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Lista de obras de R.W. Sanders

A New Glycan-Dependent CD4-Binding Site Neutralizing Antibody Exerts Pressure on HIV-1 In Vivo

artículo científico publicado en 2015

A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield

artículo científico publicado en 2011

A chimeric HIV-1 envelope glycoprotein trimer with an embedded granulocyte-macrophage colony-stimulating factor (GM-CSF) domain induces enhanced antibody and T cell responses

artículo científico publicado en 2011

A native-like SOSIP.664 trimer based on an HIV-1 subtype B env gene

artículo científico publicado en 2015

A next-generation cleaved, soluble HIV-1 Env trimer, BG505 SOSIP.664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies

artículo científico publicado en 2013

A recombinant human immunodeficiency virus type 1 envelope glycoprotein complex stabilized by an intermolecular disulfide bond between the gp120 and gp41 subunits is an antigenic mimic of the trimeric virion-associated structure

artículo científico publicado en 2000

A single mutation in Taiwanese H6N1 influenza hemagglutinin switches binding to human-type receptors.

artículo científico publicado en 2017

A stabilized HIV-1 envelope glycoprotein trimer fused to CD40 ligand targets and activates dendritic cells

artículo científico publicado en 2011

ADS-J1 inhibits HIV-1 infection and membrane fusion by targeting the highly conserved pocket in the gp41 NHR-trimer

artículo científico publicado en 2014

Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans.

artículo científico publicado en 2015

Afucosylated IgG characterizes enveloped viral responses and correlates with COVID-19 severity

scientific article published on 23 December 2020

Afucosylated immunoglobulin G responses are a hallmark of enveloped virus infections and show an exacerbated phenotype in COVID-19

artículo científico publicado en 2020

An Alternative Binding Mode of IGHV3-53 Antibodies to the SARS-CoV-2 Receptor Binding Domain

artículo científico publicado en 2020

An HIV-1 antibody from an elite neutralizer implicates the fusion peptide as a site of vulnerability

artículo científico publicado en 2016

An HIV-1 envelope glycoprotein trimer with an embedded IL-21 domain activates human B cells

artículo científico publicado en 2013

An alternative binding mode of IGHV3-53 antibodies to the SARS-CoV-2 receptor binding domain

artículo científico publicado en 2020

Antibodies to HIV-1: aiming at the right target

scientific article published on 12 June 2007

Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike

artículo científico publicado en 2015

Antibody Responses Elicited by Immunization with BG505 Trimer Immune Complexes

artículo científico publicado en 2019

Antibody potency relates to the ability to recognize the closed, pre-fusion form of HIV Env

artículo científico publicado en 2015

Asymmetric recognition of the HIV-1 trimer by broadly neutralizing antibody PG9.

artículo científico publicado en 2013

Autoantibodies induced by chimeric cytokine-HIV envelope glycoprotein immunogens.

artículo científico publicado en 2014

Autologous Antibody Responses to an HIV Envelope Glycan Hole Are Not Easily Broadened in Rabbits

scientific article published on 17 March 2020

Binding of inferred germline precursors of broadly neutralizing HIV-1 antibodies to native-like envelope trimers.

artículo científico publicado en 2015

Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface

artículo científico publicado en 2014

Broadly Neutralizing Antibody PGT121 Allosterically Modulates CD4 Binding via Recognition of the HIV-1 gp120 V3 Base and Multiple Surrounding Glycans

artículo científico publicado en 2013

Broadly neutralising antibodies in post-treatment control

scientific article published on 15 April 2019

Broadly neutralizing HIV antibodies define a glycan-dependent epitope on the prefusion conformation of gp41 on cleaved envelope trimers

artículo científico publicado en 2014

Broadly neutralizing antibodies against HIV-1: templates for a vaccine

artículo científico

CD4-induced activation in a soluble HIV-1 Env trimer

artículo científico publicado en 2014

Capturing the inherent structural dynamics of the HIV-1 envelope glycoprotein fusion peptide

artículo científico publicado en 2019

Chemical Cross-Linking Stabilizes Native-Like HIV-1 Envelope Glycoprotein Trimer Antigens

artículo científico publicado en 2015

Chimeric HIV-1 envelope glycoproteins with potent intrinsic granulocyte-macrophage colony-stimulating factor (GM-CSF) activity

artículo científico publicado en 2013

Cleavage strongly influences whether soluble HIV-1 envelope glycoprotein trimers adopt a native-like conformation

artículo científico publicado en 2013

Clinical adjuvant combinations stimulate potent B-cell responses in vitro by activating dermal dendritic cells

artículo científico publicado en 2013

Clinical evaluation of a soluble trimeric HIV-1 envelope glycoprotein vaccine

artículo científico publicado en 2011

Closing and opening holes in the glycan shield of HIV-1 envelope glycoprotein SOSIP trimers can redirect the neutralizing antibody response to the newly unmasked epitopes

article

Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller

artículo científico publicado en 2017

Colorectal mucus binds DC-SIGN and inhibits HIV-1 trans-infection of CD4+ T-lymphocytes

artículo científico publicado en 2015

Comparative Immunogenicity of Evolved V1V2-Deleted HIV-1 Envelope Glycoprotein Trimers

artículo científico publicado en 2013

Comparative assessment of multiple COVID-19 serological technologies supports continued evaluation of point-of-care lateral flow assays in hospital and community healthcare settings

scientific article published on 24 September 2020

Complete epitopes for vaccine design derived from a crystal structure of the broadly neutralizing antibodies PGT128 and 8ANC195 in complex with an HIV-1 Env trimer

artículo científico publicado en 2015

Comprehensive antigenic map of a cleaved soluble HIV-1 envelope trimer

artículo científico publicado en 2015

Conformational Plasticity in the HIV-1 Fusion Peptide Facilitates Recognition by Broadly Neutralizing Antibodies

scientific article published on 01 June 2019

Cross-neutralization of a SARS-CoV-2 antibody to a functionally conserved site is mediated by avidity

scientific article published on 03 August 2020

Cryo-EM Structure of a Fully Glycosylated Soluble Cleaved HIV-1 Envelope Trimer

artículo científico publicado en 2013

Crystal Structure of a Soluble Cleaved HIV-1 Envelope Trimer

artículo científico publicado en 2013

Cytokine-Independent Detection of Antigen-Specific Germinal Center T Follicular Helper Cells in Immunized Nonhuman Primates Using a Live Cell Activation-Induced Marker Technique

artículo científico publicado en 2016

Dendritic cell type-specific HIV-1 activation in effector T cells: implications for latent HIV-1 reservoir establishment

artículo científico publicado en 2015

Dendritic cell-induced activation of latent HIV-1 provirus in actively proliferating primary T lymphocytes

artículo científico publicado en 2013

Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo.

artículo científico publicado en 2017

Design and structure of two HIV-1 clade C SOSIP.664 trimers that increase the arsenal of native-like Env immunogens

artículo científico publicado en 2015

Detailed mechanistic insights into HIV-1 sensitivity to three generations of fusion inhibitors

artículo científico publicado en 2009

Developability Assessment of Physicochemical Properties and Stability Profiles of HIV-1 BG505 SOSIP.664 and BG505 SOSIP.v4.1-GT1.1 gp140 Envelope Glycoprotein Trimers as Candidate Vaccine Antigens

scientific article published on 15 February 2019

Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies

artículo científico publicado en 2014

Differential binding of neutralizing and non-neutralizing antibodies to native-like soluble HIV-1 Env trimers, uncleaved Env proteins, and monomeric subunits

artículo científico publicado en 2014

Differential transmission of human immunodeficiency virus type 1 by distinct subsets of effector dendritic cells

artículo científico publicado en 2002

Direct Probing of Germinal Center Responses Reveals Immunological Features and Bottlenecks for Neutralizing Antibody Responses to HIV Env Trimer

artículo científico publicado en 2016

Diverse HIV-1 escape pathways from broadly neutralizing antibody PGDM1400 in humanized mice

artículo científico publicado en 2020

Early development of broadly reactive HIV-1 neutralizing activity in elite neutralizers.

artículo científico publicado en 2014

Effects of sequence changes in the HIV-1 gp41 fusion peptide on CCR5 inhibitor resistance

artículo científico publicado en 2012

Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches

artículo científico publicado en 2017

Emergence of a drug-dependent human immunodeficiency virus type 1 variant during therapy with the T20 fusion inhibitor.

artículo científico publicado en 2004

Engineering and Characterization of a Fluorescent Native-Like HIV-1 Envelope Glycoprotein Trimer.

artículo científico publicado en 2015

Enhanced immunogenicity of HIV-1 envelope gp140 proteins fused to APRIL.

artículo científico publicado en 2014

Enhancing and shaping the immunogenicity of native-like HIV-1 envelope trimers with a two-component protein nanoparticle

scientific article published on 19 September 2019

Enhancing the proteolytic maturation of human immunodeficiency virus type 1 envelope glycoproteins

artículo científico publicado en 2002

Env Exceptionalism: Why Are HIV-1 Env Glycoproteins Atypical Immunogens?

scientific article published on 01 April 2020

Enzymatic removal of mannose moieties can increase the immune response to HIV-1 gp120 in vivo

artículo científico publicado en 2009

Epitopes for neutralizing antibodies induced by HIV-1 envelope glycoprotein BG505 SOSIP trimers in rabbits and macaques.

artículo científico publicado en 2018

Evaluating the immunogenicity of a disulfide-stabilized, cleaved, trimeric form of the envelope glycoprotein complex of human immunodeficiency virus type 1

artículo científico publicado en 2005

Evolution of AZT resistance in HIV-1: the 41-70 intermediate that is not observed in vivo has a replication defect.

artículo científico publicado en 2001

Evolution of the HIV-1 envelope glycoproteins with a disulfide bond between gp120 and gp41

artículo científico publicado en 2004

Evolution of the human immunodeficiency virus type 1 long terminal repeat promoter by conversion of an NF-kappaB enhancer element into a GABP binding site.

artículo científico publicado en 1999

Evolution rescues folding of human immunodeficiency virus-1 envelope glycoprotein GP120 lacking a conserved disulfide bond

artículo científico publicado en 2008

Evolutionary repair of HIV type 1 gp41 with a kink in the N-terminal helix leads to restoration of the six-helix bundle structure

artículo científico publicado en 2004

Gene therapy as a vaccine for HIV-1.

artículo científico

Glycan-dependent immunogenicity of recombinant soluble trimeric hemagglutinin

artículo científico publicado en 2012

Gp120/CD4 blocking antibodies are frequently elicited in ART-naïve chronically HIV-1 infected individuals

artículo científico publicado en 2015

HIV envelope trimer-elicited autologous neutralizing antibodies bind a region overlapping the N332 glycan supersite

artículo científico publicado en 2020

HIV takes double hit before entry

artículo científico publicado en 2013

HIV's Achilles' Heel

artículo científico publicado en 2016

HIV-1 Envelope Trimer Design and Immunization Strategies To Induce Broadly Neutralizing Antibodies

artículo científico publicado en 2016

HIV-1 Escape from a Peptidic Anchor Inhibitor through Stabilization of the Envelope Glycoprotein Spike

artículo científico publicado en 2016

HIV-1 N-glycan composition governs a balance between dendritic cell-mediated viral transmission and antigen presentation

artículo científico publicado en 2011

HIV-1 VACCINES. HIV-1 neutralizing antibodies induced by native-like envelope trimers

artículo científico publicado en 2015

HIV-1 anchor inhibitors and membrane fusion inhibitors target distinct but overlapping steps in virus entry

article

HIV-1 autologous antibody neutralization associates with mother to child transmission

artículo científico publicado en 2013

HIV-1 envelope characteristics that coincide with the development of cross-reactive neutralizing activity in HIV-1 infected patients.

artículo científico publicado en 2011

HIV-1 envelope glycoprotein characteristics that correlate with the development of cross-reactive neutralizing activity in HIV-1 infected individuals

article

HIV-1 envelope glycoprotein immunogens to induce broadly neutralizing antibodies

artículo científico publicado en 2015

HIV-1 envelope glycoprotein resistance to monoclonal antibody 2G12 is subject-specific and context-dependent in macaques and humans

artículo científico publicado en 2013

HIV-1 envelope glycoprotein signatures that correlate with the development of cross-reactive neutralizing activity.

artículo científico publicado en 2013

HIV-1 envelope trimer has similar binding characteristics for carbohydrate-binding agents as monomeric gp120.

artículo científico publicado en 2013

HIV-1 escapes from N332-directed antibody neutralization in an elite neutralizer by envelope glycoprotein elongation and introduction of unusual disulfide bonds

artículo científico publicado en 2016

HIV-1 evades virus-specific IgG2 and IgA responses by targeting systemic and intestinal B cells via long-range intercellular conduits

scientific article published on 02 August 2009

HIV-1 gp120 impairs the induction of B cell responses by TLR9-activated plasmacytoid dendritic cells

artículo científico publicado en 2012

HIV-1 gp120 impairs the induction of B cell responses by TLR9-activated plasmacytoid dendritic cells

article

HIV-1 gp120 mannoses induce immunosuppressive responses from dendritic cells

artículo científico publicado en 2007

HIV-1-neutralizing antibody induced by simian adenovirus- and poxvirus MVA-vectored BG505 native-like envelope trimers

artículo científico publicado en 2017

HIV: A stamp on the envelope

artículo científico publicado en 2014

Harnessing post-translational modifications for next-generation HIV immunogens

article

High-Throughput Protein Engineering Improves the Antigenicity and Stability of Soluble HIV-1 Envelope Glycoprotein SOSIP Trimers

artículo científico publicado en 2017

Histatin 5-derived peptide with improved fungicidal properties enhances human immunodeficiency virus type 1 replication by promoting viral entry

artículo científico publicado en 2006

Hitting HIV's Harpoon

article

Holes in the Glycan Shield of the Native HIV Envelope Are a Target of Trimer-Elicited Neutralizing Antibodies

artículo científico publicado en 2016

How can HIV-type-1-Env immunogenicity be improved to facilitate antibody-based vaccine development?

artículo científico publicado en 2011

IgG subclass profiles in infected HIV type 1 controllers and chronic progressors and in uninfected recipients of Env vaccines

artículo científico publicado en 2010

Immunization for HIV-1 Broadly Neutralizing Antibodies in Human Ig Knockin Mice

artículo científico publicado en 2015

Immunofocusing and enhancing autologous Tier-2 HIV-1 neutralization by displaying Env trimers on two-component protein nanoparticles

artículo científico publicado en 2021

Immunogenicity in rabbits of SOSIP trimers from clades A, B and C, given individually, sequentially or in combinations

artículo científico publicado en 2018

Immunogenicity of Stabilized HIV-1 Envelope Trimers with Reduced Exposure of Non-neutralizing Epitopes

artículo científico publicado en 2015

Immunosilencing a highly immunogenic protein trimerization domain.

artículo científico publicado en 2015

Improving the Expression and Purification of Soluble, Recombinant Native-Like HIV-1 Envelope Glycoprotein Trimers by Targeted Sequence Changes.

artículo científico publicado en 2017

Improving the Immunogenicity of Native-like HIV-1 Envelope Trimers by Hyperstabilization

artículo científico publicado en 2017

Improving the immunogenicity of HIV-1 envelope trimer vaccines.

artículo científico publicado en 2011

In vivo protection by broadly neutralizing HIV antibodies

artículo científico publicado en 2014

Incomplete Neutralization and Deviation from Sigmoidal Neutralization Curves for HIV Broadly Neutralizing Monoclonal Antibodies

artículo científico publicado en 2015

Inference of the HIV-1 VRC01 Antibody Lineage Unmutated Common Ancestor Reveals Alternative Pathways to Overcome a Key Glycan Barrier

article

Influences on the Design and Purification of Soluble, Recombinant Native-Like HIV-1 Envelope Glycoprotein Trimers

artículo científico publicado en 2015

Influences on trimerization and aggregation of soluble, cleaved HIV-1 SOSIP envelope glycoprotein

artículo científico publicado en 2013

Inhibiting HIV-1 entry with fusion inhibitors

artículo científico publicado en 2003

Inhibition of HIV-1 by Fusion Inhibitors ⬇️

artículo científico publicado el 1 de enero de 2010

Integrity of Glycosylation Processing of a Glycan-Depleted Trimeric HIV-1 Immunogen Targeting Key B-Cell Lineages

artículo científico publicado en 2018

Is there a future for antiviral fusion inhibitors?

artículo científico publicado en 2012

Lack of complex N-glycans on HIV-1 envelope glycoproteins preserves protein conformation and entry function

artículo científico publicado en 2010

Lactoferrin prevents dendritic cell-mediated human immunodeficiency virus type 1 transmission by blocking the DC-SIGN--gp120 interaction

artículo científico publicado en 2005

Lower Broadly Neutralizing Antibody Responses in Female Versus Male HIV-1 Infected Injecting Drug Users. ⬇️

artículo científico publicado en 2019

Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates

scientific article published on 31 August 2020

Molecular strategies to design an escape-proof antiviral therapy

artículo científico publicado en 2011

Mucin 6 in seminal plasma binds DC-SIGN and potently blocks dendritic cell mediated transfer of HIV-1 to CD4(+) T-lymphocytes

artículo científico publicado en 2009

Multiple CCR5 conformations on the cell surface are used differentially by human immunodeficiency viruses resistant or sensitive to CCR5 inhibitors.

artículo científico publicado en 2011

Murine Antibody Responses to Cleaved Soluble HIV-1 Envelope Trimers Are Highly Restricted in Specificity

artículo científico publicado en 2015

Native-like Env trimers as a platform for HIV-1 vaccine design

artículo científico publicado en 2017

Networks of HIV-1 Envelope Glycans Maintain Antibody Epitopes in the Face of Glycan Additions and Deletions

scientific article published on 12 May 2020

Neutralizing Antibody Induction by HIV-1 Envelope Glycoprotein SOSIP Trimers on Iron Oxide Nanoparticles May Be Impaired by Mannose Binding Lectin

artículo científico publicado en 2020

Neutralizing antibody responses induced by HIV-1 envelope glycoprotein SOSIP trimers derived from elite neutralizers

artículo científico publicado en 2020

Occluding the mannose moieties on human immunodeficiency virus type 1 gp120 with griffithsin improves the antibody responses to both proteins in mice.

artículo científico publicado en 2011

Oligomeric and conformational properties of a proteolytically mature, disulfide-stabilized human immunodeficiency virus type 1 gp140 envelope glycoprotein

artículo científico publicado en 2002

Only five of 10 strictly conserved disulfide bonds are essential for folding and eight for function of the HIV-1 envelope glycoprotein

artículo científico publicado en 2008

Opposites attract in bispecific antibody engineering

artículo científico publicado en 2017

Optimization of HIV-1 Envelope DNA Vaccine Candidates within Three Different Animal Models, Guinea Pigs, Rabbits and Cynomolgus Macaques

artículo científico publicado en 2013

Optimization of human immunodeficiency virus type 1 envelope glycoproteins with V1/V2 deleted, using virus evolution

artículo científico publicado en 2008

Optimized Hepatitis C Virus (HCV) E2 Glycoproteins and their Immunogenicity in Combination with MVA-HCV

scientific article published on 05 August 2020

Optimizing cellular immunity against HIV-1 Gag and preventing suppression by HIV-1 gp120.

artículo científico publicado en 2012

P05-05. Enhanced immunogenicity of HIV-1 envelope glycoprotein trimers fused to CD40 ligand.

artículo científico publicado en 2009

P07-10. Natural compounds in bodily fluids which bind DC-SIGN and prevent HIV-1 capture and transfer to CD4 cells.

artículo científico publicado en 2009

Partial enzymatic deglycosylation preserves the structure of cleaved recombinant HIV-1 envelope glycoprotein trimers

artículo científico publicado en 2012

Persistent immunogenicity of integrase defective lentiviral vectors delivering membrane-tethered native-like HIV-1 envelope trimers

artículo científico publicado en 2022

Potent induction of antibody-secreting B cells by human dermal-derived CD14+ dendritic cells triggered by dual TLR ligation

artículo científico publicado en 2012

Potent induction of antibody-secreting B-cells by human dermal-derived CD14+ dendritic cells triggered by dual toll-like receptor ligation

artículo científico publicado en 2012

Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability

artículo científico publicado en 2020

Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability

artículo científico publicado en 2020

Presentation of HIV-1 envelope glycoprotein trimers on diverse nanoparticle platforms

scientific article published on 01 July 2019

Presenting native-like HIV-1 envelope trimers on ferritin nanoparticles improves their immunogenicity

artículo científico publicado en 2015

Probability of N332 glycan occupancy on HIV-1 gp120 modulates sensitivity to broadly neutralizing antibodies

artículo científico publicado en 2016

Protein promiscuity: drug resistance and native functions--HIV-1 case

artículo científico publicado en 2005

Quantitation of HIV-1 DNA with a sensitive TaqMan assay that has broad subtype specificity

artículo científico publicado en 2012

Reactivation of Neutralized HIV-1 by Dendritic Cells Is Dependent on the Epitope Bound by the Antibody

artículo científico publicado en 2015

Recognition and penetration of the HIV-1 Env glycan shield by potent broadly neutralizing antibodies

article

Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex

artículo científico publicado en 2014

Reducing V3 Antigenicity and Immunogenicity on Soluble, Native-Like HIV-1 Env SOSIP Trimers

artículo científico publicado en 2017

Refocussing Antibody Responses by Chemical Modification of Vaccine Antigens

article

Resistance of human immunodeficiency virus type 1 to a third-generation fusion inhibitor requires multiple mutations in gp41 and is accompanied by a dramatic loss of gp41 function

artículo científico

Restriction of HIV-1 Escape by a Highly Broad and Potent Neutralizing Antibody

artículo científico publicado en 2020

Role of complex carbohydrates in human immunodeficiency virus type 1 infection and resistance to antibody neutralization

artículo científico publicado en 2010

Sealing the envelope - the HIV-1 envelope glycoproteins as targets for therapeutics and vaccines

scientific article published on 01 January 2010

Selection of T1249-resistant human immunodeficiency virus type 1 variants

artículo científico publicado en 2008

Selective packaging of cellular miRNAs in HIV-1 particles

artículo científico publicado en 2012

Sequential and Simultaneous Immunization of Rabbits with HIV-1 Envelope Glycoprotein SOSIP.664 Trimers from Clades A, B and C.

artículo científico publicado en 2016

Short Communication: Protective Efficacy of Broadly Neutralizing Antibody PGDM1400 Against HIV-1 Challenge in Humanized Mice

artículo científico publicado en 2018

Short Communication: Virion Aggregation by Neutralizing and Nonneutralizing Antibodies to the HIV-1 Envelope Glycoprotein

artículo científico publicado en 2015

Similarities and differences between native HIV-1 envelope glycoprotein trimers and stabilized soluble trimer mimetics

artículo científico publicado en 2019

Site-Specific Glycosylation of Virion-Derived HIV-1 Env Is Mimicked by a Soluble Trimeric Immunogen

article

Stabilization of the V2 loop improves the presentation of V2 loop-associated broadly neutralizing antibody epitopes on HIV-1 envelope trimers

article

Stabilization of the gp120 V3 loop through hydrophobic interactions reduces the immunodominant V3-directed non-neutralizing response to HIV-1 envelope trimers

artículo científico publicado en 2017

Stabilization of the soluble, cleaved, trimeric form of the envelope glycoprotein complex of human immunodeficiency virus type 1.

artículo científico publicado en 2002

Stabilized HIV-1 Envelope Glycoprotein Trimers Lacking the V1V2 Domain, Obtained by Virus Evolution ⬇️

artículo científico publicado el 8 de septiembre de 2010

Stabilized HIV-1 envelope glycoprotein trimers for vaccine use.

artículo científico publicado en 2017

Stabilizing HIV-1 envelope glycoprotein trimers to induce neutralizing antibodies

article

Stable 293 T and CHO cell lines expressing cleaved, stable HIV-1 envelope glycoprotein trimers for structural and vaccine studies

artículo científico publicado en 2014

Stable HIV-1 envelope glycoprotein immune complexes as vaccine immunogens.

artículo científico publicado en 2011

Structural Constraints Determine the Glycosylation of HIV-1 Envelope Trimers

artículo científico publicado en 2015

Structural and functional evaluation of de novo-designed, two-component nanoparticle carriers for HIV Env trimer immunogens

artículo científico publicado en 2020

Structural and immunologic correlates of chemically stabilized HIV-1 envelope glycoproteins.

artículo científico publicado en 2018

Structural characterization of cleaved, soluble HIV-1 envelope glycoprotein trimers

scientific article published on 03 July 2013

Structural delineation of a quaternary, cleavage-dependent epitope at the gp41-gp120 interface on intact HIV-1 Env trimers

artículo científico publicado en 2014

Structure and immunogenicity of a stabilized HIV-1 envelope trimer based on a group-M consensus sequence

scientific article published on 29 May 2019

Structure and topology around the cleavage site regulate post-translational cleavage of the HIV-1 gp160 signal peptide

artículo científico publicado en 2017

Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120

artículo científico publicado en 2013

Sustained antigen availability during germinal center initiation enhances antibody responses to vaccination

scientific article published on 04 October 2016

Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens

artículo científico publicado en 2020

Targeting B-cell germlines and focusing affinity maturation: the next hurdles in HIV-1-vaccine development?

artículo científico publicado en 2014

Targeting HIV-1 envelope glycoprotein trimers to B cells by using APRIL improves antibody responses

artículo científico publicado en 2011

The Envelope-Based Fusion Antigen GP120C14K Forming Hexamer-Like Structures Triggers T Cell and Neutralizing Antibody Responses Against HIV-1

artículo científico publicado en 2019

The Neutralizing Antibody Response in an Individual with Triple HIV-1 Infection Remains Directed at the First Infecting Subtype

artículo científico publicado en 2016

The carbohydrate at asparagine 386 on HIV-1 gp120 is not essential for protein folding and function but is involved in immune evasion.

artículo científico publicado en 2008

The future of influenza vaccines

scientific article published on 06 October 2009

The mannose-dependent epitope for neutralizing antibody 2G12 on human immunodeficiency virus type 1 glycoprotein gp120.

artículo científico publicado en 2002

The microanatomic segregation of selection by apoptosis in the germinal center

artículo científico publicado en 2017

Three mutations switch H7N9 influenza to human-type receptor specificity.

artículo científico publicado en 2017

Trimeric HIV-1 glycoprotein gp140 immunogens and native HIV-1 envelope glycoproteins display the same closed and open quaternary molecular architectures

artículo científico publicado en 2011

Two HIV-1 variants resistant to small molecule CCR5 inhibitors differ in how they use CCR5 for entry

artículo científico publicado en 2009

V3 determinants of HIV-1 escape from the CCR5 inhibitors Maraviroc and Vicriviroc

artículo científico publicado en 2012

Vaccine Elicitation of High Mannose-Dependent Neutralizing Antibodies against the V3-Glycan Broadly Neutralizing Epitope in Nonhuman Primates

artículo científico publicado en 2017

Vaccine-Induced Protection from Homologous Tier 2 SHIV Challenge in Nonhuman Primates Depends on Serum-Neutralizing Antibody Titers

scholarly article by Matthias G Pauthner et al published 15 January 2019 in Immunity

Variable Domain N-Linked Glycans Acquired During Antigen-Specific Immune Responses Can Contribute to Immunoglobulin G Antibody Stability.

artículo científico publicado en 2018

Variable-loop-deleted variants of the human immunodeficiency virus type 1 envelope glycoprotein can be stabilized by an intermolecular disulfide bond between the gp120 and gp41 subunits

artículo científico publicado en 2000

What Do Chaotrope-Based Avidity Assays for Antibodies to HIV-1 Envelope Glycoproteins Measure?

artículo científico publicado en 2015

[HIV vaccine: how far along are we?]

artículo científico publicado en 2020

cGMP production and analysis of BG505 SOSIP.664, an extensively glycosylated, trimeric HIV-1 envelope glycoprotein vaccine candidate

artículo científico publicado en 2017

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