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Lista de obras de Mark J. Henderson

A Comparative Study of Target Engagement Assays for HDAC1 Inhibitor Profiling

scientific article published on 29 October 2019

A Low Affinity GCaMP3 Variant (GCaMPer) for Imaging the Endoplasmic Reticulum Calcium Store

artículo científico publicado en 2015

A high-throughput screening to identify small molecules that suppress huntingtin promoter activity or activate huntingtin-antisense promoter activity

artículo científico publicado en 2021

A small molecule inhibitor of ER-to-cytosol protein dislocation exhibits anti-dengue and anti-Zika virus activity

artículo científico publicado en 2019

A widely-applicable high-throughput cellular thermal shift assay (CETSA) using split Nano Luciferase.

artículo científico publicado en 2018

Compound screening in cell-based models of tau inclusion formation: Comparison of primary neuron and HEK293 cell assays

artículo científico publicado en 2020

Design, Synthesis, and Biological Evaluation of Quinazolin-4-one-Based Hydroxamic Acids as Dual PI3K/HDAC Inhibitors

artículo científico publicado en 2020

Discovery of endoplasmic reticulum calcium stabilizers to rescue ER-stressed podocytes in nephrotic syndrome

scientific article published on 24 June 2019

High-Throughput Cellular Thermal Shift Assays in Research and Drug Discovery

scientific article published on 30 September 2019

High-throughput screening with nucleosome substrate identifies small-molecule inhibitors of the human histone lysine methyltransferase NSD2

artículo científico publicado en 2018

Insights into the Action of Inhibitor Enantiomers against Histone Lysine Demethylase 5A.

artículo científico publicado en 2018

Ipomoeassin F Binds Sec61α to Inhibit Protein Translocation

scientific article published on 15 May 2019

KDEL Receptors Are Differentially Regulated to Maintain the ER Proteome under Calcium Deficiency

scientific article published on 01 November 2018

KDM5 histone demethylases repress immune response via suppression of STING

artículo científico publicado en 2018

Longitudinal monitoring of Gaussia and Nano luciferase activities to concurrently assess ER calcium homeostasis and ER stress in vivo

artículo científico publicado en 2017

Mesencephalic astrocyte-derived neurotrophic factor (MANF) secretion and cell surface binding are modulated by KDEL receptors.

artículo científico publicado en 2012

Monitoring Endoplasmic Reticulum Calcium Homeostasis Using a Gaussia Luciferase SERCaMP.

artículo científico publicado en 2015

Near-infrared fluorescent protein iRFP713 as a reporter protein for optogenetic vectors, a transgenic Cre-reporter rat, and other neuronal studies

artículo científico publicado en 2017

Neurons Internalize Functionalized Micron-Sized Silicon Dioxide Microspheres.

artículo científico publicado en 2017

Optogenetic inhibition of dorsal medial prefrontal cortex attenuates stress-induced reinstatement of palatable food seeking in female rats

artículo científico publicado en 2013

Physiologically relevant orthogonal assays for the discovery of small-molecule modulators of WIP1 phosphatase in high-throughput screens

scientific article published on 03 September 2019

SERCaMP: a carboxy-terminal protein modification that enables monitoring of ER calcium homeostasis

artículo científico publicado en 2014

Structure-based engineering of irreversible inhibitors against histone lysine demethylase KDM5A

artículo científico publicado en 2018

The SARS-CoV-2 Cytopathic Effect Is Blocked by Lysosome Alkalizing Small Molecules

artículo científico publicado en 2020

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