Lista de obras - Annika Scheffold - Dominio Público Uruguay

ATM-dependent phosphorylation of SNEVhPrp19/hPso4 is involved in extending cellular life span and suppression of apoptosis

artículo científico publicado en 2012

Anti-Leukemia Activity of the Selective BCL-2 Inhibitor ABT-199 in Childhood B-Cell Precursor Acute Lymphoblastic Leukemia Is Characterized By MCL-1/BCL-2 Expression Serving As Biomarker for Treatment Response ⬇️

scholarly article

Elevated Hedgehog activity contributes to attenuated DNA damage responses in aged hematopoietic cells

artículo científico publicado en 2019

Functional characterization of BRCC3 mutations in acute myeloid leukemia with t(8;21)(q22;q22.1)

artículo científico publicado en 2019

Generation of a lenalidomide-sensitive syngeneic murine in vivo multiple myeloma model by expression of CrbnI391V

artículo científico publicado en 2020

IGF1R as druggable target mediating PI3K-δ inhibitor resistance in a murine model of chronic lymphocytic leukemia

scientific article published on 22 April 2019

Impact of telomere length on the outcome of allogeneic stem cell transplantation for poor-risk chronic lymphocytic leukaemia: results from the GCLLSG CLL3X trial.

artículo científico publicado en 2016

Mutual exacerbation of peroxisome proliferator-activated receptor γ coactivator 1α deregulation and α-synuclein oligomerization

artículo científico publicado en 2014

Oxidative stress as candidate therapeutic target to overcome microenvironmental protection of CLL

scientific article published on 12 July 2019

PI3Kδ inhibition modulates regulatory and effector T-cell differentiation and function in chronic lymphocytic leukemia

scientific article published on 20 December 2018

Prediction of venetoclax activity in precursor B-ALL by functional assessment of apoptosis signaling

artículo científico publicado en 2019

Reconstruction of rearranged T-cell receptor loci by whole genome and transcriptome sequencing gives insights into the initial steps of T-cell prolymphocytic leukemia

scientific article published on 29 November 2019

Revolution of Chronic Lymphocytic Leukemia Therapy: the Chemo-Free Treatment Paradigm

artículo científico publicado en 2020

Short telomeres are associated with inferior outcome, genomic complexity, and clonal evolution in chronic lymphocytic leukemia

scientific article published on 25 March 2019

Substantial telomere shortening in the substantia nigra of telomerase-deficient mice does not increase susceptibility to MPTP-induced dopamine depletion.

artículo científico publicado en 2014

TBET-expressing Th1 CD4+ T cells accumulate in chronic lymphocytic leukaemia without affecting disease progression in Eµ-TCL1 mice

artículo científico publicado en 2019

Telomerase gene mutations are associated with cirrhosis formation

artículo científico publicado en 2011

Telomere Lenght and Outcome of Allogeneic Stem Cell Transplantation for Poor Risk Chronic Lymphocytic Leukemia: Results from the GCLLSG CLL3X Trial ⬇️

scholarly article

Telomere length in poor-risk chronic lymphocytic leukemia: associations with disease characteristics and outcome

artículo científico publicado en 2017

Telomere shortening leads to an acceleration of synucleinopathy and impaired microglia response in a genetic mouse model

artículo científico publicado en 2016

Telomere shortening leads to earlier age of onset in ALS mice

artículo científico publicado en 2016

Telomere shortening reduces Alzheimer's disease amyloid pathology in mice

artículo científico publicado en 2011

Thirty-eight-negative kinase 1 mediates trauma-induced intestinal injury and multi-organ failure

Transient telomere dysfunction induces chromosomal instability and promotes carcinogenesis

artículo científico publicado en 2021

Transient telomere dysfunction induces chromosomal instability and promotes carcinogenesis.

artículo científico publicado en 2012

Vecabrutinib Is Efficacious In Vivo in a Preclinical CLL Adoptive Transfer Model ⬇️

artículo científico publicado en 2018

Venetoclax: Targeting BCL2 in Hematological Cancers

artículo científico publicado en 2018

Whole-Exome Sequencing Revealed No Recurrent Mutations within the PI3K Pathway in Relapsed Chronic Lymphocytic Leukemia Patients Progressing Under Idelalisib Treatment ⬇️

artículo científico publicado en 2016

YAP Activation Drives Liver Regeneration after Cholestatic Damage Induced by Deletion

article published in 2018

Lista de obras de Annika Scheffold

ATM-dependent phosphorylation of SNEVhPrp19/hPso4 is involved in extending cellular life span and suppression of apoptosis

Anti-Leukemia Activity of the Selective BCL-2 Inhibitor ABT-199 in Childhood B-Cell Precursor Acute Lymphoblastic Leukemia Is Characterized By MCL-1/BCL-2 Expression Serving As Biomarker for Treatment Response ⬇️

Elevated Hedgehog activity contributes to attenuated DNA damage responses in aged hematopoietic cells

Functional characterization of BRCC3 mutations in acute myeloid leukemia with t(8;21)(q22;q22.1)

Generation of a lenalidomide-sensitive syngeneic murine in vivo multiple myeloma model by expression of CrbnI391V

IGF1R as druggable target mediating PI3K-δ inhibitor resistance in a murine model of chronic lymphocytic leukemia

Impact of telomere length on the outcome of allogeneic stem cell transplantation for poor-risk chronic lymphocytic leukaemia: results from the GCLLSG CLL3X trial.

Mutual exacerbation of peroxisome proliferator-activated receptor γ coactivator 1α deregulation and α-synuclein oligomerization

Oxidative stress as candidate therapeutic target to overcome microenvironmental protection of CLL

PI3Kδ inhibition modulates regulatory and effector T-cell differentiation and function in chronic lymphocytic leukemia

Prediction of venetoclax activity in precursor B-ALL by functional assessment of apoptosis signaling

Reconstruction of rearranged T-cell receptor loci by whole genome and transcriptome sequencing gives insights into the initial steps of T-cell prolymphocytic leukemia

Revolution of Chronic Lymphocytic Leukemia Therapy: the Chemo-Free Treatment Paradigm

Short telomeres are associated with inferior outcome, genomic complexity, and clonal evolution in chronic lymphocytic leukemia

Substantial telomere shortening in the substantia nigra of telomerase-deficient mice does not increase susceptibility to MPTP-induced dopamine depletion.

TBET-expressing Th1 CD4+ T cells accumulate in chronic lymphocytic leukaemia without affecting disease progression in Eµ-TCL1 mice

Telomerase gene mutations are associated with cirrhosis formation

Telomere Lenght and Outcome of Allogeneic Stem Cell Transplantation for Poor Risk Chronic Lymphocytic Leukemia: Results from the GCLLSG CLL3X Trial ⬇️

Telomere length in poor-risk chronic lymphocytic leukemia: associations with disease characteristics and outcome

Telomere shortening leads to an acceleration of synucleinopathy and impaired microglia response in a genetic mouse model

Telomere shortening leads to earlier age of onset in ALS mice

Telomere shortening reduces Alzheimer's disease amyloid pathology in mice

Thirty-eight-negative kinase 1 mediates trauma-induced intestinal injury and multi-organ failure

Transient telomere dysfunction induces chromosomal instability and promotes carcinogenesis

Transient telomere dysfunction induces chromosomal instability and promotes carcinogenesis.

Vecabrutinib Is Efficacious In Vivo in a Preclinical CLL Adoptive Transfer Model ⬇️

Venetoclax: Targeting BCL2 in Hematological Cancers

Whole-Exome Sequencing Revealed No Recurrent Mutations within the PI3K Pathway in Relapsed Chronic Lymphocytic Leukemia Patients Progressing Under Idelalisib Treatment ⬇️

YAP Activation Drives Liver Regeneration after Cholestatic Damage Induced by Deletion