Lista de obras -

A new model for post-integration latency in macroglial cells to study HIV-1 reservoirs of the brain

artículo científico publicado en 2015

AML with gain of chromosome 8 as the sole chromosomal abnormality (+8sole) is associated with a specific molecular mutation pattern including ASXL1 mutations in 46.8% of the patients

artículo científico publicado en 2014

ASXL2 regulates hematopoiesis in mice and its deficiency promotes myeloid expansion

scholarly article by Vikas Madan et al published 9 August 2018 in Haematologica

Application of an NGS-based 28-gene panel in myeloproliferative neoplasms reveals distinct mutation patterns in essential thrombocythaemia, primary myelofibrosis and polycythaemia vera

artículo científico publicado en 2016

Comprehensive mutational profiling in advanced systemic mastocytosis

artículo científico publicado en 2013

Detection and characterization of homozygosity of mutated by copy neutral loss of heterozygosity in myeloproliferative neoplasms among cases with high mutation loads or with progressive disease

scholarly article by Anna Stengel et al published 8 November 2018 in Haematologica

Detection of recurrent and of novel fusion transcripts in myeloid malignancies by targeted RNA sequencing

artículo científico publicado en 2018

Dynamics of clonal evolution in myelodysplastic syndromes

artículo científico publicado en 2016

Efficacy of azacitidine is independent of molecular and clinical characteristics - an analysis of 128 patients with myelodysplastic syndromes or acute myeloid leukemia and a review of the literature.

artículo científico publicado en 2018

Functional nuclear topography of transcriptionally inducible extra-chromosomal transgene clusters

artículo científico publicado en 2010

IDH1-R132 changes vary according to NPM1 and other mutations status in AML.

artículo científico publicado en 2019

IDH1R132, IDH2R140 and IDH2R172 in AML: different genetic landscapes correlate with outcome and may influence targeted treatment strategies.

artículo científico publicado en 2018

Incidence and prognostic impact of cytogenetic aberrations in patients with systemic mastocytosis

artículo científico publicado en 2018

Integrating clinical features and genetic lesions in the risk assessment of patients with chronic myelomonocytic leukemia

artículo científico publicado en 2016

Karyotype evolution and acquisition of FLT3 or RAS pathway alterations drive progression of myelodysplastic syndrome to acute myeloid leukemia

artículo científico publicado en 2015

Molecular analysis of myelodysplastic syndrome with isolated deletion of the long arm of chromosome 5 reveals a specific spectrum of molecular mutations with prognostic impact: a study on 123 patients and 27 genes

artículo científico publicado en 2017

Molecular subtypes of NPM1 mutations have different clinical profiles, specific patterns of accompanying molecular mutations and varying outcomes in intermediate risk acute myeloid leukemia

artículo científico publicado en 2015

Mutational hierarchies in myelodysplastic syndromes dynamically adapt and evolve upon therapy response and failure

artículo científico publicado en 2016

RAS signaling promotes resistance to JAK inhibitors by suppressing BAD-mediated apoptosis

artículo científico publicado en 2014

Recurrent CDKN1B (p27) mutations in hairy cell leukemia

artículo científico publicado en 2015

Refractory anemia with ring sideroblasts and marked thrombocytosis cases harbor mutations in SF3B1 or other spliceosome genes accompanied by JAK2V617F and ASXL1 mutations

artículo científico publicado en 2014

Response and progression on midostaurin in advanced systemic mastocytosis: KIT D816V and other molecular markers

artículo científico publicado en 2017

SRSF2 mutations in 275 cases with chronic myelomonocytic leukemia (CMML)

artículo científico publicado en 2012

Specific molecular mutation patterns delineate chronic neutrophilic leukemia, atypical chronic myeloid leukemia, and chronic myelomonocytic leukemia

artículo científico publicado en 2014

Stably integrated and expressed retroviral sequences can influence nuclear location and chromatin condensation of the integration locus ⬇️

artículo científico publicado el 14 de marzo de 2012

The 5q deletion size in myeloid malignancies is correlated to additional chromosomal aberrations and to TP53 mutations

artículo científico publicado en 2016

The clinical and molecular diversity of mast cell leukemia with or without associated hematologic neoplasm

artículo científico publicado en 2017

The mutational landscape of 18 investigated genes clearly separates four subtypes of myelodysplastic/myeloproliferative neoplasms.

artículo científico publicado en 2018

Ultra-deep sequencing leads to earlier and more sensitive detection of the tyrosine kinase inhibitor resistance mutation T315I in chronic myeloid leukemia

artículo científico publicado en 2016

Lista de obras de

A new model for post-integration latency in macroglial cells to study HIV-1 reservoirs of the brain

AML with gain of chromosome 8 as the sole chromosomal abnormality (+8sole) is associated with a specific molecular mutation pattern including ASXL1 mutations in 46.8% of the patients

ASXL2 regulates hematopoiesis in mice and its deficiency promotes myeloid expansion

Application of an NGS-based 28-gene panel in myeloproliferative neoplasms reveals distinct mutation patterns in essential thrombocythaemia, primary myelofibrosis and polycythaemia vera

Comprehensive mutational profiling in advanced systemic mastocytosis

Detection and characterization of homozygosity of mutated by copy neutral loss of heterozygosity in myeloproliferative neoplasms among cases with high mutation loads or with progressive disease

Detection of recurrent and of novel fusion transcripts in myeloid malignancies by targeted RNA sequencing

Dynamics of clonal evolution in myelodysplastic syndromes

Efficacy of azacitidine is independent of molecular and clinical characteristics - an analysis of 128 patients with myelodysplastic syndromes or acute myeloid leukemia and a review of the literature.

Functional nuclear topography of transcriptionally inducible extra-chromosomal transgene clusters

IDH1-R132 changes vary according to NPM1 and other mutations status in AML.

IDH1R132, IDH2R140 and IDH2R172 in AML: different genetic landscapes correlate with outcome and may influence targeted treatment strategies.

Incidence and prognostic impact of cytogenetic aberrations in patients with systemic mastocytosis

Integrating clinical features and genetic lesions in the risk assessment of patients with chronic myelomonocytic leukemia

Karyotype evolution and acquisition of FLT3 or RAS pathway alterations drive progression of myelodysplastic syndrome to acute myeloid leukemia

Molecular analysis of myelodysplastic syndrome with isolated deletion of the long arm of chromosome 5 reveals a specific spectrum of molecular mutations with prognostic impact: a study on 123 patients and 27 genes

Molecular subtypes of NPM1 mutations have different clinical profiles, specific patterns of accompanying molecular mutations and varying outcomes in intermediate risk acute myeloid leukemia

Mutational hierarchies in myelodysplastic syndromes dynamically adapt and evolve upon therapy response and failure

RAS signaling promotes resistance to JAK inhibitors by suppressing BAD-mediated apoptosis

Recurrent CDKN1B (p27) mutations in hairy cell leukemia

Refractory anemia with ring sideroblasts and marked thrombocytosis cases harbor mutations in SF3B1 or other spliceosome genes accompanied by JAK2V617F and ASXL1 mutations

Response and progression on midostaurin in advanced systemic mastocytosis: KIT D816V and other molecular markers

SRSF2 mutations in 275 cases with chronic myelomonocytic leukemia (CMML)

Specific molecular mutation patterns delineate chronic neutrophilic leukemia, atypical chronic myeloid leukemia, and chronic myelomonocytic leukemia

Stably integrated and expressed retroviral sequences can influence nuclear location and chromatin condensation of the integration locus ⬇️

The 5q deletion size in myeloid malignancies is correlated to additional chromosomal aberrations and to TP53 mutations

The clinical and molecular diversity of mast cell leukemia with or without associated hematologic neoplasm

The mutational landscape of 18 investigated genes clearly separates four subtypes of myelodysplastic/myeloproliferative neoplasms.

Ultra-deep sequencing leads to earlier and more sensitive detection of the tyrosine kinase inhibitor resistance mutation T315I in chronic myeloid leukemia

mutated AML can relapse with wild-type : persistent clonal hematopoiesis can drive relapse