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Lista de obras de Martin Schrappe

A case-control study of childhood acute lymphoblastic leukaemia and polymorphisms in the TGF-beta and receptor genes

artículo científico publicado en 2009

A treatment protocol for infants younger than 1 year with acute lymphoblastic leukaemia (Interfant-99): an observational study and a multicentre randomised trial.

artículo científico publicado en 2007

Activating NOTCH1 mutations predict favorable early treatment response and long-term outcome in childhood precursor T-cell lymphoblastic leukemia.

artículo científico publicado en 2006

Activation of concurrent apoptosis and necroptosis by SMAC mimetics for the treatment of refractory and relapsed ALL.

artículo científico publicado en 2016

Acute B lymphoblastic leukaemia-propagating cells are present at high frequency in diverse lymphoblast populations

artículo científico publicado en 2012

Acute leukaemias of ambiguous lineage in children: characterization, prognosis and therapy recommendations

artículo científico publicado en 2010

Acute lymphoblastic leukemia and Klinefelter syndrome in children: two cases and review of the literature

artículo científico publicado en 2004

Acute lymphoblastic leukemia in children with Down syndrome: a retrospective analysis from the Ponte di Legno study group

artículo científico publicado en 2013

Acute lymphoblastic leukemia in children: treatment planning via minimal residual disease assessment

artículo científico

Advances in therapy for Philadelphia-positive acute lymphoblastic leukaemia of childhood and adolescence

artículo científico publicado en 2016

All children have a right to full access to treatment for cancer.

artículo científico publicado en 2004

Allogeneic stem cell transplantation with BEAM and alemtuzumab conditioning immediately after remission induction has curative potential in advanced T-cell non-Hodgkin's lymphoma

artículo científico publicado en 2013

Almost normal cognitive function in patients during therapy for childhood acute lymphoblastic leukemia without cranial irradiation according to ALL-BFM 95 and COALL 06-97 protocols: results of an Austrian-German multicenter longitudinal study and im

artículo científico publicado en 2007

An Fc-engineered CD19 antibody eradicates MRD in patient-derived MLL-rearranged acute lymphoblastic leukemia xenografts

artículo científico publicado en 2017

Analysis of t(9;11) chromosomal breakpoint sequences in childhood acute leukemia: almost identical MLL breakpoints in therapy-related AML after treatment without etoposides

artículo científico publicado en 2003

Author Correction: Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia

scientific article published in Nature Communications

BLUEPRINT to decode the epigenetic signature written in blood.

artículo científico publicado en 2012

CD11b is a therapy resistance- and minimal residual disease-specific marker in precursor B-cell acute lymphoblastic leukemia.

artículo científico publicado en 2010

CRLF2 over-expression is a poor prognostic marker in children with high risk T-cell acute lymphoblastic leukemia

artículo científico publicado en 2016

Central nervous system acute lymphoblastic leukemia: role of natural killer cells

artículo científico publicado en 2015

Challenges for children and adolescents with cancer in Europe: the SIOP-Europe agenda

artículo científico publicado en 2014

Chemotherapy versus allogeneic transplantation for very-high-risk childhood acute lymphoblastic leukaemia in first complete remission: comparison by genetic randomisation in an international prospective study

artículo científico publicado en 2005

Childhood acute lymphoblastic leukemia-associated risk-loci IKZF1, ARID5B and CEBPE and risk of pediatric non-Hodgkin lymphoma: a report from the Berlin-Frankfurt-Münster Study Group.

artículo científico publicado en 2014

Childhood and adolescent lymphoid and myeloid leukemia

artículo científico publicado en 2004

Childhood cancer predisposition syndromes-A concise review and recommendations by the Cancer Predisposition Working Group of the Society for Pediatric Oncology and Hematology.

artículo científico publicado en 2017

Clinical characteristics and treatment outcome of infants with non-Hodgkin lymphoma

artículo científico publicado en 2007

Clinical outcome of children with newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia treated between 1995 and 2005.

artículo científico publicado en 2010

Clinical significance of aberrant DNA methylation in childhood acute lymphoblastic leukemia

artículo científico publicado en 2011

Cloning of genes involved in chromosomal translocations by high-resolution single nucleotide polymorphism genomic microarray

artículo científico publicado en 2008

Consolidation treatment with chimeric anti-GD2-antibody ch14.18 in children older than 1 year with metastatic neuroblastoma

artículo científico publicado en 2004

Copy number alterations in childhood acute lymphoblastic leukemia and their association with minimal residual disease

Creating a unique, multi-stakeholder Paediatric Oncology Platform to improve drug development for children and adolescents with cancer

artículo científico publicado en 2014

DNA methylation profiling of pediatric B-cell lymphoblastic leukemia with KMT2A rearrangement identifies hypomethylation at enhancer sites

artículo científico publicado en 2016

Deficiency of the adaptor SLP-65 in pre-B-cell acute lymphoblastic leukaemia

artículo científico publicado en 2003

Detection and management of minimal residual disease in acute lymphoblastic leukemia

artículo científico publicado en 2014

Detection of minimal residual disease identifies differences in treatment response between T-ALL and precursor B-ALL.

artículo científico publicado en 2002

Detection of residual B precursor lymphoblastic leukemia by uniform gating flow cytometry

artículo científico publicado en 2010

Dexamethasone vs prednisone in induction treatment of pediatric ALL: results of the randomized trial AIEOP-BFM ALL 2000.

artículo científico publicado en 2016

Emergence of translocation t(9;11)-positive leukemia during treatment of childhood acute lymphoblastic leukemia.

artículo científico publicado en 2004

Evaluation of a pediatric liquid formulation to improve 6-mercaptopurine therapy in children

artículo científico publicado en 2015

Expression and structural analysis of glucocorticoid receptor isoform gamma in human leukaemia cells using an isoform-specific real-time polymerase chain reaction approach

artículo científico publicado en 2003

Frequency and clinical relevance of DNA microsatellite alterations of the CDKN2A/B, ATM and p53 gene loci: a comparison between pediatric precursor T-cell lymphoblastic lymphoma and T-cell lymphoblastic leukemia ⬇️

artículo científico publicado en 2009

Frequent and sex-biased deletion of SLX4IP by illegitimate V(D)J-mediated recombination in childhood acute lymphoblastic leukemia.

artículo científico publicado en 2013

GSTP1 and MDR1 genotypes and central nervous system relapse in childhood acute lymphoblastic leukemia

artículo científico publicado en 2005

Gain-of-function mutations in interleukin-7 receptor-α (IL7R) in childhood acute lymphoblastic leukemias ⬇️

artículo científico publicado en 2011

Gain-of-function mutations ininterleukin-7 receptor-α (IL7R) in childhood acute lymphoblastic leukemias

Gene expression patterns associated with recurrent chromosomal translocations in acute lymphoblastic leukemia ⬇️

artículo científico publicado el 2 de octubre de 2003

Genetic polymorphisms of the lymphotoxin alpha gene are associated with increased risk for lethal infections during induction therapy for childhood acute leukemia: a case-control study

artículo científico publicado en 2009

Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia. ⬇️

artículo científico publicado en 2018

Genomics and drug profiling of fatal TCF3-HLF-positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options

artículo científico publicado en 2015

Germline genetic variations in methotrexate candidate genes are associated with pharmacokinetics, toxicity, and outcome in childhood acute lymphoblastic leukemia

artículo científico publicado en 2013

HG-34HIGH-GRADE GLIOMA ARISING IN SURVIVORS OF PEDIATRIC ACUTE LYMPHOBLASTIC MALIGNANCIES: A COOPERATIVE ANALYSIS OF THE GERMAN HIT-HGG/-GBM AND ALL-BFM/COALL STUDIES.

artículo científico publicado en 2016

Heterogeneous expression pattern of pro- and anti-apoptotic factors in myeloid progenitor cells of patients with severe congenital neutropenia treated with granulocyte colony-stimulating factor.

artículo científico publicado en 2005

High CD45 surface expression determines relapse risk in children with precursor B-cell and T-cell acute lymphoblastic leukemia treated according to the ALL-BFM 2000 protocol

artículo científico publicado en 2014

High-resolution genomic profiling of childhood T-ALL reveals frequent copy-number alterations affecting the TGF-beta and PI3K-AKT pathways and deletions at 6q15-16.1 as a genomic marker for unfavorable early treatment response

artículo científico publicado en 2009

IKZF1 deletion is an independent predictor of outcome in pediatric acute lymphoblastic leukemia treated according to the ALL-BFM 2000 protocol

artículo científico publicado en 2012

IKZF1 status as a prognostic feature in BCR-ABL1-positive childhood ALL.

artículo científico publicado en 2014

IKZF1plus Defines a New Minimal Residual Disease-Dependent Very-Poor Prognostic Profile in Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia

artículo científico publicado en 2018

IL7R is associated with CNS infiltration and relapse in pediatric B-cell precursor acute lymphoblastic leukemia

artículo científico publicado en 2018

Ikaros (IKZF1) alterations and minimal residual disease at day 15 assessed by flow cytometry predict prognosis of childhood BCR/ABL-negative acute lymphoblastic leukemia.

artículo científico publicado en 2012

Imatinib after induction for treatment of children and adolescents with Philadelphia-chromosome-positive acute lymphoblastic leukaemia (EsPhALL): a randomised, open-label, intergroup study

artículo científico publicado en 2012

Impact of cranial radiotherapy on central nervous system prophylaxis in children and adolescents with central nervous system-negative stage III or IV lymphoblastic lymphoma

artículo científico publicado en 2006

Implications of delayed bone marrow aspirations at the end of treatment induction for risk stratification and outcome in children with acute lymphoblastic leukaemia

artículo científico publicado en 2016

Improved outcome with hematopoietic stem cell transplantation in a poor prognostic subgroup of infants with mixed-lineage-leukemia (MLL)-rearranged acute lymphoblastic leukemia: results from the Interfant-99 Study.

artículo científico publicado en 2010

In childhood acute lymphoblastic leukemia, blasts at different stages of immunophenotypic maturation have stem cell properties

artículo científico publicado en 2008

In vitro susceptibility to dexamethasone- and doxorubicin-induced apoptotic cell death in context of maturation stage, responsiveness to interleukin 7, and early cytoreduction in vivo in childhood T-cell acute lymphoblastic leukemia.

artículo científico publicado en 2002

Incidence and outcome of TCF3-PBX1-positive acute lymphoblastic leukemia in Austrian children

artículo científico publicado en 2007

Increasing mixed chimerism is an important prognostic factor for unfavorable outcome in children with acute lymphoblastic leukemia after allogeneic stem-cell transplantation: possible role for pre-emptive immunotherapy?

artículo científico publicado en 2004

Influence of Cranial Radiotherapy on Outcome in Children With Acute Lymphoblastic Leukemia Treated With Contemporary Therapy

artículo científico publicado en 2016

Initial leukemic gene expression profiles of patients with poor in vivo prednisone response are similar to those of blasts persisting under prednisone treatment in childhood acute lymphoblastic leukemia

artículo científico publicado en 2008

Integrating molecular information into treatment of childhood acute lymphoblastic leukemia--a perspective from the BFM Study Group

artículo científico publicado en 2007

Intensive chemotherapy for childhood acute lymphoblastic leukemia: results of the randomized intercontinental trial ALL IC-BFM 2002.

artículo científico publicado en 2013

International cooperative study identifies treatment strategy in childhood ambiguous lineage leukemia.

artículo científico publicado en 2018

Kinetics of the in vivo expression of glucocorticoid receptor splice variants during prednisone treatment in childhood acute lymphoblastic leukaemia

artículo científico publicado en 2009

L-asparaginase treatment in acute lymphoblastic leukemia: a focus on Erwinia asparaginase

artículo científico publicado en 2010

Late MRD response determines relapse risk overall and in subsets of childhood T-cell ALL: results of the AIEOP-BFM-ALL 2000 study.

artículo científico publicado en 2011

Leukemic stem cells in childhood high-risk ALL/t(9;22) and t(4;11) are present in primitive lymphoid-restricted CD34+CD19- cells.

artículo científico publicado en 2005

Long non-coding RNAs defining major subtypes of B cell precursor acute lymphoblastic leukemia

scholarly article by Alva Rani James et al published 14 January 2019 in Journal of Hematology & Oncology

Long term outcome of high-risk neuroblastoma patients after immunotherapy with antibody ch14.18 or oral metronomic chemotherapy

artículo científico publicado en 2011

Long term survival in children with acute leukaemia and complications requiring mechanical ventilation

artículo científico publicado en 2011

Long-term follow up of pediatric Philadelphia positive acute lymphoblastic leukemia treated with the EsPhALL2004 study: high white blood cell count at diagnosis is the strongest prognostic factor

scholarly article by Andrea Biondi et al published January 2019 in Haematologica

Long-term outcome in children with relapsed ALL by risk-stratified salvage therapy: results of trial acute lymphoblastic leukemia-relapse study of the Berlin-Frankfurt-Münster Group 87.

artículo científico publicado en 2005

Long-term outcome in children with relapsed acute lymphoblastic leukemia after time-point and site-of-relapse stratification and intensified short-course multidrug chemotherapy: results of trial ALL-REZ BFM 90.

artículo científico publicado en 2010

Low platelet counts after induction therapy for childhood acute lymphoblastic leukemia are strongly associated with poor early response to treatment as measured by minimal residual disease and are prognostic for treatment outcome

artículo científico publicado en 2011

MAP3K7 is recurrently deleted in pediatric T-lymphoblastic leukemia and affects cell proliferation independently of NF-κB.

artículo científico publicado en 2018

Mediastinal mass in childhood T-cell acute lymphoblastic leukemia: significance and therapy response

artículo científico publicado en 2002

Mer tyrosine kinase promotes the survival of t(1;19)-positive acute lymphoblastic leukemia (ALL) in the central nervous system (CNS).

artículo científico publicado en 2014

Methylenetetrahydrofolate reductase (MTHFR) 677C>T polymorphism and risk of pediatric non-Hodgkin lymphoma in a German study population

artículo científico publicado en 2005

Minimal residual disease after induction is the strongest predictor of prognosis in intermediate risk relapsed acute lymphoblastic leukaemia - long-term results of trial ALL-REZ BFM P95/96.

artículo científico publicado en 2012

Minimal residual disease analysis in children with t(12;21)-positive acute lymphoblastic leukemia: comparison of Ig/TCR rearrangements and the genomic fusion gene.

artículo científico publicado en 2006

Minimal residual disease values discriminate between low and high relapse risk in children with B-cell precursor acute lymphoblastic leukemia and an intrachromosomal amplification of chromosome 21: the Austrian and German acute lymphoblastic leukemi

artículo científico publicado en 2008

Minimal residual disease: optimal methods, timing, and clinical relevance for an individual patient

artículo científico

Mitochondrial genome variants in non-remitting ALL of childhood

artículo científico publicado en 2011

Mitoxantrone in first-relapse paediatric ALL: the ALL R3 trial ⬇️

artículo científico publicado el 3 de diciembre de 2010

Molecular allelokaryotyping of pediatric acute lymphoblastic leukemias by high-resolution single nucleotide polymorphism oligonucleotide genomic microarray

artículo científico publicado en 2008

Molecular allelokaryotyping of relapsed pediatric acute lymphoblastic leukemia.

artículo científico publicado en 2009

Molecular characterization of acute lymphoblastic leukemia with high CRLF2 gene expression in childhood

artículo científico publicado en 2017

Molecular response to treatment redefines all prognostic factors in children and adolescents with B-cell precursor acute lymphoblastic leukemia: results in 3184 patients of the AIEOP-BFM ALL 2000 study

artículo científico publicado en 2010

Monitoring of minimal residual disease after allogeneic stem-cell transplantation in relapsed childhood acute lymphoblastic leukemia allows for the identification of impending relapse: results of the ALL-BFM-SCT 2003 trial

artículo científico publicado en 2015

Mutations of JAK2 in acute lymphoblastic leukaemias associated with Down's syndrome

artículo científico publicado en 2008

Myeloablative megatherapy with autologous stem-cell rescue versus oral maintenance chemotherapy as consolidation treatment in patients with high-risk neuroblastoma: a randomised controlled trial

artículo científico publicado en 2005

NGS-based methylation profiling differentiates TCF3-HLF and TCF3-PBX1 positive B-cell acute lymphoblastic leukemia

artículo científico publicado en 2018

NOTCH1 activation clinically antagonizes the unfavorable effect of PTEN inactivation in BFM-treated children with precursor T-cell acute lymphoblastic leukemia

artículo científico publicado en 2013

Neurotoxic side effects in children with refractory or relapsed T-cell malignancies treated with nelarabine based therapy

artículo científico publicado en 2017

New treatment strategies in childhood acute lymphoblastic leukaemia

artículo científico publicado en 2002

No association between the presence of killer-cell immunoglobulin-like receptor genes and susceptibility to childhood ALL.

artículo científico publicado en 2015

Optimizing asparaginase therapy for acute lymphoblastic leukemia

artículo científico

Osteonecrosis develops independently from radiological leukemic infiltration of bone in adolescents with acute lymphoblastic leukemia - first findings of the OPAL trial

artículo científico publicado en 2017

Osteonecrosis: a treatment related toxicity in childhood acute lymphoblastic leukemia (ALL)--experiences from trial ALL-BFM 95.

artículo científico publicado en 2005

Outcome of relapse after allogeneic HSCT in children with ALL enrolled in the ALL-SCT 2003/2007 trial

artículo científico publicado en 2017

Outcome of treatment in children with hypodiploid acute lymphoblastic leukemia

artículo científico publicado en 2007

Outcomes after induction failure in childhood acute lymphoblastic leukemia

artículo científico publicado en 2012

Outcomes of treatment for relapsed acute lymphoblastic leukaemia in children with Down syndrome

artículo científico publicado en 2013

PEG-asparaginase (Oncaspar) 2500 U/m(2) BSA in reinduction and relapse treatment in the ALL/NHL-BFM protocols.

artículo científico publicado en 2001

Pharmacokinetics of high-dose methotrexate in infants treated for acute lymphoblastic leukemia

artículo científico publicado en 2009

Phase II window study on rituximab in newly diagnosed pediatric mature B-cell non-Hodgkin's lymphoma and Burkitt leukemia

artículo científico publicado en 2010

Polymorphisms of methylenetetrahydrofolate reductase (MTHFR) and susceptibility to pediatric acute lymphoblastic leukemia in a German study population

artículo científico publicado en 2005

Polymorphisms within glutathione S-transferase genes in pediatric non-Hodgkin's lymphoma.

artículo científico publicado en 2002

Population Pharmacokinetics to Model the Time-Varying Clearance of the PEGylated Asparaginase Oncaspar® in Children with Acute Lymphoblastic Leukemia

artículo científico publicado en 2017

Prediction of outcome by early bone marrow response in childhood acute lymphoblastic leukemia treated in the ALL-BFM 95 trial: differential effects in precursor B-cell and T-cell leukemia

artículo científico publicado en 2012

Predictive value of minimal residual disease in Philadelphia-chromosome-positive acute lymphoblastic leukemia treated with imatinib in the European intergroup study of post-induction treatment of Philadelphia-chromosome-positive acute lymphoblastic l

scholarly article by Giovanni Cazzaniga et al published January 2018 in Haematologica

Prevalence, clinical pattern, and outcome of CNS involvement in childhood and adolescent non-Hodgkin's lymphoma differ by non-Hodgkin's lymphoma subtype: a Berlin-Frankfurt-Munster Group Report.

artículo científico publicado en 2007

Prognostic relevance of TLX3 (HOX11L2) expression in childhood T-cell acute lymphoblastic leukaemia treated with Berlin-Frankfurt-Münster (BFM) protocols containing early and late re-intensification elements

artículo científico publicado en 2009

Prognostic relevance of dic(9;20)(p11;q13) in childhood B-cell precursor acute lymphoblastic leukaemia treated with Berlin-Frankfurt-Münster (BFM) protocols containing an intensive induction and post-induction consolidation therapy

artículo científico publicado en 2010

Promising therapy results for lymphoid malignancies in children with chromosomal breakage syndromes (Ataxia teleangiectasia or Nijmegen-breakage syndrome): a retrospective survey.

artículo científico publicado en 2011

Protein expression of the glucocorticoid receptor in childhood acute lymphoblastic leukemia ⬇️

artículo científico publicado el 1 de noviembre de 2003

Protocol II vs protocol III given twice during reinduction therapy in children with medium-risk ALL.

artículo científico publicado en 2017

Pulses of vincristine and dexamethasone in addition to intensive chemotherapy for children with intermediate-risk acute lymphoblastic leukaemia: a multicentre randomised trial

artículo científico

Quantification of free total plasma DNA and minimal residual disease detection in the plasma of children with acute lymphoblastic leukemia.

artículo científico publicado en 2009

RSK-mediated nuclear accumulation of the cold-shock Y-box protein-1 controls proliferation of T cells and T-ALL blasts

artículo científico publicado en 2016

Rationale for an international consortium to study inherited genetic susceptibility to childhood acute lymphoblastic leukemia

artículo científico publicado en 2011

Reduced-Intensity Delayed Intensification in Standard-Risk Pediatric Acute Lymphoblastic Leukemia Defined by Undetectable Minimal Residual Disease: Results of an International Randomized Trial (AIEOP-BFM ALL 2000).

artículo científico publicado en 2017

Relevance of ID3-TCF3-CCND3 pathway mutations in pediatric aggressive B-cell lymphoma treated according to the non-Hodgkin Lymphoma Berlin-Frankfurt-Münster protocols

artículo científico publicado en 2017

Results and conclusions of the European Intergroup EURO-LB02 trial in children and adolescents with lymphoblastic lymphoma

artículo científico publicado en 2017

Risk assessment of relapse by lineage-specific monitoring of chimerism in children undergoing allogeneic stem cell transplantation for acute lymphoblastic leukemia

artículo científico publicado en 2016

Risk-adapted stratification and treatment of childhood acute lymphoblastic leukaemia

artículo científico publicado en 2008

Risk-adjusted therapy of acute lymphoblastic leukemia can decrease treatment burden and improve survival: treatment results of 2169 unselected pediatric and adolescent patients enrolled in the trial ALL-BFM 95.

artículo científico publicado en 2008

Secondary histiocytic sarcoma may cause apparent persistence or recurrence of minimal residual disease in childhood acute lymphoblastic leukemia

artículo científico

Stem-cell transplantation in children with acute lymphoblastic leukemia: A prospective international multicenter trial comparing sibling donors with matched unrelated donors-The ALL-SCT-BFM-2003 trial

artículo científico publicado en 2015

Superiority of allogeneic hematopoietic stem-cell transplantation compared with chemotherapy alone in high-risk childhood T-cell acute lymphoblastic leukemia: results from ALL-BFM 90 and 95.

artículo científico publicado en 2006

Suppressors and activators of JAK-STAT signaling at diagnosis and relapse of acute lymphoblastic leukemia in Down syndrome

artículo científico publicado en 2017

T-cell acute lymphoblastic leukemia in infants has distinct genetic and epigenetic features compared to childhood cases

artículo científico publicado en 2016

THROMBOTECT – a randomized study comparing low molecular weight heparin, antithrombin and unfractionated heparin for thromboprophylaxis during induction therapy of acute lymphoblastic leukemia in children and adolescents

scholarly article by Jeanette Greiner et al published 27 September 2018 in Haematologica

The 9p21.3 risk of childhood acute lymphoblastic leukaemia is explained by a rare high-impact variant in CDKN2A ⬇️

artículo científico publicado en 2015

The NQO1 C609T polymorphism is associated with risk of secondary malignant neoplasms after treatment for childhood acute lymphoblastic leukemia: a matched-pair analysis from the ALL-BFM study group

artículo científico publicado en 2007

The SIOPE strategic plan: A European cancer plan for children and adolescents

The impact of age and gender on biology, clinical features and treatment outcome of non-Hodgkin lymphoma in childhood and adolescence

artículo científico publicado en 2005

The impact of the methotrexate administration schedule and dose in the treatment of children and adolescents with B-cell neoplasms: a report of the BFM Group Study NHL-BFM95.

artículo científico publicado en 2004

The role of ZAP70 kinase in acute lymphoblastic leukemia infiltration into the central nervous system

artículo científico publicado en 2016

The role of constitutive activation of FMS-related tyrosine kinase-3 and NRas/KRas mutational status in infants with KMT2A-rearranged acute lymphoblastic leukemia

artículo científico publicado en 2017

Therapeutic Drug Monitoring of Asparaginase Activity-Method Comparison of MAAT and AHA Test Used in the International AIEOP-BFM ALL 2009 Trial

artículo científico publicado en 2017

Therapeutic drug monitoring of asparaginase in the ALL-BFM 2000 protocol between 2000 and 2007.

artículo científico publicado en 2010

Thiopurine methyltransferase (TPMT) genotype and early treatment response to mercaptopurine in childhood acute lymphoblastic leukemia

artículo científico publicado en 2005

Thiopurine methyltransferase genetics is not a major risk factor for secondary malignant neoplasms after treatment of childhood acute lymphoblastic leukemia on Berlin-Frankfurt-Münster protocols.

artículo científico publicado en 2009

Time point-dependent concordance of flow cytometry and real-time quantitative polymerase chain reaction for minimal residual disease detection in childhood acute lymphoblastic leukemia

artículo científico publicado en 2012

Treatment of childhood acute lymphoblastic leukemia

scientific article published on January 2009

Treatment outcome of CRLF2-rearranged childhood acute lymphoblastic leukaemia: a comparative analysis of the AIEOP-BFM and UK NCRI-CCLG study groups

artículo científico publicado en 2012

Tumor necrosis factor and lymphotoxin-alpha genetic polymorphisms and risk of relapse in childhood B-cell precursor acute lymphoblastic leukemia: a case-control study of patients treated with BFM therapy

artículo científico publicado en 2001

Use of allogeneic hematopoietic stem-cell transplantation based on minimal residual disease response improves outcomes for children with relapsed acute lymphoblastic leukemia in the intermediate-risk group

artículo científico publicado en 2013

Variation at 10p12.2 and 10p14 influences risk of childhood B-cell acute lymphoblastic leukemia and phenotype

scientific journal article

Variation in CDKN2A at 9p21.3 influences childhood acute lymphoblastic leukemia risk

artículo científico publicado en 2010

Verification of the susceptibility loci on 7p12.2, 10q21.2, and 14q11.2 in precursor B-cell acute lymphoblastic leukemia of childhood.

artículo científico publicado en 2009

XIAP variants in male Crohn's disease.

artículo científico publicado en 2014

Xenografts of highly resistant leukemia recapitulate the clonal composition of the leukemogenic compartment.

artículo científico publicado en 2011

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