Lista de obras - Jennings IG - Dominio Público Uruguay

A naphthoquinone adsorbent for affinity chromatography of human dihydropteridine reductase

artículo científico publicado el 1 de febrero de 1978

Biochemical defect of the hph-1 mouse mutant is a deficiency in GTP-cyclohydrolase activity

artículo científico publicado en 1988

Biophysical characterization of interactions involving importin-alpha during nuclear import

artículo científico publicado en 2001

Class II but Not Second Class-Prospects for the Development of Class II PI3K Inhibitors.

artículo científico publicado en 2014

Comparative studies of four monoclonal antibodies to phenylalanine hydroxylase exhibiting different properties with respect to substrate-dependence, species-specificity and a range of effects on enzyme activity.

artículo científico publicado en 1981

Development of single and mixed isoform selectivity PI3Kδ inhibitors by targeting Asn836 of PI3Kδ.

artículo científico publicado en 2016

Discovery and antiplatelet activity of a selective PI3Kβ inhibitor (MIPS-9922).

artículo científico publicado en 2016

Disrupting the platelet internal membrane via PI3KC2α inhibition impairs thrombosis independently of canonical platelet activation

artículo científico publicado en 2020

Experimental determination of the phosphorylation state of phenylalanine hydroxylase

artículo científico publicado en 1990

Genetics of mammalian phenylalanine hydroxylase system. IV. Evidence of phenylalanine hydroxylase in a cultured human hepatoma cell line.

artículo científico publicado en 1980

Genetics of the mammalian phenylalanine hydroxylase system. Studies of human liver phenylalanine hydroxylase subunit structure and of mutations in phenylketonuria ⬇️

artículo científico publicado el 1 de agosto de 1979

Immobilization of tryptophan hydroxylase by immune adsorption: a method to study regulation of catalytic activity

artículo científico publicado el 1 de diciembre de 1992

Observations indicating the nature of the mutation in phenylketonuria

scientific article published on 01 January 1980

Phosphorylation and activation of tryptophan hydroxylase by exogenous protein kinase A.

artículo científico publicado en 1996

Phosphorylation regulates copper-responsive trafficking of the Menkes copper transporting P-type ATPase.

artículo científico publicado en 2009

Potent inhibitors of phosphatidylinositol 3 (PI3) kinase that have antiproliferative activity only when delivered as prodrug forms.

artículo científico publicado en 2013

Regulation of the renal-specific Na+-K+-2Cl- co-transporter NKCC2 by AMP-activated protein kinase (AMPK).

artículo científico publicado en 2007

Structural similarities among enzyme pterin binding sites as demonstrated by a monoclonal anti-idiotypic antibody

scientific article published on 01 February 1990

Structure and function of the aromatic amino acid hydroxylases.

artículo científico publicado en 1995

Structure function studies of the phenylalanine hydroxylase active site and a summary of structural features

artículo científico publicado en 1993

Structure/function analysis of the domains required for the multimerisation of phenylalanine hydroxylase

artículo científico publicado en 1998

Synthesis of linear and angular aryl-morpholino-naphth-oxazines, their DNA-PK, PI3K, PDE3A and antiplatelet activity.

artículo científico publicado en 2016

Synthesis, structure elucidation, DNA-PK and PI3K and anti-cancer activity of 8- and 6-aryl-substituted-1-3-benzoxazines.

artículo científico publicado en 2016

Thiophene inhibitors of PDE4: crystal structures show a second binding mode at the catalytic domain of PDE4D2

artículo científico publicado en 2011

Tryptophan hydroxylase is phosphorylated by protein kinase A

artículo científico publicado en 1995

Turn up the HEAT.

artículo científico publicado en 1999

Use of naphthoquinone adsorbent for the isolation of human dihydropteridine reductase

scientific article published on 01 January 1987

Vectors for expression and amplification of cDNA in mammalian cells: expression of rat phenylalanine hydroxylase

scientific article published on 01 December 1986

[Detection of phenylalanine hydroxylase protein in human platelets. Immunochemical detection]

scientific article published on 01 April 1990

[Phenylalanine hydroxylase-like antibody in human chorionic villi]

artículo científico publicado en 1992

Lista de obras de Jennings IG

A naphthoquinone adsorbent for affinity chromatography of human dihydropteridine reductase

Biochemical defect of the hph-1 mouse mutant is a deficiency in GTP-cyclohydrolase activity

Biophysical characterization of interactions involving importin-alpha during nuclear import

Class II but Not Second Class-Prospects for the Development of Class II PI3K Inhibitors.

Comparative studies of four monoclonal antibodies to phenylalanine hydroxylase exhibiting different properties with respect to substrate-dependence, species-specificity and a range of effects on enzyme activity.

Development of single and mixed isoform selectivity PI3Kδ inhibitors by targeting Asn836 of PI3Kδ.

Discovery and antiplatelet activity of a selective PI3Kβ inhibitor (MIPS-9922).

Disrupting the platelet internal membrane via PI3KC2α inhibition impairs thrombosis independently of canonical platelet activation

Experimental determination of the phosphorylation state of phenylalanine hydroxylase

Genetics of mammalian phenylalanine hydroxylase system. IV. Evidence of phenylalanine hydroxylase in a cultured human hepatoma cell line.

Genetics of the mammalian phenylalanine hydroxylase system. Studies of human liver phenylalanine hydroxylase subunit structure and of mutations in phenylketonuria ⬇️

Immobilization of tryptophan hydroxylase by immune adsorption: a method to study regulation of catalytic activity

Observations indicating the nature of the mutation in phenylketonuria

Phosphorylation and activation of tryptophan hydroxylase by exogenous protein kinase A.

Phosphorylation regulates copper-responsive trafficking of the Menkes copper transporting P-type ATPase.

Potent inhibitors of phosphatidylinositol 3 (PI3) kinase that have antiproliferative activity only when delivered as prodrug forms.

Regulation of the renal-specific Na+-K+-2Cl- co-transporter NKCC2 by AMP-activated protein kinase (AMPK).

Structural similarities among enzyme pterin binding sites as demonstrated by a monoclonal anti-idiotypic antibody

Structure and function of the aromatic amino acid hydroxylases.

Structure function studies of the phenylalanine hydroxylase active site and a summary of structural features

Structure/function analysis of the domains required for the multimerisation of phenylalanine hydroxylase

Synthesis of linear and angular aryl-morpholino-naphth-oxazines, their DNA-PK, PI3K, PDE3A and antiplatelet activity.

Synthesis, structure elucidation, DNA-PK and PI3K and anti-cancer activity of 8- and 6-aryl-substituted-1-3-benzoxazines.

Thiophene inhibitors of PDE4: crystal structures show a second binding mode at the catalytic domain of PDE4D2

Tryptophan hydroxylase is phosphorylated by protein kinase A

Turn up the HEAT.

Use of naphthoquinone adsorbent for the isolation of human dihydropteridine reductase

Vectors for expression and amplification of cDNA in mammalian cells: expression of rat phenylalanine hydroxylase

[Detection of phenylalanine hydroxylase protein in human platelets. Immunochemical detection]

[Phenylalanine hydroxylase-like antibody in human chorionic villi]