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Lista de obras de Ana Lluch

18F-fluoromisonidazole PET and Activity of Neoadjuvant Nintedanib in Early HER2-Negative Breast Cancer: A Window-of-Opportunity Randomized Trial.

artículo científico publicado en 2016

5-year analysis of neoadjuvant pertuzumab and trastuzumab in patients with locally advanced, inflammatory, or early-stage HER2-positive breast cancer (NeoSphere): a multicentre, open-label, phase 2 randomised trial.

artículo científico publicado en 2016

A PAM50-Based Chemoendocrine Score for Hormone Receptor-Positive Breast Cancer with an Intermediate Risk of Relapse.

artículo científico publicado en 2016

A customized pigmentation SNP array identifies a novel SNP associated with melanoma predisposition in the SLC45A2 gene.

artículo científico publicado en 2011

A definition for aggressive disease in patients with HER-2 negative metastatic breast cancer: an expert consensus of the Spanish Society of Medical Oncology (SEOM).

artículo científico publicado en 2016

A genomic predictor of response and survival following taxane-anthracycline chemotherapy for invasive breast cancer.

artículo científico publicado en 2011

A randomized phase II trial of platinum salts in basal-like breast cancer patients in the neoadjuvant setting. Results from the GEICAM/2006-03, multicenter study ⬇️

artículo científico publicado el 9 de octubre de 2012

Adjuvant Tamoxifen Plus Ovarian Function Suppression Versus Tamoxifen Alone in Premenopausal Women With Early Breast Cancer: Patient-Reported Outcomes in the Suppression of Ovarian Function Trial.

artículo científico publicado en 2016

An evaluation of the impact of technical bias on the concordance rate between primary and recurrent tumors in breast cancer.

artículo científico publicado en 2013

Anthracycline cardiotoxicity in the elderly cancer patient: a SIOG expert position paper.

artículo científico publicado en 2010

Aromatase activity and estradiol in human breast cancer: its relationship to estradiol and epidermal growth factor receptors and to tumor-node-metastasis staging

artículo científico publicado en 1992

Associations between aromatase CYP19 rs10046 polymorphism and breast cancer risk: from a case-control to a meta-analysis of 20,098 subjects.

artículo científico publicado en 2013

Autocrine CCL5 effect mediates trastuzumab resistance by ERK pathway activation in HER2-positive breast cancer

scientific article published on 13 May 2020

Biweekly paclitaxel plus gemcitabine in advanced breast cancer: phase II trial and predictive value of HER2 extracellular domain.

artículo científico publicado en 2004

CA 15.3, CEA and TPA tumor markers in the early diagnosis of breast cancer relapse

artículo científico publicado en 1994

CIP2A confirms its prognostic value in triple-negative breast cancer

scientific article published on 09 January 2017

Chemotherapy (CT) and hormonotherapy (HT) as neoadjuvant treatment in luminal breast cancer patients: results from the GEICAM/2006-03, a multicenter, randomized, phase-II study.

artículo científico publicado en 2012

Chromosomal abnormalities in women with breast cancer after autologous stem cell transplantation are infrequent and may not predict development of therapy-related leukemia or myelodysplastic syndrome

scientific article published on 01 June 2000

Circulating miR-99a-5p Expression in Plasma: A Potential Biomarker for Early Diagnosis of Breast Cancer

artículo científico publicado en 2020

Clinical implications of routine genomic mutation sequencing in PIK3CA/AKT1 and KRAS/NRAS/BRAF in metastatic breast cancer.

artículo científico

Concordance of genomic alterations between primary and recurrent breast cancer.

artículo científico publicado en 2014

Correction to: Persistent major alopecia following adjuvant docetaxel for breast cancer: incidence, characteristics, and prevention with scalp cooling

artículo científico publicado en 2018

Cost-utility analysis of nanoparticle albumin-bound paclitaxel versus paclitaxel in monotherapy in pretreated metastatic breast cancer in Spain.

artículo científico publicado en 2013

Critically short telomeres and toxicity of chemotherapy in early breast cancer

artículo científico publicado en 2017

Current controversies in the management of early breast cancer.

artículo científico publicado en 2007

Defective cyclin B1 induction in trastuzumab-emtansine (T-DM1) acquired resistance in HER2-positive breast cancer.

artículo científico publicado en 2017

Deficiency in p53 is required for doxorubicin induced transcriptional activation of NF-кB target genes in human breast cancer

artículo científico publicado en 2014

Deletion of chromosome 11q predicts response to anthracycline-based chemotherapy in early breast cancer

artículo científico publicado en 2007

Deletion of the PER3 gene on chromosome 1p36 in recurrent ER-positive breast cancer

artículo científico publicado en 2010

Diagnosis and medical treatment of breast cancer. Cordoba Consensus of 2007.

artículo científico publicado en 2008

Doxorubicin and paclitaxel in advanced breast carcinoma: importance of prior adjuvant anthracycline therapy.

artículo científico publicado en 2000

Efficacy and safety of neoadjuvant pertuzumab and trastuzumab in women with locally advanced, inflammatory, or early HER2-positive breast cancer (NeoSphere): a randomised multicentre, open-label, phase 2 trial

artículo científico publicado en 2012

Emerging EGFR antagonists for breast cancer.

artículo científico

Enhanced MAF Oncogene Expression and Breast Cancer Bone Metastasis

artículo científico publicado en 2015

Epidermal growth factor in human breast cancer, endometrial carcinoma and lung cancer. Its relationship to epidermal growth factor receptor, estradiol receptor and tumor TNM

scientific article published on 01 April 1993

Epirubicin Plus Cyclophosphamide Followed by Docetaxel Versus Epirubicin Plus Docetaxel Followed by Capecitabine As Adjuvant Therapy for Node-Positive Early Breast Cancer: Results From the GEICAM/2003-10 Study

scientific article published on 28 September 2015

Estradiol receptors in combination with neu or myc oncogene amplifications might define new subtypes of breast cancer

artículo científico publicado en 1994

Evaluating the Applicability of Data-Driven Dietary Patterns to Independent Samples with a Focus on Measurement Tools for Pattern Similarity

artículo científico publicado en 2016

Evaluation of a 30-gene paclitaxel, fluorouracil, doxorubicin, and cyclophosphamide chemotherapy response predictor in a multicenter randomized trial in breast cancer.

artículo científico publicado en 2010

Evaluation of international treatment guidelines and prognostic tests for the treatment of early breast cancer.

artículo científico publicado en 2008

Evidence-based use of taxanes in the adjuvant setting of breast cancer. A review of randomized phase III trials.

artículo científico publicado en 2007

Evolution of tumour biology upon progression. Do we know our enemy?

artículo científico publicado en 2012

Final 10-year results of the Breast International Group 2-98 phase III trial and the role of Ki67 in predicting benefit of adjuvant docetaxel in patients with oestrogen receptor positive breast cancer.

artículo científico publicado en 2015

Finding the right dose of fulvestrant in breast cancer ⬇️

artículo científico publicado el 15 de julio de 2012

Fluorouracil, doxorubicin, and cyclophosphamide (FAC) versus FAC followed by weekly paclitaxel as adjuvant therapy for high-risk, node-negative breast cancer: results from the GEICAM/2003-02 study

artículo científico publicado en 2013

FoxA and LIPG endothelial lipase control the uptake of extracellular lipids for breast cancer growth

artículo científico publicado en 2016

Gemcitabine and capecitabine in previously anthracycline-treated metastatic breast cancer: a multicenter phase II study (SOLTI 0301 trial).

artículo científico publicado en 2009

Gemcitabine in combination with doxorubicin in advanced breast cancer: final results of a phase II pharmacokinetic trial

artículo científico publicado en 2000

Generation, characterization, and maintenance of trastuzumab-resistant HER2+ breast cancer cell lines

artículo científico publicado en 2016

Genetic variants in PARP1 (rs3219090) and IRF4 (rs12203592) genes associated with melanoma susceptibility in a Spanish population

artículo científico publicado en 2013

Genomic profile of breast cancer: cost-effectiveness analysis from the Spanish National Healthcare System perspective.

artículo científico publicado en 2014

Germline mutations in CDKN2A are infrequent in female patients with melanoma and breast cancer.

artículo científico publicado en 2009

HDAC5 Inhibitors as a Potential Treatment in Breast Cancer Affecting Very Young Women

scientific article published on 10 February 2020

HRAS1 minisatellite alleles and breast cancer in Spanish women under age forty years. ⬇️

artículo científico publicado en 2000

Heterogeneous lack of expression of the tumour suppressor PTEN protein in human neoplastic tissues

scientific article published on 01 January 2001

High ERK protein expression levels correlate with shorter survival in triple-negative breast cancer patients

artículo científico publicado en 2012

High Numbers of Circulating CD57+ NK Cells Associate with Resistance to HER2-Specific Therapeutic Antibodies in HER2+ Primary Breast Cancer

artículo científico publicado en 2019

High Proliferation Predicts Pathological Complete Response to Neoadjuvant Chemotherapy in Early Breast Cancer

artículo científico publicado en 2016

High Proliferation Predicts Pathological Complete Response to Neoadjuvant Chemotherapy in Early Breast Cancer

artículo científico publicado en 2016

High stability of microRNAs in tissue samples of compromised quality

scientific article published on 03 October 2013

Identification of candidate polymorphisms on stress oxidative and DNA damage repair genes related with clinical outcome in breast cancer patients.

artículo científico publicado en 2012

Immune modulation of pathologic complete response after neoadjuvant HER2-directed therapies in the NeoSphere trial.

artículo científico publicado en 2015

Impact of a mammography screening programme on the breast cancer population of the Region of Valencia (Spain).

artículo científico publicado en 2008

Implementation and assessment of a fast-track programme to improve communication between primary and specialized care in patients with suspected cancer: how to shorten time between initial symptoms of cancer, diagnosis and initiation of treatment

artículo científico publicado en 2014

In response: Genomic profile of breast cancer

artículo científico publicado en 2015

Integrating radical local treatment of the primary in the management of stage IV breast cancer. When is the best moment for the resection of the primary tumor?

artículo científico publicado en 2012

Interleukin-6 concentration changes in plasma and saliva in bisphosphonate-related osteonecrosis of the jaws.

artículo científico publicado en 2013

Intratumoral variation of estrogen and progesterone receptors in breast cancer: relationship with histopathological characteristics of the tumor.

artículo científico publicado en 1990

Intratumoral variations in cytoplasmic estrogen receptor levels in breast cancer

artículo científico publicado en 1987

Intrinsic Subtypes and Gene Expression Profiles in Primary and Metastatic Breast Cancer.

artículo científico publicado en 2017

Involvement of Different networks in mammary gland involution after the pregnancy/lactation cycle: Implications in breast cancer.

artículo científico

Long telomere length and a TERT-CLPTM1 locus polymorphism association with melanoma risk.

artículo científico publicado en 2014

Low number of examined lymph nodes in node-negative breast cancer patients is an adverse prognostic factor

artículo científico publicado en 2006

Lower Breast Cancer Risk among Women following the World Cancer Research Fund and American Institute for Cancer Research Lifestyle Recommendations: EpiGEICAM Case-Control Study.

artículo científico publicado en 2015

MC1R, SLC45A2 and TYR genetic variants involved in melanoma susceptibility in southern European populations: results from a meta-analysis.

artículo científico publicado en 2012

MSK1 regulates luminal cell differentiation and metastatic dormancy in ER+ breast cancer

artículo científico publicado en 2018

MYC and MCL1 Cooperatively Promote Chemotherapy-Resistant Breast Cancer Stem Cells via Regulation of Mitochondrial Oxidative Phosphorylation

artículo científico publicado en 2017

Mechanism of suppression of the depressed lymphocyte response in lung cancer patients

artículo científico publicado en 1985

MicroRNA Profile in Response to Doxorubicin Treatment in Breast Cancer

artículo científico publicado en 2015

MicroRNA profile in very young women with breast cancer

artículo científico publicado en 2014

Mobilization of peripheral blood progenitor cells with a combination of cyclophosphamide, r-metHuSCF and filgrastim in patients with breast cancer previously treated with chemotherapy

scientific article published on 01 February 2003

Molecular biology in breast cancer: intrinsic subtypes and signaling pathways.

artículo científico

Mutational analysis of BRCA1 and BRCA2 genes in Spanish women with early-onset breast cancer

artículo científico publicado en 2000

NH(2)-terminal truncated HER-2 protein but not full-length receptor is associated with nodal metastasis in human breast cancer

scientific article published on 01 February 2002

NK Cell Infiltrates and HLA Class I Expression in Primary HER2+ Breast Cancer Predict and Uncouple Pathological Response and Disease-free Survival

artículo científico publicado en 2018

Nab-Paclitaxel in Metastatic Breast Cancer: Defining the Best Patient Profile.

artículo científico

Neoadjuvant and adjuvant trastuzumab in patients with HER2-positive locally advanced breast cancer (NOAH): follow-up of a randomised controlled superiority trial with a parallel HER2-negative cohort

artículo científico publicado en 2014

Nitration of cathepsin D enhances its proteolytic activity during mammary gland remodelling after lactation

artículo científico publicado en 2009

Non-canonical NF-κB pathway activation predicts outcome in borderline oestrogen receptor positive breast carcinoma

artículo científico publicado en 2016

Nonpegylated Liposomal Doxorubicin (TLC-D99), Paclitaxel, and Trastuzumab in HER-2-Overexpressing Breast Cancer: A Multicenter Phase I/II Study

artículo científico publicado en 2009

Nuclear PARP-1 protein overexpression is associated with poor overall survival in early breast cancer ⬇️

artículo científico publicado el 9 de septiembre de 2011

Obesity and survival in operable breast cancer patients treated with adjuvant anthracyclines and taxanes according to pathological subtypes: a pooled analysis

artículo científico publicado en 2013

Outcome differences between patients with node-negative breast cancer classified according to the st. Gallen risk categories.

artículo científico publicado en 2009

PI3K pathway mutations and PTEN levels in primary and metastatic breast cancer.

artículo científico publicado en 2011

PP2A inhibition determines poor outcome and doxorubicin resistance in early breast cancer and its activation shows promising therapeutic effects

artículo científico publicado en 2015

Paclitaxel plus doxorubicin in metastatic breast cancer: preliminary analysis of cardiotoxicity

artículo científico publicado el 1 de octubre de 1997

Paclitaxel plus vinorelbine: an active regimen in metastatic breast cancer patients with prior anthracycline exposure.

artículo científico publicado en 2000

Parotid gland metastasis of a breast cancer

scientific article published on 01 April 2007

Pathological complete response rates following different neoadjuvant chemotherapy regimens for operable breast cancer according to ER status, in two parallel, randomized phase II trials with an adaptive study design (ECTO II)

article

Patterns of HER2 Gene Amplification and Response to Anti-HER2 Therapies

artículo científico publicado en 2015

Persistent major alopecia following adjuvant docetaxel for breast cancer: incidence, characteristics, and prevention with scalp cooling

artículo científico publicado en 2018

Pertuzumab monotherapy after trastuzumab-based treatment and subsequent reintroduction of trastuzumab: activity and tolerability in patients with advanced human epidermal growth factor receptor 2-positive breast cancer.

artículo científico publicado en 2012

Phase I study of oral vinorelbine and capecitabine in patients with metastatic breast cancer.

artículo científico publicado en 2010

Phase II Clinical Trial of Ixabepilone (BMS-247550), an Epothilone B Analog, in Patients With Taxane-Resistant Metastatic Breast Cancer

artículo científico publicado en 2007

Phase II and tumor pharmacodynamic study of gefitinib in patients with advanced breast cancer.

artículo científico publicado en 2005

Phase II study of pemetrexed in breast cancer patients pretreated with anthracyclines.

artículo científico publicado en 2003

Phase II trial of cisplatin and etoposide as first-line therapy in metastatic breast carcinoma

artículo científico publicado en 1994

Phase II trial of weekly IV vinorelbine in first-line advanced breast cancer chemotherapy

artículo científico publicado en 1994

Phase III trial evaluating the addition of paclitaxel to doxorubicin followed by cyclophosphamide, methotrexate, and fluorouracil, as adjuvant or primary systemic therapy: European Cooperative Trial in Operable Breast Cancer.

artículo científico publicado en 2009

Poly (ADP-ribose) polymerase inhibition enhances trastuzumab antitumour activity in HER2 overexpressing breast cancer.

artículo científico publicado en 2014

Pooled analysis of prospective European studies assessing the impact of using the 21-gene Recurrence Score assay on clinical decision making in women with oestrogen receptor-positive, human epidermal growth factor receptor 2-negative early-stage bre

artículo científico publicado en 2016

Predicting response and survival in chemotherapy-treated triple-negative breast cancer.

artículo científico publicado en 2014

Prognostic Impact of Phosphorylated HER-2 in HER-2+ Primary Breast Cancer ⬇️

artículo científico publicado el 28 de junio de 2011

Prognostic factors in patients with isolated recurrences of breast cancer (stage IV-NED)

artículo científico publicado en 1999

Prognostic factors predicting survival from first recurrence in patients with metastatic breast cancer: analysis of 439 patients

scientific article published on 01 July 1999

Prognostic significance of c-erbB-2/neu amplification and epidermal growth factor receptor (EGFR) in primary breast cancer and their relation to estradiol receptor (ER) status

artículo científico publicado en 1997

Prognostic significance of the immunocytochemical detection of contaminating tumor cells (CTC) in apheresis products of patients with high-risk breast cancer treated with high-dose chemotherapy and stem cell transplantation

scientific article published on 01 February 2001

Progress against solid tumors in danger: the metastatic breast cancer example

artículo científico publicado en 2012

Prospective transGEICAM study of the impact of the 21-gene Recurrence Score assay and traditional clinicopathological factors on adjuvant clinical decision making in women with estrogen receptor-positive (ER+) node-negative breast cancer.

artículo científico publicado en 2011

Quality Indicators to Assure and Improve Cancer Care in Spain Using the Delphi Technique

artículo científico publicado en 2016

Quantitative monoclonal antibody determination of estrogen and progesterone receptors in human breast cancer: correlation with the radioligand method

scientific article published on 01 September 1994

Randomized phase III trial of pegylated liposomal doxorubicin versus vinorelbine or mitomycin C plus vinblastine in women with taxane-refractory advanced breast cancer.

artículo científico publicado en 2004

Randomized, double-blind, multicenter trial comparing two doses of arzoxifene (LY353381) in hormone-sensitive advanced or metastatic breast cancer patients.

artículo científico publicado en 2003

Randomized, placebo-controlled, double-blind, phase II study of axitinib plus docetaxel versus docetaxel plus placebo in patients with metastatic breast cancer.

artículo científico publicado en 2011

Recent Insights into the Development of Preclinical Trastuzumab-Resistant HER2+ Breast Cancer Models

artículo científico publicado en 2016

Recommendations for the prevention, diagnosis, and treatment of osteonecrosis of the jaw (ONJ) in cancer patients treated with bisphosphonates.

artículo científico publicado en 2007

Removal of primary tumor improves survival in metastatic breast cancer. Does timing of surgery influence outcomes?

artículo científico publicado en 2011

Retrospective analysis of the use of G-CSF and its impact on dose response for anthracycline plus taxane-based schedules in early breast cancer

artículo científico publicado en 2014

Role of MTHFR (677, 1298) haplotype in the risk of developing secondary leukemia after treatment of breast cancer and hematological malignancies

artículo científico publicado en 2007

Role of glutathione S-transferases in melanoma susceptibility: association with GSTP1 rs1695 polymorphism.

artículo científico publicado en 2012

SOLTI (Solid Tumor Intensification) Group experience with high-dose chemotherapy treatment for early breast carcinoma

Snail1-expressing fibroblasts in the tumor microenvironment display mechanical properties that support metastasis

artículo científico publicado en 2014

Spanish Mediterranean diet and other dietary patterns and breast cancer risk: case-control EpiGEICAM study

artículo científico publicado en 2014

Standard versus continuous administration of capecitabine in metastatic breast cancer (GEICAM/2009-05): a randomized, noninferiority phase II trial with a pharmacogenetic analysis

artículo científico publicado en 2015

Sunitinib in combination with trastuzumab for the treatment of advanced breast cancer: activity and safety results from a phase II study

artículo científico publicado en 2014

Supportive care for patients with early breast cancer.

scientific article published on January 2010

Surgery following neoadjuvant therapy in patients with HER2-positive locally advanced or inflammatory breast cancer participating in the NeOAdjuvant Herceptin (NOAH) study.

artículo científico publicado en 2011

The "El Alamo" project (1990-1997): two consecutive hospital-based studies of breast cancer outcomes in Spain

scientific article published on 01 July 2006

The Antitumor Effect of Metformin Is Mediated by miR-26a in Breast Cancer

artículo científico publicado en 2016

The effect of body mass index on overall and disease-free survival in node-positive breast cancer patients treated with docetaxel and doxorubicin-containing adjuvant chemotherapy: the experience of the BIG 02-98 trial

artículo científico publicado en 2010

The miRNA-449 family mediates doxorubicin resistance in triple-negative breast cancer by regulating cell cycle factors

artículo científico publicado en 2019

The role of miR-26a and miR-30b in HER2+ breast cancer trastuzumab resistance and regulation of the CCNE2 gene

artículo científico publicado en 2017

The single-nucleotide polymorphisms +936 C/T VEGF and -710 C/T VEGFR1 are associated with breast cancer protection in a Spanish population.

artículo científico publicado en 2012

The use of taxanes in the neoadjuvant treatment of breast cancer: a review of randomized phase II/III trials.

artículo científico publicado en 2007

Time-to-progression in breast cancer: a stratification model for clinical trials.

artículo científico publicado en 2007

Trastuzumab in small tumours and in elderly women.

artículo científico

Trastuzumab or lapatinib with standard chemotherapy for HER2-positive breast cancer: results from the GEICAM/2006-14 trial.

scientific article published on 23 January 2014

Treatment innovations for metastatic breast cancer: nanoparticle albumin-bound (NAB) technology targeted to tumors.

artículo científico

Treatment of HER2 positive advanced breast cancer with T-DM1: A review of the literature.

artículo científico

Treatment with a nonanthracycline regimen in advanced breast cancer: vinorelbine, cyclophosphamide, and 5-fluorouracil with folinic acid

artículo científico publicado en 1999

Triple-negative breast cancer: molecular features, pathogenesis, treatment and current lines of research.

artículo científico publicado en 2010

Tumor-Associated Fibroblasts Promote HER2-Targeted Therapy Resistance through FGFR2 Activation

scientific article published on 07 November 2019

Twelve-Month Estrogen Levels in Premenopausal Women With Hormone Receptor-Positive Breast Cancer Receiving Adjuvant Triptorelin Plus Exemestane or Tamoxifen in the Suppression of Ovarian Function Trial (SOFT): The SOFT-EST Substudy

artículo científico publicado en 2016

Value of CA 15.3 in breast cancer and comparison with CEA and TPA: a study of specificity in disease-free follow-up patients and sensitivity in patients at diagnosis of the first metastasis

artículo científico publicado en 1996

Zoledronic acid in the treatment of metastatic breast cancer

artículo científico

[Conventional and aggressive chemo-radiotherapy of chronic granulocytic leukemia in its different phases. Other therapeutic problems]

artículo científico publicado en 1984

[Epidemiological study of the GEICAM group about breast cancer in Spain (1990-1993): El Alamo project]

scientific article published on 01 January 2004

[Estrogen and progesterone receptors in cancer of the breast]

artículo científico publicado en 1987

[High-dosage chemotherapy and autologous transplant of hematopoietic germ cells from peripheral blood in high-risk recurrence carcinoma of the breast (with >= or 10 involved axillary nodes at diagnosis) Preliminary results of the Solti 9301 cooperat

scientific article published on 01 April 1997

[Multicentric prospective, randomized study of the role of filgrastim (G-CSF) after transplant of hematopoietic progenitor cells mobilized with G-CSF in patients with cancer of the breast]

artículo científico publicado en 1997

[Neoadjuvant therapy for operable breast-cancer]

scientific article published on 01 March 2006

[Toxicity and hematopoietic regeneration produced by adjuvant chemotherapy in patients with neoplasia of the breast]

scientific article published on 01 June 1988

[Treatment of locally advanced cancer of the breast]

artículo científico publicado en 1987

c-Jun N-Terminal Kinase Inactivation by Mitogen-Activated Protein Kinase Phosphatase 1 Determines Resistance to Taxanes and Anthracyclines in Breast Cancer.

artículo científico publicado en 2016

rs12512631 on the group specific complement (vitamin D-binding protein GC) implicated in melanoma susceptibility.

artículo científico publicado en 2013

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