Lista de obras - Zbigniew Leśnikowski - Dominio Público Uruguay

"Chemical ligation": a versatile method for nucleoside modification with boron clusters

artículo científico publicado en 2008

2'-deoxyadenosine bearing hydrophobic carborane pharmacophore

artículo científico publicado en 2007

A nucleoside conjugate containing a metallacarborane group and its incorporation into a DNA oligonucleotide

artículo científico publicado en 2003

Adenosine and 2'-deoxyadenosine modified with boron cluster pharmacophores as new classes of human blood platelet function modulators

artículo científico publicado en 2010

Aggregation behavior of nucleoside-boron cluster conjugates in aqueous solutions

artículo científico publicado en 2008

Anti-mycobacterial activity of thymine derivatives bearing boron clusters

artículo científico publicado en 2016

Association of TLR3 L412F Polymorphism with Cytomegalovirus Infection in Children

artículo científico publicado en 2017

Boron Clusters as a Platform for New Materials: Synthesis of Functionalized o-Carborane (C2 B10 H12 ) Derivatives Incorporating DNA Fragments

artículo científico publicado en 2015

Boron clusters as a platform for new materials: composites of nucleic acids and oligofunctionalized carboranes (C2B10H12) and their assembly into functional nanoparticles

scientific article published on 25 November 2019

Carborane-linked 2'-deoxyuridine 5'-O-triphosphate as building block for polymerase synthesis of carborane-modified DNA.

artículo científico publicado en 2017

Carboranyl oligonucleotides: 4. synthesis and physicochemical studies of oligonucleotides containing 2'-O-(o-carboran-1-yl)methyl group

artículo científico publicado en 2002

Challenges and Opportunities for the Application of Boron Clusters in Drug Design

artículo científico publicado en 2016

Comparative Study of Carborane- and Phenyl-Modified Adenosine Derivatives as Ligands for the A2A and A3 Adenosine Receptors Based on a Rigid in Silico Docking and Radioligand Replacement Assay.

artículo científico publicado en 2018

Comparative kinetic analyses of interaction of inhibitors with Rauscher murine leukemia virus and human immunodeficiency virus reverse transcriptases

artículo científico publicado en 1996

Comparative study of inorganic, boron-rich cluster and organic, phenyl adenosine modifications: synthesis and properties

artículo científico publicado en 2019

Comparative study of the effects of ortho-, meta- and para-carboranes (C2B10H12) on the physicochemical properties, cytotoxicity and antiviral activity of uridine and 2'-deoxyuridine boron cluster conjugates

scientific article published on 29 November 2019

Cytomegalovirus DNA is highly prevalent in the blood of patients with asthma and is associated with age and asthma traits

artículo científico publicado en 2017

Cytomegalovirus alpha-chemokine genotypes are associated with clinical manifestations in children with congenital or postnatal infections

artículo científico publicado en 2014

Cytomegalovirus glycoprotein H genotype distribution and the relationship with hearing loss in children

artículo científico publicado en 2014

DNA Modified with Boron⁻Metal Cluster Complexes [M(C₂B₉H)₂]-Synthesis, Properties, and Applications ⬇️

scientific article published on 07 November 2018

DNA probe modified with 3-iron bis(dicarbollide) for electrochemical determination of DNA sequence of Avian Influenza Virus H5N1.

artículo científico publicado en 2013

Decrease in 3-nitrotyrosine in the amniotic fluid of women with cytomegalovirus infection

artículo científico publicado en 2014

Detection of cytomegalovirus in human placental cells by polymerase chain reaction.

artículo científico publicado en 2006

Diastereomers of thymidine 3'-O-(methanephosphonothioate): synthesis, absolute configuration and reaction with 3'-methoxyacetylthymidine under conditions of triester approach to oligonucleotide synthesis

artículo científico publicado en 1987

Distribution of UL144, US28 and UL55 genotypes in Polish newborns with congenital cytomegalovirus infections

artículo científico publicado en 2011

Distribution of cytomegalovirus gN variants and associated clinical sequelae in infants

artículo científico publicado en 2013

Drugs against human cytomegalovirus

artículo científico publicado en 2002

EU-OPENSCREEN: A Novel Collaborative Approach to Facilitate Chemical Biology

artículo científico publicado en 2019

Effect of adenosine modified with a boron cluster pharmacophore on reactive oxygen species production by human neutrophils

scientific article published on 25 September 2012

Electrochemical DNA detection based on the polyhedral boron cluster label

artículo científico publicado en 2009

Electrochemical detection of DNA hybridization using metallacarborane unit

artículo científico publicado en 2011

High Boron-loaded DNA-Oligomers as Potential Boron Neutron Capture Therapy and Antisense Oligonucleotide Dual-Action Anticancer Agents

artículo científico publicado en 2017

Human parainfluenza virus type 3 (HPIV3) induces production of IFNγ and RANTES in human nasal epithelial cells (HNECs).

artículo científico publicado en 2015

In vitro antileukemic activity of novel adenosine derivatives bearing boron cluster modification

artículo científico publicado en 2016

Insight into the expression of RIG-I-like receptors in human third trimester placentas following ex vivo cytomegalovirus or vesicular stomatitis virus infection

scientific article published on 20 August 2020

Interactions of Boron Clusters and their Derivatives with Serum Albumin.

artículo científico publicado en 2017

Metallacarborane Complex Boosts the Rate of DNA Oligonucleotide Hydrolysis in the Reaction Catalyzed by Snake Venom Phosphodiesterase

artículo científico publicado en 2020

Mixed infections with distinct cytomegalovirus glycoprotein B genotypes in Polish pregnant women, fetuses, and newborns

artículo científico publicado en 2014

Modification of selected anti-HCMV drugs with lipophilic boron cluster modulator

artículo científico publicado el 1 de mayo de 2013

Modulation of human neutrophil activity by adenosine modified with a carborane pharmacophore

artículo científico publicado en 2014

Nucleoside modification with boron clusters and their metal complexes

artículo científico publicado en 2009

Nucleoside-metallacarborane conjugates for base-specific metal labeling of DNA

scientific article published on 01 January 2007

Octa(thymidine methanephosphonates) of partially defined stereochemistry: synthesis and effect of chirality at phosphorus on binding to pentadecadeoxyriboadenylic acid

artículo científico publicado en 1990

Oseltamivir analog with boron cluster modulator

artículo científico publicado el 1 de noviembre de 2012

P-chiral oligonucleotides. 2D Roesy NMR assignment of absolute configuration at phosphorus and conformational analysis of 5'-O-monomethoxytrityl-(2'-O-deoxyribonucleoside) 3'-O-[O-(4-nitrophenyl)]methanephosphonates

artículo científico publicado en 2002

Phosphorylation of nucleoside-metallacarborane and carborane conjugates by nucleoside kinases

artículo científico publicado en 2013

Recent developments with boron as a platform for novel drug design

artículo científico publicado en 2016

Relationship between toll-like receptor 2 Arg677Trp and Arg753Gln and toll-like receptor 4 Asp299Gly polymorphisms and cytomegalovirus infection

artículo científico publicado en 2014

Solid state, thermal synthesis of site-specific protein-boron cluster conjugates and their physicochemical and biochemical properties

artículo científico publicado en 2014

Stereoselective synthesis of P-homochiral oligo(thymidine methanephosphonates).

artículo científico publicado en 1988

Synthesis and in vitro evaluation of antiviral and cytostatic properties of novel 8-triazolyl acyclovir derivatives

scientific article published on 17 November 2018

Synthesis and the structure of 8-tetrahydrofuronium and 8-tetrahydropyronium derivatives of iron bis(dicarbollide)(-I) and their cleavage reactions

artículo científico publicado en 2015

Synthesis of lysozyme-metallacarborane conjugates and the effect of boron cluster modification on protein structure and function.

artículo científico publicado en 2015

TLR9 -1486T/C and 2848C/T SNPs Are Associated with Human Cytomegalovirus Infection in Infants

artículo científico publicado en 2016

TLR9 2848 GA heterozygotic status possibly predisposes fetuses and newborns to congenital infection with human cytomegalovirus

artículo científico publicado en 2015

Towards new boron carriers for boron neutron capture therapy: metallacarboranes and their nucleoside conjugates

artículo científico publicado en 2005

Towards new boron carriers for boron neutron capture therapy: metallacarboranes bearing cobalt, iron and chromium and their cholesterol conjugates

artículo científico publicado en 2013

Versatile Method for the Site-Specific Modification of DNA with Boron Clusters: Anti-Epidermal Growth Factor Receptor (EGFR) Antisense Oligonucleotide Case.

artículo científico publicado en 2017

What are the current challenges with the application of boron clusters to drug design?

artículo científico publicado en 2020

siRNAs modified with boron cluster and their physicochemical and biological characterization

artículo científico publicado en 2013

Lista de obras de Zbigniew Leśnikowski

"Chemical ligation": a versatile method for nucleoside modification with boron clusters

2'-deoxyadenosine bearing hydrophobic carborane pharmacophore

A nucleoside conjugate containing a metallacarborane group and its incorporation into a DNA oligonucleotide

Adenosine and 2'-deoxyadenosine modified with boron cluster pharmacophores as new classes of human blood platelet function modulators

Aggregation behavior of nucleoside-boron cluster conjugates in aqueous solutions

Anti-mycobacterial activity of thymine derivatives bearing boron clusters

Association of TLR3 L412F Polymorphism with Cytomegalovirus Infection in Children

Boron Clusters as a Platform for New Materials: Synthesis of Functionalized o-Carborane (C2 B10 H12 ) Derivatives Incorporating DNA Fragments

Boron clusters as a platform for new materials: composites of nucleic acids and oligofunctionalized carboranes (C2B10H12) and their assembly into functional nanoparticles

Carborane-linked 2'-deoxyuridine 5'-O-triphosphate as building block for polymerase synthesis of carborane-modified DNA.

Carboranyl oligonucleotides: 4. synthesis and physicochemical studies of oligonucleotides containing 2'-O-(o-carboran-1-yl)methyl group

Challenges and Opportunities for the Application of Boron Clusters in Drug Design

Comparative Study of Carborane- and Phenyl-Modified Adenosine Derivatives as Ligands for the A2A and A3 Adenosine Receptors Based on a Rigid in Silico Docking and Radioligand Replacement Assay.

Comparative kinetic analyses of interaction of inhibitors with Rauscher murine leukemia virus and human immunodeficiency virus reverse transcriptases

Comparative study of inorganic, boron-rich cluster and organic, phenyl adenosine modifications: synthesis and properties

Comparative study of the effects of ortho-, meta- and para-carboranes (C2B10H12) on the physicochemical properties, cytotoxicity and antiviral activity of uridine and 2'-deoxyuridine boron cluster conjugates

Cytomegalovirus DNA is highly prevalent in the blood of patients with asthma and is associated with age and asthma traits

Cytomegalovirus alpha-chemokine genotypes are associated with clinical manifestations in children with congenital or postnatal infections

Cytomegalovirus glycoprotein H genotype distribution and the relationship with hearing loss in children

DNA Modified with Boron⁻Metal Cluster Complexes [M(C₂B₉H)₂]-Synthesis, Properties, and Applications ⬇️

DNA probe modified with 3-iron bis(dicarbollide) for electrochemical determination of DNA sequence of Avian Influenza Virus H5N1.

Decrease in 3-nitrotyrosine in the amniotic fluid of women with cytomegalovirus infection

Detection of cytomegalovirus in human placental cells by polymerase chain reaction.

Diastereomers of thymidine 3'-O-(methanephosphonothioate): synthesis, absolute configuration and reaction with 3'-methoxyacetylthymidine under conditions of triester approach to oligonucleotide synthesis

Distribution of UL144, US28 and UL55 genotypes in Polish newborns with congenital cytomegalovirus infections

Distribution of cytomegalovirus gN variants and associated clinical sequelae in infants

Drugs against human cytomegalovirus

EU-OPENSCREEN: A Novel Collaborative Approach to Facilitate Chemical Biology

Effect of adenosine modified with a boron cluster pharmacophore on reactive oxygen species production by human neutrophils

Electrochemical DNA detection based on the polyhedral boron cluster label

Electrochemical detection of DNA hybridization using metallacarborane unit

High Boron-loaded DNA-Oligomers as Potential Boron Neutron Capture Therapy and Antisense Oligonucleotide Dual-Action Anticancer Agents

Human parainfluenza virus type 3 (HPIV3) induces production of IFNγ and RANTES in human nasal epithelial cells (HNECs).

In vitro antileukemic activity of novel adenosine derivatives bearing boron cluster modification

Insight into the expression of RIG-I-like receptors in human third trimester placentas following ex vivo cytomegalovirus or vesicular stomatitis virus infection

Interactions of Boron Clusters and their Derivatives with Serum Albumin.

Metallacarborane Complex Boosts the Rate of DNA Oligonucleotide Hydrolysis in the Reaction Catalyzed by Snake Venom Phosphodiesterase

Mixed infections with distinct cytomegalovirus glycoprotein B genotypes in Polish pregnant women, fetuses, and newborns

Modification of selected anti-HCMV drugs with lipophilic boron cluster modulator

Modulation of human neutrophil activity by adenosine modified with a carborane pharmacophore

Nucleoside modification with boron clusters and their metal complexes

Nucleoside-metallacarborane conjugates for base-specific metal labeling of DNA

Octa(thymidine methanephosphonates) of partially defined stereochemistry: synthesis and effect of chirality at phosphorus on binding to pentadecadeoxyriboadenylic acid

Oseltamivir analog with boron cluster modulator

P-chiral oligonucleotides. 2D Roesy NMR assignment of absolute configuration at phosphorus and conformational analysis of 5'-O-monomethoxytrityl-(2'-O-deoxyribonucleoside) 3'-O-[O-(4-nitrophenyl)]methanephosphonates

Phosphorylation of nucleoside-metallacarborane and carborane conjugates by nucleoside kinases

Recent developments with boron as a platform for novel drug design

Relationship between toll-like receptor 2 Arg677Trp and Arg753Gln and toll-like receptor 4 Asp299Gly polymorphisms and cytomegalovirus infection

Solid state, thermal synthesis of site-specific protein-boron cluster conjugates and their physicochemical and biochemical properties

Stereoselective synthesis of P-homochiral oligo(thymidine methanephosphonates).

Synthesis and in vitro evaluation of antiviral and cytostatic properties of novel 8-triazolyl acyclovir derivatives

Synthesis and the structure of 8-tetrahydrofuronium and 8-tetrahydropyronium derivatives of iron bis(dicarbollide)(-I) and their cleavage reactions

Synthesis of lysozyme-metallacarborane conjugates and the effect of boron cluster modification on protein structure and function.

TLR9 -1486T/C and 2848C/T SNPs Are Associated with Human Cytomegalovirus Infection in Infants

TLR9 2848 GA heterozygotic status possibly predisposes fetuses and newborns to congenital infection with human cytomegalovirus

Towards new boron carriers for boron neutron capture therapy: metallacarboranes and their nucleoside conjugates

Towards new boron carriers for boron neutron capture therapy: metallacarboranes bearing cobalt, iron and chromium and their cholesterol conjugates

Versatile Method for the Site-Specific Modification of DNA with Boron Clusters: Anti-Epidermal Growth Factor Receptor (EGFR) Antisense Oligonucleotide Case.

What are the current challenges with the application of boron clusters to drug design?

siRNAs modified with boron cluster and their physicochemical and biological characterization