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A QA program for MRD testing demonstrates that systematic education can reduce discordance among experienced interpreters

artículo científico publicado en 2017

A Randomized Trial of Three Novel Regimens for Recurrent Acute Myeloid Leukemia Demonstrates the Continuing Challenge of Treating this Difficult Disease

scientific article published on 15 November 2018

A clinical measure of DNA methylation predicts outcome in de novo acute myeloid leukemia

artículo científico publicado en 2016

A genome-wide association study of susceptibility to acute lymphoblastic leukemia in adolescents and young adults

artículo científico publicado en 2014

A marker and putative pathoantigen of Hodgkin's cells

artículo científico publicado en 1989

A new approach to analyzing the utility of immunophenotyping for predicting clinical outcome in acute leukemia. Eastern Cooperative Oncology Group

artículo científico publicado en 1996

A pediatric regimen for older adolescents and young adults with acute lymphoblastic leukemia: results of CALGB 10403

scientific article published on 18 January 2019

A phase 3 study of three induction regimens and of priming with GM-CSF in older adults with acute myeloid leukemia: a trial by the Eastern Cooperative Oncology Group ⬇️

artículo científico publicado el 25 de septiembre de 2003

A phase II clinical trial of interleukin-2 and lymphokine-activated killer cells in advanced colorectal carcinoma

artículo científico publicado en 1994

A phase II trial of arsenic trioxide for relapsed and refractory acute lymphoblastic leukemia.

artículo científico publicado en 2006

A pilot study of alpha-interferon and plicamycin for accelerated phase of chronic myeloid leukemia ⬇️

artículo científico publicado el 1 de mayo de 1997

A pilot study of carboplatin and mitoxantrone in blast crisis of chronic myeloid leukemia

artículo científico publicado en 2009

A randomized placebo-controlled phase III study of granulocyte-macrophage colony-stimulating factor in adult patients (> 55 to 70 years of age) with acute myelogenous leukemia: a study of the Eastern Cooperative Oncology Group (E1490) ⬇️

artículo científico publicado el 15 de julio de 1995

A randomized trial of dasatinib 100 mg versus imatinib 400 mg in newly diagnosed chronic-phase chronic myeloid leukemia

artículo científico publicado en 2012

A randomized trial of induction therapy (daunorubicin, vincristine, prednisone versus daunorubicin, vincristine, prednisone, cytarabine and 6-thioguanine) in adult acute lymphoblastic leukemia with long-term follow-up: an Eastern Cooperative Oncolog ⬇️

artículo científico publicado el 1 de septiembre de 2003

A surrogate marker profile for PML/RAR alpha expressing acute promyelocytic leukemia and the association of immunophenotypic markers with morphologic and molecular subtypes

artículo científico publicado en 2004

Aberrant GSK3β nuclear localization promotes AML growth and drug resistance

artículo científico publicado en 2018

Absence of hereditary p53 mutations in eight familial Hodgkin's disease pedigrees

artículo científico publicado en 1995

Acquired chromosomal anomalies in chronic lymphocytic leukemia patients compared with more than 50,000 quasi-normal participants

artículo científico publicado en 2014

Activating FLT3 mutations in CD117/KIT(+) T-cell acute lymphoblastic leukemias

artículo científico publicado en 2004

Activating mutations in the NT5C2 nucleotidase gene drive chemotherapy resistance in relapsed ALL.

artículo científico publicado en 2013

Acute leukemia with t(10;11)(p11-p15;q13-q23)

artículo científico publicado en 1996

Acute megakaryocytic leukemia: the Eastern Cooperative Oncology Group experience.

artículo científico publicado en 2000

Acute monocytic leukemia (French-American-British classification M5) does not have a worse prognosis than other subtypes of acute myeloid leukemia: a report from the Eastern Cooperative Oncology Group

artículo científico publicado en 2004

Acute myeloid leukaemia expressing the leucocyte integrin CD11b-a new leukaemic syndrome with poor prognosis: result of an ECOG database analysis. Eastern Cooperative Oncology Group

scientific article published on 01 February 1998

Acute myeloid leukemia M4 with inv(16) (p13q22) exhibits a specific immunophenotype with CD2 expression

scientific article published on 01 October 1993

Acute myeloid leukemia with translocation t(8;16) presents with features which mimic acute promyelocytic leukemia and is associated with poor prognosis

scientific article published on 24 October 2012

Adult acute lymphocytic leukemia: the Eastern Cooperative Oncology Group experience

artículo científico publicado el 1 de enero de 1992

Age of onset evidence for anticipation in familial non-Hodgkin's lymphoma

artículo científico publicado en 2000

All-trans retinoic acid and late relapses in acute promyelocytic leukemia: Very long-term follow-up of the North American Intergroup Study I0129 ⬇️

artículo científico publicado el 23 de marzo de 2013

Altered retinoid dose-response of retinoic acid-resistant HL-60 cells.

artículo científico publicado en 1994

Alternatively spliced variants of the human hepatic asialoglycoprotein receptor, H2, differ in cellular trafficking and regulation of phosphorylation ⬇️

artículo científico publicado el 5 de junio de 1992

An activating intragenic deletion in NOTCH1 in human T-ALL ⬇️

artículo científico publicado el 17 de abril de 2012

An integrative genomic and epigenomic approach for the study of transcriptional regulation

artículo científico publicado en 2008

Anthracycline dose intensification in acute myeloid leukemia

artículo científico publicado en 2009

Anticipation in familial chronic lymphocytic leukaemia

artículo científico publicado en 2001

Arsenic trioxide during consolidation for patients with previously untreated low/intermediate risk acute promyelocytic leukaemia may eliminate the need for maintenance therapy

artículo científico publicado en 2014

Arsenic trioxide in front-line therapy of acute promyelocytic leukemia (C9710): prognostic significance of FLT3 mutations and complex karyotype

artículo científico publicado en 2014

At three years, patients with acute lymphoblastic leukaemia are still at risk for relapse. Results of the international MRC UKALLXII/ECOG E2993 trial

artículo científico publicado en 2020

Autologous transplantation gives encouraging results for young adults with favorable-risk acute myeloid leukemia, but is not improved with gemtuzumab ozogamicin ⬇️

artículo científico publicado el 17 de marzo de 2011

Azacitidine with or without Entinostat for the treatment of therapy-related myeloid neoplasm: further results of the E1905 North American Leukemia Intergroup study.

artículo científico publicado en 2015

Base-pair resolution DNA methylation sequencing reveals profoundly divergent epigenetic landscapes in acute myeloid leukemia

artículo científico publicado en 2012

Benefit of high-dose daunorubicin in AML induction extends across cytogenetic and molecular groups

artículo científico publicado en 2016

Biologic heterogeneity in Philadelphia chromosome-positive acute leukemia with myeloid morphology: the Eastern Cooperative Oncology Group experience

artículo científico publicado en 1998

Biotin-dependent expression of the asialoglycoprotein receptor in HepG2

artículo científico publicado en 1988

Biphenotypic leukemia with unusual chromosomal translocation in a patient treated for melanoma

artículo científico publicado en 1986

CD25 expression status improves prognostic risk classification in AML independent of established biomarkers: ECOG phase 3 trial, E1900.

artículo científico publicado en 2012

Cell signaling-based classifier predicts response to induction therapy in elderly patients with acute myeloid leukemia

artículo científico publicado en 2015

Characterization of acute promyelocytic leukemia cases with PML-RAR alpha break/fusion sites in PML exon 6: identification of a subgroup with decreased in vitro responsiveness to all-trans retinoic acid ⬇️

artículo científico publicado el 15 de agosto de 1995

Chemotherapy compared with autologous or allogeneic bone marrow transplantation in the management of acute myeloid leukemia in first remission

artículo científico publicado en 1998

Comments on the 2001 WHO proposal for the classification of haematopoietic neoplasms

artículo científico publicado en 2003

Comparison of the prognostic utility of the revised International Prognostic Scoring System and the French Prognostic Scoring System in azacitidine-treated patients with myelodysplastic syndromes

artículo científico publicado en 2014

Complete resolution of leukemia cutis with sorafenib in an acute myeloid leukemia patient with FLT3-ITD mutation

artículo científico publicado en 2009

Comprehensive assessment of genetic and molecular features predicting outcome in patients with chronic lymphocytic leukemia: results from the US Intergroup Phase III Trial E2997.

artículo científico publicado en 2007

Consensus on MRD in AML?

artículo científico publicado en 2018

Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia

artículo científico publicado en 2014

Conventional adjuvant chemotherapy with or without high-dose chemotherapy and autologous stem-cell transplantation in high-risk breast cancer

artículo científico publicado en 2003

Cytogenetic and phenotypic evolution in a case of acute promyelocytic leukemia

artículo científico publicado en 1986

Cytogenetic prioritization with inclusion of molecular markers predicts outcome in previously untreated patients with chronic lymphocytic leukemia treated with fludarabine or fludarabine plus cyclophosphamide: a long-term follow-up study of the US i

artículo científico publicado en 2015

DNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid leukemia

artículo científico publicado en 2014

DNMT3A Haploinsufficiency Transforms FLT3ITD Myeloproliferative Disease into a Rapid, Spontaneous, and Fully Penetrant Acute Myeloid Leukemia

artículo científico publicado en 2016

DNMT3A mutations promote anthracycline resistance in acute myeloid leukemia via impaired nucleosome remodeling

artículo científico publicado en 2016

Delays in postremission chemotherapy for Philadelphia chromosome negative acute lymphoblastic leukemia are associated with inferior outcomes in patients who undergo allogeneic transplant: An analysis from ECOG 2993/MRC UK ALLXII.

artículo científico publicado en 2016

Delineation of the minimal commonly deleted segment and identification of candidate tumor-suppressor genes in del(9q) acute myeloid leukemia

artículo científico publicado en 2005

Deregulation of DUX4 and ERG in acute lymphoblastic leukemia

artículo científico publicado en 2016

Development of acute megakaryoblastic leukemia in Down syndrome is associated with sequential epigenetic changes

artículo científico publicado en 2013

Differential expression of terminal transferase (TdT) in acute lymphocytic leukaemia expressing myeloid antigens and TdT positive acute myeloid leukaemia as compared to myeloid antigen negative acute lymphocytic leukaemia

artículo científico publicado en 1993

Differential gene expression patterns and interaction networks in BCR-ABL-positive and -negative adult acute lymphoblastic leukemias

artículo científico publicado en 2007

Direct reversal of glucocorticoid resistance by AKT inhibition in acute lymphoblastic leukemia

artículo científico publicado en 2013

Distinct antigen expression related to DNA ploidy in a case of biphenotypic leukemia

artículo científico publicado en 1989

Does microgranular variant morphology of acute promyelocytic leukemia independently predict a less favorable outcome compared with classical M3 APL? A joint study of the North American Intergroup and the PETHEMA Group

artículo científico publicado en 2010

Dynamics of leukemia stem-like cell extinction in acute promyelocytic leukemia

artículo científico publicado en 2014

ETV6 mutations in early immature human T cell leukemias

artículo científico publicado en 2011

Effect of genetic profiling on prediction of therapeutic resistance and survival in adult acute myeloid leukemia

artículo científico publicado en 2015

Efficacy of Retinoids in IKZF1-Mutated BCR-ABL1 Acute Lymphoblastic Leukemia

artículo científico publicado en 2015

Efficacy of fluorescence in situ hybridization for detecting PML/RARA gene fusion in treated and untreated acute promyelocytic leukemia

artículo científico publicado en 1994

Erk Negative Feedback Control Enables Pre-B Cell Transformation and Represents a Therapeutic Target in Acute Lymphoblastic Leukemia

artículo científico publicado en 2015

Erratum: Corrigendum: Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia

artículo científico publicado en 2016

Escalating the intensity of post-remission therapy improves the outcome in acute myeloid leukemia: the ECOG experience. The Eastern Cooperative Oncology Group

artículo científico publicado el 1 de enero de 1992

Etoposide as an in vitro purging agent for the treatment of acute leukemias and lymphomas in conjunction with autologous bone marrow transplantation

scientific article published on 01 August 1986

Evaluation of natural killer and lymphokine-activated killer (LAK) cell activity in vivo in patients treated with high-dose interleukin-2 and adoptive transfer of autologous LAK cells

scientific article published on 01 January 1989

Evidence of a role for functional heterogeneity in multidrug resistance transporters in clinical trials of P-glycoprotein modulation in acute myeloid leukemia

article

Expression of CD25 (interleukin-2 receptor α chain) in adult acute lymphoblastic leukemia predicts for the presence of BCR/ABL fusion transcripts: results of a preliminary laboratory analysis of ECOG/MRC Intergroup Study E2993 ⬇️

artículo científico publicado el 1 de noviembre de 1997

Expression of cell-surface antigens in acute promyelocytic leukaemia

artículo científico publicado en 2003

Expression of retinoic acid receptor-alpha mRNA in human leukemia cells with variable responsiveness to retinoic acid.

artículo científico publicado en 1989

Extramedullary Disease in Adult Acute Myeloid Leukemia Is Common but Lacks Independent Significance: Analysis of Patients in ECOG-ACRIN Cancer Research Group Trials, 1980-2008.

artículo científico publicado en 2016

Extramedullary acute myeloid leukemia presenting in young adults demonstrates sensitivity to high-dose anthracycline: a subset analysis from ECOG-ACRIN 1900

scholarly article by Hugo F Fernandez et al published April 2019 in Haematologica

Failure of three novel regimens to improve outcome for patients with relapsed or refractory acute myeloid leukaemia: a report from the Eastern Cooperative Oncology Group

artículo científico publicado en 2009

Follicular lymphoma patients with KIR2DL2 and KIR3DL1 and their ligands (HLA-C1 and HLA-Bw4) show improved outcome when receiving rituximab

scholarly article by Amy K Erbe et al published 12 March 2019 in Journal for Immunotherapy of Cancer

Functional Pathway Analysis Using SCNP of FLT3 Receptor Pathway Deregulation in AML Provides Prognostic Information Independent from Mutational Status ⬇️

artículo científico publicado el 19 de febrero de 2013

Functional pathway analysis in acute myeloid leukemia using single cell network profiling assay: Effect of specimen source (bone marrow or peripheral blood) on assay readouts ⬇️

artículo científico publicado el 14 de febrero de 2012

Functional screen of MSI2 interactors identifies an essential role for SYNCRIP in myeloid leukemia stem cells

artículo científico publicado en 2017

Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies

artículo científico publicado en 2009

Genetic inactivation of the polycomb repressive complex 2 in T cell acute lymphoblastic leukemia

artículo científico publicado en 2012

Genetic loss of SH2B3 in acute lymphoblastic leukemia

scientific article published on August 2013

Genomic analyses identify recurrent MEF2D fusions in acute lymphoblastic leukaemia

artículo científico publicado en 2016

HL-T, a new cell line derived from HL-60 promyelocytic leukemia cell cultures expressing terminal transferase and secreting suppressor activity.

artículo científico publicado en 1987

High Frequency and Poor Outcome of Philadelphia Chromosome-Like Acute Lymphoblastic Leukemia in Adults

artículo científico publicado en 2016

Hodgkin's cell lectin, a lymphocyte adhesion molecule and mitogen

How to optimize multiparameter flow cytometry for leukaemia/lymphoma diagnosis ⬇️

artículo científico publicado el 1 de diciembre de 2003

IL1RAP potentiates multiple oncogenic signaling pathways in AML

scientific article published on 17 May 2018

Idarubicin and standard-dose cytosine arabinoside in adults with recurrent and refractory acute lymphocytic leukemia

artículo científico publicado en 2004

Identification of FOXM1 as a therapeutic target in B-cell lineage acute lymphoblastic leukaemia

artículo científico publicado en 2015

Imatinib 800 mg daily induces deeper molecular responses than imatinib 400 mg daily: results of SWOG S0325, an intergroup randomized PHASE II trial in newly diagnosed chronic phase chronic myeloid leukaemia

artículo científico publicado en 2013

Immunophenotypic features of t(8;21) (q22;q22) acute myeloid leukemia in adults

scientific article published on 01 April 1993

Immunophenotyping in hematologic malignancies: state of the art. Preface

artículo científico publicado en 2010

In Ph+BCR-ABL1P210+ acute lymphoblastic leukemia the e13a2 (B2A2) transcript is prevalent

artículo científico publicado en 2019

In adults with standard-risk acute lymphoblastic leukemia, the greatest benefit is achieved from a matched sibling allogeneic transplantation in first complete remission, and an autologous transplantation is less effective than conventional consolid

artículo científico publicado en 2007

Incidence of therapy-related myeloid neoplasia after initial therapy for chronic lymphocytic leukemia with fludarabine-cyclophosphamide versus fludarabine: long-term follow-up of US Intergroup Study E2997.

artículo científico publicado en 2011

Independent Prognostic Significance of Monosomy 17 and Impact of Karyotype Complexity in Monosomal Karyotype/Complex Karyotype Acute Myeloid Leukemia: Results from Four ECOG-ACRIN Prospective Therapeutic Trials

artículo científico publicado en 2017

Inhibition of the mutated c-KIT kinase in AML1-ETO-positive leukemia cells restores sensitivity to PARP inhibitor

scientific article published on 01 December 2019

Integrated genomic DNA/RNA profiling of hematologic malignancies in the clinical setting

artículo científico

Integrative epigenomic analysis identifies biomarkers and therapeutic targets in adult B-acute lymphoblastic leukemia

artículo científico publicado en 2012

Integrative genomic analyses reveal mechanisms of glucocorticoid resistance in acute lymphoblastic leukemia

scientific article published on 09 March 2020

Intensified induction chemotherapy in adult acute myeloid leukemia followed by high-dose chemotherapy and autologous peripheral blood stem cell transplantation: an Eastern Cooperative Oncology Group trial (E4995).

artículo científico publicado en 2005

Inv(16) occurring in a case of acute biphenotypic leukemia lacking monocytic markers: multiple but short remissions

artículo científico publicado en 1987

Karyotype is an independent prognostic factor in adult acute lymphoblastic leukemia (ALL): analysis of cytogenetic data from patients treated on the Medical Research Council (MRC) UKALLXII/Eastern Cooperative Oncology Group (ECOG) 2993 trial

artículo científico publicado en 2006

Karyotypic analysis predicts outcome of preremission and postremission therapy in adult acute myeloid leukemia: a Southwest Oncology Group/Eastern Cooperative Oncology Group Study

artículo científico publicado en 2000

Lenalidomide and prednisone for myelofibrosis: Eastern Cooperative Oncology Group (ECOG) phase 2 trial E4903.

artículo científico publicado en 2010

Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation

artículo científico publicado en 2010

Leukemic cellular retinoic acid resistance and missense mutations in the PML-RARalpha fusion gene after relapse of acute promyelocytic leukemia from treatment with all-trans retinoic acid and intensive chemotherapy.

artículo científico publicado en 1998

Levels of soluble interleukin-2 receptors are predictive of response in patients treated with interleukin-2 and lymphokine-activated killer cells

artículo científico publicado en 1995

Long-term survival in acute myeloid leukemia: the Eastern Cooperative Oncology Group experience

artículo científico publicado en 1997

Low expression of the myeloid differentiation antigen CD65s, a feature of poorly differentiated AML in older adults: study of 711 patients enrolled in ECOG trials

artículo científico publicado en 2003

Lymphoid lineage-associated features in acute myeloid leukaemia: phenotypic and genotypic correlations

artículo científico publicado en 1992

MDS and secondary AML display unique patterns and abundance of aberrant DNA methylation

scientific article published on 03 August 2009

MEF2C phosphorylation is required for chemotherapy resistance in acute myeloid leukemia.

artículo científico publicado en 2018

MLL tandem duplication and multiple splicing in adult acute myeloid leukemia with normal karyotype

artículo científico publicado en 1996

Mantle cell lymphoma initial therapy with abbreviated R-CHOP followed by 90Y-ibritumomab tiuxetan: 10-year follow-up of the phase 2 ECOG-ACRIN study E1499.

artículo científico publicado en 2016

Mechanistic rationale for targeting the unfolded protein response in pre-B acute lymphoblastic leukemia

artículo científico publicado en 2014

Minimal Residual Disease in AML: Why Has It Lagged Behind Pediatric ALL?

artículo científico publicado en 2015

Minimal residual disease in acute myeloid leukemia: coming of age

artículo científico publicado el 1 de enero de 2012

Mitoxantrone, etoposide, and cytarabine plus cyclosporine for patients with relapsed or refractory acute myeloid leukemia: an Eastern Cooperative Oncology Group pilot study.

artículo científico publicado en 1999

Mitoxantrone, etoposide, and cytarabine with or without valspodar in patients with relapsed or refractory acute myeloid leukemia and high-risk myelodysplastic syndrome: a phase III trial (E2995)

artículo científico publicado en 2004

Modified VAD and PSC-833 in the treatment of resistant or relapsing chronic lymphocytic leukemia (E4996): a trial of the Eastern Cooperative Oncology Group

artículo científico publicado en 2004

Modulation of multidrug resistance in de novo adult acute myeloid leukemia: variable efficacy of reverting agents in vitro. Eastern Cooperative Oncology Group

scientific article published on 01 March 1995

Monosomy 7 in multilineage and acute lymphoblastic leukaemia

artículo científico publicado en 1991

Morphologic classification of acute myeloid leukemia: concordance among Eastern Cooperative Oncology Group investigators: a comment

artículo científico publicado en 1996

Musashi2 sustains the mixed-lineage leukemia-driven stem cell regulatory program

artículo científico publicado en 2015

Mutated Ptpn11 alters leukemic stem cell frequency and reduces the sensitivity of acute myeloid leukemia cells to Mcl1 inhibition

artículo científico publicado en 2015

Mutational analysis of candidate tumor-associated genes in acute megakaryoblastic leukemia

artículo científico publicado en 2009

Mutational cooperativity linked to combinatorial epigenetic gain of function in acute myeloid leukemia

artículo científico publicado en 2015

Myeloid/natural killer cell acute leukemia: a previously unrecognized form of acute leukemia potentially misdiagnosed as FAB-M3 acute myeloid leukemia ⬇️

artículo científico publicado el 15 de octubre de 1994

New IDH1 mutant inhibitors for treatment of acute myeloid leukemia

artículo científico publicado en 2015

Objective Response of Multiple Myeloma to Cyclosporin A ⬇️

artículo científico publicado el 1 de diciembre de 1994

Oncogenic hijacking of the stress response machinery in T cell acute lymphoblastic leukemia

scientific article published on 23 July 2018

Overexpression of IL-1 receptor accessory protein in stem and progenitor cells and outcome correlation in AML and MDS.

artículo científico publicado en 2012

PAX5-driven subtypes of B-progenitor acute lymphoblastic leukemia

scientific article published on 14 January 2019

PHF6 mutations in T-cell acute lymphoblastic leukemia

artículo científico publicado en 2010

PHF6 mutations in adult acute myeloid leukemia

artículo científico publicado en 2010

PRMT4 blocks myeloid differentiation by assembling a methyl-RUNX1-dependent repressor complex

artículo científico publicado en 2013

Pentostatin, Cyclophosphamide, and Rituximab Followed by Alemtuzumab for Relapsed or Refractory Chronic Lymphocytic Leukemia: A Phase 2 Trial of the ECOG-Acrin Cancer Research Group (E2903)

scientific article published on 23 July 2019

Phase 2 study of VcR-CVAD with maintenance rituximab for untreated mantle cell lymphoma: an Eastern Cooperative Oncology Group study (E1405).

scientific article published on 23 January 2014

Phase I clinical and pharmacokinetic study of taxol

artículo científico publicado en 1987

Phase II study of all-trans retinoic acid in the accelerated phase or early blastic phase of chronic myeloid leukemia: a study of the Eastern Cooperative Oncology Group (E1993).

artículo científico publicado en 2005

Phase II study of carboplatin in blast crisis of chronic myeloid leukemia: Eastern Cooperative Oncology Group Study E1992 ⬇️

artículo científico publicado el 1 de julio de 1998

Phase II study of combination human recombinant GM-CSF with intermediate-dose cytarabine and mitoxantrone chemotherapy in patients with high-risk myelodysplastic syndromes (RAEB, RAEBT, and CMML): an Eastern Cooperative Oncology Group Study

artículo científico publicado en 2001

Phase II study of mitoxantrone and 5-azacytidine for accelerated and blast crisis of chronic myelogenous leukemia: a study of the Eastern Cooperative Oncology Group

artículo científico publicado el 1 de agosto de 1992

Phase II study of rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone immunochemotherapy followed by yttrium-90-ibritumomab tiuxetan in untreated mantle-cell lymphoma: Eastern Cooperative Oncology Group Study E1499

artículo científico publicado en 2012

Phase II study of theophylline in chronic lymphocytic leukemia: a study of the Eastern Cooperative Oncology Group (E4998).

artículo científico publicado en 2004

Phase II trial of 2-chlorodeoxyadenosine in patients with relapsed/refractory acute myeloid leukemia: a study of the Eastern Cooperative Oncology Group (ECOG), E5995

scientific article published on 01 October 2000

Phase II trial of subcutaneous recombinant human interleukin 11 with subcutaneous recombinant human granulocyte-macrophage colony stimulating factor in patients with acute myeloid leukemia (AML) receiving high-dose cytarabine during induction: ECOG

artículo científico publicado en 2006

Phase III trial of fludarabine plus cyclophosphamide compared with fludarabine for patients with previously untreated chronic lymphocytic leukemia: US Intergroup Trial E2997.

artículo científico publicado en 2007

Phf6 Loss Enhances HSC Self-Renewal Driving Tumor Initiation and Leukemia Stem Cell Activity in T-ALL

scientific article published on 19 December 2018

Philadelphia chromosome positive essential thrombocythemia evolving into lymphoid blast crisis

artículo científico publicado en 1987

Plasma cell leukemia with an unusual karyotype and prolonged survival following oral alkylating agent therapy

artículo científico publicado en 1987

Plasma cell leukemia with an unusual karyotype and prolonged survival with oral alkylating agent therapy

artículo científico publicado en 1987

Plasmacytoid blast crisis in B-cell chronic lymphocytic leukemia: effect of estradiol on growth and differentiation in vitro

artículo científico publicado en 1985

Platelet count doubling after the first cycle of azacitidine therapy predicts eventual response and survival in patients with myelodysplastic syndromes and oligoblastic acute myeloid leukaemia but does not add to prognostic utility of the revised IP

artículo científico publicado en 2014

Preclinical analysis of the γ-secretase inhibitor PF-03084014 in combination with glucocorticoids in T-cell acute lymphoblastic leukemia

artículo científico publicado en 2012

Prognostic implications of NOTCH1 and FBXW7 mutations in adults with T-cell acute lymphoblastic leukemia treated on the MRC UKALLXII/ECOG E2993 protocol

artículo científico publicado en 2009

Prognostic implications of additional chromosome abnormalities among patients with de novo acute promyelocytic leukemia with t(15;17) ⬇️

artículo científico publicado el 22 de mayo de 2012

Prognostic importance of TLX1 (HOX11) oncogene expression in adults with T-cell acute lymphoblastic leukaemia

artículo científico publicado en 2004

Prognostic relevance of integrated genetic profiling in acute myeloid leukemia

artículo científico publicado en 2012

Prognostic relevance of integrated genetic profiling in adult T-cell acute lymphoblastic leukemia

artículo científico publicado en 2013

Prolonged administration of azacitidine with or without entinostat for myelodysplastic syndrome and acute myeloid leukemia with myelodysplasia-related changes: results of the US Leukemia Intergroup trial E1905.

artículo científico publicado en 2014

Prospective outcome data on 267 unselected adult patients with Philadelphia chromosome-positive acute lymphoblastic leukemia confirms superiority of allogeneic transplantation over chemotherapy in the pre-imatinib era: results from the International

artículo científico publicado en 2009

RAR alpha1/RAR alpha2-PML mRNA expression in acute promyelocytic leukemia cells: a molecular and laboratory-clinical correlative study

scientific article published on 01 July 1997

Rare adult acute lymphocytic leukemia with CD56 expression in the ECOG experience shows unexpected phenotypic and genotypic heterogeneity

artículo científico publicado en 2001

Rational Targeting of Cooperating Layers of the Epigenome Yields Enhanced Therapeutic Efficacy against AML

scientific article published on 10 May 2019

Reappearance of acute myeloid leukemia after almost 23 years of continuous complete remission.

artículo científico publicado en 2009

Reverse engineering of TLX oncogenic transcriptional networks identifies RUNX1 as tumor suppressor in T-ALL.

artículo científico publicado en 2012

SOX4 enables oncogenic survival signals in acute lymphoblastic leukemia ⬇️

artículo científico publicado el 14 de noviembre de 2012

Self-enforcing feedback activation between BCL6 and pre-B cell receptor signaling defines a distinct subtype of acute lymphoblastic leukemia

artículo científico publicado en 2015

Serum 2-hydroxyglutarate levels predict isocitrate dehydrogenase mutations and clinical outcome in acute myeloid leukemia ⬇️

artículo científico publicado el 2 de mayo de 2013

Should minimal residual disease guide therapy in AML?

artículo científico

Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia

artículo científico publicado en 2015

Significantly lower P-glycoprotein expression in acute promyelocytic leukemia than in other types of acute myeloid leukemia: immunological, molecular and functional analyses.

artículo científico publicado en 1994

Stability of multiple antigen receptor gene rearrangements and immunophenotype in Hodgkin's disease-derived cell line L428 and variant subline L428KSA

scientific article published on 01 July 1989

Surrogate marker profiles for genetic lesions in acute leukemias ⬇️

artículo científico publicado el 29 de octubre de 2010

Survival after phase II treatment of advanced renal cell carcinoma with taxol or high-dose interleukin-2

artículo científico publicado en 1993

Survival more than 19 years after the diagnosis of accelerated phase of chronic myelocytic leukemia

artículo científico publicado el 1 de marzo de 2011

Synergistic antileukemic therapies in NOTCH1-induced T-ALL.

artículo científico publicado en 2017

T-cell acute lymphoblastic leukemia in adults: clinical features, immunophenotype, cytogenetics, and outcome from the large randomized prospective trial (UKALL XII/ECOG 2993)

artículo científico publicado en 2009

TGFβR-SMAD3 Signaling Induces Resistance to PARP Inhibitors in the Bone Marrow Microenvironment

artículo científico publicado en 2020

Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia

artículo científico publicado en 2014

Targeted detection and quantitation of histone modifications from 1,000 cells

scientific article published on 26 October 2020

TdT+/nonlymphoid antigen+ acute leukemias: immunologic and karyotypic monitoring during therapy and at relapse suggests the transformation of a bipotential stem cell.

artículo científico publicado en 1989

Telomere Length Recovery: A Strong Predictor of Overall Survival in Acute Promyelocytic Leukemia

artículo científico publicado en 2016

Terminal transferase expression in acute myeloid leukaemia: biology and prognosis

scientific article published on 01 May 1991

Terminal transferase positive acute promyelocytic leukemia: in vitro differentiation of a T-lymphocytic/promyelocytic hybrid phenotype

scientific article published on 01 January 1985

The 5q-- deletion: correlation of breakpoints with the immunophenotype of leukemic blast cells

artículo científico publicado en 1987

The TLX1 oncogene drives aneuploidy in T cell transformation

artículo científico publicado en 2010

The clinical characteristics, therapy and outcome of 85 adults with acute lymphoblastic leukemia and t(4;11)(q21;q23)/MLL-AFF1 prospectively treated in the UKALLXII/ECOG2993 trial

artículo científico publicado en 2013

The evolving role of chemotherapy and hematopoietic cell transplants in Ph-positive acute lymphoblastic leukemia in adults

artículo científico publicado en 2017

The immunophenotype of acute promyelocytic leukemia (APL): an ECOG study

artículo científico publicado en 1994

Three-dimensional chromatin landscapes in T cell acute lymphoblastic leukemia

artículo científico publicado en 2020

Transformation of myeloma into Ph1-negative CML with plasma cell antigens

scientific article published on 01 July 1985

Translocation t(12;19)(q13;q13.3). A new recurrent abnormality in acute nonlymphocytic leukemia with atypical erythropoiesis

artículo científico publicado en 1988

Treatment of myelodysplastic syndrome patients with erythropoietin with or without granulocyte colony-stimulating factor: results of a prospective randomized phase 3 trial by the Eastern Cooperative Oncology Group (E1996).

artículo científico publicado en 2009

Treatment of poor prognosis AML patients using PSC833 (valspodar) plus mitoxantrone, etoposide, and cytarabine (PSC-MEC).

artículo científico publicado en 1999

Treatment of refractory and relapsed acute myelogenous leukemia with combination chemotherapy plus the multidrug resistance modulator PSC 833 (Valspodar).

artículo científico publicado en 1999

Treatment-influenced associations of PML-RARα mutations, FLT3 mutations, and additional chromosome abnormalities in relapsed acute promyelocytic leukemia

artículo científico publicado en 2012

Truncating Erythropoietin Receptor Rearrangements in Acute Lymphoblastic Leukemia

artículo científico publicado en 2016

Tumor-specific HSP90 inhibition as a therapeutic approach in JAK-mutant acute lymphoblastic leukemias

artículo científico publicado en 2015

UKALLXII/ECOG2993: addition of imatinib to a standard treatment regimen enhances long-term outcomes in Philadelphia positive acute lymphoblastic leukemia

artículo científico publicado en 2013

US Intergroup Study of Chemotherapy Plus Dasatinib and Allogeneic Stem Cell Transplant in Philadelphia Chromosome Positive ALL

artículo científico publicado en 2016

Unexpected immunoglobulin light chain gene rearrangements in myeloid antigen positive acute lymphoid leukemia ⬇️

artículo científico publicado el 1 de enero de 1991

Very late relapse of AML after allogeneic hematopoietic cell transplantation is often extramedullary

artículo científico publicado en 2016

Very poor long-term survival in past and more recent studies for relapsed AML patients: The ECOG-ACRIN experience

artículo científico publicado en 2018

WT1 mutations in T-ALL

artículo científico publicado en 2009

When it comes to MRD, AML ≠ ALL ⬇️

artículo científico publicado el 23 de agosto de 2012

Younger adults with acute myeloid leukemia in remission for ≥ 3 years have a high likelihood of cure: The ECOG experience in over 1200 patients

artículo científico publicado en 2014

Zosuquidar, a novel modulator of P-glycoprotein, does not improve the outcome of older patients with newly diagnosed acute myeloid leukemia: a randomized, placebo-controlled trial of the Eastern Cooperative Oncology Group 3999

artículo científico publicado en 2010

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