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"Direct to Drug" screening as a precision medicine tool in multiple myeloma

scientific article published on 11 May 2020

(A)symmetric stem cell replication and cancer

artículo científico publicado en 2007

A Modern Primer on Light Chain Amyloidosis in 592 Patients With Mass Spectrometry-Verified Typing

scientific article published on 13 February 2019

A Patient With Hereditary ATTR and a Novel AGel p.Ala578Pro Amyloidosis

artículo científico publicado en 2018

A Phase II study of (153)Sm-EDTMP and high-dose melphalan as a peripheral blood stem cell conditioning regimen in patients with multiple myeloma

scientific article published on June 2010

A comparison of lenalidomide/dexamethasone versus cyclophosphamide/lenalidomide/dexamethasone versus cyclophosphamide/bortezomib/dexamethasone in newly diagnosed multiple myeloma

artículo científico publicado en 2011

A critical review of anagrelide therapy in essential thrombocythemia and related disorders

artículo científico publicado en 2005

A detailed evaluation of the current renal response criteria in AL amyloidosis: is it time for a revision?

artículo científico publicado en 2013

A deterministic model for the occurrence and dynamics of multiple mutations in hierarchically organized tissues

artículo científico publicado en 2013

A microenvironment based model of antimitotic therapy of Gompertzian tumor growth.

artículo científico publicado en 2007

A phase 1 trial of 90Y-Zevalin radioimmunotherapy with autologous stem cell transplant for multiple myeloma

artículo científico publicado en 2017

A phase 2 study of lenalidomide, rituximab, cyclophosphamide, and dexamethasone (LR-CD) for untreated low-grade non-Hodgkin lymphoma requiring therapy

artículo científico publicado en 2017

A practical guide to defining high-risk myeloma for clinical trials, patient counseling and choice of therapy

artículo científico publicado en 2007

A promising approach for treatment of tumor-induced bone diseases: utilizing bisphosphonate derivatives of nucleoside antimetabolites

artículo científico publicado en 2010

A study from The Mayo Clinic evaluated long-term outcomes of kidney transplantation in patients with immunoglobulin light chain amyloidosis

artículo científico publicado en 2020

Abnormal FISH in patients with immunoglobulin light chain amyloidosis is a risk factor for cardiac involvement and for death.

artículo científico publicado en 2015

Acquired hematopoietic stem-cell disorders and mammalian size

artículo científico publicado en 2007

Activity of pomalidomide in patients with immunoglobulin light-chain amyloidosis

artículo científico publicado en 2012

Acute kidney injury during leukocyte engraftment after autologous stem cell transplantation in patients with light-chain amyloidosis

artículo científico publicado en 2011

Allometric scaling of the active hematopoietic stem cell pool across mammals

artículo científico publicado en 2006

An unusual cause of ascites

artículo científico publicado en 2015

Anagrelide: an update on its mechanisms of action and therapeutic potential

artículo científico publicado en 2004

Analysis of Clinical Factors and Outcomes Associated with Non-Utilization of Collected Peripheral Blood Stem Cells for Autologous Stem Cell Transplants in Transplant Eligible Patients with Multiple Myeloma.

artículo científico publicado en 2018

Angiomatoid fibrous histiocytoma in a 25-year-old male

artículo científico publicado en 2010

Asymptomatic immunoglobulin light chain amyloidosis (AL) at the time of diagnostic bone marrow biopsy in newly diagnosed patients with multiple myeloma and smoldering myeloma. A series of 144 cases and a review of the literature

artículo científico publicado en 2010

Autologous Stem Cell Transplant for IgM-Associated Amyloid Light-Chain Amyloidosis

scholarly article by M Hasib Sidiqi et al published March 2019 in Biology of Blood and Marrow Transplantation

Autologous Stem Cell Transplant for Immunoglobulin Light Chain Amyloidosis Patients Aged 70 to 75

artículo científico publicado en 2018

Autologous stem cell transplant for immunoglobulin light chain amyloidosis: a status report

artículo científico publicado en 2010

Autologous stem cell transplant for multiple myeloma patients 70 years or older

artículo científico publicado en 2016

Autologous stem cell transplant in 716 patients with multiple myeloma: low treatment-related mortality, feasibility of outpatient transplant, and effect of a multidisciplinary quality initiative

artículo científico publicado en 2008

Autologous stem cell transplantation for multiple myeloma patients aged ≥ 75 treated with novel agents

artículo científico publicado en 2020

Autologous stem cell transplantation in immunoglobulin light chain amyloidosis with factor X deficiency

artículo científico publicado en 2015

Autologous stem cell transplantation in patients of 70 years and older with multiple myeloma: Results from a matched pair analysis.

artículo científico publicado en 2008

Autologous stem cell transplantation in patients with AL amyloidosis with impaired renal function

scientific article published on 08 April 2019

Bendamustine and rituximab (BR) versus dexamethasone, rituximab, and cyclophosphamide (DRC) in patients with Waldenström macroglobulinemia

artículo científico publicado en 2018

Beta-blockers improve survival outcomes in patients with multiple myeloma: a retrospective evaluation

artículo científico publicado en 2016

Biomedical system dynamics to improve anemia control with darbepoetin alfa in long-term hemodialysis patients

scientific article published on 01 January 2014

Blood mass spectrometry detects residual disease better than standard techniques in light-chain amyloidosis

artículo científico publicado en 2020

Bone marrow plasma cells 20% or greater discriminate presentation, response, and survival in AL amyloidosis

scientific article published on 22 November 2019

Bortezomib, lenalidomide, and dexamethasone (VRd) followed by autologous stem cell transplant for multiple myeloma

scholarly article by M Hasib Sidiqi et al published 8 November 2018 in Blood Cancer Journal

Cancer biology: infectious tumour cells

artículo científico publicado en 2006

Cancer phenotype as the outcome of an evolutionary game between normal and malignant cells

artículo científico publicado en 2009

Changes in uninvolved immunoglobulins during induction therapy for newly diagnosed multiple myeloma

artículo científico publicado en 2017

Characteristics of exceptional responders to autologous stem cell transplantation in multiple myeloma

scientific article published on 28 August 2020

Characteristics of late transplant-associated thrombotic microangiopathy (TA-TMA) in patients who underwent allogeneic hematopoietic stem cell transplantation

artículo científico publicado en 2020

Characterization and prognostic implication of delayed complete response in AL amyloidosis

scientific article published on 23 November 2020

Circulating plasma cells detected by flow cytometry as a predictor of survival in 302 patients with newly diagnosed multiple myeloma

artículo científico publicado en 2005

Clinical Features and Treatment Outcomes of Patients With Necrobiotic Xanthogranuloma Associated With Monoclonal Gammopathies.

artículo científico publicado en 2016

Clinical and prognostic differences among patients with light chain deposition disease, myeloma cast nephropathy and both.

artículo científico publicado en 2015

Clinical characteristics and outcomes in biclonal gammopathies

artículo científico publicado en 2016

Clinical characteristics and treatment outcomes of newly diagnosed multiple myeloma with chromosome 1q abnormalities

artículo científico publicado en 2020

Clinical course and outcomes of patients with multiple myeloma who relapse after autologous stem cell therapy.

artículo científico publicado en 2016

Clinical outcome of immunoglobulin light chain amyloidosis affecting the kidney.

artículo científico publicado en 2009

Clinical presentation and outcomes in light chain amyloidosis patients with non-evaluable serum free light chains

artículo científico publicado en 2017

Clinical presentation and outcomes of patients with type 1 monoclonal cryoglobulinemia

artículo científico publicado en 2017

Clinical utility of the Revised International Staging System in unselected patients with newly diagnosed and relapsed multiple myeloma

scientific article published on 17 February 2017

Coexistent multiple myeloma or increased bone marrow plasma cells define equally high-risk populations in patients with immunoglobulin light chain amyloidosis

artículo científico publicado en 2013

Colon perforation in multiple myeloma patients - A complication of high-dose steroid treatment

scientific article published on 06 October 2020

Combination therapy with thalidomide and dexamethasone in patients with newly diagnosed multiple myeloma not undergoing upfront autologous stem cell transplantation: a phase II trial

artículo científico publicado en 2005

Combined I-124 positron emission tomography/computed tomography imaging of NIS gene expression in animal models of stably transfected and intravenously transfected tumor

artículo científico publicado en 2006

Comparable outcomes using propylene glycol-free melphalan for autologous stem cell transplantation in multiple myeloma.

artículo científico publicado en 2018

Comparative analysis of staging systems in AL amyloidosis

scientific article published on 23 January 2019

Comparison of different techniques to identify cardiac involvement in immunoglobulin light chain (AL) amyloidosis

Comparison of high-dose CY and growth factor with growth factor alone for mobilization of stem cells for transplantation in patients with multiple myeloma

artículo científico publicado en 2008

Compartmental architecture and dynamics of hematopoiesis

artículo científico publicado en 2007

Concomitant neutrophil JAK2 mutation screening and PRV-1 expression analysis in myeloproliferative disorders and secondary polycythaemia

artículo científico publicado en 2005

Conflicts of interest, authorship, and disclosures in industry-related scientific publications

artículo científico publicado en 2010

Continued improvement in survival in multiple myeloma: changes in early mortality and outcomes in older patients.

artículo científico publicado en 2013

Correction: (A)Symmetric Stem Cell Replication and Cancer.

artículo científico publicado en 2007

Correction: Bone marrow plasma cells 20% or greater discriminate presentation, response, and survival in AL amyloidosis

artículo científico publicado en 2020

Correlation between urine ACR and 24-h proteinuria in a real-world cohort of systemic AL amyloidosis patients

artículo científico publicado en 2020

Cost-effectiveness analysis of a risk-adapted algorithm of plerixafor use for autologous peripheral blood stem cell mobilization

artículo científico publicado en 2012

Cyclic neutropenia in mammals

artículo científico publicado en 2008

Cyclophosphamide Mobilization Does Not Improve Outcome in Patients Receiving Stem Cell Transplantation for Multiple Myeloma

artículo científico publicado en 2006

Cytogenetic Features and Clinical Outcomes of Patients With Non-secretory Multiple Myeloma in the Era of Novel Agent Induction Therapy

artículo científico publicado en 2019

Cytogenetic abnormalities in multiple myeloma: association with disease characteristics and treatment response

artículo científico publicado en 2020

Daratumumab-based therapy in patients with heavily-pretreated AL amyloidosis

artículo científico publicado en 2018

Death by fusion for acute leukemia cells

scientific article published on 06 March 2010

Defining cure in multiple myeloma: a comparative study of outcomes of young individuals with myeloma and curable hematologic malignancies.

artículo científico publicado en 2018

Delayed neutrophil engraftment in patients receiving Daratumumab as part of their first induction regimen for multiple myeloma

scientific article published on 21 October 2019

Delineation of the timing of second line therapy post- autologous stem cell transplant in patients with AL amyloidosis

artículo científico

Depth of organ response in AL amyloidosis is associated with improved survival: grading the organ response criteria.

artículo científico publicado en 2018

Depth of organ response in AL amyloidosis is associated with improved survival: new proposed organ response criteria

scientific article published on 01 January 2019

Depth of response prior to autologous stem cell transplantation predicts survival in light chain amyloidosis

artículo científico publicado en 2020

Der(6)t(1;6)(q21-23;p21.3): a specific cytogenetic abnormality in myelofibrosis with myeloid metaplasia.

artículo científico publicado en 2005

Detecting truly clonal alterations from multi-region profiling of tumours

artículo científico publicado en 2017

Dexamethasone, rituximab and cyclophosphamide for relapsed and/or refractory and treatment-naïve patients with Waldenstrom macroglobulinemia

artículo científico

Diagnosis and Management of Waldenström Macroglobulinemia: Mayo Stratification of Macroglobulinemia and Risk-Adapted Therapy (mSMART) Guidelines 2016.

artículo científico publicado en 2017

Diagnosis and management of Waldenström macroglobulinemia: Mayo stratification of macroglobulinemia and risk-adapted therapy (mSMART) guidelines

artículo científico publicado en 2010

Differences in engraftment with day-1 compared with day-2 melphalan prior to stem cell infusion in myeloma patients receiving autologous stem cell transplant

artículo científico publicado en 2020

Digoxin use in systemic light-chain (AL) amyloidosis: contra-indicated or cautious use?

article by Eli Muchtar et al published 12 March 2018 in Amyloid

Discordance between serum cardiac biomarker and immunoglobulin-free light-chain response in patients with immunoglobulin light-chain amyloidosis treated with immune modulatory drugs

artículo científico publicado en 2010

Dynamic iodide trapping by tumor cells expressing the thyroidal sodium iodide symporter

artículo científico publicado en 2004

Dynamics of haemopoiesis across mammals.

artículo científico publicado en 2008

Dynamics of leukemia stem-like cell extinction in acute promyelocytic leukemia

artículo científico publicado en 2014

Dynamics of melanoma tumor therapy with vesicular stomatitis virus: explaining the variability in outcomes using mathematical modeling.

artículo científico publicado en 2011

Dynamics of multiple myeloma tumor therapy with a recombinant measles virus

artículo científico publicado en 2009

Dynamics of mutant cells in hierarchical organized tissues

artículo científico publicado en 2011

Early relapse following initial therapy for multiple myeloma predicts poor outcomes in the era of novel agents

artículo científico publicado en 2016

Early versus delayed autologous transplantation after immunomodulatory agents-based induction therapy in patients with newly diagnosed multiple myeloma.

artículo científico publicado en 2011

Efficacy of VDT PACE-like regimens in treatment of relapsed/refractory multiple myeloma

artículo científico publicado en 2017

Efficacy of daratumumab-based therapies in patients with relapsed, refractory multiple myeloma treated outside of clinical trials

artículo científico publicado en 2017

Efficacy of retreatment with immunomodulatory drugs (IMiDs) in patients receiving IMiDs for initial therapy of newly diagnosed multiple myeloma

artículo científico publicado en 2011

Efficacy of thalidomide- or lenalidomide-based therapy in proliferative multiple myeloma

artículo científico publicado en 2011

Elevated pre-transplant C-reactive protein identifies a high-risk subgroup in multiple myeloma patients undergoing delayed autologous stem cell transplantation

artículo científico publicado en 2017

Elevation of serum lactate dehydrogenase in AL amyloidosis reflects tissue damage and is an adverse prognostic marker in patients not eligible for stem cell transplantation

artículo científico publicado en 2017

Emerging therapies for multiple myeloma

artículo científico publicado en 2009

Enhancing the R-ISS classification of newly diagnosed multiple myeloma by quantifying circulating clonal plasma cells

artículo científico publicado en 2020

Erratum: Long-term outcome of patients with multiple myeloma-related advanced renal failure following auto-SCT

scholarly article published in Bone Marrow Transplantation

Erratum: Melphalan and prednisone versus melphalan, prednisone and thalidomide for elderly and/or transplant-ineligible patients with multiple myeloma: a meta-analysis

scholarly article published in Leukemia

Estimation of Oncolytic Virus Populations within Tumors

Evaluation of pretransplant factors predicting cardiac dysfunction following high-dose melphalan conditioning and autologous peripheral blood stem cell transplantation

scientific article published on 13 July 2012

Evolutionary dynamics of chronic myeloid leukemia

artículo científico publicado en 2010

Evolutionary dynamics of paroxysmal nocturnal hemoglobinuria.

artículo científico publicado en 2018

Evolutionary dynamics of two related malignant plasma cell lines ⬇️

artículo científico publicado el 15 de septiembre de 2010

Evolving changes in disease biomarkers and risk of early progression in smoldering multiple myeloma

artículo científico publicado en 2016

Explaining the in vitro and in vivo differences in leukemia therapy.

artículo científico publicado en 2011

Factors associated with favorable outcome after allogeneic hematopoietic stem cell transplantation for multiple myeloma.

artículo científico publicado en 2009

Fifteen year overall survival rates after autologous stem cell transplantation for AL amyloidosis

scientific article published on 11 July 2019

Flow cytometric detection of circulating myeloma cells before transplantation in patients with multiple myeloma: a simple risk stratification system

artículo científico publicado en 2005

Focal and segmental glomerulosclerosis and plasma cell proliferative disorders

artículo científico publicado en 2005

Genetic progression and the waiting time to cancer

artículo científico publicado en 2007

Genetically targeted radiotherapy for multiple myeloma

artículo científico publicado en 2003

HIV-1 Activation of Innate Immunity Depends Strongly on the Intracellular Level of TREX1 and Sensing of Incomplete Reverse Transcription Products

article

Hematologic characteristics of proliferative glomerulonephritides with nonorganized monoclonal immunoglobulin deposits

artículo científico

Hematology patient reported symptom screen to assess quality of life for AL amyloidosis

artículo científico publicado en 2017

Hematopoietic recovery kinetics predicts for poor CD34+ cell mobilization after cyclophosphamide chemotherapy in multiple myeloma

scientific article published on 29 September 2011

Hematopoietic score predicts outcomes in newly diagnosed multiple myeloma patients

scientific article published on 29 October 2019

High sensitivity cardiac troponin T in patients with immunoglobulin light chain amyloidosis

scientific article published on 08 January 2014

High-dose melphalan and peripheral blood stem cell transplantation for light-chain amyloidosis with cardiac involvement

artículo científico publicado en 2011

How best to use new therapies in multiple myeloma

scientific article published on April 2010

How many samples are needed to infer truly clonal mutations from heterogenous tumours?

scientific article published on 29 April 2019

How we manage autologous stem cell transplantation for patients with multiple myeloma

artículo científico publicado en 2014

Hydroxyurea: The drug of choice for polycythemia vera and essential thrombocythemia

artículo científico publicado en 2006

IAP antagonists induce anti-tumor immunity in multiple myeloma.

artículo científico publicado en 2016

IDH mutations and trisomy 8 in myelodysplastic syndromes and acute myeloid leukemia ⬇️

artículo científico publicado el 23 de septiembre de 2010

Ibrutinib monotherapy outside of clinical trial setting in Waldenström macroglobulinaemia: practice patterns, toxicities and outcomes

scientific article published on 29 August 2019

Idiotype-pulsed antigen-presenting cells following autologous transplantation for multiple myeloma may be associated with prolonged survival

artículo científico publicado en 2009

Image-guided radiovirotherapy for multiple myeloma using a recombinant measles virus expressing the thyroidal sodium iodide symporter ⬇️

artículo científico publicado el 6 de noviembre de 2003

Imaging findings in 22 cases of Schnitzler syndrome: characteristic para-articular osteosclerosis, and the "hot knees" sign differential diagnosis

artículo científico publicado en 2014

Imatinib and type 2 diabetes

scientific article published on 01 March 2007

Immunoglobulin D amyloidosis: a distinct entity

artículo científico publicado en 2011

Immunoglobulin free light chains and solitary plasmacytoma of bone

artículo científico publicado en 2006

Immunoglobulin light chain amyloidosis is diagnosed late in patients with preexisting plasma cell dyscrasias

scientific article published on 02 September 2014

Immunoparesis in newly diagnosed AL amyloidosis is a marker for response and survival

artículo científico publicado en 2016

Immunoparesis in newly diagnosed AL amyloidosis is a marker for response and survival

Immunoparesis status in AL amyloidosis at diagnosis affects response and survival by regimen type

Immunoparesis status in immunoglobulin light chain amyloidosis at diagnosis affects response and survival by regimen type

artículo científico publicado en 2016

Impact of MYD88L265P mutation status on histological transformation of Waldenström Macroglobulinemia

scientific article published on 31 December 2019

Impact of Post-Transplant Response and Minimal Residual Disease on Survival in Myeloma with High-Risk Cytogenetics.

artículo científico publicado en 2017

Impact of acquired del(17p) in multiple myeloma

artículo científico publicado en 2019

Impact of additional cytoreduction following autologous SCT in multiple myeloma.

scientific article published on 16 June 2008

Impact of consolidation therapy post autologous stem cell transplant in patients with light chain amyloidosis

scientific article published on 23 July 2019

Impact of cytogenetic classification on outcomes following early high-dose therapy in multiple myeloma

artículo científico publicado en 2015

Impact of dexamethasone responsiveness on long term outcome in patients with newly diagnosed multiple myeloma

artículo científico publicado en 2009

Impact of duration of induction therapy on survival in newly diagnosed multiple myeloma patients undergoing upfront autologous stem cell transplantation.

artículo científico publicado en 2018

Impact of early relapse after auto-SCT for multiple myeloma.

artículo científico publicado en 2008

Impact of involved free light chain (FLC) levels in patients achieving normal FLC ratio after initial therapy in light chain amyloidosis (AL).

artículo científico publicado en 2017

Impact of pre-transplant bone marrow plasma cell percentage on post-transplant response and survival in newly diagnosed multiple myeloma.

artículo científico publicado en 2016

Impact of pretransplant therapy in patients with newly diagnosed myeloma undergoing autologous SCT.

artículo científico publicado en 2008

Impact of prior melphalan exposure on stem cell collection in light chain amyloidosis

artículo científico publicado en 2017

Impact of risk stratification on outcome among patients with multiple myeloma receiving initial therapy with lenalidomide and dexamethasone

artículo científico publicado en 2009

Implications and outcomes of MRD-negative multiple myeloma patients with immunofixation positivity

scientific article published on 30 December 2019

Implications of MYC Rearrangements in Newly Diagnosed Multiple Myeloma

artículo científico publicado en 2020

Implications of continued response after autologous stem cell transplantation for multiple myeloma

artículo científico publicado en 2013

Implications of detecting serum monoclonal protein by MASS-fix following stem cell transplantation in multiple myeloma

artículo científico publicado en 2020

Importance of achieving stringent complete response after autologous stem-cell transplantation in multiple myeloma

artículo científico publicado en 2013

Improved outcomes for newly diagnosed AL amyloidosis between 2000 and 2014: cracking the glass ceiling of early death

artículo científico publicado en 2017

Improved survival in multiple myeloma and the impact of novel therapies

artículo científico publicado en 2007

Improvement in renal function and its impact on survival in patients with newly diagnosed multiple myeloma

artículo científico publicado en 2015

In silico evolutionary dynamics of tumour virotherapy

artículo científico publicado en 2009

In vitro and in silico multidimensional modeling of oncolytic tumor virotherapy dynamics

artículo científico publicado en 2019

In vivo and in silico studies on single versus multiple transplants for multiple myeloma.

artículo científico publicado en 2007

In vivo imaging and tumor therapy with the sodium iodide symporter

artículo científico publicado en 2003

Incidence of supraventricular arrhythmias during autologous peripheral blood stem cell transplantation

artículo científico publicado en 2013

Increased Bone Marrow Plasma-Cell Percentage Predicts Outcomes in Newly Diagnosed Multiple Myeloma Patients

scientific article published on 07 April 2020

Independent Prognostic Value of Stroke Volume Index in Patients With Immunoglobulin Light Chain Amyloidosis

artículo científico publicado en 2018

Induction therapy pre-autologous stem cell transplantation in immunoglobulin light chain amyloidosis: a retrospective evaluation

artículo científico publicado en 2016

Integrated safety profile of selinexor in multiple myeloma: experience from 437 patients enrolled in clinical trials

artículo científico publicado en 2020

Interaction of measles virus vectors with Auger electron emitting radioisotopes

artículo científico publicado en 2005

Interphase fluorescence in situ hybridization in untreated AL amyloidosis has an independent prognostic impact by abnormality type and treatment category

artículo científico publicado en 2016

Intestinal lymphangiectasia with protein-losing enteropathy in Waldenstrom macroglobulinemia

artículo científico publicado en 2007

In Vivo Imaging of Oncolytic Measles Virus Propagation with Single-Cell Resolution.

artículo científico publicado en 2018

Kidney Involvement of Patients with Waldenström Macroglobulinemia and Other IgM-Producing B Cell Lymphoproliferative Disorders

scientific article published on 30 May 2018

Kinetics of organ response and survival following normalization of the serum free light chain ratio in AL amyloidosis

artículo científico publicado en 2015

Lenalidomide plus dexamethasone versus thalidomide plus dexamethasone in newly diagnosed multiple myeloma: a comparative analysis of 411 patients

artículo científico publicado en 2009

Lenalidomide, cyclophosphamide and dexamethasone (CRd) for newly diagnosed multiple myeloma: results from a phase 2 trial

artículo científico publicado en 2011

Lenalidomide, cyclophosphamide, and dexamethasone (CRd) for light-chain amyloidosis: long-term results from a phase 2 trial

artículo científico publicado en 2012

Light chain type predicts organ involvement and survival in AL amyloidosis patients receiving stem cell transplantation

artículo científico publicado en 2018

Long-term disease control in patients with newly diagnosed multiple myeloma after suspension of lenalidomide therapy

artículo científico publicado en 2014

Long-term outcome of patients with POEMS syndrome: An update of the Mayo Clinic experience

artículo científico publicado en 2016

Long-term outcome of patients with mutiple myeloma-related advanced renal failure following auto-SCT

artículo científico publicado en 2013

Long-term outcome with lenalidomide and dexamethasone therapy for newly diagnosed multiple myeloma.

artículo científico publicado en 2013

Long-term outcomes after autologous stem cell transplantation for patients with POEMS syndrome (osteosclerotic myeloma): a single-center experience

artículo científico publicado en 2012

Long-term outcomes of IMiD-based trials in patients with immunoglobulin light-chain amyloidosis: a pooled analysis

artículo científico publicado en 2020

Long-term outcomes of patients with light chain amyloidosis (AL) after renal transplantation with or without stem cell transplantation

artículo científico publicado en 2011

Low levels of interleukin-1 receptor antagonist (IL-1RA) predict engraftment syndrome after autologous stem cell transplantation in POEMS syndrome and other plasma cell neoplasms.

artículo científico publicado en 2013

Low risk of symptomatic venous thromboembolic events during growth factor administration for PBSC mobilization

artículo científico publicado en 2010

MYD88 mutation status does not impact overall survival in Waldenström macroglobulinemia.

artículo científico publicado en 2017

Majority of patients receiving initial therapy with lenalidomide-based regimens can be successfully mobilized with appropriate mobilization strategies

artículo científico publicado en 2011

Management of newly diagnosed symptomatic multiple myeloma: updated Mayo Stratification of Myeloma and Risk-Adapted Therapy (mSMART) consensus guidelines

scientific article published on December 2009

Management of newly diagnosed symptomatic multiple myeloma: updated Mayo Stratification of Myeloma and Risk-Adapted Therapy (mSMART) consensus guidelines 2013.

artículo científico

Mathematical modeling of cancer radiovirotherapy

artículo científico publicado en 2005

Mayo clinic consensus statement for the use of bisphosphonates in multiple myeloma

artículo científico publicado en 2006

Melphalan and prednisone versus melphalan, prednisone and thalidomide for elderly and/or transplant ineligible patients with multiple myeloma: a meta-analysis

artículo científico publicado en 2011

Metformin inhibits IL-6 signaling by decreasing IL-6R expression on multiple myeloma cells

scientific article published on 15 April 2019

Microcytosis in agnogenic myeloid metaplasia: prevalence and clinical correlates.

artículo científico publicado en 2005

Modeling of cancer virotherapy with recombinant measles viruses

artículo científico publicado en 2008

Modeling the architecture and dynamics of hematopoiesis ⬇️

artículo científico publicado el 1 de marzo de 2010

Monitoring the initial delivery of an oncolytic measles virus encoding the human sodium iodide symporter to solid tumors using contrast-enhanced computed tomography

artículo científico publicado en 2012

Monoclonal gammopathy plus positive amyloid biopsy does not always equal AL amyloidosis

artículo científico publicado en 2019

Mouse models and the RANKL/OPG axis in myeloma bone disease

artículo científico publicado en 2007

Multicentric Castleman disease – a single center experience of treatment with a focus on autologous stem cell transplantation

Multiple mutant clones in blood rarely coexist.

artículo científico publicado en 2008

Mutations in the stalk region of the measles virus hemagglutinin inhibit syncytium formation but not virus entry

artículo científico publicado en 2010

Myelofibrosis with myeloid metaplasia: new developments in pathogenesis and treatment

artículo científico publicado en 2004

Myelomatous Involvement of the Central Nervous System

artículo científico publicado en 2016

N-terminal fragment of the type-B natriuretic peptide (NT-proBNP) contributes to a simple new frailty score in patients with newly diagnosed multiple myeloma

artículo científico publicado en 2016

Natural history of multiple myeloma with de novo del(17p)

scholarly article by Arjun Lakshman et al published 7 March 2019 in Blood Cancer Journal

Natural history of t(11;14) multiple myeloma

artículo científico publicado en 2017

Neutral evolution in paroxysmal nocturnal hemoglobinuria

artículo científico publicado en 2008

On the dynamics of neutral mutations in a mathematical model for a homogeneous stem cell population

artículo científico publicado en 2012

On the origin of multiple mutant clones in paroxysmal nocturnal hemoglobinuria

artículo científico publicado en 2007

Oncolytic Measles Virotherapy and Opposition to Measles Vaccination

scientific article published on 22 June 2019

Oncolytic measles viruses encoding interferon beta and the thyroidal sodium iodide symporter gene for mesothelioma virotherapy

artículo científico publicado en 2010

Oncolytic virotherapy – in vivo veritas

scientific article published on 20 November 2018

Ontogenic growth as the root of fundamental differences between childhood and adult cancer

artículo científico publicado en 2015

Ontogenic growth of the haemopoietic stem cell pool in humans

artículo científico publicado en 2007

Optimization of virotherapy for cancer.

artículo científico publicado en 2009

Optimized Treatment Schedules for Chronic Myeloid Leukemia ⬇️

artículo científico publicado en 2016

Optimizing deep response assessment for AL amyloidosis using involved free light chain level at end of therapy: failure of the serum free light chain ratio

scientific article published on 26 September 2018

Oral Selinexor-Dexamethasone for Triple-Class Refractory Multiple Myeloma

artículo científico publicado en 2019

Outcome after autologous stem cell transplantation for multiple myeloma in patients with preceding plasma cell disorders.

artículo científico publicado en 2008

Outcome of very young (≤40 years) patients with immunoglobulin light chain (AL) amyloidosis

Outcomes and treatments of patients with immunoglobulin light chain amyloidosis who progress or relapse postautologous stem cell transplant.

artículo científico publicado en 2014

Outcomes of Multiple Myeloma Patients with Del 17p Undergoing Autologous Stem Cell Transplantation

artículo científico publicado en 2020

Outcomes of Patients with Light Chain Amyloidosis Who Had Autologous Stem Cell Transplantation with 3 or More Organs Involved

artículo científico publicado en 2019

Outcomes of maintenance therapy with lenalidomide or bortezomib in multiple myeloma in the setting of early autologous stem cell transplantation

artículo científico

Outcomes of patients with POEMS syndrome treated initially with radiation

artículo científico publicado en 2013

Outcomes of patients with renal monoclonal immunoglobulin deposition disease

artículo científico publicado en 2016

Outcomes of primary refractory multiple myeloma and the impact of novel therapies

artículo científico publicado en 2015

Outcomes with different administration schedules of Bortezomib in Bortezomib, Lenalidomide and dexamethasone (VRd) as first-line therapy in Multiple Myeloma

scientific article published on 16 December 2020

Outcomes with early response to first-line treatment in patients with newly diagnosed multiple myeloma

artículo científico publicado en 2019

Outcomes with early vs. deferred stem cell transplantation in light chain amyloidosis

artículo científico publicado en 2020

Overall survival of transplant eligible patients with newly diagnosed multiple myeloma: comparative effectiveness analysis of modern induction regimens on outcome

scholarly article by Ashley R Paquin et al published 11 December 2018 in Blood Cancer Journal

Overuse of organ biopsies in immunoglobulin light chain amyloidosis (AL): the consequence of failure of early recognition

artículo científico publicado en 2017

Patients with immunoglobulin light chain amyloidosis undergoing autologous stem cell transplantation have superior outcomes compared with patients with multiple myeloma: a retrospective review from a tertiary referral center

artículo científico publicado en 2013

Peripheral blood stem cell transplant for POEMS syndrome is associated with high rates of engraftment syndrome

artículo científico publicado en 2008

Phase 1/2 trial of ixazomib, cyclophosphamide and dexamethasone in patients with previously untreated symptomatic multiple myeloma

scientific article published on 30 July 2018

Phase 2 trial of intravenously administered plerixafor for stem cell mobilization in patients with multiple myeloma following lenalidomide-based initial therapy

artículo científico publicado en 2013

Phase I trial of systemic administration of Edmonston strain of measles virus genetically engineered to express the sodium iodide symporter in patients with recurrent or refractory multiple myeloma

artículo científico publicado en 2017

Pinhole micro-SPECT/CT for noninvasive monitoring and quantitation of oncolytic virus dispersion and percent infection in solid tumors

artículo científico publicado en 2011

Plasma cell proliferative index is an independent predictor of progression in smoldering multiple myeloma

article published in 2018

Plasma cell proliferative index post-transplant is a powerful predictor of prognosis in myeloma patients failing to achieve a complete response

artículo científico publicado en 2018

Plasma cell proliferative index predicts outcome in immunoglobulin light chain amyloidosis treated with stem cell transplantation.

artículo científico publicado en 2018

Plasma membrane phospholipid labeling to estimate tumor burden and kinetics

artículo científico publicado en 2008

Pomalidomide (CC4047) plus low dose dexamethasone (Pom/dex) is active and well tolerated in lenalidomide refractory multiple myeloma (MM).

artículo científico publicado en 2010

Pomalidomide (CC4047) plus low-dose dexamethasone as therapy for relapsed multiple myeloma

artículo científico publicado en 2009

Pomalidomide plus low-dose dexamethasone in myeloma refractory to both bortezomib and lenalidomide: comparison of 2 dosing strategies in dual-refractory disease

artículo científico publicado en 2011

Pomalidomide, Bortezomib and Dexamethasone (PVD) for Patients with Relapsed, Lenalidomide Refractory Multiple Myeloma

artículo científico publicado en 2017

Pomalidomide-dexamethasone in refractory multiple myeloma: Long-term follow-up of a multi-cohort phase II clinical trial

artículo científico

Positron emission tomography-computed tomography in the diagnostic evaluation of smoldering multiple myeloma: identification of patients needing therapy.

artículo científico publicado en 2015

Preclinical development of CD126 CAR-T cells with broad antitumor activity

artículo científico publicado en 2021

Preclinical pharmacology and toxicology of intravenous MV-NIS, an oncolytic measles virus administered with or without cyclophosphamide

artículo científico publicado en 2007

Predicting PBSC harvest failure using circulating CD34 levels: developing target-based cutoff points for early intervention.

artículo científico publicado en 2010

Predictors of early response to initial therapy in patients with newly diagnosed symptomatic multiple myeloma

artículo científico publicado en 2015

Predictors of early treatment failure following initial therapy for systemic immunoglobulin light-chain amyloidosis

artículo científico publicado en 2017

Predictors of short-term survival in Waldenström Macroglobulinemia

artículo científico publicado en 2020

Predictors of symptomatic hyperviscosity in Waldenström macroglobulinemia

scientific article published on 02 October 2018

Presence of unfavorable cytogenetic abnormalities is the strongest predictor of poor survival in secondary myelofibrosis

artículo científico publicado en 2006

Presentation and Outcomes of Localized Immunoglobulin Light Chain Amyloidosis: The Mayo Clinic Experience

artículo científico publicado en 2017

Prevalence and predictors of thyroid functional abnormalities in newly diagnosed AL amyloidosis

artículo científico publicado en 2017

Primary systemic amyloidosis in patients with Waldenström macroglobulinemia

artículo científico publicado en 2018

Progenitor cell self-renewal and cyclic neutropenia

artículo científico publicado en 2009

Prognosis in transplant-eligible patients with agnogenic myeloid metaplasia: a simple CBC-based scoring system

artículo científico publicado en 2006

Prognostic Role of Beta-2 Microglobulin in Patients with Light Chain Amyloidosis Treated with Autologous Stem Cell Transplantation

artículo científico publicado en 2020

Prognostic Significance of Holter Monitor Findings in Patients With Light Chain Amyloidosis

scientific article published on 02 February 2019

Prognostic Significance of Stringent Complete Response after Stem Cell Transplantation in Immunoglobulin Light Chain Amyloidosis

artículo científico publicado en 2018

Prognostic diversity among cytogenetic abnormalities in myelofibrosis with myeloid metaplasia.

artículo científico publicado en 2005

Prognostic restaging at the time of second-line therapy in patients with AL amyloidosis

artículo científico publicado en 2019

Prognostic significance of circulating plasma cells by multi-parametric flow cytometry in light chain amyloidosis.

artículo científico publicado en 2018

Prognostic significance of interphase FISH in monoclonal gammopathy of undetermined significance

scientific article published on 30 January 2018

Prognostic value of NT-ProBNP and troponin T in patients with light chain amyloidosis and kidney dysfunction undergoing autologous stem cell transplantation

artículo científico publicado en 2020

Prognostic value of minimal residual disease and polyclonal plasma cells in myeloma patients achieving a complete response to therapy

artículo científico publicado en 2019

Promising preclinical activity of 2-methoxyestradiol in multiple myeloma.

artículo científico publicado en 2002

Proteasome inhibitor associated thrombotic microangiopathy

artículo científico publicado en 2016

Pulmonary hypertension in patients with amyloidosis

artículo científico publicado en 2001

Pyoderma gangrenosum in hematologic malignancies: A systematic review

artículo científico publicado en 2019

Quantification of circulating clonal plasma cells via multiparametric flow cytometry identifies patients with smoldering multiple myeloma at high risk of progression

artículo científico publicado en 2016

Quantitative imaging and dynamics of tumor therapy with viruses

artículo científico publicado en 2021

Quantitative molecular imaging of viral therapy for pancreatic cancer using an engineered measles virus expressing the sodium-iodide symporter reporter gene

artículo científico publicado en 2009

Randomized phase 2 trial of ixazomib and dexamethasone in relapsed multiple myeloma not refractory to bortezomib

artículo científico publicado en 2016

Rapid assessment of hyperdiploidy in plasma cell disorders using a novel multi-parametric flow cytometry method

scientific article published on 08 January 2019

Recent improvements in survival in primary systemic amyloidosis and the importance of an early mortality risk score

artículo científico publicado en 2011

Reconstructing the in vivo dynamics of hematopoietic stem cells from telomere length distributions

artículo científico publicado en 2015

Refinement in patient selection to reduce treatment-related mortality from autologous stem cell transplantation in amyloidosis

artículo científico publicado en 2012

Refining amyloid complete hematological response: quantitative serum free light chains superior to ratio

artículo científico publicado en 2020

Relapse after complete response in newly diagnosed multiple myeloma: implications of duration of response and patterns of relapse

artículo científico publicado en 2018

Relationship Between Depth of Response and Outcome in Multiple Myeloma

scientific article published on 01 November 2007

Remission of disseminated cancer after systemic oncolytic virotherapy

artículo científico publicado en 2014

Replicative cellular age distributions in compartmentalized tissues

scholarly article by Marvin A Böttcher et al published August 2018 in Journal of the Royal Society Interface

Reply: Evolutionary game theory: lessons and limitations, a cancer perspective.

artículo científico publicado en 2009

Reproductive fitness advantage of BCR-ABL expressing leukemia cells

artículo científico publicado en 2010

Response to salvage therapies and outcome in patients with multiple myeloma relapsing after pomalidomide therapy

artículo científico publicado en 2011

Response to the Editor: On the Growth of Hematopoietic Stem Cells and Childhood Leukemias.

artículo científico publicado en 2016

Retroperitoneal involvement with light chain amyloidosis- case series and literature review

artículo científico publicado en 2020

Revised diagnostic criteria for plasma cell leukemia: results of a Mayo Clinic study with comparison of outcomes to multiple myeloma

scholarly article by Praful Ravi et al published 15 November 2018 in Blood Cancer Journal

Revised prognostic staging system for light chain amyloidosis incorporating cardiac biomarkers and serum free light chain measurements

artículo científico publicado en 2012

Revisiting complete response in light chain amyloidosis

scientific article published on 26 November 2019

Revisiting conditioning dose in newly diagnosed light chain amyloidosis undergoing frontline autologous stem cell transplant: impact on response and survival.

artículo científico publicado en 2017

Risk factors for and outcomes of patients with POEMS syndrome who experience progression after first-line treatment

artículo científico publicado en 2015

Risk stratification in myeloma by detection of circulating plasma cells prior to autologous stem cell transplantation in the novel agent era.

artículo científico publicado en 2016

Risk stratification of smoldering multiple myeloma incorporating revised IMWG diagnostic criteria.

artículo científico publicado en 2018

SCT without growth factor in multiple myeloma: engraftment kinetics, bacteremia and hospitalization

artículo científico publicado en 2010

Safety Outcomes for Autologous Stem Cell Transplant in Multiple Myeloma

artículo científico publicado en 2018

Safety and efficacy of propylene glycol-free melphalan as conditioning in patients with AL amyloidosis undergoing stem cell transplantation

artículo científico publicado en 2018

Schnitzler syndrome: an under-diagnosed clinical entity

artículo científico publicado en 2013

Scleromyxedema

artículo científico publicado en 2014

Second auto-SCT for treatment of relapsed multiple myeloma

artículo científico publicado en 2012

Selective Inhibition of Nuclear Export With Oral Selinexor for Treatment of Relapsed or Refractory Multiple Myeloma.

artículo científico publicado en 2018

Serial measurements of circulating plasma cells before and after induction therapy have an independent prognostic impact in patients with multiple myeloma undergoing upfront autologous transplantation

artículo científico publicado en 2017

Serum M-spike and transplant outcome in patients with multiple myeloma.

artículo científico publicado en 2007

Serum free light chain measurements to reduce 24-h urine monitoring in patients with multiple myeloma with measurable urine monoclonal protein

scientific article published on 15 August 2018

Should tissue structure suppress or amplify selection to minimize cancer risk?

artículo científico publicado en 2016

Smoldering multiple myeloma requiring treatment: time for a new definition?

artículo científico publicado en 2013

Sodium iodide symporter (NIS)-mediated radiovirotherapy for pancreatic cancer

artículo científico publicado en 2010

Soluble suppression of tumorigenicity 2 (sST2), but not galactin-3, adds to prognostication in patients with systemic AL amyloidosis independent of NT-proBNP and troponin T.

artículo científico publicado en 2015

Somatic mutations and the hierarchy of hematopoiesis ⬇️

artículo científico publicado el 27 de agosto de 2010

Some dynamic aspects of hematopoietic stem cells.

artículo científico publicado en 2008

Stem Cell Transplantation for Light Chain Amyloidosis: Decreased Early Mortality Over Time.

artículo científico publicado en 2018

Stem cell transplantation compared with melphalan plus dexamethasone in the treatment of immunoglobulin light-chain amyloidosis

artículo científico publicado en 2016

Stem cell transplantation in multiple myeloma: impact of response failure with thalidomide or lenalidomide induction

artículo científico publicado en 2010

Stem cell transplantation in patients with autonomic neuropathy due to primary (AL) amyloidosis

artículo científico publicado en 2010

Stochastic dynamics and the evolution of mutations in stem cells ⬇️

artículo científico publicado en 2011

Stochastic dynamics of hematopoietic tumor stem cells.

artículo científico publicado en 2007

Successful therapy must eradicate cancer stem cells.

artículo científico publicado en 2006

Survival impact of achieving minimal residual negativity by multi-parametric flow cytometry in AL amyloidosis

scientific article published on 23 September 2019

Systemic Immunoglobulin Light Chain Amyloidosis-Associated Myopathy: Presentation, Diagnostic Pitfalls, and Outcome

artículo científico publicado en 2016

Systemic amyloidosis associated with chronic lymphocytic leukemia/small lymphocytic lymphoma

artículo científico publicado en 2013

Systemic amyloidosis from A (AA) to T (ATTR): a review

scientific article published on 14 September 2020

T-cell large granular lymphocytic leukemia and plasma cell disorders

scholarly article by M Hasib Sidiqi et al published March 2019 in Haematologica

Ten-year survival after autologous stem cell transplantation for immunoglobulin light chain amyloidosis

artículo científico publicado en 2012

Ten-year survivors in AL amyloidosis: characteristics and treatment pattern

scientific article published on 12 July 2019

The allometry of chronic myeloid leukemia

artículo científico publicado en 2009

The ecology of cancer from an evolutionary game theory perspective

artículo científico

The emergence of tumor metastases.

artículo científico publicado en 2007

The impact of dialysis on the survival of patients with immunoglobulin light chain (AL) amyloidosis undergoing autologous stem cell transplantation

artículo científico publicado en 2015

The impact of induction regimen on transplant outcome in newly diagnosed multiple myeloma in the era of novel agents.

artículo científico publicado en 2016

The impact of re-induction prior to salvage autologous stem cell transplantation in multiple myeloma

artículo científico publicado en 2019

The invasion of de-differentiating cancer cells into hierarchical tissues

scientific article published on 01 July 2019

The prognostic significance of CD45 expression by clonal bone marrow plasma cells in patients with newly diagnosed multiple myeloma

artículo científico publicado en 2016

The prognostic significance of polyclonal bone marrow plasma cells in patients with relapsing multiple myeloma

artículo científico publicado en 2017

The prognostic value of multiparametric flow cytometry in AL amyloidosis at diagnosis and at the end of first-line treatment

artículo científico publicado en 2016

The role of bone marrow biopsy in patients with plasma cell disorders: should all patients with a monoclonal protein be biopsied?

scientific article published on 06 May 2020

The utility of plasma vascular endothelial growth factor levels in the diagnosis and follow-up of patients with POEMS syndrome

scientific article published on 31 August 2011

Therapy for Relapsed Multiple Myeloma: Guidelines From the Mayo Stratification for Myeloma and Risk-Adapted Therapy

artículo científico publicado en 2017

Therapy for relapsed multiple myeloma

artículo científico publicado en 2018

Total Red Blood Cell Transfusions for Chronic Hemodialysis Patients in a Single Center, 2009-2013.

artículo científico publicado en 2016

Treatment of Immunoglobulin Light Chain Amyloidosis: Mayo Stratification of Myeloma and Risk-Adapted Therapy (mSMART) Consensus Statement

artículo científico

Treatment patterns and outcome following initial relapse or refractory disease in patients with systemic light chain amyloidosis

artículo científico publicado en 2017

Trend toward improved day 100 and two-year survival following stem cell transplantation for AL: a comparison before and after 2006.

artículo científico publicado en 2011

Trends and outcomes in allogeneic hematopoietic stem cell transplant for multiple myeloma at Mayo Clinic

artículo científico

Trends and outcomes of modern staging of solitary plasmacytoma of bone

artículo científico publicado en 2012

Trends in day 100 and 2-year survival after auto-SCT for AL amyloidosis: outcomes before and after 2006.

artículo científico publicado en 2010

Trends in survival of patients with primary plasma cell leukemia: a population-based analysis

artículo científico publicado en 2014

Trisomies in multiple myeloma: impact on survival in patients with high-risk cytogenetics

artículo científico publicado en 2012

Tumour and immune cell dynamics explain the PSA bounce after prostate cancer brachytherapy

artículo científico publicado en 2016

Tyrosine kinase inhibitor therapy can cure chronic myeloid leukemia without hitting leukemic stem cells

artículo científico publicado en 2009

Unexplained pulmonary hypertension in chronic myeloproliferative disorders

artículo científico publicado en 2001

Use of Beta Blockers is Associated with Survival Outcome of Multiple Myeloma Patients Treated with Pomalidomide

artículo científico publicado en 2020

Utility and prognostic value of 18 F-FDG positron emission tomography-computed tomography scans in patients with newly diagnosed multiple myeloma

artículo científico publicado en 2018

Utility of repeating bone marrow biopsy for confirmation of complete response in multiple myeloma

artículo científico publicado en 2020

Utility of serum free light chain measurements in multiple myeloma patients not achieving complete response to therapy

artículo científico publicado en 2015

Utility of serum free light chain ratio in response definition in patients with multiple myeloma

artículo científico publicado en 2020

Utilization of hematopoietic stem cell transplantation for the treatment of multiple myeloma: a Mayo Stratification of Myeloma and Risk-Adapted Therapy (mSMART) consensus statement.

artículo científico publicado en 2019

Utilizing multiparametric flow cytometry in the diagnosis of patients with primary plasma cell leukemia

artículo científico publicado en 2020

Venetoclax for the treatment of translocation (11;14) AL amyloidosis

scientific article published on 11 May 2020

Venetoclax in a Patient With Light Chain Deposition Disease Secondary to MGRS That Progressed After Kidney Transplantation

artículo científico publicado en 2020

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