Lista de obras -

4th European Seminars in Virology on Oncogenic and Oncolytic Viruses, in Bertinoro (Bologna), Italy.

artículo científico publicado en 2016

A 6-aminoquinolone compound, WC5, with potent and selective anti-human cytomegalovirus activity

artículo científico publicado en 2008

A Broad Anti-influenza Hybrid Small Molecule That Potently Disrupts the Interaction of Polymerase Acidic Protein-Basic Protein 1 (PA-PB1) Subunits

artículo científico publicado en 2015

A point mutation in a herpesvirus polymerase determines neuropathogenicity

artículo científico publicado en 2007

A quantitative LumiFluo assay to test inhibitory compounds blocking p53 degradation induced by human papillomavirus oncoprotein E6 in living cells

artículo científico publicado en 2018

Analysis of the association of the human cytomegalovirus DNA polymerase subunit UL44 with the viral DNA replication factor UL84.

artículo científico publicado en 2009

Antiviral properties of new arylsulfone derivatives with activity against human betaherpesviruses

artículo científico publicado en 2006

Antiviral strategies against influenza virus: towards new therapeutic approaches

artículo científico publicado en 2014

Approaches for the generation of new anti-cytomegalovirus agents: identification of protein-protein interaction inhibitors and compounds against the HCMV IE2 protein

artículo científico publicado en 2014

Binding parameters and thermodynamics of the interaction of the human cytomegalovirus DNA polymerase accessory protein, UL44, with DNA: implications for the processivity mechanism

artículo científico publicado en 2007

Cloning, expression, and functional characterization of the equine herpesvirus 1 DNA polymerase and its accessory subunit

artículo científico publicado en 2006

Daclatasvir plasma level and resistance selection in HIV patients with hepatitis C virus cirrhosis treated with daclatasvir, sofosbuvir, and ribavirin

artículo científico publicado en 2016

Design, synthesis, and evaluation of WC5 analogues as inhibitors of human cytomegalovirus Immediate-Early 2 protein, a promising target for anti-HCMV treatment

artículo científico publicado en 2013

Development and validation of a simple and robust HPLC method with UV detection for quantification of the hepatitis C virus inhibitor daclatasvir in human plasma

artículo científico publicado en 2016

Development of a simple HPLC-UV method for the determination of the hepatitis C virus inhibitor simeprevir in human plasma

artículo científico publicado en 2016

Disruption of protein-protein interactions: towards new targets for chemotherapy

artículo científico publicado en 2005

Drug Repurposing Approach Identifies Inhibitors of the Prototypic Viral Transcription Factor IE2 that Block Human Cytomegalovirus Replication

artículo científico publicado en 2016

Drug Repurposing Campaigns for Human Cytomegalovirus Identify a Natural Compound Targeting the Immediate-Early 2 (IE2) Protein: A Comment on "The Natural Flavonoid Compound Deguelin Inhibits HCMV Lytic Replication within Fibroblasts"

artículo científico publicado en 2019

Drug Repurposing for Viral Infectious Diseases: How Far Are We?

scientific article published on 11 May 2018

Early inhibitors of human cytomegalovirus: state-of-art and therapeutic perspectives

scientific article published on 28 April 2011

Effects of hepatitis C virus infection on the pharmacokinetics of ritonavir-boosted atazanavir in HIV-1-infected patients

artículo científico publicado en 2012

Efficient and regioselective one-step synthesis of 7-aryl-5-methyl- and 5-aryl-7-methyl-2-amino-[1,2,4]triazolo[1,5-a]pyrimidine derivatives

artículo científico publicado en 2017

HPV16 E6 and E7 upregulate the histone lysine demethylase KDM2B through the c-MYC/miR-146a-5p axys

artículo científico publicado en 2018

Human cytomegalovirus DNA replication: antiviral targets and drugs

artículo científico publicado en 2008

Human cytomegalovirus inhibitor AL18 also possesses activity against influenza A and B viruses

artículo científico publicado en 2012

Inhibition of herpesvirus and influenza virus replication by blocking polymerase subunit interactions

artículo científico publicado en 2013

Inhibition of human cytomegalovirus DNA polymerase by C-terminal peptides from the UL54 subunit

artículo científico publicado en 2003

Measurement of ribavirin and evaluation of its stability in human plasma by high-performance liquid chromatography with UV detection

artículo científico publicado en 2007

Multiple phosphorylation sites at the C-terminus regulate nuclear import of HCMV DNA polymerase processivity factor ppUL44.

artículo científico publicado en 2011

Optimization of small-molecule inhibitors of influenza virus polymerase: from thiophene-3-carboxamide to polyamido scaffolds

artículo científico publicado en 2014

Protein-protein interactions as targets for antiviral chemotherapy

artículo científico publicado en 2002

Regulated transport into the nucleus of herpesviridae DNA replication core proteins

artículo científico publicado en 2013

Repurposing the clinically approved calcium antagonist manidipine dihydrochloride as a new early inhibitor of human cytomegalovirus targeting the Immediate-Early 2 (IE2) protein

artículo científico publicado en 2017

Role of homodimerization of human cytomegalovirus DNA polymerase accessory protein UL44 in origin-dependent DNA replication in cells

artículo científico publicado en 2008

Selective anti-cytomegalovirus compounds discovered by screening for inhibitors of subunit interactions of the viral polymerase

artículo científico publicado en 2006

Small molecule inhibitors of influenza A and B viruses that act by disrupting subunit interactions of the viral polymerase

artículo científico publicado en 2012

Structural investigation of cycloheptathiophene-3-carboxamide derivatives targeting influenza virus polymerase assembly

artículo científico publicado en 2013

Sulfated derivatives of Escherichia coli K5 capsular polysaccharide are potent inhibitors of human cytomegalovirus

artículo científico publicado en 2010

The 6-aminoquinolone WC5 inhibits human cytomegalovirus replication at an early stage by interfering with the transactivating activity of viral immediate-early 2 protein

artículo científico publicado en 2010

The Sp1 transcription factor does not directly interact with the HIV-1 Tat protein.

artículo científico publicado en 2003

The carboxy-terminal segment of the human cytomegalovirus DNA polymerase accessory subunit UL44 is crucial for viral replication

artículo científico publicado en 2010

The flexible loop of the human cytomegalovirus DNA polymerase processivity factor ppUL44 is required for efficient DNA binding and replication in cells

artículo científico publicado en 2009

The human cytomegalovirus DNA polymerase processivity factor UL44 is modified by SUMO in a DNA-dependent manner

artículo científico publicado en 2012

Unboosted fosamprenavir is associated with low drug exposure in HIV-infected patients with mild-moderate liver impairment resulting from HCV-related cirrhosis

artículo científico publicado en 2009

pH-Dependent conformational changes and topology of a herpesvirus translocating peptide in a membrane-mimetic environment

artículo científico publicado en 2004

Lista de obras de

4th European Seminars in Virology on Oncogenic and Oncolytic Viruses, in Bertinoro (Bologna), Italy.

A 6-aminoquinolone compound, WC5, with potent and selective anti-human cytomegalovirus activity

A Broad Anti-influenza Hybrid Small Molecule That Potently Disrupts the Interaction of Polymerase Acidic Protein-Basic Protein 1 (PA-PB1) Subunits

A point mutation in a herpesvirus polymerase determines neuropathogenicity

A quantitative LumiFluo assay to test inhibitory compounds blocking p53 degradation induced by human papillomavirus oncoprotein E6 in living cells

Analysis of the association of the human cytomegalovirus DNA polymerase subunit UL44 with the viral DNA replication factor UL84.

Antiviral properties of new arylsulfone derivatives with activity against human betaherpesviruses

Antiviral strategies against influenza virus: towards new therapeutic approaches

Approaches for the generation of new anti-cytomegalovirus agents: identification of protein-protein interaction inhibitors and compounds against the HCMV IE2 protein

Binding parameters and thermodynamics of the interaction of the human cytomegalovirus DNA polymerase accessory protein, UL44, with DNA: implications for the processivity mechanism

Cloning, expression, and functional characterization of the equine herpesvirus 1 DNA polymerase and its accessory subunit

Daclatasvir plasma level and resistance selection in HIV patients with hepatitis C virus cirrhosis treated with daclatasvir, sofosbuvir, and ribavirin

Design, synthesis, and evaluation of WC5 analogues as inhibitors of human cytomegalovirus Immediate-Early 2 protein, a promising target for anti-HCMV treatment

Development and validation of a simple and robust HPLC method with UV detection for quantification of the hepatitis C virus inhibitor daclatasvir in human plasma

Development of a simple HPLC-UV method for the determination of the hepatitis C virus inhibitor simeprevir in human plasma

Disruption of protein-protein interactions: towards new targets for chemotherapy

Drug Repurposing Approach Identifies Inhibitors of the Prototypic Viral Transcription Factor IE2 that Block Human Cytomegalovirus Replication

Drug Repurposing Campaigns for Human Cytomegalovirus Identify a Natural Compound Targeting the Immediate-Early 2 (IE2) Protein: A Comment on "The Natural Flavonoid Compound Deguelin Inhibits HCMV Lytic Replication within Fibroblasts"

Drug Repurposing for Viral Infectious Diseases: How Far Are We?

Early inhibitors of human cytomegalovirus: state-of-art and therapeutic perspectives

Effects of hepatitis C virus infection on the pharmacokinetics of ritonavir-boosted atazanavir in HIV-1-infected patients

Efficient and regioselective one-step synthesis of 7-aryl-5-methyl- and 5-aryl-7-methyl-2-amino-[1,2,4]triazolo[1,5-a]pyrimidine derivatives

HPV16 E6 and E7 upregulate the histone lysine demethylase KDM2B through the c-MYC/miR-146a-5p axys

Human cytomegalovirus DNA replication: antiviral targets and drugs

Human cytomegalovirus inhibitor AL18 also possesses activity against influenza A and B viruses

Inhibition of herpesvirus and influenza virus replication by blocking polymerase subunit interactions

Inhibition of human cytomegalovirus DNA polymerase by C-terminal peptides from the UL54 subunit

Measurement of ribavirin and evaluation of its stability in human plasma by high-performance liquid chromatography with UV detection

Multiple phosphorylation sites at the C-terminus regulate nuclear import of HCMV DNA polymerase processivity factor ppUL44.

Optimization of small-molecule inhibitors of influenza virus polymerase: from thiophene-3-carboxamide to polyamido scaffolds

Protein-protein interactions as targets for antiviral chemotherapy

Regulated transport into the nucleus of herpesviridae DNA replication core proteins

Repurposing the clinically approved calcium antagonist manidipine dihydrochloride as a new early inhibitor of human cytomegalovirus targeting the Immediate-Early 2 (IE2) protein

Role of homodimerization of human cytomegalovirus DNA polymerase accessory protein UL44 in origin-dependent DNA replication in cells

Selective anti-cytomegalovirus compounds discovered by screening for inhibitors of subunit interactions of the viral polymerase

Small molecule inhibitors of influenza A and B viruses that act by disrupting subunit interactions of the viral polymerase

Structural investigation of cycloheptathiophene-3-carboxamide derivatives targeting influenza virus polymerase assembly

Sulfated derivatives of Escherichia coli K5 capsular polysaccharide are potent inhibitors of human cytomegalovirus

The 6-aminoquinolone WC5 inhibits human cytomegalovirus replication at an early stage by interfering with the transactivating activity of viral immediate-early 2 protein

The Sp1 transcription factor does not directly interact with the HIV-1 Tat protein.

The carboxy-terminal segment of the human cytomegalovirus DNA polymerase accessory subunit UL44 is crucial for viral replication

The flexible loop of the human cytomegalovirus DNA polymerase processivity factor ppUL44 is required for efficient DNA binding and replication in cells

The human cytomegalovirus DNA polymerase processivity factor UL44 is modified by SUMO in a DNA-dependent manner

Unboosted fosamprenavir is associated with low drug exposure in HIV-infected patients with mild-moderate liver impairment resulting from HCV-related cirrhosis

pH-Dependent conformational changes and topology of a herpesvirus translocating peptide in a membrane-mimetic environment