Lista de obras -

A Role for PPARbeta/delta in Tumor Stroma and Tumorigenesis.

artículo científico publicado en 2008

A species difference in the peroxisome proliferator-activated receptor α-dependent response to the developmental effects of perfluorooctanoic acid.

artículo científico publicado en 2012

Activation of peroxisome proliferator-activated receptor-β/δ (PPAR-β/δ) inhibits human breast cancer cell line tumorigenicity.

artículo científico publicado en 2014

Adaptive increase in pyruvate dehydrogenase kinase 4 during starvation is mediated by peroxisome proliferator-activated receptor alpha.

artículo científico publicado en 2001

Aryl hydrocarbon receptor antagonism attenuates growth factor expression, proliferation, and migration in fibroblast-like synoviocytes from patients with rheumatoid arthritis

artículo científico publicado en 2013

CYP2E1 is not involved in early alcohol-induced liver injury

scientific article published on 01 December 1999

Chemoprevention of chemically induced skin tumorigenesis by ligand activation of peroxisome proliferator-activated receptor-beta/delta and inhibition of cyclooxygenase 2.

artículo científico publicado en 2010

Cholestasis induces reversible accumulation of periplakin in mouse liver.

artículo científico publicado en 2013

Comparative in vivo and in vitro analysis of possible estrogenic effects of perfluorooctanoic acid

artículo científico publicado en 2014

Di(2-ethylhexyl) phthalate induces a functional zinc deficiency during pregnancy and teratogenesis that is independent of peroxisome proliferator-activated receptor-alpha

Scientific article

Differential hepatic effects of perfluorobutyrate mediated by mouse and human PPAR-alpha.

artículo científico publicado en 2009

Dissecting the role of peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) in colon, breast, and lung carcinogenesis.

artículo científico publicado en 2011

Editor's Highlight: PPARβ/δ and PPARγ Inhibit Melanoma Tumorigenicity by Modulating Inflammation and Apoptosis.

artículo científico publicado en 2017

Editor's Highlight: Perfluorooctane Sulfonate-Choline Ion Pair Formation: A Potential Mechanism Modulating Hepatic Steatosis and Oxidative Stress in Mice

artículo científico publicado en 2016

Effect of ligand activation of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) in human lung cancer cell lines

artículo científico publicado en 2008

Effect of prenatal peroxisome proliferator-activated receptor alpha (PPARalpha) agonism on postnatal development.

artículo científico publicado en 2010

Establishing the Role of PPARβ/δ in Carcinogenesis

artículo científico publicado en 2015

Etomoxir-induced PPARalpha-modulated enzymes protect during acute renal failure

scientific article published on 01 April 2000

Evidence that ligand binding is a key determinant of Ah receptor-mediated transcriptional activity.

artículo científico publicado en 2005

Flipping a citrate switch on liver cancer cells

artículo científico publicado en 2017

Four-week dietary supplementation with 10- and/or 15-fold basal choline caused decreased body weight in Sprague Dawley rats

artículo científico publicado en 2017

Functional characterization of peroxisome proliferator‐activated receptor‐β/δ expression in colon cancer ⬇️

artículo científico publicado el 11 de marzo de 2011

Immunomodulatory action of dietary fish oil and targeted deletion of intestinal epithelial cell PPARδ in inflammation-induced colon carcinogenesis ⬇️

artículo científico publicado el 22 de septiembre de 2011

Influence of peroxisome proliferator-activated receptor alpha on ubiquinone biosynthesis

artículo científico publicado en 2000

Inhibition of testicular embryonal carcinoma cell tumorigenicity by peroxisome proliferator-activated receptor-β/δ- and retinoic acid receptor-dependent mechanisms

artículo científico publicado en 2015

Inhibition of tumorigenesis by peroxisome proliferator-activated receptor (PPAR)-dependent cell cycle blocks in human skin carcinoma cells

artículo científico publicado en 2018

Interplay Between the Host, the Human Microbiome, and Drug Metabolism.

artículo científico publicado en 2019

Isolation, Characterization, and Purification of Macrophages from Tissues Affected by Obesity-related Inflammation.

artículo científico publicado en 2017

Ligand activation of peroxisome proliferator-activated receptor beta inhibits colon carcinogenesis.

artículo científico publicado en 2006

Ligand activation of peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta) attenuates carbon tetrachloride hepatotoxicity by downregulating proinflammatory gene expression

artículo científico publicado en 2008

Ligand activation of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) and inhibition of cyclooxygenase 2 (COX2) attenuate colon carcinogenesis through independent signaling mechanisms.

artículo científico publicado en 2007

Ligand activation of peroxisome proliferator-activated receptor-beta/delta inhibits cell proliferation in human HaCaT keratinocytes.

artículo científico publicado en 2008

Ligand activation of peroxisome proliferator-activated receptor-β/δ suppresses liver tumorigenesis in hepatitis B transgenic mice

artículo científico publicado en 2016

Lipid metabolism and lipophagy in cancer.

artículo científico publicado en 2018

M-CSF from Cancer Cells Induces Fatty Acid Synthase and PPARβ/δ Activation in Tumor Myeloid Cells, Leading to Tumor Progression

artículo científico publicado en 2015

Mode of action framework analysis for receptor-mediated toxicity: The peroxisome proliferator-activated receptor alpha (PPARα) as a case study.

artículo científico publicado en 2013

Modes of action and species-specific effects of di-(2-ethylhexyl)phthalate in the liver.

artículo científico publicado en 2006

Modulation of aryl hydrocarbon receptor (AHR)-dependent signaling by peroxisome proliferator-activated receptor β/δ (PPARβ/δ) in keratinocytes

artículo científico publicado en 2014

Modulation of gastrointestinal inflammation and colorectal tumorigenesis by peroxisome proliferator-activated receptor-β/δ (PPARβ/δ)

artículo científico publicado en 2011

Molecular Regulation of Carcinogenesis: Friend and Foe

artículo científico publicado en 2018

NTP-CERHR expert panel report on the developmental toxicity of soy infant formula.

artículo científico

Nrf2- and PPAR alpha-mediated regulation of hepatic Mrp transporters after exposure to perfluorooctanoic acid and perfluorodecanoic acid.

artículo científico publicado en 2008

Omics Approaches To Probe Microbiota and Drug Metabolism Interactions.

artículo científico publicado en 2016

PPAR action in insulin resistance unraveled by metabolomics: potential clinical implications

artículo científico publicado en 2011

PPAR alpha mediates peroxisome proliferator-induced transcriptional repression of nonperoxisomal gene expression in mouse

artículo científico publicado en 1997

PPARalpha and effects of TCE.

artículo científico publicado en 2007

PPARbeta/delta protects against experimental colitis through a ligand-independent mechanism.

artículo científico publicado en 2007

PPARdelta is pro-tumorigenic in a mouse model of COX-2-induced mammary cancer.

artículo científico publicado en 2008

PPARdelta status and mismatch repair mediated neoplasia in the mouse intestine.

artículo científico publicado en 2006

PPARgamma influences susceptibility to DMBA-induced mammary, ovarian and skin carcinogenesis.

artículo científico publicado en 2004

PPARβ/δ modulates ethanol-induced hepatic effects by decreasing pyridoxal kinase activity.

artículo científico publicado en 2013

PPARβ/δ promotes HRAS-induced senescence and tumor suppression by potentiating p-ERK and repressing p-AKT signaling

artículo científico publicado en 2013

PPARβ/δ selectively regulates phenotypic features of age-related macular degeneration.

scientific article published on 08 September 2016

Perfluorooctane Sulfonate-Induced Hepatic Steatosis in Male Sprague Dawley Rats Is Not Attenuated by Dietary Choline Supplementation.

artículo científico publicado en 2017

Peroxisome Proliferator-activated Receptor-D (PPARD) Coordinates Mouse Spermatogenesis by Modulating Extracellular Signal-regulated Kinase (ERK)-dependent Signaling.

artículo científico publicado en 2015

Peroxisome proliferator-activated receptor alpha mediates the adaptive response to fasting

artículo científico publicado en 1999

Peroxisome proliferator-activated receptor beta (delta)-dependent regulation of ubiquitin C expression contributes to attenuation of skin carcinogenesis.

artículo científico publicado en 2004

Peroxisome proliferator-activated receptor beta/delta regulates very low density lipoprotein production and catabolism in mice on a Western diet.

artículo científico publicado en 2004

Peroxisome proliferator-activated receptor β/δ cross talks with E2F and attenuates mitosis in HRAS-expressing cells.

artículo científico publicado en 2012

Peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) ligands inhibit growth of UACC903 and MCF7 human cancer cell lines.

artículo científico publicado en 2007

Peroxisome proliferator-activated receptor-delta agonist enhances vasculogenesis by regulating endothelial progenitor cells through genomic and nongenomic activations of the phosphatidylinositol 3-kinase/Akt pathway.

artículo científico publicado en 2008

Peroxisome proliferator-activated receptor-delta attenuates colon carcinogenesis.

artículo científico publicado en 2004

Peroxisome proliferator-activated receptor-β/δ inhibits human neuroblastoma cell tumorigenesis by inducing p53- and SOX2-mediated cell differentiation.

artículo científico publicado en 2016

Peroxisome proliferator-activated receptor-β/δ modulates mast cell phenotype.

artículo científico publicado en 2016

Pretreatment with troglitazone decreases lethality during endotoxemia in mice.

artículo científico publicado en 2002

Quantitative expression patterns of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) protein in mice

artículo científico publicado en 2008

Receptor and nonreceptor-mediated organ-specific toxicity of di(2-ethylhexyl)phthalate (DEHP) in peroxisome proliferator-activated receptor alpha-null mice

scientific article published on 01 March 1998

Reduced adiposity and liver steatosis by stearoyl-CoA desaturase deficiency are independent of peroxisome proliferator-activated receptor-alpha.

artículo científico publicado en 2004

Regulation of Cytochrome P450 2B10 (CYP2B10) Expression in Liver by Peroxisome Proliferator-activated Receptor-β/δ Modulation of SP1 Promoter Occupancy.

artículo científico publicado en 2016

Regulation of peroxisome proliferator-activated receptor-alpha by MDM2.

artículo científico publicado en 2008

Regulation of peroxisome proliferator-activated receptor-beta/delta by the APC/beta-CATENIN pathway and nonsteroidal antiinflammatory drugs.

artículo científico publicado en 2009

Regulatory mechanisms mediated by peroxisome proliferator-activated receptor-β/δ in skin cancer

artículo científico publicado en 2019

Sorting out the functional role(s) of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) in cell proliferation and cancer.

artículo científico publicado en 2009

Stable over-expression of PPARβ/δ and PPARγ to examine receptor signaling in human HaCaT keratinocytes

artículo científico publicado en 2011

Synthesis of isosteric selenium analog of the PPARbeta/delta agonist GW501516 and comparison of biological activity.

artículo científico publicado en 2010

Targeting Peroxisome Proliferator-Activated Receptor-β/δ (PPARβ/δ) for Cancer Chemoprevention.

artículo científico publicado en 2015

Targeting estrogen receptor-β for the prevention of nonmelanoma skin cancer

artículo científico publicado en 2014

The Evolution of Carcinogenesis

artículo científico publicado en 2018

The PPARalpha-leukotriene B4 pathway to inflammation control.

artículo científico publicado en 1996

The PPARα-dependent rodent liver tumor response is not relevant to humans: addressing misconceptions.

artículo científico publicado en 2017

The Ron Receptor Tyrosine Kinase Regulates Macrophage Heterogeneity and Plays a Protective Role in Diet-Induced Obesity, Atherosclerosis, and Hepatosteatosis.

artículo científico publicado en 2016

The aryl hydrocarbon receptor directly regulates expression of the potent mitogen epiregulin.

artículo científico publicado en 2005

The effect of valproic acid on 65Zn distribution in the pregnant rat.

artículo científico publicado en 1989

The nuclear receptor peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) promotes oncogene-induced cellular senescence through repression of endoplasmic reticulum stress.

artículo científico publicado en 2014

The role of peroxisome proliferator-activated receptors in carcinogenesis and chemoprevention

artículo científico publicado en 2012

Why toxic equivalency factors are not suitable for perfluoroalkyl chemicals

artículo científico

Lista de obras de

A Role for PPARbeta/delta in Tumor Stroma and Tumorigenesis.

A species difference in the peroxisome proliferator-activated receptor α-dependent response to the developmental effects of perfluorooctanoic acid.

Activation of peroxisome proliferator-activated receptor-β/δ (PPAR-β/δ) inhibits human breast cancer cell line tumorigenicity.

Adaptive increase in pyruvate dehydrogenase kinase 4 during starvation is mediated by peroxisome proliferator-activated receptor alpha.

Aryl hydrocarbon receptor antagonism attenuates growth factor expression, proliferation, and migration in fibroblast-like synoviocytes from patients with rheumatoid arthritis

CYP2E1 is not involved in early alcohol-induced liver injury

Chemoprevention of chemically induced skin tumorigenesis by ligand activation of peroxisome proliferator-activated receptor-beta/delta and inhibition of cyclooxygenase 2.

Cholestasis induces reversible accumulation of periplakin in mouse liver.

Comparative in vivo and in vitro analysis of possible estrogenic effects of perfluorooctanoic acid

Di(2-ethylhexyl) phthalate induces a functional zinc deficiency during pregnancy and teratogenesis that is independent of peroxisome proliferator-activated receptor-alpha

Differential hepatic effects of perfluorobutyrate mediated by mouse and human PPAR-alpha.

Dissecting the role of peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) in colon, breast, and lung carcinogenesis.

Editor's Highlight: PPARβ/δ and PPARγ Inhibit Melanoma Tumorigenicity by Modulating Inflammation and Apoptosis.

Editor's Highlight: Perfluorooctane Sulfonate-Choline Ion Pair Formation: A Potential Mechanism Modulating Hepatic Steatosis and Oxidative Stress in Mice

Effect of ligand activation of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) in human lung cancer cell lines

Effect of prenatal peroxisome proliferator-activated receptor alpha (PPARalpha) agonism on postnatal development.

Establishing the Role of PPARβ/δ in Carcinogenesis

Etomoxir-induced PPARalpha-modulated enzymes protect during acute renal failure

Evidence that ligand binding is a key determinant of Ah receptor-mediated transcriptional activity.

Flipping a citrate switch on liver cancer cells

Four-week dietary supplementation with 10- and/or 15-fold basal choline caused decreased body weight in Sprague Dawley rats

Functional characterization of peroxisome proliferator‐activated receptor‐β/δ expression in colon cancer ⬇️

Immunomodulatory action of dietary fish oil and targeted deletion of intestinal epithelial cell PPARδ in inflammation-induced colon carcinogenesis ⬇️

Influence of peroxisome proliferator-activated receptor alpha on ubiquinone biosynthesis

Inhibition of testicular embryonal carcinoma cell tumorigenicity by peroxisome proliferator-activated receptor-β/δ- and retinoic acid receptor-dependent mechanisms

Inhibition of tumorigenesis by peroxisome proliferator-activated receptor (PPAR)-dependent cell cycle blocks in human skin carcinoma cells

Interplay Between the Host, the Human Microbiome, and Drug Metabolism.

Isolation, Characterization, and Purification of Macrophages from Tissues Affected by Obesity-related Inflammation.

Ligand activation of peroxisome proliferator-activated receptor beta inhibits colon carcinogenesis.

Ligand activation of peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta) attenuates carbon tetrachloride hepatotoxicity by downregulating proinflammatory gene expression

Ligand activation of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) and inhibition of cyclooxygenase 2 (COX2) attenuate colon carcinogenesis through independent signaling mechanisms.

Ligand activation of peroxisome proliferator-activated receptor-beta/delta inhibits cell proliferation in human HaCaT keratinocytes.

Ligand activation of peroxisome proliferator-activated receptor-β/δ suppresses liver tumorigenesis in hepatitis B transgenic mice

Lipid metabolism and lipophagy in cancer.

M-CSF from Cancer Cells Induces Fatty Acid Synthase and PPARβ/δ Activation in Tumor Myeloid Cells, Leading to Tumor Progression

Mode of action framework analysis for receptor-mediated toxicity: The peroxisome proliferator-activated receptor alpha (PPARα) as a case study.

Modes of action and species-specific effects of di-(2-ethylhexyl)phthalate in the liver.

Modulation of aryl hydrocarbon receptor (AHR)-dependent signaling by peroxisome proliferator-activated receptor β/δ (PPARβ/δ) in keratinocytes

Modulation of gastrointestinal inflammation and colorectal tumorigenesis by peroxisome proliferator-activated receptor-β/δ (PPARβ/δ)

Molecular Regulation of Carcinogenesis: Friend and Foe

NTP-CERHR expert panel report on the developmental toxicity of soy infant formula.

Nrf2- and PPAR alpha-mediated regulation of hepatic Mrp transporters after exposure to perfluorooctanoic acid and perfluorodecanoic acid.

Omics Approaches To Probe Microbiota and Drug Metabolism Interactions.

PPAR action in insulin resistance unraveled by metabolomics: potential clinical implications

PPAR alpha mediates peroxisome proliferator-induced transcriptional repression of nonperoxisomal gene expression in mouse

PPARalpha and effects of TCE.

PPARbeta/delta protects against experimental colitis through a ligand-independent mechanism.

PPARdelta is pro-tumorigenic in a mouse model of COX-2-induced mammary cancer.

PPARdelta status and mismatch repair mediated neoplasia in the mouse intestine.

PPARgamma influences susceptibility to DMBA-induced mammary, ovarian and skin carcinogenesis.

PPARβ/δ modulates ethanol-induced hepatic effects by decreasing pyridoxal kinase activity.

PPARβ/δ promotes HRAS-induced senescence and tumor suppression by potentiating p-ERK and repressing p-AKT signaling

PPARβ/δ selectively regulates phenotypic features of age-related macular degeneration.

Perfluorooctane Sulfonate-Induced Hepatic Steatosis in Male Sprague Dawley Rats Is Not Attenuated by Dietary Choline Supplementation.

Peroxisome Proliferator-activated Receptor-D (PPARD) Coordinates Mouse Spermatogenesis by Modulating Extracellular Signal-regulated Kinase (ERK)-dependent Signaling.

Peroxisome proliferator-activated receptor alpha mediates the adaptive response to fasting

Peroxisome proliferator-activated receptor beta (delta)-dependent regulation of ubiquitin C expression contributes to attenuation of skin carcinogenesis.

Peroxisome proliferator-activated receptor beta/delta regulates very low density lipoprotein production and catabolism in mice on a Western diet.

Peroxisome proliferator-activated receptor β/δ cross talks with E2F and attenuates mitosis in HRAS-expressing cells.

Peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) ligands inhibit growth of UACC903 and MCF7 human cancer cell lines.

Peroxisome proliferator-activated receptor-delta agonist enhances vasculogenesis by regulating endothelial progenitor cells through genomic and nongenomic activations of the phosphatidylinositol 3-kinase/Akt pathway.

Peroxisome proliferator-activated receptor-delta attenuates colon carcinogenesis.

Peroxisome proliferator-activated receptor-β/δ inhibits human neuroblastoma cell tumorigenesis by inducing p53- and SOX2-mediated cell differentiation.

Peroxisome proliferator-activated receptor-β/δ modulates mast cell phenotype.

Pretreatment with troglitazone decreases lethality during endotoxemia in mice.

Quantitative expression patterns of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) protein in mice

Receptor and nonreceptor-mediated organ-specific toxicity of di(2-ethylhexyl)phthalate (DEHP) in peroxisome proliferator-activated receptor alpha-null mice

Reduced adiposity and liver steatosis by stearoyl-CoA desaturase deficiency are independent of peroxisome proliferator-activated receptor-alpha.

Regulation of Cytochrome P450 2B10 (CYP2B10) Expression in Liver by Peroxisome Proliferator-activated Receptor-β/δ Modulation of SP1 Promoter Occupancy.

Regulation of peroxisome proliferator-activated receptor-alpha by MDM2.

Regulation of peroxisome proliferator-activated receptor-beta/delta by the APC/beta-CATENIN pathway and nonsteroidal antiinflammatory drugs.

Regulatory mechanisms mediated by peroxisome proliferator-activated receptor-β/δ in skin cancer

Sorting out the functional role(s) of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) in cell proliferation and cancer.

Stable over-expression of PPARβ/δ and PPARγ to examine receptor signaling in human HaCaT keratinocytes

Synthesis of isosteric selenium analog of the PPARbeta/delta agonist GW501516 and comparison of biological activity.

Targeting Peroxisome Proliferator-Activated Receptor-β/δ (PPARβ/δ) for Cancer Chemoprevention.

Targeting estrogen receptor-β for the prevention of nonmelanoma skin cancer

The Evolution of Carcinogenesis

The PPARalpha-leukotriene B4 pathway to inflammation control.