapies for Children with Cancer pediatric phase I study of erlotinib in brainstem glioma and relapsing/refractory brain tumors

artículo científico publicado en 2010

Interest of cystatin C for individual dosing of anticancer drugs cleared by the kidneys

artículo científico publicado en 2007

International Society of Geriatric Oncology Chemotherapy Taskforce: evaluation of chemotherapy in older patients--an analysis of the medical literature.

artículo científico publicado en 2007

Intraindividual Pharmacokinetic Variability: Focus on Small-Molecule Kinase Inhibitors.

artículo científico publicado en 2017

Investigating the potential impact of dose banding for systemic anti-cancer therapy in the paediatric setting based on pharmacokinetic evidence.

artículo científico publicado en 2018

Irreversible hepatotoxicity after administration of trabectedin to a pleiomorphic sarcoma patient with a rare ABCC2 polymorphism: a case report.

artículo científico publicado en 2013

Is the unbound concentration of atazanavir of interest in therapeutic drug monitoring?

artículo científico publicado en 2016

Life-threatening complications after high-dose methotrexate and the benefits of glucarpidase as salvage therapy: a cohort study of 468 patients

artículo científico publicado en 2020

Model-based approach to describe G-CSF effects in carboplatin-treated cancer patients.

artículo científico publicado en 2013

Model-based approach to early predict prolonged high grade neutropenia in carboplatin-treated patients and guide G-CSF prophylactic treatment

scientific article published on 04 September 2014

Modeling the variability of creatinine measurements improves estimates of the glomerular filtration rate.

artículo científico publicado en 2008

Multifactorial pharmacogenetic analysis in colorectal cancer patients receiving 5‐fluorouracil‐based therapy together with cetuximab–irinotecan ⬇️

artículo científico publicado el 1 de mayo de 2012

New advances in DPYD genotype and risk of severe toxicity under capecitabine.

artículo científico publicado en 2017

Overdose with 16,000 mg of imatinib mesylate.

artículo científico publicado en 2010

Pharmacokinetic Modeling of Plasma and Cerebrospinal Fluid Methotrexate after High-Dose Intravenous Infusion in Children ⬇️

artículo científico publicado el 1 de agosto de 1991

Pharmacokinetic and Pharmacogenetic Study of Etoposide in High-Dose Protocol (TI-CE) for Advanced Germ Cell Tumors

artículo científico publicado en 2020

Pharmacokinetic interaction between mitotane and etoposide in adrenal carcinoma: a pilot study

artículo científico publicado en 2018

Pharmacokinetic interaction between pazopanib and cisplatin regimen.

artículo científico publicado en 2016

Pharmacokinetic-Pharmacodynamic Relationships of Imatinib and Its Main Metabolite in Patients with Advanced Gastrointestinal Stromal Tumors

scientific article published on 01 October 2006

Pharmacokinetic/Pharmacodynamic modeling of abexinostat-induced thrombocytopenia across different patient populations: application for the determination of the maximum tolerated doses in both lymphoma and solid tumour patients

artículo científico publicado en 2014

Pharmacokinetics and impaired organic functions ⬇️

artículo científico publicado el 1 de noviembre de 2011

Pharmacokinetics of Irinotecan, Oxaliplatin and 5-Fluorouracil During Hepatic Artery Chronomodulated Infusion: A Translational European OPTILIV Study

artículo científico publicado en 2017

Pharmacokinetics of carboplatin in a patient suffering from advanced ovarian carcinoma with hemodialysis-dependent renal insufficiency

artículo científico publicado en 1994

Pharmacokinetics of irinotecan and its metabolites in human blood, bile, and urine

artículo científico publicado en 1995

Pharmacokinetics of oxaliplatin during open versus laparoscopically assisted heated intraoperative intraperitoneal chemotherapy (HIPEC): an experimental study.

artículo científico publicado en 2007

Pharmacokinetics of pazopanib administered in combination with bevacizumab

artículo científico publicado en 2014

Pharmacokinetics of rituximab associated with CHOP chemotherapy in B-cell non-Hodgkin lymphoma.

artículo científico publicado en 2009

Pharmacology of platinum compounds: differences between the three molecules and factors of interpatient variability ⬇️

artículo científico publicado el 1 de noviembre de 2011

Phase I and pharmacological study of an oxaliplatin and carboplatin combination in advanced malignancies.

artículo científico publicado en 2003

Phase-I study of a new schedule based on increasing days of topotecan administration associated with dose individualisation.

artículo científico publicado en 2005

Pilot study of neoadjuvant treatment with erlotinib in nonmetastatic head and neck squamous cell carcinoma.

artículo científico publicado en 2007

Plasma cystatin C is a marker of renal glomerular injury in children treated with cisplatin or ifosfamide

artículo científico publicado en 2020

Plasma vemurafenib exposure and pre-treatment hepatocyte growth factor level are two factors contributing to the early peripheral lymphocytes depletion in BRAF-mutated melanoma patients

artículo científico publicado en 2016

Polymorphisms in SLCO1B3 and NR1I2 as genetic determinants of hematotoxicity of carboplatin and paclitaxel combination.

artículo científico publicado en 2015

Population PKPD of paclitaxel and carboplatin in ovarian cancer patients: A study by the EORTC-PAMM-NDDG.

artículo científico publicado en 2007

Population Pharmacokinetic Approach Applied to Positron Emission Tomography: Computed Tomography for Tumor Tissue Identification in Patients with Glioma

artículo científico publicado en 2016

Population Pharmacokinetics of Tracers: A New Tool for Medical Imaging?

artículo científico publicado en 2016

Population analysis of erlotinib in adults and children reveals pharmacokinetic characteristics as the main factor explaining tolerance particularities in children.

artículo científico publicado en 2011

Population approaches in paediatrics

scientific article published on 01 December 2008

Population pharmacokinetic-pharmacodynamic model for neutropenia with patient subgroup identification: comparison across anticancer drugs.

artículo científico publicado en 2006

Population pharmacokinetics and pharmacodynamics of paclitaxel and carboplatin in ovarian cancer patients: a study by the European organization for research and treatment of cancer-pharmacology and molecular mechanisms group and new drug development

artículo científico publicado en 2007

Population pharmacokinetics of carboplatin in children

scientific article published on 01 April 1996

Population pharmacokinetics of erlotinib and its pharmacokinetic/pharmacodynamic relationships in head and neck squamous cell carcinoma.

artículo científico publicado en 2009

Population pharmacokinetics of peritoneal, plasma ultrafiltrated and protein-bound oxaliplatin concentrations in patients with disseminated peritoneal cancer after intraperitoneal hyperthermic chemoperfusion of oxaliplatin following cytoreductive su

artículo científico publicado en 2014

Population pharmacokinetics of rituximab with or without plasmapheresis in kidney patients with antibody-mediated disease.

artículo científico publicado en 2013

Population pharmacokinetics of topotecan: intraindividual variability in total drug.

artículo científico publicado en 2000

Population pharmacokinetics of total and unbound etoposide ⬇️

artículo científico publicado el 1 de enero de 1998

Possible excretion of etoposide via the intestinal mucosa

artículo científico publicado en 1999

Practical treatment guide for dose individualisation in cancer chemotherapy

scientific article published on 01 December 1998

Prediction of carboplatin clearance from standard morphological and biological patient characteristics

artículo científico publicado en 1995

Prevention of 5-fluorouracil-induced early severe toxicity by pre-therapeutic dihydropyrimidine dehydrogenase deficiency screening: The multiparametric approach is not convincing

artículo científico publicado en 2017

Prognostic Impact of Vitamin B6 Metabolism in Lung Cancer

article

Prognostic Impact of Vitamin B6 Metabolism in Lung Cancer

Quantification of topotecan by liquid chromatography-mass spectrometry (LC-MS). Application to intestinal transport using rat everted gut sacs.

artículo científico publicado en 2010

Quinine Unbound Concentration Has to Be Used for Therapeutic Drug Monitoring.

artículo científico publicado en 2016

Radiotherapy with concomitant continuous cisplatin infusion for unresectable tumors of the upper aerodigestive tract: results of a phase I study.

artículo científico publicado en 1997

Relation between unbound plasma concentrations and toxicity in a prolonged oral etoposide schedule.

artículo científico publicado en 1998

Renal insufficiency in elderly cancer patients: International Society of Geriatric Oncology clinical practice recommendations.

artículo científico publicado en 2007

Review of therapeutic drug monitoring of anticancer drugs part 1--cytotoxics

artículo científico publicado en 2014

Review of therapeutic drug monitoring of anticancer drugs part two--targeted therapies

artículo científico publicado en 2014

Ribavirin pharmacokinetics in renal and liver transplant patients: evidence that it depends on renal function

artículo científico publicado en 2004

Selective inhibition of HER2 inhibits AKT signal transduction and prolongs disease-free survival in a micrometastasis model of ovarian carcinoma

artículo científico publicado en 2005

Serum cystatin C is a better marker of topotecan clearance than serum creatinine.

artículo científico publicado en 2005

Setting the Dose of Checkpoint Inhibitors: The Role of Clinical Pharmacology

artículo científico publicado en 2020

Severe fluorouracil toxicity in a patient with dihydropyrimidine dehydrogenase deficiency

scientific article published on 01 October 1993

Should therapeutic drug monitoring of the unbound fraction of imatinib and its main active metabolite N-desmethyl-imatinib be developed?

artículo científico publicado en 2012

Simultaneous monitoring of pazopanib and its metabolites by UPLC-MS/MS.

artículo científico publicado en 2018

Sustained-release methotrexate for intracavitary chemotherapy.

artículo científico publicado en 1994

Target-driven exploratory study of imatinib mesylate in children with solid malignancies by the Innovative Therapies for Children with Cancer (ITCC) European Consortium.

artículo científico publicado en 2009

The scientific basis of body surface area-based dosing

artículo científico publicado en 2014

Therapeutic Drug Monitoring of Carboplatin in High-Dose Protocol (TI-CE) for Advanced Germ Cell Tumors: Pharmacokinetic Results of a Phase II Multicenter Study

artículo científico publicado en 2017

Therapeutic drug monitoring and dose adaptation of cisplatin in a newborn with hepatoblastoma: a case report

artículo científico publicado en 2018

Therapeutic drug monitoring in cancer--are we missing a trick?

artículo científico publicado en 2014

Tissue distribution and pharmacokinetics of an ATWLPPR-conjugated chlorin-type photosensitizer targeting neuropilin-1 in glioma-bearing nude mice.

artículo científico publicado en 2008

Toxicity patterns of cytotoxic drugs.

artículo científico publicado en 2003

Treatment of leptomeningeal metastasis with intraventricular administration of depot cytarabine (DTC 101). A phase I study.

artículo científico publicado en 1993

Urinary cystatin C can improve the renal safety follow-up of tenofovir-treated patients.

artículo científico publicado en 2009

Vinorelbine/docetaxel combination treatment of metastatic breast cancer: a phase I study

scientific article published on 25 November 2006

[5-fluorouracil therapeutic drug monitoring: Update and recommendations of the STP-PT group of the SFPT and the GPCO-Unicancer]

artículo científico publicado en 2018

[Anticancer drug dose individualisation: from body surface area to physiology]

artículo científico publicado en 2008

[Importance of hyperthermic intraperitoneal chemotherapy (HIPEC) in ovarian cancer]

artículo científico publicado en 2009

[Level of evidence for therapeutic drug monitoring of cisplatin]

artículo científico publicado en 2010

[Pharmacological bases of intraperitoneal chemotherapy]

artículo científico publicado en 2009

Lista de obras de Etienne Chatelut

A Phase I, Dose-Escalation Trial of Pazopanib in Combination with Cisplatin in Patients with Advanced Solid Tumors: A UNICANCER Study.

A limited sampling strategy for determining carboplatin AUC and monitoring drug dosage.

A limited-sampling method for evaluation of the area under the curve of ultrafilterable carboplatin in children

A limited-sampling strategy for estimation of etoposide pharmacokinetics in cancer patients.

A pharmacologically guided phase I study of carboplatin in combination with methotrexate and vinblastine in advanced urothelial cancer.

A phase I dose-escalating and pharmacokinetic study of docetaxel and vinorelbine as first-line chemotherapy for metastatic breast cancer.

A universal formula based on cystatin C to perform individual dosing of carboplatin in normal weight, underweight, and obese patients.

An UPLC-MS/MS method for separation and accurate quantification of tamoxifen and its metabolites isomers

Antiretroviral unbound concentration during pregnancy: piece of interest in the puzzle?

Application of hematological toxicity modeling in clinical development of abexinostat (S-78454, PCI-24781), a new histone deacetylase inhibitor.

Cellular pharmacokinetics of doxorubicin in patients with chronic lymphocytic leukemia: comparison of bolus administration and continuous infusion

Cerebrospinal fluid concentrations of carboplatin in a patient without blood-brain barrier disruption

Cetuximab pharmacokinetic/pharmacodynamics relationships in advanced head and neck carcinoma patients

Characterization of CPT-11 converting carboxylesterase activity in colon tumor and normal tissues: comparison with p-nitro-phenylacetate converting carboxylesterase activity

Circulating oxysterol metabolites as potential new surrogate markers in patients with hormone receptor-positive breast cancer: Results of the OXYTAM study.

Clinical Pharmacokinetics and Pharmacodynamics of Dabrafenib

Co-variables influencing 5-fluorouracil clearance during continuous venous infusion. A NONMEM analysis.

Comparison of nonlinear mixed-effect and non-parametric expectation maximisation modelling for Bayesian estimation of carboplatin clearance in children.

Comparison of the pharmacokinetics and efficacy of irinotecan after administration by the intravenous versus intraperitoneal route in mice

Continuous Infusion of Cilengitide Plus Chemoradiotherapy for Patients With Stage III Non-Small-cell Lung Cancer: A Phase I Study.

Contribution of the MDRD equation and of cystatin C for renal function estimates in cancer patients.

Correlation between Bevacizumab Exposure and Survival does not necessarily imply Causality. Letter to the Editor

Determination of dolutegravir's unbound fraction in human plasma using validated equilibrium dialysis and LC-MS/MS methods

Determination of plasma unbound fraction of voriconazole in patients treated with a prophylactic or a curative treatment

Determination of unbound fraction of imatinib and N-desmethyl imatinib, validation of an UPLC-MS/MS assay and ultrafiltration method

Determination of unbound fraction of pazopanib in vitro and in cancer patients reveals albumin as the main binding site

Development and validation of an UHPLC-MS/MS method for simultaneous quantification of ibrutinib and its dihydrodiol-metabolite in human cerebrospinal fluid

Dexamethasone as a probe for CYP3A4 metabolism: evidence of gender effect

Dexamethasone as a probe for docetaxel clearance.

Dihydropyrimidine dehydrogenase activity in normal, inflammatory and tumour tissues of colon and liver in humans

Diversity of dose-individualization and therapeutic drug monitoring practices of platinum compounds: a review

Dose and time dependencies of 5-fluorouracil pharmacokinetics

Dose banding as an alternative to body surface area-based dosing of chemotherapeutic agents

Efavirenz and Lopinavir Levels in HIV-Infected Women and Their Nursing Infants, in Mali

Escalating dose of mitoxantrone with high-dose cyclophosphamide, carmustine, and etoposide in patients with refractory lymphoma undergoing autologous bone marrow transplantation

Evaluation of a peptide ELISA for the detection of rituximab in serum.

Evaluation of the Interaction of Amino Acid Infusion on 177Lu-Dotatate Pharmacokinetics in Patients with Gastroenteropancreatic Neuroendocrine Tumors

Extended CSF cytarabine exposure following intrathecal administration of DTC 101.

Factors accelerating liver fibrosis progression in renal transplant patients receiving ribavirin monotherapy for chronic hepatitis C.

Factors affecting pharmacokinetic variability of oral topotecan: a population analysis

GFR is better estimated by considering both serum cystatin C and creatinine levels.

Genotyping of a family with a novel deleterious DPYD mutation supports the pretherapeutic screening of DPD deficiency with dihydrouracil/uracil ratio.

High Resectability Rate of Initially Unresectable Colorectal Liver Metastases After UGT1A1-Adapted High-Dose Irinotecan Combined with LV5FU2 and Cetuximab: A Multicenter Phase II Study (ERBIFORT)

How can we best monitor 5-FU administration to maximize benefit to risk ratio?

How to predict carboplatin clearance from standard morphological and biological characteristics in obese patients.

Impact of the biochemical assay for serum creatinine measurement on the individual carboplatin dosing ⬇️

Individual dosing of carboplatin based on drug monitoring in children receiving high-dose chemotherapy.

Influence of HCV genotype 1 subtypes on the virus response to PEG interferon alpha‐2a plus ribavirin therapy ⬇️

Influence of methotrexate exposure on outcome in patients treated with MBVP chemotherapy for primary central nervous system lymphoma

Inhibition of OCT2, MATE1 and MATE2-K as a possible mechanism of drug interaction between pazopanib and cisplatin

Innovative Therapies for Children with Cancer pediatric phase I study of erlotinib in brainstem glioma and relapsing/refractory brain tumors

Interest of cystatin C for individual dosing of anticancer drugs cleared by the kidneys

International Society of Geriatric Oncology Chemotherapy Taskforce: evaluation of chemotherapy in older patients--an analysis of the medical literature.

Intraindividual Pharmacokinetic Variability: Focus on Small-Molecule Kinase Inhibitors.

Investigating the potential impact of dose banding for systemic anti-cancer therapy in the paediatric setting based on pharmacokinetic evidence.

Irreversible hepatotoxicity after administration of trabectedin to a pleiomorphic sarcoma patient with a rare ABCC2 polymorphism: a case report.

Is the unbound concentration of atazanavir of interest in therapeutic drug monitoring?

Life-threatening complications after high-dose methotrexate and the benefits of glucarpidase as salvage therapy: a cohort study of 468 patients

Model-based approach to describe G-CSF effects in carboplatin-treated cancer patients.

Model-based approach to early predict prolonged high grade neutropenia in carboplatin-treated patients and guide G-CSF prophylactic treatment

Modeling the variability of creatinine measurements improves estimates of the glomerular filtration rate.

Multifactorial pharmacogenetic analysis in colorectal cancer patients receiving 5‐fluorouracil‐based therapy together with cetuximab–irinotecan ⬇️

New advances in DPYD genotype and risk of severe toxicity under capecitabine.

Overdose with 16,000 mg of imatinib mesylate.

Pharmacokinetic Modeling of Plasma and Cerebrospinal Fluid Methotrexate after High-Dose Intravenous Infusion in Children ⬇️

Pharmacokinetic and Pharmacogenetic Study of Etoposide in High-Dose Protocol (TI-CE) for Advanced Germ Cell Tumors

Pharmacokinetic interaction between mitotane and etoposide in adrenal carcinoma: a pilot study

Pharmacokinetic interaction between pazopanib and cisplatin regimen.

Pharmacokinetic-Pharmacodynamic Relationships of Imatinib and Its Main Metabolite in Patients with Advanced Gastrointestinal Stromal Tumors

Pharmacokinetic/Pharmacodynamic modeling of abexinostat-induced thrombocytopenia across different patient populations: application for the determination of the maximum tolerated doses in both lymphoma and solid tumour patients

Pharmacokinetics and impaired organic functions ⬇️

Pharmacokinetics of Irinotecan, Oxaliplatin and 5-Fluorouracil During Hepatic Artery Chronomodulated Infusion: A Translational European OPTILIV Study

Pharmacokinetics of carboplatin in a patient suffering from advanced ovarian carcinoma with hemodialysis-dependent renal insufficiency

Pharmacokinetics of irinotecan and its metabolites in human blood, bile, and urine

Pharmacokinetics of oxaliplatin during open versus laparoscopically assisted heated intraoperative intraperitoneal chemotherapy (HIPEC): an experimental study.

Pharmacokinetics of pazopanib administered in combination with bevacizumab

Pharmacokinetics of rituximab associated with CHOP chemotherapy in B-cell non-Hodgkin lymphoma.

Pharmacology of platinum compounds: differences between the three molecules and factors of interpatient variability ⬇️

Phase I and pharmacological study of an oxaliplatin and carboplatin combination in advanced malignancies.