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A perspective on re-evaluating digoxin's role in the current management of patients with chronic systolic heart failure: targeting serum concentration to reduce hospitalization and improve safety profile

artículo científico

Acute decompensated heart failure: update on new and emerging evidence and directions for future research

artículo científico publicado en 2013

Acute heart failure: lessons learned, roads ahead

Adherence to guideline-recommended adjunctive heart failure therapies among outpatient cardiology practices (findings from IMPROVE HF).

artículo científico publicado en 2010

Age- and gender-related differences in quality of care and outcomes of patients hospitalized with heart failure (from OPTIMIZE-HF).

artículo científico publicado en 2009

Agents with vasodilator properties in acute heart failure: how to design successful trials

artículo científico publicado en 2015

Anaemia and coronary artery disease severity in patients with heart failure

scientific article published on 18 August 2005

Anemia as a risk factor and therapeutic target in heart failure

artículo científico publicado en 2004

Anemia in patients with heart failure and preserved systolic function

artículo científico publicado en 2006

Antithrombotic outcome trials in acute coronary syndromes: seeking the optimal balance between safety and efficacy

artículo científico publicado en 2013

Assessment of cardiovascular risk of new drugs for the treatment of diabetes mellitus: risk assessment vs. risk aversion

artículo científico publicado en 2016

Association between performance measures and clinical outcomes for patients hospitalized with heart failure

artículo científico publicado en 2007

Cardiac resynchronization therapy utilization for heart failure: findings from IMPROVE HF.

artículo científico publicado en 2009

Cardiopoietic cell therapy for advanced ischaemic heart failure: results at 39 weeks of the prospective, randomized, double blind, sham-controlled CHART-1 clinical trial

artículo científico publicado en 2016

Carvedilol use at discharge in patients hospitalized for heart failure is associated with improved survival: An analysis from Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZE-HF)

article

Characteristics, treatments, and outcomes of patients with preserved systolic function hospitalized for heart failure: a report from the OPTIMIZE-HF Registry

artículo científico publicado en 2007

Characterization and Prognostic Value of Persistent Hyponatremia in Patients With Severe Heart Failure in the ESCAPE Trial

article

Clinical outcome endpoints in heart failure trials: a European Society of Cardiology Heart Failure Association consensus document

artículo científico publicado en 2013

Clinical outcomes in patients on beta-blocker therapy admitted with worsening chronic heart failure

artículo científico publicado en 2003

Continuous versus bolus dosing of Furosemide for patients hospitalized for heart failure

scientific article published on 27 April 2010

Current challenges for clinical trials of cardiovascular medical devices

artículo científico

Day of admission and clinical outcomes for patients hospitalized for heart failure: findings from the Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients With Heart Failure (OPTIMIZE-HF).

artículo científico publicado en 2008

Demographics, clinical characteristics, and outcomes of patients hospitalized for decompensated heart failure: observations from the IMPACT-HF registry

artículo científico publicado en 2005

Depression and Clinical Outcomes in Heart Failure: An OPTIMIZE-HF Analysis

article

Design considerations and proposed template for clinical trials in hospitalized patients with decompensated chronic heart failure

artículo científico publicado en 2003

Design considerations for clinical trials of autonomic modulation therapies targeting hypertension and heart failure

artículo científico publicado en 2014

Designing phase 3 sepsis trials: application of learned experiences from critical care trials in acute heart failure

artículo científico publicado en 2016

Diabetes clinical trials: helped or hindered by the current shift in regulatory requirements?

artículo científico publicado en 2012

Dosing of beta-blocker therapy before, during, and after hospitalization for heart failure (from Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure).

artículo científico publicado en 2008

Early diagnosis of acute coronary syndrome

artículo científico publicado en 2017

Effect of angiotensin-converting enzyme inhibitors, beta blockers, statins, and aspirin on C-reactive protein levels in outpatients with heart failure

artículo científico publicado en 2004

Electronic health records and quality of care for heart failure

artículo científico publicado en 2010

Electronic health records to facilitate clinical research

artículo científico publicado en 2016

Emergency management of severe hyperkalemia: Guideline for best practice and opportunities for the future

artículo científico publicado en 2016

End-of-life care in patients with heart failure

artículo científico publicado en 2014

Erratum to "Traditional and new composite endpoints in heart failure clinical trials: facilitating comprehensive efficacy assessments and improving trial efficiency" [Eur J Heart Fail 2016;18:482-489].

artículo científico publicado en 2016

Evidence of clinical practice heterogeneity in the use of implantable cardioverter-defibrillators in heart failure and post–myocardial infarction left ventricular dysfunction: Findings from IMPROVE HF

article

Evolution of natriuretic peptide biomarkers in heart failure: Implications for clinical care and clinical trials

artículo científico publicado en 2018

Factors identified as precipitating hospital admissions for heart failure and clinical outcomes: findings from OPTIMIZE-HF.

artículo científico publicado en 2008

Galectin-3 in patients with heart failure with preserved ejection fraction: results from the Aldo-DHF trial

artículo científico publicado en 2014

Globalization of cardiovascular clinical research: the balance between meeting medical needs and maintaining scientific standards

artículo científico

Heart Failure in Non-Caucasians, Women, and Older Adults: A White Paper on Special Populations From the Heart Failure Society of America Guideline Committee

artículo científico publicado en 2015

Heart failure as an endpoint in heart failure and non-heart failure cardiovascular clinical trials: the need for a consensus definition

artículo científico publicado en 2008

Heart failure care in the outpatient cardiology practice setting: findings from IMPROVE HF.

artículo científico publicado en 2008

Improvement in hyponatremia during hospitalization for worsening heart failure is associated with improved outcomes: insights from the Acute and Chronic Therapeutic Impact of a Vasopressin Antagonist in Chronic Heart Failure (ACTIV in CHF) trial

article

Improving evidence-based care for heart failure in outpatient cardiology practices: primary results of the Registry to Improve the Use of Evidence-Based Heart Failure Therapies in the Outpatient Setting (IMPROVE HF).

artículo científico publicado en 2010

Improving public health by improving clinical trial guidelines and their application

artículo científico publicado en 2017

Improving the Use of Evidence-Based Heart Failure Therapies in the Outpatient Setting: The IMPROVE HF performance improvement registry

article

Independent academic Data Monitoring Committees for clinical trials in cardiovascular and cardiometabolic diseases

artículo científico publicado en 2017

Indications for cardiac resynchronization therapy: 2011 update from the Heart Failure Society of America Guideline Committee

artículo científico publicado en 2012

Influence of a performance-improvement initiative on quality of care for patients hospitalized with heart failure: results of the Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients With Heart Failure (OPTIMIZE-HF).

artículo científico

Influence of beta-blocker continuation or withdrawal on outcomes in patients hospitalized with heart failure: findings from the OPTIMIZE-HF program

artículo científico publicado en 2008

Influence of coronary angiography on the utilization of therapies in patients with acute heart failure syndromes: findings from Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZE-HF).

artículo científico publicado en 2009

Influence of coronary artery disease and coronary revascularization status on outcomes in patients with acute heart failure syndromes: A report from OPTIMIZE-HF (Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart F

article

Influence of dedicated heart failure clinics on delivery of recommended therapies in outpatient cardiology practices: findings from the Registry to Improve the Use of Evidence-Based Heart Failure Therapies in the Outpatient Setting (IMPROVE HF).

artículo científico publicado en 2010

Influence of diabetes on characteristics and outcomes in patients hospitalized with heart failure: A report from the Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZE-HF)

article

Influence of diabetes on characteristics and outcomes in patients hospitalized with heart failure: a report from the Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZE-HF).

artículo científico publicado en 2007

Influence of patient age and sex on delivery of guideline-recommended heart failure care in the outpatient cardiology practice setting: findings from IMPROVE HF.

artículo científico publicado en 2009

Influence of renal function on the use of guideline-recommended therapies for patients with heart failure

artículo científico publicado en 2010

Insights from the early experience of the Society of Thoracic Surgeons/American College of Cardiology Transcatheter Valve Therapy Registry

artículo científico publicado en 2015

Is thrombosis a contributor to heart failure pathophysiology? Possible mechanisms, therapeutic opportunities, and clinical investigation challenges

artículo científico publicado en 2013

Lower serum sodium is associated with increased short-term mortality in hospitalized patients with worsening heart failure: results from the Outcomes of a Prospective Trial of Intravenous Milrinone for Exacerbations of Chronic Heart Failure (OPTIME-

artículo científico publicado en 2005

Mineralocorticoid receptor antagonists for heart failure with reduced ejection fraction: integrating evidence into clinical practice

artículo científico publicado en 2012

New Strategies for the Development of Lipid Lowering Therapies to Reduce Cardiovascular Risk

artículo científico publicado en 2017

New approaches to hyperkalemia in patients with indications for renin angiotensin aldosterone inhibitors: Considerations for trial design and regulatory approval

artículo científico publicado en 2016

New medicinal products for chronic heart failure: advances in clinical trial design and efficacy assessment

artículo científico publicado en 2017

New strategies for heart failure with preserved ejection fraction: the importance of targeted therapies for heart failure phenotypes

artículo científico publicado en 2014

Outpatient cardiology practices with advanced practice nurses and physician assistants provide similar delivery of recommended therapies (findings from IMPROVE HF).

artículo científico publicado en 2010

Overview of current noninodilator therapies for acute heart failure syndromes

artículo científico publicado en 2005

Predictors of Delivery of Hospital-Based Heart Failure Patient Education: A Report from OPTIMIZE-HF

article

Predictors of in-hospital mortality in patients hospitalized for heart failure: insights from the Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZE-HF).

artículo científico publicado en 2008

Predictors of mortality after discharge in patients hospitalized with heart failure: an analysis from the Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZE-HF).

artículo científico publicado en 2008

Prognostic Value of Blood Urea Nitrogen in Patients Hospitalized With Worsening Heart Failure: Insights From the Acute and Chronic Therapeutic Impact of a Vasopressin Antagonist in Chronic Heart Failure (ACTIV in CHF) Study

article

Prospective evaluation of beta-blocker use at the time of hospital discharge as a heart failure performance measure: results from OPTIMIZE-HF.

artículo científico publicado en 2007

Prospective evaluation of the association between hemoglobin concentration and quality of life in patients with heart failure

artículo científico publicado en 2009

Quality of care of and outcomes for African Americans hospitalized with heart failure: findings from the OPTIMIZE-HF (Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients With Heart Failure) registry

artículo científico publicado en 2008

Relation between dose of loop diuretics and outcomes in a heart failure population: results of the ESCAPE trial

artículo científico publicado en 2007

Relation of low hemoglobin and anemia to morbidity and mortality in patients hospitalized with heart failure (insight from the OPTIMIZE-HF registry).

artículo científico publicado en 2008

Report of the European Society of Cardiology Cardiovascular Round Table regulatory workshop update of the evaluation of new agents for the treatment of acute coronary syndrome: Executive summary

article by Héctor Bueno et al published 29 June 2016 in European heart journal. Acute cardiovascular care

Role of Payers in the Development of Cardiovascular Therapeutics: Misalignment Between Approval and Reimbursement

artículo científico publicado en 2017

Safety and efficacy of sertraline for depression in patients with heart failure: results of the SADHART-CHF (Sertraline Against Depression and Heart Disease in Chronic Heart Failure) trial

artículo científico publicado en 2010

Statement regarding the pre and post market assessment of durable, implantable ventricular assist devices in the United States

artículo científico publicado en 2012

Statement regarding the pre and post market assessment of durable, implantable ventricular assist devices in the United States: executive summary

artículo científico publicado en 2012

Streamlining cardiovascular clinical trials to improve efficiency and generalisability

artículo científico publicado en 2017

Surrogate end points in heart failure trials

artículo científico publicado en 2003

Systolic blood pressure at admission, clinical characteristics, and outcomes in patients hospitalized with acute heart failure

artículo científico publicado en 2006

Tezosentan in patients with acute heart failure and acute coronary syndromes: results of the Randomized Intravenous TeZosentan Study (RITZ-4).

artículo científico publicado en 2003

The Pilot Randomized Study of Nesiritide Versus Dobutamine in Heart Failure (PRESERVD-HF).

artículo científico publicado en 2005

Traditional and new composite endpoints in heart failure clinical trials: facilitating comprehensive efficacy assessments and improving trial efficiency

artículo científico publicado en 2016

Trials of implantable monitoring devices in heart failure: which design is optimal?

artículo científico publicado en 2014

Underutilization of evidence-based therapies in heart failure: the pharmacist's role

artículo científico publicado en 2007

Update on Aldosterone Antagonists Use in Heart Failure With Reduced Left Ventricular Ejection Fraction Heart Failure Society of America Guidelines Committee

artículo científico publicado en 2012

Usefulness of anemia as a predictor of death and rehospitalization in patients with decompensated heart failure

artículo científico publicado en 2003

When to stop a clinical trial early for benefit: lessons learned and future approaches

artículo científico

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