Lista de obras - Munn DH - Dominio Público Uruguay

A novel immunohistochemical score to predict early mortality in acute myeloid leukemia patients based on indoleamine 2,3 dioxygenase expression

artículo científico publicado en 2017

Activation of p53 in Immature Myeloid Precursor Cells Controls Differentiation into Ly6c+CD103+ Monocytic Antigen-Presenting Cells in Tumors

artículo científico publicado en 2018

Activation of the STING adaptor attenuates experimental autoimmune encephalitis.

artículo científico publicado en 2014

Activation-induced apoptosis in human macrophages: developmental regulation of a novel cell death pathway by macrophage colony-stimulating factor and interferon gamma.

artículo científico publicado en 1995

Adjuvant IL-7 potentiates adoptive T cell therapy by amplifying and sustaining polyfunctional antitumor CD4+ T cells

artículo científico publicado en 2017

Advanced Age Increases Immunosuppression in the Brain and Decreases Immunotherapeutic Efficacy in Subjects with Glioblastoma

artículo científico publicado en 2020

An inherently bifunctional subset of Foxp3+ T helper cells is controlled by the transcription factor eos.

artículo científico publicado en 2013

Antibody-independent phagocytosis of tumor cells by human monocyte-derived macrophages cultured in recombinant macrophage colony-stimulating factor ⬇️

artículo científico publicado el 1 de julio de 1995

Antigen-specific bacterial vaccine combined with anti-PD-L1 rescues dysfunctional endogenous T cells to reject long-established cancer.

artículo científico publicado en 2013

Aortic endothelial cells regulate proliferation of human monocytes in vitro via a mechanism synergistic with macrophage colony-stimulating factor. Convergence at the cyclin E/p27(Kip1) regulatory checkpoint

artículo científico publicado en 1997

Apoptotic cell-induced AhR activity is required for immunological tolerance and suppression of systemic lupus erythematosus in mice and humans

scientific article published on 14 May 2018

B-lymphoid cells with attributes of dendritic cells regulate T cells via indoleamine 2,3-dioxygenase

artículo científico publicado en 2010

Blockade of programmed death-1 pathway rescues the effector function of tumor-infiltrating T cells and enhances the antitumor efficacy of lentivector immunization.

artículo científico publicado en 2010

Blocking IDO activity to enhance anti-tumor immunity.

artículo científico publicado en 2012

Butyrate suppresses colonic inflammation through HDAC1-dependent Fas upregulation and Fas-mediated apoptosis of T cells.

artículo científico publicado en 2012

CD73 on cancer-associated fibroblasts enhanced by the A2B-mediated feedforward circuit enforces an immune checkpoint

artículo científico publicado en 2020

Canonical wnt signaling in dendritic cells regulates Th1/Th17 responses and suppresses autoimmune neuroinflammation

artículo científico publicado en 2015

Cell-autonomous control of interferon type I expression by indoleamine 2,3-dioxygenase in regulatory CD19+ dendritic cells.

artículo científico publicado en 2007

Cells expressing indoleamine 2,3-dioxygenase inhibit T cell responses.

artículo científico publicado en 2002

Chemo-Immunotherapy: Role of Indoleamine 2,3-Dioxygenase in Defining Immunogenic Versus Tolerogenic Cell Death in the Tumor Microenvironment

artículo científico publicado en 2017

Chronic inflammation that facilitates tumor progression creates local immune suppression by inducing indoleamine 2,3 dioxygenase.

artículo científico publicado en 2008

Creating immune privilege: active local suppression that benefits friends, but protects foes.

artículo científico publicado en 2008

Cutting edge: DNA sensing via the STING adaptor in myeloid dendritic cells induces potent tolerogenic responses

artículo científico publicado en 2013

Cutting edge: induced indoleamine 2,3 dioxygenase expression in dendritic cell subsets suppresses T cell clonal expansion.

artículo científico publicado en 2003

Cytokine regulation of human monocyte differentiation in vitro: the tumor-cytotoxic phenotype induced by macrophage colony-stimulating factor is developmentally regulated by gamma-interferon

scientific article published on 01 June 1993

Danger-associated extracellular ATP counters MDSC therapeutic efficacy in acute GVHD

scientific article published on 01 November 2019

Decreased protein nitration in macrophages that overexpress indoleamine 2, 3-dioxygenase

artículo científico publicado en 2006

Deficient tryptophan catabolism along the kynurenine pathway reveals that the epididymis is in a unique tolerogenic state.

artículo científico publicado en 2010

Deletion of LRP5 and LRP6 in dendritic cells enhances antitumor immunity.

artículo científico publicado en 2015

Dendritic Cell Expression of Retinal Aldehyde Dehydrogenase-2 Controls Graft-versus-Host Disease Lethality

scientific article published on 18 March 2019

Dendritic cells have the option to express IDO-mediated suppression or not

artículo científico publicado en 2005

Donor and host B7-H4 expression negatively regulates acute graft-versus-host disease lethality

scientific article published on 03 October 2019

ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression

artículo científico publicado en 2019

Engineering DNA Nanoparticles as Immunomodulatory Reagents that Activate Regulatory T Cells ⬇️

artículo científico publicado el 18 de abril de 2012

Epitope-optimized alpha-fetoprotein genetic vaccines prevent carcinogen-induced murine autochthonous hepatocellular carcinoma

artículo científico publicado en 2014

Expression of indoleamine 2,3-dioxygenase by plasmacytoid dendritic cells in tumor-draining lymph nodes.

artículo científico publicado en 2004

GCN2 drives macrophage and MDSC function and immunosuppression in the tumor microenvironment

scientific article published on 01 December 2019

GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3-dioxygenase.

artículo científico publicado en 2005

GVHD-associated, inflammasome-mediated loss of function in adoptively transferred myeloid-derived suppressor cells.

artículo científico publicado en 2015

Generation of cytotoxic T cells against virus-infected human brain macrophages in a murine model of HIV-1 encephalitis.

artículo científico publicado en 2002

Genome-wide DNA methylation analysis reveals novel epigenetic changes in chronic lymphocytic leukemia ⬇️

artículo científico publicado el 1 de junio de 2012

HLA-G transgenic mice

artículo científico publicado en 1999

Host indoleamine 2,3-dioxygenase: contribution to systemic acquired tumor tolerance.

artículo científico publicado en 2012

IDO inhibits a tryptophan sufficiency signal that stimulates mTOR: A novel IDO effector pathway targeted by D-1-methyl-tryptophan

artículo científico publicado en 2012

IL-7 signaling imparts polyfunctionality and stemness potential to CD4(+) T cells.

artículo científico publicado en 2016

Immunoglobulin Fc Fragment Tagging Allows Strong Activation of Endogenous CD4 T Cells To Reshape the Tumor Milieu and Enhance the Antitumor Effect of Lentivector Immunization ⬇️

artículo científico publicado el 13 de abril de 2012

Immunosuppressive myeloid cells induced by chemotherapy attenuate antitumor CD4+ T-cell responses through the PD-1-PD-L1 axis

artículo científico publicado en 2014

Indoleamine 2,3-dioxygenase 1 (ido1) is involved in the control of mouse caput epididymis immune environment

artículo científico publicado en 2013

Indoleamine 2,3-dioxygenase contributes to tumor cell evasion of T cell-mediated rejection.

artículo científico publicado en 2002

Indoleamine 2,3-dioxygenase controls conversion of Foxp3+ Tregs to TH17-like cells in tumor-draining lymph nodes.

artículo científico publicado en 2009

Indoleamine 2,3-dioxygenase in lung dendritic cells promotes Th2 responses and allergic inflammation

scientific journal article

Indoleamine 2,3-dioxygenase, Tregs and Cancer ⬇️

artículo científico publicado el 1 de enero de 2011

Indoleamine 2,3-dioxygenase-expressing mature human monocyte-derived dendritic cells expand potent autologous regulatory T cells.

scientific article published on 22 May 2009

Inhibition of indoleamine 2,3-dioxygenase (IDO) enhances elimination of virus-infected macrophages in an animal model of HIV-1 encephalitis

artículo científico publicado en 2005

Inhibition of inositol kinase B controls acute and chronic graft-versus-host disease

artículo científico publicado en 2020

Lentivector immunization stimulates potent CD8 T cell responses against melanoma self-antigen tyrosinase-related protein 1 and generates antitumor immunity in mice.

artículo científico publicado en 2009

Ligation of B7-1/B7-2 by human CD4+ T cells triggers indoleamine 2,3-dioxygenase activity in dendritic cells.

artículo científico publicado en 2004

Lineage-specific transcription factors in unexpected places.

artículo científico publicado en 2010

Local administration of TLR ligands rescues the function of tumor-infiltrating CD8 T cells and enhances the antitumor effect of lentivector immunization

artículo científico publicado en 2013

Maturation of antigen-presenting cells is compromised in HLA-G transgenic mice

artículo científico publicado en 2001

Monoclonal antibody 3F8 can effect durable remissions in neuroblastoma patients refractory to chemotherapy: a phase II trial

artículo científico publicado en 1991

Monocyte- and cytokine-induced downregulation of angiotensin-converting enzyme in cultured human and porcine endothelial cells

artículo científico publicado en 1996

Monocyte-induced downregulation of nitric oxide synthase in cultured aortic endothelial cells

scientific article published on 01 September 1996

Obesity related methylation changes in DNA of peripheral blood leukocytes ⬇️

artículo científico publicado el 21 de diciembre de 2010

P16-52. HIV-activated human plasmacytoid DCs induce Tregs through an indoleamine 2,3-dioxygenase-dependent mechanism.

artículo científico publicado en 2009

Pattern of recruitment of immunoregulatory antigen-presenting cells in malignant melanoma.

artículo científico publicado en 2003

Persistent STAT5 activation reprograms the epigenetic landscape in CD4+ T cells to drive polyfunctionality and antitumor immunity

artículo científico publicado en 2020

Phase II trial of murine monoclonal antibody D612 combined with recombinant human monocyte colony-stimulating factor (rhM-CSF) in patients with metastatic gastrointestinal cancer.

artículo científico publicado en 1995

Phase Ia study of the indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor navoximod (GDC-0919) in patients with recurrent advanced solid tumors.

artículo científico publicado en 2018

Physiologic Control of IDO Competence in Splenic Dendritic Cells ⬇️

artículo científico publicado el 3 de agosto de 2011

Polyfunctional CD4+ T cells are essential for eradicating advanced B-cell lymphoma after chemotherapy ⬇️

artículo científico publicado el 2 de agosto de 2012

Prevention of Allogeneic Fetal Rejection by Tryptophan Catabolism ⬇️

artículo científico publicado el 21 de agosto de 1998

Prevention of T cell-driven complement activation and inflammation by tryptophan catabolism during pregnancy.

artículo científico publicado en 2001

Program death-1 signaling and regulatory T cells collaborate to resist the function of adoptively transferred cytotoxic T lymphocytes in advanced acute myeloid leukemia.

artículo científico publicado en 2010

Promoter Methylation Modulates Indoleamine 2,3-Dioxygenase 1 Induction by Activated T Cells in Human Breast Cancers.

artículo científico publicado en 2017

Publisher Correction: ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression

scientific article published on 15 August 2019

Recombinant human macrophage colony-stimulating factor in nonhuman primates: selective expansion of a CD16+ monocyte subset with phenotypic similarity to primate natural killer cells.

artículo científico publicado en 1996

Role of low-affinity Fc receptors in antibody-dependent tumor cell phagocytosis by human monocyte-derived macrophages.

artículo científico publicado en 1991

STING Promotes the Growth of Tumors Characterized by Low Antigenicity via IDO Activation

artículo científico publicado en 2016

Selective activation-induced apoptosis of peripheral T cells imposed by macrophages. A potential mechanism of antigen-specific peripheral lymphocyte deletion

artículo científico publicado en 1996

TLR2-dependent activation of β-catenin pathway in dendritic cells induces regulatory responses and attenuates autoimmune inflammation

artículo científico publicado en 2014

Targeted Rho-associated kinase 2 inhibition suppresses murine and human chronic GVHD through a Stat3-dependent mechanism.

artículo científico publicado en 2016

Targeting PI3Kδ function for amelioration of murine chronic graft-versus-host disease

artículo científico publicado en 2019

Th17 cells in ovarian cancer

artículo científico publicado en 2009

The PTEN pathway in Tregs functions as a critical driver of the immunosuppressive tumor microenvironment and tolerance to apoptotic cells.

artículo científico publicado en 2015

The countervailing actions of myeloid and plasmacytoid dendritic cells control autoimmune diabetes in the nonobese diabetic mouse.

artículo científico publicado en 2007

Therapeutic regulatory T-cell adoptive transfer ameliorates established murine chronic GVHD in a CXCR5-dependent manner

artículo científico publicado en 2016

Tolerance to apoptotic cells is regulated by indoleamine 2,3-dioxygenase.

artículo científico publicado en 2012

Tolerogenic antigen-presenting cells.

artículo científico publicado en 2002

Toxicology and pharmacokinetics of 1-methyl-d-tryptophan: absence of toxicity due to saturating absorption.

artículo científico publicado en 2007

Tryptophan catabolism and T cell responses.

artículo científico publicado en 2003

Tryptophan catabolism prevents maternal T cells from activating lethal anti-fetal immune responses.

artículo científico publicado en 2001

Tumor-Expressed IDO Recruits and Activates MDSCs in a Treg-Dependent Manner

artículo científico publicado en 2015

Virus Infections Incite Pain Hypersensitivity by Inducing Indoleamine 2,3 Dioxygenase

artículo científico publicado en 2016

Zinc protoporphyrin IX stimulates tumor immunity by disrupting the immunosuppressive enzyme indoleamine 2,3-dioxygenase.

artículo científico publicado en 2010

miR-146b antagomir-treated human Tregs acquire increased GVHD inhibitory potency

artículo científico publicado en 2016

αVβ3 integrin regulates macrophage inflammatory responses via PI3 kinase/Akt-dependent NF-κB activation.

artículo científico publicado en 2011

Lista de obras de Munn DH

A novel immunohistochemical score to predict early mortality in acute myeloid leukemia patients based on indoleamine 2,3 dioxygenase expression

Activation of p53 in Immature Myeloid Precursor Cells Controls Differentiation into Ly6c+CD103+ Monocytic Antigen-Presenting Cells in Tumors

Activation of the STING adaptor attenuates experimental autoimmune encephalitis.

Activation-induced apoptosis in human macrophages: developmental regulation of a novel cell death pathway by macrophage colony-stimulating factor and interferon gamma.

Adjuvant IL-7 potentiates adoptive T cell therapy by amplifying and sustaining polyfunctional antitumor CD4+ T cells

Advanced Age Increases Immunosuppression in the Brain and Decreases Immunotherapeutic Efficacy in Subjects with Glioblastoma

An inherently bifunctional subset of Foxp3+ T helper cells is controlled by the transcription factor eos.

Antibody-independent phagocytosis of tumor cells by human monocyte-derived macrophages cultured in recombinant macrophage colony-stimulating factor ⬇️

Antigen-specific bacterial vaccine combined with anti-PD-L1 rescues dysfunctional endogenous T cells to reject long-established cancer.

Aortic endothelial cells regulate proliferation of human monocytes in vitro via a mechanism synergistic with macrophage colony-stimulating factor. Convergence at the cyclin E/p27(Kip1) regulatory checkpoint

Apoptotic cell-induced AhR activity is required for immunological tolerance and suppression of systemic lupus erythematosus in mice and humans

B-lymphoid cells with attributes of dendritic cells regulate T cells via indoleamine 2,3-dioxygenase

Blockade of programmed death-1 pathway rescues the effector function of tumor-infiltrating T cells and enhances the antitumor efficacy of lentivector immunization.

Blocking IDO activity to enhance anti-tumor immunity.

Butyrate suppresses colonic inflammation through HDAC1-dependent Fas upregulation and Fas-mediated apoptosis of T cells.

CD73 on cancer-associated fibroblasts enhanced by the A2B-mediated feedforward circuit enforces an immune checkpoint

Canonical wnt signaling in dendritic cells regulates Th1/Th17 responses and suppresses autoimmune neuroinflammation

Cell-autonomous control of interferon type I expression by indoleamine 2,3-dioxygenase in regulatory CD19+ dendritic cells.

Cells expressing indoleamine 2,3-dioxygenase inhibit T cell responses.

Chemo-Immunotherapy: Role of Indoleamine 2,3-Dioxygenase in Defining Immunogenic Versus Tolerogenic Cell Death in the Tumor Microenvironment

Chronic inflammation that facilitates tumor progression creates local immune suppression by inducing indoleamine 2,3 dioxygenase.

Creating immune privilege: active local suppression that benefits friends, but protects foes.

Cutting edge: DNA sensing via the STING adaptor in myeloid dendritic cells induces potent tolerogenic responses

Cutting edge: induced indoleamine 2,3 dioxygenase expression in dendritic cell subsets suppresses T cell clonal expansion.

Cytokine regulation of human monocyte differentiation in vitro: the tumor-cytotoxic phenotype induced by macrophage colony-stimulating factor is developmentally regulated by gamma-interferon

Danger-associated extracellular ATP counters MDSC therapeutic efficacy in acute GVHD

Decreased protein nitration in macrophages that overexpress indoleamine 2, 3-dioxygenase

Deficient tryptophan catabolism along the kynurenine pathway reveals that the epididymis is in a unique tolerogenic state.

Deletion of LRP5 and LRP6 in dendritic cells enhances antitumor immunity.

Dendritic Cell Expression of Retinal Aldehyde Dehydrogenase-2 Controls Graft-versus-Host Disease Lethality

Dendritic cells have the option to express IDO-mediated suppression or not

Donor and host B7-H4 expression negatively regulates acute graft-versus-host disease lethality

ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression

Engineering DNA Nanoparticles as Immunomodulatory Reagents that Activate Regulatory T Cells ⬇️

Epitope-optimized alpha-fetoprotein genetic vaccines prevent carcinogen-induced murine autochthonous hepatocellular carcinoma

Expression of indoleamine 2,3-dioxygenase by plasmacytoid dendritic cells in tumor-draining lymph nodes.

GCN2 drives macrophage and MDSC function and immunosuppression in the tumor microenvironment

GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3-dioxygenase.

GVHD-associated, inflammasome-mediated loss of function in adoptively transferred myeloid-derived suppressor cells.

Generation of cytotoxic T cells against virus-infected human brain macrophages in a murine model of HIV-1 encephalitis.

Genome-wide DNA methylation analysis reveals novel epigenetic changes in chronic lymphocytic leukemia ⬇️

HLA-G transgenic mice

Host indoleamine 2,3-dioxygenase: contribution to systemic acquired tumor tolerance.

IDO inhibits a tryptophan sufficiency signal that stimulates mTOR: A novel IDO effector pathway targeted by D-1-methyl-tryptophan

IL-7 signaling imparts polyfunctionality and stemness potential to CD4(+) T cells.

Immunoglobulin Fc Fragment Tagging Allows Strong Activation of Endogenous CD4 T Cells To Reshape the Tumor Milieu and Enhance the Antitumor Effect of Lentivector Immunization ⬇️

Immunosuppressive myeloid cells induced by chemotherapy attenuate antitumor CD4+ T-cell responses through the PD-1-PD-L1 axis

Indoleamine 2,3-dioxygenase 1 (ido1) is involved in the control of mouse caput epididymis immune environment

Indoleamine 2,3-dioxygenase contributes to tumor cell evasion of T cell-mediated rejection.

Indoleamine 2,3-dioxygenase controls conversion of Foxp3+ Tregs to TH17-like cells in tumor-draining lymph nodes.

Indoleamine 2,3-dioxygenase in lung dendritic cells promotes Th2 responses and allergic inflammation

Indoleamine 2,3-dioxygenase, Tregs and Cancer ⬇️

Indoleamine 2,3-dioxygenase-expressing mature human monocyte-derived dendritic cells expand potent autologous regulatory T cells.

Inhibition of indoleamine 2,3-dioxygenase (IDO) enhances elimination of virus-infected macrophages in an animal model of HIV-1 encephalitis

Inhibition of inositol kinase B controls acute and chronic graft-versus-host disease

Lentivector immunization stimulates potent CD8 T cell responses against melanoma self-antigen tyrosinase-related protein 1 and generates antitumor immunity in mice.

Ligation of B7-1/B7-2 by human CD4+ T cells triggers indoleamine 2,3-dioxygenase activity in dendritic cells.

Lineage-specific transcription factors in unexpected places.

Local administration of TLR ligands rescues the function of tumor-infiltrating CD8 T cells and enhances the antitumor effect of lentivector immunization

Maturation of antigen-presenting cells is compromised in HLA-G transgenic mice

Monoclonal antibody 3F8 can effect durable remissions in neuroblastoma patients refractory to chemotherapy: a phase II trial

Monocyte- and cytokine-induced downregulation of angiotensin-converting enzyme in cultured human and porcine endothelial cells

Monocyte-induced downregulation of nitric oxide synthase in cultured aortic endothelial cells

Obesity related methylation changes in DNA of peripheral blood leukocytes ⬇️

P16-52. HIV-activated human plasmacytoid DCs induce Tregs through an indoleamine 2,3-dioxygenase-dependent mechanism.

Pattern of recruitment of immunoregulatory antigen-presenting cells in malignant melanoma.

Persistent STAT5 activation reprograms the epigenetic landscape in CD4+ T cells to drive polyfunctionality and antitumor immunity

Phase II trial of murine monoclonal antibody D612 combined with recombinant human monocyte colony-stimulating factor (rhM-CSF) in patients with metastatic gastrointestinal cancer.

Phase Ia study of the indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor navoximod (GDC-0919) in patients with recurrent advanced solid tumors.

Physiologic Control of IDO Competence in Splenic Dendritic Cells ⬇️

Polyfunctional CD4+ T cells are essential for eradicating advanced B-cell lymphoma after chemotherapy ⬇️

Prevention of Allogeneic Fetal Rejection by Tryptophan Catabolism ⬇️

Prevention of T cell-driven complement activation and inflammation by tryptophan catabolism during pregnancy.

Program death-1 signaling and regulatory T cells collaborate to resist the function of adoptively transferred cytotoxic T lymphocytes in advanced acute myeloid leukemia.

Promoter Methylation Modulates Indoleamine 2,3-Dioxygenase 1 Induction by Activated T Cells in Human Breast Cancers.

Publisher Correction: ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression

Recombinant human macrophage colony-stimulating factor in nonhuman primates: selective expansion of a CD16+ monocyte subset with phenotypic similarity to primate natural killer cells.

Role of low-affinity Fc receptors in antibody-dependent tumor cell phagocytosis by human monocyte-derived macrophages.

STING Promotes the Growth of Tumors Characterized by Low Antigenicity via IDO Activation