Lista de obras - J. Julian Blow - Dominio Público Uruguay

A Role for Dormant Origins in Tumor Suppression ⬇️

artículo científico publicado el 4 de marzo de 2011

A Xenopus Dbf4 homolog is required for Cdc7 chromatin binding and DNA replication

artículo científico publicado en 2004

A model for DNA replication showing how dormant origins safeguard against replication fork failure.

artículo científico publicado en 2009

A new role for Ran in ensuring precise duplication of chromosomal DNA.

artículo científico publicado en 2003

A role for the nuclear envelope in controlling DNA replication within the cell cycle ⬇️

artículo científico publicado el 7 de abril de 1988

Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5.

artículo científico publicado en 1997

Biphasic chromatin binding of histone chaperone FACT during eukaryotic chromatin DNA replication.

artículo científico publicado en 2011

Both Chromosome Decondensation and Condensation Are Dependent on DNA Replication in C. elegans Embryos.

artículo científico publicado en 2015

Both cyclin A and cyclin E have S-phase promoting (SPF) activity in Xenopus egg extracts

scientific article published on 01 June 1996

Buffered Qualitative Stability explains the robustness and evolvability of transcriptional networks.

artículo científico publicado en 2014

Cdt1 downregulation by proteolysis and geminin inhibition prevents DNA re-replication in Xenopus

artículo científico publicado en 2004

Cell Cycle Synchronization in Xenopus Egg Extracts.

artículo científico publicado en 2016

Cell cycle control of DNA replication by p34cdc2

artículo científico publicado el 1 de agosto de 1991

Characterization of the Xenopus replication licensing system.

artículo científico publicado en 1997

Chk1 inhibits replication factory activation but allows dormant origin firing in existing factories. ⬇️

artículo científico publicado en 2010

Chromatin proteins involved in the initiation of DNA replication.

artículo científico publicado en 1997

Chromosome replication: from ORC to fork

artículo científico publicado en 2001

Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing

artículo científico publicado en 2016

Cip1 blocks the initiation of DNA replication in Xenopus extracts by inhibition of cyclin-dependent kinases

scientific article published on 01 October 1994

Clusters, factories and domains: The complex structure of S-phase comes into focus.

artículo científico publicado en 2010

Combinatorial regulation of meiotic holliday junction resolution in C. elegans by HIM-6 (BLM) helicase, SLX-4, and the SLX-1, MUS-81 and XPF-1 nucleases

artículo científico publicado en 2013

DNA replication initiates at multiple sites on plasmid DNA in Xenopus egg extracts.

artículo científico publicado en 1992

DNA replication licensing factor ⬇️

artículo científico publicado el 1 de enero de 1996

DNA replication: stable driving prevents fatal smashes

artículo científico publicado en 2001

Defects in the origin licensing checkpoint stresses cells exiting G0

scientific article published on 11 June 2019

Deregulated origin licensing leads to chromosomal breaks by rereplication of a gapped DNA template

artículo científico publicado en 2013

Deregulated replication licensing causes DNA fragmentation consistent with head-to-tail fork collision.

artículo científico publicado en 2006

Development of BromoTag: A “Bump-and-Hole”–PROTAC System to Induce Potent, Rapid, and Selective Degradation of Tagged Target Proteins

scientific article published on 17 October 2021

Direct non transcriptional role of NF-Y in DNA replication.

artículo científico publicado en 2015

Dormant Origins, the Licensing Checkpoint, and the Response to Replicative Stresses ⬇️

artículo científico publicado el 1 de octubre de 2012

Dormant origins licensed by excess Mcm2-7 are required for human cells to survive replicative stress.

artículo científico publicado en 2007

Dynamic SUMO modification regulates mitotic chromosome assembly and cell cycle progression in Caenorhabditis elegans

artículo científico publicado en 2014

Dynamic interactions of high Cdt1 and geminin levels regulate S phase in early Xenopus embryos.

artículo científico publicado en 2011

ELYS/MEL-28 chromatin association coordinates nuclear pore complex assembly and replication licensing

artículo científico publicado en 2007

Editorial overview

artículo científico publicado en 2000

Erratum: Dynamic SUMO modification regulates mitotic chromosome assembly and cell cycle progression in Caenorhabditis elegans.

artículo científico publicado en 2015

Evidence for a mammalian late-G1 phase inhibitor of replication licensing distinct from geminin or Cdk activity ⬇️

artículo científico publicado el 1 de septiembre de 2011

Excess Mcm2-7 license dormant origins of replication that can be used under conditions of replicative stress.

artículo científico publicado en 2006

Functional domains of the Xenopus replication licensing factor Cdt1

artículo científico publicado en 2005

Geminin becomes activated as an inhibitor of Cdt1/RLF-B following nuclear import.

artículo científico publicado en 2002

Histone H4K20 methylation mediated chromatin compaction threshold ensures genome integrity by limiting DNA replication licensing

scientific article published in Nature Communications

Inevitability and containment of replication errors for eukaryotic genome lengths spanning megabase to gigabase.

artículo científico publicado en 2016

Interaction between the origin recognition complex and the replication licensing system in Xenopus.

artículo científico publicado en 1996

Lgr5+ intestinal stem cells reside in an unlicensed G1 phase.

artículo científico publicado en 2018

Many strands converge

artículo científico publicado en 1987

Negative regulation of geminin by CDK-dependent ubiquitination controls replication licensing.

artículo científico publicado en 2004

Non-proteolytic inactivation of geminin requires CDK-dependent ubiquitination.

artículo científico publicado en 2004

Nuclear structure and the control of DNA replication in the Xenopus embryo

scientific article published on 01 January 1989

Nuclei act as independent and integrated units of replication in a Xenopus cell-free DNA replication system.

artículo científico publicado en 1987

Optimisation of the two-dimensional gel electrophoresis protocol using the Taguchi approach

artículo científico publicado en 2004

PHD1 links cell-cycle progression to oxygen sensing through hydroxylation of the centrosomal protein Cep192

artículo científico publicado en 2013

PTIP/Swift is required for efficient PCNA ubiquitination in response to DNA damage

scientific journal article

Preventing re-replication of DNA in a single cell cycle: evidence for a replication licensing factor.

artículo científico publicado en 1993

Preventing re-replication of chromosomal DNA.

artículo científico publicado en 2005

Quaternary structure of the human Cdt1-Geminin complex regulates DNA replication licensing

artículo científico publicado en 2009

Rapid induction of pluripotency genes after exposure of human somatic cells to mouse ES cell extracts.

artículo científico publicado en 2008

Re-replication induced by geminin depletion occurs from G2 and is enhanced by checkpoint activation.

artículo científico publicado en 2012

Reconstitution of licensed replication origins on Xenopus sperm nuclei using purified proteins ⬇️

artículo científico publicado el 5 de diciembre de 2001

Replication factory activation can be decoupled from the replication timing program by modulating Cdk levels.

artículo científico publicado en 2010

Replication forks, chromatin loops and dormant replication origins

artículo científico publicado en 2008

Replication occurs at discrete foci spaced throughout nuclei replicating in vitro.

artículo científico publicado en 1989

Replisome stall events have shaped the distribution of replication origins in the genomes of yeasts

artículo científico publicado en 2013

Repression of origin assembly in metaphase depends on inhibition of RLF-B/Cdt1 by geminin

artículo científico publicado en 2001

Reversal of DDK-Mediated MCM Phosphorylation by Rif1-PP1 Regulates Replication Initiation and Replisome Stability Independently of ATR/Chk1. ⬇️

artículo científico publicado en 2017

Site-specific initiation of DNA replication in metazoan chromosomes and the role of nuclear organization

artículo científico publicado en 1993

Stochastic association of neighboring replicons creates replication factories in budding yeast.

artículo científico publicado en 2013

The Anthelmintic Drug Niclosamide and its Analogues Activate the Parkinson's Disease Associated Protein Kinase PINK1.

artículo científico publicado en 2017

The DNA replication licensing system

artículo científico publicado el 1 de enero de 1997

The Geminin and Idas Coiled Coils Preferentially Form a Heterodimer That Inhibits Geminin Function in DNA Replication Licensing

artículo científico publicado en 2013

The High-Affinity Interaction between ORC and DNA that Is Required for Replication Licensing Is Inhibited by 2-Arylquinolin-4-Amines

artículo científico publicado en 2017

The KRAB Zinc Finger Protein Roma/Zfp157 Is a Critical Regulator of Cell-Cycle Progression and Genomic Stability

artículo científico publicado en 2016

The RLF-B component of the replication licensing system is distinct from Cdc6 and functions after Cdc6 binds to chromatin

artículo científico publicado en 1999

The RLF-M component of the replication licensing system forms complexes containing all six MCM/P1 polypeptides ⬇️

artículo científico publicado el 2 de junio de 1997

The SMC-5/6 Complex and the HIM-6 (BLM) Helicase Synergistically Promote Meiotic Recombination Intermediate Processing and Chromosome Maturation during Caenorhabditis elegans Meiosis

artículo científico publicado en 2016

The Xenopus origin recognition complex is essential for DNA replication and MCM binding to chromatin

scientific article published on 01 November 1996

The contribution of dormant origins to genome stability: from cell biology to human genetics.

artículo científico publicado en 2014

The dynamics of replication licensing in live Caenorhabditis elegans embryos.

artículo científico publicado en 2012

The licensing checkpoint opens up.

artículo científico publicado en 2009

The origin of CDK regulation

artículo científico publicado en 2001

The regulation of chromosome replication

artículo científico publicado el 1 de junio de 1992

The replication capacity of intact mammalian nuclei in Xenopus egg extracts declines with quiescence, but the residual DNA synthesis is independent of Xenopus MCM proteins.

artículo científico publicado en 2000

The replication licensing system ⬇️

artículo científico publicado el 1 de agosto de 1998

The role of DDK and Treslin–MTBP in coordinating replication licensing and pre-initiation complex formation

scientific article published on 27 October 2021

The role of cyclin synthesis, modification and destruction in the control of cell division.

artículo científico publicado en 1989

The role of the replication licensing system in cell proliferation and cancer ⬇️

artículo científico publicado el 1 de enero de 2003

Translation of cyclin mRNA is necessary for extracts of activated xenopus eggs to enter mitosis.

artículo científico publicado en 1989

Ubiquitinated Fancd2 recruits Fan1 to stalled replication forks to prevent genome instability

artículo científico publicado en 2016

Unreplicated DNA remaining from unperturbed S phases passes through mitosis for resolution in daughter cells

artículo científico publicado en 2016

Xenopus Cdc7 executes its essential function early in S phase and is counteracted by checkpoint-regulated protein phosphatase 1.

artículo científico publicado en 2014

Xenopus Mcm10 is a CDK-substrate required for replication fork stability.

artículo científico publicado en 2016

Xenopus cell-free extracts and their contribution to the study of DNA replication and other complex biological processes

artículo científico publicado en 2016

Lista de obras de J. Julian Blow

A Role for Dormant Origins in Tumor Suppression ⬇️

A Xenopus Dbf4 homolog is required for Cdc7 chromatin binding and DNA replication

A model for DNA replication showing how dormant origins safeguard against replication fork failure.

A new role for Ran in ensuring precise duplication of chromosomal DNA.

A role for the nuclear envelope in controlling DNA replication within the cell cycle ⬇️

Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5.

Biphasic chromatin binding of histone chaperone FACT during eukaryotic chromatin DNA replication.

Both Chromosome Decondensation and Condensation Are Dependent on DNA Replication in C. elegans Embryos.

Both cyclin A and cyclin E have S-phase promoting (SPF) activity in Xenopus egg extracts

Buffered Qualitative Stability explains the robustness and evolvability of transcriptional networks.

Cdt1 downregulation by proteolysis and geminin inhibition prevents DNA re-replication in Xenopus

Cell Cycle Synchronization in Xenopus Egg Extracts.

Cell cycle control of DNA replication by p34cdc2

Characterization of the Xenopus replication licensing system.

Chk1 inhibits replication factory activation but allows dormant origin firing in existing factories. ⬇️

Chromatin proteins involved in the initiation of DNA replication.

Chromosome replication: from ORC to fork

Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing

Cip1 blocks the initiation of DNA replication in Xenopus extracts by inhibition of cyclin-dependent kinases

Clusters, factories and domains: The complex structure of S-phase comes into focus.

Combinatorial regulation of meiotic holliday junction resolution in C. elegans by HIM-6 (BLM) helicase, SLX-4, and the SLX-1, MUS-81 and XPF-1 nucleases

DNA replication initiates at multiple sites on plasmid DNA in Xenopus egg extracts.

DNA replication licensing factor ⬇️

DNA replication: stable driving prevents fatal smashes

Defects in the origin licensing checkpoint stresses cells exiting G0

Deregulated origin licensing leads to chromosomal breaks by rereplication of a gapped DNA template

Deregulated replication licensing causes DNA fragmentation consistent with head-to-tail fork collision.

Development of BromoTag: A “Bump-and-Hole”–PROTAC System to Induce Potent, Rapid, and Selective Degradation of Tagged Target Proteins

Direct non transcriptional role of NF-Y in DNA replication.

Dormant Origins, the Licensing Checkpoint, and the Response to Replicative Stresses ⬇️

Dormant origins licensed by excess Mcm2-7 are required for human cells to survive replicative stress.

Dynamic SUMO modification regulates mitotic chromosome assembly and cell cycle progression in Caenorhabditis elegans

Dynamic interactions of high Cdt1 and geminin levels regulate S phase in early Xenopus embryos.

ELYS/MEL-28 chromatin association coordinates nuclear pore complex assembly and replication licensing

Editorial overview

Erratum: Dynamic SUMO modification regulates mitotic chromosome assembly and cell cycle progression in Caenorhabditis elegans.

Evidence for a mammalian late-G1 phase inhibitor of replication licensing distinct from geminin or Cdk activity ⬇️

Excess Mcm2-7 license dormant origins of replication that can be used under conditions of replicative stress.

Functional domains of the Xenopus replication licensing factor Cdt1

Geminin becomes activated as an inhibitor of Cdt1/RLF-B following nuclear import.

Histone H4K20 methylation mediated chromatin compaction threshold ensures genome integrity by limiting DNA replication licensing

Inevitability and containment of replication errors for eukaryotic genome lengths spanning megabase to gigabase.

Interaction between the origin recognition complex and the replication licensing system in Xenopus.

Lgr5+ intestinal stem cells reside in an unlicensed G1 phase.

Many strands converge

Negative regulation of geminin by CDK-dependent ubiquitination controls replication licensing.

Non-proteolytic inactivation of geminin requires CDK-dependent ubiquitination.

Nuclear structure and the control of DNA replication in the Xenopus embryo

Nuclei act as independent and integrated units of replication in a Xenopus cell-free DNA replication system.

Optimisation of the two-dimensional gel electrophoresis protocol using the Taguchi approach

PHD1 links cell-cycle progression to oxygen sensing through hydroxylation of the centrosomal protein Cep192

PTIP/Swift is required for efficient PCNA ubiquitination in response to DNA damage

Preventing re-replication of DNA in a single cell cycle: evidence for a replication licensing factor.

Preventing re-replication of chromosomal DNA.

Quaternary structure of the human Cdt1-Geminin complex regulates DNA replication licensing

Rapid induction of pluripotency genes after exposure of human somatic cells to mouse ES cell extracts.

Re-replication induced by geminin depletion occurs from G2 and is enhanced by checkpoint activation.

Reconstitution of licensed replication origins on Xenopus sperm nuclei using purified proteins ⬇️

Replication factory activation can be decoupled from the replication timing program by modulating Cdk levels.

Replication forks, chromatin loops and dormant replication origins

Replication occurs at discrete foci spaced throughout nuclei replicating in vitro.

Replisome stall events have shaped the distribution of replication origins in the genomes of yeasts

Repression of origin assembly in metaphase depends on inhibition of RLF-B/Cdt1 by geminin

Reversal of DDK-Mediated MCM Phosphorylation by Rif1-PP1 Regulates Replication Initiation and Replisome Stability Independently of ATR/Chk1. ⬇️

Site-specific initiation of DNA replication in metazoan chromosomes and the role of nuclear organization

Stochastic association of neighboring replicons creates replication factories in budding yeast.

The Anthelmintic Drug Niclosamide and its Analogues Activate the Parkinson's Disease Associated Protein Kinase PINK1.

The DNA replication licensing system

The Geminin and Idas Coiled Coils Preferentially Form a Heterodimer That Inhibits Geminin Function in DNA Replication Licensing

The High-Affinity Interaction between ORC and DNA that Is Required for Replication Licensing Is Inhibited by 2-Arylquinolin-4-Amines

The KRAB Zinc Finger Protein Roma/Zfp157 Is a Critical Regulator of Cell-Cycle Progression and Genomic Stability

The RLF-B component of the replication licensing system is distinct from Cdc6 and functions after Cdc6 binds to chromatin

The RLF-M component of the replication licensing system forms complexes containing all six MCM/P1 polypeptides ⬇️

The SMC-5/6 Complex and the HIM-6 (BLM) Helicase Synergistically Promote Meiotic Recombination Intermediate Processing and Chromosome Maturation during Caenorhabditis elegans Meiosis

The Xenopus origin recognition complex is essential for DNA replication and MCM binding to chromatin

The contribution of dormant origins to genome stability: from cell biology to human genetics.

The dynamics of replication licensing in live Caenorhabditis elegans embryos.

The licensing checkpoint opens up.

The origin of CDK regulation