Lista de obras - J.W.M. Heemskerk - Dominio Público Uruguay

A dominant gain-of-function mutation in universal tyrosine kinase SRC causes thrombocytopenia, myelofibrosis, bleeding, and bone pathologies

artículo científico publicado en 2016

Atherosclerotic geometries exacerbate pathological thrombus formation poststenosis in a von Willebrand factor-dependent manner

artículo científico publicado en 2013

Biogenesis of G-protein mediated calcium signaling in human megakaryocytes

artículo científico publicado el 1 de octubre de 2001

Collagen but not fibrinogen surfaces induce bleb formation, exposure of phosphatidylserine, and procoagulant activity of adherent platelets: evidence for regulation by protein tyrosine kinase-dependent Ca2+ responses ⬇️

artículo científico publicado el 1 de octubre de 1997

Complementary roles of platelets and coagulation in thrombus formation on plaques acutely ruptured by targeted ultrasound treatment: a novel intravital model

artículo científico publicado en 2008

Cyclic AMP Raises Intracellular Ca 2+ in Human Megakaryocytes Independent of Protein Kinase A ⬇️

artículo científico publicado el 1 de enero de 2002

Decreased responsiveness and development of activation markers of PLTs stored in plasma

artículo científico publicado en 2004

Dividing VI by X(a) ⬇️

artículo científico publicado el 7 de abril de 2011

Do dietary fatty acids affect platelet aggregation and arterial thrombosis tendency in a rat model?

artículo científico publicado el 1 de octubre de 1992

Dual Mechanism of Integrin αIIbβ3 Closure in Procoagulant Platelets ⬇️

artículo científico publicado el 21 de marzo de 2013

Dual-specificity phosphatase 3 deficiency or inhibition limits platelet activation and arterial thrombosis ⬇️

artículo científico publicado en 2014

Effect of membrane-permeable sulfhydryl reagents and depletion of glutathione on calcium mobilisation in human platelets ⬇️

artículo científico publicado el 15 de mayo de 1997

Galectin-1 and platelet factor 4 (CXCL4) induce complementary platelet responses in vitro

artículo científico publicado en 2021

Genetic analysis of the role of protein kinase Ctheta in platelet function and thrombus formation

artículo científico publicado en 2008

Glycoprotein VI but not alpha2beta1 integrin is essential for platelet interaction with collagen

artículo científico publicado en 2001

Hypocoagulant and Lipid-Lowering Effects of Dietary n-3 Polyunsaturated Fatty Acids With Unchanged Platelet Activation in Rats ⬇️

artículo científico publicado el 1 de septiembre de 1998

Identification of platelet function defects by multi-parameter assessment of thrombus formation

artículo científico publicado en 2014

Intravital imaging of thrombus formation in small and large mouse arteries: experimentally induced vascular damage and plaque rupture in vivo

artículo científico publicado en 2012

Key role of glycoprotein Ib/V/IX and von Willebrand factor in platelet activation-dependent fibrin formation at low shear flow

artículo científico publicado en 2011

Kinetics of store-operated Ca2+ influx evoked by endomembrane Ca2+-ATPase inhibitors in human platelets ⬇️

artículo científico publicado el 1 de octubre de 1997

Microparticles from apoptotic platelets promote resident macrophage differentiation.

artículo científico publicado en 2011

Modulation of rat platelet activation by vessel wall-derived prostaglandin and platelet-derived thromboxane: effects of dietary fish oil on thromboxane-prostaglandin balance

artículo científico publicado en 2001

Molecular MRI of early thrombus formation using a bimodal alpha2-antiplasmin-based contrast agent

artículo científico publicado en 2009

Molecular functions of anoctamin 6 (TMEM16F): a chloride channel, cation channel, or phospholipid scramblase? ⬇️

artículo científico publicado el 8 de junio de 2013

New Fundamentals in Hemostasis ⬇️

artículo científico publicado el 1 de enero de 2013

Nonredundant Roles of Platelet Glycoprotein VI and Integrin αIIbβ3 in Fibrin-Mediated Microthrombus Formation

scientific article published on 03 December 2020

Novel methodology for assessment of prophylactic platelet transfusion therapy by measuring increased thrombus formation and thrombin generation

artículo científico publicado en 2006

OC-08 - Multiple functional defects in platelets from thrombocytopenic cancer patients undergoing chemotherapy

artículo científico publicado en 2016

Overexpression of the platelet P2X1 ion channel in transgenic mice generates a novel prothrombotic phenotype

artículo científico publicado en 2003

PKCalpha regulates platelet granule secretion and thrombus formation in mice

artículo científico publicado en 2009

Plasminogen associates with phosphatidylserine-exposing platelets and contributes to thrombus lysis under flow

artículo científico publicado en 2015

Platelet CD40L mediates thrombotic and inflammatory processes in atherosclerosis

artículo científico publicado en 2010

Platelet calcium signaling by G-protein coupled and ITAM-linked receptors regulating anoctamin-6 and procoagulant activity

artículo científico publicado en 2020

Platelet dysfunction in thrombosis patients treated with vitamin K antagonists and recurrent bleeding

artículo científico publicado en 2013

Platelet function is modified by common sequence variation in megakaryocyte super enhancers

artículo científico publicado en 2017

Platelet-based coagulation: different populations, different functions

artículo científico publicado en 2013

Polyphosphates: a link between platelet activation, intrinsic coagulation and inflammation? ⬇️

artículo científico publicado el 1 de junio de 2010

Ragged spiking of free calcium in ADP-stimulated human platelets: regulation of puff-like calcium signals in vitro and ex vivo

artículo científico publicado en 2001

Receptors and signalling mechanisms in the procoagulant response of platelets

artículo científico publicado en 2000

Recombinant factor VIIa enhances platelet adhesion and activation under flow conditions at normal and reduced platelet count

artículo científico publicado en 2005

Role of newly formed platelets in thrombus formation in rat after clopidogrel treatment: comparison to the reversible binding P2Y12 antagonist ticagrelor ⬇️

artículo científico publicado el 10 de noviembre de 2011

Roles of platelet STIM1 and Orai1 in glycoprotein VI- and thrombin-dependent procoagulant activity and thrombus formation

artículo científico publicado en 2010

Segregation of platelet aggregatory and procoagulant microdomains in thrombus formation: regulation by transient integrin activation

artículo científico publicado en 2007

Shedding of procoagulant microparticles from unstimulated platelets by integrin-mediated destabilization of actin cytoskeleton.

artículo científico publicado en 2006

Spatial distribution of factor Xa, thrombin, and fibrin(ogen) on thrombi at venous shear

artículo científico publicado en 2010

Spiking in cytosolic calcium concentration in single fibrinogen-bound fura-2-loaded human platelets ⬇️

artículo científico publicado el 15 de abril de 1992

Stabilizing role of platelet P2Y(12) receptors in shear-dependent thrombus formation on ruptured plaques

artículo científico publicado en 2010

The Amino Acid Homoarginine Inhibits Atherogenesis by Modulating T-Cell Function

artículo científico publicado en 2022

Transcriptional diversity during lineage commitment of human blood progenitors

artículo científico publicado en 2014

αIIbβ3 variants defined by next-generation sequencing: predicting variants likely to cause Glanzmann thrombasthenia

artículo científico publicado en 2015

Lista de obras de J.W.M. Heemskerk

A dominant gain-of-function mutation in universal tyrosine kinase SRC causes thrombocytopenia, myelofibrosis, bleeding, and bone pathologies

Atherosclerotic geometries exacerbate pathological thrombus formation poststenosis in a von Willebrand factor-dependent manner

Biogenesis of G-protein mediated calcium signaling in human megakaryocytes

Collagen but not fibrinogen surfaces induce bleb formation, exposure of phosphatidylserine, and procoagulant activity of adherent platelets: evidence for regulation by protein tyrosine kinase-dependent Ca2+ responses ⬇️

Complementary roles of platelets and coagulation in thrombus formation on plaques acutely ruptured by targeted ultrasound treatment: a novel intravital model

Cyclic AMP Raises Intracellular Ca 2+ in Human Megakaryocytes Independent of Protein Kinase A ⬇️

Decreased responsiveness and development of activation markers of PLTs stored in plasma

Dividing VI by X(a) ⬇️

Do dietary fatty acids affect platelet aggregation and arterial thrombosis tendency in a rat model?

Dual Mechanism of Integrin αIIbβ3 Closure in Procoagulant Platelets ⬇️

Dual-specificity phosphatase 3 deficiency or inhibition limits platelet activation and arterial thrombosis ⬇️

Effect of membrane-permeable sulfhydryl reagents and depletion of glutathione on calcium mobilisation in human platelets ⬇️

Galectin-1 and platelet factor 4 (CXCL4) induce complementary platelet responses in vitro

Genetic analysis of the role of protein kinase Ctheta in platelet function and thrombus formation

Glycoprotein VI but not alpha2beta1 integrin is essential for platelet interaction with collagen

Hypocoagulant and Lipid-Lowering Effects of Dietary n-3 Polyunsaturated Fatty Acids With Unchanged Platelet Activation in Rats ⬇️

Identification of platelet function defects by multi-parameter assessment of thrombus formation

Intravital imaging of thrombus formation in small and large mouse arteries: experimentally induced vascular damage and plaque rupture in vivo

Key role of glycoprotein Ib/V/IX and von Willebrand factor in platelet activation-dependent fibrin formation at low shear flow

Kinetics of store-operated Ca2+ influx evoked by endomembrane Ca2+-ATPase inhibitors in human platelets ⬇️

Microparticles from apoptotic platelets promote resident macrophage differentiation.

Modulation of rat platelet activation by vessel wall-derived prostaglandin and platelet-derived thromboxane: effects of dietary fish oil on thromboxane-prostaglandin balance

Molecular MRI of early thrombus formation using a bimodal alpha2-antiplasmin-based contrast agent

Molecular functions of anoctamin 6 (TMEM16F): a chloride channel, cation channel, or phospholipid scramblase? ⬇️

New Fundamentals in Hemostasis ⬇️

Nonredundant Roles of Platelet Glycoprotein VI and Integrin αIIbβ3 in Fibrin-Mediated Microthrombus Formation

Novel methodology for assessment of prophylactic platelet transfusion therapy by measuring increased thrombus formation and thrombin generation

OC-08 - Multiple functional defects in platelets from thrombocytopenic cancer patients undergoing chemotherapy

Overexpression of the platelet P2X1 ion channel in transgenic mice generates a novel prothrombotic phenotype

PKCalpha regulates platelet granule secretion and thrombus formation in mice

Plasminogen associates with phosphatidylserine-exposing platelets and contributes to thrombus lysis under flow

Platelet CD40L mediates thrombotic and inflammatory processes in atherosclerosis

Platelet calcium signaling by G-protein coupled and ITAM-linked receptors regulating anoctamin-6 and procoagulant activity

Platelet dysfunction in thrombosis patients treated with vitamin K antagonists and recurrent bleeding

Platelet function is modified by common sequence variation in megakaryocyte super enhancers

Platelet-based coagulation: different populations, different functions

Polyphosphates: a link between platelet activation, intrinsic coagulation and inflammation? ⬇️

Ragged spiking of free calcium in ADP-stimulated human platelets: regulation of puff-like calcium signals in vitro and ex vivo

Receptors and signalling mechanisms in the procoagulant response of platelets

Recombinant factor VIIa enhances platelet adhesion and activation under flow conditions at normal and reduced platelet count

Role of newly formed platelets in thrombus formation in rat after clopidogrel treatment: comparison to the reversible binding P2Y12 antagonist ticagrelor ⬇️

Roles of platelet STIM1 and Orai1 in glycoprotein VI- and thrombin-dependent procoagulant activity and thrombus formation

Segregation of platelet aggregatory and procoagulant microdomains in thrombus formation: regulation by transient integrin activation

Shedding of procoagulant microparticles from unstimulated platelets by integrin-mediated destabilization of actin cytoskeleton.

Spatial distribution of factor Xa, thrombin, and fibrin(ogen) on thrombi at venous shear

Spiking in cytosolic calcium concentration in single fibrinogen-bound fura-2-loaded human platelets ⬇️

Stabilizing role of platelet P2Y(12) receptors in shear-dependent thrombus formation on ruptured plaques

The Amino Acid Homoarginine Inhibits Atherogenesis by Modulating T-Cell Function

Transcriptional diversity during lineage commitment of human blood progenitors

αIIbβ3 variants defined by next-generation sequencing: predicting variants likely to cause Glanzmann thrombasthenia