Lista de obras - Itzhaki L - Dominio Público Uruguay

A New Methodology for Incorporating Chiral Linkers into Stapled Peptides

artículo científico publicado en 2017

A unique binding cavity for divalent cations in the DNA-metal-chromomycin A3 complex

artículo científico publicado en 1990

A virus that can take the heat.

artículo científico publicado en 2014

ATPase site architecture and helicase mechanism of an archaeal MCM.

artículo científico publicado en 2007

Alcohol oxidase (AOX1) from Pichia pastoris is a novel inhibitor of prion propagation and a potential ATPase.

artículo científico publicado en 2008

Auxetics at the Molecular Level: A Negative Poisson's Ratio in Molecular Rods

artículo científico publicado en 2006

Binding of EMSY to HP1beta: implications for recruitment of HP1beta and BS69

artículo científico publicado en 2005

Biophysical characterisation of the small ankyrin repeat protein myotrophin.

artículo científico publicado en 2006

Characterisation of the BRCT Domains of the Breast Cancer Susceptibility Gene Product BRCA1

article

Characterising the binding specificities of the subunits associated with the KMT2/Set1 histone lysine methyltransferase.

artículo científico publicado en 2010

Comparison of BRCT domains of BRCA1 and 53BP1: a biophysical analysis

artículo científico publicado en 2004

Complementation of peptide fragments of the single domain protein chymotrypsin inhibitor 2

artículo científico publicado en 1997

Complex regulation controls Neurogenin3 proteolysis.

artículo científico publicado en 2012

Conjugation in polyyne rods: to what extent is charge delocalization coupled to geometrical changes?

scientific article published on 01 December 2008

Cooperative organization in a macromolecular complex

artículo científico publicado en 2003

Crystal structure of the ENT domain of human EMSY.

artículo científico publicado en 2005

Development of Cell-Permeable, Non-Helical Constrained Peptides to Target a Key Protein-Protein Interaction in Ovarian Cancer

artículo científico publicado en 2016

Diffuse transition state structure for the unfolding of a leucine-rich repeat protein.

artículo científico publicado en 2014

Discovery of a small-molecule binder of the oncoprotein gankyrin that modulates gankyrin activity in the cell

artículo científico publicado en 2016

Dissecting and reprogramming the folding and assembly of tandem-repeat proteins

artículo científico publicado en 2015

Domain swapping in p13suc1 results in formation of native-like, cytotoxic aggregates.

artículo científico publicado en 2006

Exploring new strategies for grafting binding peptides onto protein loops using a consensus-designed tetratricopeptide repeat scaffold

scientific article published on 01 April 2019

Folding and Association of the Human Cell Cycle Regulatory Proteins ckshs1 and ckshs2†

artículo científico publicado en 2002

Folding and binding: lingering questions, emerging answers

scientific article published on 20 January 2012

Folding and fibril formation of the cell cycle protein Cks1

scientific article published on 04 May 2006

Folding cooperativity and allosteric function in the tandem-repeat protein class

artículo científico publicado en 2018

Folding of a nascent polypeptide chain in vitro: cooperative formation of structure in a protein module.

artículo científico publicado en 1995

Following co-operative formation of secondary and tertiary structure in a single protein module

artículo científico publicado en 1997

From artificial antibodies to nanosprings: the biophysical properties of repeat proteins.

artículo científico

Functionalized Double Strain-Promoted Stapled Peptides for Inhibiting the p53-MDM2 Interaction

artículo científico publicado en 2020

Hsp40 interacts directly with the native state of the yeast prion protein Ure2 and inhibits formation of amyloid-like fibrils

artículo científico publicado en 2007

Hydrogen exchange and protein folding.

artículo científico publicado en 1998

Hydrogen exchange at equilibrium: a short cut for analysing protein-folding pathways? ⬇️

artículo científico publicado el 1 de agosto de 1997

Hydrogen exchange in chymotrypsin inhibitor 2 probed by denaturants and temperature ⬇️

artículo científico publicado el 4 de julio de 1997

Hydrogen exchange in chymotrypsin inhibitor 2 probed by mutagenesis

artículo científico publicado en 1997

Implications of 3D domain swapping for protein folding, misfolding and function.

artículo científico publicado en 2012

Influence of specific HSP70 domains on fibril formation of the yeast prion protein Ure2

artículo científico publicado en 2013

Intermediates control domain swapping during folding of p13suc1.

artículo científico publicado en 2003

Macrocyclized Extended Peptides: Inhibiting the Substrate-Recognition Domain of Tankyrase.

scientific article published on 13 January 2017

Mapping the Topography of a Protein Energy Landscape.

artículo científico publicado en 2015

Movement of the position of the transition state in protein folding

artículo científico publicado en 1995

Nanoscale click-reactive scaffolds from peptide self-assembly.

artículo científico publicado en 2017

Nature and nurture in protein folding and binding

artículo científico publicado en 2010

Observation of signal transduction in three-dimensional domain swapping

artículo científico publicado en 2001

Probing a moving target with a plastic unfolding intermediate of an ankyrin-repeat protein.

artículo científico publicado en 2007

Programmed Protein Self-Assembly Driven by Genetically Encoded Intein-Mediated Native Chemical Ligation.

artículo científico publicado en 2018

Protein folding: When ribosomes pick the structure

artículo científico publicado en 2014

Protein stability versus function: effects of destabilizing missense mutations onBRCA1DNA repair activity

artículo científico publicado en 2015

Search for nucleation sites in smaller fragments of chymotrypsin inhibitor 2.

artículo científico publicado en 1995

Single versus parallel pathways of protein folding and fractional formation of structure in the transition state

artículo científico publicado en 1994

Single-molecule FRET reveals hidden complexity in a protein energy landscape.

artículo científico publicado en 2015

Stability and folding of the cell cycle regulatory protein, p13 suc1 1 1Edited by F. E. Cohen

scientific article published on 01 November 1998

Stability and folding of the tumour suppressor protein p16

artículo científico publicado en 1999

Strain in the folding nucleus of chymotrypsin inhibitor 2

artículo científico publicado en 1997

Structure of the transition state for the folding/unfolding of the barley chymotrypsin inhibitor 2 and its implications for mechanisms of protein folding.

artículo científico publicado en 1994

Structure-Based Discovery of Lipoteichoic Acid Synthase Inhibitors

scientific article published on 09 May 2022

Subdomain architecture and stability of a giant repeat protein.

artículo científico publicado en 2013

Targeted covalent inhibitors of MDM2 using electrophile-bearing stapled peptides

artículo científico publicado en 2019

Tertiary interactions in the folding pathway of hen lysozyme: kinetic studies using fluorescent probes.

artículo científico publicado en 1994

The Structure of the Transition State for Folding of Chymotrypsin Inhibitor 2 Analysed by Protein Engineering Methods: Evidence for a Nucleation-condensation Mechanism for Protein Folding

article

The folding pathway of the cell-cycle regulatory protein p13suc1: clues for the mechanism of domain swapping

artículo científico publicado en 2000

The how's and why's of protein folding intermediates.

artículo científico publicado en 2012

The quest to understand protein folding

artículo científico publicado en 2008

The structure of the transition state for folding of domain-swapped dimeric p13suc1.

artículo científico publicado en 2002

The unfolding story of three-dimensional domain swapping.

artículo científico publicado en 2003

Three-dimensional domain swapping in p13suc1 occurs in the unfolded state and is controlled by conserved proline residues.

artículo científico publicado en 2001

Toolbox of Diverse Linkers for Navigating the Cellular Efficacy Landscape of Stapled Peptides

artículo científico publicado en 2019

Toward classification of BRCA1 missense variants using a biophysical approach.

artículo científico publicado en 2010

Using FlAsH to probe conformational changes in a large HEAT repeat protein.

artículo científico publicado en 2012

Lista de obras de Itzhaki L

A New Methodology for Incorporating Chiral Linkers into Stapled Peptides

A unique binding cavity for divalent cations in the DNA-metal-chromomycin A3 complex

A virus that can take the heat.

ATPase site architecture and helicase mechanism of an archaeal MCM.

Alcohol oxidase (AOX1) from Pichia pastoris is a novel inhibitor of prion propagation and a potential ATPase.

Auxetics at the Molecular Level: A Negative Poisson's Ratio in Molecular Rods

Binding of EMSY to HP1beta: implications for recruitment of HP1beta and BS69

Biophysical characterisation of the small ankyrin repeat protein myotrophin.

Characterisation of the BRCT Domains of the Breast Cancer Susceptibility Gene Product BRCA1

Characterising the binding specificities of the subunits associated with the KMT2/Set1 histone lysine methyltransferase.

Comparison of BRCT domains of BRCA1 and 53BP1: a biophysical analysis

Complementation of peptide fragments of the single domain protein chymotrypsin inhibitor 2

Complex regulation controls Neurogenin3 proteolysis.

Conjugation in polyyne rods: to what extent is charge delocalization coupled to geometrical changes?

Cooperative organization in a macromolecular complex

Crystal structure of the ENT domain of human EMSY.

Development of Cell-Permeable, Non-Helical Constrained Peptides to Target a Key Protein-Protein Interaction in Ovarian Cancer

Diffuse transition state structure for the unfolding of a leucine-rich repeat protein.

Discovery of a small-molecule binder of the oncoprotein gankyrin that modulates gankyrin activity in the cell

Dissecting and reprogramming the folding and assembly of tandem-repeat proteins

Domain swapping in p13suc1 results in formation of native-like, cytotoxic aggregates.

Exploring new strategies for grafting binding peptides onto protein loops using a consensus-designed tetratricopeptide repeat scaffold

Folding and Association of the Human Cell Cycle Regulatory Proteins ckshs1 and ckshs2†

Folding and binding: lingering questions, emerging answers

Folding and fibril formation of the cell cycle protein Cks1

Folding cooperativity and allosteric function in the tandem-repeat protein class

Folding of a nascent polypeptide chain in vitro: cooperative formation of structure in a protein module.

Following co-operative formation of secondary and tertiary structure in a single protein module

From artificial antibodies to nanosprings: the biophysical properties of repeat proteins.

Functionalized Double Strain-Promoted Stapled Peptides for Inhibiting the p53-MDM2 Interaction

Hsp40 interacts directly with the native state of the yeast prion protein Ure2 and inhibits formation of amyloid-like fibrils

Hydrogen exchange and protein folding.

Hydrogen exchange at equilibrium: a short cut for analysing protein-folding pathways? ⬇️

Hydrogen exchange in chymotrypsin inhibitor 2 probed by denaturants and temperature ⬇️

Hydrogen exchange in chymotrypsin inhibitor 2 probed by mutagenesis

Implications of 3D domain swapping for protein folding, misfolding and function.

Influence of specific HSP70 domains on fibril formation of the yeast prion protein Ure2

Intermediates control domain swapping during folding of p13suc1.

Macrocyclized Extended Peptides: Inhibiting the Substrate-Recognition Domain of Tankyrase.

Mapping the Topography of a Protein Energy Landscape.

Movement of the position of the transition state in protein folding

Nanoscale click-reactive scaffolds from peptide self-assembly.

Nature and nurture in protein folding and binding

Observation of signal transduction in three-dimensional domain swapping

Probing a moving target with a plastic unfolding intermediate of an ankyrin-repeat protein.

Programmed Protein Self-Assembly Driven by Genetically Encoded Intein-Mediated Native Chemical Ligation.

Protein folding: When ribosomes pick the structure

Protein stability versus function: effects of destabilizing missense mutations onBRCA1DNA repair activity

Search for nucleation sites in smaller fragments of chymotrypsin inhibitor 2.

Single versus parallel pathways of protein folding and fractional formation of structure in the transition state

Single-molecule FRET reveals hidden complexity in a protein energy landscape.

Stability and folding of the cell cycle regulatory protein, p13 suc1 1 1Edited by F. E. Cohen

Stability and folding of the tumour suppressor protein p16

Strain in the folding nucleus of chymotrypsin inhibitor 2

Structure of the transition state for the folding/unfolding of the barley chymotrypsin inhibitor 2 and its implications for mechanisms of protein folding.

Structure-Based Discovery of Lipoteichoic Acid Synthase Inhibitors

Subdomain architecture and stability of a giant repeat protein.

Targeted covalent inhibitors of MDM2 using electrophile-bearing stapled peptides

Tertiary interactions in the folding pathway of hen lysozyme: kinetic studies using fluorescent probes.

The Structure of the Transition State for Folding of Chymotrypsin Inhibitor 2 Analysed by Protein Engineering Methods: Evidence for a Nucleation-condensation Mechanism for Protein Folding

The folding pathway of the cell-cycle regulatory protein p13suc1: clues for the mechanism of domain swapping

The how's and why's of protein folding intermediates.

The quest to understand protein folding

The structure of the transition state for folding of domain-swapped dimeric p13suc1.

The unfolding story of three-dimensional domain swapping.

Three-dimensional domain swapping in p13suc1 occurs in the unfolded state and is controlled by conserved proline residues.

Toolbox of Diverse Linkers for Navigating the Cellular Efficacy Landscape of Stapled Peptides

Toward classification of BRCA1 missense variants using a biophysical approach.

Using FlAsH to probe conformational changes in a large HEAT repeat protein.