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Lista de obras de Andrew B Tobin

6-Phenylpyrimidin-4-ones as Positive Allosteric Modulators at the M1 mAChR: The Determinants of Allosteric Activity

artículo científico publicado en 2018

Artemisinin-resistant K13 mutations rewire Plasmodium falciparum's intra-erythrocytic metabolic program to enhance survival

artículo científico publicado en 2021

Assessment of the molecular mechanisms of action of novel 4-phenylpyridine-2-one and 6-phenylpyrimidin-4-one allosteric modulators at the M1 muscarinic acetylcholine receptors

artículo científico publicado en 2018

Author Correction: Combinatorial expression of GPCR isoforms affects signalling and drug responses

scientific article published on 25 November 2020

Biased M1-muscarinic-receptor-mutant mice inform the design of next-generation drugs

artículo científico publicado en 2020

Bitopic Binding Mode of an M1 Muscarinic Acetylcholine Receptor Agonist Associated with Adverse Clinical Trial Outcomes.

artículo científico publicado en 2018

Chemogenetics defines receptor-mediated functions of short chain free fatty acids

artículo científico publicado en 2019

Combinatorial expression of GPCR isoforms affects signalling and drug responses

artículo científico publicado en 2020

Crystal structure of the M5 muscarinic acetylcholine receptor

scientific article published on 26 November 2019

Development of Potent PfCLK3 Inhibitors Based on TCMDC-135051 as a New Class of Antimalarials

artículo científico publicado en 2020

M1 muscarinic allosteric modulators slow prion neurodegeneration and restore memory loss

artículo científico publicado en 2016

Pathophysiological regulation of lung function by the free fatty acid receptor FFA4

artículo científico publicado en 2020

Restoring Agonist Function at a Chemogenetically Modified M1 Muscarinic Acetylcholine Receptor

artículo científico publicado en 2020

Stimulus bias provides evidence for conformational constraints in the structure of a G protein-coupled receptor

artículo científico publicado en 2012

Structure-Activity Relationship Studies of Tetrahydroquinolone Free Fatty Acid Receptor 3 Modulators

scientific article published on 19 March 2020

The M<sub>1</sub> muscarinic receptor is present in situ as a ligand-regulated mixture of monomers and oligomeric complexes

artículo científico publicado en 2022

Validation of the protein kinase PfCLK3 as a multistage cross-species malarial drug target

artículo científico publicado en 2019

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