Lista de obras -

5-ALA-induced fluorescence behavior of reactive tissue changes following glioblastoma treatment with radiation and chemotherapy

artículo científico publicado en 2014

5-aminolevulinic acid (5-ALA)-induced fluorescence in intracerebral metastases: a retrospective study

artículo científico publicado en 2011

ACTR-05. THE RANDOMIZED PHASE II ARTE TRIAL: BEVACIZUMAB PLUS HYPOFRACTIONATED RADIOTHERAPY VERSUS RADIOTHERAPY ALONE IN ELDERLY PATIENTS WITH NEWLY DIAGNOSED GLIOBLASTOMA.

artículo científico publicado en 2017

Aberrant expression of retinoic acid signaling molecules influences patient survival in astrocytic gliomas

artículo científico publicado en 2011

Adult and pediatric medulloblastomas are genetically distinct and require different algorithms for molecular risk stratification

artículo científico publicado en 2010

Analysing DNA methylation using bisulphite pyrosequencing.

artículo científico publicado en 2011

Anti-O6-methylguanine-methyltransferase (MGMT) immunohistochemistry in glioblastoma multiforme: observer variability and lack of association with patient survival impede its use as clinical biomarker.

artículo científico publicado en 2008

Association of Stem Cell-Related Markers and Survival in Astrocytic Gliomas ⬇️

artículo científico publicado el 1 de marzo de 2011

BCAT1 promotes cell proliferation through amino acid catabolism in gliomas carrying wild-type IDH1.

artículo científico publicado en 2013

CASP9 germline mutation in a family with multiple brain tumors

artículo científico publicado en 2016

Case report: extracranial metastasis from gliosarcoma – the influence of immune system ⬇️

artículo científico publicado el 15 de diciembre de 2010

Cerebellar Hemorrhage in Extremely Low Birth Weight Siblings: Is There a Familial Disposition? ⬇️

artículo científico publicado el 10 de febrero de 2011

Chemotherapy for intracranial ependymoma in adults

artículo científico publicado en 2016

Comparison of (18)F-FET PET and 5-ALA fluorescence in cerebral gliomas

artículo científico publicado en 2010

Cordectomy as final treatment option for diffuse intramedullary malignant glioma using 5-ALA fluorescence-guided resection

artículo científico publicado en 2010

Corrigendum: Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

artículo científico publicado en 2012

DNA hypermethylation and aberrant expression of the EMP3 gene at 19q13.3 in Human Gliomas

artículo científico publicado en 2007

Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing

artículo científico publicado en 2014

Diagnostic performance of 18F-FET PET in newly diagnosed cerebral lesions suggestive of glioma

artículo científico publicado en 2012

Differential retinoic acid signaling in tumors of long- and short-term glioblastoma survivors.

artículo científico publicado en 2011

Dissecting the genomic complexity underlying medulloblastoma

artículo científico publicado en 2012

Efficacy and tolerability of temozolomide in an alternating weekly regimen in patients with recurrent glioma

artículo científico publicado en 2007

Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma

artículo científico publicado en 2014

Epigenetic downregulation of mitogen-activated protein kinase phosphatase MKP-2 relieves its growth suppressive activity in glioma cells

artículo científico publicado en 2010

Epigenetic silencing of the candidate tumor suppressor gene PROX1 in sporadic breast cancer

artículo científico publicado en 2007

Erratum to: Gliomatosis cerebri: no evidence for a separate brain tumor entity

artículo científico publicado en 2016

Expression of nuclear receptor corepressors and class I histone deacetylases in astrocytic gliomas ⬇️

artículo científico publicado el 10 de diciembre de 2010

Finding the anaplastic focus in diffuse gliomas: the value of Gd-DTPA enhanced MRI, FET-PET, and intraoperative, ALA-derived tissue fluorescence

artículo científico publicado en 2011

Frequent epigenetic inactivation of the chaperone SGNE1/7B2 in human gliomas

artículo científico publicado en 2011

Frequent promoter hypermethylation and low expression of the MGMT gene in oligodendroglial tumors.

artículo científico publicado en 2005

Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition

artículo científico publicado en 2014

Genomic and expression profiling of glioblastoma stem cell-like spheroid cultures identifies novel tumor-relevant genes associated with survival

artículo científico publicado en 2009

Giant cell glioblastoma is associated with altered aurora b expression and concomitant p53 mutation

artículo científico publicado en 2010

Gliomatosis cerebri: molecular pathology and clinical course

artículo científico publicado en 2002

Gliomatosis cerebri: no evidence for a separate brain tumor entity

artículo científico publicado en 2015

Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma

artículo científico publicado en 2012

Identification of genomic aberrations associated with shorter overall survival in patients with oligodendroglial tumors

artículo científico publicado en 2007

Inhibition of Wnt/beta-catenin signaling downregulates expression of aldehyde dehydrogenase isoform 3A1 (ALDH3A1) to reduce resistance against temozolomide in glioblastoma in vitro.

artículo científico publicado en 2018

Is it a glioblastoma? In dubio pro 5-ALA!

artículo científico publicado en 2012

LGG-10. PROTEOGENOMICS DISCRIMINATES PEDIATRIC AND ADULT PILOCYTIC ASTROCYTOMA AS DISTINCT BIOLOGICAL ENTITIES.

artículo científico publicado en 2017

Limited role for extended maintenance temozolomide for newly diagnosed glioblastoma

artículo científico publicado en 2017

MGMT Promoter Methylation Is a Strong Prognostic Biomarker for Benefit from Dose-Intensified Temozolomide Rechallenge in Progressive Glioblastoma: The DIRECTOR Trial

artículo científico publicado en 2015

Malignant astrocytomas of elderly patients lack favorable molecular markers: an analysis of the NOA-08 study collective

artículo científico publicado en 2013

Methylation profiling of choroid plexus tumors reveals 3 clinically distinct subgroups

artículo científico publicado en 2016

MiR-328 promotes glioma cell invasion via SFRP1-dependent Wnt-signaling activation

artículo científico publicado en 2013

Molecular Diagnostics of Gliomas Using Next Generation Sequencing of a Glioma-Tailored Gene Panel

artículo científico publicado en 2016

Molecular characterization of long-term survivors of glioblastoma using genome- and transcriptome-wide profiling.

artículo científico publicado en 2014

Molecular classification of diffuse cerebral WHO grade II/III gliomas using genome- and transcriptome-wide profiling improves stratification of prognostically distinct patient groups

artículo científico publicado en 2015

Molecular predictors of progression-free and overall survival in patients with newly diagnosed glioblastoma: a prospective translational study of the German Glioma Network

artículo científico publicado en 2009

Molecular signatures classify astrocytic gliomas by IDH1 mutation status.

artículo científico publicado en 2011

NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomide

artículo científico publicado en 2009

NOA-05 phase 2 trial of procarbazine and lomustine therapy in gliomatosis cerebri

artículo científico publicado en 2011

New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs

artículo científico publicado en 2016

Oligodendroglial tumors: refinement of candidate regions on chromosome arm 1p and correlation of 1p/19q status with survival.

artículo científico publicado en 2004

Optimization of quantitative MGMT promoter methylation analysis using pyrosequencing and combined bisulfite restriction analysis

artículo científico publicado en 2007

Outcome prediction in pediatric medulloblastoma based on DNA copy-number aberrations of chromosomes 6q and 17q and the MYC and MYCN loci

artículo científico publicado en 2009

Patients with IDH1 wild type anaplastic astrocytomas exhibit worse prognosis than IDH1-mutated glioblastomas, and IDH1 mutation status accounts for the unfavorable prognostic effect of higher age: implications for classification of gliomas

artículo científico publicado en 2010

Potential canonical wnt pathway activation in high-grade astrocytomas.

artículo científico publicado en 2012

Predictive impact of MGMT promoter methylation in glioblastoma of the elderly

artículo científico publicado en 2012

Prognostic significance of clinical, histopathological, and molecular characteristics of medulloblastomas in the prospective HIT2000 multicenter clinical trial cohort

artículo científico publicado en 2014

Prognostic significance of molecular markers and extent of resection in primary glioblastoma patients

artículo científico publicado en 2009

Promoter methylation and expression of MGMT and the DNA mismatch repair genes MLH1, MSH2, MSH6 and PMS2 in paired primary and recurrent glioblastomas.

artículo científico publicado en 2011

Proof of principle: supramarginal resection of cerebral metastases in eloquent brain areas

artículo científico publicado en 2012

Prospective cohort study of radiotherapy with concomitant and adjuvant temozolomide chemotherapy for glioblastoma patients with no or minimal residual enhancing tumor load after surgery

artículo científico publicado en 2012

RANK (TNFRSF11A) is epigenetically inactivated and induces apoptosis in gliomas

artículo científico publicado en 2012

Rapid and sensitive assessment of the IDH1 and IDH2 mutation status in cerebral gliomas based on DNA pyrosequencing

artículo científico publicado en 2010

Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma

artículo científico publicado en 2013

Role of LIM and SH3 protein 1 (LASP1) in the metastatic dissemination of medulloblastoma

artículo científico publicado en 2010

Sellar Region Atypical Teratoid/Rhabdoid Tumors (ATRT) in Adults Display DNA Methylation Profiles of the ATRT-MYC Subgroup

artículo científico publicado en 2018

Septic-Metastasizing Aspergillus-Encephalitis Mimicking Massive Cerebral Infarction in a Heart Transplant Recipient: A Case Report

artículo científico publicado en 2014

TRTH-28. HIGH THROUGHPUT SCREENING OF NOVEL HISTONE DEACETYLASE INHIBITORS FOR EPIGENETIC THERAPY OF PRIMARY BRAIN TUMORS.

artículo científico publicado en 2017

Temozolomide chemotherapy alone versus radiotherapy alone for malignant astrocytoma in the elderly: the NOA-08 randomised, phase 3 trial

artículo científico publicado en 2012

The transcription factor evi-1 is overexpressed, promotes proliferation, and is prognostically unfavorable in infratentorial ependymomas

artículo científico publicado en 2011

Troglitazone-mediated sensitization to TRAIL-induced apoptosis is regulated by proteasome-dependent degradation of FLIP and ERK1/2-dependent phosphorylation of BAD.

artículo científico publicado en 2008

Type and frequency of IDH1 and IDH2 mutations are related to astrocytic and oligodendroglial differentiation and age: a study of 1,010 diffuse gliomas.

artículo científico publicado en 2009

Whole-genome paired-end analysis confirms remarkable genomic stability of atypical teratoid/rhabdoid tumors.

artículo científico publicado en 2013

Lista de obras de

5-ALA-induced fluorescence behavior of reactive tissue changes following glioblastoma treatment with radiation and chemotherapy

5-aminolevulinic acid (5-ALA)-induced fluorescence in intracerebral metastases: a retrospective study

ACTR-05. THE RANDOMIZED PHASE II ARTE TRIAL: BEVACIZUMAB PLUS HYPOFRACTIONATED RADIOTHERAPY VERSUS RADIOTHERAPY ALONE IN ELDERLY PATIENTS WITH NEWLY DIAGNOSED GLIOBLASTOMA.

Aberrant expression of retinoic acid signaling molecules influences patient survival in astrocytic gliomas

Adult and pediatric medulloblastomas are genetically distinct and require different algorithms for molecular risk stratification

Analysing DNA methylation using bisulphite pyrosequencing.

Anti-O6-methylguanine-methyltransferase (MGMT) immunohistochemistry in glioblastoma multiforme: observer variability and lack of association with patient survival impede its use as clinical biomarker.

Association of Stem Cell-Related Markers and Survival in Astrocytic Gliomas ⬇️

BCAT1 promotes cell proliferation through amino acid catabolism in gliomas carrying wild-type IDH1.

CASP9 germline mutation in a family with multiple brain tumors

Case report: extracranial metastasis from gliosarcoma – the influence of immune system ⬇️

Cerebellar Hemorrhage in Extremely Low Birth Weight Siblings: Is There a Familial Disposition? ⬇️

Chemotherapy for intracranial ependymoma in adults

Comparison of (18)F-FET PET and 5-ALA fluorescence in cerebral gliomas

Cordectomy as final treatment option for diffuse intramedullary malignant glioma using 5-ALA fluorescence-guided resection

Corrigendum: Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

DNA hypermethylation and aberrant expression of the EMP3 gene at 19q13.3 in Human Gliomas

Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing

Diagnostic performance of 18F-FET PET in newly diagnosed cerebral lesions suggestive of glioma

Differential retinoic acid signaling in tumors of long- and short-term glioblastoma survivors.

Dissecting the genomic complexity underlying medulloblastoma

Efficacy and tolerability of temozolomide in an alternating weekly regimen in patients with recurrent glioma

Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma

Epigenetic downregulation of mitogen-activated protein kinase phosphatase MKP-2 relieves its growth suppressive activity in glioma cells

Epigenetic silencing of the candidate tumor suppressor gene PROX1 in sporadic breast cancer

Erratum to: Gliomatosis cerebri: no evidence for a separate brain tumor entity

Expression of nuclear receptor corepressors and class I histone deacetylases in astrocytic gliomas ⬇️

Finding the anaplastic focus in diffuse gliomas: the value of Gd-DTPA enhanced MRI, FET-PET, and intraoperative, ALA-derived tissue fluorescence

Frequent epigenetic inactivation of the chaperone SGNE1/7B2 in human gliomas

Frequent promoter hypermethylation and low expression of the MGMT gene in oligodendroglial tumors.

Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition

Genomic and expression profiling of glioblastoma stem cell-like spheroid cultures identifies novel tumor-relevant genes associated with survival

Giant cell glioblastoma is associated with altered aurora b expression and concomitant p53 mutation

Gliomatosis cerebri: molecular pathology and clinical course

Gliomatosis cerebri: no evidence for a separate brain tumor entity

Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma

Identification of genomic aberrations associated with shorter overall survival in patients with oligodendroglial tumors

Inhibition of Wnt/beta-catenin signaling downregulates expression of aldehyde dehydrogenase isoform 3A1 (ALDH3A1) to reduce resistance against temozolomide in glioblastoma in vitro.

Is it a glioblastoma? In dubio pro 5-ALA!

LGG-10. PROTEOGENOMICS DISCRIMINATES PEDIATRIC AND ADULT PILOCYTIC ASTROCYTOMA AS DISTINCT BIOLOGICAL ENTITIES.

Limited role for extended maintenance temozolomide for newly diagnosed glioblastoma

MGMT Promoter Methylation Is a Strong Prognostic Biomarker for Benefit from Dose-Intensified Temozolomide Rechallenge in Progressive Glioblastoma: The DIRECTOR Trial

Malignant astrocytomas of elderly patients lack favorable molecular markers: an analysis of the NOA-08 study collective

Methylation profiling of choroid plexus tumors reveals 3 clinically distinct subgroups

MiR-328 promotes glioma cell invasion via SFRP1-dependent Wnt-signaling activation

Molecular Diagnostics of Gliomas Using Next Generation Sequencing of a Glioma-Tailored Gene Panel

Molecular characterization of long-term survivors of glioblastoma using genome- and transcriptome-wide profiling.

Molecular classification of diffuse cerebral WHO grade II/III gliomas using genome- and transcriptome-wide profiling improves stratification of prognostically distinct patient groups

Molecular predictors of progression-free and overall survival in patients with newly diagnosed glioblastoma: a prospective translational study of the German Glioma Network

Molecular signatures classify astrocytic gliomas by IDH1 mutation status.

NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomide

NOA-05 phase 2 trial of procarbazine and lomustine therapy in gliomatosis cerebri

New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs

Oligodendroglial tumors: refinement of candidate regions on chromosome arm 1p and correlation of 1p/19q status with survival.

Optimization of quantitative MGMT promoter methylation analysis using pyrosequencing and combined bisulfite restriction analysis

Outcome prediction in pediatric medulloblastoma based on DNA copy-number aberrations of chromosomes 6q and 17q and the MYC and MYCN loci

Patients with IDH1 wild type anaplastic astrocytomas exhibit worse prognosis than IDH1-mutated glioblastomas, and IDH1 mutation status accounts for the unfavorable prognostic effect of higher age: implications for classification of gliomas

Potential canonical wnt pathway activation in high-grade astrocytomas.

Predictive impact of MGMT promoter methylation in glioblastoma of the elderly

Prognostic significance of clinical, histopathological, and molecular characteristics of medulloblastomas in the prospective HIT2000 multicenter clinical trial cohort

Prognostic significance of molecular markers and extent of resection in primary glioblastoma patients

Promoter methylation and expression of MGMT and the DNA mismatch repair genes MLH1, MSH2, MSH6 and PMS2 in paired primary and recurrent glioblastomas.

Proof of principle: supramarginal resection of cerebral metastases in eloquent brain areas

Prospective cohort study of radiotherapy with concomitant and adjuvant temozolomide chemotherapy for glioblastoma patients with no or minimal residual enhancing tumor load after surgery

RANK (TNFRSF11A) is epigenetically inactivated and induces apoptosis in gliomas

Rapid and sensitive assessment of the IDH1 and IDH2 mutation status in cerebral gliomas based on DNA pyrosequencing

Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma

Role of LIM and SH3 protein 1 (LASP1) in the metastatic dissemination of medulloblastoma

Sellar Region Atypical Teratoid/Rhabdoid Tumors (ATRT) in Adults Display DNA Methylation Profiles of the ATRT-MYC Subgroup

Septic-Metastasizing Aspergillus-Encephalitis Mimicking Massive Cerebral Infarction in a Heart Transplant Recipient: A Case Report

TRTH-28. HIGH THROUGHPUT SCREENING OF NOVEL HISTONE DEACETYLASE INHIBITORS FOR EPIGENETIC THERAPY OF PRIMARY BRAIN TUMORS.

Temozolomide chemotherapy alone versus radiotherapy alone for malignant astrocytoma in the elderly: the NOA-08 randomised, phase 3 trial

The transcription factor evi-1 is overexpressed, promotes proliferation, and is prognostically unfavorable in infratentorial ependymomas

Troglitazone-mediated sensitization to TRAIL-induced apoptosis is regulated by proteasome-dependent degradation of FLIP and ERK1/2-dependent phosphorylation of BAD.

Type and frequency of IDH1 and IDH2 mutations are related to astrocytic and oligodendroglial differentiation and age: a study of 1,010 diffuse gliomas.

Whole-genome paired-end analysis confirms remarkable genomic stability of atypical teratoid/rhabdoid tumors.