Lista de obras -

A Chimeric Plasmodium falciparum Merozoite Surface Protein Vaccine Induces High Titers of Parasite Growth Inhibitory Antibodies ⬇️

artículo científico publicado el 29 de julio de 2013

A PfRH5-based vaccine is efficacious against heterologous strain blood-stage Plasmodium falciparum infection in aotus monkeys

artículo científico publicado en 2015

A Phase 1 study of the blood-stage malaria vaccine candidate AMA1-C1/Alhydrogel with CPG 7909, using two different formulations and dosing intervals

artículo científico publicado en 2009

A class of tricyclic compounds blocking malaria parasite oocyst development and transmission

artículo científico publicado en 2012

A glycoprotein from Spirometra erinaceieuropaei plerocercoids suppresses osteoclastogenesis and proinflammatory cytokine gene expression

artículo científico publicado en 2005

A malaria vaccine adjuvant based on recombinant antigen binding to liposomes

scientific article published on 08 October 2018

A malaria vaccine protects Aotus monkeys against virulent Plasmodium falciparum infection

artículo científico

A randomized and controlled Phase 1 study of the safety and immunogenicity of the AMA1-C1/Alhydrogel + CPG 7909 vaccine for Plasmodium falciparum malaria in semi-immune Malian adults

artículo científico publicado en 2009

A randomized controlled phase 2 trial of the blood stage AMA1-C1/Alhydrogel malaria vaccine in children in Mali

artículo científico publicado en 2009

A slot blot immunoassay for quantitative detection of Plasmodium falciparum circumsporozoite protein in mosquito midgut oocyst

artículo científico publicado en 2014

An N-terminal Pfs230 domain produced in baculovirus as a biological active transmission-blocking vaccine candidate

artículo científico publicado en 2017

An inter-laboratory comparison of standard membrane-feeding assays for evaluation of malaria transmission-blocking vaccines

artículo científico publicado en 2016

Anaemia in a phase 2 study of a blood stage falciparum malaria vaccine

artículo científico publicado en 2011

Analysis of the conformation and function of the Plasmodium falciparum merozoite proteins MTRAP and PTRAMP

artículo científico publicado en 2012

Anti-apical-membrane-antigen-1 antibody is more effective than anti-42-kilodalton-merozoite-surface-protein-1 antibody in inhibiting plasmodium falciparum growth, as determined by the in vitro growth inhibition assay

artículo científico publicado en 2009

Antigen reversal identifies targets of opsonizing IgGs against pregnancy-associated malaria

artículo científico publicado en 2014

Assessment of Antibodies Induced by Multivalent Transmission-Blocking Malaria Vaccines

artículo científico publicado en 2017

Assessment of Pfs25 expressed from multiple soluble expression platforms for use as transmission-blocking vaccine candidates

artículo científico publicado en 2016

Assessment of humoral immune responses to blood-stage malaria antigens following ChAd63-MVA immunization, controlled human malaria infection and natural exposure

artículo científico publicado en 2014

ChAd63-MVA-vectored blood-stage malaria vaccines targeting MSP1 and AMA1: assessment of efficacy against mosquito bite challenge in humans

artículo científico publicado en 2012

Changes in Serological Immunology Measures in UK and Kenyan Adults Post-controlled Human Malaria Infection

artículo científico publicado en 2016

Combination of RTS,S and Pfs25-IMX313 Induces a Functional Antibody Response Against Malaria Infection and Transmission in Mice

article

Combining viral vectored and protein-in-adjuvant vaccines against the blood-stage malaria antigen AMA1: report on a phase 1a clinical trial

artículo científico publicado en 2014

Comparative assessment of An. gambiae and An. stephensi mosquitoes to determine transmission-reducing activity of antibodies against P. falciparum sexual stage antigens

artículo científico publicado en 2017

Comparison of biological activity of human anti-apical membrane antigen-1 antibodies induced by natural infection and vaccination

scientific article published on December 2008

Correction: Overcoming Antigenic Diversity by Enhancing the Immunogenicity of Conserved Epitopes on the Malaria Vaccine Candidate Apical Membrane Antigen-1.

artículo científico publicado en 2014

Development and characterization of a standardized ELISA including a reference serum on each plate to detect antibodies induced by experimental malaria vaccines

artículo científico publicado en 2007

Discovery of GAMA, a Plasmodium falciparum merozoite micronemal protein, as a novel blood-stage vaccine candidate antigen

artículo científico publicado en 2011

Effect of ingested human antibodies induced by RTS, S/AS01 malaria vaccination in children on Plasmodium falciparum oocyst formation and sporogony in mosquitoes

artículo científico publicado en 2014

Effect of red blood cell variants on childhood malaria in Mali: a prospective cohort study

artículo científico publicado en 2015

Effects of age, hemoglobin type and parasite strain on IgG recognition of Plasmodium falciparum-infected erythrocytes in Malian children

artículo científico publicado en 2013

Enhancing blockade of Plasmodium falciparum erythrocyte invasion: assessing combinations of antibodies against PfRH5 and other merozoite antigens ⬇️

artículo científico publicado en 2012

Enhancing immunogenicity and transmission-blocking activity of malaria vaccines by fusing Pfs25 to IMX313 multimerization technology

artículo científico publicado en 2016

Erratum: Corrigendum: The blood-stage malaria antigen PfRH5 is susceptible to vaccine-inducible cross-strain neutralizing antibody

artículo científico publicado en 2013

Evaluation of a Plasmodium-specific carrier protein to enhance production of recombinant Pfs25, a leading transmission-blocking vaccine candidate

artículo científico publicado en 2017

Expression of full-length Plasmodium falciparum P48/45 in P. berghei blood stages: A method to express and evaluate vaccine antigens

article by Ahmad Syibli Othman et al published 24 July 2018 in Molecular and Biochemical Parasitology

Functional Analysis Reveals Geographical Variation in Inhibitory Immune Responses Against a Polymorphic Malaria Antigen

artículo científico publicado en 2017

Functional comparison of Plasmodium falciparum transmission-blocking vaccine candidates by the standard membrane-feeding assay

artículo científico publicado en 2013

Hematological Indices in Malian Children Change Significantly During a Malaria Season and with Increasing Age: Implications for Malaria Epidemiological Studies

artículo científico publicado en 2016

High Plasmodium falciparum longitudinal prevalence is associated with high multiclonality and reduced clinical malaria risk in a seasonal transmission area of Mali

artículo científico publicado en 2017

Host age and Plasmodium falciparum multiclonality are associated with gametocyte prevalence: a 1-year prospective cohort study.

artículo científico publicado en 2017

Identification of target proteins of clinical immunity to Plasmodium falciparum in a region of low malaria transmission

artículo científico publicado en 2017

Immune characterization of Plasmodium falciparum parasites with a shared genetic signature in a region of decreasing transmission

artículo científico publicado en 2014

Immunisation against a serine protease inhibitor reduces intensity of Plasmodium berghei infection in mosquitoes

artículo científico publicado en 2013

Immunity to recombinant plasmodium falciparum merozoite surface protein 1 (MSP1): protection in Aotus nancymai monkeys strongly correlates with anti-MSP1 antibody titer and in vitro parasite-inhibitory activity

artículo científico publicado en 2006

Immunization with a functional protein complex required for erythrocyte invasion protects against lethal malaria

artículo científico publicado en 2014

Immunogenicity of a chimeric Plasmodium falciparum merozoite surface protein vaccine in Aotus monkeys

artículo científico publicado en 2016

Immunological responses against Plasmodium falciparum Apical Membrane Antigen 1 vaccines vary depending on the population immunized

artículo científico publicado en 2011

Immunoscreening of Plasmodium falciparum proteins expressed in a wheat germ cell-free system reveals a novel malaria vaccine candidate

artículo científico publicado en 2017

Impact of a Plasmodium falciparum AMA1 vaccine on antibody responses in adult Malians

artículo científico publicado en 2007

Impact on malaria parasite multiplication rates in infected volunteers of the protein-in-adjuvant vaccine AMA1-C1/Alhydrogel+CPG 7909.

artículo científico publicado en 2011

Improving malaria control in West Africa: interruption of transmission as a paradigm shift

artículo científico publicado en 2011

In immunization with Plasmodium falciparum apical membrane antigen 1, the specificity of antibodies depends on the species immunized

artículo científico publicado en 2007

In vitro growth-inhibitory activity and malaria risk in a cohort study in mali

artículo científico publicado en 2009

Macrophage migration inhibitory factor homolog from Plasmodium yoelii modulates monocyte recruitment and activation in spleen during infection

artículo científico publicado en 2011

Malaria Derived Glycosylphosphatidylinositol Anchor Enhances Anti-Pfs25 Functional Antibodies That Block Malaria Transmission

artículo científico publicado en 2018

Measuring precision in bioassays: Rethinking assay validation

artículo científico publicado en 2017

Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25.

artículo científico publicado en 2017

Multiple pathways for Plasmodium ookinete invasion of the mosquito midgut

artículo científico publicado en 2014

Nanoassembly routes stimulate conflicting antibody quantity and quality for transmission-blocking malaria vaccines

artículo científico publicado en 2017

Naturally acquired antibodies specific for Plasmodium falciparum reticulocyte-binding protein homologue 5 inhibit parasite growth and predict protection from malaria

artículo científico publicado en 2013

New adenovirus-based vaccine vectors targeting Pfs25 elicit antibodies that inhibit Plasmodium falciparum transmission

artículo científico publicado en 2017

Non-Apical Membrane Antigen 1 (AMA1) IgGs from Malian Children Interfere with Functional Activity of AMA1 IgGs as Judged by Growth Inhibition Assay ⬇️

artículo científico publicado el 13 de junio de 2011

Overcoming allelic specificity by immunization with five allelic forms of Plasmodium falciparum apical membrane antigen 1.

artículo científico publicado en 2013

Overcoming antigenic diversity by enhancing the immunogenicity of conserved epitopes on the malaria vaccine candidate apical membrane antigen-1.

artículo científico publicado en 2013

Phase 1 safety and immunogenicity trial of the Plasmodium falciparum blood-stage malaria vaccine AMA1-C1/ISA 720 in Australian adults

artículo científico publicado en 2010

Phase 1 study in malaria naïve adults of BSAM2/Alhydrogel®+CPG 7909, a blood stage vaccine against P. falciparum malaria

artículo científico publicado en 2012

Phase 1 study of a combination AMA1 blood stage malaria vaccine in Malian children

artículo científico publicado en 2008

Phase 1 trial of AMA1-C1/Alhydrogel plus CPG 7909: an asexual blood-stage vaccine for Plasmodium falciparum malaria

artículo científico publicado en 2008

Phase 1 trial of malaria transmission blocking vaccine candidates Pfs25 and Pvs25 formulated with montanide ISA 51.

artículo científico publicado en 2008

Phase 1 trial of the Plasmodium falciparum blood stage vaccine MSP1(42)-C1/Alhydrogel with and without CPG 7909 in malaria naïve adults

artículo científico publicado en 2010

Phase 1 vaccine trial of Pvs25H: a transmission blocking vaccine for Plasmodium vivax malaria

artículo científico publicado en 2005

Phase Ia clinical evaluation of the Plasmodium falciparum blood-stage antigen MSP1 in ChAd63 and MVA vaccine vectors

artículo científico publicado en 2011

Phase Ia clinical evaluation of the safety and immunogenicity of the Plasmodium falciparum blood-stage antigen AMA1 in ChAd63 and MVA vaccine vectors

artículo científico publicado en 2012

Plasmodium falciparum merozoite surface protein 1 blocks the proinflammatory protein S100P

artículo científico publicado en 2012

Population structure of the genes encoding the polymorphic Plasmodium falciparum apical membrane antigen 1: implications for vaccine design

artículo científico publicado en 2008

Progress and prospects for blood-stage malaria vaccines

artículo científico publicado en 2016

Qualification of standard membrane-feeding assay with Plasmodium falciparum malaria and potential improvements for future assays

artículo científico publicado en 2013

RALP1 is a rhoptry neck erythrocyte-binding protein of Plasmodium falciparum merozoites and a potential blood-stage vaccine candidate antigen

artículo científico publicado en 2013

Relationship between Malaria Incidence and IgG Levels to Plasmodium falciparum Merozoite Antigens in Malian Children: Impact of Hemoglobins S and C ⬇️

artículo científico publicado el 28 de marzo de 2013

Safety and immunogenicity of a plant-produced Pfs25 virus-like particle as a transmission blocking vaccine against malaria: A Phase 1 dose-escalation study in healthy adults

article

Standardization of the antibody-dependent respiratory burst assay with human neutrophils and Plasmodium falciparum malaria

artículo científico publicado en 2015

Strong concordance between percent inhibition in oocyst and sporozoite intensities in a Plasmodium falciparum standard membrane-feeding assay

scholarly article published by Kazutoyo Miura in 2019

Structural basis for recognition of the malaria vaccine candidate Pfs48/45 by a transmission blocking antibody

artículo científico publicado en 2018

Structural delineation of potent transmission-blocking epitope I on malaria antigen Pfs48/45

artículo científico publicado en 2018

Subdomain 3 of Plasmodium falciparum VAR2CSA DBL3x is identified as a minimal chondroitin sulfate A-binding region

artículo científico publicado en 2010

Supergenomic network compression and the discovery of EXP1 as a glutathione transferase inhibited by artesunate

artículo científico publicado en 2014

Suppression of IP-10/CXCL10 gene expression in LPS- and/or IFN-γ-stimulated macrophages by parasite-secreted products

artículo científico publicado en 2012

TLR-adjuvanted nanoparticle vaccines differentially influence the quality and longevity of responses to malaria antigen Pfs25.

artículo científico publicado en 2018

The IC(50) of anti-Pfs25 antibody in membrane-feeding assay varies among species

artículo científico publicado en 2010

The Plasmodium falciparum-specific human memory B cell compartment expands gradually with repeated malaria infections

artículo científico publicado en 2010

The S. aureus 4-oxalocrotonate tautomerase SAR1376 enhances immune responses when fused to several antigens

artículo científico publicado en 2017

The TLR9 agonist CpG fails to enhance the acquisition of Plasmodium falciparum-specific memory B cells in semi-immune adults in Mali

artículo científico publicado en 2009

The TLR9 ligand CpG promotes the acquisition of Plasmodium falciparum-specific memory B cells in malaria-naive individuals

artículo científico publicado en 2009

The blood-stage malaria antigen PfRH5 is susceptible to vaccine-inducible cross-strain neutralizing antibody

artículo científico publicado en 2011

The heme biosynthesis pathway is essential for Plasmodium falciparum development in mosquito stage but not in blood stages

artículo científico publicado en 2014

Transmission-blocking activity induced by malaria vaccine candidates Pfs25/Pvs25 is a direct and predictable function of antibody titer

artículo científico publicado en 2007

Transmission-blocking activity is determined by transmission-reducing activity and number of control oocysts in Plasmodium falciparum standard membrane-feeding assay

artículo científico publicado en 2016

Vaccination with conserved regions of erythrocyte-binding antigens induces neutralizing antibodies against multiple strains of Plasmodium falciparum

artículo científico publicado en 2013

Vaccine design via nonnegative lasso-based variable selection

artículo científico publicado en 2015

What goes around comes around: modeling malaria transmission from humans back to mosquitos.

artículo científico publicado en 2018

posttranslational modification of recombinant Plasmodium falciparum apical membrane antigen 1: impact on functional immune responses to a malaria vaccine candidate

artículo científico publicado en 2005

Lista de obras de

A Chimeric Plasmodium falciparum Merozoite Surface Protein Vaccine Induces High Titers of Parasite Growth Inhibitory Antibodies ⬇️

A PfRH5-based vaccine is efficacious against heterologous strain blood-stage Plasmodium falciparum infection in aotus monkeys

A Phase 1 study of the blood-stage malaria vaccine candidate AMA1-C1/Alhydrogel with CPG 7909, using two different formulations and dosing intervals

A class of tricyclic compounds blocking malaria parasite oocyst development and transmission

A glycoprotein from Spirometra erinaceieuropaei plerocercoids suppresses osteoclastogenesis and proinflammatory cytokine gene expression

A malaria vaccine adjuvant based on recombinant antigen binding to liposomes

A malaria vaccine protects Aotus monkeys against virulent Plasmodium falciparum infection

A randomized and controlled Phase 1 study of the safety and immunogenicity of the AMA1-C1/Alhydrogel + CPG 7909 vaccine for Plasmodium falciparum malaria in semi-immune Malian adults

A randomized controlled phase 2 trial of the blood stage AMA1-C1/Alhydrogel malaria vaccine in children in Mali

A slot blot immunoassay for quantitative detection of Plasmodium falciparum circumsporozoite protein in mosquito midgut oocyst

An N-terminal Pfs230 domain produced in baculovirus as a biological active transmission-blocking vaccine candidate

An inter-laboratory comparison of standard membrane-feeding assays for evaluation of malaria transmission-blocking vaccines

Anaemia in a phase 2 study of a blood stage falciparum malaria vaccine

Analysis of the conformation and function of the Plasmodium falciparum merozoite proteins MTRAP and PTRAMP

Anti-apical-membrane-antigen-1 antibody is more effective than anti-42-kilodalton-merozoite-surface-protein-1 antibody in inhibiting plasmodium falciparum growth, as determined by the in vitro growth inhibition assay

Antigen reversal identifies targets of opsonizing IgGs against pregnancy-associated malaria

Assessment of Antibodies Induced by Multivalent Transmission-Blocking Malaria Vaccines

Assessment of Pfs25 expressed from multiple soluble expression platforms for use as transmission-blocking vaccine candidates

Assessment of humoral immune responses to blood-stage malaria antigens following ChAd63-MVA immunization, controlled human malaria infection and natural exposure

ChAd63-MVA-vectored blood-stage malaria vaccines targeting MSP1 and AMA1: assessment of efficacy against mosquito bite challenge in humans

Changes in Serological Immunology Measures in UK and Kenyan Adults Post-controlled Human Malaria Infection

Combination of RTS,S and Pfs25-IMX313 Induces a Functional Antibody Response Against Malaria Infection and Transmission in Mice

Combining viral vectored and protein-in-adjuvant vaccines against the blood-stage malaria antigen AMA1: report on a phase 1a clinical trial

Comparative assessment of An. gambiae and An. stephensi mosquitoes to determine transmission-reducing activity of antibodies against P. falciparum sexual stage antigens

Comparison of biological activity of human anti-apical membrane antigen-1 antibodies induced by natural infection and vaccination

Correction: Overcoming Antigenic Diversity by Enhancing the Immunogenicity of Conserved Epitopes on the Malaria Vaccine Candidate Apical Membrane Antigen-1.

Development and characterization of a standardized ELISA including a reference serum on each plate to detect antibodies induced by experimental malaria vaccines

Discovery of GAMA, a Plasmodium falciparum merozoite micronemal protein, as a novel blood-stage vaccine candidate antigen

Effect of ingested human antibodies induced by RTS, S/AS01 malaria vaccination in children on Plasmodium falciparum oocyst formation and sporogony in mosquitoes

Effect of red blood cell variants on childhood malaria in Mali: a prospective cohort study

Effects of age, hemoglobin type and parasite strain on IgG recognition of Plasmodium falciparum-infected erythrocytes in Malian children

Enhancing blockade of Plasmodium falciparum erythrocyte invasion: assessing combinations of antibodies against PfRH5 and other merozoite antigens ⬇️

Enhancing immunogenicity and transmission-blocking activity of malaria vaccines by fusing Pfs25 to IMX313 multimerization technology

Erratum: Corrigendum: The blood-stage malaria antigen PfRH5 is susceptible to vaccine-inducible cross-strain neutralizing antibody

Evaluation of a Plasmodium-specific carrier protein to enhance production of recombinant Pfs25, a leading transmission-blocking vaccine candidate

Expression of full-length Plasmodium falciparum P48/45 in P. berghei blood stages: A method to express and evaluate vaccine antigens

Functional Analysis Reveals Geographical Variation in Inhibitory Immune Responses Against a Polymorphic Malaria Antigen

Functional comparison of Plasmodium falciparum transmission-blocking vaccine candidates by the standard membrane-feeding assay

Hematological Indices in Malian Children Change Significantly During a Malaria Season and with Increasing Age: Implications for Malaria Epidemiological Studies

High Plasmodium falciparum longitudinal prevalence is associated with high multiclonality and reduced clinical malaria risk in a seasonal transmission area of Mali

Host age and Plasmodium falciparum multiclonality are associated with gametocyte prevalence: a 1-year prospective cohort study.

Identification of target proteins of clinical immunity to Plasmodium falciparum in a region of low malaria transmission

Immune characterization of Plasmodium falciparum parasites with a shared genetic signature in a region of decreasing transmission

Immunisation against a serine protease inhibitor reduces intensity of Plasmodium berghei infection in mosquitoes

Immunity to recombinant plasmodium falciparum merozoite surface protein 1 (MSP1): protection in Aotus nancymai monkeys strongly correlates with anti-MSP1 antibody titer and in vitro parasite-inhibitory activity

Immunization with a functional protein complex required for erythrocyte invasion protects against lethal malaria

Immunogenicity of a chimeric Plasmodium falciparum merozoite surface protein vaccine in Aotus monkeys

Immunological responses against Plasmodium falciparum Apical Membrane Antigen 1 vaccines vary depending on the population immunized

Immunoscreening of Plasmodium falciparum proteins expressed in a wheat germ cell-free system reveals a novel malaria vaccine candidate

Impact of a Plasmodium falciparum AMA1 vaccine on antibody responses in adult Malians

Impact on malaria parasite multiplication rates in infected volunteers of the protein-in-adjuvant vaccine AMA1-C1/Alhydrogel+CPG 7909.

Improving malaria control in West Africa: interruption of transmission as a paradigm shift

In immunization with Plasmodium falciparum apical membrane antigen 1, the specificity of antibodies depends on the species immunized

In vitro growth-inhibitory activity and malaria risk in a cohort study in mali

Macrophage migration inhibitory factor homolog from Plasmodium yoelii modulates monocyte recruitment and activation in spleen during infection

Malaria Derived Glycosylphosphatidylinositol Anchor Enhances Anti-Pfs25 Functional Antibodies That Block Malaria Transmission

Measuring precision in bioassays: Rethinking assay validation

Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25.

Multiple pathways for Plasmodium ookinete invasion of the mosquito midgut

Nanoassembly routes stimulate conflicting antibody quantity and quality for transmission-blocking malaria vaccines

Naturally acquired antibodies specific for Plasmodium falciparum reticulocyte-binding protein homologue 5 inhibit parasite growth and predict protection from malaria

New adenovirus-based vaccine vectors targeting Pfs25 elicit antibodies that inhibit Plasmodium falciparum transmission

Non-Apical Membrane Antigen 1 (AMA1) IgGs from Malian Children Interfere with Functional Activity of AMA1 IgGs as Judged by Growth Inhibition Assay ⬇️

Overcoming allelic specificity by immunization with five allelic forms of Plasmodium falciparum apical membrane antigen 1.

Overcoming antigenic diversity by enhancing the immunogenicity of conserved epitopes on the malaria vaccine candidate apical membrane antigen-1.

Phase 1 safety and immunogenicity trial of the Plasmodium falciparum blood-stage malaria vaccine AMA1-C1/ISA 720 in Australian adults

Phase 1 study in malaria naïve adults of BSAM2/Alhydrogel®+CPG 7909, a blood stage vaccine against P. falciparum malaria

Phase 1 study of a combination AMA1 blood stage malaria vaccine in Malian children

Phase 1 trial of AMA1-C1/Alhydrogel plus CPG 7909: an asexual blood-stage vaccine for Plasmodium falciparum malaria

Phase 1 trial of malaria transmission blocking vaccine candidates Pfs25 and Pvs25 formulated with montanide ISA 51.

Phase 1 trial of the Plasmodium falciparum blood stage vaccine MSP1(42)-C1/Alhydrogel with and without CPG 7909 in malaria naïve adults

Phase 1 vaccine trial of Pvs25H: a transmission blocking vaccine for Plasmodium vivax malaria

Phase Ia clinical evaluation of the Plasmodium falciparum blood-stage antigen MSP1 in ChAd63 and MVA vaccine vectors

Phase Ia clinical evaluation of the safety and immunogenicity of the Plasmodium falciparum blood-stage antigen AMA1 in ChAd63 and MVA vaccine vectors

Plasmodium falciparum merozoite surface protein 1 blocks the proinflammatory protein S100P

Population structure of the genes encoding the polymorphic Plasmodium falciparum apical membrane antigen 1: implications for vaccine design

Progress and prospects for blood-stage malaria vaccines

Qualification of standard membrane-feeding assay with Plasmodium falciparum malaria and potential improvements for future assays

RALP1 is a rhoptry neck erythrocyte-binding protein of Plasmodium falciparum merozoites and a potential blood-stage vaccine candidate antigen