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Lista de obras de Malcolm Macleod

A (mini) pill for stroke?

A European initiative to unclog pipeline for new medicines

artículo científico publicado en 2019

A call for transparent reporting to optimize the predictive value of preclinical research

artículo científico publicado en 2012

A concerted appeal for international cooperation in preclinical stroke research

artículo científico publicado en 2013

A proposed framework for the systematic review and integrated assessment (SYRINA) of endocrine disrupting chemicals ⬇️

artículo científico publicado en 2016

A randomised controlled trial of an Intervention to Improve Compliance with the ARRIVE guidelines (IICARus)

A randomised controlled trial of an Intervention to Improve Compliance with the ARRIVE guidelines (IICARus).

artículo científico publicado en 2019

A systematic review and meta-analysis of erythropoietin in experimental stroke

artículo científico publicado en 2009

A systematic review and meta-analysis of gene therapy in animal models of cerebral glioma: why did promise not translate to human therapy?

artículo científico publicado en 2014

A systematic review and meta-analysis of the efficacy of piracetam and piracetam-like compounds in experimental stroke

artículo científico publicado en 2007

A systematic review and meta-analysis of topoisomerase inhibition in pre-clinical glioma models.

artículo científico publicado en 2018

Administration of galacto-oligosaccharide prebiotics in the Flinders Sensitive Line animal model of depression

Alpha Calcitonin Gene-Related Peptide Increases Cerebral Vessel Diameter in Animal Models of Subarachnoid Hemorrhage: A Systematic Review and Meta-analysis.

artículo científico

Animal models of bone cancer pain: systematic review and meta-analyses ⬇️

artículo científico publicado en 2013

Animal models of chemotherapy-induced peripheral neuropathy: A machine-assisted systematic review and meta-analysis

artículo científico publicado en 2019

Animal models of neurological disease: are there any babies in the bathwater?

artículo científico publicado en 2010

Aortic arch atheroma

artículo científico publicado en 2006

Atheroma of the aortic arch: an important and poorly recognised factor in the aetiology of stroke

artículo científico publicado en 2004

Atheroma of the aortic arch: the missing link in the secondary prevention of stroke?

artículo científico publicado en 2003

Bacterial meningitis associated with a complex ischiorectal abscess

Biomedical research: increasing value, reducing waste

artículo científico publicado en 2014

Bringing rigour to translational medicine

artículo científico publicado en 2013

Can animal models of disease reliably inform human studies?

artículo científico publicado en 2010

Can harmonisation of outcomes bridge the translation gap for pre-clinical research? A systematic review of outcomes measured in mouse models of type 2 diabetes

artículo científico publicado en 2020

Cardiac Stem Cell Treatment in Myocardial Infarction: A Systematic Review and Meta-Analysis of Preclinical Studies.

artículo científico publicado en 2016

Caspase 6 activity initiates caspase 3 activation in cerebellar granule cell apoptosis

artículo científico publicado en 2000

Clopidogrel plus aspirin versus warfarin in patients with stroke and aortic arch plaques.

artículo científico

Comment on "Detection of an Infectious Retrovirus, XMRV, in Blood Cells of Patients with Chronic Fatigue Syndrome"

artículo científico publicado en 2010

Comparison of treatment effects between animal experiments and clinical trials: systematic review

artículo científico publicado en 2006

Conjugal amyotrophic lateral sclerosis: a case report from Scotland

artículo científico publicado en 2017

Correction: Risk of Bias in Reports of In Vivo Research: A Focus for Improvement

artículo científico publicado en 2015

Corrigendum to 'Meta-analysis of data from animal studies: A practical guide': [Journal of Neuroscience Methods 221 (2014) 92-102].

artículo científico publicado en 2015

Current issues in the treatment of acute posterior circulation stroke

artículo científico publicado en 2006

D-galactose-induced brain ageing model: A systematic review and meta-analysis on cognitive outcomes and oxidative stress indices

artículo científico publicado en 2017

Design animal studies better

artículo científico publicado en 2014

Development of a psychological intervention for fatigue after stroke.

artículo científico

Different strokes for different folks: the rich diversity of animal models of focal cerebral ischemia

artículo científico publicado en 2010

Dopamine agonists in animal models of Parkinson's disease: a systematic review and meta-analysis

artículo científico publicado en 2011

Drug repurposing: a systematic approach to evaluate candidate oral neuroprotective interventions for secondary progressive multiple sclerosis ⬇️

artículo científico publicado en 2015

EBRNetwork – a call to action for evidence-based research.

artículo científico publicado en 2015

Edaravone improves functional and structural outcomes in animal models of focal cerebral ischemia: a systematic review

artículo científico publicado en 2013

Effect and reporting bias of RhoA/ROCK-blockade intervention on locomotor recovery after spinal cord injury: a systematic review and meta-analysis

artículo científico

Effect of deprivation and gender on the incidence and management of acute brain disorders.

artículo científico publicado en 2002

Effect of deprivation on time to hospital in acute stroke

artículo científico publicado en 2003

Effect of endothelin receptor antagonists on clinically relevant outcomes after experimental subarachnoid hemorrhage: a systematic review and meta-analysis

artículo científico publicado en 2015

Effect of hyperthermia and anoxia on glucocorticoid and mineralocorticoid receptor expression in neonatal rat hippocampus.

artículo científico publicado en 2008

Effect size and statistical power in the rodent fear conditioning literature - A systematic review.

artículo científico publicado en 2018

Effect size and statistical power in the rodent fear conditioning literature - a systematic review

article

Efficacy and safety of mesenchymal stromal cells in preclinical models of acute lung injury: a systematic review protocol.

artículo científico publicado en 2014

Efficacy of antidepressants in animal models of ischemic stroke: a systematic review and meta-analysis

artículo científico

Embrace heterogeneity to improve reproducibility: A perspective from meta-analysis of variation in preclinical research

artículo científico publicado en 2020

Empirical evidence of bias in the design of experimental stroke studies: a metaepidemiologic approach.

artículo científico publicado en 2008

End-of-life decisions in patients with severe acute brain injury

artículo científico publicado en 2014

EuroHYP-1: European multicenter, randomized, phase III clinical trial of therapeutic hypothermia plus best medical treatment vs. best medical treatment alone for acute ischemic stroke

artículo científico

Evaluating mesenchymal stem cell therapy for sepsis with preclinical meta-analyses prior to initiating a first-in-human trial

artículo científico publicado en 2016

Evaluation of combination therapy in animal models of cerebral ischemia

artículo científico publicado en 2012

Evaluation of excess significance bias in animal studies of neurological diseases

artículo científico publicado en 2013

Evidence for the efficacy of NXY-059 in experimental focal cerebral ischaemia is confounded by study quality

artículo científico publicado en 2008

Evidence synthesis in trial design: an example from the neurosciences.

artículo científico publicado en 2013

Evidence-based translational medicine

artículo científico publicado en 2013

Evolution of ischemic damage and behavioural deficit over 6 months after MCAo in the rat: Selecting the optimal outcomes and statistical power for multi-centre preclinical trials

artículo científico publicado en 2017

Exercise reduces infarct volume and facilitates neurobehavioral recovery: results from a systematic review and meta-analysis of exercise in experimental models of focal ischemia.

artículo científico

Experimental design and reporting standards for improving the internal validity of pre-clinical studies in the field of pain: Consensus of the IMI-Europain consortium

artículo científico publicado en 2015

Facilitating healthcare decisions by assessing the certainty in the evidence from preclinical animal studies.

artículo científico publicado en 2018

Factors affecting the apparent efficacy and safety of tissue plasminogen activator in thrombotic occlusion models of stroke: systematic review and meta-analysis

artículo científico publicado en 2010

Failed trials for central nervous system disorders do not necessarily invalidate preclinical models and drug targets

artículo científico publicado en 2016

Findings of a retrospective, controlled cohort study of the impact of a change in Nature journals' editorial policy for life sciences research on the completeness of reporting study design and execution

Forebrain mineralocorticoid receptor overexpression enhances memory, reduces anxiety and attenuates neuronal loss in cerebral ischaemia

artículo científico publicado en 2007

Framework for advancing rigorous research

artículo científico publicado en 2020

Frequency and Phenotype Associations of Rare Variants in 5 Monogenic Cerebral Small Vessel Disease Genes in 200,000 UK Biobank Participants

artículo científico publicado en 2022

Gender and deprivation and rates of referral and thereby admission to a national neurorehabilitation service

artículo científico publicado en 2005

Good laboratory practice: preventing introduction of bias at the bench

artículo científico publicado en 2008

Greater Incidence of Both Fatal and Nonfatal Strokes in Disadvantaged Areas

article

Hemicraniectomy after middle cerebral artery infarction with life-threatening Edema trial (HAMLET). Protocol for a randomised controlled trial of decompressive surgery in space-occupying hemispheric infarction

artículo científico publicado en 2006

How can we improve the pre-clinical development of drugs for stroke?

artículo científico publicado en 2007

Hypertension and experimental stroke therapies

artículo científico publicado en 2013

Hypothermia for Stroke: Call to Action 2010 ⬇️

artículo científico publicado el 1 de diciembre de 2010

Hypothermia in animal models of acute ischaemic stroke: a systematic review and meta-analysis

artículo científico publicado en 2007

Hypothermia protects human neurons.

artículo científico publicado en 2014

Hypothermia revisited: Impact of ischaemic duration and between experiment variability.

artículo científico publicado en 2017

Identification and characterization of outcome measures reported in animal models of epilepsy: Protocol for a systematic review of the literature-A TASK2 report of the AES/ILAE Translational Task Force of the ILAE.

artículo científico publicado en 2017

Identifying stroke therapeutics from preclinical models: A protocol for a novel application of network meta-analysis

artículo científico publicado en 2019

Improving the efficiency of the development of drugs for stroke

artículo científico publicado en 2012

Improving the translational hit of experimental treatments in multiple sclerosis

scientific article published on 04 August 2010

Incidence, prevalence, and predictors of chemotherapy-induced peripheral neuropathy: A systematic review and meta-analysis

artículo científico publicado en 2014

Increasing value and reducing waste in animal models of rheumatological disease

artículo científico publicado en 2015

Increasing value and reducing waste in biomedical research regulation and management

artículo científico publicado en 2014

Increasing value and reducing waste in research design, conduct, and analysis

artículo científico publicado en 2014

Informatics: Make sense of health data

artículo científico publicado en 2015

Injury-induced mineralocorticoid receptor expression involves differential promoter usage: a novel role for the rat MRbeta variant

artículo científico publicado en 2009

Interventions for post-stroke fatigue

artículo científico publicado en 2015

Introducing our series: research synthesis and meta-research in biology

artículo científico publicado en 2020

Introduction to the EQIPD quality system

artículo científico publicado en 2021

Ischaemic heart disease and cholesterol. "Cholesterol papers" add to the confusion...

artículo científico publicado en 1994

Learning lessons from MVA85A, a failed booster vaccine for BCG.

artículo científico publicado en 2018

Machine learning algorithms for systematic review: reducing workload in a preclinical review of animal studies and reducing human screening error

article

Magnetic resonance imaging in experimental stroke and comparison with histology: systematic review and meta-analysis

artículo científico publicado en 2015

Making the most of animal data – improving the prospect of success in pragmatic trials in the neurosciences.

artículo científico publicado en 2011

Meta-analysis of data from animal studies: a practical guide

artículo científico publicado en 2013

Meta-analysis of pre-clinical studies of early decompression in acute spinal cord injury: a battle of time and pressure

artículo científico publicado en 2013

Meta-analysis of variation suggests that embracing variability improves both replicability and generalizability in preclinical research

artículo científico publicado en 2021

Meta-analysis on reporting practices as a source of heterogeneity in in vitro cancer research

artículo científico publicado en 2022

MicroRNA – Taking Regulation of Protein Synthesis to Another Level

Mineralocorticoid receptor expression and increased survival following neuronal injury

artículo científico publicado en 2003

Mineralocorticoid receptor mRNA expression is increased in human hippocampus following brief cerebral ischaemia

artículo científico publicado en 2009

Model of understanding fatigue after stroke

artículo científico

Motor Neuron Disease Systematic Multi-Arm Adaptive Randomised Trial (MND-SMART): a multi-arm, multi-stage, adaptive, platform, phase III randomised, double-blind, placebo-controlled trial of repurposed drugs in motor neuron disease

artículo científico publicado en 2022

Multicenter Evaluation of Geometric Accuracy of MRI Protocols Used in Experimental Stroke

artículo científico publicado en 2016

NXY-059, a Failed Stroke Neuroprotectant, Offers No Protection to Stem Cell-Derived Human Neurons.

artículo científico publicado en 2018

Nitric-oxide-synthase-mediated cyclic guanosine monophosphate production in neonatal rat cerebellar prisms is resistant to calcineurin inhibition

artículo científico publicado en 2002

Not Tonight, Darling, I Might Get a Headache

scholarly article by Malcolm Macleod & Phil M. White published July 2011 in Stroke Journal

Olfactory Ensheathing Cell Transplantation in Experimental Spinal Cord Injury: Effect size and Reporting Bias of 62 Experimental Treatments: A Systematic Review and Meta-Analysis.

artículo científico publicado en 2016

Outcome heterogeneity and bias in acute experimental spinal cord injury: A meta-analysis

scientific article published on 07 June 2019

Overexpression of the mineralocorticoid receptor protects against injury in PC12 cells

artículo científico publicado en 2005

P60WHY ANIMAL MODELS OF GENE THERAPY HAVE LET GLIOMA PATIENTS DOWN.

artículo científico publicado en 2014

PRECIOUS: PREvention of Complications to Improve OUtcome in elderly patients with acute Stroke. Rationale and design of a randomised, open, phase III, clinical trial with blinded outcome assessment

artículo científico publicado en 2018

Pharmacologic reduction of angiographic vasospasm in experimental subarachnoid hemorrhage: systematic review and meta-analysis

artículo científico publicado en 2012

Pooling of animal experimental data reveals influence of study design and publication bias

artículo científico publicado en 2004

Potentially serious incidental findings on brain and body magnetic resonance imaging of apparently asymptomatic adults: systematic review and meta-analysis

scientific article published in the British Medical Journal

Preclinical drug evaluation for combination therapy in acute stroke using systematic review, meta-analysis, and subsequent experimental testing

artículo científico publicado en 2010

Preclinical studies of human disease: time to take methodological quality seriously.

artículo científico publicado en 2011

Prevalence and natural history of pain in adults with multiple sclerosis: systematic review and meta-analysis

artículo científico publicado en 2013

Prof Benchie and Dr Athena-A modern tragedy….

artículo científico publicado en 2015

Protocol for a retrospective, controlled cohort study of the impact of a change in Nature journals' editorial policy for life sciences research on the completeness of reporting study design and execution

artículo científico publicado en 2016

Protocol for a systematic review of guidelines for rigour in the design, conduct and analysis of biomedical experiments involving laboratory animals

Protocol for meta-analysis of temperature reduction in animal models of cardiac arrest

artículo científico publicado en 2016

Psychological associations of poststroke fatigue: a systematic review and meta-analysis

artículo científico publicado en 2014

PubMed: http://www.pubmed.org

artículo científico publicado en 2002

Publication bias in reports of animal stroke studies leads to major overstatement of efficacy

artículo científico publicado en 2010

Reader response: Evaluating depression and suicidality in tetrabenazine users with Huntington disease

Real-world Independent Testing of e-ASPECTS Software (RITeS): statistical analysis plan

artículo científico publicado en 2020

Reduced NMDA-induced apoptosis in neurons lacking ataxia telangiectasia mutated protein

artículo científico publicado en 2003

Reporting animal research: Explanation and elaboration for the ARRIVE guidelines 2.0.

artículo científico publicado en 2020

Reprint: Good laboratory practice: preventing introduction of bias at the bench

artículo científico publicado en 2008

Reprint: Good laboratory practice: preventing introduction of bias at the bench

artículo científico publicado en 2009

Research: increasing value, reducing waste - Authors' reply.

artículo científico publicado en 2014

Results of a multicentre, randomised controlled trial of intra-arterial urokinase in the treatment of acute posterior circulation ischaemic stroke

artículo científico publicado en 2005

Risk of Bias in Reports of In Vivo Research: A Focus for Improvement

artículo científico publicado en 2015

Risk of bias reporting in the recent animal focal cerebral ischaemia literature

artículo científico publicado en 2017

SWIFT-Review: a text-mining workbench for systematic review

artículo científico publicado en 2016

Scope of preclinical testing versus quality control within experiments.

artículo científico publicado en 2009

Serum withdrawal causes apoptosis in SHSY 5Y cells.

artículo científico publicado en 2001

Similar effect of autologous and allogeneic cell therapy for ischemic heart disease: systematic review and meta-analysis of large animal studies

artículo científico

Small vessels, dementia and chronic diseases - molecular mechanisms and pathophysiology. ⬇️

artículo científico publicado en 2018

Sodium and chloride channelopathies with myositis: coincidence or connection?

artículo científico publicado en 2011

Some salt with your statin, professor?

artículo científico publicado en 2014

Standardized mean differences cause funnel plot distortion in publication bias assessments

artículo científico publicado en 2017

Statistical analysis plan for the EuroHYP-1 trial: European multicentre, randomised, phase III clinical trial of the therapeutic hypothermia plus best medical treatment versus best medical treatment alone for acute ischaemic stroke.

artículo científico publicado en 2017

Stem cell transplantation in traumatic spinal cord injury: a systematic review and meta-analysis of animal studies

artículo científico publicado en 2013

Stem cell-based therapy for experimental stroke: a systematic review and meta-analysis.

artículo científico publicado en 2012

Stroke

artículo científico publicado en 2008

Stroke research at a road block: the streets from adversity should be paved with meta-analysis and good laboratory practice

artículo científico publicado en 2009

Study protocol - A systematic review and meta-analysis of hypothermia in experimental traumatic brain injury: Why have promising animal studies not been replicated in pragmatic clinical trials?

artículo científico publicado en 2016

Surveying the literature from animal experiments: systematic review and meta-analysis are important contributions

artículo científico publicado en 2005

Systematic Review and Meta-Analysis of the Efficacy of Interleukin-1 Receptor Antagonist in Animal Models of Stroke: an Update

artículo científico publicado en 2016

Systematic review and meta-analysis of interventions tested in animal models of lacunar stroke.

artículo científico

Systematic review and meta-analysis of temozolomide in animal models of glioma: was clinical efficacy predicted?

artículo científico

Systematic review and meta-analysis of the efficacy of melatonin in experimental stroke

artículo científico publicado en 2005

Systematic review and meta-analysis of the efficacy of tirilazad in experimental stroke

artículo científico publicado en 2007

Systematic review and meta-analysis of therapeutic hypothermia in animal models of spinal cord injury

artículo científico publicado en 2013

Systematic review and metaanalysis of the efficacy of FK506 in experimental stroke

artículo científico publicado en 2005

Systematic review and stratified meta-analysis of the efficacy of RhoA and Rho kinase inhibitors in animal models of ischaemic stroke

artículo científico publicado en 2013

Systematic review and stratified meta-analysis of the efficacy of interleukin-1 receptor antagonist in animal models of stroke

scientific article published on July 2009

Systematic reviews and meta-analysis of preclinical studies: why perform them and how to appraise them critically

artículo científico publicado en 2014

Systematic survey of the design, statistical analysis, and reporting of studies published in the 2008 volume of the Journal of Cerebral Blood Flow and Metabolism ⬇️

artículo científico publicado en 2011

The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research

artículo científico publicado en 2020

The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research

artículo científico publicado en 2020

The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research

artículo científico publicado en 2020

The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research

artículo científico publicado en 2020

The ARRIVE guidelines 2.0: updated guidelines for reporting animal research

scientific article published on 14 July 2020

The ARRIVE guidelines 2.0: updated guidelines for reporting animal research

artículo científico publicado en 2020

The Devil Is in the Details: Incomplete Reporting in Preclinical Animal Research.

artículo científico publicado en 2016

The Efficacy of Trastuzumab in Animal Models of Breast Cancer: A Systematic Review and Meta-Analysis

artículo científico publicado en 2016

The Experimental Design Assistant

artículo científico publicado en 2017

The Experimental Design Assistant

artículo científico publicado en 2017

The IMPROVE Guidelines (Ischaemia Models: Procedural Refinements Of in Vivo Experiments).

artículo científico

The benefit of hypothermia in experimental ischemic stroke is not affected by pethidine

artículo científico publicado en 2012

The development and evaluation of an online application to assist in the extraction of data from graphs for use in systematic reviews

article

The development and evaluation of an online application to assist in the extraction of data from graphs for use in systematic reviews

scholarly article by Fala Cramond et al published 25 January 2019 in Wellcome Open Research

The development of an online database for interventions tested in transgenic mouse models of Alzheimer's disease.

artículo científico publicado en 2015

The effect of tumour associated epilepsy on performance/handicap scales used in cerebral glioma

artículo científico publicado en 1995

The future of restorative neurosciences in stroke: driving the translational research pipeline from basic science to rehabilitation of people after stroke

artículo científico publicado en 2009

The reproducibility opportunity

scientific article published on 01 September 2018

The use of text-mining and machine learning algorithms in systematic reviews: reducing workload in preclinical biomedical sciences and reducing human screening error

scholarly article published 31 January 2018

Therapeutic hypothermia and the risk of infection: a systematic review and meta-analysis

artículo científico publicado en 2014

Therapeutic hypothermia for acute ischaemic stroke. Results of a European multicentre, randomised, phase III clinical trial

artículo científico publicado en 2019

Therapeutic hypothermia for acute ischemic stroke: ready to start large randomized trials?

artículo científico publicado en 2010

Towards minimum reporting standards for life scientists

Translational Research

artículo científico publicado en 2012

Translational failure of anti-inflammatory compounds for myocardial infarction: a meta-analysis of large animal models

artículo científico publicado en 2015

Transparency in the reporting of in vivo pre-clinical pain research: The relevance and implications of the ARRIVE (Animal Research: Reporting In Vivo Experiments) guidelines

artículo científico publicado en 2013

Treatment of intracerebral hemorrhage in animal models: meta-analysis.

artículo científico publicado en 2011

Understanding in vivo modelling of depression in non-human animals: a systematic review protocol

article

Understanding the provenance and quality of methods is essential for responsible reuse of FAIR data

artículo científico publicado en 2024

Using animal models to understand cancer pain in humans

artículo científico

Vanishing diplopia: a problem case

artículo científico publicado en 2007

Voltage-gated potassium channel antibody-related encephalopathy: a case which may extend the documented phenotype of this condition

artículo científico publicado en 2012

What is the translational efficacy of chemotherapeutic drug research in neuro-oncology? A systematic review and meta-analysis of the efficacy of BCNU and CCNU in animal models of glioma.

artículo científico publicado en 2008

What's a good doctor and how do you make one? How not to do it

Why animal research needs to improve.

artículo científico publicado en 2011

Ninguna publicación sin confirmación.

artículo científico publicado en 2017

On the neuroprotective actions of FK506

tesis doctoral

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