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Lista de obras de Lynn Morris

4E10-resistant variants in a human immunodeficiency virus type 1 subtype C-infected individual with an anti-membrane-proximal external region-neutralizing antibody response

artículo científico publicado en 2007

A fusion intermediate gp41 immunogen elicits neutralizing antibodies to HIV-1

artículo científico publicado en 2014

A model of directional selection applied to the evolution of drug resistance in HIV-1.

artículo científico publicado en 2007

A reliable phenotype predictor for human immunodeficiency virus type 1 subtype C based on envelope V3 sequences

artículo científico publicado en 2006

AIDS-related mycoses: the way forward

artículo científico publicado en 2014

Ability to develop broadly neutralizing HIV-1 antibodies is not restricted by the germline Ig gene repertoire

artículo científico publicado en 2015

Active-site mutations in the South african human immunodeficiency virus type 1 subtype C protease have a significant impact on clinical inhibitor binding: kinetic and thermodynamic study

artículo científico publicado en 2008

Adherence and virologic suppression during the first 24 weeks on antiretroviral therapy among women in Johannesburg, South Africa - a prospective cohort study

artículo científico publicado en 2011

Adherence to drug-refill is a useful early warning indicator of virologic and immunologic failure among HIV patients on first-line ART in South Africa

artículo científico publicado en 2011

Afri-Can Forum 2 : Johannesburg, South Africa. 16-18 February 2015

Amino Acid Changes in the HIV-1 gp41 Membrane Proximal Region Control Virus Neutralization Sensitivity

scientific article published on 31 August 2016

Analysis of a clonal lineage of HIV-1 envelope V2/V3 conformational epitope-specific broadly neutralizing antibodies and their inferred unmutated common ancestors

artículo científico publicado en 2011

Antibody and cellular responses to HIV vaccine regimens with DNA plasmid as compared with ALVAC priming: An analysis of two randomized controlled trials

artículo científico publicado en 2020

Antibody light-chain-restricted recognition of the site of immune pressure in the RV144 HIV-1 vaccine trial is phylogenetically conserved

artículo científico publicado en 2014

Antibody specificities associated with neutralization breadth in plasma from human immunodeficiency virus type 1 subtype C-infected blood donors

artículo científico publicado en 2009

Antiretroviral drug resistance surveillance among drug-naive HIV-1-infected individuals in Gauteng Province, South Africa in 2002 and 2004.

artículo científico publicado en 2008

Assessing the safety and pharmacokinetics of the anti-HIV monoclonal antibody CAP256V2LS alone and in combination with VRC07-523LS and PGT121 in South African women: study protocol for the first-in-human CAPRISA 012B phase I clinical trial

scientific article published on 26 November 2020

Binding of the mannose-specific lectin, griffithsin, to HIV-1 gp120 exposes the CD4-binding site

artículo científico publicado en 2011

Broad neutralization by a combination of antibodies recognizing the CD4 binding site and a new conformational epitope on the HIV-1 envelope protein

artículo científico publicado en 2012

Broad neutralization of human immunodeficiency virus type 1 mediated by plasma antibodies against the gp41 membrane proximal external region

artículo científico publicado en 2009

Broadly neutralizing antibodies targeting the HIV-1 envelope V2 apex confer protection against a clade C SHIV challenge

artículo científico publicado en 2017

Broadly neutralizing antibody specificities detected in the genital tract of HIV-1 infected women

artículo científico publicado en 2016

Characterization and selection of HIV-1 subtype C isolates for use in vaccine development

artículo científico publicado en 2003

Characterization of anti-HIV-1 neutralizing and binding antibodies in chronic HIV-1 subtype C infection

artículo científico publicado en 2012

Characterization of human immunodeficiency virus type 1 from a previously unexplored region of South Africa with a high HIV prevalence

artículo científico publicado en 2005

Clinical and virological response to antiretroviral drugs among HIV patients on first-line treatment in Dar-es-Salaam, Tanzania

artículo científico publicado en 2014

Common helical V1V2 conformations of HIV-1 Envelope expose the α4β7 binding site on intact virions

artículo científico publicado en 2018

Comparative Neutralization Sensitivity of Indian and South African HIV-1 Clade C Viruses to Plasma Antibodies from Chronically Infected Indian Donors

article

Comparison of viral Env proteins from acute and chronic infections with subtype C human immunodeficiency virus type 1 identifies differences in glycosylation and CCR5 utilization and suggests a new strategy for immunogen design

artículo científico publicado en 2013

Concordance between allele-specific PCR and ultra-deep pyrosequencing for the detection of HIV-1 non-nucleoside reverse transcriptase inhibitor resistance mutations

artículo científico publicado en 2014

Cooperation between Strain-Specific and Broadly Neutralizing Responses Limited Viral Escape and Prolonged the Exposure of the Broadly Neutralizing Epitope

artículo científico publicado en 2017

Coreceptor usage and biological phenotypes of HIV-1 isolates

artículo científico publicado en 2002

Correction for Anthony et al., "Cooperation between Strain-Specific and Broadly Neutralizing Responses Limited Viral Escape and Prolonged the Exposure of the Broadly Neutralizing Epitope".

artículo científico publicado en 2018

Correction for Hraber et al., "Panels of HIV-1 Subtype C Env Reference Strains for Standardized Neutralization Assessments".

artículo científico publicado en 2017

Correction: Features of Recently Transmitted HIV-1 Clade C Viruses that Impact Antibody Recognition: Implications for Active and Passive Immunization

artículo científico publicado en 2017

Correction: Geographic and Temporal Trends in the Molecular Epidemiology and Genetic Mechanisms of Transmitted HIV-1 Drug Resistance: An Individual-Patient- and Sequence-Level Meta-Analysis

artículo científico publicado en 2015

Cross-reactive coronavirus antibodies with diverse epitope specificities and extra-neutralization functions

artículo científico publicado en 2020

Cytotoxicological analysis of a gp120 binding aptamer with cross-clade human immunodeficiency virus type 1 entry inhibition properties: comparison to conventional antiretrovirals

artículo científico publicado en 2009

Decay of K103N mutants in cellular DNA and plasma RNA after single-dose nevirapine to reduce mother-to-child HIV transmission

artículo científico publicado en 2006

Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization

artículo científico publicado en 2013

Detection of low-level K65R variants in nucleoside reverse transcriptase inhibitor-naive chronic and acute HIV-1 subtype C infections

artículo científico publicado en 2011

Development of broadly neutralizing antibodies from autologous neutralizing antibody responses in HIV infection

artículo científico publicado en 2014

Development of phenotypic HIV-1 drug resistance after exposure to single-dose nevirapine

artículo científico publicado en 2008

Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies

artículo científico publicado en 2014

Differences in HIV type 1 neutralization breadth in 2 geographically distinct cohorts in Africa

artículo científico publicado en 2014

Differential V2-directed antibody responses in non-human primates infected with SHIVs or immunized with diverse HIV vaccines

artículo científico publicado en 2022

Discordances between interpretation algorithms for genotypic resistance to protease and reverse transcriptase inhibitors of human immunodeficiency virus are subtype dependent

artículo científico publicado en 2006

Does tuberculosis increase HIV load?

artículo científico publicado en 2004

Drug resistance among newly diagnosed HIV-infected children in the era of more efficacious antiretroviral prophylaxis

artículo científico publicado en 2014

Drug resistance patterns and virus re-suppression among HIV-1 subtype C infected patients receiving non-nucleoside reverse transcriptase inhibitors in South Africa

artículo científico publicado en 2011

Durable HIV RNA resuppression after virologic failure while remaining on a first-line regimen: a cohort study

artículo científico publicado en 2014

Early virological suppression despite high frequency NNRTI resistance following perinatal prophylaxis in HIV-infected African infants

article

Early virological suppression with three-class antiretroviral therapy in HIV-infected African infants

artículo científico publicado en 2008

Effect of HIV Envelope Vaccination on the Subsequent Antibody Response to HIV Infection

scientific article published on 29 January 2020

Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women

artículo científico publicado en 2010

Effects of Darwinian Selection and Mutability on Rate of Broadly Neutralizing Antibody Evolution during HIV-1 Infection

artículo científico publicado en 2016

Emergence of drug-resistant HIV-1 after intrapartum administration of single-dose nevirapine is substantially underestimated

artículo científico publicado en 2005

Establishing a cohort at high risk of HIV infection in South Africa: challenges and experiences of the CAPRISA 002 acute infection study

artículo científico publicado en 2008

Evaluation of an oligonucleotide ligation assay for detection of mutations in HIV-1 subtype C individuals who have high level resistance to nucleoside reverse transcriptase inhibitors and non-nucleoside reverse transcriptase inhibitors

artículo científico publicado en 2005

Evaluation of sequence ambiguities of the HIV-1 pol gene as a method to identify recent HIV-1 infection in transmitted drug resistance surveys

artículo científico publicado en 2013

Evidence for both Intermittent and Persistent Compartmentalization of HIV-1 in the Female Genital Tract

scientific article published on 01 May 2019

Evolution of an HIV glycan-dependent broadly neutralizing antibody epitope through immune escape

artículo científico publicado en 2012

Extreme genetic divergence is required for coreceptor switching in HIV-1 subtype C.

artículo científico publicado en 2011

Features of Recently Transmitted HIV-1 Clade C Viruses that Impact Antibody Recognition: Implications for Active and Passive Immunization

artículo científico publicado en 2016

Full-length genome analysis of HIV-1 subtype C utilizing CXCR4 and intersubtype recombinants isolated in South Africa

artículo científico publicado en 2002

Functional and genetic analysis of coreceptor usage by dualtropic HIV-1 subtype C isolates

artículo científico publicado en 2009

Genetic Changes in HIV-1 Gag-Protease Associated with Protease Inhibitor-Based Therapy Failure in Pediatric Patients

artículo científico publicado en 2015

Genetic and neutralization properties of subtype C human immunodeficiency virus type 1 molecular env clones from acute and early heterosexually acquired infections in Southern Africa

artículo científico publicado en 2006

Genetic characteristics of HIV-1 subtype C envelopes inducing cross-neutralizing antibodies

artículo científico publicado en 2007

Genetic characteristics of the V3 region associated with CXCR4 usage in HIV-1 subtype C isolates

artículo científico publicado en 2006

Genotypic and phenotypic characterization of viral isolates from HIV-1 subtype C-infected children with slow and rapid disease progression

artículo científico publicado en 2006

Genotypic resistance at viral rebound among patients who received lopinavir/ritonavir-based or efavirenz-based first antiretroviral therapy in South Africa

artículo científico publicado en 2011

Geographic and temporal trends in the molecular epidemiology and genetic mechanisms of transmitted HIV-1 drug resistance: an individual-patient- and sequence-level meta-analysis

artículo científico publicado en 2015

HIV Superinfection Drives De Novo Antibody Responses and Not Neutralization Breadth

article

HIV broadly neutralizing antibody targets

artículo científico publicado en 2015

HIV disease progression in seroconvertors from the CAPRISA 004 tenofovir gel pre-exposure prophylaxis trial

artículo científico publicado en 2015

HIV type 1 subtype C drug resistance among pediatric and adult South African patients failing antiretroviral therapy

artículo científico publicado en 2008

HIV-1 Subtype A, D, G, AG and unclassified sequences identified in South Africa

scientific article published on 01 June 2002

HIV-1 Subtype C-Infected Children with Exceptional Neutralization Breadth Exhibit Polyclonal Responses Targeting Known Epitopes

article

HIV-1 clade C escapes broadly neutralizing autologous antibodies with N332 glycan specificity by distinct mechanisms

artículo científico publicado en 2016

HIV-1 drug resistance at antiretroviral treatment initiation in children previously exposed to single-dose nevirapine

artículo científico publicado en 2011

HIV-1 envelope gp41 antibodies can originate from terminal ileum B cells that share cross-reactivity with commensal bacteria

artículo científico publicado en 2014

HIV-1 pol mutation frequency by subtype and treatment experience: extension of the HIVseq program to seven non-B subtypes

artículo científico publicado en 2006

HIV-1 re-suppression on a first-line regimen despite the presence of phenotypic drug resistance

scientific article published on 18 June 2020

HIV-1 subtype C reverse transcriptase sequences from drug-naive pregnant women in South Africa

artículo científico publicado en 2002

HIV-1 subtype C unproductively infects human cardiomyocytes in vitro and induces apoptosis mitigated by an anti-Gp120 aptamer

artículo científico publicado en 2014

HIV-1 superinfection can occur in the presence of broadly neutralizing antibodies

artículo científico publicado en 2017

HIV-specific Fc effector function early in infection predicts the development of broadly neutralizing antibodies.

artículo científico publicado en 2018

HIVR4P 2016, Partnering for Prevention: Conference Summary and Highlights

artículo científico publicado en 2017

High specificity of V3 serotyping among human immunodeficiency virus type-1 subtype C infected patients with varying disease status and viral phenotype

artículo científico publicado en 2006

High titer HIV-1 V3-specific antibodies with broad reactivity but low neutralizing potency in acute infection and following vaccination

artículo científico publicado en 2009

High-Frequency, Functional HIV-Specific T-Follicular Helper and Regulatory Cells Are Present Within Germinal Centers in Children but Not Adults

article

Highly complex neutralization determinants on a monophyletic lineage of newly transmitted subtype C HIV-1 Env clones from India

artículo científico publicado en 2009

Human immunodeficiency virus type 2 (HIV-2)/HIV-1 envelope chimeras detect high titers of broadly reactive HIV-1 V3-specific antibodies in human plasma

artículo científico publicado en 2008

Human immunodeficiency virus-1 RNA levels and CD4 lymphocyte counts, during treatment for active tuberculosis, in South African patients

artículo científico publicado en 2003

Human immunodeficiency virus-specific gamma interferon enzyme-linked immunospot assay responses targeting specific regions of the proteome during primary subtype C infection are poor predictors of the course of viremia and set point

artículo científico publicado en 2008

Identification of broadly neutralizing antibody epitopes in the HIV-1 envelope glycoprotein using evolutionary models

artículo científico publicado en 2013

IgG3 enhances neutralization potency and Fc effector function of an HIV V2-specific broadly neutralizing antibody

scientific article published on 16 December 2019

Immune correlates of the Thai RV144 HIV vaccine regimen in South Africa

scientific article published on 01 September 2019

Immunoglobulin gene insertions and deletions in the affinity maturation of HIV-1 broadly reactive neutralizing antibodies

artículo científico publicado en 2014

Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: results of a global collaboration

artículo científico publicado en 2005

Impact of drug resistance-associated amino acid changes in HIV-1 subtype C on susceptibility to newer nonnucleoside reverse transcriptase inhibitors

artículo científico publicado en 2014

In vitro generation of HIV type 1 subtype C isolates resistant to enfuvirtide

artículo científico publicado en 2005

Incidence of HIV‐1 Dual Infection and Its Association with Increased Viral Load Set Point in a Cohort of HIV‐1 Subtype C–Infected Female Sex Workers

article

Initial B-cell responses to transmitted human immunodeficiency virus type 1: virion-binding immunoglobulin M (IgM) and IgG antibodies followed by plasma anti-gp41 antibodies with ineffective control of initial viremia

artículo científico publicado en 2008

Insensitivity of paediatric HIV-1 subtype C viruses to broadly neutralising monoclonal antibodies raised against subtype B

artículo científico publicado en 2006

International network for comparison of HIV neutralization assays: the NeutNet report

artículo científico publicado en 2009

International network for comparison of HIV neutralization assays: the NeutNet report II

artículo científico publicado en 2012

Isolation of a human anti-HIV gp41 membrane proximal region neutralizing antibody by antigen-specific single B cell sorting

artículo científico publicado en 2011

Isolation of a monoclonal antibody that targets the alpha-2 helix of gp120 and represents the initial autologous neutralizing-antibody response in an HIV-1 subtype C-infected individual

artículo científico publicado en 2011

Limited neutralizing antibody specificities drive neutralization escape in early HIV-1 subtype C infection

artículo científico publicado en 2009

Longitudinal analysis of HIV type 1 subtype C envelope sequences from South Africa

artículo científico publicado en 2007

Low frequency of the V106M mutation among HIV-1 subtype C-infected pregnant women exposed to nevirapine

artículo científico publicado en 2003

Mannose-rich glycosylation patterns on HIV-1 subtype C gp120 and sensitivity to the lectins, Griffithsin, Cyanovirin-N and Scytovirin

artículo científico publicado en 2010

Mapping Polyclonal HIV-1 Antibody Responses via Next-Generation Neutralization Fingerprinting

artículo científico publicado en 2017

Mechanisms of HIV-1 subtype C resistance to GRFT, CV-N and SVN.

artículo científico publicado en 2013

Mimicry of an HIV broadly neutralizing antibody epitope with a synthetic glycopeptide.

artículo científico publicado en 2017

Multi-Donor Longitudinal Antibody Repertoire Sequencing Reveals the Existence of Public Antibody Clonotypes in HIV-1 Infection.

artículo científico publicado en 2018

Multiple pathways of escape from HIV broadly cross-neutralizing V2-dependent antibodies

artículo científico publicado en 2013

N-linked glycan modifications in gp120 of human immunodeficiency virus type 1 subtype C render partial sensitivity to 2G12 antibody neutralization

artículo científico publicado en 2007

Nature of nonfunctional envelope proteins on the surface of human immunodeficiency virus type 1.

artículo científico publicado en 2006

Neutralization Breadth and Potency of Single-Chain Variable Fragments Derived from Broadly Neutralizing Antibodies Targeting Multiple Epitopes on the HIV-1 Envelope

artículo científico publicado en 2020

Neutralization tiers of HIV-1.

artículo científico publicado en 2017

Neutralizing and other antiviral antibodies in HIV-1 infection and vaccination

artículo científico publicado en 2007

Neutralizing antibodies generated during natural HIV-1 infection: good news for an HIV-1 vaccine?

artículo científico publicado en 2009

Neutralizing antibody responses to HIV-1 infection

artículo científico publicado en 2002

New Member of the V1V2-Directed CAP256-VRC26 Lineage That Shows Increased Breadth and Exceptional Potency

artículo científico publicado en 2015

Nonprogressing HIV-infected children share fundamental immunological features of nonpathogenic SIV infection

artículo científico publicado en 2016

Novel Cyclopropyl-Indole Derivatives as HIV Non-Nucleoside Reverse Transcriptase Inhibitors.

artículo científico publicado en 2012

Novel indole based NNRTIs with improved potency against wild type and resistant HIV.

artículo científico publicado en 2014

Ontogeny-based immunogens for the induction of V2-directed HIV broadly neutralizing antibodies

scientific article published on January 2017

Optimal Combinations of Broadly Neutralizing Antibodies for Prevention and Treatment of HIV-1 Clade C Infection

artículo científico publicado en 2016

Optimization of allele-specific PCR using patient-specific HIV consensus sequences for primer design

artículo científico publicado en 2009

Panels of HIV-1 Subtype C Env Reference Strains for Standardized Neutralization Assessments

artículo científico publicado en 2017

Persistent minority K103N mutations among women exposed to single-dose nevirapine and virologic response to nonnucleoside reverse-transcriptase inhibitor-based therapy

artículo científico publicado en 2009

Plant-based production of highly potent anti-HIV antibodies with engineered posttranslational modifications

scientific article published on 10 April 2020

Plasma CXCL13 but Not B Cell Frequencies in Acute HIV Infection Predicts Emergence of Cross-Neutralizing Antibodies

artículo científico publicado en 2017

Polyclonal B cell responses to conserved neutralization epitopes in a subset of HIV-1-infected individuals

artículo científico publicado en 2011

Polymorphisms in Nef Associated with Different Clinical Outcomes in HIV Type 1 Subtype C-Infected Children

article

Population-based surveillance of HIV drug resistance emerging on treatment and associated factors at sentinel antiretroviral therapy sites in Namibia

artículo científico publicado en 2015

Positive Selection at Key Residues in the HIV Envelope Distinguishes Broad and Strain-Specific Plasma Neutralizing Antibodies

article

Potent and broad HIV-neutralizing antibodies in memory B cells and plasma

artículo científico publicado en 2017

Potent and broad neutralization of HIV-1 subtype C by plasma antibodies targeting a quaternary epitope including residues in the V2 loop

artículo científico publicado en 2011

Predicted genotypic resistance to the novel entry inhibitor, BMS-378806, among HIV-1 isolates of subtypes A to G.

artículo científico publicado en 2004

Prime-Boost Immunizations with DNA, Modified Vaccinia Virus Ankara, and Protein-Based Vaccines Elicit Robust HIV-1 Tier 2 Neutralizing Antibodies against the CAP256 Superinfecting Virus

article

Profiling the specificity of neutralizing antibodies in a large panel of plasmas from patients chronically infected with human immunodeficiency virus type 1 subtypes B and C.

artículo científico publicado en 2008

Prospects for passive immunity to prevent HIV infection

artículo científico publicado en 2017

Randomized Cross-Sectional Study to Compare HIV-1 Specific Antibody and Cytokine Concentrations in Female Genital Secretions Obtained by Menstrual Cup and Cervicovaginal Lavage

artículo científico publicado en 2015

Randomized trial of time-limited interruptions of protease inhibitor-based antiretroviral therapy (ART) vs. continuous therapy for HIV-1 infection

artículo científico publicado en 2011

Rapid Detection of Common HIV-1 Drug Resistance Mutations by Use of High-Resolution Melting Analysis and Unlabeled Probes

scientific article published on 26 October 2016

Rapid development of antiretroviral drug resistance mutations in HIV-infected children less than two years of age initiating protease inhibitor-based therapy in South Africa

artículo científico publicado en 2011

Rapid disease progression in HIV-1 subtype C-infected South African women

artículo científico publicado en 2014

Rates of virological suppression and drug resistance in adult HIV-1-positive patients attending primary healthcare facilities in KwaZulu-Natal, South Africa

artículo científico publicado en 2017

Rates of virological suppression and drug resistance in adult HIV-1-positive patients attending primary healthcare facilities in KwaZulu-Natal, South Africa.

artículo científico publicado en 2017

Recommendations for the design and use of standard virus panels to assess neutralizing antibody responses elicited by candidate human immunodeficiency virus type 1 vaccines

artículo científico publicado en 2005

Regional clustering of shared neutralization determinants on primary isolates of clade C human immunodeficiency virus type 1 from South Africa

artículo científico publicado en 2002

Resistance mutational analysis of HIV type 1 subtype C among rural South African drug-naive patients prior to large-scale availability of antiretrovirals

artículo científico publicado en 2006

Resistance to tenofovir-based regimens during treatment failure of subtype C HIV-1 in South Africa

artículo científico publicado en 2013

Reuse of nevirapine in exposed HIV-infected children after protease inhibitor-based viral suppression: a randomized controlled trial

artículo científico publicado en 2010

Safety and immune responses after a 12-month booster in healthy HIV-uninfected adults in HVTN 100 in South Africa: A randomized double-blind placebo-controlled trial of ALVAC-HIV (vCP2438) and bivalent subtype C gp120/MF59 vaccines

artículo científico publicado en 2020

Select gp120 V2 domain specific antibodies derived from HIV and SIV infection and vaccination inhibit gp120 binding to α4β7

article

Selection and persistence of viral resistance in HIV-infected children after exposure to single-dose nevirapine

artículo científico publicado en 2007

Sensitive tenofovir resistance screening of HIV-1 from the genital and blood compartments of women with breakthrough infections in the CAPRISA 004 tenofovir gel trial

artículo científico publicado en 2014

Sensitivity of HIV type 1 subtype C isolates to the entry inhibitor T-20.

artículo científico publicado en 2004

Sequencing HIV-neutralizing antibody exons and introns reveals detailed aspects of lineage maturation

scientific article published in Nature Communications

Sequential Immunization with gp140 Boosts Immune Responses Primed by Modified Vaccinia Ankara or DNA in HIV-Uninfected South African Participants

artículo científico publicado en 2016

Serum glycan-binding IgG antibodies in HIV-1 infection and during the development of broadly neutralizing responses

artículo científico publicado en 2017

Somatic hypermutation to counter a globally rare viral immunotype drove off-track antibodies in the CAP256-VRC26 HIV-1 V2-directed bNAb lineage

artículo científico publicado en 2019

South African HIV-1 subtype C transmitted variants with a specific V2 motif show higher dependence on α4β7 for replication

artículo científico publicado en 2015

Specificity of the autologous neutralizing antibody response

artículo científico publicado en 2009

Staged induction of HIV-1 glycan-dependent broadly neutralizing antibodies.

artículo científico publicado en 2017

Strain-Specific V3 and CD4 Binding Site Autologous HIV-1 Neutralizing Antibodies Select Neutralization-Resistant Viruses

artículo científico publicado en 2015

Structural Constraints of Vaccine-Induced Tier-2 Autologous HIV Neutralizing Antibodies Targeting the Receptor-Binding Site

artículo científico publicado en 2015

Structure and immune recognition of trimeric pre-fusion HIV-1 Env.

artículo científico publicado en 2014

Structure of Super-Potent Antibody CAP256-VRC26.25 in Complex with HIV-1 Envelope Reveals a Combined Mode of Trimer-Apex Recognition

scientific article published on 01 April 2020

Structure of an N276-Dependent HIV-1 Neutralizing Antibody Targeting a Rare V5 Glycan Hole Adjacent to the CD4 Binding Site

artículo científico publicado en 2016

Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design

artículo científico publicado en 2016

Subtype C ALVAC-HIV and bivalent subtype C gp120/MF59 HIV-1 vaccine in low-risk, HIV-uninfected, South African adults: a phase 1/2 trial.

artículo científico publicado en 2018

Subtype C gp140 Vaccine Boosts Immune Responses Primed by the South African AIDS Vaccine Initiative DNA-C2 and MVA-C HIV Vaccines after More than a 2-Year Gap

artículo científico publicado en 2016

Switching children previously exposed to nevirapine to nevirapine-based treatment after initial suppression with a protease-inhibitor-based regimen: long-term follow-up of a randomised, open-label trial

artículo científico publicado en 2012

The CCR5 and CXCR4 coreceptors are both used by human immunodeficiency virus type 1 primary isolates from subtype C.

artículo científico publicado en 2003

The adjuvant AlhydroGel elicits higher antibody titres than AddaVax when combined with HIV-1 subtype C gp140 from CAP256

scientific article published in PLoS ONE

The c3-v4 region is a major target of autologous neutralizing antibodies in human immunodeficiency virus type 1 subtype C infection

artículo científico publicado en 2007

The development of CD4 binding site antibodies during HIV-1 infection

artículo científico publicado en 2012

The lectins griffithsin, cyanovirin-N and scytovirin inhibit HIV-1 binding to the DC-SIGN receptor and transfer to CD4(+) cells

artículo científico publicado en 2011

The neutralization breadth of HIV-1 develops incrementally over four years and is associated with CD4+ T cell decline and high viral load during acute infection

artículo científico publicado en 2011

The use of dried blood spot specimens for HIV-1 drug resistance genotyping in young children initiating antiretroviral therapy

artículo científico publicado en 2015

Transmission Rates in Consecutive Pregnancies Exposed to Single-Dose Nevirapine in Soweto, South Africa and Abidjan, C??te d??Ivoire

article

Trends in Pretreatment HIV-1 Drug Resistance in Antiretroviral Therapy-naive Adults in South Africa, 2000-2016: A Pooled Sequence Analysis

article

UCLA1 aptamer inhibition of human immunodeficiency virus type 1 subtype C primary isolates in macrophages and selection of resistance

artículo científico publicado en 2016

UCLA1, a synthetic derivative of a gp120 RNA aptamer, inhibits entry of human immunodeficiency virus type 1 subtype C

artículo científico publicado en 2012

Use of a novel washing method combining multiple density gradients and trypsin for removing human immunodeficiency virus-1 and hepatitis C virus from semen

artículo científico publicado en 2005

Use of alternate coreceptors on primary cells by two HIV-1 isolates

artículo científico publicado en 2005

V2-Directed Vaccine-like Antibodies from HIV-1 Infection Identify an Additional K169-Binding Light Chain Motif with Broad ADCC Activity

article

Variable Dependence on Glycan Recognition within a Lineage of V1V2-directed HIV Neutralizing Antibodies.

artículo científico publicado en 2014

Viral dynamics and CD4+ T cell counts in subtype C human immunodeficiency virus type 1-infected individuals from southern Africa

artículo científico publicado en 2005

Viral escape from HIV-1 neutralizing antibodies drives increased plasma neutralization breadth through sequential recognition of multiple epitopes and immunotypes

artículo científico publicado en 2013

Viral suppression following switch to second-line antiretroviral therapy: associations with nucleoside reverse transcriptase inhibitor resistance and subtherapeutic drug concentrations prior to switch

scientific article published on 13 August 2013

Viral variants that initiate and drive maturation of V1V2-directed HIV-1 broadly neutralizing antibodies

artículo científico publicado en 2015

Viremia and drug resistance among HIV-1 patients on antiretroviral treatment: a cross-sectional study in Soweto, South Africa

artículo científico publicado en 2010

Viremia, resuppression, and time to resistance in human immunodeficiency virus (HIV) subtype C during first-line antiretroviral therapy in South Africa

artículo científico publicado en 2009

Virological features associated with the development of broadly neutralizing antibodies to HIV-1

artículo científico publicado en 2015

Women exposed to single-dose nevirapine in successive pregnancies: effectiveness and nonnucleoside reverse transcriptase inhibitor resistance

artículo científico publicado en 2009

World Health Organization/HIVResNet Drug Resistance Laboratory Strategy.

artículo científico publicado en 2008

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