Lista de obras - K Miyazawa - Dominio Público Uruguay

A Smad3 and TTF-1/NKX2-1 complex regulates Smad4-independent gene expression.

artículo científico publicado en 2014

A comparative analysis of Smad-responsive motifs identifies multiple regulatory inputs for TGF-β transcriptional activation

scientific article published on 03 September 2019

A deubiquitinating enzyme UBPY interacts with the Src homology 3 domain of Hrs-binding protein via a novel binding motif PX(V/I)(D/N)RXXKP

artículo científico publicado en 2000

A negative regulator or just an unconcerned passerby: phosphoinositide 3-kinase signalling in IL-12 production

scientific article published on 16 October 2012

A scaffold protein JIP-1b enhances amyloid precursor protein phosphorylation by JNK and its association with kinesin light chain 1.

artículo científico publicado en 2003

Activation of MET receptor tyrosine kinase in ulcer surface epithelial cells undergoing restitution.

artículo científico publicado en 2008

Activation of hepatocyte growth factor by two homologous proteases, blood-coagulation factor XIIa and hepatocyte growth factor activator

artículo científico publicado en 1995

Activation of hepatocyte growth factor in monkey stomach following gastric mucosal injury.

artículo científico publicado en 2004

Activation of hepatocyte growth factor in the injured tissues is mediated by hepatocyte growth factor activator.

artículo científico publicado en 1996

An Id-like molecule, HHM, is a synexpression group-restricted regulator of TGF-beta signalling

artículo científico publicado en 2008

An alternatively processed mRNA generated from human hepatocyte growth factor gene.

artículo científico publicado en 1991

Arkadia amplifies TGF-beta superfamily signalling through degradation of Smad7

artículo científico publicado en 2003

Arkadia complexes with clathrin adaptor AP2 and regulates EGF signalling.

artículo científico publicado en 2010

Arkadia enhances BMP signalling through ubiquitylation and degradation of Smad6

artículo científico publicado en 2015

Autocrine TGF-beta signaling maintains tumorigenicity of glioma-initiating cells through Sry-related HMG-box factors.

artículo científico publicado en 2009

Basolateral BMP Signaling in Polarized Epithelial Cells ⬇️

artículo científico publicado el 13 de mayo de 2013

Characterization of hepatocyte-growth-factor receptors on Meth A cells

artículo científico publicado en 1992

Characterization of the promoter region of the rat hepatocyte-growth-factor/scatter-factor gene.

artículo científico publicado en 1993

Chromatin immunoprecipitation on microarray analysis of Smad2/3 binding sites reveals roles of ETS1 and TFAP2A in transforming growth factor beta signaling.

artículo científico publicado en 2008

Context-dependent regulation of the expression of c-Ski protein by Arkadia in human cancer cells.

artículo científico publicado en 2009

Crystallization and preliminary X-ray diffraction analysis of GCIP/HHM transcriptional regulator.

artículo científico publicado en 2008

Deubiquitylase USP25 prevents degradation of BCR-ABL protein and ensures proliferation of Ph-positive leukemia cells

artículo científico publicado en 2020

Dissociation of c-fos induction and mitogen-activated-protein kinase activation from the hepatocyte-growth-factor-induced motility response in human gastric carcinoma cells.

artículo científico publicado en 1996

Dissociation of the AhR-ARNT complex by TGF-β-Smad signaling represses CYP1A1 gene expression and inhibits benze[a]pyrene-mediated cytotoxicity

artículo científico publicado en 2020

Dual Roles for Epithelial Splicing Regulatory Proteins 1 (ESRP1) and 2 (ESRP2) in Cancer Progression

artículo científico publicado en 2016

Encountering unpredicted off-target effects of pharmacological inhibitors ⬇️

artículo científico publicado el 9 de mayo de 2011

Epithelial splicing regulatory proteins 1 (ESRP1) and 2 (ESRP2) suppress cancer cell motility via different mechanisms.

artículo científico publicado en 2014

Ets1 and ESE1 reciprocally regulate expression of ZEB1/ZEB2, dependent on ERK1/2 activity, in breast cancer cells

artículo científico publicado en 2017

Exogenously administered HGF activator augments liver regeneration through the production of biologically active HGF.

artículo científico publicado en 2002

Expression of ZEBs in gliomas is associated with invasive properties and histopathological grade.

artículo científico publicado en 2018

Functional characterization of Kunitz domains in hepatocyte growth factor activator inhibitor type 1.

artículo científico publicado en 2002

Functional characterization of human hepatocyte growth factor mutants obtained by deletion of structural domains

artículo científico publicado el 13 de octubre de 1992

Functional in vivo optical imaging of tumor angiogenesis, growth, and metastasis prevented by administration of anti-human VEGF antibody in xenograft model of human fibrosarcoma HT1080 cells.

artículo científico publicado en 2009

Glioma-initiating cells retain their tumorigenicity through integration of the Sox axis and Oct4 protein

artículo científico publicado en 2011

Hepatocyte growth factor (HGF)-induced cell migration is negatively modulated by epidermal growth factor through tyrosine phosphorylation of the HGF receptor

scientific article published on 01 March 1996

Hepatocyte growth factor activator (HGFA): a serine protease that links tissue injury to activation of hepatocyte growth factor.

scientific article published on 02 April 2010

Hepatocyte growth factor activator inhibitor type 1 (HAI-1) is required for branching morphogenesis in the chorioallantoic placenta

scientific journal article

Hepatocyte growth factor activator inhibitor type 1 is a specific cell surface binding protein of hepatocyte growth factor activator (HGFA) and regulates HGFA activity in the pericellular microenvironment

artículo científico publicado en 2000

Hepatocyte growth factor and transforming growth factor-beta stimulate both cell growth and migration of human gastric adenocarcinoma cells

artículo científico publicado el 1 de junio de 1992

Hepatocyte growth factor remains as an inactive single chain after partial hepatectomy or unilateral nephrectomy

artículo científico publicado en 1995

Identification of a 190-kDa vascular endothelial growth factor 165 cell surface binding protein on a human glioma cell line.

artículo científico publicado en 1997

Identification of hepatocyte growth factor activator inhibitor type 2 (HAI-2)-related small peptide (H2RSP): its nuclear localization and generation of chimeric mRNA transcribed from both HAI-2 and H2RSP genes

artículo científico publicado en 2001

Identification of integrin α3 as a molecular marker of cells undergoing epithelial–mesenchymal transition and of cancer cells with aggressive phenotypes ⬇️

artículo científico publicado el 20 de julio de 2013

Impairment of activation of hepatocyte growth factor precursor into its mature form in rats with liver cirrhosis.

artículo científico publicado en 2002

Induction of hepatocyte growth factor activator messenger RNA in the liver following tissue injury and acute inflammation

artículo científico publicado en 1997

Interaction with Smad4 is indispensable for suppression of BMP signaling by c-Ski

artículo científico publicado en 2004

Involvement of down-regulation of Cdk2 activity in hepatocyte growth factor-induced cell cycle arrest at G1 in the human hepatocellular carcinoma cell line HepG2.

artículo científico publicado en 2004

Maid is a negative regulator of transforming growth factor-β-induced cell migration.

artículo científico publicado en 2015

Molecular cloning and characterization of a novel protein serine/threonine kinase highly expressed in mouse embryo.

artículo científico publicado en 1998

Mouse hepatocyte growth factor activator gene: its expression not only in the liver but also in the gastrointestinal tract.

artículo científico publicado en 2000

Negative regulation of transforming growth factor-beta (TGF-beta) signaling by WW domain-containing protein 1 (WWP1)

artículo científico publicado en 2004

Nuclear and cytoplasmic c-Ski differently modulate cellular functions

artículo científico publicado en 2006

Oligodendrocyte transcription factor 1 (Olig1) is a Smad cofactor involved in cell motility induced by transforming growth factor-β.

artículo científico publicado en 2013

Phosphoinositide 5-phosphatases: How do they affect tumourigenesis?

artículo científico publicado en 2012

Phosphorylation in the activation loop as the finishing touch in c-Kit activation ⬇️

artículo científico publicado el 20 de marzo de 2012

Pin1 down-regulates transforming growth factor-beta (TGF-beta) signaling by inducing degradation of Smad proteins

artículo científico publicado en 2009

Production and activation of hepatocyte growth factor during the healing of rat gastric ulcers

scientific article published on 01 January 1997

RB1CC1 Protein Positively Regulates Transforming Growth Factor-β Signaling through the Modulation of Arkadia E3 Ubiquitin Ligase Activity ⬇️

artículo científico publicado el 27 de julio de 2011

Ras signaling directs endothelial specification of VEGFR2+ vascular progenitor cells.

artículo científico publicado en 2008

Reciprocal expression of Slug and Snail in human oral cancer cells

artículo científico publicado en 2018

Regeneration of injured intestinal mucosa is impaired in hepatocyte growth factor activator-deficient mice.

artículo científico publicado en 2004

Regulation of TGF-β Family Signaling by Inhibitory Smads.

artículo científico publicado en 2016

Repression of Smad3 by Stat3 and c-Ski/SnoN induces gefitinib resistance in lung adenocarcinoma.

artículo científico publicado en 2017

Role of immunoglobulin-like domains 2-4 of the platelet-derived growth factor alpha-receptor in ligand-receptor complex assembly

artículo científico publicado en 1998

SB-431542 and Gleevec inhibit transforming growth factor-beta-induced proliferation of human osteosarcoma cells

artículo científico publicado en 2003

STAT3 integrates cooperative Ras and TGF-β signals that induce Snail expression

artículo científico publicado en 2015

SUMO amplifies TGF-beta signalling

artículo científico publicado en 2008

Selective inhibitory effects of Smad6 on bone morphogenetic protein type I receptors

scientific article published on 10 May 2007

Smad3-STAT3 crosstalk in pathophysiological contexts.

artículo científico publicado en 2017

Smad7 inhibits transforming growth factor-beta family type i receptors through two distinct modes of interaction.

artículo científico publicado en 2010

Smurf2 induces ubiquitin-dependent degradation of Smurf1 to prevent migration of breast cancer cells

artículo científico publicado en 2008

Snail suppresses cellular senescence and promotes fibroblast-led cancer cell invasion

artículo científico publicado en 2017

Specificity of the inhibitory effects of Dad on TGF-beta family type I receptors, Thickveins, Saxophone, and Baboon in Drosophila.

artículo científico publicado en 2008

Stimulation of prostaglandin production by hepatocyte growth factor in human gastric carcinoma cells

artículo científico publicado en 1993

Structural insight into modest binding of a non-PXXP ligand to the signal transducing adaptor molecule-2 Src homology 3 domain

artículo científico publicado en 2003

Structural organization and chromosomal localization of the human hepatocyte growth factor activator gene--phylogenetic and functional relationship with blood coagulation factor XII, urokinase, and tissue-type plasminogen activator.

artículo científico publicado en 1998

Structural organization and the transcription initiation site of the human hepatocyte growth factor gene ⬇️

artículo científico publicado el 24 de septiembre de 1991

Suppression of p53 activity through the cooperative action of Ski and histone deacetylase SIRT1.

artículo científico publicado en 2010

TGF-β drives epithelial-mesenchymal transition through δEF1-mediated downregulation of ESRP.

artículo científico publicado en 2011

TGF-β regulates isoform switching of FGF receptors and epithelial-mesenchymal transition

scientific journal article

The potential role of regulator of G-protein signaling 16 in cell motility mediated by δEF1 family proteins.

artículo científico publicado en 2016

Transcriptional and post-transcriptional regulation in TGF-β-mediated epithelial-mesenchymal transition.

artículo científico publicado en 2012

Transforming growth factor-beta promotes survival of mammary carcinoma cells through induction of antiapoptotic transcription factor DEC1

scientific article published on 01 October 2007

Two major Smad pathways in TGF-beta superfamily signalling.

artículo científico publicado en 2002

Two short segments of Smad3 are important for specific interaction of Smad3 with c-Ski and SnoN

artículo científico publicado en 2002

VEGFR2-PLCgamma1 axis is essential for endothelial specification of VEGFR2+ vascular progenitor cells.

artículo científico publicado en 2009

ZEB1 and oncogenic Ras constitute a regulatory switch for stimulus-dependent E-cadherin downregulation

artículo científico publicado en 2020

c-Met activation in lung adenocarcinoma tissues: an immunohistochemical analysis.

artículo científico publicado en 2007

c-Ski activates MyoD in the nucleus of myoblastic cells through suppression of histone deacetylases

scientific journal article

c-Ski inhibits the TGF-beta signaling pathway through stabilization of inactive Smad complexes on Smad-binding elements

artículo científico publicado en 2004

δEF1 associates with DNMT1 and maintains DNA methylation of the E-cadherin promoter in breast cancer cells

artículo científico publicado en 2014

Lista de obras de K Miyazawa

A Smad3 and TTF-1/NKX2-1 complex regulates Smad4-independent gene expression.

A comparative analysis of Smad-responsive motifs identifies multiple regulatory inputs for TGF-β transcriptional activation

A deubiquitinating enzyme UBPY interacts with the Src homology 3 domain of Hrs-binding protein via a novel binding motif PX(V/I)(D/N)RXXKP

A negative regulator or just an unconcerned passerby: phosphoinositide 3-kinase signalling in IL-12 production

A scaffold protein JIP-1b enhances amyloid precursor protein phosphorylation by JNK and its association with kinesin light chain 1.

Activation of MET receptor tyrosine kinase in ulcer surface epithelial cells undergoing restitution.

Activation of hepatocyte growth factor by two homologous proteases, blood-coagulation factor XIIa and hepatocyte growth factor activator

Activation of hepatocyte growth factor in monkey stomach following gastric mucosal injury.

Activation of hepatocyte growth factor in the injured tissues is mediated by hepatocyte growth factor activator.

An Id-like molecule, HHM, is a synexpression group-restricted regulator of TGF-beta signalling

An alternatively processed mRNA generated from human hepatocyte growth factor gene.

Arkadia amplifies TGF-beta superfamily signalling through degradation of Smad7

Arkadia complexes with clathrin adaptor AP2 and regulates EGF signalling.

Arkadia enhances BMP signalling through ubiquitylation and degradation of Smad6

Autocrine TGF-beta signaling maintains tumorigenicity of glioma-initiating cells through Sry-related HMG-box factors.

Basolateral BMP Signaling in Polarized Epithelial Cells ⬇️

Characterization of hepatocyte-growth-factor receptors on Meth A cells

Characterization of the promoter region of the rat hepatocyte-growth-factor/scatter-factor gene.

Chromatin immunoprecipitation on microarray analysis of Smad2/3 binding sites reveals roles of ETS1 and TFAP2A in transforming growth factor beta signaling.

Context-dependent regulation of the expression of c-Ski protein by Arkadia in human cancer cells.

Crystallization and preliminary X-ray diffraction analysis of GCIP/HHM transcriptional regulator.

Deubiquitylase USP25 prevents degradation of BCR-ABL protein and ensures proliferation of Ph-positive leukemia cells

Dissociation of c-fos induction and mitogen-activated-protein kinase activation from the hepatocyte-growth-factor-induced motility response in human gastric carcinoma cells.

Dissociation of the AhR-ARNT complex by TGF-β-Smad signaling represses CYP1A1 gene expression and inhibits benze[a]pyrene-mediated cytotoxicity

Dual Roles for Epithelial Splicing Regulatory Proteins 1 (ESRP1) and 2 (ESRP2) in Cancer Progression

Encountering unpredicted off-target effects of pharmacological inhibitors ⬇️

Epithelial splicing regulatory proteins 1 (ESRP1) and 2 (ESRP2) suppress cancer cell motility via different mechanisms.

Ets1 and ESE1 reciprocally regulate expression of ZEB1/ZEB2, dependent on ERK1/2 activity, in breast cancer cells

Exogenously administered HGF activator augments liver regeneration through the production of biologically active HGF.

Expression of ZEBs in gliomas is associated with invasive properties and histopathological grade.

Functional characterization of Kunitz domains in hepatocyte growth factor activator inhibitor type 1.

Functional characterization of human hepatocyte growth factor mutants obtained by deletion of structural domains

Functional in vivo optical imaging of tumor angiogenesis, growth, and metastasis prevented by administration of anti-human VEGF antibody in xenograft model of human fibrosarcoma HT1080 cells.

Glioma-initiating cells retain their tumorigenicity through integration of the Sox axis and Oct4 protein

Hepatocyte growth factor (HGF)-induced cell migration is negatively modulated by epidermal growth factor through tyrosine phosphorylation of the HGF receptor

Hepatocyte growth factor activator (HGFA): a serine protease that links tissue injury to activation of hepatocyte growth factor.

Hepatocyte growth factor activator inhibitor type 1 (HAI-1) is required for branching morphogenesis in the chorioallantoic placenta

Hepatocyte growth factor activator inhibitor type 1 is a specific cell surface binding protein of hepatocyte growth factor activator (HGFA) and regulates HGFA activity in the pericellular microenvironment

Hepatocyte growth factor and transforming growth factor-beta stimulate both cell growth and migration of human gastric adenocarcinoma cells

Hepatocyte growth factor remains as an inactive single chain after partial hepatectomy or unilateral nephrectomy

Identification of a 190-kDa vascular endothelial growth factor 165 cell surface binding protein on a human glioma cell line.

Identification of hepatocyte growth factor activator inhibitor type 2 (HAI-2)-related small peptide (H2RSP): its nuclear localization and generation of chimeric mRNA transcribed from both HAI-2 and H2RSP genes

Identification of integrin α3 as a molecular marker of cells undergoing epithelial–mesenchymal transition and of cancer cells with aggressive phenotypes ⬇️

Impairment of activation of hepatocyte growth factor precursor into its mature form in rats with liver cirrhosis.

Induction of hepatocyte growth factor activator messenger RNA in the liver following tissue injury and acute inflammation

Interaction with Smad4 is indispensable for suppression of BMP signaling by c-Ski

Involvement of down-regulation of Cdk2 activity in hepatocyte growth factor-induced cell cycle arrest at G1 in the human hepatocellular carcinoma cell line HepG2.

Maid is a negative regulator of transforming growth factor-β-induced cell migration.

Molecular cloning and characterization of a novel protein serine/threonine kinase highly expressed in mouse embryo.

Mouse hepatocyte growth factor activator gene: its expression not only in the liver but also in the gastrointestinal tract.

Negative regulation of transforming growth factor-beta (TGF-beta) signaling by WW domain-containing protein 1 (WWP1)

Nuclear and cytoplasmic c-Ski differently modulate cellular functions

Oligodendrocyte transcription factor 1 (Olig1) is a Smad cofactor involved in cell motility induced by transforming growth factor-β.

Phosphoinositide 5-phosphatases: How do they affect tumourigenesis?

Phosphorylation in the activation loop as the finishing touch in c-Kit activation ⬇️

Pin1 down-regulates transforming growth factor-beta (TGF-beta) signaling by inducing degradation of Smad proteins

Production and activation of hepatocyte growth factor during the healing of rat gastric ulcers

RB1CC1 Protein Positively Regulates Transforming Growth Factor-β Signaling through the Modulation of Arkadia E3 Ubiquitin Ligase Activity ⬇️

Ras signaling directs endothelial specification of VEGFR2+ vascular progenitor cells.

Reciprocal expression of Slug and Snail in human oral cancer cells

Regeneration of injured intestinal mucosa is impaired in hepatocyte growth factor activator-deficient mice.

Regulation of TGF-β Family Signaling by Inhibitory Smads.

Repression of Smad3 by Stat3 and c-Ski/SnoN induces gefitinib resistance in lung adenocarcinoma.

Role of immunoglobulin-like domains 2-4 of the platelet-derived growth factor alpha-receptor in ligand-receptor complex assembly

SB-431542 and Gleevec inhibit transforming growth factor-beta-induced proliferation of human osteosarcoma cells

STAT3 integrates cooperative Ras and TGF-β signals that induce Snail expression

SUMO amplifies TGF-beta signalling

Selective inhibitory effects of Smad6 on bone morphogenetic protein type I receptors

Smad3-STAT3 crosstalk in pathophysiological contexts.

Smad7 inhibits transforming growth factor-beta family type i receptors through two distinct modes of interaction.

Smurf2 induces ubiquitin-dependent degradation of Smurf1 to prevent migration of breast cancer cells

Snail suppresses cellular senescence and promotes fibroblast-led cancer cell invasion

Specificity of the inhibitory effects of Dad on TGF-beta family type I receptors, Thickveins, Saxophone, and Baboon in Drosophila.

Stimulation of prostaglandin production by hepatocyte growth factor in human gastric carcinoma cells

Structural insight into modest binding of a non-PXXP ligand to the signal transducing adaptor molecule-2 Src homology 3 domain

Structural organization and chromosomal localization of the human hepatocyte growth factor activator gene--phylogenetic and functional relationship with blood coagulation factor XII, urokinase, and tissue-type plasminogen activator.

Structural organization and the transcription initiation site of the human hepatocyte growth factor gene ⬇️

Suppression of p53 activity through the cooperative action of Ski and histone deacetylase SIRT1.

TGF-β drives epithelial-mesenchymal transition through δEF1-mediated downregulation of ESRP.