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Lista de obras de J H Kordower

A confocal microscopic analysis of galaninergic hyperinnervation of cholinergic basal forebrain neurons in Alzheimer's disease

artículo científico publicado en 1997

A double-blind controlled trial of bilateral fetal nigral transplantation in Parkinson's disease

artículo científico publicado en 2003

A phase 1 clinical trial of nerve growth factor gene therapy for Alzheimer disease

artículo científico publicado en 2005

A phase1 study of stereotactic gene delivery of AAV2-NGF for Alzheimer's disease

artículo científico publicado en 2014

AAV2-Neurturin for Parkinson's Disease: What Lessons Have We Learned?

artículo científico publicado en 2016

AAV2-mediated delivery of human neurturin to the rat nigrostriatal system: long-term efficacy and tolerability of CERE-120 for Parkinson's disease

artículo científico publicado en 2007

Abnormal alpha-synuclein reduces nigral voltage-dependent anion channel 1 in sporadic and experimental Parkinson's disease

artículo científico publicado en 2014

Adrenal chromaffin cells as transplants in animal models of Parkinson's disease

artículo científico

Adrenal medullary autografts into the basal ganglia of Cebus monkeys: graft viability and fine structure

artículo científico publicado en 1988

Adrenal medullary autografts into the basal ganglia of Cebus monkeys: injury-induced regeneration.

artículo científico publicado en 1988

Adrenal medullary tissue grafting in Parkinson's disease

artículo científico publicado en 1988

Age and region-specific responses of microglia, but not astrocytes, suggest a role in selective vulnerability of dopamine neurons after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure in monkeys

artículo científico publicado en 2008

Age-Related Vulnerability of Developing Cholinergic Basal Forebrain Neurons Following Excitotoxic Lesions of the Hippocampus ⬇️

artículo científico publicado el 1 de agosto de 1994

Age-associated increases of alpha-synuclein in monkeys and humans are associated with nigrostriatal dopamine depletion: Is this the target for Parkinson's disease?

artículo científico publicado en 2006

Age-related accumulation of Marinesco bodies and lipofuscin in rhesus monkey midbrain dopamine neurons: relevance to selective neuronal vulnerability

artículo científico publicado en 2007

Age-related alterations in GABA(A) receptor subunits in the nonhuman primate hippocampus

artículo científico publicado en 2006

Age-related changes in dopamine transporters and accumulation of 3-nitrotyrosine in rhesus monkey midbrain dopamine neurons: relevance in selective neuronal vulnerability to degeneration

artículo científico publicado en 2008

Age-related changes in glial cells of dopamine midbrain subregions in rhesus monkeys

artículo científico publicado en 2008

Age-related declines in nigral neuronal function correlate with motor impairments in rhesus monkeys

artículo científico publicado en 1998

Age-related decreases in GTP-cyclohydrolase-I immunoreactive neurons in the monkey and human substantia nigra

scientific article published on 01 October 2000

Age-related decreases in Nurr1 immunoreactivity in the human substantia nigra

artículo científico publicado en 2002

Ageing as a primary risk factor for Parkinson's disease: evidence from studies of non-human primates

artículo científico publicado en 2011

Aging and Parkinson's disease: Different sides of the same coin?

artículo científico publicado en 2017

Aging-related changes in the nigrostriatal dopamine system and the response to MPTP in nonhuman primates: diminished compensatory mechanisms as a prelude to parkinsonism

artículo científico publicado en 2007

Alpha-synuclein in colonic submucosa in early untreated Parkinson's disease

artículo científico publicado en 2011

Alpha-synuclein propagation: New insights from animal models

artículo científico

Alterations in Activity-Dependent Neuroprotective Protein in Sporadic and Experimental Parkinson's Disease

artículo científico publicado en 2016

Alterations in axonal transport motor proteins in sporadic and experimental Parkinson's disease

artículo científico publicado en 2012

Alterations in lysosomal and proteasomal markers in Parkinson's disease: relationship to alpha-synuclein inclusions

artículo científico publicado en 2009

An in vivo and in vitro assessment of differentiated neuroblastoma cells as a source of donor tissue for transplantation

artículo científico publicado en 1987

Analysis of YFP(J16)-R6/2 reporter mice and postmortem brains reveals early pathology and increased vulnerability of callosal axons in Huntington's disease

artículo científico publicado en 2015

Analysis of age-related changes in psychosine metabolism in the human brain.

artículo científico publicado en 2018

Animal models of Huntington's disease

artículo científico publicado en 2007

Animal models of age- and disease-related cognitive decline: perspectives on the models and therapeutic strategies

artículo científico publicado en 1988

Animal rights terrorists: what every neuroscientist should know

artículo científico publicado en 2009

Apolipoprotein E-immunoreactivity in aged rhesus monkey cortex: colocalization with amyloid plaques

artículo científico publicado en 1994

Are growth factors the answer?

artículo científico publicado en 2009

Ascending cholinergic pathways: functional organization and implications for disease models

artículo científico publicado en 1993

Atrophy of cholinergic basal forebrain neurons following excitotoxic cortical lesions is reversed by intravenous administration of an NGF conjugate

artículo científico publicado en 1996

B2 bradykinin receptor immunoreactivity in rat brain

artículo científico publicado en 2000

Basal ganglia lesions after MPTP administration in rhesus monkeys

artículo científico publicado en 2006

Behavioral and morphological comparison of two nonhuman primate models of Huntington's disease

artículo científico publicado en 2002

Bilateral fetal nigral transplantation into the postcommissural putamen in Parkinson's disease.

artículo científico publicado en 1995

Bioactivity of AAV2‐neurturin gene therapy (CERE‐120): Differences between Parkinson's disease and nonhuman primate brains ⬇️

artículo científico publicado el 18 de noviembre de 2010

Broad distribution of ataxin 1 silencing in rhesus cerebella for spinocerebellar ataxia type 1 therapy

artículo científico publicado en 2015

Can intrabodies serve as neuroprotective therapies for Parkinson's disease? Beginning thoughts

artículo científico

Celebrating neural repair

artículo científico publicado en 2009

Cell Transplantation and Gene Therapy in Parkinson's Disease ⬇️

artículo científico publicado el 1 de enero de 2011

Cell therapy for Parkinson's disease: what next?

artículo científico

Cellular Delivery of NGF Does Not Alter the Expression of β-Amyloid Immunoreactivity in Young or Aged Nonhuman Primates ⬇️

artículo científico publicado el 1 de junio de 1997

Cellular delivery of CNTF but not NT-4/5 prevents degeneration of striatal neurons in a rodent model of Huntington's disease

artículo científico publicado en 1998

Cellular delivery of trophic factors for the treatment of Huntington's disease: is neuroprotection possible?

artículo científico publicado en 1999

Cellular delivery of trophic factors for the treatment of Huntington's disease: is neuroprotection possible?

scientific article published on 01 January 2000

Chronic ischemic stroke model in cynomolgus monkeys: behavioral, neuroimaging and anatomical study

artículo científico publicado en 2003

Chronic stress-induced gut dysfunction exacerbates Parkinson's disease phenotype and pathology in a rotenone-induced mouse model of Parkinson's disease

artículo científico publicado en 2018

Circuit-specific alterations of N-methyl-D-aspartate receptor subunit 1 in the dentate gyrus of aged monkeys

artículo científico publicado en 1996

Clinical pattern and risk factors for dyskinesias following fetal nigral transplantation in Parkinson's disease: a double blind video-based analysis

artículo científico publicado en 2009

Clinicopathological findings following intraventricular glial-derived neurotrophic factor treatment in a patient with Parkinson's disease

artículo científico publicado en 1999

Cografts of adrenal medulla with C6 glioma cells in rats with 6-hydroxydopamine-induced lesions.

artículo científico publicado en 1990

Connections of the hippocampal formation in humans: II. The endfolial fiber pathway ⬇️

artículo científico publicado el 1 de septiembre de 1997

Continuous DOPA synthesis from a single AAV: dosing and efficacy in models of Parkinson's disease

artículo científico publicado en 2013

Corrigendum to: In Utero Exposure to Anesthetics Alters Neuronal Migration Pattern in Developing Cerebral Cortex and Causes Postnatal Behavioral Deficits in Rats

scientific article published on 22 June 2020

Cortical ablation induces a spreading calcium-dependent, secondary pathogenesis which can be reduced by inhibiting calpain

artículo científico publicado en 1999

Cryopreservation Maintains Functionality of Human iPSC Dopamine Neurons and Rescues Parkinsonian Phenotypes In Vivo.

artículo científico publicado en 2017

Cyclosporin A protects striatal neurons in vitro and in vivo from 3-nitropropionic acid toxicity.

artículo científico publicado en 2000

Decreased alpha-synuclein expression in the aging mouse substantia nigra

artículo científico publicado en 2009

Decreased trkA gene expression within basal forebrain neurons in Alzheimer's disease.

artículo científico publicado en 1996

Deep brain stimulation for treatment of obesity in rats

scientific article published on 01 October 2007

Delayed onset of progressive dystonia following subacute 3-nitropropionic acid treatment in Cebus apella monkeys

artículo científico publicado en 2000

Delivery of neurotrophic factors to the CNS using encapsulated cells: developing treatments for neurodegenerative diseases.

artículo científico publicado en 1995

Delivery of neurturin by AAV2 (CERE-120)-mediated gene transfer provides structural and functional neuroprotection and neurorestoration in MPTP-treated monkeys

artículo científico publicado en 2006

Delivery of therapeutic molecules into the CNS.

artículo científico publicado en 2000

Delivery of trophic factors to the primate brain

artículo científico publicado en 1993

Demonstration of prion-like properties of mutant huntingtin fibrils in both in vitro and in vivo paradigms

scientific article published on 20 February 2019

Detecting Alpha Synuclein Seeding Activity in Formaldehyde-Fixed MSA Patient Tissue by PMCA.

artículo científico publicado en 2018

Differential transduction following basal ganglia administration of distinct pseudotyped AAV capsid serotypes in nonhuman primates

artículo científico publicado en 2009

Differential vulnerability of neurons in Huntington's disease: the role of cell type-specific features

artículo científico publicado en 2010

Disease Modification Through Trophic Factor Delivery

artículo científico publicado en 2018

Disease duration and the integrity of the nigrostriatal system in Parkinson's disease

scientific article published on August 2013

Disease modification and biomarker development in Parkinson disease: Revision or reconstruction?

artículo científico publicado en 2020

Dissociation of galaninergic and neurotrophic plasticity in Down syndrome and Alzheimer disease

artículo científico publicado en 1995

Dissociation of p75 receptors and nerve growth factor neurotrophic effects: lack of p75 immunoreactivity in striatum following physical trauma, excitotoxicity and NGF administration

artículo científico publicado en 1996

Distribution of high affinity choline transporter immunoreactivity in the primate central nervous system

artículo científico publicado en 2003

Do subjects with minimal motor features have prodromal PD?

artículo científico publicado en 2018

Does Developmental Variability in the Number of Midbrain Dopamine Neurons Affect Individual Risk for Sporadic Parkinson's Disease?

artículo científico publicado en 2020

Dopamine D2 receptor mRNA is expressed in maturing neurons of the human hippocampal and subicular fields

artículo científico publicado en 1997

Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's disease

artículo científico publicado en 2011

Dopamine transporter-immunoreactive neurons decrease with age in the human substantia nigra

artículo científico publicado en 1999

Dopaminergic transplantation for Parkinson's disease: current status and future prospects

artículo científico publicado en 2009

Dopaminergic transplants in patients with Parkinson's disease: neuroanatomical correlates of clinical recovery

artículo científico publicado en 1997

Doublecortin expression in adult cat and primate cerebral cortex relates to immature neurons that develop into GABAergic subgroups

artículo científico publicado en 2008

Doublecortin-expressing cells persist in the associative cerebral cortex and amygdala in aged nonhuman primates

scientific article published on 13 October 2009

Down-regulation of trkA mRNA within nucleus basalis neurons in individuals with mild cognitive impairment and Alzheimer's disease

artículo científico publicado en 2001

Early changes in Huntington's disease patient brains involve alterations in cytoskeletal and synaptic elements

artículo científico publicado en 2004

Early degenerative changes in transgenic mice expressing mutant huntingtin involve dendritic abnormalities but no impairment of mitochondrial energy production

artículo científico publicado en 2001

Effect of Stereotaxic Intrastriatal Cografts of Autologous Adrenal Medulla and Peripheral Nerve in Parkinson's Disease: Two-Year Follow-up Study ⬇️

artículo científico publicado el 1 de octubre de 1997

Effects of estrogen replacement therapy on cholinergic basal forebrain neurons and cortical cholinergic innervation in young and aged ovariectomized rhesus monkeys

artículo científico publicado en 2004

Encapsulated PC12 cell transplants into hemiparkinsonian monkeys: a behavioral, neuroanatomical, and neurochemical analysis

artículo científico publicado en 1995

Endocytic vesicle rupture is a conserved mechanism of cellular invasion by amyloid proteins

artículo científico publicado en 2017

Endogenous alpha-synuclein monomers, oligomers and resulting pathology: let's talk about the lipids in the room

artículo científico publicado en 2019

Enduring cortical alterations after a single in-vivo treatment of HIV-1 Tat.

artículo científico publicado en 2012

Entorhinal cortex beta-amyloid load in individuals with mild cognitive impairment

artículo científico publicado en 1999

Estrogen increases the number of spinophilin-immunoreactive spines in the hippocampus of young and aged female rhesus monkeys

artículo científico publicado en 2003

Estrogen receptor alpha containing neurons in the monkey forebrain: lack of association with calcium binding proteins and choline acetyltransferase

artículo científico publicado en 2004

Estrogen receptor immunoreactivity within subregions of the rat forebrain: neuronal distribution and association with perikarya containing choline acetyltransferase

artículo científico publicado en 1999

Estrogen replacement increases spinophilin-immunoreactive spine number in the prefrontal cortex of female rhesus monkeys

artículo científico publicado en 2004

Etiology of Parkinson's disease: Genetics and environment revisited

artículo científico publicado en 2002

Evaluation of alpha-synuclein immunohistochemical methods for the detection of Lewy-type synucleinopathy in gastrointestinal biopsies

artículo científico publicado en 2016

Evidence that Cereport's ability to increase permeability of rat gliomas is dependent upon extent of tumor growth: implications for treating newly emerging tumor colonies

artículo científico publicado en 2000

Excitotoxic and metabolic damage to the rodent striatum: role of the P75 neurotrophin receptor and glial progenitors

artículo científico publicado en 2002

Expression, bioactivity, and safety 1 year after adeno-associated viral vector type 2-mediated delivery of neurturin to the monkey nigrostriatal system support cere-120 for Parkinson's disease

artículo científico publicado en 2009

Extensive neuroprotection by choroid plexus transplants in excitotoxin lesioned monkeys

artículo científico publicado en 2006

Failure of proteasome inhibitor administration to provide a model of Parkinson's disease in rats and monkeys

artículo científico publicado en 2006

Fetal grafting for Parkinson's disease: expression of immune markers in two patients with functional fetal nigral implants

artículo científico publicado en 1997

Fetal grafts for Parkinson's disease: Decades in the making

artículo científico publicado en 2016

Fetal nigral grafts survive and mediate clinical benefit in a patient with Parkinson's disease

artículo científico publicado en 1998

Fetal nigral transplantation as a therapy for Parkinson's disease

artículo científico publicado en 1996

Focal not widespread grafts induce novel dyskinetic behavior in parkinsonian rats

artículo científico publicado en 2005

Functional fetal nigral grafts in a patient with Parkinson's disease: chemoanatomic, ultrastructural, and metabolic studies

artículo científico publicado en 1996

Future of cell and gene therapies for Parkinson's disease

artículo científico publicado en 2008

GDNF and Parkinson's Disease: Where Next? A Summary from a Recent Workshop

artículo científico publicado en 2020

GDNF family ligands: a potential future for Parkinson's disease therapy

artículo científico publicado en 2011

GFAP knockout mice have increased levels of GDNF that protect striatal neurons from metabolic and excitotoxic insults ⬇️

artículo científico publicado el 30 de junio de 2003

Galanin expression within the basal forebrain in Alzheimer's disease. Comments on therapeutic potential

artículo científico publicado en 1998

Galanin immunoreactivity in the primate central nervous system

artículo científico publicado el 22 de mayo de 1992

Galanin immunoreactivity within the primate basal forebrain: evolutionary change between monkeys and apes.

artículo científico publicado en 1993

Galanin-like immunoreactivity within the primate basal forebrain: differential staining patterns between humans and monkeys

artículo científico publicado en 1990

Galaninergic innervation of the cholinergic vertical limb of the diagonal band (Ch2) and bed nucleus of the stria terminalis in aging, Alzheimer's disease and Down's syndrome.

artículo científico publicado en 1993

Gene delivery of AAV2-neurturin for Parkinson's disease: a double-blind, randomised, controlled trial

artículo científico publicado en 2010

Gene delivery of neurturin to putamen and substantia nigra in Parkinson disease: A double-blind, randomized, controlled trial

artículo científico publicado en 2015

Gene therapy approaches for the treatment of Parkinson's disease

artículo científico publicado en 2007

Gene therapy for Huntington's disease

artículo científico

Gene therapy for Parkinson's disease

scientific article published on 01 January 2010

Gene therapy for Parkinson's disease: still a hot topic?

artículo científico publicado en 2015

Gene therapy to the rescue in Parkinson's disease. Response from Kordower and Aebischer

artículo científico publicado en 2001

Gene transfer of trophic factors and stem cell grafting as treatments for Parkinson's disease

artículo científico publicado en 2006

Gene transfer provides a practical means for safe, long-term, targeted delivery of biologically active neurotrophic factor proteins for neurodegenerative diseases

artículo científico publicado en 2011

Generation and transplantation of EGF-responsive neural stem cells derived from GFAP-hNGF transgenic mice.

artículo científico publicado en 1997

Grafts of EGF-responsive neural stem cells derived from GFAP-hNGF transgenic mice: trophic and tropic effects in a rodent model of Huntington's disease.

artículo científico publicado en 1997

How strong is the evidence that Parkinson's disease is a prion disorder?

artículo científico publicado en 2016

Human neural progenitors deliver glial cell line-derived neurotrophic factor to parkinsonian rodents and aged primates

artículo científico publicado en 2006

Human neural stem cell transplants improve motor function in a rat model of Huntington's disease

artículo científico publicado en 2004

Huntington's disease: pathological mechanisms and therapeutic strategies

artículo científico publicado en 2007

Immunotherapy in Parkinson's disease: Current status and future directions

scientific article published on 25 August 2019

Implants of encapsulated human CNTF-producing fibroblasts prevent behavioral deficits and striatal degeneration in a rodent model of Huntington's disease

artículo científico publicado en 1996

Implants of polymer-encapsulated human NGF-secreting cells in the nonhuman primate: rescue and sprouting of degenerating cholinergic basal forebrain neurons

artículo científico publicado en 1994

In memorium: Roy A.E. Bakay, MD.

artículo científico publicado en 2013

In utero Exposure to Anesthetics Alters Neuronal Migration Pattern in Developing Cerebral Cortex and Causes Postnatal Behavioral Deficits in Rats

artículo científico publicado en 2019

In vivo evaluation of [(123)I]MNI-420: a novel single photon emission computed tomography radiotracer for imaging of adenosine 2A receptors in brain

artículo científico publicado en 2013

In vivo gene delivery of glial cell line--derived neurotrophic factor for Parkinson's disease

artículo científico publicado en 2003

Increased intestinal permeability correlates with sigmoid mucosa alpha-synuclein staining and endotoxin exposure markers in early Parkinson's disease

artículo científico publicado en 2011

Induction of alpha-synuclein pathology in the enteric nervous system of the rat and non-human primate results in gastrointestinal dysmotility and transient CNS pathology

artículo científico publicado en 2018

Inflammation in Experimental Models of α-Synucleinopathies

scientific article published on 03 October 2020

Influence of Donor Age on the Survival of Human Embryonic Dopaminergic Neural Grafts

artículo científico publicado en 1992

Influence of cell preparation and target location on the behavioral recovery after striatal transplantation of fetal dopaminergic neurons in a primate model of Parkinson's disease

artículo científico publicado en 2007

Inhibitors of cyclooxygenase-2, but not cyclooxygenase-1 provide structural and functional protection against quinolinic acid-induced neurodegeneration

artículo científico publicado en 2003

Injectable hydrogels providing sustained delivery of vascular endothelial growth factor are neuroprotective in a rat model of Huntington's disease

artículo científico publicado en 2009

Intrastriatal CERE-120 (AAV-Neurturin) protects striatal and cortical neurons and delays motor deficits in a transgenic mouse model of Huntington's disease

artículo científico publicado en 2008

Intrastriatal Infusions of Brain-Derived Neurotrophic Factor: Retrograde Transport and Colocalization with Dopamine Containing Substantia Nigra Neurons in Rat ⬇️

artículo científico publicado el 1 de septiembre de 1994

Intrastriatal alpha-synuclein fibrils in monkeys: spreading, imaging and neuropathological changes

scientific article published on 01 November 2019

Intrastriatal and intraventricular infusion of brain-derived neurotrophic factor in the cynomologous monkey: distribution, retrograde transport and co-localization with substantia nigra dopamine-containing neurons

artículo científico publicado en 1996

Intrastriatal implants of polymer encapsulated cells genetically modified to secrete human nerve growth factor: trophic effects upon cholinergic and noncholinergic striatal neurons

artículo científico publicado en 1996

Intravenous administration of a transferrin receptor antibody-nerve growth factor conjugate prevents the degeneration of cholinergic striatal neurons in a model of Huntington disease

artículo científico publicado en 1994

Introduction: gene therapy has gone from a pipe dream to clinical reality

artículo científico publicado en 2012

Is Axonal Degeneration a Key Early Event in Parkinson's Disease?

artículo científico publicado en 2016

Is alpha-synuclein in the colon a biomarker for premotor Parkinson's disease? Evidence from 3 cases

artículo científico publicado en 2012

Issues regarding gene therapy products for Parkinson's disease: the development of CERE-120 (AAV-NTN) as one reference point

artículo científico publicado en 2007

Kinetic modeling and occupancy measures of the norepinephrine transporters in baboons using single photon emission computed tomography with (123)I-INER.

artículo científico publicado en 2012

Knockout of p75NTR does not alter the viability of striatal neurons following a metabolic or excitotoxic injury

artículo científico publicado en 2003

Lentiviral gene transfer to the nonhuman primate brain

artículo científico publicado en 1999

Lentivirally delivered glial cell line-derived neurotrophic factor increases the number of striatal dopaminergic neurons in primate models of nigrostriatal degeneration.

artículo científico publicado en 2002

Lewy body pathology in fetal grafts

artículo científico publicado en 2010

Lewy body pathology in long-term fetal nigral transplants: is Parkinson's disease transmitted from one neural system to another?

scientific article published on 01 January 2009

Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease

artículo científico publicado en 2008

Long-term evaluation of bilateral fetal nigral transplantation in Parkinson disease

artículo científico publicado en 1999

Long-term gonadal hormone treatment and endogenous neurogenesis in the dentate gyrus of the adult female monkey

artículo científico publicado en 2010

Long-term post-mortem studies following neurturin gene therapy in patients with advanced Parkinson's disease

artículo científico publicado en 2020

Loss and atrophy of layer II entorhinal cortex neurons in elderly people with mild cognitive impairment

artículo científico publicado en 2001

Loss of One Engrailed1 Allele Enhances Induced α-Synucleinopathy

scientific article published on 01 January 2019

Loss of basal forebrain P75(NTR) immunoreactivity in subjects with mild cognitive impairment and Alzheimer's disease

artículo científico publicado en 2002

Loss of developing cholinergic basal forebrain neurons following excitotoxic lesions of the hippocampus: rescue by neurotrophins

artículo científico publicado en 1994

Loss of nerve growth factor receptor-containing neurons in Alzheimer's disease: a quantitative analysis across subregions of the basal forebrain

artículo científico publicado en 1989

Loss of nucleus basalis neurons containing trkA immunoreactivity in individuals with mild cognitive impairment and early Alzheimer's disease

artículo científico publicado en 2000

Mechanisms for cell-to-cell propagation no longer lag behind

artículo científico publicado en 2016

Misfolded proteins in Huntington disease fetal grafts: further evidence of cell-to-cell transfer?

artículo científico publicado en 2014

Missing pieces in the Parkinson's disease puzzle

artículo científico publicado en 2010

Mitochondrial pyruvate carrier regulates autophagy, inflammation, and neurodegeneration in experimental models of Parkinson's disease

artículo científico publicado en 2016

Mitomycin-C treatment during differentiation of induced pluripotent stem cell-derived dopamine neurons reduces proliferation without compromising survival or function in vivo

artículo científico publicado en 2020

Modeling Parkinson's disease

artículo científico publicado en 2009

Multicenter Assessment of Immunohistochemical Methods for Pathological Alpha-Synuclein in Sigmoid Colon of Autopsied Parkinson's Disease and Control Subjects

artículo científico publicado en 2016

NGF and Alzheimer's disease: unfulfilled promise and untapped potential

artículo científico publicado en 1989

NGF receptor (p75)-immunoreactivity in the developing primate basal ganglia

artículo científico publicado en 1993

NGF-like trophic support from peripheral nerve for grafted rhesus adrenal chromaffin cells

artículo científico publicado en 1990

Neonatal immune-tolerance in mice does not prevent xenograft rejection

artículo científico publicado en 2014

Nerve growth factor in Alzheimerʼs disease: defective retrograde transport to nucleus basalis ⬇️

artículo científico publicado el 9 de mayo de 1995

Nerve growth factor receptor and choline acetyltransferase remain colocalized in the nucleus basalis (Ch4) of Alzheimer's patients

artículo científico publicado en 1989

Nerve growth factor receptor expressing human basal forebrain neurons: pathologic alterations in Alzheimer's and Parkinson's disease

artículo científico publicado en 1989

Nerve growth factor receptor immunoreactive profiles in the normal, aged human basal forebrain: colocalization with cholinergic neurons

artículo científico publicado en 1989

Nerve growth factor receptor immunoreactivity in the new world monkey (Cebus apella) and human cerebellum

artículo científico publicado en 1991

Nerve growth factor receptor immunoreactivity in the nonhuman primate (Cebus apella): distribution, morphology, and colocalization with cholinergic enzymes

artículo científico publicado en 1988

Nerve growth factor receptor-immunoreactive neurons within the developing human cortex

artículo científico publicado en 1992

Nerve growth factor-like immunoreactive profiles in the primate basal forebrain and hippocampal formation

artículo científico publicado en 1994

Neural repair strategies for Parkinson's disease: insights from primate models

artículo científico publicado en 2006

Neural transplantation as a therapy for Parkinson's disease

artículo científico publicado el 1 de enero de 1997

Neural transplants in patients with Huntington's disease undergo disease-like neuronal degeneration

artículo científico publicado en 2009

Neuroblastoma cells in neural transplants: a neuroanatomical and behavioral analysis

artículo científico publicado en 1987

Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease

artículo científico publicado en 2000

Neuropathological evidence of graft survival and striatal reinnervation after the transplantation of fetal mesencephalic tissue in a patient with Parkinson's disease

artículo científico publicado en 1995

Neuropathological study 16 years after autologous adrenal medullary transplantation in a Parkinson's disease patient

artículo científico publicado en 2007

Neuropathology in transplants in Parkinson's disease: implications for disease pathogenesis and the future of cell therapy

artículo científico publicado en 2012

Neuropathology of fetal nigra transplants for Parkinson's disease

artículo científico publicado en 2000

Neuropathology of fetal nigral grafts in patients with Parkinson's disease.

artículo científico publicado en 1998

Neuroprotection for Parkinson's disease using viral vector-mediated delivery of GDNF.

artículo científico publicado en 2002

Neurotrophic factor therapy for Parkinson’s disease

artículo científico publicado el 1 de enero de 2010

Neurturin gene therapy improves motor function and prevents death of striatal neurons in a 3-nitropropionic acid rat model of Huntington's disease

artículo científico publicado en 2007

Neutralization of RANTES and Eotaxin Prevents the Loss of Dopaminergic Neurons in a Mouse Model of Parkinson Disease

artículo científico publicado en 2016

Novel oligodendroglial alpha synuclein viral vector models of multiple system atrophy: studies in rodents and nonhuman primates

artículo científico publicado en 2017

Nurr1 in Parkinson's disease and related disorders

artículo científico publicado en 2006

Ontogeny of the dopamine D2 receptor mRNA expressing cells in the human hippocampal formation and temporal neocortex

artículo científico publicado en 2000

Optimizing maturity and dose of iPSC-derived dopamine progenitor cell therapy for Parkinson's disease

artículo científico publicado en 2022

PGC-1α Promoter Methylation in Parkinson's Disease

artículo científico publicado en 2015

Parkinson's disease and prion disease: Straining the comparison

artículo científico publicado en 2015

Parkinsonian monkeys with prior levodopa-induced dyskinesias followed by fetal dopamine precursor grafts do not display graft-induced dyskinesias

artículo científico publicado en 2016

Past, present, and future of Parkinson's disease: A special essay on the 200th Anniversary of the Shaking Palsy

artículo científico publicado en 2017

Peripheral alpha-synuclein and Parkinson's disease

artículo científico publicado en 2014

Post-mortem assessment of the short and long-term effects of the trophic factor neurturin in patients with α-synucleinopathies

artículo científico publicado en 2015

Postmortem study of deep brain stimulation of the anterior thalamus: case report

artículo científico publicado en 2008

Prenatal 3,4-methylenedioxymethamphetamine (ecstasy) alters exploratory behavior, reduces monoamine metabolism, and increases forebrain tyrosine hydroxylase fiber density of juvenile rats

artículo científico publicado en 2003

Prenatal exposure to MDMA alters noradrenergic neurodevelopment in the rat.

artículo científico publicado en 2011

Presence of tau pathology within foetal neural allografts in patients with Huntington's and Parkinson's disease

artículo científico publicado en 2017

Primate models of Parkinson's disease ⬇️

artículo científico publicado el 1 de octubre de 2003

Probing the striatal dopamine system for a putative neuroprotective effect of deep brain stimulation in Parkinson's disease

artículo científico publicado en 2018

Progression of intestinal permeability changes and alpha-synuclein expression in a mouse model of Parkinson's disease.

artículo científico publicado en 2013

Propagation of host disease to grafted neurons: accumulating evidence

artículo científico publicado en 2009

Properly scaled and targeted AAV2-NRTN (neurturin) to the substantia nigra is safe, effective and causes no weight loss: support for nigral targeting in Parkinson's disease

artículo científico publicado en 2011

Proteasome inhibition and Parkinson's disease modeling

artículo científico publicado en 2006

Proteasome-targeted nanobodies alleviate pathology and functional decline in an α-synuclein-based Parkinson's disease model

scholarly article by Diptaman Chatterjee et al published 2018 in NPJ Parkinson's disease

Protective effect of encapsulated cells producing neurotrophic factor CNTF in a monkey model of Huntington's disease

artículo científico publicado en 1997

Putative chromaffin cell survival and enhanced host-derived TH-Fiber innervation following a functional adrenal medulla autograft for Parkinson's disease ⬇️

artículo científico publicado el 1 de abril de 1991

RET expression does not change with age in the substantia nigra pars compacta of rhesus monkeys

artículo científico publicado en 2005

RNA amplification of bromodeoxyuridine labeled newborn neurons in the monkey hippocampus

artículo científico publicado en 2004

Reduction in TrkA-immunoreactive neurons is not associated with an overexpression of galaninergic fibers within the nucleus basalis in Down's syndrome

artículo científico publicado en 2000

Reduction in p140-TrkA Receptor Protein within the Nucleus Basalis and Cortex in Alzheimer's Disease ⬇️

artículo científico publicado el 1 de julio de 1997

Regulatable promoters and gene therapy for Parkinson's disease: is the only thing to fear, fear itself?

artículo científico publicado en 2007

Regulation of cyclic AMP response element binding and hippocampal plasticity-related genes by peroxisome proliferator-activated receptor α.

artículo científico publicado en 2013

Reply to: “Being too inclusive about synuclein inclusions”

Response of the monkey cholinergic septohippocampal system to fornix transection: a histochemical and cytochemical analysis

artículo científico publicado en 1990

Robust graft survival and normalized dopaminergic innervation do not obligate recovery in a Parkinson disease patient

artículo científico publicado en 2017

Role of TLR4 in the gut-brain axis in Parkinson's disease: a translational study from men to mice

artículo científico publicado en 2018

Role of heparin binding growth factors in nigrostriatal dopamine system development and Parkinson's disease

artículo científico publicado en 2007

Selective inhibition of NF-kappaB activation prevents dopaminergic neuronal loss in a mouse model of Parkinson's disease

artículo científico publicado en 2007

Special issue on stem cells

artículo científico publicado en 2014

Spreading of alpha-synuclein - relevant or epiphenomenon?

scientific article published on 09 July 2019

Striatal Nurr1 Facilitates the Dyskinetic State and Exacerbates Levodopa-Induced Dyskinesia in a Rat Model of Parkinson's Disease

artículo científico publicado en 2020

Striatal adrenal medulla/sural nerve cografts in hemiparkinsonian monkeys

artículo científico publicado en 1990

Striatal delivery of CERE-120, an AAV2 vector encoding human neurturin, enhances activity of the dopaminergic nigrostriatal system in aged monkeys

artículo científico publicado en 2007

Striatal trophic factor activity in aging monkeys with unilateral MPTP-induced parkinsonism.

artículo científico publicado en 2005

Structural and functional neuroprotection in a rat model of Huntington's disease by viral gene transfer of GDNF.

artículo científico publicado en 2003

Substantia nigra tangles are related to gait impairment in older persons

artículo científico publicado en 2006

Survival and early differentiation of human neural stem cells transplanted in a nonhuman primate model of stroke

artículo científico publicado en 2006

Systemic administration of the immunophilin ligand GPI 1046 in MPTP-treated monkeys

artículo científico publicado en 2001

T cell infiltration in both human multiple system atrophy and a novel mouse model of the disease

artículo científico publicado en 2020

TDP-43 Proteinopathy: Aggregation and Propagation in the Pathogenesis of Amyotrophic Lateral Sclerosis

artículo científico publicado en 2016

TRK and p75 neurotrophin receptor systems in the developing human brain

scientific article published on 01 June 1996

Targeting α-Synuclein as a therapy for Parkinson's disease: The battle begins.

artículo científico publicado en 2017

Telencephalic cholinergic system of the New World monkey (Cebus apella): morphological and cytoarchitectonic assessment and analysis of the projection to the amygdala

artículo científico publicado en 1989

Temporal evolution of microglia and α-synuclein accumulation following foetal grafting in Parkinson's disease

scientific article published on 01 June 2019

Testing NF-κB-based therapy in hemiparkinsonian monkeys

artículo científico publicado en 2012

The Potential Role of Gut-Derived Inflammation in Multiple System Atrophy.

artículo científico publicado en 2017

The Search for a Peripheral Biopsy Indicator of α-Synuclein Pathology for Parkinson Disease

artículo científico publicado en 2017

The aged monkey basal forebrain: rescue and sprouting of axotomized basal forebrain neurons after grafts of encapsulated cells secreting human nerve growth factor

artículo científico publicado en 1994

The first miracle in neurodegenerative disease: the discovery of oral levodopa

artículo científico publicado en 1999

The immunophilin ligand GPI-1046 does not have neuroregenerative effects in MPTP-treated monkeys

artículo científico publicado en 2002

The influence of donor age on the survival of solid and suspension intraparenchymal human embryonic nigral grafts.

artículo científico publicado en 1995

The native form of α-Synuclein: Monomer, tetramer, or a combination in equilibrium

artículo científico

The prion hypothesis of Parkinson's disease

artículo científico

The role of alpha-synuclein in Parkinson's disease: insights from animal models

artículo científico publicado en 2003

Therapeutic approaches to target alpha-synuclein pathology

artículo científico publicado en 2017

Transfer of host-derived α synuclein to grafted dopaminergic neurons in rat

artículo científico publicado en 2011

Transgene expression, bioactivity, and safety of CERE-120 (AAV2-neurturin) following delivery to the monkey striatum

artículo científico publicado en 2008

Transplanted dopaminergic neurons develop PD pathologic changes: a second case report

artículo científico publicado en 2008

Transplanted fetal striatum in Huntington's disease: phenotypic development and lack of pathology

artículo científico publicado en 2000

Treatment with fetal allografts

artículo científico publicado en 1997

TrkA-immunoreactive profiles in the central nervous system: colocalization with neurons containing p75 nerve growth factor receptor, choline acetyltransferase, and serotonin

artículo científico publicado en 1994

Trophic factor gene therapy for Parkinson's disease

artículo científico

Trophic factors for Parkinson's disease: To live or let die.

artículo científico publicado en 2015

Trophic factors therapy in Parkinson's disease

artículo científico publicado en 2009

Tyrosine hydroxylase-immunoreactive somata within the primate subfornical organ: species specificity

scientific article published on 01 October 1988

Upregulation of choline acetyltransferase activity in hippocampus and frontal cortex of elderly subjects with mild cognitive impairment.

artículo científico publicado en 2002

Viral delivery of glial cell line-derived neurotrophic factor improves behavior and protects striatal neurons in a mouse model of Huntington's disease

artículo científico publicado en 2006

Viral vector-mediated gene therapy for Parkinson's disease

article

Viral-based rodent and nonhuman primate models of multiple system atrophy: Fidelity to the human disease

artículo científico publicado en 2020

Widespread Striatal Delivery of GDNF from Encapsulated Cells Prevents the Anatomical and Functional Consequences of Excitotoxicity

scientific article published on 11 March 2019

Xenogeneic adrenal medulla graft rejection rather than survival leads to increased rat striatal tyrosine hydroxylase immunoreactivity

artículo científico publicado en 1997

p75 nerve growth factor receptor immunoreactivity in the human brainstem and spinal cord

artículo científico publicado en 1992

trk-immunoreactivity in the monkey central nervous system: forebrain

artículo científico publicado en 1994

α-Synuclein nonhuman primate models of Parkinson's disease

artículo científico publicado en 2017

α-synuclein aggregation reduces nigral myocyte enhancer Factor-2D in idiopathic and experimental Parkinson's disease ⬇️

artículo científico publicado el 9 de septiembre de 2010

β-Secretase-1 elevation in aged monkey and Alzheimer's disease human cerebral cortex occurs around the vasculature in partnership with multisystem axon terminal pathogenesis and β-amyloid accumulation

artículo científico publicado en 2010

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