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A 12-mer repetitive antigenic epitope from Trypanosoma cruzi is a potential marker of therapeutic efficacy in chronic Chagas' disease.

artículo científico publicado en 2016

A DEVH-box RNA Helicase from Leishmania braziliensis is Associated to mRNA Cytoplasmic Granules.

artículo científico publicado en 2015

A Parasite Biomarker Set for Evaluating Benznidazole Treatment Efficacy in Patients with Chronic Asymptomatic Trypanosoma cruzi Infection

artículo científico publicado en 2019

A head-to-tail tandem organization of hsp70 genes in Trypanosoma cruzi

artículo científico publicado en 1988

A potential Z-DNA-forming sequence is located between two transcription units alternatively expressed during development of Drosophila hydei

artículo científico publicado en 1991

A trial of the synthetic malaria vaccine SPf66 in Tanzania: rationale and design

artículo científico publicado en 1994

Activity of rhodium(III) complexes against Trypanosoma cruzi

artículo científico publicado en 1988

Altering the motility of Trypanosoma cruzi with rabbit polyclonal anti-peptide antibodies reduces infection to susceptible mammalian cells.

artículo científico publicado en 2015

An observational longitudinal study to evaluate tools and strategies available for the diagnosis of Congenital Chagas Disease in a non-endemic country

scientific article published on 05 August 2019

Antiparasitic Treatment Induces an Improved CD8+ T Cell Response in Chronic Chagasic Patients.

artículo científico publicado en 2017

Antitrypanosomal action of cis-diamminedichloroplatinum (II) analogs

article published in 1987

Benznidazole treatment reduces the induction of indoleamine 2,3-dioxygenase (IDO) enzymatic activity in Chagas disease symptomatic patients

artículo científico publicado en 2013

Biological markers for evaluating therapeutic efficacy in Chagas disease, a systematic review.

artículo científico

Biology of Trypanosoma cruzi Retrotransposons: From an Enzymatic to a Structural Point of View.

artículo científico publicado en 2018

Biomarkers of therapeutic responses in chronic Chagas disease: state of the art and future perspectives

artículo científico publicado en 2015

Breaking the non-responsiveness of C57BL/6 mice to the malarial antigen EB200--the role of carrier and adjuvant molecules

artículo científico publicado en 2003

Calcium-induced conformational changes in Leishmania infantum kinetoplastid membrane protein-11.

artículo científico publicado en 2001

Cellular Location of KMP-11 Protein in Trypanosoma rangeli

scientific article published on 01 January 2008

Chagasic patients are able to respond against a viral antigen from influenza virus.

artículo científico publicado en 2012

Changes in saliva of dogs with canine leishmaniosis: A proteomic approach

artículo científico publicado en 2019

Characterising the KMP-11 and HSP-70 recombinant antigens' humoral immune response profile in chagasic patients.

artículo científico publicado en 2009

Characterization of SPf(66)n: a chimeric molecule used as a malaria vaccine.

artículo científico publicado en 1994

Characterization of a highly repeated interspersed DNA sequence of Trypanosoma cruzi: its potential use in diagnosis and strain classification

artículo científico publicado en 1992

Characterization of a non-long terminal repeat retrotransposon cDNA (L1Tc) from Trypanosoma cruzi: homology of the first ORF with the ape family of DNA repair enzymes.

artículo científico publicado en 1995

Characterization of a short interspersed reiterated DNA sequence of Trypanosoma cruzi located at the 3'-end of a poly(A)+ transcript.

artículo científico publicado en 1994

Characterization of an immunodominant antigenic epitope from Trypanosoma cruzi as a biomarker of chronic Chagas' disease pathology.

artículo científico publicado en 2011

Characterization of reverse transcriptase activity of the L1Tc retroelement from Trypanosoma cruzi

artículo científico publicado en 2003

Control mechanisms of the H2A genes expression in Trypanosoma cruzi

artículo científico publicado en 1998

Cytoplasmic-nuclear translocation of the Hsp70 protein during environmental stress in Trypanosoma cruzi

artículo científico publicado en 1993

DNA binding properties and antileukemic (L1210) activity of a Pt-pentamidine complex

artículo científico publicado en 1991

DNA immunization with Trypanosoma cruzi HSP70 fused to the KMP11 protein elicits a cytotoxic and humoral immune response against the antigen and leads to protection.

artículo científico publicado en 2001

Dataset for distribution of SIDER2 elements in the Leishmania major genome and transcriptome.

artículo científico publicado en 2017

Diagnosis of infections with Leishmania infantum using PCR-ELISA

scientific article published on 01 June 2001

Differential CD86 and CD40 co-stimulatory molecules and cytokine expression pattern induced by Trypanosoma cruzi in APCs from resistant or susceptible mice

artículo científico publicado en 2003

Differential phenotypic and functional profiles of TcCA-2 -specific cytotoxic CD8+ T cells in the asymptomatic versus cardiac phase in Chagasic patients.

artículo científico publicado en 2015

Do non-long terminal repeat retrotransposons have nuclease activity?

artículo científico publicado en 1996

Dynamics of T cells repertoire during Trypanosoma cruzi infection and its post-treatment modulation

article

Effect of secondary anchor amino acid substitutions on the immunogenic properties of an HLA-A*0201-restricted T cell epitope derived from the Trypanosoma cruzi KMP-11 protein

artículo científico publicado en 2016

Effect of storage on acetylcholinesterase activity

scientific article published on 01 February 1986

Evaluating Chagas disease progression and cure through blood-derived biomarkers: a systematic review

artículo científico publicado en 2013

Evaluation of IFN-gamma production by CD8+ T lymphocytes in response to the K1 peptide from KMP-11 protein in patients infected with Trypanosoma cruzi

article

Expression of inhibitory receptors and polyfunctional responses of T cells are linked to the risk of congenital transmission of T. cruzi

artículo científico publicado en 2017

Frequency of specific CD8+ T cells for a promiscuous epitope derived from Trypanosoma cruzi KMP-11 protein in chagasic patients

artículo científico publicado en 2010

Genomic cartography and proposal of nomenclature for the repeated, interspersed elements of the Leishmania major SIDER2 family and identification of SIDER2-containing transcripts.

artículo científico publicado en 2016

Genomic clustering of the Trypanosoma cruzi nonlong terminal L1Tc retrotransposon with defined interspersed repeated DNA elements

artículo científico publicado en 2000

Genomic repetitive DNA elements of Trypanosoma cruzi

artículo científico publicado en 1996

HSP70 from Trypanosoma cruzi is endowed with specific cell proliferation potential leading to apoptosis

scientific article published on 01 December 2000

Identification of HLA-A∗02:01-restricted CTL epitopes in Trypanosoma cruzi heat shock protein-70 recognized by Chagas disease patients.

artículo científico publicado en 2011

Identification of a Trypanosoma cruzi antigenic epitope implicated in the infectivity of fibroblast LLC-MK2 cells.

artículo científico publicado en 1997

Identification of a type I nitroreductase gene in non-virulent Trypanosoma rangeli.

artículo científico publicado en 2017

Identification of an hepatitis delta virus-like ribozyme at the mRNA 5'-end of the L1Tc retrotransposon from Trypanosoma cruzi

artículo científico publicado en 2011

Identification of non-autonomous non-LTR retrotransposons in the genome of Trypanosoma cruzi

artículo científico publicado en 2002

Immune responses to Plasmodium falciparum antigens during a malaria vaccine trial in Tanzanian children

artículo científico publicado en 1998

Immunogenicity of HSP-70, KMP-11 and PFR-2 leishmanial antigens in the experimental model of canine visceral leishmaniasis

article

Immunological and structural characterization of an epitope from the Trypanosoma cruzi KMP-11 protein

article

Impact of benznidazole treatment on the functional response of Trypanosoma cruzi antigen-specific CD4+CD8+ T cells in chronic Chagas disease patients.

artículo científico publicado en 2018

Inhibitory Receptor Expression on CD8+ T Cells Is Linked to Functional Responses against Trypanosoma cruzi Antigens in Chronic Chagasic Patients.

artículo científico publicado en 2015

Isolation and characterization of the gene encoding histone H2A from Trypanosoma cruzi

artículo científico publicado en 1994

L1Tc non-LTR retrotransposons from Trypanosoma cruzi contain a functional viral-like self-cleaving 2A sequence in frame with the active proteins they encode

artículo científico publicado en 2006

Label-free quantitative proteomic analysis reveals potential biomarkers for early healing in cutaneous leishmaniasis

artículo científico publicado en 2019

Locations of Z-DNA in polytene chromosomes.

artículo científico publicado en 1985

Longitudinal monitoring of anti-saliva antibodies as markers of repellent efficacy against Phlebotomus perniciosus and Phlebotomus papatasi in dogs

scientific article published on 18 November 2018

Mapping of the antigenic determinants of the T. cruzi kinetoplastid membrane protein-11. Identification of a linear epitope specifically recognized by human Chagasic sera

artículo científico publicado en 2001

Microbial heat shock protein 70 stimulatory properties have different TLR requirements

artículo científico publicado en 2006

Mode of action of intercalating drug, cis-Pt(II)(DDH)Cl2, cis-Pt(II)(DDH) (metafluorobenzoic)2, and cis-Pt(II)(DDH)(mucubromic)2, on Trypanosoma cruzi

scientific article published on 01 March 1987

Molecular and immunological characterization of L14 ribosomal protein from Leishmania braziliensis.

artículo científico publicado en 2004

Molecular characterization of KMP11 from Trypanosoma cruzi: a cytoskeleton-associated protein regulated at the translational level

artículo científico publicado en 2000

Molecular characterization of calcineurin B from the non-virulent Trypanosoma rangeli kinetoplastid indicates high gene conservation

artículo científico

Molecular characterization of the histone H2A gene from the parasite Trypanosoma rangeli.

artículo científico publicado en 2000

Molecular characterization of the kinetoplastid membrane protein-11 genes from the parasite Trypanosoma rangeli

artículo científico publicado en 2005

Molecular characterization of the short interspersed repetitive element SIRE in the six discrete typing units (DTUs) of Trypanosoma cruzi.

artículo científico publicado en 2012

Molecular cloning of a Drosophila potential Z-DNA forming sequence hybridizing in situ to a developmentally regulated subdivision of the polytene chromosomes

artículo científico publicado en 1989

Monocyte-derived dendritic cells from chagasic patients vs healthy donors secrete differential levels of IL-10 and IL-12 when stimulated with a protein fragment of Trypanosoma cruzi heat-shock protein-70

artículo científico publicado en 2008

Multiprimer PCR system for differential identification of mycobacteria in clinical samples.

artículo científico publicado en 1996

Natural CD4+ T-cell responses against Trypanosoma cruzi KMP-11 protein in chronic chagasic patients

scientific article published on 28 October 2008

Nucleic-acid-binding properties of the C2-L1Tc nucleic acid chaperone encoded by L1Tc retrotransposon

artículo científico publicado en 2009

One-year follow-up of anti-Leishmania antibody concentrations in serum and saliva from experimentally infected dogs

artículo científico publicado en 2019

Oral transmission of Chagas disease: typing of Trypanosoma cruzi from five outbreaks occurred in Venezuela shows multiclonal and common infections in patients, vectors and reservoirs

artículo científico publicado en 2013

Performance of Leishmania PFR1 recombinant antigen in serological diagnosis of asymptomatic canine leishmaniosis by ELISA

artículo científico publicado en 2017

Phage recovery by electroporation of naked DNA into host cells avoids the use of packaging extracts.

artículo científico publicado en 1999

Phenotypic and Functional Profiles of Antigen-Specific CD4 and CD8 T Cells Associated With Infection Control in Patients With Cutaneous Leishmaniasis

scientific article published on 19 November 2018

Plasticity of the histone H2A genes in a Brazilian and six Colombian strains of Trypanosoma cruzi.

artículo científico publicado en 2000

Pr77 and L1TcRz

artículo científico publicado en 2012

Promiscuous Recognition of a Trypanosoma cruzi CD8+ T Cell Epitope among HLA-A2, HLA-A24 and HLA-A1 Supertypes in Chagasic Patients.

artículo científico publicado en 2016

Rabbit serum against K1 peptide, an immunogenic epitope of the Trypanosoma cruzi KMP-11, decreases parasite invasion to cells

scientific article published on 08 June 2012

Randomised trial of efficacy of SPf66 vaccine against Plasmodium falciparum malaria in children in southern Tanzania.

artículo científico publicado en 1994

Regulation of hsp70 expression in Trypanosoma cruzi by temperature and growth phase

artículo científico publicado en 1992

Reverse transcriptase-like activity in Trypanosoma cruzi

scientific article published on 01 February 1997

Risk factors and primary prevention of congenital Chagas disease in a nonendemic country.

artículo científico publicado en 2012

SPf66, a chemically synthesized subunit malaria vaccine, is safe and immunogenic in Tanzanians exposed to intense malaria transmission

artículo científico publicado en 1994

Sensitive detection of cereal fractions that are toxic to celiac disease patients by using monoclonal antibodies to a main immunogenic wheat peptide

artículo científico publicado en 2008

Sequence and expression of the Drosophila phenylalanine hydroxylase mRNA.

artículo científico publicado en 1990

Sequence polymorphism in the Trypanosoma rangeli HSP70 coding genes allows typing of the parasite KP1(+) and KP1(−) groups

artículo científico publicado en 2013

Serum proteome of dogs at subclinical and clinical onset of canine leishmaniosis

artículo científico publicado en 2019

Short-term follow-up of chagasic patients after benzonidazole treatment using multiple serological markers.

artículo científico publicado en 2011

Studies on the interaction between antitrypanosome cis-DDP analogs with dna

scientific article published on 01 July 1986

The L1Tc C-terminal domain from Trypanosoma cruzi non-long terminal repeat retrotransposon codes for a protein that bears two C2H2 zinc finger motifs and is endowed with nucleic acid chaperone activity.

artículo científico publicado en 2005

The L1Tc non-LTR retrotransposon of Trypanosoma cruzi contains an internal RNA-pol II-dependent promoter that strongly activates gene transcription and generates unspliced transcripts.

artículo científico publicado en 2007

The L1Tc, long interspersed nucleotide element from Trypanosoma cruzi, encodes a protein with 3'-phosphatase and 3'-phosphodiesterase enzymatic activities

artículo científico publicado en 1999

The SIDER2 elements, interspersed repeated sequences that populate the Leishmania genomes, constitute subfamilies showing chromosomal proximity relationship

artículo científico publicado en 2008

The Trypanosoma rangeli histone H2A gene sequence serves as a differential marker for KP1 strains

artículo científico publicado en 2006

The Trypanosomatid Pr77-hallmark contains a downstream core promoter element essential for transcription activity of the Trypanosoma cruzi L1Tc retrotransposon.

artículo científico publicado en 2016

The anti Z-DNA reactivity of Z-DNA forming sequences is affected by platinum antitumor drugs.

artículo científico publicado en 1993

The biology and evolution of transposable elements in parasites

artículo científico publicado en 2010

The effect of temperature on the stability of the synthetic SPf(66)n malaria vaccine.

artículo científico publicado en 1995

The endonuclease NL1Tc encoded by the LINE L1Tc from Trypanosoma cruzi protects parasites from daunorubicin DNA damage.

artículo científico publicado en 2003

The genetic immunization with paraflagellar rod protein-2 fused to the HSP70 confers protection against late Trypanosoma cruzi infection

artículo científico publicado en 2006

The heat shock protein hsp70 binds in vivo to subregions 2-48BC and 3-58D of the polytene chromosomes of Drosophila hydei

artículo científico publicado en 1990

The immunization of A2/K(b) transgenic mice with the KMP11-HSP70 fusion protein induces CTL response against human cells expressing the T. cruzi KMP11 antigen: identification of A2-restricted epitopes

scientific article published on 01 August 2001

The innate immune response status correlates with a divergent clinical course in congenital Chagas disease of twins born in a non-endemic country.

artículo científico publicado en 2014

The non-LTR (long terminal repeat) retrotransposon L1Tc from Trypanosoma cruzi codes for a protein with RNase H activity.

artículo científico publicado en 2002

The open reading frame 1 of the L1Tc retrotransposon of Trypanosoma cruzi codes for a protein with apurinic-apyrimidinic nuclease activity

artículo científico publicado en 1997

The stability and maturation of the H2A histone mRNAs from Trypanosoma cruzi are implicated in their post-transcriptional regulation

scientific article published on 01 January 2000

The wide expansion of hepatitis delta virus-like ribozymes throughout trypanosomatid genomes is linked to the spreading of L1Tc/ingi clade mobile elements.

artículo científico publicado en 2014

Toward the assessment of food toxicity for celiac patients: characterization of monoclonal antibodies to a main immunogenic gluten peptide.

artículo científico publicado en 2008

Towards a paradigm shift in the treatment of chronic Chagas disease.

artículo científico publicado en 2013

Towards the physical map of the Trypanosoma cruzi nuclear genome: construction of YAC and BAC libraries of the reference clone T. cruzi CL-Brener

artículo científico publicado en 1997

Transcriptional Profiling of Immune-Related Genes in Leishmania infantum-Infected Mice: Identification of Potential Biomarkers of Infection and Progression of Disease.

artículo científico publicado en 2018

Trypanosoma cruzi genotyping supports a common source of infection in a school-related oral outbreak of acute Chagas disease in Venezuela.

artículo científico publicado en 2013

Trypanosoma cruzi heat-shock protein-70 kDa,alone or fused to the parasite KMP11 antigen, induces functional maturation of murine dendritic cells

scientific article published on 01 June 2002

Trypanosoma cruzi paraflagellar rod proteins 2 and 3 contain immunodominant CD8(+) T-cell epitopes that are recognized by cytotoxic T cells from Chagas disease patients.

artículo científico publicado en 2012

Z-DNA in transcriptionally active chromosomes

artículo científico publicado en 1987

[Chromosomal localization of the KMP-11 genes in the KP1(+) and KP1(-) strains of Trypanosoma rangeli]

scientific article published on 01 June 2004

[Expression of markers on dendritic cells from chronic chagasic patients stimulated with the KMP-11 protein and the K1 peptide from Trypanosoma cruzi]

scientific article published on 01 January 2007

cis-Dichloro(alpha,omega-diamino carboxylate ethyl ester)palladium(II) as Palladium(II) versus Platinum(II) Model Anticancer Drugs: Synthesis, Solution Equilibria of Their Aqua, Hydroxo, and/or Chloro Species, and in Vitro/in Vivo DNA-Binding Proper

artículo científico publicado en 1997

Secuencia de nucleótidos del gen hsp70 de Trypanosoma cruzi

artículo científico publicado en 1989