Lista de obras -

A Plasmodium yoelii HECT-like E3 ubiquitin ligase regulates parasite growth and virulence

artículo científico publicado en 2017

A class of tricyclic compounds blocking malaria parasite oocyst development and transmission

artículo científico publicado en 2012

A platform of assays for the discovery of anti-Zika small-molecules with activity in a 3D-bioprinted outer-blood-retina model

artículo científico publicado en 2022

A single nucleotide polymorphism in the Plasmodium falciparum atg18 gene associates with artemisinin resistance and confers enhanced parasite survival under nutrient deprivation

article

A specific inhibitor of PfCDPK4 blocks malaria transmission: chemical-genetic validation.

artículo científico publicado en 2013

A systematic and prospectively validated approach for identifying synergistic drug combinations against malaria.

artículo científico publicado en 2018

Actinoramide A Identified as a Potent Antimalarial from Titration-Based Screening of Marine Natural Product Extracts ⬇️

artículo científico publicado en 2015

An OpenData portal to share COVID-19 drug repurposing data in real time

artículo científico publicado en 2020

Application of niclosamide and analogs as small molecule inhibitors of Zika virus and SARS-CoV-2 infection

artículo científico publicado en 2021

Artemisinin resistance phenotypes and K13 inheritance in a Plasmodium falciparum cross and Aotus model

scientific article published on 19 November 2018

Artemisinin-based combination therapies: a vital tool in efforts to eliminate malaria

artículo científico publicado en 2009

C-terminal proteolysis of prenylated proteins in trypanosomatids and RNA interference of enzymes required for the post-translational processing pathway of farnesylated proteins

artículo científico publicado en 2007

Canvass: A Crowd-Sourced, Natural Product Screening Library for Exploring Biological Space

Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space

Cloning and analysis of Trypanosoma cruzi lanosterol 14alpha-demethylase

artículo científico publicado en 2003

Cloning, heterologous expression, and substrate specificities of protein farnesyltransferases from Trypanosoma cruzi and Leishmania major

artículo científico publicado en 2002

Correction to Remdesivir: A Review of Its Discovery and Development Leading to Human Clinical Trials for Treatment of COVID-19

artículo científico publicado en 2020

Design and synthesis of peptidomimetic protein farnesyltransferase inhibitors as anti-Trypanosoma brucei agents.

artículo científico publicado en 2004

Discovery of Synergistic and Antagonistic Drug Combinations against SARS-CoV-2 In Vitro

artículo científico publicado en 2020

Drug Repurposing Screen for Compounds Inhibiting the Cytopathic Effect of SARS-CoV-2

artículo científico publicado en 2020

Drug Repurposing Screen for Compounds Inhibiting the Cytopathic Effect of SARS-CoV-2

artículo científico publicado en 2020

Ex vivo susceptibility of Plasmodium falciparum to antimalarial drugs in western, northern, and eastern Cambodia, 2011-2012: association with molecular markers

scientific article published on 12 August 2013

Genome-wide profiling of chromosome interactions in Plasmodium falciparum characterizes nuclear architecture and reconfigurations associated with antigenic variation

artículo científico publicado en 2013

High-throughput matrix screening identifies synergistic and antagonistic antimalarial drug combinations

artículo científico publicado en 2015

Leishmania inactivation in human pheresis platelets by a psoralen (amotosalen HCl) and long-wavelength ultraviolet irradiation.

artículo científico publicado en 2005

Mechanism of splenic cell death and host mortality in a Plasmodium yoelii malaria model

artículo científico publicado en 2017

Modulation of Triple Artemisinin-Based Combination Therapy Pharmacodynamics by <i>Plasmodium falciparum</i> Genotype

scientific article published on 02 November 2020

Oxidosqualene cyclase inhibitors as antimicrobial agents.

artículo científico publicado en 2003

PfCRT and PfMDR1 modulate interactions of artemisinin derivatives and ion channel blockers

artículo científico publicado en 2016

Piperaquine resistance is associated with a copy number variation on chromosome 5 in drug-pressured Plasmodium falciparum parasites

artículo científico publicado en 2011

Plasmodium vivax chloroquine resistance links to pvcrt transcription in a genetic cross

artículo científico publicado en 2019

Protein farnesyl and N-myristoyl transferases: piggy-back medicinal chemistry targets for the development of antitrypanosomatid and antimalarial therapeutics.

artículo científico publicado en 2003

Protein farnesyl transferase inhibitors for the treatment of malaria and African trypanosomiasis.

artículo científico publicado en 2005

Quantitative assessment of Plasmodium falciparum sexual development reveals potent transmission-blocking activity by methylene blue

artículo científico publicado en 2011

Recent highlights in antimalarial drug resistance and chemotherapy research

artículo científico publicado en 2008

Regulation of Plasmodium yoelii oocyst development by strain- and stage-specific small-subunit rRNA

artículo científico publicado en 2015

Remdesivir: A Review of Its Discovery and Development Leading to Emergency Use Authorization for Treatment of COVID-19

artículo científico publicado en 2020

Resistance mutations at the lipid substrate binding site of Plasmodium falciparum protein farnesyltransferase

artículo científico publicado en 2007

Resistance to a protein farnesyltransferase inhibitor in Plasmodium falciparum

artículo científico publicado en 2005

Supergenomic network compression and the discovery of EXP1 as a glutathione transferase inhibited by artesunate

artículo científico publicado en 2014

Synergistic and Antagonistic Drug Combinations against SARS-CoV-2

artículo científico publicado en 2020

Targeting ACE2-RBD Interaction as a Platform for COVID-19 Therapeutics: Development and Drug-Repurposing Screen of an AlphaLISA Proximity Assay

artículo científico publicado en 2020

Thematic review series: lipid posttranslational modifications. Fighting parasitic disease by blocking protein farnesylation

artículo científico publicado en 2006

Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors

artículo científico publicado en 2020

Trypanosoma cruzi inactivation in human platelet concentrates and plasma by a psoralen (amotosalen HCl) and long-wavelength UV.

artículo científico publicado en 2003

mQC: A Heuristic Quality-Control Metric for High-Throughput Drug Combination Screening.

artículo científico publicado en 2016

Lista de obras de

A Plasmodium yoelii HECT-like E3 ubiquitin ligase regulates parasite growth and virulence

A class of tricyclic compounds blocking malaria parasite oocyst development and transmission

A platform of assays for the discovery of anti-Zika small-molecules with activity in a 3D-bioprinted outer-blood-retina model

A single nucleotide polymorphism in the Plasmodium falciparum atg18 gene associates with artemisinin resistance and confers enhanced parasite survival under nutrient deprivation

A specific inhibitor of PfCDPK4 blocks malaria transmission: chemical-genetic validation.

A systematic and prospectively validated approach for identifying synergistic drug combinations against malaria.

Actinoramide A Identified as a Potent Antimalarial from Titration-Based Screening of Marine Natural Product Extracts ⬇️

An OpenData portal to share COVID-19 drug repurposing data in real time

Application of niclosamide and analogs as small molecule inhibitors of Zika virus and SARS-CoV-2 infection

Artemisinin resistance phenotypes and K13 inheritance in a Plasmodium falciparum cross and Aotus model

Artemisinin-based combination therapies: a vital tool in efforts to eliminate malaria

C-terminal proteolysis of prenylated proteins in trypanosomatids and RNA interference of enzymes required for the post-translational processing pathway of farnesylated proteins

Canvass: A Crowd-Sourced, Natural Product Screening Library for Exploring Biological Space

Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space

Cloning and analysis of Trypanosoma cruzi lanosterol 14alpha-demethylase

Cloning, heterologous expression, and substrate specificities of protein farnesyltransferases from Trypanosoma cruzi and Leishmania major

Correction to Remdesivir: A Review of Its Discovery and Development Leading to Human Clinical Trials for Treatment of COVID-19

Design and synthesis of peptidomimetic protein farnesyltransferase inhibitors as anti-Trypanosoma brucei agents.

Discovery of Synergistic and Antagonistic Drug Combinations against SARS-CoV-2 In Vitro

Drug Repurposing Screen for Compounds Inhibiting the Cytopathic Effect of SARS-CoV-2

Drug Repurposing Screen for Compounds Inhibiting the Cytopathic Effect of SARS-CoV-2

Ex vivo susceptibility of Plasmodium falciparum to antimalarial drugs in western, northern, and eastern Cambodia, 2011-2012: association with molecular markers

Genome-wide profiling of chromosome interactions in Plasmodium falciparum characterizes nuclear architecture and reconfigurations associated with antigenic variation

High-throughput matrix screening identifies synergistic and antagonistic antimalarial drug combinations

Leishmania inactivation in human pheresis platelets by a psoralen (amotosalen HCl) and long-wavelength ultraviolet irradiation.

Mechanism of splenic cell death and host mortality in a Plasmodium yoelii malaria model

Modulation of Triple Artemisinin-Based Combination Therapy Pharmacodynamics by <i>Plasmodium falciparum</i> Genotype

Oxidosqualene cyclase inhibitors as antimicrobial agents.

PfCRT and PfMDR1 modulate interactions of artemisinin derivatives and ion channel blockers

Piperaquine resistance is associated with a copy number variation on chromosome 5 in drug-pressured Plasmodium falciparum parasites

Plasmodium vivax chloroquine resistance links to pvcrt transcription in a genetic cross

Protein farnesyl and N-myristoyl transferases: piggy-back medicinal chemistry targets for the development of antitrypanosomatid and antimalarial therapeutics.

Protein farnesyl transferase inhibitors for the treatment of malaria and African trypanosomiasis.

Quantitative assessment of Plasmodium falciparum sexual development reveals potent transmission-blocking activity by methylene blue

Recent highlights in antimalarial drug resistance and chemotherapy research

Regulation of Plasmodium yoelii oocyst development by strain- and stage-specific small-subunit rRNA

Remdesivir: A Review of Its Discovery and Development Leading to Emergency Use Authorization for Treatment of COVID-19

Resistance mutations at the lipid substrate binding site of Plasmodium falciparum protein farnesyltransferase

Resistance to a protein farnesyltransferase inhibitor in Plasmodium falciparum

Supergenomic network compression and the discovery of EXP1 as a glutathione transferase inhibited by artesunate

Synergistic and Antagonistic Drug Combinations against SARS-CoV-2

Targeting ACE2-RBD Interaction as a Platform for COVID-19 Therapeutics: Development and Drug-Repurposing Screen of an AlphaLISA Proximity Assay

Thematic review series: lipid posttranslational modifications. Fighting parasitic disease by blocking protein farnesylation

Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors

Trypanosoma cruzi inactivation in human platelet concentrates and plasma by a psoralen (amotosalen HCl) and long-wavelength UV.

mQC: A Heuristic Quality-Control Metric for High-Throughput Drug Combination Screening.