Lista de obras - K J Lumb - Dominio Público Uruguay

1H nuclear magnetic resonance studies of the interaction of urea with hen lysozyme. Origins of the conformational change induced in hen lysozyme by N-acetylglucosamine oligosaccharides

artículo científico publicado el 5 de septiembre de 1992

A buried polar interaction imparts structural uniqueness in a designed heterodimeric coiled coil

scientific article published on 01 July 1995

A long-acting selective neuropeptide Y2 receptor PEGylated peptide agonist reduces food intake in mice

artículo científico publicado en 2007

Complementation of buried lysine and surface polar residues in a designed heterodimeric coiled coil.

artículo científico publicado en 2002

Detection of Small-Molecule Aggregation with High-Throughput Microplate Biophysical Methods

artículo científico publicado en 2020

Discovery of a 5H-Benzo[4,5]cyclohepta[1,2-b]pyridin-5-one (MK-2461) Inhibitor of c-Met Kinase for the Treatment of Cancer ⬇️

artículo científico publicado el 24 de mayo de 2011

Effects of macromolecular crowding on the intrinsically disordered proteins c-Fos and p27(Kip1)

artículo científico publicado en 2001

Electrostatic contribution of phosphorylation to the stability of the CREB-CBP activator-coactivator complex

artículo científico publicado en 1999

Expression, purification and crystallization of human prolylcarboxypeptidase

artículo científico publicado en 2010

Formation of a hydrophobic cluster in denatured bovine pancreatic trypsin inhibitor.

artículo científico publicado en 1994

Generation and characterization of a monoclonal IgG antibody to polyethylene glycol

artículo científico publicado en 2007

High-throughput screening by mass spectrometry: comparison with the scintillation proximity assay with a focused-file screen of AKT1/PKB alpha.

artículo científico publicado en 2007

Identification of selective neuropeptide Y2 peptide agonists.

artículo científico publicado en 2006

Insights into activity and inhibition from the crystal structure of human O-GlcNAcase.

artículo científico publicado en 2017

Integration of Affinity Selection-Mass Spectrometry and Functional Cell-Based Assays to Rapidly Triage Druggable Target Space within the NF-κB Pathway.

artículo científico publicado en 2016

Intrinsic structural disorder and sequence features of the cell cycle inhibitor p57Kip2

scientific journal article

Intrinsic structural disorder of the C-terminal activation domain from the bZIP transcription factor Fos

scientific journal article

KIX-Mediated Assembly of the CBP−CREB−HTLV-1 Tax Coactivator−Activator Complex ⬇️

artículo científico publicado el 4 de noviembre de 2003

Measurement of interhelical electrostatic interactions in the GCN4 leucine zipper

artículo científico publicado en 1995

Mechanism of action of the cell-division inhibitor PC190723: modulation of FtsZ assembly cooperativity.

artículo científico publicado en 2012

Molecular recognition of the human coactivator CBP by the HIV-1 transcriptional activator Tat

artículo científico publicado en 2003

NMR mapping of the HIV-1 Tat interaction surface of the KIX domain of the human coactivator CBP

scientific article published on 01 February 2004

Peptide 'Velcro': design of a heterodimeric coiled coil.

artículo científico publicado en 1993

Random-coil chemical shifts of phosphorylated amino acids.

artículo científico publicado en 1999

Reevaluation of transcriptional regulation by TATA-binding protein oligomerization: predominance of monomers

artículo científico publicado en 2000

Response: how much solar radiation do clouds absorb?

Restoring methicillin-resistant Staphylococcus aureus susceptibility to β-lactam antibiotics

artículo científico publicado en 2012

Structural Basis for Selective Small Molecule Kinase Inhibition of Activated c-Met

artículo científico publicado en 2011

Structural Basis of Human p70 Ribosomal S6 Kinase-1 Regulation by Activation Loop Phosphorylation

artículo científico publicado en 2010

Structural Basis of Small-Molecule Aggregate Induced Inhibition of a Protein-Protein Interaction.

artículo científico publicado en 2017

Structural basis for the cooperative allosteric activation of the free fatty acid receptor GPR40.

artículo científico publicado en 2017

Structural characterization of nonactive site, TrkA-selective kinase inhibitors.

artículo científico publicado en 2016

Structural definition and substrate specificity of the S28 protease family: the crystal structure of human prolylcarboxypeptidase

artículo científico publicado en 2010

Structurally distinct modes of recognition of the KIX domain of CBP by Jun and CREB.

artículo científico publicado en 2002

Structure and Function of the Hypertension Variant A486V of G Protein-coupled Receptor Kinase 4

artículo científico publicado en 2015

Structure of the Bacterial Deacetylase LpxC Bound to the Nucleotide Reaction Product Reveals Mechanisms of Oxyanion Stabilization and Proton Transfer

artículo científico publicado en 2013

Structures of kibdelomycin bound to Staphylococcus aureus GyrB and ParE showed a novel U-shaped binding mode

artículo científico publicado en 2014

Subdomain folding of the coiled coil leucine zipper from the bZIP transcriptional activator GCN4

artículo científico publicado en 1994

Transcriptional activity of the TFIIA four-helix bundle in vivo

artículo científico publicado en 2001

Lista de obras de K J Lumb

1H nuclear magnetic resonance studies of the interaction of urea with hen lysozyme. Origins of the conformational change induced in hen lysozyme by N-acetylglucosamine oligosaccharides

A buried polar interaction imparts structural uniqueness in a designed heterodimeric coiled coil

A long-acting selective neuropeptide Y2 receptor PEGylated peptide agonist reduces food intake in mice

Complementation of buried lysine and surface polar residues in a designed heterodimeric coiled coil.

Detection of Small-Molecule Aggregation with High-Throughput Microplate Biophysical Methods

Discovery of a 5H-Benzo[4,5]cyclohepta[1,2-b]pyridin-5-one (MK-2461) Inhibitor of c-Met Kinase for the Treatment of Cancer ⬇️

Effects of macromolecular crowding on the intrinsically disordered proteins c-Fos and p27(Kip1)

Electrostatic contribution of phosphorylation to the stability of the CREB-CBP activator-coactivator complex

Expression, purification and crystallization of human prolylcarboxypeptidase

Formation of a hydrophobic cluster in denatured bovine pancreatic trypsin inhibitor.

Generation and characterization of a monoclonal IgG antibody to polyethylene glycol

High-throughput screening by mass spectrometry: comparison with the scintillation proximity assay with a focused-file screen of AKT1/PKB alpha.

Identification of selective neuropeptide Y2 peptide agonists.

Insights into activity and inhibition from the crystal structure of human O-GlcNAcase.

Integration of Affinity Selection-Mass Spectrometry and Functional Cell-Based Assays to Rapidly Triage Druggable Target Space within the NF-κB Pathway.

Intrinsic structural disorder and sequence features of the cell cycle inhibitor p57Kip2

Intrinsic structural disorder of the C-terminal activation domain from the bZIP transcription factor Fos

KIX-Mediated Assembly of the CBP−CREB−HTLV-1 Tax Coactivator−Activator Complex ⬇️

Measurement of interhelical electrostatic interactions in the GCN4 leucine zipper

Mechanism of action of the cell-division inhibitor PC190723: modulation of FtsZ assembly cooperativity.

Molecular recognition of the human coactivator CBP by the HIV-1 transcriptional activator Tat

NMR mapping of the HIV-1 Tat interaction surface of the KIX domain of the human coactivator CBP

Peptide 'Velcro': design of a heterodimeric coiled coil.

Random-coil chemical shifts of phosphorylated amino acids.

Reevaluation of transcriptional regulation by TATA-binding protein oligomerization: predominance of monomers

Response: how much solar radiation do clouds absorb?

Restoring methicillin-resistant Staphylococcus aureus susceptibility to β-lactam antibiotics

Structural Basis for Selective Small Molecule Kinase Inhibition of Activated c-Met

Structural Basis of Human p70 Ribosomal S6 Kinase-1 Regulation by Activation Loop Phosphorylation

Structural Basis of Small-Molecule Aggregate Induced Inhibition of a Protein-Protein Interaction.

Structural basis for the cooperative allosteric activation of the free fatty acid receptor GPR40.

Structural characterization of nonactive site, TrkA-selective kinase inhibitors.

Structural definition and substrate specificity of the S28 protease family: the crystal structure of human prolylcarboxypeptidase

Structurally distinct modes of recognition of the KIX domain of CBP by Jun and CREB.

Structure and Function of the Hypertension Variant A486V of G Protein-coupled Receptor Kinase 4

Structure of the Bacterial Deacetylase LpxC Bound to the Nucleotide Reaction Product Reveals Mechanisms of Oxyanion Stabilization and Proton Transfer

Structures of kibdelomycin bound to Staphylococcus aureus GyrB and ParE showed a novel U-shaped binding mode

Subdomain folding of the coiled coil leucine zipper from the bZIP transcriptional activator GCN4

Transcriptional activity of the TFIIA four-helix bundle in vivo