Lista de obras -

"It is not guaranteed that you will benefit": True but misleading?

artículo científico publicado en 2015

A longitudinal program for biomarker development in Parkinson's disease: a feasibility study

artículo científico publicado en 2009

A phase 3 trial of semagacestat for treatment of Alzheimer's disease

artículo científico publicado en 2013

A practical approach to remote longitudinal follow-up of Parkinson's disease: the FOUND study

artículo científico publicado en 2014

A randomized controlled trial of etilevodopa in patients with Parkinson disease who have motor fluctuations

artículo científico publicado en 2006

A randomized trial of a low-dose Rasagiline and Pramipexole combination (P2B001) in early Parkinson's disease.

artículo científico publicado en 2017

A randomized, double-blind, placebo-controlled trial of coenzyme Q10 in Huntington disease

artículo científico

A randomized, placebo-controlled trial of latrepirdine in Huntington disease

artículo científico publicado en 2010

A randomized, placebo-controlled trial of oxycodone and of gabapentin for acute pain in herpes zoster

artículo científico

A responsive outcome for Parkinson's disease neuroprotection futility studies

artículo científico publicado en 2005

A review of disease progression models of Parkinson's disease and applications in clinical trials

artículo científico publicado en 2016

ADAGIO misses a beat?

artículo científico publicado en 2009

Advances in clinical trials for movement disorders

artículo científico

Advocacy Recruiting for Huntington’s Disease Clinical Trials ⬇️

artículo científico publicado el 12 de abril de 2011

An approach to evaluating the therapeutic misconception

artículo científico publicado en 2009

Appointing a proxy for research consent after one develops dementia: the need for further study

artículo científico publicado en 2006

Are patients with amyotrophic lateral sclerosis at risk of a therapeutic misconception?

artículo científico publicado en 2016

Are therapeutic motivation and having one's own doctor as researcher sources of therapeutic misconception?

artículo científico publicado en 2014

Association of cerebrospinal fluid β-amyloid 1-42, T-tau, P-tau181, and α-synuclein levels with clinical features of drug-naive patients with early Parkinson disease

artículo científico publicado en 2013

Attenuated central nervous system infection in advanced HIV/AIDS with combination antiretroviral therapy

artículo científico publicado en 2004

Baseline prevalence and longitudinal evolution of non-motor symptoms in early Parkinson's disease: the PPMI cohort

artículo científico publicado en 2017

Beyond disgust: impaired recognition of negative emotions prior to diagnosis in Huntington's disease

artículo científico publicado en 2007

Biomarker-driven phenotyping in Parkinson's disease: A translational missing link in disease-modifying clinical trials

artículo científico publicado en 2017

Building Capacity Across the Spectrum of Research Translation: Centers of Excellence within the Rochester Clinical and Translational Science Institute ⬇️

artículo científico publicado el 1 de diciembre de 2010

CSF biomarkers associated with disease heterogeneity in early Parkinson's disease: the Parkinson's Progression Markers Initiative study

artículo científico publicado en 2016

CTSA Consortium Consensus Scientific Review Committee (SRC) Working Group Report on the SRC Processes

artículo científico publicado en 2015

Cancer incidence in a trial of an antiapoptotic agent for Parkinson's disease

artículo científico publicado en 2010

Clinical and Dopamine Transporter Imaging Characteristics of Leucine- Rich Repeat Kinase 2 (LRRK2) and Glucosylceramidase Beta (GBA) Parkinson's Disease Participants in the Parkinson's Progression Markers Initiative: A Cross-Sectional Study

scientific article published on 19 February 2020

Clinical-Genetic Associations in the Prospective Huntington at Risk Observational Study (PHAROS): Implications for Clinical Trials

artículo científico publicado en 2015

Comparison of enrollees and decliners of Parkinson disease sham surgery trials ⬇️

artículo científico publicado el 7 de febrero de 2012

Continuous intrajejunal infusion of levodopa-carbidopa intestinal gel for patients with advanced Parkinson's disease: a randomised, controlled, double-blind, double-dummy study

artículo científico publicado en 2013

Core assessment program for intracerebral transplantation in Huntington's disease (CAPIT-HD)

Could the High Prevalence of Therapeutic Misconception Partly Be a Measurement Problem?

artículo científico publicado en 2015

Defining disease‐modifying therapies for PD—A road map for moving forward ⬇️

artículo científico publicado el 15 de septiembre de 2010

Design considerations for a multicenter randomized controlled trial of early surgery for mesial temporal lobe epilepsy

artículo científico publicado en 2010

Designing clinical trials for dystonia

scientific article published on January 2014

Designing neuroprotection trials in Parkinson's disease

artículo científico publicado en 2003

Disease progression and pharmacodynamics in Parkinson disease - evidence for functional protection with levodopa and other treatments

artículo científico publicado en 2006

Early surgical therapy for drug-resistant temporal lobe epilepsy: a randomized trial.

artículo científico publicado en 2012

Education and training of clinical and translational study investigators and research coordinators: A competency-based approach

Effect of L-methionine on hot flashes in postmenopausal women: a randomized controlled trial

artículo científico publicado en 2009

Effect of creatine monohydrate on clinical progression in patients with Parkinson disease: a randomized clinical trial

artículo científico publicado en 2015

Effects of L-isoleucine and L-valine on hot flushes and serum homocysteine: a randomized controlled trial

artículo científico publicado en 2008

Effects of coenzyme Q10 in early Parkinson disease: evidence of slowing of the functional decline

artículo científico publicado en 2002

Ethics of sham surgery: perspective of patients

artículo científico publicado en 2008

Evidence-based research ethics and determinations of "engagement in research"

artículo científico publicado en 2014

Factors predictive of the development of Levodopa-induced dyskinesia and wearing-off in Parkinson's disease

artículo científico publicado en 2013

Gabapentin's effects on hot flashes in postmenopausal women: a randomized controlled trial

artículo científico publicado en 2003

Gene delivery of AAV2-neurturin for Parkinson's disease: a double-blind, randomised, controlled trial

artículo científico publicado en 2010

Huntington's disease: Current and future therapeutic prospects

artículo científico publicado en 2018

Impact of sustained deprenyl (selegiline) in levodopa-treated Parkinson's disease: a randomized placebo-controlled extension of the deprenyl and tocopherol antioxidative therapy of parkinsonism trial

artículo científico publicado en 2002

Increased levels of total tau protein in the cerebrospinal fluid in Huntington's disease

artículo científico publicado en 2011

Initiating levodopa/carbidopa therapy with and without entacapone in early Parkinson disease: the STRIDE-PD study

artículo científico publicado en 2010

Interrater agreement in the assessment of motor manifestations of Huntington's disease

artículo científico publicado en 2005

Levels of the light subunit of neurofilament triplet protein in cerebrospinal fluid in Huntington's disease

artículo científico publicado en 2008

Levodopa and the progression of Parkinson's disease

artículo científico publicado en 2004

Long term understanding of study information in research participants with Parkinson's disease

artículo científico publicado en 2009

Longer Duration of MAO-B Inhibitor Exposure is Associated with Less Clinical Decline in Parkinson's Disease: An Analysis of NET-PD LS1.

artículo científico publicado en 2016

Longitudinal change of clinical and biological measures in early Parkinson's disease: Parkinson's progression markers initiative cohort

artículo científico publicado en 2018

Malignant melanoma in early-treated Parkinson's disease: the NET-PD trial

artículo científico publicado en 2013

Milestones in movement disorders clinical trials: Advances and landmark studies ⬇️

artículo científico publicado el 1 de mayo de 2011

Moving Parkinson care to the home

artículo científico publicado en 2016

New drugs for Parkinson's disease: The regulatory and clinical development pathways in the United States

artículo científico publicado en 2017

Non-linearity of Parkinson's disease progression: implications for sample size calculations in clinical trials

artículo científico publicado en 2005

Novel methods and technologies for 21st-century clinical trials: a review

artículo científico publicado en 2015

Oral repeated-dose toxicity studies of coenzyme Q10 in beagle dogs

artículo científico publicado en 2012

Parkinson's disease: Evidence for environmental risk factors ⬇️

artículo científico publicado el 24 de octubre de 2012

Pharmacologic approaches to the treatment of Huntington's disease

artículo científico publicado el 13 de octubre de 2011

Phase 3 trials of solanezumab for mild-to-moderate Alzheimer's disease

artículo científico publicado en 2014

Pivotal studies of orphan drugs approved for neurological diseases

artículo científico publicado en 2009

Pramipexole vs levodopa as initial treatment for Parkinson disease: a 4-year randomized controlled trial

artículo científico publicado en 2004

Preparing for preventive clinical trials: the Predict-HD study

artículo científico publicado en 2006

Rasagiline improves quality of life in patients with early Parkinson's disease

artículo científico publicado en 2006

Research participants' "irrational" expectations: common or commonly mismeasured?

artículo científico publicado el 1 de enero de 2013

Results of the citalopram to enhance cognition in Huntington disease trial

artículo científico publicado en 2013

Safety and Exploratory Efficacy at 36 Months in Open-HART, an Open-Label Extension Study of Pridopidine in Huntington's Disease

artículo científico publicado en 2017

Safety and tolerability of high-dosage coenzyme Q10 in Huntington's disease and healthy subjects

artículo científico publicado en 2010

Science and ethics of sham surgery: a survey of Parkinson disease clinical researchers

artículo científico publicado en 2005

Serum urate as a predictor of clinical and radiographic progression in Parkinson disease

artículo científico publicado en 2008

TCH346 as a neuroprotective drug in Parkinson's disease: a double-blind, randomised, controlled trial

artículo científico publicado en 2006

TRACK-HD: both promise and disappointment ⬇️

artículo científico publicado el 2 de diciembre de 2011

Test-retest reliability of the unified Parkinson's disease rating scale in patients with early Parkinson's disease: results from a multicenter clinical trial

artículo científico publicado en 2002

The Parkinson's progression markers initiative (PPMI) - establishing a PD biomarker cohort

scientific article published on 31 October 2018

The idiopathic intracranial hypertension treatment trial: design considerations and methods

artículo científico publicado en 2014

The relationship between CAG repeat length and clinical progression in Huntington's disease

artículo científico publicado en 2008

The relationship between uric acid levels and Huntington's disease progression

artículo científico publicado en 2010

Therapeutic development paths for cognitive impairment in Parkinson's disease: report of a regulatory roundtable

artículo científico publicado en 2014

Therapeutic strategies to prevent motor complications in Parkinson's disease

artículo científico publicado en 2008

Toward more efficient clinical trials for amyotrophic lateral sclerosis

artículo científico publicado en 2010

Translational experimental therapeutics: The translation of laboratory-based discovery into disease-related therapy

artículo científico publicado en 2007

Trust in early phase research: therapeutic optimism and protective pessimism

artículo científico publicado en 2008

Understanding the 'therapeutic misconception' from the research participant's perspective

artículo científico publicado en 2016

Urate as a predictor of the rate of clinical decline in Parkinson disease

artículo científico publicado en 2009

Using global statistical tests in long-term Parkinson's disease clinical trials

artículo científico publicado en 2009

Verbal episodic memory declines prior to diagnosis in Huntington's disease

artículo científico publicado en 2007

Welding and Parkinson disease: is there a bond?

artículo científico publicado en 2005

What is the risk of sham surgery in Parkinson disease clinical trials? A review of published reports

artículo científico publicado en 2005

Why hasn't neuroprotection worked in Parkinson's disease?

artículo científico publicado en 2007

Why have we failed to achieve neuroprotection in Parkinson's disease?

scientific article published on December 2008

Lista de obras de

"It is not guaranteed that you will benefit": True but misleading?

A longitudinal program for biomarker development in Parkinson's disease: a feasibility study

A phase 3 trial of semagacestat for treatment of Alzheimer's disease

A practical approach to remote longitudinal follow-up of Parkinson's disease: the FOUND study

A randomized controlled trial of etilevodopa in patients with Parkinson disease who have motor fluctuations

A randomized trial of a low-dose Rasagiline and Pramipexole combination (P2B001) in early Parkinson's disease.

A randomized, double-blind, placebo-controlled trial of coenzyme Q10 in Huntington disease

A randomized, placebo-controlled trial of latrepirdine in Huntington disease

A randomized, placebo-controlled trial of oxycodone and of gabapentin for acute pain in herpes zoster

A responsive outcome for Parkinson's disease neuroprotection futility studies

A review of disease progression models of Parkinson's disease and applications in clinical trials

ADAGIO misses a beat?

Advances in clinical trials for movement disorders

Advocacy Recruiting for Huntington’s Disease Clinical Trials ⬇️

An approach to evaluating the therapeutic misconception

Appointing a proxy for research consent after one develops dementia: the need for further study

Are patients with amyotrophic lateral sclerosis at risk of a therapeutic misconception?

Are therapeutic motivation and having one's own doctor as researcher sources of therapeutic misconception?

Association of cerebrospinal fluid β-amyloid 1-42, T-tau, P-tau181, and α-synuclein levels with clinical features of drug-naive patients with early Parkinson disease

Attenuated central nervous system infection in advanced HIV/AIDS with combination antiretroviral therapy

Baseline prevalence and longitudinal evolution of non-motor symptoms in early Parkinson's disease: the PPMI cohort

Beyond disgust: impaired recognition of negative emotions prior to diagnosis in Huntington's disease

Biomarker-driven phenotyping in Parkinson's disease: A translational missing link in disease-modifying clinical trials

Building Capacity Across the Spectrum of Research Translation: Centers of Excellence within the Rochester Clinical and Translational Science Institute ⬇️

CSF biomarkers associated with disease heterogeneity in early Parkinson's disease: the Parkinson's Progression Markers Initiative study

CTSA Consortium Consensus Scientific Review Committee (SRC) Working Group Report on the SRC Processes

Cancer incidence in a trial of an antiapoptotic agent for Parkinson's disease

Clinical and Dopamine Transporter Imaging Characteristics of Leucine- Rich Repeat Kinase 2 (LRRK2) and Glucosylceramidase Beta (GBA) Parkinson's Disease Participants in the Parkinson's Progression Markers Initiative: A Cross-Sectional Study

Clinical-Genetic Associations in the Prospective Huntington at Risk Observational Study (PHAROS): Implications for Clinical Trials

Comparison of enrollees and decliners of Parkinson disease sham surgery trials ⬇️

Continuous intrajejunal infusion of levodopa-carbidopa intestinal gel for patients with advanced Parkinson's disease: a randomised, controlled, double-blind, double-dummy study

Core assessment program for intracerebral transplantation in Huntington's disease (CAPIT-HD)

Could the High Prevalence of Therapeutic Misconception Partly Be a Measurement Problem?

Defining disease‐modifying therapies for PD—A road map for moving forward ⬇️

Design considerations for a multicenter randomized controlled trial of early surgery for mesial temporal lobe epilepsy

Designing clinical trials for dystonia

Designing neuroprotection trials in Parkinson's disease

Disease progression and pharmacodynamics in Parkinson disease - evidence for functional protection with levodopa and other treatments

Early surgical therapy for drug-resistant temporal lobe epilepsy: a randomized trial.

Education and training of clinical and translational study investigators and research coordinators: A competency-based approach

Effect of L-methionine on hot flashes in postmenopausal women: a randomized controlled trial

Effect of creatine monohydrate on clinical progression in patients with Parkinson disease: a randomized clinical trial

Effects of L-isoleucine and L-valine on hot flushes and serum homocysteine: a randomized controlled trial

Effects of coenzyme Q10 in early Parkinson disease: evidence of slowing of the functional decline

Ethics of sham surgery: perspective of patients

Evidence-based research ethics and determinations of "engagement in research"

Factors predictive of the development of Levodopa-induced dyskinesia and wearing-off in Parkinson's disease

Gabapentin's effects on hot flashes in postmenopausal women: a randomized controlled trial

Gene delivery of AAV2-neurturin for Parkinson's disease: a double-blind, randomised, controlled trial

Huntington's disease: Current and future therapeutic prospects

Impact of sustained deprenyl (selegiline) in levodopa-treated Parkinson's disease: a randomized placebo-controlled extension of the deprenyl and tocopherol antioxidative therapy of parkinsonism trial

Increased levels of total tau protein in the cerebrospinal fluid in Huntington's disease

Initiating levodopa/carbidopa therapy with and without entacapone in early Parkinson disease: the STRIDE-PD study

Interrater agreement in the assessment of motor manifestations of Huntington's disease

Levels of the light subunit of neurofilament triplet protein in cerebrospinal fluid in Huntington's disease

Levodopa and the progression of Parkinson's disease

Long term understanding of study information in research participants with Parkinson's disease

Longer Duration of MAO-B Inhibitor Exposure is Associated with Less Clinical Decline in Parkinson's Disease: An Analysis of NET-PD LS1.

Longitudinal change of clinical and biological measures in early Parkinson's disease: Parkinson's progression markers initiative cohort

Malignant melanoma in early-treated Parkinson's disease: the NET-PD trial

Milestones in movement disorders clinical trials: Advances and landmark studies ⬇️

Moving Parkinson care to the home

New drugs for Parkinson's disease: The regulatory and clinical development pathways in the United States

Non-linearity of Parkinson's disease progression: implications for sample size calculations in clinical trials

Novel methods and technologies for 21st-century clinical trials: a review

Oral repeated-dose toxicity studies of coenzyme Q10 in beagle dogs

Parkinson's disease: Evidence for environmental risk factors ⬇️

Pharmacologic approaches to the treatment of Huntington's disease

Phase 3 trials of solanezumab for mild-to-moderate Alzheimer's disease

Pivotal studies of orphan drugs approved for neurological diseases

Pramipexole vs levodopa as initial treatment for Parkinson disease: a 4-year randomized controlled trial

Preparing for preventive clinical trials: the Predict-HD study

Rasagiline improves quality of life in patients with early Parkinson's disease

Research participants' "irrational" expectations: common or commonly mismeasured?

Results of the citalopram to enhance cognition in Huntington disease trial

Safety and Exploratory Efficacy at 36 Months in Open-HART, an Open-Label Extension Study of Pridopidine in Huntington's Disease

Safety and tolerability of high-dosage coenzyme Q10 in Huntington's disease and healthy subjects

Science and ethics of sham surgery: a survey of Parkinson disease clinical researchers

Serum urate as a predictor of clinical and radiographic progression in Parkinson disease