Lista de obras - Zhenyu Yue - Dominio Público Uruguay

A Role for Autophagic Protein Beclin 1 Early in Lymphocyte Development ⬇️

artículo científico publicado el 14 de enero de 2011

A novel protein complex linking the delta 2 glutamate receptor and autophagy: implications for neurodegeneration in lurcher mice

artículo científico publicado en 2002

ALS-FTLD-linked mutations of SQSTM1/p62 disrupt selective autophagy and NFE2L2/NRF2 anti-oxidative stress pathway

scientific article published on 30 July 2019

Assessment of chloroquine treatment for modulating autophagy flux in brain of WT and HD mice

artículo científico publicado en 2014

Atg14L and Rubicon: yin and yang of Beclin 1-mediated autophagy control

artículo científico publicado en 2009

Autophagy Receptors and Neurodegenerative Diseases

artículo científico publicado en 2017

Autophagy and its normal and pathogenic states in the brain

artículo científico

Autophagy in axonal and dendritic degeneration ⬇️

artículo científico publicado el 30 de abril de 2013

Autophagy in ischemic stroke

artículo científico publicado en 2018

Autophagy in neurodegenerative diseases

artículo científico publicado en 2016

Autophagy is a gatekeeper of hepatic differentiation and carcinogenesis by controlling the degradation of Yap

artículo científico publicado en 2018

Autophagy is induced upon platelet activation and is essential for hemostasis and thrombosis.

artículo científico publicado en 2015

Autophagy modulator scoring system: a user-friendly tool for quantitative analysis of methodological integrity of chemical autophagy modulator studies

artículo científico publicado en 2019

Autophagy of the Nervous System

article published in 2011

Autophagy protein NRBF2 has reduced expression in Alzheimer's brains and modulates memory and amyloid-beta homeostasis in mice

scientific article published on 27 November 2019

Autophagy releases lipid that promotes fibrogenesis by activated hepatic stellate cells in mice and in human tissues.

artículo científico publicado en 2012

B1 is involved in autophagy inhibition caused by SNCA/a-synuclein overexpression: a process modulated by the natural autophagy inducer corynoxine B.

artículo científico publicado en 2015

Beclin 1 is required for neuron viability and regulates endosome pathways via the UVRAG-VPS34 complex

artículo científico publicado en 2014

Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

artículo científico publicado en 2003

CSF-1 controls cerebellar microglia and is required for motor function and social interaction

scientific article published on 26 July 2019

Cell "self-eating" (autophagy) mechanism in Alzheimer's disease

artículo científico publicado en 2010

Correction: Phosphorylation-Dependent 14-3-3 Binding to LRRK2 Is Impaired by Common Mutations of Familial Parkinson's Disease.

artículo científico publicado en 2011

Deregulation of autophagy and vesicle trafficking in Parkinson's disease

scientific article published on 05 April 2018

Diminished autophagy limits cardiac injury in mouse models of type 1 diabetes

artículo científico publicado en 2013

Disentangling the Molecular Pathways of Parkinson's Disease using Multiscale Network Modeling

artículo científico publicado en 2020

Disrupted autophagy leads to dopaminergic axon and dendrite degeneration and promotes presynaptic accumulation of α-synuclein and LRRK2 in the brain

artículo científico publicado en 2012

Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex

artículo científico publicado en 2009

Enhancing depression mechanisms in midbrain dopamine neurons achieves homeostatic resilience

artículo científico publicado en 2014

Essential role for autophagy protein Atg7 in the maintenance of axonal homeostasis and the prevention of axonal degeneration

scientific journal article

Functional variants in the LRRK2 gene confer shared effects on risk for Crohn's disease and Parkinson's disease

artículo científico publicado en 2018

Gammaherpesvirus 68 Infection of Endothelial Cells Requires both Host Autophagy Genes and Viral Oncogenes for Optimal Survival and Persistence ⬇️

artículo científico publicado el 13 de abril de 2011

Guidelines for the use and interpretation of assays for monitoring autophagy

artículo científico publicado en 2012

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

artículo científico publicado en 2008

HMGB1 is involved in autophagy inhibition caused by SNCA/α-synuclein overexpression: a process modulated by the natural autophagy inducer corynoxine B.

artículo científico publicado en 2013

Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice

artículo científico publicado en 2007

Identification of breast cancer candidate genes using gene co-expression and protein-protein interaction information

scientific article published on 02 May 2016

Impaired autophagy in neurons after disinhibition of mammalian target of rapamycin and its contribution to epileptogenesis

artículo científico publicado en 2012

Imperfect interface of Beclin1 coiled-coil domain regulates homodimer and heterodimer formation with Atg14L and UVRAG

artículo científico publicado en 2012

Induction of autophagy in axonal dystrophy and degeneration

scientific journal article

Is amyotrophic lateral sclerosis/frontotemporal dementia an autophagy disease?

artículo científico publicado en 2017

Latrepirdine (dimebon) enhances autophagy and reduces intracellular GFP-Aβ42 levels in yeast.

artículo científico publicado en 2012

Leucine-rich repeat kinase 2 (LRRK2)/PARK8 possesses GTPase activity that is altered in familial Parkinson's disease R1441C/G mutants

artículo científico publicado en 2007

Loss of mTOR-Dependent Macroautophagy Causes Autistic-like Synaptic Pruning Deficits

scholarly article by Guomei Tang et al published September 2014 in Neuron

Loss of mTOR-dependent macroautophagy causes autistic-like synaptic pruning deficits

artículo científico publicado en 2014

Low-variance RNAs identify Parkinson's disease molecular signature in blood

artículo científico publicado en 2015

MTORC1-mediated NRBF2 phosphorylation functions as a switch for the class III PtdIns3K and autophagy

artículo científico publicado en 2017

Molecular definitions of autophagy and related processes.

artículo científico publicado en 2017

NRBF2 is a RAB7 effector required for autophagosome maturation and mediates the association of APP-CTFs with active form of RAB7 for degradation

artículo científico publicado en 2020

NRBF2 is involved in the autophagic degradation process of APP-CTFs in Alzheimer disease models.

artículo científico publicado en 2017

NRBF2 regulates autophagy and prevents liver injury by modulating Atg14L-linked phosphatidylinositol-3 kinase III activity

artículo científico publicado en 2014

Neuronal autophagy: going the distance to the axon.

artículo científico publicado en 2007

Neuronal vulnerability in Parkinson disease: Should the focus be on axons and synaptic terminals?

artículo científico publicado en 2019

Nigericin-induced impairment of autophagic flux in neuronal cells is inhibited by overexpression of Bak.

artículo científico publicado en 2012

PI3KC3 complex subunit NRBF2 is required for apoptotic cell clearance to restrict intestinal inflammation

artículo científico publicado en 2020

Phosphorylation-dependent 14-3-3 binding to LRRK2 is impaired by common mutations of familial Parkinson's disease

scientific journal article

Progress in LRRK2-Associated Parkinson's Disease Animal Models

scientific article published on 15 July 2020

Proteotoxic stress induces phosphorylation of p62/SQSTM1 by ULK1 to regulate selective autophagic clearance of protein aggregates

artículo científico publicado en 2015

Selective association of neurogranin gene expression with amyloid and tau pathology in the parahippocampal gyrus in Alzheimer’s disease

artículo científico publicado en 2020

Short- and long-term effects of LRRK2 on axon and dendrite growth

artículo científico publicado en 2013

Structural model of the dimeric Parkinson's protein LRRK2 reveals a compact architecture involving distant interdomain contacts

scientific journal article

Synaptotagmin-11 is a critical mediator of parkin-linked neurotoxicity and Parkinson's disease-like pathology

artículo científico publicado en 2018

Synj1 Haploinsufficiency Causes Dopamine Neuron Vulnerability and alpha-synuclein Accumulation in Mice

artículo científico publicado en 2020

Targeting the potent Beclin 1-UVRAG coiled-coil interaction with designed peptides enhances autophagy and endolysosomal trafficking.

artículo científico publicado en 2018

Tau accumulation impairs mitophagy via increasing mitochondrial membrane potential and reducing mitochondrial Parkin

artículo científico publicado en 2016

The BECN1 coiled coil domain: an "imperfect" homodimer interface that facilitates ATG14 and UVRAG binding

artículo científico publicado en 2012

The Beclin 1-VPS34 complex--at the crossroads of autophagy and beyond

artículo científico publicado en 2010

The P2RY12 receptor promotes VSMC-derived foam cell formation by inhibiting autophagy in advanced atherosclerosis

scientific article published on 19 March 2020

The Parkinson's Disease-Associated Mutation LRRK2-G2019S Impairs Synaptic Plasticity in Mouse Hippocampus

artículo científico publicado en 2015

The cellular pathways of neuronal autophagy and their implication in neurodegenerative diseases

artículo científico publicado en 2009

The class IA phosphatidylinositol 3-kinase p110-β subunit is a positive regulator of autophagy ⬇️

artículo científico publicado el 8 de noviembre de 2010

The landscape of multiscale transcriptomic networks and key regulators in Parkinson's disease

scientific article published on 20 November 2019

The role of genetics in Parkinson's disease: a large cohort study in Chinese mainland population

artículo científico publicado en 2020

Transformative Network Modeling of Multi-omics Data Reveals Detailed Circuits, Key Regulators, and Potential Therapeutics for Alzheimer's Disease

scientific article published on 17 November 2020

ULK1-mediated phosphorylation of ATG14 promotes autophagy and is impaired in Huntington's disease models

artículo científico publicado en 2016

Using genetic mouse models to study the biology and pathology of autophagy in the central nervous system.

artículo científico publicado en 2009

Vitamin B12 modulates Parkinson's disease LRRK2 kinase activity through allosteric regulation and confers neuroprotection

scientific article published on 11 March 2019

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

artículo científico publicado en 2016

Guía para el uso y la interpretación de ensayos para el seguimiento de la autofagia (4ª edición)

artículo científico

Lista de obras de Zhenyu Yue

A Role for Autophagic Protein Beclin 1 Early in Lymphocyte Development ⬇️

A novel protein complex linking the delta 2 glutamate receptor and autophagy: implications for neurodegeneration in lurcher mice

ALS-FTLD-linked mutations of SQSTM1/p62 disrupt selective autophagy and NFE2L2/NRF2 anti-oxidative stress pathway

Assessment of chloroquine treatment for modulating autophagy flux in brain of WT and HD mice

Atg14L and Rubicon: yin and yang of Beclin 1-mediated autophagy control

Autophagy Receptors and Neurodegenerative Diseases

Autophagy and its normal and pathogenic states in the brain

Autophagy in axonal and dendritic degeneration ⬇️

Autophagy in ischemic stroke

Autophagy in neurodegenerative diseases

Autophagy is a gatekeeper of hepatic differentiation and carcinogenesis by controlling the degradation of Yap

Autophagy is induced upon platelet activation and is essential for hemostasis and thrombosis.

Autophagy modulator scoring system: a user-friendly tool for quantitative analysis of methodological integrity of chemical autophagy modulator studies

Autophagy of the Nervous System

Autophagy protein NRBF2 has reduced expression in Alzheimer's brains and modulates memory and amyloid-beta homeostasis in mice

Autophagy releases lipid that promotes fibrogenesis by activated hepatic stellate cells in mice and in human tissues.

B1 is involved in autophagy inhibition caused by SNCA/a-synuclein overexpression: a process modulated by the natural autophagy inducer corynoxine B.

Beclin 1 is required for neuron viability and regulates endosome pathways via the UVRAG-VPS34 complex

Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

CSF-1 controls cerebellar microglia and is required for motor function and social interaction

Cell "self-eating" (autophagy) mechanism in Alzheimer's disease

Correction: Phosphorylation-Dependent 14-3-3 Binding to LRRK2 Is Impaired by Common Mutations of Familial Parkinson's Disease.

Deregulation of autophagy and vesicle trafficking in Parkinson's disease

Diminished autophagy limits cardiac injury in mouse models of type 1 diabetes

Disentangling the Molecular Pathways of Parkinson's Disease using Multiscale Network Modeling

Disrupted autophagy leads to dopaminergic axon and dendrite degeneration and promotes presynaptic accumulation of α-synuclein and LRRK2 in the brain

Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex

Enhancing depression mechanisms in midbrain dopamine neurons achieves homeostatic resilience

Essential role for autophagy protein Atg7 in the maintenance of axonal homeostasis and the prevention of axonal degeneration

Functional variants in the LRRK2 gene confer shared effects on risk for Crohn's disease and Parkinson's disease

Gammaherpesvirus 68 Infection of Endothelial Cells Requires both Host Autophagy Genes and Viral Oncogenes for Optimal Survival and Persistence ⬇️

Guidelines for the use and interpretation of assays for monitoring autophagy

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

HMGB1 is involved in autophagy inhibition caused by SNCA/α-synuclein overexpression: a process modulated by the natural autophagy inducer corynoxine B.

Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice

Identification of breast cancer candidate genes using gene co-expression and protein-protein interaction information

Impaired autophagy in neurons after disinhibition of mammalian target of rapamycin and its contribution to epileptogenesis

Imperfect interface of Beclin1 coiled-coil domain regulates homodimer and heterodimer formation with Atg14L and UVRAG

Induction of autophagy in axonal dystrophy and degeneration

Is amyotrophic lateral sclerosis/frontotemporal dementia an autophagy disease?

Latrepirdine (dimebon) enhances autophagy and reduces intracellular GFP-Aβ42 levels in yeast.

Leucine-rich repeat kinase 2 (LRRK2)/PARK8 possesses GTPase activity that is altered in familial Parkinson's disease R1441C/G mutants

Loss of mTOR-Dependent Macroautophagy Causes Autistic-like Synaptic Pruning Deficits

Loss of mTOR-dependent macroautophagy causes autistic-like synaptic pruning deficits

Low-variance RNAs identify Parkinson's disease molecular signature in blood

MTORC1-mediated NRBF2 phosphorylation functions as a switch for the class III PtdIns3K and autophagy

Molecular definitions of autophagy and related processes.

NRBF2 is a RAB7 effector required for autophagosome maturation and mediates the association of APP-CTFs with active form of RAB7 for degradation

NRBF2 is involved in the autophagic degradation process of APP-CTFs in Alzheimer disease models.

NRBF2 regulates autophagy and prevents liver injury by modulating Atg14L-linked phosphatidylinositol-3 kinase III activity

Neuronal autophagy: going the distance to the axon.

Neuronal vulnerability in Parkinson disease: Should the focus be on axons and synaptic terminals?

Nigericin-induced impairment of autophagic flux in neuronal cells is inhibited by overexpression of Bak.

PI3KC3 complex subunit NRBF2 is required for apoptotic cell clearance to restrict intestinal inflammation

Phosphorylation-dependent 14-3-3 binding to LRRK2 is impaired by common mutations of familial Parkinson's disease

Progress in LRRK2-Associated Parkinson's Disease Animal Models

Proteotoxic stress induces phosphorylation of p62/SQSTM1 by ULK1 to regulate selective autophagic clearance of protein aggregates

Selective association of neurogranin gene expression with amyloid and tau pathology in the parahippocampal gyrus in Alzheimer’s disease

Short- and long-term effects of LRRK2 on axon and dendrite growth

Structural model of the dimeric Parkinson's protein LRRK2 reveals a compact architecture involving distant interdomain contacts

Synaptotagmin-11 is a critical mediator of parkin-linked neurotoxicity and Parkinson's disease-like pathology

Synj1 Haploinsufficiency Causes Dopamine Neuron Vulnerability and alpha-synuclein Accumulation in Mice

Targeting the potent Beclin 1-UVRAG coiled-coil interaction with designed peptides enhances autophagy and endolysosomal trafficking.

Tau accumulation impairs mitophagy via increasing mitochondrial membrane potential and reducing mitochondrial Parkin

The BECN1 coiled coil domain: an "imperfect" homodimer interface that facilitates ATG14 and UVRAG binding

The Beclin 1-VPS34 complex--at the crossroads of autophagy and beyond

The P2RY12 receptor promotes VSMC-derived foam cell formation by inhibiting autophagy in advanced atherosclerosis

The Parkinson's Disease-Associated Mutation LRRK2-G2019S Impairs Synaptic Plasticity in Mouse Hippocampus

The cellular pathways of neuronal autophagy and their implication in neurodegenerative diseases

The class IA phosphatidylinositol 3-kinase p110-β subunit is a positive regulator of autophagy ⬇️

The landscape of multiscale transcriptomic networks and key regulators in Parkinson's disease

The role of genetics in Parkinson's disease: a large cohort study in Chinese mainland population

Transformative Network Modeling of Multi-omics Data Reveals Detailed Circuits, Key Regulators, and Potential Therapeutics for Alzheimer's Disease

ULK1-mediated phosphorylation of ATG14 promotes autophagy and is impaired in Huntington's disease models

Using genetic mouse models to study the biology and pathology of autophagy in the central nervous system.

Vitamin B12 modulates Parkinson's disease LRRK2 kinase activity through allosteric regulation and confers neuroprotection

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Guía para el uso y la interpretación de ensayos para el seguimiento de la autofagia (4ª edición)