Lista de obras - Lleó A - Dominio Público Uruguay

A C6orf10/LOC101929163 locus is associated with age of onset in C9orf72 carriers

A comprehensive screening of copy number variability in dementia with Lewy bodies

scientific article published on 24 October 2018

A comprehensive study of the genetic impact of rare variants in SORL1 in European early-onset Alzheimer's disease

artículo científico publicado en 2016

A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer’s disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity

article by Sven J. van der Lee et al published 27 May 2019 in Acta Neuropathologica

APOE ε4 genotype-dependent cerebrospinal fluid proteomic signatures in Alzheimer's disease

artículo científico publicado en 2020

APP-derived peptides reflect neurodegeneration in frontotemporal dementia

artículo científico publicado en 2019

Analysis of C9orf72 repeat expansions in a large international cohort of dementia with Lewy bodies.

artículo científico publicado en 2016

Annexin A5 prevents amyloid-β-induced toxicity in choroid plexus: implication for Alzheimer's disease

artículo científico publicado en 2020

Association of Cerebral Amyloid-β Aggregation With Cognitive Functioning in Persons Without Dementia

artículo científico publicado en 2017

Author Correction: GBA and APOE ε4 associate with sporadic dementia with Lewy bodies in European genome wide association study

artículo científico publicado en 2019

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 01 September 2019

Biphasic cortical macro- and microstructural changes in autosomal dominant Alzheimer's disease

artículo científico publicado en 2020

C-terminal fragments of the amyloid precursor protein in cerebrospinal fluid as potential biomarkers for Alzheimer disease

artículo científico publicado en 2017

C9orf72, AAO and ancestry help discriminating behavioural from language variants in FTLD cohorts

scientific article published on 17 September 2020

Cerebrospinal Fluid Biomarkers for Target Engagement and Efficacy in Clinical Trials for Alzheimer's and Parkinson's Diseases

artículo científico publicado en 2016

Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the World Federation of Societies of Biological Psychiatry

artículo científico publicado en 2017

Cerebrospinal fluid biomarkers in trials for Alzheimer and Parkinson diseases

artículo científico publicado en 2014

Cerebrospinal fluid biomarkers of neurodegeneration, synaptic integrity, and astroglial activation across the clinical Alzheimer's disease spectrum

artículo científico publicado en 2019

Consensus guidelines for lumbar puncture in patients with neurological diseases

artículo científico publicado en 2017

Correction to: A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity

scientific article published on 18 January 2020

DISCOVERY AND VALIDATION OF MULTIMODAL BIOMARKER SIGNATURES RELATING TO ALZHEIMER'S DISEASE PATHOLOGY AND PROGRESSION

scholarly article by Sarah Westwood et al published July 2017 in Alzheimer's and Dementia

Decreased circulating ErbB4 ectodomain fragments as a read-out of impaired signaling function in amyotrophic lateral sclerosis

artículo científico publicado en 2018

Deleterious ABCA7 mutations and transcript rescue mechanisms in early onset Alzheimer's disease

artículo científico publicado en 2017

Dense core vesicle markers in CSF and cortical tissues of patients with Alzheimer's disease

artículo científico publicado en 2021

Detection of amyloid beta peptides in body fluids for the diagnosis of alzheimer's disease: Where do we stand?

artículo científico publicado en 2019

Dickkopf-1 Overexpression in vitro Nominates Candidate Blood Biomarkers Relating to Alzheimer's Disease Pathology

artículo científico publicado en 2020

Discovery and validation of plasma proteomic biomarkers relating to brain amyloid burden by SOMAscan assay

artículo científico publicado en 2019

Down syndrome, Alzheimer disease, and cerebral amyloid angiopathy: The complex triangle of brain amyloidosis

scientific article published on 01 July 2019

Elevated levels of Secreted-Frizzled-Related-Protein 1 contribute to Alzheimer's disease pathogenesis

artículo científico publicado en 2019

Exome sequencing in a consanguineous family clinically diagnosed with early-onset Alzheimer's disease identifies a homozygous CTSF mutation

scientific article published on 04 July 2016

Frontotemporal dementia and its subtypes: a genome-wide association study

artículo científico publicado en 2014

GBA and APOE ε4 associate with sporadic dementia with Lewy bodies in European genome wide association study

artículo científico publicado en 2019

Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease

artículo científico publicado en 2014

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

artículo científico publicado en 2019

Genetic variability in SQSTM1 and risk of early-onset Alzheimer dementia: a European early-onset dementia consortium study

artículo científico publicado en 2015

Genome-wide association study of Alzheimer's disease CSF biomarkers in the EMIF-AD Multimodal Biomarker Discovery dataset

artículo científico publicado en 2020

Improved Cerebrospinal Fluid-Based Discrimination between Alzheimer's Disease Patients and Controls after Correction for Ventricular Volumes

artículo científico publicado en 2017

Inflammatory biomarkers in Alzheimer's disease plasma.

artículo científico publicado en 2019

Longitudinal cerebrospinal fluid biomarker trajectories along the Alzheimer's disease continuum in the BIOMARKAPD study

scientific article published on 06 April 2019

Nanoscale structure of amyloid-β plaques in Alzheimer's disease

scientific article published on 26 March 2019

No supportive evidence for TIA1 gene mutations in a European cohort of ALS-FTD spectrum patients

article

Performance and complications of lumbar puncture in memory clinics: Results of the multicenter lumbar puncture feasibility study

artículo científico publicado en 2015

Plasma phosphorylated TDP-43 levels are elevated in patients with frontotemporal dementia carrying a C9orf72 repeat expansion or a GRN mutation

artículo científico publicado en 2013

Prevalence of amyloid PET positivity in dementia syndromes: a meta-analysis

artículo científico publicado en 2015

Prevalence of amyloid-β pathology in distinct variants of primary progressive aphasia

artículo científico publicado en 2018

Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis

artículo científico publicado en 2015

Prevalence of the apolipoprotein E ε4 allele in amyloid β positive subjects across the spectrum of Alzheimer's disease.

artículo científico publicado en 2018

Primary fatty amides in plasma associated with brain amyloid burden, hippocampal volume, and memory in the European Medical Information Framework for Alzheimer's Disease biomarker discovery cohort

scientific article published on 08 May 2019

Rare Variants in PLD3 Do Not Affect Risk for Early-Onset Alzheimer Disease in a European Consortium Cohort

artículo científico publicado en 2015

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

artículo científico publicado en 2017

Rare mutations in SQSTM1 modify susceptibility to frontotemporal lobar degeneration

artículo científico publicado en 2014

Rare nonsynonymous variants in SORT1 are associated with increased risk for frontotemporal dementia.

artículo científico publicado en 2018

Reduced Slow-Wave Sleep Is Associated with High Cerebrospinal Fluid Aβ42 Levels in Cognitively Normal Elderly.

artículo científico publicado en 2016

TBK1 Mutation Spectrum in an Extended European Patient Cohort with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis

scientific article published on 23 December 2016

TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis

artículo científico publicado en 2014

The Central Biobank and Virtual Biobank of BIOMARKAPD: A Resource for Studies on Neurodegenerative Diseases

artículo científico publicado en 2015

The EMIF-AD Multimodal Biomarker Discovery study: design, methods and cohort characteristics.

artículo científico publicado en 2018

The frequency and influence of dementia risk factors in prodromal Alzheimer's disease

artículo científico publicado en 2017

The use of biomarkers for the etiologic diagnosis of MCI in Europe: an EADC survey

artículo científico publicado en 2014

Validation of Plasma Proteomic Biomarkers Relating to Brain Amyloid Burden in the EMIF-Alzheimer's Disease Multimodal Biomarker Discovery Cohort

scientific article published on 01 January 2020

Validation of a quantitative cerebrospinal fluid alpha-synuclein assay in a European-wide interlaboratory study

artículo científico publicado en 2015

White paper by the Society for CSF Analysis and Clinical Neurochemistry: Overcoming barriers in biomarker development and clinical translation.

artículo científico publicado en 2018

sTREM2 cerebrospinal fluid levels are a potential biomarker for microglia activity in early-stage Alzheimer's disease and associate with neuronal injury markers

artículo científico publicado en 2016

Lista de obras de Lleó A

A C6orf10/LOC101929163 locus is associated with age of onset in C9orf72 carriers

A comprehensive screening of copy number variability in dementia with Lewy bodies

A comprehensive study of the genetic impact of rare variants in SORL1 in European early-onset Alzheimer's disease

A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer’s disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity

APOE ε4 genotype-dependent cerebrospinal fluid proteomic signatures in Alzheimer's disease

APP-derived peptides reflect neurodegeneration in frontotemporal dementia

Analysis of C9orf72 repeat expansions in a large international cohort of dementia with Lewy bodies.

Annexin A5 prevents amyloid-β-induced toxicity in choroid plexus: implication for Alzheimer's disease

Association of Cerebral Amyloid-β Aggregation With Cognitive Functioning in Persons Without Dementia

Author Correction: GBA and APOE ε4 associate with sporadic dementia with Lewy bodies in European genome wide association study

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Biphasic cortical macro- and microstructural changes in autosomal dominant Alzheimer's disease

C-terminal fragments of the amyloid precursor protein in cerebrospinal fluid as potential biomarkers for Alzheimer disease

C9orf72, AAO and ancestry help discriminating behavioural from language variants in FTLD cohorts

Cerebrospinal Fluid Biomarkers for Target Engagement and Efficacy in Clinical Trials for Alzheimer's and Parkinson's Diseases

Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the World Federation of Societies of Biological Psychiatry

Cerebrospinal fluid biomarkers in trials for Alzheimer and Parkinson diseases

Cerebrospinal fluid biomarkers of neurodegeneration, synaptic integrity, and astroglial activation across the clinical Alzheimer's disease spectrum

Consensus guidelines for lumbar puncture in patients with neurological diseases

Correction to: A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity

DISCOVERY AND VALIDATION OF MULTIMODAL BIOMARKER SIGNATURES RELATING TO ALZHEIMER'S DISEASE PATHOLOGY AND PROGRESSION

Decreased circulating ErbB4 ectodomain fragments as a read-out of impaired signaling function in amyotrophic lateral sclerosis

Deleterious ABCA7 mutations and transcript rescue mechanisms in early onset Alzheimer's disease

Dense core vesicle markers in CSF and cortical tissues of patients with Alzheimer's disease

Detection of amyloid beta peptides in body fluids for the diagnosis of alzheimer's disease: Where do we stand?

Dickkopf-1 Overexpression in vitro Nominates Candidate Blood Biomarkers Relating to Alzheimer's Disease Pathology

Discovery and validation of plasma proteomic biomarkers relating to brain amyloid burden by SOMAscan assay

Down syndrome, Alzheimer disease, and cerebral amyloid angiopathy: The complex triangle of brain amyloidosis

Elevated levels of Secreted-Frizzled-Related-Protein 1 contribute to Alzheimer's disease pathogenesis

Exome sequencing in a consanguineous family clinically diagnosed with early-onset Alzheimer's disease identifies a homozygous CTSF mutation

Frontotemporal dementia and its subtypes: a genome-wide association study

GBA and APOE ε4 associate with sporadic dementia with Lewy bodies in European genome wide association study

Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Genetic variability in SQSTM1 and risk of early-onset Alzheimer dementia: a European early-onset dementia consortium study

Genome-wide association study of Alzheimer's disease CSF biomarkers in the EMIF-AD Multimodal Biomarker Discovery dataset

Improved Cerebrospinal Fluid-Based Discrimination between Alzheimer's Disease Patients and Controls after Correction for Ventricular Volumes

Inflammatory biomarkers in Alzheimer's disease plasma.

Longitudinal cerebrospinal fluid biomarker trajectories along the Alzheimer's disease continuum in the BIOMARKAPD study

Nanoscale structure of amyloid-β plaques in Alzheimer's disease

No supportive evidence for TIA1 gene mutations in a European cohort of ALS-FTD spectrum patients

Performance and complications of lumbar puncture in memory clinics: Results of the multicenter lumbar puncture feasibility study

Plasma phosphorylated TDP-43 levels are elevated in patients with frontotemporal dementia carrying a C9orf72 repeat expansion or a GRN mutation

Prevalence of amyloid PET positivity in dementia syndromes: a meta-analysis

Prevalence of amyloid-β pathology in distinct variants of primary progressive aphasia

Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis

Prevalence of the apolipoprotein E ε4 allele in amyloid β positive subjects across the spectrum of Alzheimer's disease.

Primary fatty amides in plasma associated with brain amyloid burden, hippocampal volume, and memory in the European Medical Information Framework for Alzheimer's Disease biomarker discovery cohort

Rare Variants in PLD3 Do Not Affect Risk for Early-Onset Alzheimer Disease in a European Consortium Cohort

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

Rare mutations in SQSTM1 modify susceptibility to frontotemporal lobar degeneration

Rare nonsynonymous variants in SORT1 are associated with increased risk for frontotemporal dementia.

Reduced Slow-Wave Sleep Is Associated with High Cerebrospinal Fluid Aβ42 Levels in Cognitively Normal Elderly.

TBK1 Mutation Spectrum in an Extended European Patient Cohort with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis

TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis

The Central Biobank and Virtual Biobank of BIOMARKAPD: A Resource for Studies on Neurodegenerative Diseases

The EMIF-AD Multimodal Biomarker Discovery study: design, methods and cohort characteristics.

The frequency and influence of dementia risk factors in prodromal Alzheimer's disease

The use of biomarkers for the etiologic diagnosis of MCI in Europe: an EADC survey

Validation of Plasma Proteomic Biomarkers Relating to Brain Amyloid Burden in the EMIF-Alzheimer's Disease Multimodal Biomarker Discovery Cohort

Validation of a quantitative cerebrospinal fluid alpha-synuclein assay in a European-wide interlaboratory study

White paper by the Society for CSF Analysis and Clinical Neurochemistry: Overcoming barriers in biomarker development and clinical translation.

sTREM2 cerebrospinal fluid levels are a potential biomarker for microglia activity in early-stage Alzheimer's disease and associate with neuronal injury markers