Lista de obras - C R Garcia - Dominio Público Uruguay

A nuclear protein, PfMORC confers melatonin dependent synchrony of the human malaria parasite P. falciparum in the asexual stage.

artículo científico publicado en 2021

Acidic calcium pools in intraerythrocytic malaria parasites.

artículo científico publicado en 1998

Addition of thiols to o-quinone methide: new 2-hydroxy-3-phenylsulfanylmethyl[1,4]naphthoquinones and their activity against the human malaria parasite Plasmodium falciparum (3D7).

artículo científico publicado en 2012

An external sensing system in Plasmodium falciparum-infected erythrocytes

artículo científico publicado en 2016

Antimalarial Activity of Piperidine Alkaloids fromSenna spectabilisand Semisynthetic Derivatives

Antimalarials and the fight against malaria in Brazil

artículo científico publicado en 2009

Biliverdin targets enolase and eukaryotic initiation factor 2 (eIF2α) to reduce the growth of intraerythrocytic development of the malaria parasite Plasmodium falciparum

artículo científico publicado en 2016

Biological evaluation of hydroxynaphthoquinones as anti-malarials

artículo científico publicado en 2013

Blocking IP signal transduction pathways inhibits melatonin-induced Ca signals and impairs P. falciparum development and proliferation in erythrocytes

article

Calcium Signaling throughout the Toxoplasma gondii Lytic Cycle: A STUDY USING GENETICALLY ENCODED CALCIUM INDICATORS.

artículo científico publicado en 2015

Calcium homeostasis and signaling in the blood-stage malaria parasite.

artículo científico publicado en 1999

Calcium signaling in a low calcium environment: how the intracellular malaria parasite solves the problem.

artículo científico publicado en 2003

Combination of Bioactive Polymeric Membranes and Stem Cells for Periodontal Regeneration: In Vitro and In Vivo Analyses.

artículo científico publicado en 2016

Cyclic AMP and calcium interplay as second messengers in melatonin-dependent regulation of Plasmodium falciparum cell cycle.

artículo científico publicado en 2005

Cysteine-protease activity elicited by Ca2+ stimulus in Plasmodium.

artículo científico publicado en 2005

Dissociation of F-actin induced by hydrostatic pressure

artículo científico publicado en 1992

Encapsulation of metalloporphyrins improves their capacity to block the viability of the human malaria parasite Plasmodium falciparum.

artículo científico publicado en 2014

Evidence for Regulation of Hemoglobin Metabolism and Intracellular Ionic Flux by the Plasmodium falciparum Chloroquine Resistance Transporter

artículo científico publicado en 2018

Exposure of Plasmodium sporozoites to the intracellular concentration of potassium enhances infectivity and reduces cell passage activity.

artículo científico publicado en 2007

Extracellular ATP triggers proteolysis and cytosolic Ca²⁺ rise in Plasmodium berghei and Plasmodium yoelii malaria parasites.

artículo científico publicado en 2012

FRET peptides reveal differential proteolytic activation in intraerythrocytic stages of the malaria parasites Plasmodium berghei and Plasmodium yoelii

artículo científico publicado en 2010

Flow cytometry as a tool for analyzing changes in Plasmodium falciparum cell cycle following treatment with indol compounds.

artículo científico publicado en 2011

Generation of second messengers in Plasmodium.

artículo científico

Genome-wide detection of serpentine receptor-like proteins in malaria parasites

artículo científico publicado en 2008

Ghost protein damage by peroxynitrite and its protection by melatonin

scientific article published on 01 January 2000

Growing Latin American science

scientific article published on 01 November 2012

Human malaria parasites display a receptor for activated C kinase ortholog

artículo científico publicado en 2003

Hybrid scaffolds built from PET and collagen as a model for vascular graft architecture.

artículo científico publicado en 2012

Identification of Plasmodium berghei Oocyst Rupture Protein 2 (ORP2) domains involved in sporozoite egress from the oocyst

artículo científico publicado en 2018

Imaging Plasmodium falciparum-infected ghost and parasite by atomic force microscopy

artículo científico publicado en 1997

In vivo uptake of a haem analogue Zn protoporphyrin IX by the human malaria parasite P. falciparum-infected red blood cells

artículo científico publicado en 2010

Inhibition of invasion and intraerythrocytic development of Plasmodium falciparum by kinase inhibitors.

artículo científico publicado en 1996

Inositol 1,4,5-trisphosphate induced Ca2+ release from chloroquine-sensitive and -insensitive intracellular stores in the intraerythrocytic stage of the malaria parasite P. chabaudi.

artículo científico publicado en 1998

InsP3 Signaling in Apicomplexan Parasites

artículo científico publicado en 2017

Insights into cytochrome bc1 complex binding mode of antimalarial 2-hydroxy-1,4-naphthoquinones through molecular modelling.

artículo científico publicado en 2017

Interruption of the blood-stage cycle of the malaria parasite, Plasmodium chabaudi, by protein tyrosine kinase inhibitors ⬇️

artículo científico publicado el 22 de octubre de 2003

Investigation of antimalarial activity, cytotoxicity and action mechanism of piperazine derivatives of betulinic acid

artículo científico publicado en 2014

Involvement of TSSA (trypomastigote small surface antigen) in Trypanosoma cruzi invasion of mammalian cells.

artículo científico publicado en 2012

Melatonin action in Plasmodium infection: Searching for molecules that modulate the asexual cycle as a strategy to impair the parasite cycle

scientific article published on 06 October 2020

Melatonin activate FIS1, DYN1 and DYN2 Plasmodium falciparum related-genes for mitochondria fission: mitoemerald-GFP as a tool to visualize mitochondria structure.

artículo científico publicado en 2018

Melatonin and IP3-induced Ca2+ release from intracellular stores in the malaria parasite Plasmodium falciparum within infected red blood cells

artículo científico publicado en 2010

Melatonin and N-acetyl-serotonin cross the red blood cell membrane and evoke calcium mobilization in malarial parasites ⬇️

artículo científico publicado el 22 de octubre de 2003

Melatonin signaling and its modulation of PfNF-YB transcription factor expression in Plasmodium falciparum.

artículo científico publicado en 2013

Melatonin-induced temporal up-regulation of gene expression related to ubiquitin/proteasome system (UPS) in the human malaria parasite Plasmodium falciparum

artículo científico publicado en 2014

Molecular and cellular approaches to understanding pathogen-host interactions in neglected diseases

artículo científico publicado en 2009

N1-acetyl-N2-formyl-5-methoxykynuramine modulates the cell cycle of malaria parasites.

artículo científico publicado en 2007

New Molecular Targets and Strategies for Antimalarial Discovery

artículo científico publicado en 2017

P2Y(1) receptor activation enhances the rate of rat pinealocyte-induced extracellular acidification via a calcium-dependent mechanism.

artículo científico publicado en 2003

Plasmodium falciparum GPCR-like receptor SR25 mediates extracellular K+ sensing coupled to Ca2+ signaling and stress survival

artículo científico publicado en 2017

Plasmodium falciparum Knockout for the GPCR-Like PfSR25 Receptor Displays Greater Susceptibility to 1,2,3-Triazole Compounds That Block Malaria Parasite Development

artículo científico publicado en 2020

Plasmodium falciparum malaria parasites display a THG-sensitive Ca2+ pool.

artículo científico publicado en 2003

Plasmodium in the postgenomic era: new insights into the molecular cell biology of malaria parasites.

artículo científico publicado en 2008

Porphyrin Derivative Nanoformulations for Therapy and Antiparasitic Agents

scientific article published on 29 April 2020

Products of tryptophan catabolism induce Ca2+ release and modulate the cell cycle of Plasmodium falciparum malaria parasites.

artículo científico publicado en 2005

Purinergic signalling is involved in the malaria parasite Plasmodium falciparum invasion to red blood cells ⬇️

artículo científico publicado el 17 de octubre de 2010

Regulation of multidrug resistance-associated protein 2 by calcium signaling in mouse liver.

artículo científico publicado en 2010

Release of Plasmodium sporozoites requires proteins with histone-fold dimerization domains

artículo científico publicado en 2016

Ribifolin, an Orbitide from Jatropha ribifolia, and Its Potential Antimalarial Activity

Role of Melatonin in the Synchronization of Asexual Forms in the Parasite Plasmodium falciparum

scientific article published on 27 August 2020

Signal transduction in Plasmodium-Red Blood Cells interactions and in cytoadherence.

artículo científico

Strategies for development of antimalarials based on encapsulated porphyrin derivatives

artículo científico publicado en 2015

Synthesis and antiplasmodial activity of betulinic acid and ursolic acid analogues.

artículo científico publicado en 2012

Synthetic indole and melatonin derivatives exhibit antimalarial activity on the cell cycle of the human malaria parasite Plasmodium falciparum.

artículo científico publicado en 2014

Targeting Plasmodium falciparum protein kinases with adenosine analogue-oligoarginine conjugates

artículo científico publicado en 2014

The GCaMP3 - A GFP-based calcium sensor for imaging calcium dynamics in the human malaria parasite Plasmodium falciparum

artículo científico publicado en 2014

The Knockout for G Protein-Coupled Receptor-Like PfSR25 Increases the Susceptibility of Malaria Parasites to the Antimalarials Lumefantrine and Piperaquine but Not to Medicine for Malaria Venture Compounds.

artículo científico publicado en 2021

The Plasmodium falciparum eIK1 kinase (PfeIK1) is central for melatonin synchronization in the human malaria parasite. Melatotosil blocks melatonin action on parasite cell cycle

scientific article published on 23 July 2020

The genetic Ca2+ sensor GCaMP3 reveals multiple Ca2+ stores differentially coupled to Ca2+ entry in the human malaria parasite Plasmodium falciparum

artículo científico publicado en 2020

The malaria parasite mitochondrion senses cytosolic Ca2+ fluctuations.

artículo científico publicado en 2004

The role of melatonin in parasite biology.

artículo científico publicado en 2011

The structurally related auxin and melatonin tryptophan-derivatives and their roles in Arabidopsis thaliana and in the human malaria parasite Plasmodium falciparum.

artículo científico publicado en 2013

Tumor necrosis factor reduces Plasmodium falciparum growth and activates calcium signaling in human malaria parasites.

artículo científico publicado en 2016

Two series of new semisynthetic triterpene derivatives: differences in anti-malarial activity, cytotoxicity and mechanism of action.

artículo científico publicado en 2013

Ubiquitin Proteasome System as a Potential Drug Target for Malaria.

artículo científico publicado en 2018

Lista de obras de C R Garcia

A nuclear protein, PfMORC confers melatonin dependent synchrony of the human malaria parasite P. falciparum in the asexual stage.

Acidic calcium pools in intraerythrocytic malaria parasites.

Addition of thiols to o-quinone methide: new 2-hydroxy-3-phenylsulfanylmethyl[1,4]naphthoquinones and their activity against the human malaria parasite Plasmodium falciparum (3D7).

An external sensing system in Plasmodium falciparum-infected erythrocytes

Antimalarial Activity of Piperidine Alkaloids fromSenna spectabilisand Semisynthetic Derivatives

Antimalarials and the fight against malaria in Brazil

Biliverdin targets enolase and eukaryotic initiation factor 2 (eIF2α) to reduce the growth of intraerythrocytic development of the malaria parasite Plasmodium falciparum

Biological evaluation of hydroxynaphthoquinones as anti-malarials

Blocking IP signal transduction pathways inhibits melatonin-induced Ca signals and impairs P. falciparum development and proliferation in erythrocytes

Calcium Signaling throughout the Toxoplasma gondii Lytic Cycle: A STUDY USING GENETICALLY ENCODED CALCIUM INDICATORS.

Calcium homeostasis and signaling in the blood-stage malaria parasite.

Calcium signaling in a low calcium environment: how the intracellular malaria parasite solves the problem.

Combination of Bioactive Polymeric Membranes and Stem Cells for Periodontal Regeneration: In Vitro and In Vivo Analyses.

Cyclic AMP and calcium interplay as second messengers in melatonin-dependent regulation of Plasmodium falciparum cell cycle.

Cysteine-protease activity elicited by Ca2+ stimulus in Plasmodium.

Dissociation of F-actin induced by hydrostatic pressure

Encapsulation of metalloporphyrins improves their capacity to block the viability of the human malaria parasite Plasmodium falciparum.

Evidence for Regulation of Hemoglobin Metabolism and Intracellular Ionic Flux by the Plasmodium falciparum Chloroquine Resistance Transporter

Exposure of Plasmodium sporozoites to the intracellular concentration of potassium enhances infectivity and reduces cell passage activity.

Extracellular ATP triggers proteolysis and cytosolic Ca²⁺ rise in Plasmodium berghei and Plasmodium yoelii malaria parasites.

FRET peptides reveal differential proteolytic activation in intraerythrocytic stages of the malaria parasites Plasmodium berghei and Plasmodium yoelii

Flow cytometry as a tool for analyzing changes in Plasmodium falciparum cell cycle following treatment with indol compounds.

Generation of second messengers in Plasmodium.

Genome-wide detection of serpentine receptor-like proteins in malaria parasites

Ghost protein damage by peroxynitrite and its protection by melatonin

Growing Latin American science

Human malaria parasites display a receptor for activated C kinase ortholog

Hybrid scaffolds built from PET and collagen as a model for vascular graft architecture.

Identification of Plasmodium berghei Oocyst Rupture Protein 2 (ORP2) domains involved in sporozoite egress from the oocyst

Imaging Plasmodium falciparum-infected ghost and parasite by atomic force microscopy

In vivo uptake of a haem analogue Zn protoporphyrin IX by the human malaria parasite P. falciparum-infected red blood cells

Inhibition of invasion and intraerythrocytic development of Plasmodium falciparum by kinase inhibitors.

Inositol 1,4,5-trisphosphate induced Ca2+ release from chloroquine-sensitive and -insensitive intracellular stores in the intraerythrocytic stage of the malaria parasite P. chabaudi.

InsP3 Signaling in Apicomplexan Parasites

Insights into cytochrome bc1 complex binding mode of antimalarial 2-hydroxy-1,4-naphthoquinones through molecular modelling.

Interruption of the blood-stage cycle of the malaria parasite, Plasmodium chabaudi, by protein tyrosine kinase inhibitors ⬇️

Investigation of antimalarial activity, cytotoxicity and action mechanism of piperazine derivatives of betulinic acid

Involvement of TSSA (trypomastigote small surface antigen) in Trypanosoma cruzi invasion of mammalian cells.

Melatonin action in Plasmodium infection: Searching for molecules that modulate the asexual cycle as a strategy to impair the parasite cycle

Melatonin activate FIS1, DYN1 and DYN2 Plasmodium falciparum related-genes for mitochondria fission: mitoemerald-GFP as a tool to visualize mitochondria structure.

Melatonin and IP3-induced Ca2+ release from intracellular stores in the malaria parasite Plasmodium falciparum within infected red blood cells

Melatonin and N-acetyl-serotonin cross the red blood cell membrane and evoke calcium mobilization in malarial parasites ⬇️

Melatonin signaling and its modulation of PfNF-YB transcription factor expression in Plasmodium falciparum.

Melatonin-induced temporal up-regulation of gene expression related to ubiquitin/proteasome system (UPS) in the human malaria parasite Plasmodium falciparum

Molecular and cellular approaches to understanding pathogen-host interactions in neglected diseases

N1-acetyl-N2-formyl-5-methoxykynuramine modulates the cell cycle of malaria parasites.

New Molecular Targets and Strategies for Antimalarial Discovery

P2Y(1) receptor activation enhances the rate of rat pinealocyte-induced extracellular acidification via a calcium-dependent mechanism.

Plasmodium falciparum GPCR-like receptor SR25 mediates extracellular K+ sensing coupled to Ca2+ signaling and stress survival

Plasmodium falciparum Knockout for the GPCR-Like PfSR25 Receptor Displays Greater Susceptibility to 1,2,3-Triazole Compounds That Block Malaria Parasite Development

Plasmodium falciparum malaria parasites display a THG-sensitive Ca2+ pool.

Plasmodium in the postgenomic era: new insights into the molecular cell biology of malaria parasites.

Porphyrin Derivative Nanoformulations for Therapy and Antiparasitic Agents

Products of tryptophan catabolism induce Ca2+ release and modulate the cell cycle of Plasmodium falciparum malaria parasites.

Purinergic signalling is involved in the malaria parasite Plasmodium falciparum invasion to red blood cells ⬇️

Regulation of multidrug resistance-associated protein 2 by calcium signaling in mouse liver.

Release of Plasmodium sporozoites requires proteins with histone-fold dimerization domains

Ribifolin, an Orbitide from Jatropha ribifolia, and Its Potential Antimalarial Activity

Role of Melatonin in the Synchronization of Asexual Forms in the Parasite Plasmodium falciparum

Signal transduction in Plasmodium-Red Blood Cells interactions and in cytoadherence.

Strategies for development of antimalarials based on encapsulated porphyrin derivatives

Synthesis and antiplasmodial activity of betulinic acid and ursolic acid analogues.

Synthetic indole and melatonin derivatives exhibit antimalarial activity on the cell cycle of the human malaria parasite Plasmodium falciparum.

Targeting Plasmodium falciparum protein kinases with adenosine analogue-oligoarginine conjugates

The GCaMP3 - A GFP-based calcium sensor for imaging calcium dynamics in the human malaria parasite Plasmodium falciparum

The Knockout for G Protein-Coupled Receptor-Like PfSR25 Increases the Susceptibility of Malaria Parasites to the Antimalarials Lumefantrine and Piperaquine but Not to Medicine for Malaria Venture Compounds.

The Plasmodium falciparum eIK1 kinase (PfeIK1) is central for melatonin synchronization in the human malaria parasite. Melatotosil blocks melatonin action on parasite cell cycle

The genetic Ca2+ sensor GCaMP3 reveals multiple Ca2+ stores differentially coupled to Ca2+ entry in the human malaria parasite Plasmodium falciparum

The malaria parasite mitochondrion senses cytosolic Ca2+ fluctuations.

The role of melatonin in parasite biology.

The structurally related auxin and melatonin tryptophan-derivatives and their roles in Arabidopsis thaliana and in the human malaria parasite Plasmodium falciparum.

Tumor necrosis factor reduces Plasmodium falciparum growth and activates calcium signaling in human malaria parasites.

Two series of new semisynthetic triterpene derivatives: differences in anti-malarial activity, cytotoxicity and mechanism of action.

Ubiquitin Proteasome System as a Potential Drug Target for Malaria.