Lista de obras - J C Portais - Dominio Público Uruguay

A methodology for the validation of isotopic analyses by mass spectrometry in stable-isotope labelling experiments

artículo científico publicado en 2017

A novel platform for automated high-throughput fluxome profiling of metabolic variants.

artículo científico publicado en 2014

Ablation of succinate production from glucose metabolism in the procyclic trypanosomes induces metabolic switches to the glycerol 3-phosphate/dihydroxyacetone phosphate shuttle and to proline metabolism.

artículo científico publicado en 2010

Acetate Exposure Determines the Diauxic Behavior of Escherichia coli during the Glucose-Acetate Transition.

artículo científico publicado en 2015

Acetate fluxes in Escherichia coli are determined by the thermodynamic control of the Pta-AckA pathway.

scientific article published on 10 February 2017

An optimization method for untargeted MS-based isotopic tracing investigations of metabolism

artículo científico publicado en 2022

Application of 2D-TOCSY NMR to the measurement of specific(13C-enrichments in complex mixtures of 13C-labeled metabolites.

artículo científico publicado en 2007

Bio-based succinate from sucrose: High-resolution 13C metabolic flux analysis and metabolic engineering of the rumen bacterium Basfia succiniciproducens.

artículo científico publicado en 2017

Biofilm microenvironment induces a widespread adaptive amino-acid fermentation pathway conferring strong fitness advantage in Escherichia coli.

artículo científico publicado en 2017

Carbohydrate cycling in micro-organisms: what can (13)C-NMR tell us?

artículo científico publicado en 2002

Chemotherapy-Resistant Human Acute Myeloid Leukemia Cells Are Not Enriched for Leukemic Stem Cells but Require Oxidative Metabolism

artículo científico publicado en 2017

Chromatin-Bound MDM2 Regulates Serine Metabolism and Redox Homeostasis Independently of p53.

artículo científico publicado en 2016

Co-consumption of methanol and succinate by Methylobacterium extorquens AM1.

artículo científico publicado en 2012

Combined transcriptomics-metabolomics profiling of the heat shock response in the hyperthermophilic archaeon Pyrococcus furiosus

scientific article published on 14 November 2018

Combining metabolomics and gene expression analysis reveals that propionyl- and butyryl-carnitines are involved in late stages of arbuscular mycorrhizal symbiosis.

artículo científico publicado en 2013

Comparative analysis of 13C-enriched metabolites released in the medium of cerebellar and cortical astrocytes incubated with [1-13C]glucose

artículo científico publicado en 1995

Control and regulation of acetate overflow in Escherichia coli

artículo científico publicado en 2021

Correction of MS data for naturally occurring isotopes in isotope labelling experiments.

artículo científico publicado en 2014

Cyclic organization of the carbohydrate metabolism in Sinorhizobium meliloti

scientific article published on 01 October 1999

Cytosolic NADPH homeostasis in glucose-starved procyclic Trypanosoma brucei relies on malic enzyme and the pentose phosphate pathway fed by gluconeogenic flux.

artículo científico publicado en 2013

Demonstration of the ethylmalonyl-CoA pathway by using 13C metabolomics.

scholarly article

Determination of carbon labeling distribution of intracellular metabolites from single fragment ions by ion chromatography tandem mass spectrometry.

artículo científico publicado en 2006

Developmental stage dependent metabolic regulation during meiotic differentiation in budding yeast.

artículo científico publicado en 2014

Differential quantitative proteome analysis of Escherichia coli grown on acetate versus glucose.

artículo científico

E4F1 controls a transcriptional program essential for pyruvate dehydrogenase activity

artículo científico publicado en 2016

Engineering Escherichia coli for methanol conversion

artículo científico publicado en 2015

Exploring the Glucose Fluxotype of the E. coli y-ome Using High-Resolution Fluxomics

artículo científico publicado en 2021

Fast spatially encoded 3D NMR strategies for (13)C-based metabolic flux analysis

artículo científico publicado en 2013

FindPath: a Matlab solution for in silico design of synthetic metabolic pathways.

artículo científico publicado en 2014

Functional analysis of isoprenoid precursors biosynthesis by quantitative metabolomics and isotopologue profiling

scientific article published on 21 August 2019

Functional characterization of a gene locus from an uncultured gut Bacteroides conferring xylo-oligosaccharides utilization to Escherichia coli.

artículo científico publicado en 2016

Functional genomics of the muscle response to restraint and transport in chickens.

artículo científico publicado en 2011

Genome-scale reconstruction and system level investigation of the metabolic network of Methylobacterium extorquens AM1.

artículo científico publicado en 2011

Gluconeogenesis is essential for trypanosome development in the tsetse fly vector

artículo científico publicado en 2018

Glucose and glutamine metabolism in C6 glioma cells studied by carbon 13 NMR.

artículo científico publicado en 1996

Glutathione, but not glutamine, is detected in 13C-NMR spectra of perchloric acid extracts from C6 glioma cells.

artículo científico publicado en 1993

Glycerol supports growth of the Trypanosoma brucei bloodstream forms in the absence of glucose: Analysis of metabolic adaptations on glycerol-rich conditions

artículo científico publicado en 2018

Glycerol suppresses glucose consumption in trypanosomes through metabolic contest

artículo científico publicado en 2021

High mTORC1 activity drives glycolysis addiction and sensitivity to G6PD inhibition in acute myeloid leukemia cells

artículo científico publicado en 2017

Identification of a fourth formate dehydrogenase in Methylobacterium extorquens AM1 and confirmation of the essential role of formate oxidation in methylotrophy.

artículo científico

Impact of kinetic isotope effects in isotopic studies of metabolic systems.

artículo científico publicado en 2015

Improved Isotopic Profiling by Pure Shift Heteronuclear 2D J-Resolved NMR Spectroscopy

artículo científico publicado en 2018

Improved riboflavin production with Ashbya gossypii from vegetable oil based on 13C metabolic network analysis with combined labeling analysis by GC/MS, LC/MS, 1D, and 2D NMR.

artículo científico publicado en 2018

In vivo 13C NMR determines metabolic fluxes and steady state in linseed embryos

scientific article published on 30 May 2007

In vivo 13C-NMR studies of polymer synthesis in rhizobium meliloti M5N1 strain

In-cell NMR: from metabolites to macromolecules

artículo científico publicado en 2018

IsoCor: correcting MS data in isotope labeling experiments.

artículo científico publicado en 2012

Isocitrate dehydrogenase 1 mutations prime the all-trans retinoic acid myeloid differentiation pathway in acute myeloid leukemia.

artículo científico publicado en 2016

Isotopic profiling of 13C-labeled biological samples by two-dimensional heteronuclear J-resolved nuclear magnetic resonance spectroscopy ⬇️

artículo científico publicado el 29 de mayo de 2012

Isotopic studies of metabolic systems by mass spectrometry: using Pascal's triangle to produce biological standards with fully controlled labeling patterns

artículo científico publicado en 2014

Lysine production from the sugar alcohol mannitol: Design of the cell factory Corynebacterium glutamicum SEA-3 through integrated analysis and engineering of metabolic pathway fluxes

artículo científico publicado en 2018

Magnetic resonance spectroscopy and metabolism. Applications of proton and 13C NMR to the study of glutamate metabolism in cultured glial cells and human brain in vivo.

artículo científico publicado en 1991

Mechanism of gluconate synthesis in Rhizobium meliloti by using in vivo NMR

scientific article published on 01 August 1997

Metabolic flux analysis in Ashbya gossypii using C-labeled yeast extract: industrial riboflavin production under complex nutrient conditions

article

Metabolic footprint of epiphytic bacteria on Arabidopsis thaliana leaves

artículo científico publicado en 2015

Metabolite profiling of pea roots in response to phosphate availability.

artículo científico publicado en 2011

Mitochondrial energetic and AKT status mediate metabolic effects and apoptosis of metformin in human leukemic cells.

artículo científico publicado en 2013

Multilevel interaction of the DnaK/DnaJ(HSP70/HSP40) stress-responsive chaperone machine with the central metabolism.

artículo científico publicado en 2017

NMR-based fluxomics: quantitative 2D NMR methods for isotopomers analysis.

artículo científico publicado en 2007

Photobioreactor design for isotopic non‐stationary 13C‐metabolic flux analysis (INST 13C‐MFA) under photoautotrophic conditions ⬇️

artículo científico publicado el 27 de junio de 2012

Physiological and Molecular Timing of the Glucose to Acetate Transition in Escherichia coli

artículo científico publicado en 2013

Plasmid-encoded biosynthetic genes alleviate metabolic disadvantages while increasing glucose conversion to shikimate in an engineered Escherichia coli strain

artículo científico publicado en 2017

Procyclic trypanosomes recycle glucose catabolites and TCA cycle intermediates to stimulate growth in the presence of physiological amounts of proline

artículo científico publicado en 2021

Production of carbon-13-labeled cadaverine by engineered Corynebacterium glutamicum using carbon-13-labeled methanol as co-substrate.

artículo científico publicado en 2015

Quantitative metabolome analysis using liquid chromatography-high-resolution mass spectrometry.

artículo científico publicado en 2008

Quantitative metabolomics of the thermophilic methylotroph Bacillus methanolicus

artículo científico publicado en 2016

Recent advances in high-throughput 13C-fluxomics

artículo científico publicado en 2016

Relevance and isotopic assessment of hexose-6-phosphate recycling in micro-organisms

artículo científico publicado en 2000

Response of the central metabolism of Escherichia coli to modified expression of the gene encoding the glucose-6-phosphate dehydrogenase.

artículo científico publicado en 2007

Sampling for metabolome analysis of microorganisms.

artículo científico publicado en 2007

Sampling of intracellular metabolites for stationary and non-stationary (13)C metabolic flux analysis in Escherichia coli.

artículo científico publicado en 2014

ScalaFlux: A scalable approach to quantify fluxes in metabolic subnetworks

scientific article published on 14 April 2020

Stable Isotope Labeling Highlights Enhanced Fatty Acid and Lipid Metabolism in Human Acute Myeloid Leukemia

artículo científico publicado en 2018

Standard reporting requirements for biological samples in metabolomics experiments: microbial and in vitro biology experiments.

artículo científico publicado en 2007

Strigolactones stimulate arbuscular mycorrhizal fungi by activating mitochondria

artículo científico publicado en 2006

Synthesis of dextrans with controlled amounts of alpha-1,2 linkages using the transglucosidase GBD-CD2.

artículo científico publicado en 2009

Targeting MDM2-dependent serine metabolism as a therapeutic strategy for liposarcoma

artículo científico publicado en 2020

The Csr System Regulates Escherichia coli Fitness by Controlling Glycogen Accumulation and Energy Levels

artículo científico publicado en 2017

The carbon storage regulator (Csr) system exerts a nutrient-specific control over central metabolism in Escherichia coli strain Nissle 1917.

artículo científico publicado en 2013

The ethylmalonyl-CoA pathway is used in place of the glyoxylate cycle by Methylobacterium extorquens AM1 during growth on acetate.

artículo científico publicado en 2011

The post-transcriptional regulatory system CSR controls the balance of metabolic pools in upper glycolysis of Escherichia coli.

artículo científico publicado en 2016

Theoretical Basis for Dynamic Label Propagation in Stationary Metabolic Networks under Step and Periodic Inputs.

artículo científico publicado en 2015

Transketolase in Trypanosoma brucei

artículo científico publicado en 2011

UFJCOSY: a fast 3D NMR method for measuring isotopic enrichments in complex samples

artículo científico publicado en 2012

Ultrafast quantitative 2D NMR: an efficient tool for the measurement of specific isotopic enrichments in complex biological mixtures.

artículo científico publicado en 2011

[1-13C]glucose metabolism in rat cerebellar granule cells and astrocytes in primary culture. Evaluation of flux parameters by 13C- and 1H-NMR spectroscopy

artículo científico publicado en 1993

Lista de obras de J C Portais

A methodology for the validation of isotopic analyses by mass spectrometry in stable-isotope labelling experiments

A novel platform for automated high-throughput fluxome profiling of metabolic variants.

Ablation of succinate production from glucose metabolism in the procyclic trypanosomes induces metabolic switches to the glycerol 3-phosphate/dihydroxyacetone phosphate shuttle and to proline metabolism.

Acetate Exposure Determines the Diauxic Behavior of Escherichia coli during the Glucose-Acetate Transition.

Acetate fluxes in Escherichia coli are determined by the thermodynamic control of the Pta-AckA pathway.

An optimization method for untargeted MS-based isotopic tracing investigations of metabolism

Application of 2D-TOCSY NMR to the measurement of specific(13C-enrichments in complex mixtures of 13C-labeled metabolites.

Bio-based succinate from sucrose: High-resolution 13C metabolic flux analysis and metabolic engineering of the rumen bacterium Basfia succiniciproducens.

Biofilm microenvironment induces a widespread adaptive amino-acid fermentation pathway conferring strong fitness advantage in Escherichia coli.

Carbohydrate cycling in micro-organisms: what can (13)C-NMR tell us?

Chemotherapy-Resistant Human Acute Myeloid Leukemia Cells Are Not Enriched for Leukemic Stem Cells but Require Oxidative Metabolism

Chromatin-Bound MDM2 Regulates Serine Metabolism and Redox Homeostasis Independently of p53.

Co-consumption of methanol and succinate by Methylobacterium extorquens AM1.

Combined transcriptomics-metabolomics profiling of the heat shock response in the hyperthermophilic archaeon Pyrococcus furiosus

Combining metabolomics and gene expression analysis reveals that propionyl- and butyryl-carnitines are involved in late stages of arbuscular mycorrhizal symbiosis.

Comparative analysis of 13C-enriched metabolites released in the medium of cerebellar and cortical astrocytes incubated with [1-13C]glucose

Control and regulation of acetate overflow in Escherichia coli

Correction of MS data for naturally occurring isotopes in isotope labelling experiments.

Cyclic organization of the carbohydrate metabolism in Sinorhizobium meliloti

Cytosolic NADPH homeostasis in glucose-starved procyclic Trypanosoma brucei relies on malic enzyme and the pentose phosphate pathway fed by gluconeogenic flux.

Demonstration of the ethylmalonyl-CoA pathway by using 13C metabolomics.

Determination of carbon labeling distribution of intracellular metabolites from single fragment ions by ion chromatography tandem mass spectrometry.

Developmental stage dependent metabolic regulation during meiotic differentiation in budding yeast.

Differential quantitative proteome analysis of Escherichia coli grown on acetate versus glucose.

E4F1 controls a transcriptional program essential for pyruvate dehydrogenase activity

Engineering Escherichia coli for methanol conversion

Exploring the Glucose Fluxotype of the E. coli y-ome Using High-Resolution Fluxomics

Fast spatially encoded 3D NMR strategies for (13)C-based metabolic flux analysis

FindPath: a Matlab solution for in silico design of synthetic metabolic pathways.

Functional analysis of isoprenoid precursors biosynthesis by quantitative metabolomics and isotopologue profiling

Functional characterization of a gene locus from an uncultured gut Bacteroides conferring xylo-oligosaccharides utilization to Escherichia coli.

Functional genomics of the muscle response to restraint and transport in chickens.

Genome-scale reconstruction and system level investigation of the metabolic network of Methylobacterium extorquens AM1.

Gluconeogenesis is essential for trypanosome development in the tsetse fly vector

Glucose and glutamine metabolism in C6 glioma cells studied by carbon 13 NMR.

Glutathione, but not glutamine, is detected in 13C-NMR spectra of perchloric acid extracts from C6 glioma cells.

Glycerol supports growth of the Trypanosoma brucei bloodstream forms in the absence of glucose: Analysis of metabolic adaptations on glycerol-rich conditions

Glycerol suppresses glucose consumption in trypanosomes through metabolic contest

High mTORC1 activity drives glycolysis addiction and sensitivity to G6PD inhibition in acute myeloid leukemia cells

Identification of a fourth formate dehydrogenase in Methylobacterium extorquens AM1 and confirmation of the essential role of formate oxidation in methylotrophy.

Impact of kinetic isotope effects in isotopic studies of metabolic systems.

Improved Isotopic Profiling by Pure Shift Heteronuclear 2D J-Resolved NMR Spectroscopy

Improved riboflavin production with Ashbya gossypii from vegetable oil based on 13C metabolic network analysis with combined labeling analysis by GC/MS, LC/MS, 1D, and 2D NMR.

In vivo 13C NMR determines metabolic fluxes and steady state in linseed embryos

In vivo 13C-NMR studies of polymer synthesis in rhizobium meliloti M5N1 strain

In-cell NMR: from metabolites to macromolecules

IsoCor: correcting MS data in isotope labeling experiments.

Isocitrate dehydrogenase 1 mutations prime the all-trans retinoic acid myeloid differentiation pathway in acute myeloid leukemia.

Isotopic profiling of 13C-labeled biological samples by two-dimensional heteronuclear J-resolved nuclear magnetic resonance spectroscopy ⬇️

Isotopic studies of metabolic systems by mass spectrometry: using Pascal's triangle to produce biological standards with fully controlled labeling patterns

Lysine production from the sugar alcohol mannitol: Design of the cell factory Corynebacterium glutamicum SEA-3 through integrated analysis and engineering of metabolic pathway fluxes

Magnetic resonance spectroscopy and metabolism. Applications of proton and 13C NMR to the study of glutamate metabolism in cultured glial cells and human brain in vivo.

Mechanism of gluconate synthesis in Rhizobium meliloti by using in vivo NMR

Metabolic flux analysis in Ashbya gossypii using C-labeled yeast extract: industrial riboflavin production under complex nutrient conditions

Metabolic footprint of epiphytic bacteria on Arabidopsis thaliana leaves

Metabolite profiling of pea roots in response to phosphate availability.

Mitochondrial energetic and AKT status mediate metabolic effects and apoptosis of metformin in human leukemic cells.

Multilevel interaction of the DnaK/DnaJ(HSP70/HSP40) stress-responsive chaperone machine with the central metabolism.

NMR-based fluxomics: quantitative 2D NMR methods for isotopomers analysis.

Photobioreactor design for isotopic non‐stationary 13C‐metabolic flux analysis (INST 13C‐MFA) under photoautotrophic conditions ⬇️

Physiological and Molecular Timing of the Glucose to Acetate Transition in Escherichia coli

Plasmid-encoded biosynthetic genes alleviate metabolic disadvantages while increasing glucose conversion to shikimate in an engineered Escherichia coli strain

Procyclic trypanosomes recycle glucose catabolites and TCA cycle intermediates to stimulate growth in the presence of physiological amounts of proline

Production of carbon-13-labeled cadaverine by engineered Corynebacterium glutamicum using carbon-13-labeled methanol as co-substrate.

Quantitative metabolome analysis using liquid chromatography-high-resolution mass spectrometry.

Quantitative metabolomics of the thermophilic methylotroph Bacillus methanolicus

Recent advances in high-throughput 13C-fluxomics

Relevance and isotopic assessment of hexose-6-phosphate recycling in micro-organisms

Response of the central metabolism of Escherichia coli to modified expression of the gene encoding the glucose-6-phosphate dehydrogenase.

Sampling for metabolome analysis of microorganisms.

Sampling of intracellular metabolites for stationary and non-stationary (13)C metabolic flux analysis in Escherichia coli.

ScalaFlux: A scalable approach to quantify fluxes in metabolic subnetworks

Stable Isotope Labeling Highlights Enhanced Fatty Acid and Lipid Metabolism in Human Acute Myeloid Leukemia

Standard reporting requirements for biological samples in metabolomics experiments: microbial and in vitro biology experiments.

Strigolactones stimulate arbuscular mycorrhizal fungi by activating mitochondria

Synthesis of dextrans with controlled amounts of alpha-1,2 linkages using the transglucosidase GBD-CD2.

Targeting MDM2-dependent serine metabolism as a therapeutic strategy for liposarcoma

The Csr System Regulates Escherichia coli Fitness by Controlling Glycogen Accumulation and Energy Levels

The carbon storage regulator (Csr) system exerts a nutrient-specific control over central metabolism in Escherichia coli strain Nissle 1917.