Lista de obras - L C Leite - Dominio Público Uruguay

A Bivalent Recombinant BCG Expressing the S1 Subunit of the Pertussis Toxin Induces a Polyfunctional CD4 T Cell Immune Response

scientific article published on 28 February 2019

A Combination of Recombinant Mycobacterium bovis BCG Strains Expressing Pneumococcal Proteins Induces Cellular and Humoral Immune Responses and Protects against Pneumococcal Colonization and Sepsis

artículo científico publicado en 2017

A protein chimera including PspA in fusion with PotD is protective against invasive pneumococcal infection and reduces nasopharyngeal colonization in mice.

artículo científico publicado en 2017

A quantitative view of the transcriptome of Schistosoma mansoni adult-worms using SAGE

artículo científico publicado en 2007

Addressing racial inequalities in a pandemic: data limitations and a call for critical analyses

scientific article published on 15 September 2020

Adjuvant activity of Mycobacterium bovis BCG expressing CRM197 on the immune response induced by BCG expressing tetanus toxin fragment C.

artículo científico publicado en 2004

Advocacy, partnership and political commitment for TB vaccine research

artículo científico publicado en 2016

Analysis of serum cross-reactivity and cross-protection elicited by immunization with DNA vaccines against Streptococcus pneumoniae expressing PspA fragments from different clades.

artículo científico publicado en 2002

Carbon-centered free radical formation during the metabolism of hydrazine derivatives by neutrophils

scientific article published on 01 May 1993

Characterization of phosphodiesterase-5 as a surface protein in the tegument of Schistosoma mansoni.

artículo científico publicado en 2009

Characterization of the snake venoms from seven Brazilian species of Bothrops by FPLC anion-exchange chromatography

artículo científico publicado en 1992

Combined effects of lactoferrin and lysozyme on Streptococcus pneumoniae killing

artículo científico publicado en 2015

Conjugation of PspA4Pro with Capsular Streptococcus pneumoniae Polysaccharide Serotype 14 Does Not Reduce the Induction of Cross-Reactive Antibodies

artículo científico

Conjugation of polysaccharide 6B from Streptococcus pneumoniae with pneumococcal surface protein A: PspA conformation and its effect on the immune response

artículo científico publicado en 2013

Construction of an unmarked recombinant BCG expressing a pertussis antigen by auxotrophic complementation: protection against Bordetella pertussis challenge in neonates.

artículo científico publicado en 2009

Contribution of hydrazines-derived alkyl radicals to cytotoxicity and transformation induced in normal c-myc-overexpressing mouse fibroblasts ⬇️

artículo científico publicado el 1 de enero de 1998

Current status and perspectives on protein-based pneumococcal vaccines

artículo científico

DNA strand scission by the carbon radical derived from 2-phenyl-ethylhydrazine metabolism.

artículo científico publicado en 1984

DNA vaccines expressing pneumococcal surface protein A (PspA) elicit protection levels comparable to recombinant protein

artículo científico publicado en 2006

Developing Countries Vaccine Manufacturers Network (DCVMN): engaging to step up for vaccine discovery and access. Meeting report 2012.

artículo científico publicado en 2013

Developing Countries Vaccine Manufacturers Network: doing good by making high-quality vaccines affordable for all.

artículo científico

Development of a whole cell pneumococcal vaccine: BPL inactivation, cGMP production, and stability.

artículo científico publicado en 2013

Enhancement of Th1 lung immunity induced by recombinant Mycobacterium bovis Bacillus Calmette-Guerin attenuates airway allergic disease

artículo científico publicado en 2009

Expression and characterization of cholera toxin B-pneumococcal surface adhesin A fusion protein in Escherichia coli: ability of CTB-PsaA to induce humoral immune response in mice

artículo científico publicado en 2004

Expression of Streptococcus pneumoniae antigens, PsaA (pneumococcal surface antigen A) and PspA (pneumococcal surface protein A) by Lactobacillus casei.

artículo científico publicado en 2003

First report of a dead giant squid (Architeuthis dux) from an operating seismic vessel

article by Luciana Leite et al published 1 July 2016 in Marine biodiversity records

Fusion proteins containing family 1 and family 2 PspA fragments elicit protection against Streptococcus pneumoniae that correlates with antibody-mediated enhancement of complement deposition.

artículo científico publicado en 2007

GMP-grade pneumococcal whole-cell vaccine injected subcutaneously protects mice from nasopharyngeal colonization and fatal aspiration-sepsis ⬇️

artículo científico publicado el 19 de septiembre de 2010

Genetic diversity of PspA types among nasopharyngeal isolates collected during an ongoing surveillance study of children in Brazil

artículo científico publicado en 2006

HFE Variants and the Expression of Iron-Related Proteins in Breast Cancer-Associated Lymphocytes and Macrophages

scientific article published on 27 December 2016

Hemoglobin-mediated oxidation of the carcinogen 1,2-dimethylhydrazine to methyl radicals

scientific article published on 01 November 1988

Humoral immune response of a pneumococcal conjugate vaccine: Capsular polysaccharide serotype 14—Lysine modified PspA

article

IL-17A and complement contribute to killing of pneumococci following immunization with a pneumococcal whole cell vaccine.

artículo científico publicado en 2017

Immunization of mice with single PspA fragments induces antibodies capable of mediating complement deposition on different pneumococcal strains and cross-protection.

artículo científico publicado en 2010

Immunization with tegument nucleotidases associated with a subcurative praziquantel treatment reduces worm burden following Schistosoma mansoni challenge.

artículo científico publicado en 2013

Induction of boosted immune response in mice by leptospiral surface proteins expressed in fusion with DnaK.

artículo científico publicado en 2014

Induction of neutralizing antibodies against diphtheria toxin by priming with recombinant Mycobacterium bovis BCG expressing CRM(197), a mutant diphtheria toxin.

artículo científico publicado en 2001

Induction of systemic and mucosal immune response and decrease in Streptococcus pneumoniae colonization by nasal inoculation of mice with recombinant lactic acid bacteria expressing pneumococcal surface antigen A.

artículo científico publicado en 2006

Mycobacterial codon optimization of the gene encoding the Sm14 antigen of Schistosoma mansoni in recombinant Mycobacterium bovis Bacille Calmette-Guérin enhances protein expression but not protection against cercarial challenge in mice.

artículo científico publicado en 2006

Nasal immunization of mice with Lactobacillus casei expressing the Pneumococcal Surface Protein A: induction of antibodies, complement deposition and partial protection against Streptococcus pneumoniae challenge

artículo científico publicado en 2008

Neonatal immunization with a single dose of recombinant BCG expressing subunit S1 from pertussis toxin induces complete protection against Bordetella pertussis intracerebral challenge

artículo científico publicado en 2007

New Recombinant Mycobacterium bovis BCG Expression Vectors: Improving Genetic Control over Mycobacterial Promoters

artículo científico publicado en 2016

On the three-finger protein domain fold and CD59-like proteins in Schistosoma mansoni.

artículo científico publicado en 2013

Optimization and scale-up production of Zika virus ΔNS1 in Escherichia coli: application of Response Surface Methodology

artículo científico publicado en 2019

Optimization of Expression and Purification of Schistosoma mansoni Antigens in Fusion with Rhizavidin

artículo científico publicado en 2021

Optimized immune response elicited by a DNA vaccine expressing pneumococcal surface protein a is characterized by a balanced immunoglobulin G1 (IgG1)/IgG2a ratio and proinflammatory cytokine production

artículo científico publicado en 2008

Optimizing expression of Streptococcus pneumoniae surface protein a, PspA: serocross-reactivity within families of antisera induced against clades 1 and 3

scientific article published on 01 October 2007

Platelet activating factor, an endogenous mediator of inflammation, induces phenotypic transformation of rat embryo cells.

artículo científico publicado en 1993

Process intensification for production of Streptococcus pneumoniae whole-cell vaccine

scientific article published on 18 February 2020

Proliferation of mouse fibroblasts induced by 1,2-dimethylhydrazine auto-oxidation: role of iron and free radicals.

artículo científico publicado en 1997

Protection induced by pneumococcal surface protein A (PspA) is enhanced by conjugation to a Streptococcus pneumoniae capsular polysaccharide

artículo científico publicado en 2008

Protective efficacy of PspA (pneumococcal surface protein A)-based DNA vaccines: contribution of both humoral and cellular immune responses.

artículo científico publicado en 2003

PsaA (pneumococcal surface adhesin A) and PspA (pneumococcal surface protein A) DNA vaccines induce humoral and cellular immune responses against Streptococcus pneumoniae

artículo científico publicado en 2001

Rational selection of broadly cross-reactive family 2 PspA molecules for inclusion in chimeric pneumococcal vaccines.

artículo científico publicado en 2017

Recognition of pneumococcal isolates by antisera raised against PspA fragments from different clades

scientific article published on 01 March 2008

Recombinant BCG Expressing LTAK63 Adjuvant induces Superior Protection against Mycobacterium tuberculosis

artículo científico publicado en 2017

Recombinant BCG expressing a PspA-PdT fusion protein protects mice against pneumococcal lethal challenge in a prime-boost strategy.

artículo científico publicado en 2017

Recombinant BCG expressing the LTAK63 adjuvant induces increased early and long-term immune responses against Mycobacteria

artículo científico publicado en 2019

Recombinant vaccines and the development of new vaccine strategies.

artículo científico publicado en 2012

Rheumatic hand's clinical, functional and imagiological correlations following metacarpophalangeal joint silicone arthroplasty.

artículo científico publicado en 2017

Role of Streptococcus pneumoniae Proteins in Evasion of Complement-Mediated Immunity.

artículo científico publicado en 2017

Saci-1, -2, and -3 and Perere, four novel retrotransposons with high transcriptional activities from the human parasite Schistosoma mansoni

artículo científico publicado en 2004

Schistosoma mansoni Annexin 2: molecular characterization and immunolocalization

artículo científico publicado en 2010

Schistosoma mansoni Venom Allergen Like Proteins Present Differential Allergic Responses in a Murine Model of Airway Inflammation ⬇️

artículo científico publicado el 7 de febrero de 2012

Schistosoma mansoni venom allergen-like protein 18 (SmVAL18) is a plasminogen-binding protein secreted during the early stages of mammalian-host infection.

artículo científico publicado en 2018

Schistosoma mansoni venom allergen-like protein 4 (SmVAL4) is a novel lipid-binding SCP/TAPS protein that lacks the prototypical CAP motifs. Corrigendum.

artículo científico publicado en 2015

Schistosoma mansoni: molecular characterization of Alkaline Phosphatase and expression patterns across life cycle stages.

artículo científico publicado en 2011

Schistosoma mansonivenom allergen-like protein 4 (SmVAL4) is a novel lipid-binding SCP/TAPS protein that lacks the prototypical CAP motifs

artículo científico publicado en 2014

Schistosome transcriptome: insights and perspectives for functional genomics.

artículo científico publicado en 2004

Schistosomiasis--a century searching for chemotherapeutic drugs.

artículo científico publicado en 2006

Screening the Schistosoma mansoni transcriptome for genes differentially expressed in the schistosomulum stage in search for vaccine candidates.

artículo científico publicado en 2010

Selection of family 1 PspA molecules capable of inducing broad-ranging cross-reactivity by complement deposition and opsonophagocytosis by murine peritoneal cells ⬇️

artículo científico publicado el 4 de enero de 2011

Sm21.6 a novel EF-hand family protein member located on the surface of Schistosoma mansoni adult worm that failed to induce protection against challenge infection but reduced liver pathology.

artículo científico publicado en 2009

Stage and tissue expression patterns of Schistosoma mansoni venom allergen-like proteins SmVAL 4, 13, 16 and 24.

artículo científico publicado en 2017

Systemic immunization with rPotD reduces Streptococcus pneumoniae nasopharyngeal colonization in mice

artículo científico publicado en 2016

The Challenges Imposed by Dengue, Zika, and Chikungunya to Brazil

article

The Schistosome Esophagus Is a 'Hotspot' for Microexon and Lysosomal Hydrolase Gene Expression: Implications for Blood Processing

artículo científico publicado en 2015

The contribution of 700,000 ORF sequence tags to the definition of the human transcriptome.

artículo científico publicado en 2001

The long search for a serotype independent pneumococcal vaccine

artículo científico publicado en 2020

The therapeutic potential of recombinant BCG expressing the antigen S1PT in the intravesical treatment of bladder cancer.

artículo científico publicado en 2009

Too intelligent for the life sciences in Brazil: how two female researchers fought back

artículo científico publicado en 2020

Vaccines of the Future: The Role of Inflammation and Adjuvanticity

artículo científico publicado en 2015

Vitamins as influenza vaccine adjuvant components

artículo científico publicado en 2016

Whole-genome analysis of Leptospira interrogans to identify potential vaccine candidates against leptospirosis.

artículo científico publicado en 2005

Lista de obras de L C Leite

A Bivalent Recombinant BCG Expressing the S1 Subunit of the Pertussis Toxin Induces a Polyfunctional CD4 T Cell Immune Response

A Combination of Recombinant Mycobacterium bovis BCG Strains Expressing Pneumococcal Proteins Induces Cellular and Humoral Immune Responses and Protects against Pneumococcal Colonization and Sepsis

A protein chimera including PspA in fusion with PotD is protective against invasive pneumococcal infection and reduces nasopharyngeal colonization in mice.

A quantitative view of the transcriptome of Schistosoma mansoni adult-worms using SAGE

Addressing racial inequalities in a pandemic: data limitations and a call for critical analyses

Adjuvant activity of Mycobacterium bovis BCG expressing CRM197 on the immune response induced by BCG expressing tetanus toxin fragment C.

Advocacy, partnership and political commitment for TB vaccine research

Analysis of serum cross-reactivity and cross-protection elicited by immunization with DNA vaccines against Streptococcus pneumoniae expressing PspA fragments from different clades.

Carbon-centered free radical formation during the metabolism of hydrazine derivatives by neutrophils

Characterization of phosphodiesterase-5 as a surface protein in the tegument of Schistosoma mansoni.

Characterization of the snake venoms from seven Brazilian species of Bothrops by FPLC anion-exchange chromatography

Combined effects of lactoferrin and lysozyme on Streptococcus pneumoniae killing

Conjugation of PspA4Pro with Capsular Streptococcus pneumoniae Polysaccharide Serotype 14 Does Not Reduce the Induction of Cross-Reactive Antibodies

Conjugation of polysaccharide 6B from Streptococcus pneumoniae with pneumococcal surface protein A: PspA conformation and its effect on the immune response

Construction of an unmarked recombinant BCG expressing a pertussis antigen by auxotrophic complementation: protection against Bordetella pertussis challenge in neonates.

Contribution of hydrazines-derived alkyl radicals to cytotoxicity and transformation induced in normal c-myc-overexpressing mouse fibroblasts ⬇️

Current status and perspectives on protein-based pneumococcal vaccines

DNA strand scission by the carbon radical derived from 2-phenyl-ethylhydrazine metabolism.

DNA vaccines expressing pneumococcal surface protein A (PspA) elicit protection levels comparable to recombinant protein

Developing Countries Vaccine Manufacturers Network (DCVMN): engaging to step up for vaccine discovery and access. Meeting report 2012.

Developing Countries Vaccine Manufacturers Network: doing good by making high-quality vaccines affordable for all.

Development of a whole cell pneumococcal vaccine: BPL inactivation, cGMP production, and stability.

Enhancement of Th1 lung immunity induced by recombinant Mycobacterium bovis Bacillus Calmette-Guerin attenuates airway allergic disease

Expression and characterization of cholera toxin B-pneumococcal surface adhesin A fusion protein in Escherichia coli: ability of CTB-PsaA to induce humoral immune response in mice

Expression of Streptococcus pneumoniae antigens, PsaA (pneumococcal surface antigen A) and PspA (pneumococcal surface protein A) by Lactobacillus casei.

First report of a dead giant squid (Architeuthis dux) from an operating seismic vessel

Fusion proteins containing family 1 and family 2 PspA fragments elicit protection against Streptococcus pneumoniae that correlates with antibody-mediated enhancement of complement deposition.

GMP-grade pneumococcal whole-cell vaccine injected subcutaneously protects mice from nasopharyngeal colonization and fatal aspiration-sepsis ⬇️

Genetic diversity of PspA types among nasopharyngeal isolates collected during an ongoing surveillance study of children in Brazil

HFE Variants and the Expression of Iron-Related Proteins in Breast Cancer-Associated Lymphocytes and Macrophages

Hemoglobin-mediated oxidation of the carcinogen 1,2-dimethylhydrazine to methyl radicals

Humoral immune response of a pneumococcal conjugate vaccine: Capsular polysaccharide serotype 14—Lysine modified PspA

IL-17A and complement contribute to killing of pneumococci following immunization with a pneumococcal whole cell vaccine.

Immunization of mice with single PspA fragments induces antibodies capable of mediating complement deposition on different pneumococcal strains and cross-protection.

Immunization with tegument nucleotidases associated with a subcurative praziquantel treatment reduces worm burden following Schistosoma mansoni challenge.

Induction of boosted immune response in mice by leptospiral surface proteins expressed in fusion with DnaK.

Induction of neutralizing antibodies against diphtheria toxin by priming with recombinant Mycobacterium bovis BCG expressing CRM(197), a mutant diphtheria toxin.

Induction of systemic and mucosal immune response and decrease in Streptococcus pneumoniae colonization by nasal inoculation of mice with recombinant lactic acid bacteria expressing pneumococcal surface antigen A.

Mycobacterial codon optimization of the gene encoding the Sm14 antigen of Schistosoma mansoni in recombinant Mycobacterium bovis Bacille Calmette-Guérin enhances protein expression but not protection against cercarial challenge in mice.

Nasal immunization of mice with Lactobacillus casei expressing the Pneumococcal Surface Protein A: induction of antibodies, complement deposition and partial protection against Streptococcus pneumoniae challenge

Neonatal immunization with a single dose of recombinant BCG expressing subunit S1 from pertussis toxin induces complete protection against Bordetella pertussis intracerebral challenge

New Recombinant Mycobacterium bovis BCG Expression Vectors: Improving Genetic Control over Mycobacterial Promoters

On the three-finger protein domain fold and CD59-like proteins in Schistosoma mansoni.

Optimization and scale-up production of Zika virus ΔNS1 in Escherichia coli: application of Response Surface Methodology

Optimization of Expression and Purification of Schistosoma mansoni Antigens in Fusion with Rhizavidin

Optimized immune response elicited by a DNA vaccine expressing pneumococcal surface protein a is characterized by a balanced immunoglobulin G1 (IgG1)/IgG2a ratio and proinflammatory cytokine production

Optimizing expression of Streptococcus pneumoniae surface protein a, PspA: serocross-reactivity within families of antisera induced against clades 1 and 3

Platelet activating factor, an endogenous mediator of inflammation, induces phenotypic transformation of rat embryo cells.

Process intensification for production of Streptococcus pneumoniae whole-cell vaccine

Proliferation of mouse fibroblasts induced by 1,2-dimethylhydrazine auto-oxidation: role of iron and free radicals.

Protection induced by pneumococcal surface protein A (PspA) is enhanced by conjugation to a Streptococcus pneumoniae capsular polysaccharide

Protective efficacy of PspA (pneumococcal surface protein A)-based DNA vaccines: contribution of both humoral and cellular immune responses.

PsaA (pneumococcal surface adhesin A) and PspA (pneumococcal surface protein A) DNA vaccines induce humoral and cellular immune responses against Streptococcus pneumoniae

Rational selection of broadly cross-reactive family 2 PspA molecules for inclusion in chimeric pneumococcal vaccines.

Recognition of pneumococcal isolates by antisera raised against PspA fragments from different clades

Recombinant BCG Expressing LTAK63 Adjuvant induces Superior Protection against Mycobacterium tuberculosis

Recombinant BCG expressing a PspA-PdT fusion protein protects mice against pneumococcal lethal challenge in a prime-boost strategy.

Recombinant BCG expressing the LTAK63 adjuvant induces increased early and long-term immune responses against Mycobacteria

Recombinant vaccines and the development of new vaccine strategies.

Rheumatic hand's clinical, functional and imagiological correlations following metacarpophalangeal joint silicone arthroplasty.

Role of Streptococcus pneumoniae Proteins in Evasion of Complement-Mediated Immunity.

Saci-1, -2, and -3 and Perere, four novel retrotransposons with high transcriptional activities from the human parasite Schistosoma mansoni

Schistosoma mansoni Annexin 2: molecular characterization and immunolocalization

Schistosoma mansoni Venom Allergen Like Proteins Present Differential Allergic Responses in a Murine Model of Airway Inflammation ⬇️

Schistosoma mansoni venom allergen-like protein 18 (SmVAL18) is a plasminogen-binding protein secreted during the early stages of mammalian-host infection.

Schistosoma mansoni venom allergen-like protein 4 (SmVAL4) is a novel lipid-binding SCP/TAPS protein that lacks the prototypical CAP motifs. Corrigendum.

Schistosoma mansoni: molecular characterization of Alkaline Phosphatase and expression patterns across life cycle stages.

Schistosoma mansonivenom allergen-like protein 4 (SmVAL4) is a novel lipid-binding SCP/TAPS protein that lacks the prototypical CAP motifs

Schistosome transcriptome: insights and perspectives for functional genomics.

Schistosomiasis--a century searching for chemotherapeutic drugs.

Screening the Schistosoma mansoni transcriptome for genes differentially expressed in the schistosomulum stage in search for vaccine candidates.

Selection of family 1 PspA molecules capable of inducing broad-ranging cross-reactivity by complement deposition and opsonophagocytosis by murine peritoneal cells ⬇️

Sm21.6 a novel EF-hand family protein member located on the surface of Schistosoma mansoni adult worm that failed to induce protection against challenge infection but reduced liver pathology.

Stage and tissue expression patterns of Schistosoma mansoni venom allergen-like proteins SmVAL 4, 13, 16 and 24.

Systemic immunization with rPotD reduces Streptococcus pneumoniae nasopharyngeal colonization in mice

The Challenges Imposed by Dengue, Zika, and Chikungunya to Brazil

The Schistosome Esophagus Is a 'Hotspot' for Microexon and Lysosomal Hydrolase Gene Expression: Implications for Blood Processing

The contribution of 700,000 ORF sequence tags to the definition of the human transcriptome.

The long search for a serotype independent pneumococcal vaccine