Lista de obras - Gunilla Westergren-Thorsson

2DDB - a bioinformatics solution for analysis of quantitative proteomics data

artículo científico publicado en 2006

5-HT2B receptor antagonists attenuate myofibroblast differentiation and subsequent fibrotic responses in vitro and in vivo

artículo científico

A proteomic approach to mimic fibrosis disease evolvement by an in vitro cell line

artículo científico publicado en 2001

Aberrant nonfibrotic parenchyma in idiopathic pulmonary fibrosis is correlated with decreased β-catenin inhibition and increased Wnt5a/b interaction

artículo científico publicado en 2016

Absence of fibromodulin affects matrix composition, collagen deposition and cell turnover in healthy and fibrotic lung parenchyma

artículo científico publicado en 2014

Activated MCTC mast cells infiltrate diseased lung areas in cystic fibrosis and idiopathic pulmonary fibrosis

artículo científico publicado en 2011

Activation of platelet-derived growth factor pathway in human asthmatic pulmonary-derived mesenchymal cells

artículo científico publicado en 2003

Acute lung injury in acute pancreatitis – Awaiting the big leap ⬇️

artículo científico publicado el 29 de junio de 2012

Altered expression of small proteoglycans, collagen, and transforming growth factor-beta 1 in developing bleomycin-induced pulmonary fibrosis in rats.

artículo científico publicado en 1993

Altered fibroblast proteoglycan production in COPD.

artículo científico publicado en 2010

Antiproliferative Heparan Sulfate Inhibiting Hyaluronan and Transforming Growth Factor-β Expression in Human Lung Fibroblast Cells: A Possible Antifibrotic Therapy?

Biglycan and decorin induce morphological and cytoskeletal changes involving signalling by the small GTPases RhoA and Rac1 resulting in lung fibroblast migration

artículo científico publicado en 2003

Biglycan isoforms with differences in polysaccharide substitution and core protein in human lung fibroblasts

artículo científico publicado en 2002

Binding, internalization, and degradation of antiproliferative heparan sulfate by human embryonic lung fibroblasts

scientific article published on 01 March 1997

Biomarkers from bronchoalveolar lavage fluid in systemic sclerosis patients with interstitial lung disease relate to severity of lung fibrosis.

artículo científico publicado en 2013

Bronchial extracellular matrix from COPD patients induces altered gene expression in repopulated primary human bronchial epithelial cells

artículo científico publicado en 2018

Budesonide/formoterol effects on metalloproteolytic balance in TGFbeta-activated human lung fibroblasts

artículo científico publicado en 2009

Changes in paraurethral connective tissue at menopause are counteracted by estrogen.

artículo científico publicado en 1996

Concise Review: The Bystander Effect: Mesenchymal Stem Cell-Mediated Lung Repair

artículo científico publicado en 2016

Controlled and uncontrolled asthma display distinct alveolar tissue matrix compositions

artículo científico publicado en 2014

Correlation between airway responsiveness and proteoglycan production by bronchial fibroblasts from normal and asthmatic subjects

artículo científico publicado en 2002

Crosstalk between Mast Cells and Lung Fibroblasts Is Modified by Alveolar Extracellular Matrix and Influences Epithelial Migration

artículo científico publicado en 2021

Cytokine regulation of proteoglycan production in fibroblasts: separate and synergistic effects

artículo científico publicado en 1997

Defective alterations in the collagen network to prostacyclin in COPD lung fibroblasts ⬇️

artículo científico publicado el 14 de febrero de 2013

Differential expressions of mRNA for proteoglycans, collagens and transforming growth factor-beta in the human cervix during pregnancy and involution.

artículo científico publicado en 1998

Disubstituted naphthyl β-D-xylopyranosides: Synthesis, GAG priming, and histone acetyltransferase (HAT) inhibition

artículo científico publicado en 2016

Early extracellular matrix changes are associated with later development of bronchiolitis obliterans syndrome after lung transplantation

artículo científico publicado en 2017

Effects of 5-HT2 receptor antagonists on bronchoconstriction and pulmonary remodeling processes

artículo científico publicado en 2018

Endoplasmic reticulum, Golgi, and lysosomes are disorganized in lung fibroblasts from chronic obstructive pulmonary disease patients

artículo científico publicado en 2018

Enhanced ROCK1 dependent contractility in fibroblast from chronic obstructive pulmonary disease patients

artículo científico publicado en 2012

Epithelial G protein-coupled receptor kinases regulate the initial inflammatory response during mycobacterial infection ⬇️

artículo científico publicado el 28 de noviembre de 2012

Exploration of the active site of β4GalT7: modifications of the aglycon of aromatic xylosides

artículo científico publicado en 2015

Expression, activity and localization of lysosomal sulfatases in Chronic Obstructive Pulmonary Disease

artículo científico publicado en 2019

Extracellular matrix alterations and acute inflammation; developing in parallel during early induction of pulmonary fibrosis ⬇️

artículo científico publicado el 2 de abril de 2012

Fibrocytes and the tissue niche in lung repair ⬇️

artículo científico publicado el 9 de junio de 2011

Fibrocytes are associated with vascular and parenchymal remodelling in patients with obliterative bronchiolitis

artículo científico publicado en 2009

Functional and phenotypical comparison of myofibroblasts derived from biopsies and bronchoalveolar lavage in mild asthma and scleroderma

artículo científico publicado en 2006

Haemophilus influenzae P4 Interacts With Extracellular Matrix Proteins Promoting Adhesion and Serum Resistance

artículo científico publicado en 2015

Heparan/chondroitin/dermatan sulfate primer 2-(6-hydroxynaphthyl)-O-beta-D-xylopyranoside preferentially inhibits growth of transformed cells.

artículo científico publicado en 1998

Human cervical ripening, an inflammatory process mediated by cytokines

scientific article published on 01 April 2000

Increased deposition of glycosaminoglycans and altered structure of heparan sulfate in idiopathic pulmonary fibrosis

artículo científico publicado en 2016

Innate Immune Responses after Airway Epithelial Stimulation with Mycobacterium bovis Bacille-Calmette Guérin

artículo científico publicado en 2016

Interleukin-15 attenuates transforming growth factor-β1-induced myofibroblast differentiation in human fetal lung fibroblasts

artículo científico publicado el 24 de agosto de 2010

L-iduronate-rich glycosaminoglycans inhibit growth of normal fibroblasts independently of serum or added growth factors

artículo científico publicado en 1993

Limited impact of fibromodulin deficiency on the development of experimental skin fibrosis

artículo científico publicado en 2016

Lung fibroblast clones from normal and fibrotic subjects differ in hyaluronan and decorin production and rate of proliferation

artículo científico publicado en 2004

Lung fibroblast proteoglycan production induced by serum is inhibited by budesonide and formoterol

artículo científico publicado en 2005

MSC from fetal and adult lungs possess lung-specific properties compared to bone marrow-derived MSC

artículo científico publicado en 2016

Mast cells and mast cell tryptase enhance migration of human lung fibroblasts through protease-activated receptor 2

scholarly article by Mariam Bagher published in September 2018

Mycobacteria Manipulate G-Protein-Coupled Receptors to Increase Mucosal Rac1 Expression in the Lungs

artículo científico publicado en 2016

Mycobacteria bypass mucosal NF-kB signalling to induce an epithelial anti-inflammatory IL-22 and IL-10 response

artículo científico publicado en 2014

Mycobacterium bovis bacilli Calmette-Guerin regulates leukocyte recruitment by modulating alveolar inflammatory responses ⬇️

artículo científico publicado el 4 de noviembre de 2011

Myofibroblast accumulation correlates with the formation of fibrotic tissue in a rat air pouch model.

artículo científico publicado en 2002

Nanocapillary liquid chromatography interfaced to tandem matrix-assisted laser desorption/ionization and electrospray ionization-mass spectrometry: mapping the nuclear proteome of human fibroblasts

artículo científico publicado en 2003

Nontypeable Haemophilus influenzae adhesin protein E: characterization and biological activity

artículo científico publicado en 2009

Pathological airway remodelling in inflammation

artículo científico publicado en 2010

Proliferation of cultured fibroblasts is inhibited by L-iduronate-containing glycosaminoglycans

scientific article published on 01 June 1991

Proteoglycan and proteome profiling of central human pulmonary fibrotic tissue utilizing miniaturized sample preparation: a feasibility study

artículo científico publicado en 2002

Proteoglycan production in disomic and trisomy 7-carrying human synovial cells.

artículo científico publicado en 2002

Proteome annotations and identifications of the human pulmonary fibroblast

artículo científico publicado en 2004

Proteomic 2DE database for spot selection, automated annotation, and data analysis

artículo científico publicado en 2002

Proteomics -- the protein expression technology to study connective tissue biology.

artículo científico publicado en 2001

Pulmonary fibrosis in vivo displays increased p21 expression reduced by 5-HT2B receptor antagonists in vitro - a potential pathway affecting proliferation

artículo científico publicado en 2018

Pulmonary vascular changes in asthma and COPD.

artículo científico publicado en 2014

Quantifying extracellular matrix turnover in human lung scaffold cultures

artículo científico publicado en 2018

Quantitative proteomic analysis of fibroblast nuclear proteins after stimulation with mitogen activated protein kinase inhibiting heparan sulfate

artículo científico publicado en 2005

Quantitative proteomic characterization of lung-MSC and bone marrow-MSC using DIA-mass spectrometry

artículo científico

Quantitative proteomic characterization of the lung extracellular matrix in chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis

artículo científico publicado en 2018

Regulation of the chondroitin/dermatan fine structure by transforming growth factor-beta1 through effects on polymer-modifying enzymes

artículo científico publicado en 2005

Relationship between matrix production by bronchial fibroblasts and lung function and AHR in asthma

artículo científico publicado en 2010

Specific haptoglobin expression in bronchoalveolar lavage during differentiation of circulating fibroblast progenitor cells in mild asthma

artículo científico publicado en 2006

Specific subsets of mesenchymal stroma cells to treat lung disorders--finding the Holy Grail

artículo científico publicado en 2014

Splicosomal and serine and arginine-rich splicing factors as targets for TGF-β.

artículo científico publicado en 2012

TGF-beta enhances the production of hyaluronan in human lung but not in skin fibroblasts

artículo científico publicado en 1990

TGFβ-induced matrix production by bronchial fibroblasts in asthma: Budesonide and formoterol effects ⬇️

artículo científico publicado el 21 de abril de 2011

The Pulmonary Extracellular Matrix Is a Bactericidal Barrier Against in Chronic Obstructive Pulmonary Disease (COPD): Implications for an Innate Host Defense Function of Collagen VI

scholarly article by Suado M Abdillahi et al published 2018 in Frontiers in Immunology

The Respiratory Pathogen Moraxella catarrhalis Targets Collagen for Maximal Adherence to Host Tissues

artículo científico publicado en 2016

The extracellular matrix - the under-recognized element in lung disease?

artículo científico publicado en 2016

The importance of fibroblasts in remodelling of the human uterine cervix during pregnancy and parturition

artículo científico publicado en 2007

The synthesis of a family of structurally related proteoglycans in fibroblasts is differently regulated by TFG-beta

artículo científico publicado en 1991

Tissue fibrocytes in patients with mild asthma: a possible link to thickness of reticular basement membrane?

artículo científico publicado en 2006

Transforming growth factor-beta induces selective increase of proteoglycan production and changes in the copolymeric structure of dermatan sulphate in human skin fibroblasts

scientific article published on 01 April 1992

Tumour necrosis factor-alpha interacts with biglycan and decorin

artículo científico publicado en 2002

Uncontrolled Asthmatics Have Increased FceRI+ and TGF-β Positive MCTC Mast Cells and Collagen VI in the Alveolar Parenchyma

artículo científico publicado en 2018

VEGF synthesis is induced by prostacyclin and TGF-β in distal lung fibroblasts from COPD patients and control subjects: Implications for pulmonary vascular remodelling

artículo científico publicado en 2017

Versican accumulates in vascular lesions in pulmonary arterial hypertension

artículo científico publicado en 2016

Versican in inflammation and tissue remodeling: the impact on lung disorders

artículo científico publicado en 2015

Viral Stimuli Trigger Exaggerated Thymic Stromal Lymphopoietin Expression by Chronic Obstructive Pulmonary Disease Epithelium: Role of Endosomal TLR3 and Cytosolic RIG-I-Like Helicases ⬇️

artículo científico publicado el 20 de junio de 2011

iNOS affects matrix production in distal lung fibroblasts from patients with mild asthma

artículo científico publicado en 2015

Lista de obras de Gunilla Westergren-Thorsson

2DDB - a bioinformatics solution for analysis of quantitative proteomics data

5-HT2B receptor antagonists attenuate myofibroblast differentiation and subsequent fibrotic responses in vitro and in vivo

A proteomic approach to mimic fibrosis disease evolvement by an in vitro cell line

Aberrant nonfibrotic parenchyma in idiopathic pulmonary fibrosis is correlated with decreased β-catenin inhibition and increased Wnt5a/b interaction

Absence of fibromodulin affects matrix composition, collagen deposition and cell turnover in healthy and fibrotic lung parenchyma

Activated MCTC mast cells infiltrate diseased lung areas in cystic fibrosis and idiopathic pulmonary fibrosis

Activation of platelet-derived growth factor pathway in human asthmatic pulmonary-derived mesenchymal cells

Acute lung injury in acute pancreatitis – Awaiting the big leap ⬇️

Altered expression of small proteoglycans, collagen, and transforming growth factor-beta 1 in developing bleomycin-induced pulmonary fibrosis in rats.

Altered fibroblast proteoglycan production in COPD.

Antiproliferative Heparan Sulfate Inhibiting Hyaluronan and Transforming Growth Factor-β Expression in Human Lung Fibroblast Cells: A Possible Antifibrotic Therapy?

Biglycan and decorin induce morphological and cytoskeletal changes involving signalling by the small GTPases RhoA and Rac1 resulting in lung fibroblast migration

Biglycan isoforms with differences in polysaccharide substitution and core protein in human lung fibroblasts

Binding, internalization, and degradation of antiproliferative heparan sulfate by human embryonic lung fibroblasts

Biomarkers from bronchoalveolar lavage fluid in systemic sclerosis patients with interstitial lung disease relate to severity of lung fibrosis.

Bronchial extracellular matrix from COPD patients induces altered gene expression in repopulated primary human bronchial epithelial cells

Budesonide/formoterol effects on metalloproteolytic balance in TGFbeta-activated human lung fibroblasts

Changes in paraurethral connective tissue at menopause are counteracted by estrogen.

Concise Review: The Bystander Effect: Mesenchymal Stem Cell-Mediated Lung Repair

Controlled and uncontrolled asthma display distinct alveolar tissue matrix compositions

Correlation between airway responsiveness and proteoglycan production by bronchial fibroblasts from normal and asthmatic subjects

Crosstalk between Mast Cells and Lung Fibroblasts Is Modified by Alveolar Extracellular Matrix and Influences Epithelial Migration

Cytokine regulation of proteoglycan production in fibroblasts: separate and synergistic effects

Defective alterations in the collagen network to prostacyclin in COPD lung fibroblasts ⬇️

Differential expressions of mRNA for proteoglycans, collagens and transforming growth factor-beta in the human cervix during pregnancy and involution.

Disubstituted naphthyl β-D-xylopyranosides: Synthesis, GAG priming, and histone acetyltransferase (HAT) inhibition

Early extracellular matrix changes are associated with later development of bronchiolitis obliterans syndrome after lung transplantation

Effects of 5-HT2 receptor antagonists on bronchoconstriction and pulmonary remodeling processes

Endoplasmic reticulum, Golgi, and lysosomes are disorganized in lung fibroblasts from chronic obstructive pulmonary disease patients

Enhanced ROCK1 dependent contractility in fibroblast from chronic obstructive pulmonary disease patients

Epithelial G protein-coupled receptor kinases regulate the initial inflammatory response during mycobacterial infection ⬇️

Exploration of the active site of β4GalT7: modifications of the aglycon of aromatic xylosides

Expression, activity and localization of lysosomal sulfatases in Chronic Obstructive Pulmonary Disease

Extracellular matrix alterations and acute inflammation; developing in parallel during early induction of pulmonary fibrosis ⬇️

Fibrocytes and the tissue niche in lung repair ⬇️

Fibrocytes are associated with vascular and parenchymal remodelling in patients with obliterative bronchiolitis

Functional and phenotypical comparison of myofibroblasts derived from biopsies and bronchoalveolar lavage in mild asthma and scleroderma

Haemophilus influenzae P4 Interacts With Extracellular Matrix Proteins Promoting Adhesion and Serum Resistance

Heparan/chondroitin/dermatan sulfate primer 2-(6-hydroxynaphthyl)-O-beta-D-xylopyranoside preferentially inhibits growth of transformed cells.

Human cervical ripening, an inflammatory process mediated by cytokines

Increased deposition of glycosaminoglycans and altered structure of heparan sulfate in idiopathic pulmonary fibrosis

Innate Immune Responses after Airway Epithelial Stimulation with Mycobacterium bovis Bacille-Calmette Guérin

Interleukin-15 attenuates transforming growth factor-β1-induced myofibroblast differentiation in human fetal lung fibroblasts

L-iduronate-rich glycosaminoglycans inhibit growth of normal fibroblasts independently of serum or added growth factors

Limited impact of fibromodulin deficiency on the development of experimental skin fibrosis

Lung fibroblast clones from normal and fibrotic subjects differ in hyaluronan and decorin production and rate of proliferation

Lung fibroblast proteoglycan production induced by serum is inhibited by budesonide and formoterol

MSC from fetal and adult lungs possess lung-specific properties compared to bone marrow-derived MSC

Mast cells and mast cell tryptase enhance migration of human lung fibroblasts through protease-activated receptor 2

Mycobacteria Manipulate G-Protein-Coupled Receptors to Increase Mucosal Rac1 Expression in the Lungs

Mycobacteria bypass mucosal NF-kB signalling to induce an epithelial anti-inflammatory IL-22 and IL-10 response

Mycobacterium bovis bacilli Calmette-Guerin regulates leukocyte recruitment by modulating alveolar inflammatory responses ⬇️

Myofibroblast accumulation correlates with the formation of fibrotic tissue in a rat air pouch model.

Nanocapillary liquid chromatography interfaced to tandem matrix-assisted laser desorption/ionization and electrospray ionization-mass spectrometry: mapping the nuclear proteome of human fibroblasts

Nontypeable Haemophilus influenzae adhesin protein E: characterization and biological activity

Pathological airway remodelling in inflammation

Proliferation of cultured fibroblasts is inhibited by L-iduronate-containing glycosaminoglycans

Proteoglycan and proteome profiling of central human pulmonary fibrotic tissue utilizing miniaturized sample preparation: a feasibility study

Proteoglycan production in disomic and trisomy 7-carrying human synovial cells.

Proteome annotations and identifications of the human pulmonary fibroblast

Proteomic 2DE database for spot selection, automated annotation, and data analysis

Proteomics -- the protein expression technology to study connective tissue biology.

Pulmonary fibrosis in vivo displays increased p21 expression reduced by 5-HT2B receptor antagonists in vitro - a potential pathway affecting proliferation

Pulmonary vascular changes in asthma and COPD.

Quantifying extracellular matrix turnover in human lung scaffold cultures

Quantitative proteomic analysis of fibroblast nuclear proteins after stimulation with mitogen activated protein kinase inhibiting heparan sulfate

Quantitative proteomic characterization of lung-MSC and bone marrow-MSC using DIA-mass spectrometry

Quantitative proteomic characterization of the lung extracellular matrix in chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis

Regulation of the chondroitin/dermatan fine structure by transforming growth factor-beta1 through effects on polymer-modifying enzymes

Relationship between matrix production by bronchial fibroblasts and lung function and AHR in asthma

Specific haptoglobin expression in bronchoalveolar lavage during differentiation of circulating fibroblast progenitor cells in mild asthma

Specific subsets of mesenchymal stroma cells to treat lung disorders--finding the Holy Grail

Splicosomal and serine and arginine-rich splicing factors as targets for TGF-β.

TGF-beta enhances the production of hyaluronan in human lung but not in skin fibroblasts

TGFβ-induced matrix production by bronchial fibroblasts in asthma: Budesonide and formoterol effects ⬇️

The Pulmonary Extracellular Matrix Is a Bactericidal Barrier Against in Chronic Obstructive Pulmonary Disease (COPD): Implications for an Innate Host Defense Function of Collagen VI

The Respiratory Pathogen Moraxella catarrhalis Targets Collagen for Maximal Adherence to Host Tissues

The extracellular matrix - the under-recognized element in lung disease?

The importance of fibroblasts in remodelling of the human uterine cervix during pregnancy and parturition