Lista de obras -

A high-risk signature for patients with multiple myeloma established from the molecular classification of human myeloma cell lines

artículo científico publicado en 2010

A magnetic resonance imaging-based prognostic scoring system to predict outcome in transplant-eligible patients with multiple myeloma

artículo científico publicado en 2015

A new method for class prediction based on signed-rank algorithms applied to Affymetrix microarray experiments

artículo científico publicado en 2008

A tissue-based approach to selection of reference genes for quantitative real-time PCR in a sheep osteoporosis model

artículo científico publicado en 2017

Antigen-mediated regulation in monoclonal gammopathies and myeloma.

artículo científico publicado en 2018

Association between magnetic resonance imaging patterns and baseline disease features in multiple myeloma: analyzing surrogates of tumour mass and biology

artículo científico publicado en 2016

Autologous retransplantation for patients with recurrent multiple myeloma: a single-center experience with 200 patients.

artículo científico publicado en 2013

Baseline characteristics, chromosomal alterations, and treatment affecting prognosis of deletion 17p in newly diagnosed myeloma

artículo científico publicado en 2016

Bone marrow stromal cell interaction reduces syndecan-1 expression and induces kinomic changes in myeloma cells

artículo científico publicado en 2010

Bortezomib induction and maintenance treatment in patients with newly diagnosed multiple myeloma: results of the randomized phase III HOVON-65/ GMMG-HD4 trial.

artículo científico publicado en 2012

CD200 is a new prognostic factor in multiple myeloma

artículo científico publicado en 2006

CD24, CD27, CD36 and CD302 gene expression for outcome prediction in patients with multiple myeloma

artículo científico publicado en 2017

Cellular uptake kinetics of bortezomib in relation to efficacy in myeloma cells and the influence of drug transporters

artículo científico publicado en 2014

Cereblon-binding proteins expression levels correlate with hyperdiploidy in newly diagnosed multiple myeloma patients

scholarly article by Katharina Kriegsmann et al published 29 January 2019 in Blood Cancer Journal

Changes in magnetic resonance imaging before and after autologous stem cell transplantation correlate with response and survival in multiple myeloma

artículo científico publicado en 2012

Characterization of a transitional preplasmablast population in the process of human B cell to plasma cell differentiation

artículo científico publicado en 2011

Chetomin, targeting HIF-1α/p300 complex, exhibits antitumour activity in multiple myeloma

artículo científico publicado en 2016

Combining information regarding chromosomal aberrations t(4;14) and del(17p13) with the International Staging System classification allows stratification of myeloma patients undergoing autologous stem cell transplantation

artículo científico publicado en 2010

Common variation at 3q26.2, 6p21.33, 17p11.2 and 22q13.1 influences multiple myeloma risk

scientific journal article

Concomitant gain of 1q21 and MYC translocation define a poor prognostic subgroup of hyperdiploid multiple myeloma

artículo científico publicado en 2015

Cytogenetic intraclonal heterogeneity of plasma cell dyscrasia in AL amyloidosis as compared with multiple myeloma

artículo científico publicado en 2018

DNA methylation score is predictive of myeloma cell sensitivity to 5-azacitidine

artículo científico publicado en 2013

DNA repair pathways in human multiple myeloma: role in oncogenesis and potential targets for treatment

artículo científico publicado en 2013

DNMTi/HDACi combined epigenetic targeted treatment induces reprogramming of myeloma cells in the direction of normal plasma cells.

artículo científico publicado en 2018

Dendritic Glycopolymer as Drug Delivery System for Proteasome Inhibitor Bortezomib in a Calcium Phosphate Bone Cement: First Steps Toward a Local Therapy of Osteolytic Bone Lesions.

artículo científico publicado en 2015

Development of gene expression-based score to predict sensitivity of multiple myeloma cells to DNA methylation inhibitors

artículo científico publicado en 2012

Drug Release as a function of bioactivity, incubation regime, liquid, and initial load: Release of bortezomib from calcium phosphate-containing silica/collagen xerogels

artículo científico publicado en 2017

Drug metabolism and clearance system in tumor cells of patients with multiple myeloma

artículo científico publicado en 2015

Expression of EGF-family receptors and amphiregulin in multiple myeloma. Amphiregulin is a growth factor for myeloma cells

artículo científico publicado en 2005

Expression of genes encoding for proteins involved in heparan sulphate and chondroitin sulphate chain synthesis and modification in normal and malignant plasma cells

artículo científico publicado en 2009

Forced KLF4 expression increases the generation of mature plasma cells and uncovers a network linked with plasma cell stage

artículo científico publicado en 2016

From Bench to Bedside: A View on Bioinformatics Pipelines

artículo científico publicado en 2017

Gain of chromosome 1q21 is an independent adverse prognostic factor in light chain amyloidosis patients treated with melphalan/dexamethasone

article by Tilmann Bochtler et al published 23 January 2014 in Amyloid

Gene expression of anti- and pro-apoptotic proteins in malignant and normal plasma cells

artículo científico publicado en 2009

Gene expression profiling and real-time PCR analyses identify novel potential cancer-testis antigens in multiple myeloma

artículo científico publicado en 2009

Gene expression profiling for molecular classification of multiple myeloma in newly diagnosed patients

artículo científico publicado en 2010

Gene expression profiling in multiple myeloma--reporting of entities, risk, and targets in clinical routine

artículo científico publicado en 2011

Genes with a spike expression are clustered in chromosome (sub)bands and spike (sub)bands have a powerful prognostic value in patients with multiple myeloma

artículo científico publicado en 2011

GenomicScape: an easy-to-use web tool for gene expression data analysis. Application to investigate the molecular events in the differentiation of B cells into plasma cells

artículo científico publicado en 2015

Growth factors in multiple myeloma: a comprehensive analysis of their expression in tumor cells and bone marrow environment using Affymetrix microarrays

artículo científico publicado en 2010

Heparanase influences expression and shedding of syndecan-1, and its expression by the bone marrow environment is a bad prognostic factor in multiple myeloma

artículo científico publicado en 2007

High cereblon expression is associated with better survival in patients with newly diagnosed multiple myeloma treated with thalidomide maintenance.

artículo científico publicado en 2012

Human reaming debris: a source of multipotent stem cells

artículo científico publicado en 2004

Hyperdiploidy is less frequent in AL amyloidosis compared with monoclonal gammopathy of undetermined significance and inversely associated with translocation t(11;14).

artículo científico publicado en 2011

Identification of HLA-A2 restricted T-cell epitopes within the conserved region of the immunoglobulin G heavy-chain in patients with multiple myeloma

scientific article published on 19 March 2008

Identification of a new HLA-A2-restricted T-cell epitope within HM1.24 as immunotherapy target for multiple myeloma

artículo científico publicado en 2006

Identification of pluripotent and adult stem cell genes unrelated to cell cycle and associated with poor prognosis in multiple myeloma

artículo científico publicado en 2012

Immunochemical, ultrastructural and electrophysiological investigations of bone-derived stem cells in the course of neuronal differentiation

artículo científico publicado en 2006

Immunomodulatory drugs thalidomide and lenalidomide affect osteoblast differentiation of human bone marrow stromal cells in vitro.

artículo científico publicado en 2014

Inherited genetic susceptibility to monoclonal gammopathy of unknown significance

artículo científico publicado en 2014

Inhibiting the anaphase promoting complex/cyclosome induces a metaphase arrest and cell death in multiple myeloma cells

artículo científico publicado en 2015

Inhibition of DEPDC1A, a bad prognostic marker in multiple myeloma, delays growth and induces mature plasma cell markers in malignant plasma cells

artículo científico publicado en 2013

Inhibition of aurora kinases for tailored risk-adapted treatment of multiple myeloma

artículo científico publicado en 2009

Insulin like growth factor binding protein 7 (IGFBP7) expression is linked to poor prognosis but may protect from bone disease in multiple myeloma

artículo científico publicado en 2015

Krüppel-like factor 4 blocks tumor cell proliferation and promotes drug resistance in multiple myeloma

artículo científico publicado en 2013

Lenalidomide enhances antigen-specific activity and decreases CD45RA expression of T cells from patients with multiple myeloma

artículo científico publicado en 2011

Lenalidomide enhances myeloma-specific T-cell responses in vivo and in vitro

artículo científico publicado en 2016

MYEOV is a prognostic factor in multiple myeloma

artículo científico publicado en 2010

Melan-A/MART1 analog peptide triggers anti-myeloma T-cells through crossreactivity with HM1.24.

artículo científico publicado en 2009

Microarray-based understanding of normal and malignant plasma cells

artículo científico publicado en 2006

Modeling risk stratification in human cancer

artículo científico publicado en 2013

Molecular pathogenesis of multiple myeloma: chromosomal aberrations, changes in gene expression, cytokine networks, and the bone marrow microenvironment

scientific article published on January 2011

Novel recurrent chromosomal aberrations detected in clonal plasma cells of light chain amyloidosis patients show potential adverse prognostic effect: first results from a genome-wide copy number array analysis

artículo científico publicado en 2017

Osteoclast-gene expression profiling reveals osteoclast-derived CCR2 chemokines promoting myeloma cell migration

artículo científico publicado en 2010

Prognostic impact of cytogenetic aberrations in AL amyloidosis patients after high-dose melphalan: a long-term follow-up study

artículo científico publicado en 2016

Prognostic significance of increased bone marrow microcirculation in newly diagnosed multiple myeloma: results of a prospective DCE-MRI study

artículo científico publicado en 2015

Progression in smoldering myeloma is independently determined by the chromosomal abnormalities del(17p), t(4;14), gain 1q, hyperdiploidy, and tumor load

artículo científico publicado en 2013

Proliferation is a central independent prognostic factor and target for personalized and risk-adapted treatment in multiple myeloma

artículo científico publicado en 2010

Quantification of plasma cell dynamics using mathematical modelling

artículo científico publicado en 2018

Rationale and design of the German-speaking myeloma multicenter group (GMMG) trial HD6: a randomized phase III trial on the effect of elotuzumab in VRD induction/consolidation and lenalidomide maintenance in patients with newly diagnosed myeloma

article

Report of the European Myeloma Network on multiparametric flow cytometry in multiple myeloma and related disorders

scientific article published on 11 February 2008

STEAP1 is overexpressed in cancers: a promising therapeutic target

artículo científico publicado en 2012

Sorafenib in patients with refractory or recurrent multiple myeloma

artículo científico publicado en 2013

Stability of the proteasome inhibitor bortezomib in cell based assays determined by ultra-high performance liquid chromatography coupled to tandem mass spectrometry

T cell-based targeted immunotherapies for patients with multiple myeloma

artículo científico

Targeting NF-kappaB pathway with an IKK2 inhibitor induces inhibition of multiple myeloma cell growth

artículo científico publicado en 2007

Thalidomide maintenance therapy maturates the T cell compartment and compromises antigen-specific antitumor immunity in patients with multiple myeloma

artículo científico publicado en 2012

The 7p15.3 (rs4487645) association for multiple myeloma shows strong allele-specific regulation of the MYC-interacting gene CDCA7L in malignant plasma cells

artículo científico publicado en 2014

The CCND1 c.870G>A polymorphism is a risk factor for t(11;14)(q13;q32) multiple myeloma

artículo científico publicado en 2013

The glycome of normal and malignant plasma cells

artículo científico publicado en 2013

The role of IGF-1 as a major growth factor for myeloma cell lines and the prognostic relevance of the expression of its receptor

artículo científico publicado en 2009

Thymosin beta4 in multiple myeloma: friend or foe.

artículo científico publicado en 2010

Thymosin β4 has tumor suppressive effects and its decreased expression results in poor prognosis and decreased survival in multiple myeloma

artículo científico publicado en 2009

Timing of the high-dose therapy in the area of new drugs.

artículo científico publicado en 2011

Translocation t(11;14) is associated with adverse outcome in patients with newly diagnosed AL amyloidosis when treated with bortezomib-based regimens

artículo científico publicado en 2015

Tumor cells in multiple myeloma patients inhibit myeloma-reactive T cells through carcinoembryonic antigen-related cell adhesion molecule-6.

artículo científico publicado en 2013

miRNAs in multiple myeloma--a survival relevant complex regulator of gene expression

artículo científico

Lista de obras de

A high-risk signature for patients with multiple myeloma established from the molecular classification of human myeloma cell lines

A magnetic resonance imaging-based prognostic scoring system to predict outcome in transplant-eligible patients with multiple myeloma

A new method for class prediction based on signed-rank algorithms applied to Affymetrix microarray experiments

A tissue-based approach to selection of reference genes for quantitative real-time PCR in a sheep osteoporosis model

Antigen-mediated regulation in monoclonal gammopathies and myeloma.

Association between magnetic resonance imaging patterns and baseline disease features in multiple myeloma: analyzing surrogates of tumour mass and biology

Autologous retransplantation for patients with recurrent multiple myeloma: a single-center experience with 200 patients.

Baseline characteristics, chromosomal alterations, and treatment affecting prognosis of deletion 17p in newly diagnosed myeloma

Bone marrow stromal cell interaction reduces syndecan-1 expression and induces kinomic changes in myeloma cells

Bortezomib induction and maintenance treatment in patients with newly diagnosed multiple myeloma: results of the randomized phase III HOVON-65/ GMMG-HD4 trial.

CD200 is a new prognostic factor in multiple myeloma

CD24, CD27, CD36 and CD302 gene expression for outcome prediction in patients with multiple myeloma

Cellular uptake kinetics of bortezomib in relation to efficacy in myeloma cells and the influence of drug transporters

Cereblon-binding proteins expression levels correlate with hyperdiploidy in newly diagnosed multiple myeloma patients

Changes in magnetic resonance imaging before and after autologous stem cell transplantation correlate with response and survival in multiple myeloma

Characterization of a transitional preplasmablast population in the process of human B cell to plasma cell differentiation

Chetomin, targeting HIF-1α/p300 complex, exhibits antitumour activity in multiple myeloma

Combining information regarding chromosomal aberrations t(4;14) and del(17p13) with the International Staging System classification allows stratification of myeloma patients undergoing autologous stem cell transplantation

Common variation at 3q26.2, 6p21.33, 17p11.2 and 22q13.1 influences multiple myeloma risk

Concomitant gain of 1q21 and MYC translocation define a poor prognostic subgroup of hyperdiploid multiple myeloma

Cytogenetic intraclonal heterogeneity of plasma cell dyscrasia in AL amyloidosis as compared with multiple myeloma

DNA methylation score is predictive of myeloma cell sensitivity to 5-azacitidine

DNA repair pathways in human multiple myeloma: role in oncogenesis and potential targets for treatment

DNMTi/HDACi combined epigenetic targeted treatment induces reprogramming of myeloma cells in the direction of normal plasma cells.

Dendritic Glycopolymer as Drug Delivery System for Proteasome Inhibitor Bortezomib in a Calcium Phosphate Bone Cement: First Steps Toward a Local Therapy of Osteolytic Bone Lesions.

Development of gene expression-based score to predict sensitivity of multiple myeloma cells to DNA methylation inhibitors

Drug Release as a function of bioactivity, incubation regime, liquid, and initial load: Release of bortezomib from calcium phosphate-containing silica/collagen xerogels

Drug metabolism and clearance system in tumor cells of patients with multiple myeloma

Expression of EGF-family receptors and amphiregulin in multiple myeloma. Amphiregulin is a growth factor for myeloma cells

Expression of genes encoding for proteins involved in heparan sulphate and chondroitin sulphate chain synthesis and modification in normal and malignant plasma cells

Forced KLF4 expression increases the generation of mature plasma cells and uncovers a network linked with plasma cell stage

From Bench to Bedside: A View on Bioinformatics Pipelines

Gain of chromosome 1q21 is an independent adverse prognostic factor in light chain amyloidosis patients treated with melphalan/dexamethasone

Gene expression of anti- and pro-apoptotic proteins in malignant and normal plasma cells

Gene expression profiling and real-time PCR analyses identify novel potential cancer-testis antigens in multiple myeloma

Gene expression profiling for molecular classification of multiple myeloma in newly diagnosed patients

Gene expression profiling in multiple myeloma--reporting of entities, risk, and targets in clinical routine

Genes with a spike expression are clustered in chromosome (sub)bands and spike (sub)bands have a powerful prognostic value in patients with multiple myeloma

GenomicScape: an easy-to-use web tool for gene expression data analysis. Application to investigate the molecular events in the differentiation of B cells into plasma cells

Growth factors in multiple myeloma: a comprehensive analysis of their expression in tumor cells and bone marrow environment using Affymetrix microarrays

Heparanase influences expression and shedding of syndecan-1, and its expression by the bone marrow environment is a bad prognostic factor in multiple myeloma

High cereblon expression is associated with better survival in patients with newly diagnosed multiple myeloma treated with thalidomide maintenance.

Human reaming debris: a source of multipotent stem cells

Hyperdiploidy is less frequent in AL amyloidosis compared with monoclonal gammopathy of undetermined significance and inversely associated with translocation t(11;14).

Identification of HLA-A2 restricted T-cell epitopes within the conserved region of the immunoglobulin G heavy-chain in patients with multiple myeloma

Identification of a new HLA-A2-restricted T-cell epitope within HM1.24 as immunotherapy target for multiple myeloma

Identification of pluripotent and adult stem cell genes unrelated to cell cycle and associated with poor prognosis in multiple myeloma

Immunochemical, ultrastructural and electrophysiological investigations of bone-derived stem cells in the course of neuronal differentiation

Immunomodulatory drugs thalidomide and lenalidomide affect osteoblast differentiation of human bone marrow stromal cells in vitro.

Inherited genetic susceptibility to monoclonal gammopathy of unknown significance

Inhibiting the anaphase promoting complex/cyclosome induces a metaphase arrest and cell death in multiple myeloma cells

Inhibition of DEPDC1A, a bad prognostic marker in multiple myeloma, delays growth and induces mature plasma cell markers in malignant plasma cells

Inhibition of aurora kinases for tailored risk-adapted treatment of multiple myeloma

Insulin like growth factor binding protein 7 (IGFBP7) expression is linked to poor prognosis but may protect from bone disease in multiple myeloma

Krüppel-like factor 4 blocks tumor cell proliferation and promotes drug resistance in multiple myeloma

Lenalidomide enhances antigen-specific activity and decreases CD45RA expression of T cells from patients with multiple myeloma

Lenalidomide enhances myeloma-specific T-cell responses in vivo and in vitro

MYEOV is a prognostic factor in multiple myeloma

Melan-A/MART1 analog peptide triggers anti-myeloma T-cells through crossreactivity with HM1.24.

Microarray-based understanding of normal and malignant plasma cells

Modeling risk stratification in human cancer

Molecular pathogenesis of multiple myeloma: chromosomal aberrations, changes in gene expression, cytokine networks, and the bone marrow microenvironment

Novel recurrent chromosomal aberrations detected in clonal plasma cells of light chain amyloidosis patients show potential adverse prognostic effect: first results from a genome-wide copy number array analysis

Osteoclast-gene expression profiling reveals osteoclast-derived CCR2 chemokines promoting myeloma cell migration

Prognostic impact of cytogenetic aberrations in AL amyloidosis patients after high-dose melphalan: a long-term follow-up study

Prognostic significance of increased bone marrow microcirculation in newly diagnosed multiple myeloma: results of a prospective DCE-MRI study

Progression in smoldering myeloma is independently determined by the chromosomal abnormalities del(17p), t(4;14), gain 1q, hyperdiploidy, and tumor load

Proliferation is a central independent prognostic factor and target for personalized and risk-adapted treatment in multiple myeloma

Quantification of plasma cell dynamics using mathematical modelling

Rationale and design of the German-speaking myeloma multicenter group (GMMG) trial HD6: a randomized phase III trial on the effect of elotuzumab in VRD induction/consolidation and lenalidomide maintenance in patients with newly diagnosed myeloma

Report of the European Myeloma Network on multiparametric flow cytometry in multiple myeloma and related disorders

STEAP1 is overexpressed in cancers: a promising therapeutic target

Sorafenib in patients with refractory or recurrent multiple myeloma

Stability of the proteasome inhibitor bortezomib in cell based assays determined by ultra-high performance liquid chromatography coupled to tandem mass spectrometry

T cell-based targeted immunotherapies for patients with multiple myeloma

Targeting NF-kappaB pathway with an IKK2 inhibitor induces inhibition of multiple myeloma cell growth

Thalidomide maintenance therapy maturates the T cell compartment and compromises antigen-specific antitumor immunity in patients with multiple myeloma

The 7p15.3 (rs4487645) association for multiple myeloma shows strong allele-specific regulation of the MYC-interacting gene CDCA7L in malignant plasma cells

The CCND1 c.870G>A polymorphism is a risk factor for t(11;14)(q13;q32) multiple myeloma