Lista de obras - Gomis-Rüth FX - Dominio Público Uruguay

1.8‐Å Crystal Structure of the Catalytic Domain of Human Neutrophil Collagenase (Matrix Metalloproteinase‐8) Complexed with a Peptidomimetic Hydroxamate Primed‐Side Inhibitor with a Distinct Selectivity Profile ⬇️

artículo científico publicado el 1 de julio de 1997

2 angstrom X-ray structure of adamalysin II complexed with a peptide phosphonate inhibitor adopting a retro-binding mode

artículo científico publicado en 1997

A Novel Family of Soluble Minimal Scaffolds Provides Structural Insight into the Catalytic Domains of Integral Membrane Metallopeptidases

artículo científico publicado en 2013

A different look for AB5 toxins.

artículo científico publicado en 2013

A novel mechanism of latency in matrix metalloproteinases

artículo científico publicado en 2015

A novel strategy for inhibition of α-amylases: yellow meal worm α-amylase in complex with the Ragi bifunctional inhibitor at 2.5 å resolution ⬇️

artículo científico publicado el 15 de julio de 1998

A standard orientation for metallopeptidases ⬇️

artículo científico publicado el 30 de abril de 2011

A structure-derived snap-trap mechanism of a multispecific serpin from the dysbiotic human oral microbiome

artículo científico publicado en 2017

Activity of ulilysin, an archaeal PAPP-A-related gelatinase and IGFBP protease.

artículo científico publicado en 2007

Architecture and function of metallopeptidase catalytic domains

artículo científico

Astacins, serralysins, snake venom and matrix metalloproteinases exhibit identical zinc-binding environments (HEXXHXXGXXH and Met-turn) and topologies and should be grouped into a common family, the 'metzincins'

artículo científico publicado en 1993

Catalytic domain architecture of metzincin metalloproteases.

artículo científico publicado en 2009

Caught after the Act: a human A-type metallocarboxypeptidase in a product complex with a cleaved hexapeptide

artículo científico publicado en 2007

Crystal structure analysis, refinement and enzymatic reaction mechanism of N-carbamoylsarcosine amidohydrolase from Arthrobacter sp. at 2.0 A resolution

artículo científico publicado el 20 de agosto de 1992

Crystal structure of an oligomer of proteolytic zymogens: detailed conformational analysis of the bovine ternary complex and implications for their activation 1 1Edited by I. A. Wilson

article

Crystal structure of yellow meal worm α-amylase at 1.64 Å resolution ⬇️

artículo científico publicado el 8 de mayo de 1998

Crystal structures, spectroscopic features, and catalytic properties of cobalt(II), copper(II), nickel(II), and mercury(II) derivatives of the zinc endopeptidase astacin. A correlation of structure and proteolytic activity

artículo científico publicado en 1994

Crystallization and preliminary X-ray analysis of the ternary complex of procarboxypeptidase A from bovine pancreas

artículo científico publicado en 1995

Crystallization and preliminary X-ray diffraction analysis of eukaryotic α2 -macroglobulin family members modified by methylamine, proteases and glycosidases

artículo científico publicado en 2014

Crystallization and preliminary X-ray diffraction analysis of proline iminopeptidase from Xanthomonas campestris pv. citri

artículo científico publicado en 1997

Cut and move: protein machinery for DNA processing in bacterial conjugation.

artículo científico publicado en 2006

Cutting at the right place. The importance of selective limited proteolysis in the activation of proproteinase E

article

De novo design of immunoglobulin-like domains

artículo científico publicado en 2022

Detailed architecture of a DNA translocating machine: the high-resolution structure of the bacteriophage phi29 connector particle

artículo científico publicado en 2002

Determination of hemihedral twinning and initial structural analysis of crystals of the procarboxypeptidase A ternary complex

artículo científico publicado en 1995

Enzymatic and Structural Characterization of the Major Endopeptidase in the Venus Flytrap Digestion Fluid.

artículo científico publicado en 2015

Escherichia coli dihydrodipicolinate synthase. Identification of the active site and crystallization ⬇️

artículo científico publicado el 1 de diciembre de 1992

Expression and purification of integral membrane metallopeptidase HtpX.

artículo científico publicado en 2014

First structure of a snake venom metalloproteinase: a prototype for matrix metalloproteinases/collagenases

artículo científico publicado en 1993

Human procarboxypeptidase B: three-dimensional structure and implications for thrombin-activatable fibrinolysis inhibitor (TAFI)

artículo científico publicado en 2002

Inhibition of carboxypeptidase A by excess zinc: analysis of the structural determinants by X-ray crystallography

article

Insights into MMP-TIMP interactions.

artículo científico publicado en 1999

Insights into the molecular inactivation mechanism of human activated thrombin-activatable fibrinolysis inhibitor

artículo científico publicado en 2010

Mammalian metallopeptidase inhibition at the defense barrier of Ascaris parasite

artículo científico publicado en 2009

Matrix metalloproteinases outside vertebrates

artículo científico publicado en 2017

Matrix metalloproteinases: fold and function of their catalytic domains

artículo científico publicado en 2010

Mechanism of inhibition of the human matrix metalloproteinase stromelysin-1 by TIMP-1 ⬇️

artículo científico publicado el 4 de septiembre de 1997

Multiple Architectures and Mechanisms of Latency in Metallopeptidase Zymogens

artículo científico publicado en 2018

Multiple stable conformations account for reversible concentration-dependent oligomerization and autoinhibition of a metamorphic metallopeptidase

artículo científico publicado en 2014

On the Relevance of the Met-turn Methionine in Metzincins

artículo científico publicado en 2010

Overexpression, purification, crystallization and preliminary X-ray diffraction analysis of the pMV158-encoded plasmid transcriptional repressor protein CopG

artículo científico publicado en 1998

Overexpression, purification, crystallization and preliminary X-ray diffraction analysis of the receiver domain of PhoB

artículo científico publicado en 1998

Pancreatic procarboxypeptidases: oligomeric structures and activation processes revisited.

artículo científico publicado en 1997

Papaya glutamine cyclotransferase shows a singular five-fold beta-propeller architecture that suggests a novel reaction mechanism.

artículo científico publicado en 2006

Plasmid replication initiator RepB forms a hexamer reminiscent of ring helicases and has mobile nuclease domains

artículo científico publicado en 2009

Plasmid transcriptional repressor CopG oligomerises to render helical superstructures unbound and in complexes with oligonucleotides

artículo científico publicado en 2001

Purification, crystallization and preliminary X-ray diffraction of wild-type and mutant recombinant human transforming growth factor beta-induced protein (TGFBIp).

artículo científico publicado en 2009

Recombinant production of human α2-macroglobulin variants and interaction studies with recombinant G-related α2-macroglobulin binding protein and latent transforming growth factor-β2

scientific article published on 24 June 2019

Recombinant production, purification, crystallization, and structure analysis of human transforming growth factor β2 in a new conformation.

artículo científico publicado en 2019

Refined 2.0 A X-ray crystal structure of the snake venom zinc-endopeptidase adamalysin II. Primary and tertiary structure determination, refinement, molecular structure and comparison with astacin, collagenase and thermolysin

artículo científico publicado en 1994

Solving a 300 kDa multimeric protein by low-resolution MAD phasing and averaging/phase extension.

artículo científico publicado en 2001

Structural Basis for Latency and Function of Immune Inhibitor A Metallopeptidase, a Modulator of the Bacillus anthracis Secretome

artículo científico publicado en 2016

Structural and Functional Analyses Reveal That Staphylococcus aureus Antibiotic Resistance Factor HmrA Is a Zinc-dependent Endopeptidase

artículo científico publicado en 2011

Structural and Functional Implications of Human Transforming Growth Factor β-Induced Protein, TGFBIp, in Corneal Dystrophies

artículo científico publicado en 2017

Structural and functional insight into pan-endopeptidase inhibition by α2-macroglobulins

artículo científico publicado en 2017

Structural and functional insights into Escherichia coli α2-macroglobulin endopeptidase snap-trap inhibition

artículo científico publicado en 2015

Structural and functional probing of PorZ, an essential bacterial surface component of the type-IX secretion system of human oral-microbiomic Porphyromonas gingivalis.

artículo científico publicado en 2016

Structural aspects of the metzincin clan of metalloendopeptidases.

artículo científico publicado en 2003

Structural determinants of inhibition of Porphyromonas gingivalis gingipain K by KYT-36, a potent, selective, and bioavailable peptidase inhibitor.

artículo científico publicado en 2019

Structural insights unravel the zymogenic mechanism of the virulence factor gingipain K from Porphyromonas gingivalis, a causative agent of gum disease from the human oral microbiome

artículo científico publicado en 2017

Structure and mechanism of a bacterial host-protein citrullinating virulence factor, Porphyromonas gingivalis peptidylarginine deiminase

artículo científico publicado en 2015

Structure and mechanism of cysteine peptidase gingipain K (Kgp), a major virulence factor of Porphyromonas gingivalis in periodontitis.

artículo científico publicado en 2014

Structure and mechanism of metallocarboxypeptidases

artículo científico publicado en 2008

Structure and role of coupling proteins in conjugal DNA transfer.

artículo científico publicado en 2002

Structure of TrwB, a gatekeeper in bacterial conjugation

artículo científico publicado en 2001

Structure of astacin and implications for activation of astacins and zinc-ligation of collagenases

artículo científico publicado en 1992

Structure of mammalian plasma fetuin-B and its mechanism of selective metallopeptidase inhibition

artículo científico publicado en 2019

Structure of proline iminopeptidase from Xanthomonas campestris pv. citri: a prototype for the prolyl oligopeptidase family.

artículo científico publicado en 1998

Structure, function and latency regulation of a bacterial enterotoxin potentially derived from a mammalian adamalysin/ADAM xenolog

artículo científico publicado en 2011

Structure-Function Studies of the Staphylococcal Methicillin Resistance Antirepressor MecR2

artículo científico publicado en 2013

Structures of adamalysin II with peptidic inhibitors. Implications for the design of tumor necrosis factor α convertase inhibitors ⬇️

artículo científico publicado el 1 de febrero de 1998

Substrate specificity of a metalloprotease of the pappalysin family revealed by an inhibitor and a product complex

artículo científico publicado en 2007

Tandem DNA recognition by PhoB, a two-component signal transduction transcriptional activator

artículo científico publicado en 2002

The C-terminal region of human plasma fetuin-B is dispensable for the raised-elephant-trunk mechanism of inhibition of astacin metallopeptidases

scientific article published on 11 October 2019

The alpha-amylase from the yellow meal worm: complete primary structure, crystallization and preliminary X-ray analysis.

artículo científico

The bacterial conjugation protein TrwB resembles ring helicases and F1-ATPase

artículo científico publicado en 2001

The cofactor-induced pre-active conformation in PhoB.

artículo científico publicado en 2006

The crystal structure of human α2-macroglobulin reveals a unique molecular cage

artículo científico publicado en 2012

The eight-cysteine motif, a versatile structure in plant proteins.

artículo científico publicado en 2004

The matrix protein VP40 from Ebola virus octamerizes into pore-like structures with specific RNA binding properties

artículo científico publicado en 2003

The metzincin-superfamily of zinc-peptidases.

artículo científico publicado en 1996

The metzincins — Topological and sequential relations between the astacins, adamalysins, serralysins, and matrixins (collagenases) define a super family of zinc‐peptidases ⬇️

artículo científico publicado el 1 de mayo de 1995

The molecular analysis of Trypanosoma cruzi metallocarboxypeptidase 1 provides insight into fold and substrate specificity

artículo científico publicado en 2008

The pCri System: a vector collection for recombinant protein expression and purification

artículo científico publicado en 2014

The role of exon 5 in fibroblast collagenase (MMP-1) substrate specificity and inhibitor selectivity

artículo científico publicado en 2001

The structure of human prokallikrein 6 reveals a novel activation mechanism for the kallikrein family

artículo científico publicado en 2002

The structure of the catalytic domain of Tannerella forsythia karilysin reveals it is a bacterial xenologue of animal matrix metalloproteinases

artículo científico publicado en 2011

Third time lucky? Getting a grip on matrix metalloproteinases.

artículo científico publicado en 2017

Three-dimensional crystal structure of human eosinophil cationic protein (RNase 3) at 1.75 A resolution

artículo científico publicado en 2000

Three-dimensional crystal structure of the transcription factor PhoB receiver domain

artículo científico publicado en 1999

Two-wavelength MAD phasing: in search of the optimal choice of wavelengths

artículo científico publicado en 1999

Unbound and acylated structures of the MecR1 extracellular antibiotic-sensor domain provide insights into the signal-transduction system that triggers methicillin resistance

artículo científico publicado en 2006

α2-Macroglobulins: Structure and Function

artículo científico publicado en 2017

Lista de obras de Gomis-Rüth FX

1.8‐Å Crystal Structure of the Catalytic Domain of Human Neutrophil Collagenase (Matrix Metalloproteinase‐8) Complexed with a Peptidomimetic Hydroxamate Primed‐Side Inhibitor with a Distinct Selectivity Profile ⬇️

2 angstrom X-ray structure of adamalysin II complexed with a peptide phosphonate inhibitor adopting a retro-binding mode

A Novel Family of Soluble Minimal Scaffolds Provides Structural Insight into the Catalytic Domains of Integral Membrane Metallopeptidases

A different look for AB5 toxins.

A novel mechanism of latency in matrix metalloproteinases

A novel strategy for inhibition of α-amylases: yellow meal worm α-amylase in complex with the Ragi bifunctional inhibitor at 2.5 å resolution ⬇️

A standard orientation for metallopeptidases ⬇️

A structure-derived snap-trap mechanism of a multispecific serpin from the dysbiotic human oral microbiome

Activity of ulilysin, an archaeal PAPP-A-related gelatinase and IGFBP protease.

Architecture and function of metallopeptidase catalytic domains

Astacins, serralysins, snake venom and matrix metalloproteinases exhibit identical zinc-binding environments (HEXXHXXGXXH and Met-turn) and topologies and should be grouped into a common family, the 'metzincins'

Catalytic domain architecture of metzincin metalloproteases.

Caught after the Act: a human A-type metallocarboxypeptidase in a product complex with a cleaved hexapeptide

Crystal structure analysis, refinement and enzymatic reaction mechanism of N-carbamoylsarcosine amidohydrolase from Arthrobacter sp. at 2.0 A resolution

Crystal structure of an oligomer of proteolytic zymogens: detailed conformational analysis of the bovine ternary complex and implications for their activation 1 1Edited by I. A. Wilson

Crystal structure of yellow meal worm α-amylase at 1.64 Å resolution ⬇️

Crystal structures, spectroscopic features, and catalytic properties of cobalt(II), copper(II), nickel(II), and mercury(II) derivatives of the zinc endopeptidase astacin. A correlation of structure and proteolytic activity

Crystallization and preliminary X-ray analysis of the ternary complex of procarboxypeptidase A from bovine pancreas

Crystallization and preliminary X-ray diffraction analysis of eukaryotic α2 -macroglobulin family members modified by methylamine, proteases and glycosidases

Crystallization and preliminary X-ray diffraction analysis of proline iminopeptidase from Xanthomonas campestris pv. citri

Cut and move: protein machinery for DNA processing in bacterial conjugation.

Cutting at the right place. The importance of selective limited proteolysis in the activation of proproteinase E

De novo design of immunoglobulin-like domains

Detailed architecture of a DNA translocating machine: the high-resolution structure of the bacteriophage phi29 connector particle

Determination of hemihedral twinning and initial structural analysis of crystals of the procarboxypeptidase A ternary complex

Enzymatic and Structural Characterization of the Major Endopeptidase in the Venus Flytrap Digestion Fluid.

Escherichia coli dihydrodipicolinate synthase. Identification of the active site and crystallization ⬇️

Expression and purification of integral membrane metallopeptidase HtpX.

First structure of a snake venom metalloproteinase: a prototype for matrix metalloproteinases/collagenases

Human procarboxypeptidase B: three-dimensional structure and implications for thrombin-activatable fibrinolysis inhibitor (TAFI)

Inhibition of carboxypeptidase A by excess zinc: analysis of the structural determinants by X-ray crystallography

Insights into MMP-TIMP interactions.

Insights into the molecular inactivation mechanism of human activated thrombin-activatable fibrinolysis inhibitor

Mammalian metallopeptidase inhibition at the defense barrier of Ascaris parasite

Matrix metalloproteinases outside vertebrates

Matrix metalloproteinases: fold and function of their catalytic domains

Mechanism of inhibition of the human matrix metalloproteinase stromelysin-1 by TIMP-1 ⬇️

Multiple Architectures and Mechanisms of Latency in Metallopeptidase Zymogens

Multiple stable conformations account for reversible concentration-dependent oligomerization and autoinhibition of a metamorphic metallopeptidase

On the Relevance of the Met-turn Methionine in Metzincins

Overexpression, purification, crystallization and preliminary X-ray diffraction analysis of the pMV158-encoded plasmid transcriptional repressor protein CopG

Overexpression, purification, crystallization and preliminary X-ray diffraction analysis of the receiver domain of PhoB

Pancreatic procarboxypeptidases: oligomeric structures and activation processes revisited.

Papaya glutamine cyclotransferase shows a singular five-fold beta-propeller architecture that suggests a novel reaction mechanism.

Plasmid replication initiator RepB forms a hexamer reminiscent of ring helicases and has mobile nuclease domains

Plasmid transcriptional repressor CopG oligomerises to render helical superstructures unbound and in complexes with oligonucleotides

Purification, crystallization and preliminary X-ray diffraction of wild-type and mutant recombinant human transforming growth factor beta-induced protein (TGFBIp).

Recombinant production of human α2-macroglobulin variants and interaction studies with recombinant G-related α2-macroglobulin binding protein and latent transforming growth factor-β2

Recombinant production, purification, crystallization, and structure analysis of human transforming growth factor β2 in a new conformation.

Refined 2.0 A X-ray crystal structure of the snake venom zinc-endopeptidase adamalysin II. Primary and tertiary structure determination, refinement, molecular structure and comparison with astacin, collagenase and thermolysin

Solving a 300 kDa multimeric protein by low-resolution MAD phasing and averaging/phase extension.

Structural Basis for Latency and Function of Immune Inhibitor A Metallopeptidase, a Modulator of the Bacillus anthracis Secretome

Structural and Functional Analyses Reveal That Staphylococcus aureus Antibiotic Resistance Factor HmrA Is a Zinc-dependent Endopeptidase

Structural and Functional Implications of Human Transforming Growth Factor β-Induced Protein, TGFBIp, in Corneal Dystrophies

Structural and functional insight into pan-endopeptidase inhibition by α2-macroglobulins

Structural and functional insights into Escherichia coli α2-macroglobulin endopeptidase snap-trap inhibition

Structural and functional probing of PorZ, an essential bacterial surface component of the type-IX secretion system of human oral-microbiomic Porphyromonas gingivalis.

Structural aspects of the metzincin clan of metalloendopeptidases.

Structural determinants of inhibition of Porphyromonas gingivalis gingipain K by KYT-36, a potent, selective, and bioavailable peptidase inhibitor.

Structural insights unravel the zymogenic mechanism of the virulence factor gingipain K from Porphyromonas gingivalis, a causative agent of gum disease from the human oral microbiome

Structure and mechanism of a bacterial host-protein citrullinating virulence factor, Porphyromonas gingivalis peptidylarginine deiminase

Structure and mechanism of cysteine peptidase gingipain K (Kgp), a major virulence factor of Porphyromonas gingivalis in periodontitis.

Structure and mechanism of metallocarboxypeptidases

Structure and role of coupling proteins in conjugal DNA transfer.

Structure of TrwB, a gatekeeper in bacterial conjugation

Structure of astacin and implications for activation of astacins and zinc-ligation of collagenases

Structure of mammalian plasma fetuin-B and its mechanism of selective metallopeptidase inhibition

Structure of proline iminopeptidase from Xanthomonas campestris pv. citri: a prototype for the prolyl oligopeptidase family.

Structure, function and latency regulation of a bacterial enterotoxin potentially derived from a mammalian adamalysin/ADAM xenolog

Structure-Function Studies of the Staphylococcal Methicillin Resistance Antirepressor MecR2

Structures of adamalysin II with peptidic inhibitors. Implications for the design of tumor necrosis factor α convertase inhibitors ⬇️

Substrate specificity of a metalloprotease of the pappalysin family revealed by an inhibitor and a product complex

Tandem DNA recognition by PhoB, a two-component signal transduction transcriptional activator

The C-terminal region of human plasma fetuin-B is dispensable for the raised-elephant-trunk mechanism of inhibition of astacin metallopeptidases

The alpha-amylase from the yellow meal worm: complete primary structure, crystallization and preliminary X-ray analysis.

The bacterial conjugation protein TrwB resembles ring helicases and F1-ATPase

The cofactor-induced pre-active conformation in PhoB.

The crystal structure of human α2-macroglobulin reveals a unique molecular cage

The eight-cysteine motif, a versatile structure in plant proteins.