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A Role for Fc Function in Therapeutic Monoclonal Antibody-Mediated Protection against Ebola Virus

scientific article published on 01 August 2018

A Single Dose Respiratory Recombinant Adenovirus-Based Vaccine Provides Long-Term Protection for Non-Human Primates from Lethal Ebola Infection

artículo científico publicado en 2014

A Two-Antibody Pan-Ebolavirus Cocktail Confers Broad Therapeutic Protection in Ferrets and Nonhuman Primates

scientific article published in 2019

Adenovirus-Vectored Vaccine Provides Postexposure Protection to Ebola Virus-Infected Nonhuman Primates

artículo científico publicado en 2015

An Adenovirus Vaccine Expressing Ebola Virus Variant Makona Glycoprotein Is Efficacious in Guinea Pigs and Nonhuman Primates

artículo científico publicado en 2016

Analysis of the expressed heavy chain variable-region genes of Macaca fascicularis and isolation of monoclonal antibodies specific for the Ebola virus' soluble glycoprotein

artículo científico publicado en 2005

Antibodies from a Human Survivor Define Sites of Vulnerability for Broad Protection against Ebolaviruses.

artículo científico publicado en 2017

Antibody Treatment of Ebola and Sudan Virus Infection via a Uniquely Exposed Epitope within the Glycoprotein Receptor-Binding Site

artículo científico publicado en 2016

Antibody therapeutics for Ebola virus disease

artículo científico publicado en 2016

Antibody therapy for Ebola: is the tide turning around?

artículo científico publicado en 2014

Antiviral activity of quercetin-3-β-O-D-glucoside against Zika virus infection.

artículo científico publicado en 2017

Assessing Antiviral Countermeasures Using Mouse Models of Ebolavirus Infection

artículo científico publicado en 2017

Assessment of the potential for host-targeted iminosugars UV-4 and UV-5 activity against filovirus infections in vitro and in vivo

artículo científico publicado en 2016

Can Ebola virus become endemic in the human population?

artículo científico publicado en 2015

Cellular-Beacon-Mediated Counting for the Ultrasensitive Detection of Ebola Virus on an Integrated Micromagnetic Platform

artículo científico publicado en 2018

Characterization of Reston virus infection in ferrets

scientific article published on 02 March 2019

Characterization of Sudan Ebolavirus infection in ferrets

artículo científico publicado en 2017

Characterization of Zaire ebolavirus glycoprotein-specific monoclonal antibodies ⬇️

artículo científico publicado el 31 de agosto de 2011

Characterization of a Bivalent Vaccine Capable of Inducing Protection Against Both Ebola and Cross-clade H5N1 Influenza in Mice

artículo científico publicado en 2015

Characterization of host immune responses in Ebola virus infections

artículo científico

Clinical Evaluation of Ebola Virus Disease Therapeutics

artículo científico publicado en 2017

Complete protection of the BALB/c and C57BL/6J mice against Ebola and Marburg virus lethal challenges by pan-filovirus T-cell epigraph vaccine

artículo científico publicado en 2019

Comprehensive functional analysis of N-linked glycans on Ebola virus GP1.

artículo científico publicado en 2014

Computer-Aided Discovery and Characterization of Novel Ebola Virus Inhibitors.

artículo científico publicado en 2018

Cooperativity Enables Non-neutralizing Antibodies to Neutralize Ebolavirus

artículo científico publicado en 2017

Correction to: Impact of intensive care unit supportive care on the physiology of Ebola virus disease in a universally lethal non-human primate model

scientific article published on 04 December 2019

Deep-sequencing of Marburg virus genome during sequential mouse passaging and cell-culture adaptation reveals extensive changes over time

artículo científico publicado en 2017

Delivering Prolonged Intensive Care to a Non-human Primate: A High Fidelity Animal Model of Critical Illness

artículo científico publicado en 2017

Designing Efficacious Vesicular Stomatitis Virus-Vectored Vaccines Against Ebola Virus

artículo científico publicado en 2016

Development and Characterization of a Guinea Pig-Adapted Sudan Virus

artículo científico publicado en 2015

Development of a Human Antibody Cocktail that Deploys Multiple Functions to Confer Pan-Ebolavirus Protection

scientific article published in 2019

Development of an antigen detection assay for early point-of-care diagnosis of Zaire ebolavirus

artículo científico publicado en 2020

Development of experimental and early investigational drugs for the treatment of Ebola virus infections

artículo científico

Diagnostic strategies for Ebola virus detection

artículo científico publicado en 2016

Ebola GP-specific monoclonal antibodies protect mice and guinea pigs from lethal Ebola virus infection

artículo científico publicado en 2012

Ebola viral load at diagnosis associates with patient outcome and outbreak evolution

artículo científico publicado en 2015

Ebola virus infection kinetics in chimeric mice reveal a key role of T cells as barriers for virus dissemination

scientific article published on 03 March 2017

Ebola virus transmission in guinea pigs

artículo científico publicado en 2014

Emetine inhibits Zika and Ebola virus infections through two molecular mechanisms: inhibiting viral replication and decreasing viral entry

artículo científico publicado en 2018

Equine immunoglobulin F(ab') fragments protect mice from Rift Valley fever virus infection

artículo científico publicado en 2018

Equine-Origin Immunoglobulin Fragments Protect Nonhuman Primates from Ebola Virus Disease

Establishment and characterization of a lethal mouse model for the Angola strain of Marburg virus

artículo científico publicado en 2014

Evaluation of transmission risks associated with in vivo replication of several high containment pathogens in a biosafety level 4 laboratory

artículo científico publicado en 2014

Ferrets Infected with Bundibugyo Virus or Ebola Virus Recapitulate Important Aspects of Human Filovirus Disease

scientific article published on 03 August 2016

From bench to almost bedside: the long road to a licensed Ebola virus vaccine

artículo científico publicado en 2017

Funding vaccines for emerging infectious diseases

artículo científico publicado en 2017

Gene Transfer of ZMapp Antibodies Mediated By Recombinant Adeno-Associated Virus Protects Against Ebola Infections

artículo científico publicado en 2017

Generation and Characterization of Anti-Filovirus Nucleoprotein Monoclonal Antibodies

scholarly article by Md Niaz Rahim et al published 14 March 2019 in Viruses

Identification of a clinical compound losmapimod that blocks Lassa virus entry

scientific article published on 04 April 2019

Immune Response to Marburg Virus Angola Infection in Nonhuman Primates

artículo científico publicado en 2015

Immune parameters correlate with protection against ebola virus infection in rodents and nonhuman primates

artículo científico publicado en 2012

Immunization with vesicular stomatitis virus vaccine expressing the Ebola glycoprotein provides sustained long-term protection in rodents

artículo científico publicado en 2014

Immunization-Elicited Broadly Protective Antibody Reveals Ebolavirus Fusion Loop as a Site of Vulnerability.

artículo científico publicado en 2017

Impact of intensive care unit supportive care on the physiology of Ebola virus disease in a universally lethal non-human primate model

artículo científico publicado en 2019

In Vivo Delivery of Synthetic Human DNA-Encoded Monoclonal Antibodies Protect against Ebolavirus Infection in a Mouse Model

scientific article published on 01 November 2018

Inactivation of Zaire ebolavirus Variant Makona in Human Serum Samples Analyzed by Enzyme-Linked Immunosorbent Assay

artículo científico publicado en 2016

Incorporation of Ebola glycoprotein into HIV particles facilitates dendritic cell and macrophage targeting and enhances HIV-specific immune responses

article

Intra-host Ebola viral adaption during human infection

artículo científico publicado en 2019

Intramuscular Adeno-Associated Virus-Mediated Expression of Monoclonal Antibodies Provides 100% Protection Against Ebola Virus Infection in Mice

artículo científico publicado en 2018

Intranasal immunization with an adenovirus vaccine protects guinea pigs from Ebola virus transmission by infected animals

artículo científico publicado en 2015

Marburg and Ravn Virus Infections Do Not Cause Observable Disease in Ferrets

scholarly article by Gary Wong et al published 22 November 2018 in Journal of Infectious Diseases

Modeling Ebola Virus Transmission Using Ferrets

article

Modelling the effect of early detection of Ebola

artículo científico publicado en 2015

Molecular characterization of the monoclonal antibodies composing ZMAb: a protective cocktail against Ebola virus

artículo científico publicado en 2014

Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus

artículo científico publicado en 2016

Monoclonal antibodies combined with adenovirus-vectored interferon significantly extend the treatment window in Ebola virus-infected guinea pigs

artículo científico publicado en 2013

More Challenges From Ebola: Infection of the Central Nervous System

artículo científico publicado en 2016

Mucosal immunization of cynomolgus macaques with the VSVDeltaG/ZEBOVGP vaccine stimulates strong ebola GP-specific immune responses

artículo científico publicado en 2009

Nanozyme-strip for rapid local diagnosis of Ebola

artículo científico publicado en 2015

Naturally-occurring single mutations in Ebola observably impact infectivity

scholarly article by Gary Wong et al published 17 October 2018 in Journal of Virology

Noncovalent SUMO-interaction motifs in HIV integrase play important roles in SUMOylation, cofactor binding, and virus replication

article

Optimization of Prime-Boost Vaccination Strategies Against Mouse-Adapted Ebolavirus in a Short-Term Protection Study

artículo científico publicado en 2015

Pathogenicity Comparison Between the Kikwit and Makona Ebola Virus Variants in Rhesus Macaques

artículo científico publicado en 2016

Peste des Petits Ruminants Virus-Like Particles Induce a Potent Humoral and Cellular Immune Response in Goats

artículo científico publicado en 2019

Post-exposure immunotherapy for two ebolaviruses and Marburg virus in nonhuman primates

scientific article published in Nature Communications

Post-exposure therapy of filovirus infections

artículo científico publicado en 2014

Postexposure Protective Efficacy of T-705 (Favipiravir) Against Sudan Virus Infection in Guinea Pigs

scholarly article by Md N Rahim et al published 22 November 2018 in Journal of Infectious Diseases

Potent neutralizing monoclonal antibodies against Ebola virus infection

artículo científico publicado en 2016

Potent neutralizing monoclonal antibodies against Ebola virus isolated from vaccinated donors

artículo científico publicado en 2020

Production and characterization of monoclonal antibodies against different epitopes of Ebola virus antigens.

artículo científico publicado en 2007

Progression of Ebola Therapeutics During the 2014-2015 Outbreak

artículo científico publicado en 2016

Prophylactic Efficacy of Quercetin 3-β-O-d-Glucoside against Ebola Virus Infection

artículo científico publicado en 2016

Protective Efficacy and Long-Term Immunogenicity in Cynomolgus Macaques by Ebola Virus Glycoprotein Synthetic DNA Vaccines

artículo científico publicado en 2019

Purification and characterization of monoclonal IgG antibodies recognizing Ebola virus glycoprotein

artículo científico publicado en 2018

Retrospective studies: excellent tools to complement surveillance

artículo científico publicado en 2013

Reversion of advanced Ebola virus disease in nonhuman primates with ZMapp

artículo científico publicado en 2014

Small Animal Models for Evaluating Filovirus Countermeasures

artículo científico publicado en 2018

Spread of ZIKV and YFV to China: Potential Implications

artículo científico publicado en 2016

Structures of protective antibodies reveal sites of vulnerability on Ebola virus

artículo científico publicado en 2014

Successful treatment of Marburg virus with orally administrated T-705 (Favipiravir) in a mouse model

artículo científico publicado en 2018

Successful treatment of ebola virus-infected cynomolgus macaques with monoclonal antibodies

artículo científico publicado en 2012

Sustained protection against Ebola virus infection following treatment of infected nonhuman primates with ZMAb

artículo científico publicado en 2013

Synergistic drug combination effectively blocks Ebola virus infection

artículo científico publicado en 2016

Systematic Analysis of Monoclonal Antibodies against Ebola Virus GP Defines Features that Contribute to Protection

Tangeretin, an extract from Citrus peels, blocks cellular entry of arenaviruses that cause viral hemorrhagic fever

scientific article published on 16 October 2018

Testing Experimental Therapies in a Guinea Pig Model for Hemorrhagic Fever

artículo científico publicado en 2018

The Cytokine Response Profile of Ebola Virus Disease in a Large Cohort of Rhesus Macaques Treated With Monoclonal Antibodies

The Makona Variant of Ebola Virus Is Highly Lethal to Immunocompromised Mice and Immunocompetent Ferrets

scholarly article by Gary Wong et al published 22 November 2018 in Journal of Infectious Diseases

The Roles of Ebola Virus Soluble Glycoprotein in Replication, Pathogenesis, and Countermeasure Development

scientific article published on 31 October 2019

The Tetherin Antagonism of the Ebola Virus Glycoprotein Requires an Intact Receptor-Binding Domain and Can Be Blocked by GP1-Specific Antibodies

artículo científico publicado en 2016

The emergence of antibody therapies for Ebola

artículo científico publicado en 2015

The multiple roles of sGP in Ebola pathogenesis

artículo científico publicado en 2015

Treatment with hyperimmune equine immunoglobulin or immunoglobulin fragments completely protects rodents from Ebola virus infection

artículo científico publicado en 2016

Two-mAb cocktail protects macaques against the Makona variant of Ebola virus

artículo científico publicado en 2016

Ultrasensitive Ebola Virus Detection Based on Electroluminescent Nanospheres and Immunomagnetic Separation

artículo científico publicado en 2017

VSVΔG/EBOV GP-induced innate protection enhances natural killer cell activity to increase survival in a lethal mouse adapted Ebola virus infection

artículo científico publicado en 2015

Virus inoculation and treatment regimens for evaluating anti-filovirus monoclonal antibody efficacy in vivo

artículo científico publicado en 2019

mAbs and Ad-vectored IFN-α therapy rescue Ebola-infected nonhuman primates when administered after the detection of viremia and symptoms

artículo científico publicado en 2013

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