Filtros de búsqueda

Lista de obras de

A conserved retromer sorting motif is essential for mitochondrial DLP1 recycling by VPS35 in Parkinson's disease model

artículo científico publicado en 2016

A low-molecular-weight ferroxidase is increased in the CSF of sCJD cases: CSF ferroxidase and transferrin as diagnostic biomarkers for sCJD.

artículo científico publicado en 2013

A novel origin for granulovacuolar degeneration in aging and Alzheimer's disease: parallels to stress granules

artículo científico publicado en 2011

A second look into the oxidant mechanisms in Alzheimer's disease

artículo científico publicado en 2005

A synergistic dysfunction of mitochondrial fission/fusion dynamics and mitophagy in Alzheimer's disease

artículo científico publicado en 2010

Aberrant expression of metabotropic glutamate receptor 2 in the vulnerable neurons of Alzheimer's disease

artículo científico publicado en 2004

Aberrant localization of importin alpha1 in hippocampal neurons in Alzheimer disease

artículo científico publicado en 2006

Abnormal mitochondrial dynamics and neurodegenerative diseases

artículo científico publicado en 2009

Abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease

artículo científico publicado en 2013

Abnormal mitochondrial dynamics--a novel therapeutic target for Alzheimer's disease?

artículo científico publicado en 2010

Absence of cellular stress in brain after hypoxia induced by arousal from hibernation in Arctic ground squirrels

artículo científico publicado en 2005

Accumulation of intraneuronal amyloid-β is common in normal brain.

artículo científico publicado en 2014

Activation of Akt by lithium: pro-survival pathways in aging

artículo científico publicado en 2009

Activation of P38 kinase links π phosphorylation, oxidative stress and cell cycle-related events in Alzheimer disease

Activation of the extracellular signal-regulated kinase pathway contributes to the behavioral deficit of fragile x-syndrome

artículo científico publicado en 2012

All-trans retinoic acid as a novel therapeutic strategy for Alzheimer's disease

artículo científico publicado en 2009

Altered redox balance in disease: Can we change the new equilibria?

Alzheimer Disease: Oxidative Stress and Compensatory Responses

artículo científico

Alzheimer disease and the role of free radicals in the pathogenesis of the disease

scientific article published on February 2008

Alzheimer disease pathology as a host response

scientific article published on June 2008

Alzheimer disease, the two-hit hypothesis: an update

artículo científico publicado en 2006

Alzheimer disease: evidence for a central pathogenic role of iron-mediated reactive oxygen species

artículo científico publicado en 2004

Alzheimer's Disease: Advances for a New Century

scholarly article by George Perry et al published 27 December 2012 in Journal of Alzheimer's Disease

Alzheimer's disease and the cell cycle

artículo científico publicado en 2004

Alzheimer's disease and vascular deficiency: lessons from imaging studies and down syndrome

artículo científico publicado en 2012

Alzheimer's disease: an intracellular movement disorder?

artículo científico publicado en 2005

Alzheimer's disease: cerebrovascular dysfunction, oxidative stress, and advanced clinical therapies

artículo científico publicado en 2008

Alzheimer's disease: diverse aspects of mitochondrial malfunctioning

artículo científico publicado en 2010

Alzheimer's disease: the two-hit hypothesis

artículo científico publicado en 2004

Alzheimer-specific epitopes of tau represent lipid peroxidation-induced conformations

artículo científico publicado en 2005

Alzheimers Disease and Oxidative Stress: The Old Problem Remains Unsolved

scholarly article published 1 March 2005

Alzheimer’s disease therapy: a moving target

Amyloid Beta and tau proteins as therapeutic targets for Alzheimer's disease treatment: rethinking the current strategy

artículo científico publicado en 2012

Amyloid beta: the alternate hypothesis

artículo científico publicado en 2006

Amyloid-beta in Alzheimer's disease: the horse or the cart? Pathogenic or protective?

artículo científico publicado en 2005

Amyloid-beta overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins

scholarly article

Amyloid-beta vaccination: testing the amyloid hypothesis?: heads we win, tails you lose!

artículo científico publicado en 2006

Amyloid-beta, tau alterations and mitochondrial dysfunction in Alzheimer disease: the chickens or the eggs?

artículo científico publicado en 2002

Amyloid-beta-derived diffusible ligands cause impaired axonal transport of mitochondria in neurons

artículo científico publicado en 2010

Amyloid-β metabolite sensing: biochemical linking of glycation modification and misfolding

artículo científico publicado en 2012

Amyloid-β42 Interacts Mainly with Insoluble Prion Protein in the Alzheimer Brain ⬇️

artículo científico publicado el 10 de marzo de 2011

Amyloids, Aggregates and Neuronal Inclusions: Good or Bad News for Neurons?

article

Amyotrophic lateral sclerosis: a novel hypothesis involving a gained 'loss of function' in the JNK/SAPK pathway

artículo científico publicado en 2003

Antigen-antibody dissociation in Alzheimer disease: a novel approach to diagnosis

artículo científico publicado en 2008

Antimicrobial peptide β-defensin-1 expression is upregulated in Alzheimer's brain

artículo científico publicado en 2013

Antioxidant approaches for the treatment of Alzheimer's disease

artículo científico publicado en 2010

Antioxidant therapy in Alzheimer's disease: theory and practice

artículo científico publicado en 2008

Apolipoprotein E4 prevents growth of malaria at the intraerythrocyte stage: implications for differences in racial susceptibility to Alzheimer's disease

artículo científico publicado en 2013

Apoptosis in Alzheimer disease: a mathematical improbability

artículo científico publicado en 2006

Apoptotic and Oxidative Indicators in Alzheimer's Disease

scholarly article

Apoptotic promoters and inhibitors in Alzheimer's disease: Who wins out?

artículo científico publicado en 2003

Ascorbate distribution during hibernation is independent of ascorbate redox state

artículo científico publicado en 2004

Autophagocytosis of mitochondria is prominent in Alzheimer disease

artículo científico publicado en 2007

Autophagy in Alzheimer's disease

artículo científico publicado en 2010

BRCA1 may modulate neuronal cell cycle re-entry in Alzheimer disease

artículo científico publicado en 2007

Beyond estrogen: targeting gonadotropin hormones in the treatment of Alzheimer's disease

artículo científico publicado en 2004

Biomarkers in Alzheimer's disease: past, present and future

artículo científico publicado en 2010

Birth of JAD: 20 Years Later.

artículo científico publicado en 2018

CD3 in Lewy pathology: does the abnormal recall of neurodevelopmental processes underlie Parkinson's disease

artículo científico publicado en 2010

Causes versus effects: the increasing complexities of Alzheimer's disease pathogenesis

artículo científico publicado en 2010

Cell cycle deregulation in the neurons of Alzheimer's disease

artículo científico publicado en 2011

Cell cycle re-entry and mitochondrial defects in myc-mediated hypertrophic cardiomyopathy and heart failure

artículo científico publicado en 2009

Cell cycle re-entry mediated neurodegeneration and its treatment role in the pathogenesis of Alzheimer's disease

scientific article published on 09 December 2008

Cellular prion protein is essential for oligomeric amyloid-β-induced neuronal cell death

artículo científico publicado en 2011

Challenging the amyloid cascade hypothesis: senile plaques and amyloid-beta as protective adaptations to Alzheimer disease

artículo científico publicado en 2004

Chapter 19. Targeting Oxidative Mechanisms in Alzheimer Disease

Chronic Leptin Supplementation Ameliorates Pathology and Improves Cognitive Performance in a Transgenic Mouse Model of Alzheimer's Disease

artículo científico publicado en 2009

Chronic oxidative stress causes increased tau phosphorylation in M17 neuroblastoma cells

artículo científico publicado en 2009

Chronological primacy of oxidative stress in Alzheimer disease.

artículo científico publicado en 2005

Clinical and imaging characteristics of late onset mitochondrial membrane protein-associated neurodegeneration (MPAN)

artículo científico publicado en 2016

Comparative biology and pathology of oxidative stress in Alzheimer and other neurodegenerative diseases: beyond damage and response

artículo científico publicado en 2002

Compensatory responses induced by oxidative stress in Alzheimer disease

artículo científico publicado en 2006

Consequences of RNA oxidation on protein synthesis rate and fidelity: implications for the pathophysiology of neuropsychiatric disorders

artículo científico publicado en 2017

Contribution of redox-active iron and copper to oxidative damage in Alzheimer disease

artículo científico publicado en 2004

Correction: Individual Case Analysis of Postmortem Interval Time on Brain Tissue Preservation

artículo científico publicado en 2016

Correction: Prion Protein Protects against Renal Ischemia/Reperfusion Injury

artículo científico publicado en 2015

Curcumin/melatonin hybrid 5-(4-hydroxy-phenyl)-3-oxo-pentanoic acid [2-(5-methoxy-1H-indol-3-yl)-ethyl]-amide ameliorates AD-like pathology in the APP/PS1 mouse model

artículo científico publicado en 2015

DLP1-dependent mitochondrial fragmentation mediates 1-methyl-4-phenylpyridinium toxicity in neurons: implications for Parkinson's disease

artículo científico

Decline in mitochondrial bioenergetics underlies central insulin resistance in streptozocin-induced model of sporadic Alzheimer's disease

scholarly article by Sónia Correia et al published July 2011 in Alzheimer's and Dementia

Detection and localization of markers of oxidative stress by in situ methods: application in the study of Alzheimer disease

artículo científico publicado en 2010

Differential regulation of glutamate receptors in Alzheimer's disease

artículo científico publicado en 2002

Dissociated Aβ antibody level in newly diagnosed Alzheimer's disease: A population-based study

article

Distribution, levels and phosphorylation of Raf-1 in Alzheimer's disease

artículo científico publicado en 2006

Disturbance in AMP-activated protein kinase (AMPK) signaling pathway in Alzheimer's disease

Divalent metal transporter, iron, and Parkinson's disease: a pathological relationship.

artículo científico publicado en 2010

Down-regulation of aminolevulinate synthase, the rate-limiting enzyme for heme biosynthesis in Alzheimer's disease

artículo científico publicado en 2009

Down-regulation of serum gonadotropins but not estrogen replacement improves cognition in aged-ovariectomized 3xTg AD female mice

artículo científico publicado en 2014

Down-regulation of serum gonadotropins is as effective as estrogen replacement at improving menopause-associated cognitive deficits

artículo científico publicado en 2009

Dynamin-like protein 1 cleavage by calpain in Alzheimer's disease.

artículo científico publicado en 2019

Dynamin-like protein 1 reduction underlies mitochondrial morphology and distribution abnormalities in fibroblasts from sporadic Alzheimer's disease patients

artículo científico publicado en 2008

Dysregulation of leptin signaling in Alzheimer disease: evidence for neuronal leptin resistance

artículo científico publicado en 2013

Early induction of c-Myc is associated with neuronal cell death

artículo científico publicado en 2011

Early induction of oxidative stress in mouse model of Alzheimer disease with reduced mitochondrial superoxide dismutase activity

artículo científico publicado en 2012

Ectopic expression of phospho-Smad2 in Alzheimer's disease: uncoupling of the transforming growth factor-beta pathway?

artículo científico publicado en 2006

Ectopic localization of FOXO3a protein in Lewy bodies in Lewy body dementia and Parkinson's disease

scientific article published on 23 July 2009

Ectopic localization of phosphorylated histone H3 in Alzheimer's disease: a mitotic catastrophe?

artículo científico publicado en 2003

Elevated expression of a regulator of the G2/M phase of the cell cycle, neuronal CIP-1-associated regulator of cyclin B, in Alzheimer's disease

artículo científico publicado en 2004

Emerging evidence for the neuroprotective role of alpha-synuclein

artículo científico publicado en 2006

Estrogen receptor-α is localized to neurofibrillary tangles in Alzheimer's disease

artículo científico publicado en 2016

Evidence for Oxidative Damage in the Autistic Brain

article

Evidence of DNA damage in Alzheimer disease: phosphorylation of histone H2AX in astrocytes

artículo científico publicado en 2008

Expression of CD74 is increased in neurofibrillary tangles in Alzheimer's disease

artículo científico publicado en 2008

Ferric cycle activity and Alzheimer disease

artículo científico publicado en 2005

Frontiers in Alzheimer's disease therapeutics

artículo científico publicado en 2011

Genome-wide analysis of DNA methylation during antagonism of DMOG to MnCl2-induced cytotoxicity in the mouse substantia nigra

artículo científico publicado en 2016

Getting the iron out: phlebotomy for Alzheimer's disease?

artículo científico publicado en 2009

Glutaredoxin deficiency exacerbates neurodegeneration in C. elegans models of Parkinson's disease

artículo científico publicado en 2014

Glycogen synthase kinase 3: a point of integration in Alzheimer's disease and a therapeutic target?

artículo científico publicado en 2012

Heme catabolism and heme oxygenase in neurodegenerative disease

artículo científico publicado en 2004

Heme deficiency in Alzheimer's disease: a possible connection to porphyria

scientific article (publication date: 2006)

Heme-a, the heme prosthetic group of cytochrome c oxidase, is increased in Alzheimer's disease

scientific article published on 17 June 2009

Hibernation, a Model of Neuroprotection

High-resolution analytical imaging and electron holography of magnetite particles in amyloid cores of Alzheimer's disease

artículo científico publicado en 2016

Hydroxynonenal-generated crosslinking fluorophore accumulation in Alzheimer disease reveals a dichotomy of protein turnover

artículo científico publicado en 2011

Impaired balance of mitochondrial fission and fusion in Alzheimer's disease

scientific journal article

Impaired mitochondrial biogenesis contributes to mitochondrial dysfunction in Alzheimer's disease

artículo científico publicado en 2011

In Memoriam: Mark A. Smith, PhD

In Memoriam: Mark A. Smith, PhD: Neuroscientist and Visionary

In Vivo and In Silico Evidence: Hippocampal Cholesterol Metabolism Decreases with Aging and Increases with Alzheimers Disease -- Modeling Brain Aging and Disease

Increased expression of p130 in Alzheimer disease

artículo científico publicado en 2006

Increased iron and free radical generation in preclinical Alzheimer disease and mild cognitive impairment

artículo científico publicado en 2010

Increased isoprostane and prostaglandin are prominent in neurons in Alzheimer disease

artículo científico publicado en 2007

Increased p27, an essential component of cell cycle control, in Alzheimer's disease

artículo científico publicado en 2003

Individual Case Analysis of Postmortem Interval Time on Brain Tissue Preservation

artículo científico publicado en 2016

Indoleamine 2,3-dioxygenase and 3-hydroxykynurenine modifications are found in the neuropathology of Alzheimer's disease

artículo científico publicado en 2010

Inhibition of mitochondrial fragmentation protects against Alzheimer's disease in rodent model

artículo científico publicado en 2017

Insights into amyloid-beta-induced mitochondrial dysfunction in Alzheimer disease

artículo científico publicado en 2007

Insights into the Impact of a Membrane-Anchoring Moiety on the Biological Activities of Bivalent Compounds As Potential Neuroprotectants for Alzheimer's Disease

artículo científico publicado en 2017

Insulin and Insulin-Sensitizing Drugs in Neurodegeneration: Mitochondria as Therapeutic Targets

artículo científico publicado en 2009

Insulin is a two-edged knife on the brain

artículo científico publicado en 2009

Insulin signaling, diabetes mellitus and risk of Alzheimer disease.

artículo científico publicado en 2005

Insulin-resistant brain state: the culprit in sporadic Alzheimer's disease?

artículo científico publicado en 2011

Intraneuronal amyloid beta accumulation and oxidative damage to nucleic acids in Alzheimer disease

artículo científico publicado en 2009

Involvement of oxidative stress in Alzheimer disease

artículo científico publicado en 2006

Ionizing radiation causes increased tau phosphorylation in primary neurons

artículo científico publicado en 2014

Iron: A Pathological Mediator of Alzheimer Disease?

artículo científico publicado en 2009

Iron: the Redox-active center of oxidative stress in Alzheimer disease

artículo científico publicado en 2007

Is Alzheimer's disease a mitochondrial disorder?

artículo científico publicado en 2002

Is oxidative damage the fundamental pathogenic mechanism of Alzheimer's and other neurodegenerative diseases?

artículo científico publicado en 2002

JKK1, an upstream activator of JNK/SAPK, is activated in Alzheimer's disease

artículo científico publicado en 2003

Kinase inhibitors arrest neurodegeneration in cell and C. elegans models of LRRK2 toxicity

artículo científico publicado en 2012

LRRK2 in Parkinson's disease and dementia with Lewy bodies

artículo científico publicado en 2006

LRRK2 protein is a component of lewy bodies

LRRK2 regulates mitochondrial dynamics and function through direct interaction with DLP1

artículo científico publicado en 2012

LRRK2-mediated neurodegeneration and dysfunction of dopaminergic neurons in a Caenorhabditis elegans model of Parkinson's disease

artículo científico publicado en 2010

Leptin inhibits glycogen synthase kinase-3beta to prevent tau phosphorylation in neuronal cells

artículo científico publicado en 2009

Leptin reduces Alzheimer's disease-related tau phosphorylation in neuronal cells

artículo científico publicado en 2008

Leptin reduces pathology and improves memory in a transgenic mouse model of Alzheimer's disease

artículo científico publicado en 2010

Leptin: a novel therapeutic strategy for Alzheimer's disease

artículo científico publicado en 2009

Leucine-rich repeat kinase 2 colocalizes with alpha-synuclein in Parkinson's disease, but not tau-containing deposits in tauopathies

artículo científico publicado en 2008

Lipoic acid and N-acetyl cysteine decrease mitochondrial-related oxidative stress in Alzheimer disease patient fibroblasts.

artículo científico publicado en 2007

Lipoic acid and N-acetyl cysteine protect against mitochondrial-related oxidative stress in fibroblasts from Alzheimer disease patients

Luteinizing hormone downregulation but not estrogen replacement improves ovariectomy-associated cognition and spine density loss independently of treatment onset timing.

artículo científico publicado en 2015

MAPKs are differentially modulated in arctic ground squirrels during hibernation

artículo científico publicado en 2005

Mark A. Smith

Mark A. Smith, 1965-2010: consummate student of pathogenesis

artículo científico publicado en 2011

Mark A. Smith, PhD: Renegade Scientist and Visionary

Mark A. Smith: neurocytochemistry innovator

artículo científico publicado en 2012

Mark A. Smith: the scientist, the man.

artículo científico publicado en 2011

Mark Anthony Smith (1965-2010): Visionary, Alzheimer researcher, and editor-in-chief of the Journal of Alzheimer's Disease

artículo científico publicado en 2011

Mark Smith: Pioneer of Alzheimer Disease Research

Melatonin exhibits antioxidant properties in a mouse brain slice model of excitotoxicity

artículo científico publicado en 2002

Memantine: "hypothesis testing" not "disease modifying" in Alzheimer's disease

artículo científico publicado en 2009

Metal Homeostasis and Its Relation to Oxidative Stress in Alzheimer’s Disease

Mfn2 protects dopaminergic neurons exposed to paraquat both in vitro and in vivo: Implications for idiopathic Parkinson's disease

artículo científico publicado en 2017

Microbial origin of glutamate, hibernation and tissue trauma: an in vivo microdialysis study

artículo científico publicado en 2002

Microtubule Reduction in Alzheimer's Disease and Aging Is Independent of τ Filament Formation ⬇️

artículo científico publicado el 1 de mayo de 2003

Miro1 deficiency in amyotrophic lateral sclerosis

artículo científico publicado en 2015

Mislocalization of CDK11/PITSLRE, a regulator of the G2/M phase of the cell cycle, in Alzheimer disease

artículo científico publicado en 2011

Mitochondria and Neurodegenerative Diseases

Mitochondria: a therapeutic target in neurodegeneration

artículo científico publicado en 2009

Mitochondria: the missing link between preconditioning and neuroprotection

artículo científico publicado en 2010

Mitochondrial DNA oxidative damage and repair in aging and Alzheimer's disease

artículo científico publicado en 2012

Mitochondrial Drugs for Alzheimer Disease

artículo científico publicado en 2009

Mitochondrial abnormalities and oxidative imbalance in Alzheimer disease.

artículo científico publicado en 2006

Mitochondrial abnormalities and oxidative imbalance in neurodegenerative disease.

artículo científico publicado en 2002

Mitochondrial defects and oxidative stress in Alzheimer disease and Parkinson disease

artículo científico publicado en 2013

Mitochondrial dynamic abnormalities in amyotrophic lateral sclerosis

artículo científico publicado en 2015

Mitochondrial dynamics in Alzheimer's disease: opportunities for future treatment strategies

artículo científico publicado en 2010

Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology

scientific article published on 21 October 2009

Mitochondrial failures in Alzheimer's disease

artículo científico publicado en 2004

Mitochondrial importance in Alzheimer's, Huntington's and Parkinson's diseases

artículo científico

Mitochondrial preconditioning: a potential neuroprotective strategy

artículo científico publicado en 2010

Mitogen- and stress-activated protein kinase 1: convergence of the ERK and p38 pathways in Alzheimer's disease

artículo científico publicado en 2005

Modulation of Parkinson's Disease Associated Protein Rescues Alzheimer's Disease Degeneration

artículo científico publicado en 2016

Modulation of hippocampal plasticity and cognitive behavior by short-term blueberry supplementation in aged rats

artículo científico publicado en 2004

Molecular neuropathogenesis of Alzheimer's disease: an interaction model stressing the central role of oxidative stress

artículo científico publicado en 2012

Molecular pathogenesis of Alzheimer's disease: reductionist versus expansionist approaches

scientific article published on 26 March 2009

Mutant presenilin 1 increases the expression and activity of BACE1

artículo científico publicado en 2009

Nanoparticle and other metal chelation therapeutics in Alzheimer disease

artículo científico publicado en 2005

Nanoparticle delivery of transition-metal chelators to the brain: Oxidative stress will never see it coming!

artículo científico publicado en 2012

Natural Oxidant Balance in Parkinson Disease

scholarly article by George Perry et al published 1 December 2009 in Archives of Neurology

Neurodegenerative diseases: mechanisms and therapies

artículo científico publicado en 2006

Neurodegenerative processes in Alzheimer’s disease: an overview of pathogenesis with strategic biomarker potential

Neurofibrillary Tangle Formation as a Protective Response to Oxidative Stress in Alzheimer’s Disease

article

Neurofilamentopathy in neurodegenerative diseases

artículo científico

Neurogenesis in Alzheimer’s Disease

Neurogenesis in Human Hippocampus: Implications for Alzheimer Disease Pathogenesis

Neuronal Survival and Death in Alzheimer Disease

Neuronal failure in Alzheimer's disease: a view through the oxidative stress looking-glass

artículo científico publicado en 2014

Neuronal leptin resistance in Alzheimer's disease

scholarly article by David Bonda et al published July 2013 in Alzheimer's and Dementia

Neuropathology and treatment of Alzheimer disease: did we lose the forest for the trees?

artículo científico publicado en 2007

Neuropathology in Alzheimer's disease: awaking from a hundred-year-old dream

artículo científico publicado en 2006

Neuropathology of Alzheimer disease: pathognomonic but not pathogenic

artículo científico publicado en 2006

Neuroprotective effect of cocoa flavonoids on in vitro oxidative stress

artículo científico publicado en 2008

Neuroprotective effect of cocoa flavonoids on in vitro oxidative stress

Neuroprotective properties of Bcl-w in Alzheimer disease

artículo científico publicado en 2004

New Perspectives on Alzheimer's Disease and Nutrition

artículo científico

Novel therapeutics for Alzheimer's disease: an update

artículo científico publicado en 2010

Nuclear and mitochondrial DNA oxidation in Alzheimer's disease

artículo científico publicado en 2012

O2-04-07 Elevated expression of a regulator of the G2/M phase of the cell cycle, neuronal CIP-1 associated regulator of cyclin B, in Alzheimer disease

Oxidative Adaptation in Aging and Alzheimer’s Disease

Oxidative Damage and Antioxidant Responses in Alzheimer's Disease

article

Oxidative Stress and Alzheimer Disease: Mechanisms and Therapeutic Opportunities

Oxidative Stress and Balance in Neurodegenerative Diseases

Oxidative Stress and Neurodegeneration: An Inevitable Consequence of Aging? Implications for Therapy

article

Oxidative Stress and its Implications for Future Treatments and Management of Alzheimer Disease

artículo científico publicado en 2010

Oxidative Stress in Alzheimer’s Disease: A Critical Appraisal of the Causes and the Consequences

Oxidative Stress in Parkinson`s Disease

scholarly article by Avi L. Friedlich et al published 20 May 2009 in The open pathology journal

Oxidative damage and Alzheimer's disease: are antioxidant therapies useful?

artículo científico publicado en 2005

Oxidative damage to RNA in aging and neurodegenerative disorders

artículo científico

Oxidative damage to RNA in neurodegenerative diseases

artículo científico publicado en 2006

Oxidative imbalance in Alzheimer's disease

artículo científico publicado en 2005

Oxidative stress activates a positive feedback between the gamma- and beta-secretase cleavages of the beta-amyloid precursor protein ⬇️

artículo científico publicado en 2007

Oxidative stress and mitochondrial dysfunction in Alzheimer's disease

artículo científico publicado en 2013

Oxidative stress and neurodegeneration

artículo científico publicado en 2005

Oxidative stress and neuronal adaptation in Alzheimer disease: the role of SAPK pathways

artículo científico publicado en 2003

Oxidative stress in Alzheimer disease: a possibility for prevention

artículo científico publicado en 2010

Oxidative stress in diabetes and Alzheimer's disease

scientific article published on January 2009

Oxidative stress signalling in Alzheimer's disease

artículo científico publicado en 2004

Oxidative stress: the old enemy in Alzheimer's disease pathophysiology

artículo científico publicado en 2005

P1-266 The critical role of the ERK pathway in the pathogenesis of Alzheimer's disease

scholarly article by Xiongwei Zhu et al published July 2004 in Neurobiology of Aging

P1-351: A novel approach to diagnosis: Antigen-antibody disassociation in Alzheimer's disease

scholarly article by Mark A. Smith et al published July 2008 in Alzheimer's and Dementia

P3-219 Acetylation: a novel posttranslational modification in Alzheimer disease

P3-306 Differential expression of metabotrophic glutamate receptors (MGlurs) in Alzheimer disease

P3-317: Failure in the control of cell cycle causes neurodegeneration

P3-375

P38 activation mediates amyloid-beta cytotoxicity

artículo científico publicado en 2005

P4-162

P4-166: Overexpression of amyloid precursor protein causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins

PKC inhibition is involved in trichosanthin-induced apoptosis in human chronic myeloid leukemia cell line K562.

artículo científico publicado en 2006

Parkinson's disease-associated DJ-1 mutations impair mitochondrial dynamics and cause mitochondrial dysfunction

artículo científico publicado en 2012

Parkinson's disease-associated pathogenic VPS35 mutation causes complex I deficits

artículo científico publicado en 2017

Pathological implications of cell cycle re-entry in Alzheimer disease

artículo científico publicado en 2010

Pathological phenotype in familial neurodegenerative disease: implications for families and therapeutic constructs

Pathology's new role: defining disease process and protective responses.

artículo científico publicado en 2008

Perspectives on the amyloid-beta cascade hypothesis

artículo científico publicado en 2004

Phosphorylation of tau protein as the link between oxidative stress, mitochondrial dysfunction, and connectivity failure: implications for Alzheimer's disease

artículo científico publicado en 2013

Physiological regulation of tau phosphorylation during hibernation

artículo científico publicado en 2008

Posttranslational modifications of α-tubulin in alzheimer disease

artículo científico publicado en 2015

Presenilin mutation: a deadly first hit in Alzheimer disease. A commentary on "aging sensitizes towards ROS formation and lipid peroxidation in PS1M146L transgenic mice".

artículo científico publicado en 2006

Presenilin mutations impair mitochondrial dynamics in neurons

Prevention and treatment of Alzheimer disease and aging: antioxidants

artículo científico publicado en 2007

Prion Protein Protects against Renal Ischemia/Reperfusion Injury

artículo científico publicado en 2015

Probing and trapping a sensitive conformation: amyloid-β fibrils, oligomers, and dimers

artículo científico publicado en 2012

Protein Misfolding in Alzheimer's Disease

scholarly article published 3 December 2007

R-_-Lipoic Acid as a Potent Agent of Mitochondrial Protectionin Alzheimer’s Disease

Redox Active Iron at the Center of Oxidative Stress in Alzheimer Disease

article published in 2005

Reexamining Alzheimer's disease: evidence for a protective role for amyloid-beta protein precursor and amyloid-beta

artículo científico publicado en 2009

Regulation of DJ-1 by Glutaredoxin 1 in Vivo: Implications for Parkinson's Disease

artículo científico publicado en 2016

Retinoblastoma protein phosphorylation at multiple sites is associated with neurofibrillary pathology in Alzheimer disease.

artículo científico publicado en 2008

Ribosomal RNA in Alzheimer disease is oxidized by bound redox-active iron

artículo científico publicado en 2005

Role of Oxidative Insult and Neuronal Survival in Alzheimer’s and Parkinson’s Diseases

scholarly article

Role of metal dyshomeostasis in Alzheimer's disease

artículo científico publicado en 2011

Role of mitochondrial-mediated signaling pathways in Alzheimer disease and hypoxia

artículo científico publicado en 2009

S4-02-01 Alzheimer disease: the two hit hypothesis

Sequestration of p27 within the cytoplasm of cardiac myocytes in chronic ischemic heart disease: pathogenic implications for ischemic cardiomyopathy

artículo científico publicado en 2006

Signal Transduction in Alzheimer’s Disease

article published in 2002

Signal transduction cascades associated with oxidative stress in Alzheimer's disease

artículo científico publicado en 2007

Signaling effect of amyloid-beta(42) on the processing of AbetaPP

artículo científico publicado en 2010

Staying connected: synapses in Alzheimer disease

artículo científico publicado en 2004

Steroidogenic acute regulatory protein (StAR): evidence of gonadotropin-induced steroidogenesis in Alzheimer disease

artículo científico publicado en 2006

Tau modifiers as therapeutic targets for Alzheimer's disease

artículo científico publicado en 2005

Tau phosphorylation in Alzheimer's disease: pathogen or protector?

artículo científico publicado en 2005

Tau--an inhibitor of deacetylase HDAC6 function

artículo científico publicado en 2009

The (un)balance between metabolic and oxidative abnormalities and cellular compensatory responses in Alzheimer disease

artículo científico publicado en 2006

The Key Role of Oxidative Stress in Alzheimer's Disease

scholarly article published 2007

The Potential Application of Antioxidant Agents in Alzheimer Disease Therapeutics

The cell cycle and hormonal fluxes in Alzheimer disease: a novel therapeutic target

artículo científico publicado en 2006

The cell cycle in Alzheimer disease: a unique target for neuropharmacology

artículo científico publicado en 2005

The cell cycle regulator phosphorylated retinoblastoma protein is associated with tau pathology in several tauopathies

artículo científico publicado en 2011

The concept of redox balance in Alzheimer's disease: Mark Anthony Smith 1965–2010

scholarly article by Xiongwei Zhu et al published March 2011 in Redox Report

The earliest stage of cognitive impairment in transition from normal aging to Alzheimer disease is marked by prominent RNA oxidation in vulnerable neurons

artículo científico publicado en 2012

The effect of mGluR2 activation on signal transduction pathways and neuronal cell survival

artículo científico publicado en 2008

The essential role of ERK in 4-oxo-2-nonenal-mediated cytotoxicity in SH-SY5Y human neuroblastoma cells

artículo científico publicado en 2009

The fallacy of amyloid and cognition in Alzheimer's disease

artículo científico publicado en 2006

The mitochondrial dynamics of Alzheimer's disease and Parkinson's disease offer important opportunities for therapeutic intervention

artículo científico publicado en 2011

The neuronal expression of MYC causes a neurodegenerative phenotype in a novel transgenic mouse

artículo científico publicado en 2009

The origin of oxidative stress in neurodegenerative disease: Mark Anthony Smith 1965–2010

The p38 pathway is activated in Pick disease and progressive supranuclear palsy: a mechanistic link between mitogenic pathways, oxidative stress, and tau.

artículo científico publicado en 2002

The role of E2F1 in the development of hypertrophic cardiomyopathy

artículo científico publicado en 2011

The role of abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease

artículo científico publicado en 2009

The role of iron as a mediator of oxidative stress in Alzheimer disease

artículo científico

The role of mitogen-activated protein kinase pathways in Alzheimer's disease

artículo científico publicado en 2002

The rs3756063 polymorphism is associated with SNCA methylation in the Chinese Han population

artículo científico publicado en 2016

The sirtuin pathway in ageing and Alzheimer disease: mechanistic and therapeutic considerations

artículo científico publicado en 2011

Therapeutic opportunities in Alzheimer disease: one for all or all for one?

artículo científico publicado en 2005

Therapeutic options in Alzheimer's disease

artículo científico publicado en 2006

Therapeutic potential of oxidant mechanisms in Alzheimer's disease

artículo científico publicado en 2004

Thinking Outside the Box in Alzheimer Disease Treatment

Tipping the apoptotic balance in Alzheimer's disease: the abortosis concept

artículo científico publicado en 2003

Transcriptome-To-Metabolome™ Biosimulation Reveals Human Hippocampal Hypometabolism with Age and Alzheimer’s Disease

Treating the lesions, not the disease

artículo científico publicado en 2007

Treatment advances in Alzheimer's disease based on the oxidative stress model

artículo científico publicado en 2009

Two Hits and You’re Out? A Novel Mechanistic Hypothesis of Alzheimer Disease

Untangling the vascular web from Alzheimer disease and oxidative stress.

artículo científico publicado en 2012

Vascular oxidative stress in Alzheimer disease

artículo científico publicado en 2007

Widespread distribution of reticulon-3 in various neurodegenerative diseases

artículo científico publicado en 2010

Will Preventing Protein Aggregates Live Up to Its Promise as Prophylaxis Against Neurodegenerative Diseases?

article

Will preventing protein aggregates live up to its promise as prophylaxis against neurodegenerative diseases?

artículo científico publicado en 2003

c-Jun phosphorylation in Alzheimer disease

artículo científico publicado en 2007

eIF2alpha phosphorylation tips the balance to apoptosis during osmotic stress

artículo científico publicado en 2010

Dominio Público Uruguay está sostenido por:

Acerca de Dominio Público Uruguay

Ayuda