Lista de obras -

A Regulated Double-Negative Feedback Decodes the Temporal Gradient of Input Stimulation in a Cell Signaling Network

artículo científico publicado en 2016

A checkpoints capturing timing-robust Boolean model of the budding yeast cell cycle regulatory network

artículo científico publicado en 2012

A design principle underlying the synchronization of oscillations in cellular systems

artículo científico publicado en 2010

A hybrid systems framework for cellular processes

artículo científico

A system-level investigation into the cellular toxic response mechanism mediated by AhR signal transduction pathway

artículo científico publicado en 2010

A unified framework for unraveling the functional interaction structure of a biomolecular network based on stimulus-response experimental data

artículo científico publicado en 2005

Advanced significance analysis of microarray data based on weighted resampling: a comparative study and application to gene deletions in Mycobacterium bovis

artículo científico publicado en 2004

An Efficient Steady-State Analysis Method for Large Boolean Networks with High Maximum Node Connectivity

artículo científico publicado en 2015

An efficient algorithm for identifying primary phenotype attractors of a large-scale Boolean network

artículo científico publicado en 2016

Analysis of feedback loops and robustness in network evolution based on Boolean models

artículo científico publicado en 2007

Attractor Landscape Analysis Reveals Feedback Loops in the p53 Network That Control the Cellular Response to DNA Damage ⬇️

artículo científico publicado el 20 de noviembre de 2012

Attractor landscape analysis of colorectal tumorigenesis and its reversion

artículo científico publicado en 2016

Coherent coupling of feedback loops: a design principle of cell signaling networks

artículo científico publicado en 2008

Combined Positive and Negative Feedback Allows Modulation of Neuronal Oscillation Frequency during Sensory Processing

artículo científico publicado en 2018

Coupled positive and negative feedback circuits form an essential building block of cellular signaling pathways

artículo científico publicado en 2007

Coupled positive feedbacks provoke slow induction plus fast switching in apoptosis

artículo científico publicado en 2007

Discovery of a kernel for controlling biomolecular regulatory networks

artículo científico publicado en 2013

Dynamic network rewiring determines temporal regulatory functions in Drosophila melanogaster development processes

artículo científico publicado en 2010

Dynamical analysis of the calcium signaling pathway in cardiac myocytes based on logarithmic sensitivity analysis

artículo científico publicado en 2008

Dynamical characteristics of bacteria clustering by self-generated attractants

artículo científico publicado en 2007

Dynamics of biological systems: role of systems biology in medical research

artículo científico publicado en 2006

ELECANS—an integrated model development environment for multiscale cancer systems biology ⬇️

artículo científico publicado el 6 de febrero de 2013

Evolutionary design principles and functional characteristics based on kingdom-specific network motifs ⬇️

artículo científico publicado el 11 de noviembre de 2010

Evolutionary design principles of modules that control cellular differentiation: consequences for hysteresis and multistationarity

artículo científico publicado en 2008

Functional roles of multiple feedback loops in extracellular signal-regulated kinase and Wnt signaling pathways that regulate epithelial-mesenchymal transition

artículo científico publicado en 2010

Hub genes with positive feedbacks function as master switches in developmental gene regulatory networks

artículo científico publicado en 2009

Identification of Gene Networks with Time Delayed Regulation Based on Temporal Expression Profiles

artículo científico publicado en 2015

Impaired coupling of local and global functional feedbacks underlies abnormal synchronization and negative symptoms of schizophrenia ⬇️

artículo científico publicado el 10 de abril de 2013

In silico identification of the key components and steps in IFN-gamma induced JAK-STAT signaling pathway

artículo científico publicado en 2005

Inferring biomolecular regulatory networks from phase portraits of time-series expression profiles

artículo científico publicado en 2006

Inferring gene regulatory networks from temporal expression profiles under time-delay and noise

artículo científico publicado en 2007

Integrative analysis of time course microarray data and DNA sequence data via log-linear models for identifying dynamic transcriptional regulatory networks

artículo científico publicado el 1 de enero de 2013

Interlinked mutual inhibitory positive feedbacks induce robust cellular memory effects

artículo científico publicado en 2007

Investigations into the analysis and modeling of the TNF alpha-mediated NF-kappa B-signaling pathway

artículo científico publicado en 2003

Investigations into the design principles in the chemotactic behavior of Escherichia coli

artículo científico publicado en 2007

Investigations into the relationship between feedback loops and functional importance of a signal transduction network based on Boolean network modeling

artículo científico publicado en 2007

Least-squares methods for identifying biochemical regulatory networks from noisy measurements

artículo científico publicado en 2007

Level sets and minimum volume sets of probability density functions

Linear time-varying models can reveal non-linear interactions of biomolecular regulatory networks using multiple time-series data

artículo científico publicado en 2008

MLK3 is part of a feedback mechanism that regulates different cellular responses to reactive oxygen species

artículo científico publicado en 2014

Microarray data clustering based on temporal variation: FCV with TSD preclustering.

artículo científico publicado en 2003

Modeling and simulation of intracellular dynamics: choosing an appropriate framework

artículo científico publicado en 2004

Modelling gene expression time-series with radial basis function neural networks

article

Modelling the dynamics of signalling pathways

artículo científico publicado en 2008

Multiple roles of the NF-kappaB signaling pathway regulated by coupled negative feedback circuits

artículo científico publicado en 2009

Network-based identification of feedback modules that control RhoA activity and cell migration

artículo científico publicado en 2015

Optimal sampling time selection for parameter estimation in dynamic pathway modeling

artículo científico publicado en 2004

Positive- and negative-feedback regulations coordinate the dynamic behavior of the Ras-Raf-MEK-ERK signal transduction pathway

artículo científico publicado en 2009

Quantitative analysis of robustness and fragility in biological networks based on feedback dynamics

artículo científico publicado en 2008

Quantitative evaluation and reversion analysis of the attractor landscapes of an intracellular regulatory network for colorectal cancer

artículo científico publicado en 2017

Recurrent connections form a phase-locking neuronal tuner for frequency-dependent selective communication ⬇️

artículo científico publicado el 1 de enero de 2013

Reduction of Complex Signaling Networks to a Representative Kernel ⬇️

artículo científico publicado el 31 de mayo de 2011

Robustness and evolvability of the human signaling network

artículo científico publicado en 2014

Silence on the relevant literature and errors in implementation

artículo científico publicado en 2015

Spatiotemporal network motif reveals the biological traits of developmental gene regulatory networks in Drosophila melanogaster ⬇️

artículo científico publicado el 1 de mayo de 2012

System-level investigation into the regulatory mechanism of the calcineurin/NFAT signaling pathway

artículo científico publicado en 2008

The APC network regulates the removal of mutated cells from colonic crypts

artículo científico publicado en 2014

The biphasic behavior of incoherent feed-forward loops in biomolecular regulatory networks

artículo científico publicado en 2008

The co-regulation mechanism of transcription factors in the human gene regulatory network ⬇️

artículo científico publicado el 13 de julio de 2012

The core regulation module of stress-responsive regulatory networks in yeast ⬇️

artículo científico publicado el 10 de julio de 2012

The crossregulation between ERK and PI3K signaling pathways determines the tumoricidal efficacy of MEK inhibitor

artículo científico publicado en 2012

The dynamic systems approach to control and regulation of intracellular networks

artículo científico publicado en 2005

The hidden switches underlying RORα-mediated circuits that critically regulate uncontrolled cell proliferation

artículo científico publicado en 2014

The multi-step phosphorelay mechanism of unorthodox two-component systems in E. coli realizes ultrasensitivity to stimuli while maintaining robustness to noises

artículo científico publicado en 2006

The phenotype control kernel of a biomolecular regulatory network

artículo científico publicado en 2018

The regulatory circuits for hysteretic switching in cellular signal transduction pathways

artículo científico publicado en 2012

The reverse control of irreversible biological processes

artículo científico publicado en 2016

The role of dynamic stimulation pattern in the analysis of bistable intracellular networks

artículo científico publicado en 2008

The statistical distribution of the intensity of pixels within spots of DNA microarrays: what is the appropriate single-value representative?

artículo científico publicado en 2003

Unraveling the functional interaction structure of a biomolecular network through alternate perturbation of initial conditions

artículo científico publicado en 2007

Unravelling the functional interaction structure of a cellular network from temporal slope information of experimental data

artículo científico publicado en 2005

Why have serine/threonine/tyrosine kinases been evolutionarily selected in eukaryotic signaling cascades?

artículo científico publicado en 2008

Wnt pathway mutations selected by optimal beta-catenin signaling for tumorigenesis

artículo científico publicado en 2006

Lista de obras de

A Regulated Double-Negative Feedback Decodes the Temporal Gradient of Input Stimulation in a Cell Signaling Network

A checkpoints capturing timing-robust Boolean model of the budding yeast cell cycle regulatory network

A design principle underlying the synchronization of oscillations in cellular systems

A hybrid systems framework for cellular processes

A system-level investigation into the cellular toxic response mechanism mediated by AhR signal transduction pathway

A unified framework for unraveling the functional interaction structure of a biomolecular network based on stimulus-response experimental data

Advanced significance analysis of microarray data based on weighted resampling: a comparative study and application to gene deletions in Mycobacterium bovis

An Efficient Steady-State Analysis Method for Large Boolean Networks with High Maximum Node Connectivity

An efficient algorithm for identifying primary phenotype attractors of a large-scale Boolean network

Analysis of feedback loops and robustness in network evolution based on Boolean models

Attractor Landscape Analysis Reveals Feedback Loops in the p53 Network That Control the Cellular Response to DNA Damage ⬇️

Attractor landscape analysis of colorectal tumorigenesis and its reversion

Coherent coupling of feedback loops: a design principle of cell signaling networks

Combined Positive and Negative Feedback Allows Modulation of Neuronal Oscillation Frequency during Sensory Processing

Coupled positive and negative feedback circuits form an essential building block of cellular signaling pathways

Coupled positive feedbacks provoke slow induction plus fast switching in apoptosis

Discovery of a kernel for controlling biomolecular regulatory networks

Dynamic network rewiring determines temporal regulatory functions in Drosophila melanogaster development processes

Dynamical analysis of the calcium signaling pathway in cardiac myocytes based on logarithmic sensitivity analysis

Dynamical characteristics of bacteria clustering by self-generated attractants

Dynamics of biological systems: role of systems biology in medical research

ELECANS—an integrated model development environment for multiscale cancer systems biology ⬇️

Evolutionary design principles and functional characteristics based on kingdom-specific network motifs ⬇️

Evolutionary design principles of modules that control cellular differentiation: consequences for hysteresis and multistationarity

Functional roles of multiple feedback loops in extracellular signal-regulated kinase and Wnt signaling pathways that regulate epithelial-mesenchymal transition

Hub genes with positive feedbacks function as master switches in developmental gene regulatory networks

Identification of Gene Networks with Time Delayed Regulation Based on Temporal Expression Profiles

Impaired coupling of local and global functional feedbacks underlies abnormal synchronization and negative symptoms of schizophrenia ⬇️

In silico identification of the key components and steps in IFN-gamma induced JAK-STAT signaling pathway

Inferring biomolecular regulatory networks from phase portraits of time-series expression profiles

Inferring gene regulatory networks from temporal expression profiles under time-delay and noise

Integrative analysis of time course microarray data and DNA sequence data via log-linear models for identifying dynamic transcriptional regulatory networks

Interlinked mutual inhibitory positive feedbacks induce robust cellular memory effects

Investigations into the analysis and modeling of the TNF alpha-mediated NF-kappa B-signaling pathway

Investigations into the design principles in the chemotactic behavior of Escherichia coli

Investigations into the relationship between feedback loops and functional importance of a signal transduction network based on Boolean network modeling

Least-squares methods for identifying biochemical regulatory networks from noisy measurements

Level sets and minimum volume sets of probability density functions

Linear time-varying models can reveal non-linear interactions of biomolecular regulatory networks using multiple time-series data

MLK3 is part of a feedback mechanism that regulates different cellular responses to reactive oxygen species

Microarray data clustering based on temporal variation: FCV with TSD preclustering.

Modeling and simulation of intracellular dynamics: choosing an appropriate framework

Modelling gene expression time-series with radial basis function neural networks

Modelling the dynamics of signalling pathways

Multiple roles of the NF-kappaB signaling pathway regulated by coupled negative feedback circuits

Network-based identification of feedback modules that control RhoA activity and cell migration

Optimal sampling time selection for parameter estimation in dynamic pathway modeling

Positive- and negative-feedback regulations coordinate the dynamic behavior of the Ras-Raf-MEK-ERK signal transduction pathway

Quantitative analysis of robustness and fragility in biological networks based on feedback dynamics

Quantitative evaluation and reversion analysis of the attractor landscapes of an intracellular regulatory network for colorectal cancer

Recurrent connections form a phase-locking neuronal tuner for frequency-dependent selective communication ⬇️

Reduction of Complex Signaling Networks to a Representative Kernel ⬇️

Robustness and evolvability of the human signaling network

Silence on the relevant literature and errors in implementation

Spatiotemporal network motif reveals the biological traits of developmental gene regulatory networks in Drosophila melanogaster ⬇️

System-level investigation into the regulatory mechanism of the calcineurin/NFAT signaling pathway

The APC network regulates the removal of mutated cells from colonic crypts

The biphasic behavior of incoherent feed-forward loops in biomolecular regulatory networks

The co-regulation mechanism of transcription factors in the human gene regulatory network ⬇️

The core regulation module of stress-responsive regulatory networks in yeast ⬇️

The crossregulation between ERK and PI3K signaling pathways determines the tumoricidal efficacy of MEK inhibitor

The dynamic systems approach to control and regulation of intracellular networks

The hidden switches underlying RORα-mediated circuits that critically regulate uncontrolled cell proliferation

The multi-step phosphorelay mechanism of unorthodox two-component systems in E. coli realizes ultrasensitivity to stimuli while maintaining robustness to noises

The phenotype control kernel of a biomolecular regulatory network

The regulatory circuits for hysteretic switching in cellular signal transduction pathways

The reverse control of irreversible biological processes

The role of dynamic stimulation pattern in the analysis of bistable intracellular networks

The statistical distribution of the intensity of pixels within spots of DNA microarrays: what is the appropriate single-value representative?

Unraveling the functional interaction structure of a biomolecular network through alternate perturbation of initial conditions

Unravelling the functional interaction structure of a cellular network from temporal slope information of experimental data

Why have serine/threonine/tyrosine kinases been evolutionarily selected in eukaryotic signaling cascades?

Wnt pathway mutations selected by optimal beta-catenin signaling for tumorigenesis