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A transient inhibition of mitochondrial ATP synthesis by nitric oxide synthase activation triggered apoptosis in primary cortical neurons.

artículo científico publicado en 2001

APC/CCdh1-Rock2 pathway controls dendritic integrity and memory

artículo científico publicado en 2017

Adapting glycolysis to cancer cell proliferation: the MAPK pathway focuses on PFKFB3

artículo científico publicado el 15 de junio de 2013

Age dependent changes in the cerebrospinal fluid concentration of nitrite and nitrate

artículo científico publicado en 1996

Amyloid-ß promotes neurotoxicity by Cdk5-induced p53 stabilization

artículo científico publicado en 2018

Antioxidant and bioenergetic coupling between neurons and astrocytes.

artículo científico

Antioxidants, reactive oxygen and nitrogen species, gene induction and mitochondrial function.

artículo científico publicado en 2002

Astrocyte NMDA receptors' activity sustains neuronal survival through a Cdk5-Nrf2 pathway.

artículo científico publicado en 2015

Astrocytic mitochondrial ROS modulate brain metabolism and mouse behaviour

artículo científico publicado en 2019

Bilirubin selectively inhibits cytochrome c oxidase activity and induces apoptosis in immature cortical neurons: assessment of the protective effects of glycoursodeoxycholic acid.

artículo científico publicado en 2009

Bioenergetics and redox adaptations of astrocytes to neuronal activity.

artículo científico publicado en 2016

Brain energy metabolism in glutamate-receptor activation and excitotoxicity: role for APC/C-Cdh1 in the balance glycolysis/pentose phosphate pathway.

artículo científico

Cdh1/Hct1-APC is essential for the survival of postmitotic neurons.

artículo científico publicado en 2005

Cdk5 phosphorylates Cdh1 and modulates cyclin B1 stability in excitotoxicity

scientific journal article

Cdk5-mediated inhibition of APC/C-Cdh1 switches on the cyclin D1-Cdk4-pRb pathway causing aberrant S-phase entry of postmitotic neurons.

artículo científico publicado en 2015

Complex I assembly into supercomplexes determines differential mitochondrial ROS production in neurons and astrocytes.

artículo científico publicado en 2016

Current technical approaches to brain energy metabolism

artículo científico publicado en 2017

Cyclo(His-Pro) promotes cytoprotection by activating Nrf2-mediated up-regulation of antioxidant defence.

artículo científico publicado en 2008

D-Glucose prevents glutathione oxidation and mitochondrial damage after glutamate receptor stimulation in rat cortical primary neurons

artículo científico publicado en 2000

DJ1 represses glycolysis and cell proliferation by transcriptionally up-regulating Pink1.

artículo científico publicado en 2015

Depletion of brain glutathione results in a decrease of glutathione reductase activity; an enzyme susceptible to oxidative damage.

artículo científico publicado en 1996

Dichloroacetate prevents restenosis in preclinical animal models of vessel injury

artículo científico publicado en 2014

Different responses of astrocytes and neurons to nitric oxide: the role of glycolytically generated ATP in astrocyte protection.

artículo científico publicado en 2001

Does APC/CCDH1 control the human brain size?: An Editorial Highlight for 'A novel human Cdh1 mutation impairs anaphase-promoting complex/cyclosome (APC/C) activity resulting in microcephaly, psychomotor retardation, and epilepsy' on page 103

scientific article published on 23 August 2019

E3 ubiquitin ligase APC/C-Cdh1 accounts for the Warburg effect by linking glycolysis to cell proliferation

artículo científico publicado en 2009

Effect of hypoxia on urea synthesis in neonatal rat liver in vitro

artículo científico publicado en 1990

Effect of peroxynitrite on the mitochondrial respiratory chain: differential susceptibility of neurones and astrocytes in primary culture

scientific article published on 01 May 1995

Effect of valproate on lipogenesis in neonatal rat brain.

artículo científico publicado en 1993

Effect of valproate on the metabolism of the central nervous system.

artículo científico publicado en 1997

Erratum to: Inflammation, glucose, and vascular cell damage: the role of the pentose phosphate pathway.

artículo científico publicado en 2017

Essentiality of fatty acid synthase in the 2D to anchorage-independent growth transition in transforming cells

scientific article published on 01 November 2019

Evaluation of the efficacy of potential therapeutic agents at protecting against nitric oxide synthase-mediated mitochondrial damage in activated astrocytes

artículo científico publicado el 1 de agosto de 1997

Expression of glucose transporter GLUT3 by endotoxin in cultured rat astrocytes: the role of nitric oxide.

artículo científico publicado en 2001

Fgr kinase is required for proinflammatory macrophage activation during diet-induced obesity

scientific article published on 17 September 2020

Glucose metabolism links astroglial mitochondria to cannabinoid effects

scientific article published on 08 July 2020

Glutamate neurotoxicity is associated with nitric oxide-mediated mitochondrial dysfunction and glutathione depletion.

artículo científico publicado en 1998

Glutathione and γ-Glutamylcysteine in Hydrogen Peroxide Detoxification

artículo científico publicado el 1 de enero de 2013

Glutathione and γ-glutamylcysteine in the antioxidant and survival functions of mitochondria.

artículo científico

Glutathione depletion is accompanied by increased neuronal nitric oxide synthase activity

scientific article published on 01 January 1996

Glutathione protects astrocytes from peroxynitrite-mediated mitochondrial damage: implications for neuronal/astrocytic trafficking and neurodegeneration

scientific article published on 01 January 1996

Guidelines on experimental methods to assess mitochondrial dysfunction in cellular models of neurodegenerative diseases.

artículo científico publicado en 2017

Hippocampal neurons require a large pool of glutathione to sustain dendrite integrity and cognitive function

artículo científico publicado en 2018

Increased mitochondrial respiration maintains the mitochondrial membrane potential and promotes survival of cerebellar neurons in an endogenous model of glutamate receptor activation.

artículo científico publicado en 2005

Inflammation, glucose, and vascular cell damage: the role of the pentose phosphate pathway

artículo científico publicado en 2016

Inhibition of PTEN by peroxynitrite activates the phosphoinositide-3-kinase/Akt neuroprotective signaling pathway

scientific journal article

Inhibition of astrocyte gap junctional communication by ATP depletion is reversed by calcium sequestration

artículo científico publicado en 1996

Inhibition of mitochondrial respiration by nitric oxide rapidly stimulates cytoprotective GLUT3-mediated glucose uptake through 5'-AMP-activated protein kinase

scientific journal article

Inhibition of neonatal brain fuel utilization by valproate and E-delta 2-valproate is not a consequence of the stimulation of the gamma-aminobutyric acid shunt.

artículo científico publicado en 1994

Integrating Molecular Mechanisms with Synaptic Plasticity in Neurological Disease

artículo científico publicado el 26 de agosto de 2012

Interrelationships between astrocyte function, oxidative stress and antioxidant status within the central nervous system.

artículo científico publicado en 1997

Involvement of reactive oxygen species on gentamicin-induced mesangial cell activation.

artículo científico publicado en 2002

LRRK2 Expression Is Deregulated in Fibroblasts and Neurons from Parkinson Patients with Mutations in PINK1.

artículo científico publicado en 2016

Lactate utilization by neonatal rat liver in vitro

artículo científico publicado en 1990

Linking glycolysis with oxidative stress in neural cells: a regulatory role for nitric oxide.

artículo científico publicado en 2007

Lipogenesis from lactate in fetal rat brain during late gestation.

artículo científico publicado en 1993

Melatonin induces the expression of Nrf2-regulated antioxidant enzymes via PKC and Ca2+ influx activation in mouse pancreatic acinar cells.

artículo científico publicado en 2015

Mitochondria and reactive oxygen and nitrogen species in neurological disorders and stroke: Therapeutic implications.

artículo científico publicado en 2009

Mitochondrial Complex I Activity is Conditioned by Supercomplex I-III2-IV Assembly in Brain Cells: Relevance for Parkinson's Disease.

artículo científico publicado en 2017

Mitochondrial control of cell bioenergetics in Parkinson's disease.

artículo científico publicado en 2016

Mitochondrial damage: an important feature in a number of inborn errors of metabolism?

scientific article published on 01 January 1996

Mitochondrial respiratory chain and free radical generation in stroke.

artículo científico publicado en 2005

Mitochondrial respiratory chain disorganization in Parkinson's disease-relevant PINK1 and DJ1 mutants

artículo científico publicado en 2017

Modulation of astroglial energy metabolism by nitric oxide.

artículo científico publicado en 2006

NF-κB Activity Initiates Human ESC-Derived Neural Progenitor Cell Differentiation by Inducing a Metabolic Maturation Program.

artículo científico publicado en 2018

NRF2 Orchestrates the Metabolic Shift during Induced Pluripotent Stem Cell Reprogramming.

artículo científico publicado en 2016

Neovascularization and functional recovery after intracerebral hemorrhage is conditioned by the Tp53 Arg72Pro single-nucleotide polymorphism

artículo científico publicado en 2016

Nitric oxide mediates brain mitochondrial damage during perinatal anoxia.

artículo científico publicado en 1998

Nitric oxide mediates brain mitochondrial maturation immediately after birth.

artículo científico publicado en 1999

Nitric oxide produced by activated astrocytes rapidly and reversibly inhibits cellular respiration

scientific article published on 01 July 1995

Nitric oxide switches on glycolysis through the AMP protein kinase and 6-phosphofructo-2-kinase pathway.

artículo científico publicado en 2003

Nitric oxide, cell bioenergetics and neurodegeneration.

artículo científico publicado en 2006

Nitric oxide, energy metabolism and neurological disease.

artículo científico publicado en 1997

Nitric oxide-mediated mitochondrial damage: a potential neuroprotective role for glutathione

scientific article published on 01 January 1996

Nuclear WRAP53 promotes neuronal survival and functional recovery after stroke

artículo científico publicado en 2020

PINK1 deficiency sustains cell proliferation by reprogramming glucose metabolism through HIF1.

artículo científico publicado en 2014

Peroxiredoxin 5 links mitochondrial redox signalling with calcium dynamics: impact on Parkinson's disease

artículo científico publicado en 2013

Peroxynitrite anion stimulates arginine release from cultured rat astrocytes

scientific article published on 01 October 1999

Peroxynitrite protects neurons against nitric oxide-mediated apoptosis. A key role for glucose-6-phosphate dehydrogenase activity in neuroprotection

scientific journal article

Poly(ADP-ribose) polymerase-1 protects neurons against apoptosis induced by oxidative stress

scientific journal article

Potential mechanisms for nitric oxide-mediated impairment of brain mitochondrial energy metabolism.

artículo científico publicado en 1997

Provoking neuroprotection by peroxynitrite.

artículo científico publicado en 2004

Redox status and bioenergetics liaison in cancer and neurodegeneration.

artículo científico publicado en 2012

Regulation of BDNF Release by ARMS/Kidins220 through Modulation of Synaptotagmin-IV Levels

artículo científico publicado en 2018

Regulation of Bcl-xL-ATP Synthase Interaction by Mitochondrial Cyclin B1-Cyclin-Dependent Kinase-1 Determines Neuronal Survival

artículo científico publicado en 2015

Regulation of glucose metabolism by nitrosative stress in neural cells.

artículo científico publicado en 2004

Single-Nucleotide Polymorphism 309T>G in the MDM2 Promoter Determines Functional Outcome After Stroke

scientific article published on 01 October 2018

TIGAR's promiscuity

artículo científico publicado en 2014

Targeting PFKFB3 alleviates cerebral ischemia-reperfusion injury in mice

scientific article published on 12 August 2019

The assumption that nitric oxide inhibits mitochondrial ATP synthesis is correct.

artículo científico publicado en 1999

The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C-Cdh1.

artículo científico publicado en 2009

The human Tp53 Arg72Pro polymorphism explains different functional prognosis in stroke.

artículo científico publicado en 2011

The oxidized form of vitamin C, dehydroascorbic acid, regulates neuronal energy metabolism

artículo científico publicado en 2014

The pentose-phosphate pathway in neuronal survival against nitrosative stress.

artículo científico publicado en 2010

Trolox protects mitochondrial complex IV from nitric oxide-mediated damage in astrocytes

scientific article published on 01 December 1994

Uncertainties in pentose-phosphate pathway flux assessment underestimate its contribution to neuronal glucose consumption: relevance for neurodegeneration and aging

artículo científico publicado en 2015

Underestimation of the pentose-phosphate pathway in intact primary neurons as revealed by metabolic flux analysis.

artículo científico publicado en 2013

p38γ and p38δ regulate postnatal cardiac metabolism through glycogen synthase 1

artículo científico publicado en 2021

α-Ketoglutarate dehydrogenase complex moonlighting: ROS signalling added to the list: An Editorial highlight for 'Reductions in the mitochondrial enzyme α-ketoglutarate dehydrogenase complex in neurodegenerative disease - beneficial or detrimental?'

artículo científico publicado en 2016