Lista de obras - M W Coughtrie - Dominio Público Uruguay

A Novel Method for the Immunoquantification of UDP-Glucuronosyltransferases in Human Tissue ⬇️

artículo científico publicado el 31 de agosto de 2011

A case of heavy chain disease: diagnosis and monitoring using assays of immunoglobulin heavy and light chains

artículo científico publicado en 1990

A general assay for UDPglucuronosyltransferase activity using polar amino-cyano stationary phase HPLC and UDP[U-14C]glucuronic acid.

artículo científico publicado en 1986

A single amino acid, glu146, governs the substrate specificity of a human dopamine sulfotransferase, SULT1A3

artículo científico publicado en 1998

Absolute immunoquantification of the expression of ABC transporters P-glycoprotein, breast cancer resistance protein and multidrug resistance-associated protein 2 in human liver and duodenum

artículo científico publicado en 2011

Activation of benzylic alcohols to mutagens by human hepatic sulphotransferases.

artículo científico publicado en 1994

Antiplatelet drug interactions.

artículo científico publicado en 2010

Assessment of cryopreserved human hepatocytes as a model system to investigate sulfation and glucuronidation and to evaluate inhibitors of drug conjugation

artículo científico publicado en 2009

Catecholamine Sulfation in Health and Disease

artículo científico publicado el 1 de enero de 1998

Characterization of bovine phenol sulfotransferases: evidence of a major role for SULT1B1 in the liver

artículo científico publicado en 2014

Chondroitin sulfate N-acetylgalactosaminyltransferase-1 (CSGalNAcT-1) involved in chondroitin sulfate initiation: Impact of sulfation on activity and specificity.

artículo científico publicado en 2011

CoMFA modeling of enzyme kinetics: K(m) values for sulfation of diverse phenolic substrates by human catecholamine sulfotransferase SULT1A3.

artículo científico publicado en 2003

Common food additives are potent inhibitors of human liver 17 alpha-ethinyloestradiol and dopamine sulphotransferases

scientific article published on 01 November 1993

Comparison of 2-aminophenol and 4-nitrophenol as in vitro probe substrates for the major human hepatic sulfotransferase, SULT1A1, demonstrates improved selectivity with 2-aminophenol.

artículo científico publicado en 2007

Conjugation of catechols by recombinant human sulfotransferases, UDP-glucuronosyltransferases, and soluble catechol O-methyltransferase: structure-conjugation relationships and predictive models.

artículo científico publicado en 2003

Cytosolic phenol and steroid sulphotransferase activities are decreased in a sex-dependent manner in streptozotocin-induced diabetic rats

artículo científico publicado en 1990

Dehydroepiandrosterone sulfotransferase in the developing human fetus: quantitative biochemical and immunological characterization of the hepatic, renal, and adrenal enzymes.

artículo científico publicado en 1994

Design, production and characterization of antibodies discriminating between the phenol- and monoamine-sulphating forms of human phenol sulphotransferase

artículo científico publicado en 1996

Differential Expression of Sulfotransferase Enzymes Involved in Thyroid Hormone Metabolism during Human Placental Development ⬇️

artículo científico publicado el 1 de diciembre de 2001

Differential localisation of UDP-glucuronosyltransferase in kidney during human embryonic and fetal development

artículo científico publicado en 1995

Down-regulation of dehydroepiandrosterone sulfotransferase gene in human hepatocellular carcinoma

scientific article published on 08 December 2004

Effect of structurally diverse peroxisome proliferators on rat hepatic sulfotransferase.

artículo científico publicado en 1996

Effects of hypophysectomy and thyroxine on the expression of hepatic oestrogen, hydroxysteroid and phenol sulphotransferases

artículo científico publicado en 1995

Estrogen and phenol sulfotransferase activities in human fetal lung

scientific article published on 01 January 1992

Expression profiling of human fetal cytosolic sulfotransferases involved in steroid and thyroid hormone metabolism and in detoxification

artículo científico publicado en 2005

Farnesol is glucuronidated in human liver, kidney and intestine in vitro, and is a novel substrate for UGT2B7 and UGT1A1.

artículo científico publicado en 2004

Function and organization of the human cytosolic sulfotransferase (SULT) family.

artículo científico publicado en 2016

Function and regulation of UDP-glucuronosyltransferase genes in health and liver disease: report of the Seventh International Workshop on Glucuronidation, September 1993, Pitlochry, Scotland.

artículo científico publicado en 1994

Glucuronidation of imipramine in rabbit and human liver microsomes: assay conditions and interaction with other tertiary amine drugs

artículo científico publicado en 1991

Heterogeneous expression of sulphotransferases in periportal and perivenous hepatocytes prepared from male and female rat liver.

artículo científico publicado en 1996

Human Platelet Phenolsulfotransferases: cDNA Cloning, Stable Expression in V79 Cells, and Identification of a Novel Allelic Variant of the Phenol-Sulfating Form ⬇️

artículo científico publicado el 17 de marzo de 1995

Human fetal adrenal hydroxysteroid sulphotransferase: cDNA cloning, stable expression in V79 cells and functional characterisation of the expressed enzyme.

artículo científico publicado en 1995

Identification of a new adult human liver sulfotransferase with specificity for endogenous and xenobiotic estrogens

scientific article published on 01 January 1994

Immunochemical characterisation of a dehydroepiandrosterone sulfotransferase in rats and humans

scientific journal article

Immunochemical identification of hepatic protein adducts derived from estragole.

artículo científico publicado en 1998

Immunohistochemical localisation of hydroxysteroid sulphotransferase in human breast carcinoma tissue: a preliminary study

scientific article published on 01 January 1994

Induction of hepatic estrogen sulfotransferase expression by hypophysectomy in female rats

scientific article published on 01 November 1995

Influence of Morbid Obesity on the Pharmacokinetics of Morphine, Morphine-3-Glucuronide, and Morphine-6-Glucuronide

artículo científico

Inhibition of UDP-glucuronosyltransferase activity by possible transition-state analogues in rat-liver microsomes

artículo científico publicado en 1990

Inhibition of human liver steroid sulfotransferase activities by drugs: a novel mechanism of drug toxicity?

artículo científico publicado en 1992

Inhibition of thyroid hormone sulfation by hydroxylated metabolites of polychlorinated biphenyls ⬇️

artículo científico publicado el 20 de febrero de 1998

Investigation of the molecular basis of the genetic deficiency of UDP-glucuronosyltransferase in Crigler-Najjar syndrome.

artículo científico publicado en 1991

Liver-specific expression of paracetamol sulphotransferase

scientific article published on 01 December 1990

Luminal accumulation of newly synthesized morphine-3-glucuronide in rat liver microsomal vesicles

artículo científico publicado en 2012

Molecular and functional characterization of microsomal UDP-glucuronic acid uptake by members of the nucleotide sugar transporter (NST) family

artículo científico publicado en 2006

Molecular basis for acceptor substrate specificity of the human beta1,3-glucuronosyltransferases GlcAT-I and GlcAT-P involved in glycosaminoglycan and HNK-1 carbohydrate epitope biosynthesis, respectively

scientific article published on 13 June 2007

Molecular characterization of β1,4‐galactosyltransferase 7 genetic mutations linked to the progeroid form of Ehlers–Danlos syndrome (EDS) ⬇️

artículo científico publicado el 6 de agosto de 2010

N-glucuronidation of carbamazepine in human tissues is mediated by UGT2B7.

artículo científico publicado en 2004

Neonatal development of hepatic UGT1A9: implications of pediatric pharmacokinetics.

artículo científico publicado en 2012

Ontogeny of Human Conjugating Enzymes.

artículo científico

Phenol sulfotransferase 1A1 activity in human liver: kinetic properties, interindividual variation and re-evaluation of the suitability of 4-nitrophenol as a probe substrate ⬇️

artículo científico publicado el 1 de diciembre de 2003

Phenol sulphotransferase SULT1A1*1 genotype is associated with reduced risk of colorectal cancer

artículo científico publicado en 2001

Phenolsulphotransferase: localization in kidney during human embryonic and fetal development

artículo científico publicado en 1994

Preparation and characterization of anti-peptide antibodies directed against human phenol and hydroxysteroid sulphotransferases

scientific article published on 01 October 1995

Purification and immunochemical characterization of a rat liver sulphotransferase conjugating paracetamol

artículo científico publicado en 1990

Purification and properties of rat kidney UDP-glucuronosyltransferase

scientific article published on 01 January 1987

Quantitative evaluation of the expression and activity of five major sulfotransferases (SULTs) in human tissues: the SULT "pie".

artículo científico publicado en 2009

Reduced platelet phenolsulphotransferase activity towards dopamine and 5-hydroxytryptamine in migraine

artículo científico publicado en 1995

Regioselective sulfonation of dopamine by SULT1A3 in vitro provides a molecular explanation for the preponderance of dopamine-3-O-sulfate in human blood circulation

scientific article published on 10 May 2007

Revisiting the Latency of Uridine Diphosphate-Glucuronosyltransferases (UGTs)-How Does the Endoplasmic Reticulum Membrane Influence Their Function?

artículo científico publicado en 2017

Selective induction of bilirubin UDP-glucuronosyl-transferase by perfluorodecanoic acid

scientific article published on 01 January 1991

Steroid sulphates inhibit the rat hepatic microsomal glucose-6-phosphatase system

scientific article published on 01 May 1991

Substrate specificity of human hepatic udp-glucuronosyltransferases

scientific article published on 01 January 2005

Sulfation of apomorphine by human sulfotransferases: evidence of a major role for the polymorphic phenol sulfotransferase, SULT1A1.

artículo científico publicado en 2003

Sulfotransferase activities towards xenobiotics and estradiol in two marine fish species (Mullus barbatus and Lepidorhombus boscii): characterization and inhibition by endocrine disrupters.

artículo científico publicado en 2006

Sulphation catalysed by the human cytosolic sulphotransferases--chemical defence or molecular terrorism?

artículo científico publicado en 1996

Sulphation of N-hydroxy-4-aminobiphenyl and N-hydroxy-4-acetylaminobiphenyl by human foetal and neonatal sulphotransferase

scientific article published on 01 August 1994

The Antihyperglycemic Effect of Estrone Sulfate in Genetically Obese-Diabetic (ob/ob) Mice is Associated with Reduced Hepatic Glucose-6-Phosphatase ⬇️

artículo científico publicado el 1 de diciembre de 2001

The effects of UDP-sugars, UDP and Mg2+on uridine diphosphate glucuronosyltransferase activity in human liver microsomes

artículo científico publicado en 2017

The heparan sulfate sulfotransferase 3-OST3A (HS3ST3A) is a novel tumor regulator and a prognostic marker in breast cancer

artículo científico publicado en 2016

The in vivo regulation of hepatic and renal glucose-6-phosphatase by thyroxine

artículo científico publicado en 1995

The molecular basis of the inherited deficiency of androsterone UDP-glucuronyltransferase in Wistar rats

scientific article published on 01 March 1987

The molecular biology of UDP-glucuronyltransferases

artículo científico publicado en 1987

The use of hepatocytes to investigate UDP-glucuronosyltransferases and sulfotransferases

artículo científico publicado en 2010

X-ray crystal structure of human dopamine sulfotransferase, SULT1A3. Molecular modeling and quantitative structure-activity relationship analysis demonstrate a molecular basis for sulfotransferase substrate specificity

artículo científico publicado en 1999

Lista de obras de M W Coughtrie

A Novel Method for the Immunoquantification of UDP-Glucuronosyltransferases in Human Tissue ⬇️

A case of heavy chain disease: diagnosis and monitoring using assays of immunoglobulin heavy and light chains

A general assay for UDPglucuronosyltransferase activity using polar amino-cyano stationary phase HPLC and UDP[U-14C]glucuronic acid.

A single amino acid, glu146, governs the substrate specificity of a human dopamine sulfotransferase, SULT1A3

Absolute immunoquantification of the expression of ABC transporters P-glycoprotein, breast cancer resistance protein and multidrug resistance-associated protein 2 in human liver and duodenum

Activation of benzylic alcohols to mutagens by human hepatic sulphotransferases.

Antiplatelet drug interactions.

Assessment of cryopreserved human hepatocytes as a model system to investigate sulfation and glucuronidation and to evaluate inhibitors of drug conjugation

Catecholamine Sulfation in Health and Disease

Characterization of bovine phenol sulfotransferases: evidence of a major role for SULT1B1 in the liver

Chondroitin sulfate N-acetylgalactosaminyltransferase-1 (CSGalNAcT-1) involved in chondroitin sulfate initiation: Impact of sulfation on activity and specificity.

CoMFA modeling of enzyme kinetics: K(m) values for sulfation of diverse phenolic substrates by human catecholamine sulfotransferase SULT1A3.

Common food additives are potent inhibitors of human liver 17 alpha-ethinyloestradiol and dopamine sulphotransferases

Comparison of 2-aminophenol and 4-nitrophenol as in vitro probe substrates for the major human hepatic sulfotransferase, SULT1A1, demonstrates improved selectivity with 2-aminophenol.

Conjugation of catechols by recombinant human sulfotransferases, UDP-glucuronosyltransferases, and soluble catechol O-methyltransferase: structure-conjugation relationships and predictive models.

Cytosolic phenol and steroid sulphotransferase activities are decreased in a sex-dependent manner in streptozotocin-induced diabetic rats

Dehydroepiandrosterone sulfotransferase in the developing human fetus: quantitative biochemical and immunological characterization of the hepatic, renal, and adrenal enzymes.

Design, production and characterization of antibodies discriminating between the phenol- and monoamine-sulphating forms of human phenol sulphotransferase

Differential Expression of Sulfotransferase Enzymes Involved in Thyroid Hormone Metabolism during Human Placental Development ⬇️

Differential localisation of UDP-glucuronosyltransferase in kidney during human embryonic and fetal development

Down-regulation of dehydroepiandrosterone sulfotransferase gene in human hepatocellular carcinoma

Effect of structurally diverse peroxisome proliferators on rat hepatic sulfotransferase.

Effects of hypophysectomy and thyroxine on the expression of hepatic oestrogen, hydroxysteroid and phenol sulphotransferases

Estrogen and phenol sulfotransferase activities in human fetal lung

Expression profiling of human fetal cytosolic sulfotransferases involved in steroid and thyroid hormone metabolism and in detoxification

Farnesol is glucuronidated in human liver, kidney and intestine in vitro, and is a novel substrate for UGT2B7 and UGT1A1.

Function and organization of the human cytosolic sulfotransferase (SULT) family.

Function and regulation of UDP-glucuronosyltransferase genes in health and liver disease: report of the Seventh International Workshop on Glucuronidation, September 1993, Pitlochry, Scotland.

Glucuronidation of imipramine in rabbit and human liver microsomes: assay conditions and interaction with other tertiary amine drugs

Heterogeneous expression of sulphotransferases in periportal and perivenous hepatocytes prepared from male and female rat liver.

Human Platelet Phenolsulfotransferases: cDNA Cloning, Stable Expression in V79 Cells, and Identification of a Novel Allelic Variant of the Phenol-Sulfating Form ⬇️

Human fetal adrenal hydroxysteroid sulphotransferase: cDNA cloning, stable expression in V79 cells and functional characterisation of the expressed enzyme.

Identification of a new adult human liver sulfotransferase with specificity for endogenous and xenobiotic estrogens

Immunochemical characterisation of a dehydroepiandrosterone sulfotransferase in rats and humans

Immunochemical identification of hepatic protein adducts derived from estragole.

Immunohistochemical localisation of hydroxysteroid sulphotransferase in human breast carcinoma tissue: a preliminary study

Induction of hepatic estrogen sulfotransferase expression by hypophysectomy in female rats

Influence of Morbid Obesity on the Pharmacokinetics of Morphine, Morphine-3-Glucuronide, and Morphine-6-Glucuronide

Inhibition of UDP-glucuronosyltransferase activity by possible transition-state analogues in rat-liver microsomes

Inhibition of human liver steroid sulfotransferase activities by drugs: a novel mechanism of drug toxicity?

Inhibition of thyroid hormone sulfation by hydroxylated metabolites of polychlorinated biphenyls ⬇️

Investigation of the molecular basis of the genetic deficiency of UDP-glucuronosyltransferase in Crigler-Najjar syndrome.

Liver-specific expression of paracetamol sulphotransferase

Luminal accumulation of newly synthesized morphine-3-glucuronide in rat liver microsomal vesicles

Molecular and functional characterization of microsomal UDP-glucuronic acid uptake by members of the nucleotide sugar transporter (NST) family

Molecular basis for acceptor substrate specificity of the human beta1,3-glucuronosyltransferases GlcAT-I and GlcAT-P involved in glycosaminoglycan and HNK-1 carbohydrate epitope biosynthesis, respectively

Molecular characterization of β1,4‐galactosyltransferase 7 genetic mutations linked to the progeroid form of Ehlers–Danlos syndrome (EDS) ⬇️

N-glucuronidation of carbamazepine in human tissues is mediated by UGT2B7.

Neonatal development of hepatic UGT1A9: implications of pediatric pharmacokinetics.

Ontogeny of Human Conjugating Enzymes.

Phenol sulfotransferase 1A1 activity in human liver: kinetic properties, interindividual variation and re-evaluation of the suitability of 4-nitrophenol as a probe substrate ⬇️

Phenol sulphotransferase SULT1A1*1 genotype is associated with reduced risk of colorectal cancer

Phenolsulphotransferase: localization in kidney during human embryonic and fetal development

Preparation and characterization of anti-peptide antibodies directed against human phenol and hydroxysteroid sulphotransferases

Purification and immunochemical characterization of a rat liver sulphotransferase conjugating paracetamol

Purification and properties of rat kidney UDP-glucuronosyltransferase

Quantitative evaluation of the expression and activity of five major sulfotransferases (SULTs) in human tissues: the SULT "pie".

Reduced platelet phenolsulphotransferase activity towards dopamine and 5-hydroxytryptamine in migraine

Regioselective sulfonation of dopamine by SULT1A3 in vitro provides a molecular explanation for the preponderance of dopamine-3-O-sulfate in human blood circulation

Revisiting the Latency of Uridine Diphosphate-Glucuronosyltransferases (UGTs)-How Does the Endoplasmic Reticulum Membrane Influence Their Function?

Selective induction of bilirubin UDP-glucuronosyl-transferase by perfluorodecanoic acid

Steroid sulphates inhibit the rat hepatic microsomal glucose-6-phosphatase system

Substrate specificity of human hepatic udp-glucuronosyltransferases

Sulfation of apomorphine by human sulfotransferases: evidence of a major role for the polymorphic phenol sulfotransferase, SULT1A1.

Sulfotransferase activities towards xenobiotics and estradiol in two marine fish species (Mullus barbatus and Lepidorhombus boscii): characterization and inhibition by endocrine disrupters.

Sulphation catalysed by the human cytosolic sulphotransferases--chemical defence or molecular terrorism?

Sulphation of N-hydroxy-4-aminobiphenyl and N-hydroxy-4-acetylaminobiphenyl by human foetal and neonatal sulphotransferase

The Antihyperglycemic Effect of Estrone Sulfate in Genetically Obese-Diabetic (ob/ob) Mice is Associated with Reduced Hepatic Glucose-6-Phosphatase ⬇️

The effects of UDP-sugars, UDP and Mg2+on uridine diphosphate glucuronosyltransferase activity in human liver microsomes

The heparan sulfate sulfotransferase 3-OST3A (HS3ST3A) is a novel tumor regulator and a prognostic marker in breast cancer

The in vivo regulation of hepatic and renal glucose-6-phosphatase by thyroxine

The molecular basis of the inherited deficiency of androsterone UDP-glucuronyltransferase in Wistar rats

The molecular biology of UDP-glucuronyltransferases

The use of hepatocytes to investigate UDP-glucuronosyltransferases and sulfotransferases

X-ray crystal structure of human dopamine sulfotransferase, SULT1A3. Molecular modeling and quantitative structure-activity relationship analysis demonstrate a molecular basis for sulfotransferase substrate specificity