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Antifungal synergy of a topical triazole, PC945, with a systemic triazole against respiratory Aspergillus fumigatus infection

scientific article published on 01 July 2019

Current approaches to the discovery of novel inhaled medicines

scientific article published on 20 May 2018

Discovery of Narrow Spectrum Kinase Inhibitors: New Therapeutic Agents for the Treatment of COPD and Steroid-Resistant Asthma.

artículo científico publicado en 2016

Discovery of novel benzothienoazepine derivatives as potent inhibitors of respiratory syncytial virus

artículo científico publicado en 2017

Effects of intranasally dosed posaconazole on fungal load and biomarkers in Aspergillus fumigatus infected immunocompromised mice.

artículo científico publicado en 2017

In Vitro and In Vivo Antifungal Profile of a Novel and Long-Acting Inhaled Azole, PC945, on Aspergillus fumigatus Infection

artículo científico publicado en 2017

In Vitro and In Vivo Efficacy of a Novel and Long Acting Fungicidal Azole, PC1244 on Aspergillus fumigatus Infection.

artículo científico publicado en 2018

In Vivo Biomarker Analysis of the Effects of Intranasally Dosed PC945, a Novel Antifungal Triazole, on Aspergillus fumigatus Infection in Immunocompromised Mice

artículo científico publicado en 2017

In vitro antifungal activity of a novel topical triazole PC945 against emerging yeast Candida auris

artículo científico publicado en 2019

Late therapeutic intervention with a respiratory syncytial virus L-protein polymerase inhibitor, PC786, on respiratory syncytial virus infection in human airway epithelium.

artículo científico publicado en 2018

Nasosorption as a Minimally Invasive Sampling Procedure: Mucosal Viral Load and Inflammation in Primary RSV Bronchiolitis.

artículo científico publicado en 2017

Neuropharmacology of emesis induced by anti-cancer therapy.

artículo científico publicado en 1988

Pharmacokinetics and anti-emetic efficacy of BRL43694, a new selective 5HT-3 antagonist.

artículo científico publicado en 1988

Plasma protein-binding and CSF concentrations of valproic acid in man following acute oral dosing.

artículo científico publicado en 1983

Preclinical Characterization of PC786, an Inhaled Small-Molecule Respiratory Syncytial Virus L Protein Polymerase Inhibitor

artículo científico publicado en 2017

Reduced Nasal Viral Load and IFN Responses in Infants with Respiratory Syncytial Virus Bronchiolitis and Respiratory Failure.

artículo científico publicado en 2018

Safety, tolerability and viral kinetics during SARS-CoV-2 human challenge in young adults

artículo científico publicado en 2022

The effects of serum, lithium, ethacrynic acid, and a low external concentration of potassium on specific [3H]-ouabain binding to human lymphocytes after incubation for 3 days.

artículo científico publicado en 1986

The influence of diet upon liver function tests and serum lipids in healthy male volunteers resident in a Phase I unit.

artículo científico publicado en 2004

The role of antifungals in the management of patients with severe asthma

artículo científico publicado en 2020

Variability of phenytoin protein binding in epilepsy

scientific article published on 01 April 1984