Lista de obras - Millie M. Georgiadis - Dominio Público Uruguay

"Skinny" and "Fat" DNA: Two New Double Helices

scientific article published on 10 September 2018

A high-throughput, high-resolution strategy for the study of site-selective DNA binding agents: analysis of a "highly twisted" benzimidazole-diamidine

artículo científico publicado en 2006

A host-guest approach for determining drug-DNA interactions: an example using netropsin

artículo científico publicado en 2005

APE1/Ref-1 role in redox signaling: translational applications of targeting the redox function of the DNA repair/redox protein APE1/Ref-1.

artículo científico publicado en 2012

Base excision repair apurinic/apyrimidinic endonucleases in apicomplexan parasite Toxoplasma gondii ⬇️

artículo científico publicado el 24 de febrero de 2011

Biochemical characterization of a SET and transposase fusion protein, Metnase: its DNA binding and DNA cleavage activity

artículo científico publicado en 2007

Building better DNA polymerases: Engineering the replication of expanded genetic alphabets

artículo científico publicado en 2020

Building better enzymes: Molecular basis of improved non-natural nucleobase incorporation by an evolved DNA polymerase

artículo científico publicado en 2019

Characterization of critical interactions between Ndt80 and MSE DNA defining a novel family of Ig-fold transcription factors

artículo científico publicado en 2004

Characterization of the Redox Activity and Disulfide Bond Formation in Apurinic/Apyrimidinic Endonuclease ⬇️

artículo científico publicado el 4 de enero de 2012

Consecutive non-natural PZ nucleobase pairs in DNA impact helical structure as seen in 50 μs molecular dynamics simulations

artículo científico publicado en 2017

Crystal Structure of a Trypanocidal 4,4′-Bis(imidazolinylamino)diphenylamine Bound to DNA ,

artículo científico publicado en 2009

Crystal Structures of GCN2 Protein Kinase C-terminal Domains Suggest Regulatory Differences in Yeast and Mammals

artículo científico publicado en 2014

Crystal structure of DNA-bound Co(III)·bleomycin B2: Insights on intercalation and minor groove binding

artículo científico publicado en 2008

Crystal structure of the DNA-binding domain from Ndt80, a transcriptional activator required for meiosis in yeast

artículo científico publicado en 2002

Crystal structure of the human Hsmar1-derived transposase domain in the DNA repair enzyme Metnase

artículo científico publicado en 2010

Crystal structures of oligonucleotides including the integrase processing site of the Moloney murine leukemia virus

artículo científico publicado en 2006

Crystallization of and selenomethionine phasing strategy for a SETMAR-DNA complex

artículo científico publicado en 2016

Crystallographic studies of a novel DNA-binding domain from the yeast transcriptional activator Ndt80

artículo científico publicado en 2002

Differential multimerization of Moloney murine leukemia virus integrase purified under nondenaturing conditions.

artículo científico publicado en 2003

Discovery of Macrocyclic Inhibitors of Apurinic/Apyrimidinic Endonuclease 1

scientific article published on 06 February 2019

Fragment- and structure-based drug discovery for developing therapeutic agents targeting the DNA Damage Response

artículo científico publicado en 2020

Functional Analysis of Novel Analogues of E3330 That Block the Redox Signaling Activity of the Multifunctional AP Endonuclease/Redox Signaling Enzyme APE1/Ref-1 ⬇️

artículo científico publicado el 4 de enero de 2011

Hachimoji DNA and RNA: A genetic system with eight building blocks

artículo científico publicado en 2019

High-resolution crystal structures reveal plasticity in the metal binding site of apurinic/apyrimidinic endonuclease I.

artículo científico publicado en 2014

Inhibition of apurinic/apyrimidinic endonuclease I's redox activity revisited

artículo científico publicado en 2013

Interactions of apurinic/apyrimidinic endonuclease with a redox inhibitor: evidence for an alternate conformation of the enzyme

artículo científico publicado en 2010

Novel small-molecule inhibitor of apurinic/apyrimidinic endonuclease 1 blocks proliferation and reduces viability of glioblastoma cells

artículo científico publicado en 2010

Phosphorylation of SIMPL modulates RelA-associated NF-kappaB-dependent transcription

artículo científico publicado en 2006

Redox regulation of DNA repair: implications for human health and cancer therapeutic development

artículo científico publicado en 2010

Role of the multifunctional DNA repair and redox signaling protein Ape1/Ref-1 in cancer and endothelial cells: small-molecule inhibition of the redox function of Ape1

artículo científico publicado en 2008

S-glutathionylation of cysteine 99 in the APE1 protein impairs abasic endonuclease activity.

artículo científico publicado en 2011

Semi-automated high-throughput fluorescent intercalator displacement-based discovery of cytotoxic DNA binding agents from a large compound library

artículo científico publicado en 2010

Small molecule activation of apurinic/apyrimidinic endonuclease 1 reduces DNA damage induced by cisplatin in cultured sensory neurons

artículo científico publicado en 2016

Snapshots of an evolved DNA polymerase pre- and post-incorporation of an unnatural nucleotide

article published in 2018

Staying straight with A-tracts: a DNA analog of the HIV-1 polypurine tract

artículo científico publicado en 2003

Structural and energetic characterization of nucleic acid-binding to the fingers domain of Moloney murine leukemia virus reverse transcriptase.

artículo científico publicado en 2004

Structural basis for a six nucleotide genetic alphabet

artículo científico publicado en 2015

Structure and Biophysics for a Six Letter DNA Alphabet that Includes Imidazo[1,2-a]-1,3,5-triazine-2(8H)-4(3H)-dione (X) and 2,4-Diaminopyrimidine (K).

artículo científico publicado en 2017

Sum1 and Ndt80 proteins compete for binding to middle sporulation element sequences that control meiotic gene expression

artículo científico publicado en 2003

Targeting the OB‐Folds of Replication Protein A with Small Molecules ⬇️

artículo científico publicado el 6 de diciembre de 2010

The DDN catalytic motif is required for Metnase functions in non-homologous end joining (NHEJ) repair and replication restart

artículo científico publicado en 2014

The crystal structure and mutational analysis of a novel RNA-binding domain found in the human Tap nuclear mRNA export factor

artículo científico publicado en 2002

The crystal structure of 5-keto-4-deoxyuronate isomerase from Escherichia coli

artículo científico publicado en 2005

The crystal structure of the monomeric reverse transcriptase from Moloney murine leukemia virus

artículo científico publicado en 2004

The disordered amino-terminus of SIMPL interacts with members of the 70-kDa heat-shock protein family

scientific article published on 01 December 2006

The structure of an authentic spore photoproduct lesion in DNA suggests a basis for recognition

artículo científico publicado en 2014

The structure of an authentic spore photoproduct lesion in DNA suggests a basis for recognition. Corrigendum

scholarly article published in Acta Crystallographica Section D: Biological Crystallography

Toward an Expanded Genome: Structural and Computational Characterization of an Artificially Expanded Genetic Information System

artículo científico publicado en 2017

Unusually strong binding to the DNA minor groove by a highly twisted benzimidazole diphenylether: induced fit and bound water

artículo científico publicado en 2007

Lista de obras de Millie M. Georgiadis

"Skinny" and "Fat" DNA: Two New Double Helices

A high-throughput, high-resolution strategy for the study of site-selective DNA binding agents: analysis of a "highly twisted" benzimidazole-diamidine

A host-guest approach for determining drug-DNA interactions: an example using netropsin

APE1/Ref-1 role in redox signaling: translational applications of targeting the redox function of the DNA repair/redox protein APE1/Ref-1.

Base excision repair apurinic/apyrimidinic endonucleases in apicomplexan parasite Toxoplasma gondii ⬇️

Biochemical characterization of a SET and transposase fusion protein, Metnase: its DNA binding and DNA cleavage activity

Building better DNA polymerases: Engineering the replication of expanded genetic alphabets

Building better enzymes: Molecular basis of improved non-natural nucleobase incorporation by an evolved DNA polymerase

Characterization of critical interactions between Ndt80 and MSE DNA defining a novel family of Ig-fold transcription factors

Characterization of the Redox Activity and Disulfide Bond Formation in Apurinic/Apyrimidinic Endonuclease ⬇️

Consecutive non-natural PZ nucleobase pairs in DNA impact helical structure as seen in 50 μs molecular dynamics simulations

Crystal Structure of a Trypanocidal 4,4′-Bis(imidazolinylamino)diphenylamine Bound to DNA ,

Crystal Structures of GCN2 Protein Kinase C-terminal Domains Suggest Regulatory Differences in Yeast and Mammals

Crystal structure of DNA-bound Co(III)·bleomycin B2: Insights on intercalation and minor groove binding

Crystal structure of the DNA-binding domain from Ndt80, a transcriptional activator required for meiosis in yeast

Crystal structure of the human Hsmar1-derived transposase domain in the DNA repair enzyme Metnase

Crystal structures of oligonucleotides including the integrase processing site of the Moloney murine leukemia virus

Crystallization of and selenomethionine phasing strategy for a SETMAR-DNA complex

Crystallographic studies of a novel DNA-binding domain from the yeast transcriptional activator Ndt80

Differential multimerization of Moloney murine leukemia virus integrase purified under nondenaturing conditions.

Discovery of Macrocyclic Inhibitors of Apurinic/Apyrimidinic Endonuclease 1

Fragment- and structure-based drug discovery for developing therapeutic agents targeting the DNA Damage Response

Functional Analysis of Novel Analogues of E3330 That Block the Redox Signaling Activity of the Multifunctional AP Endonuclease/Redox Signaling Enzyme APE1/Ref-1 ⬇️

Hachimoji DNA and RNA: A genetic system with eight building blocks

High-resolution crystal structures reveal plasticity in the metal binding site of apurinic/apyrimidinic endonuclease I.

Inhibition of apurinic/apyrimidinic endonuclease I's redox activity revisited

Interactions of apurinic/apyrimidinic endonuclease with a redox inhibitor: evidence for an alternate conformation of the enzyme

Novel small-molecule inhibitor of apurinic/apyrimidinic endonuclease 1 blocks proliferation and reduces viability of glioblastoma cells

Phosphorylation of SIMPL modulates RelA-associated NF-kappaB-dependent transcription

Redox regulation of DNA repair: implications for human health and cancer therapeutic development

Role of the multifunctional DNA repair and redox signaling protein Ape1/Ref-1 in cancer and endothelial cells: small-molecule inhibition of the redox function of Ape1

S-glutathionylation of cysteine 99 in the APE1 protein impairs abasic endonuclease activity.

Semi-automated high-throughput fluorescent intercalator displacement-based discovery of cytotoxic DNA binding agents from a large compound library

Small molecule activation of apurinic/apyrimidinic endonuclease 1 reduces DNA damage induced by cisplatin in cultured sensory neurons

Snapshots of an evolved DNA polymerase pre- and post-incorporation of an unnatural nucleotide

Staying straight with A-tracts: a DNA analog of the HIV-1 polypurine tract

Structural and energetic characterization of nucleic acid-binding to the fingers domain of Moloney murine leukemia virus reverse transcriptase.

Structural basis for a six nucleotide genetic alphabet

Structure and Biophysics for a Six Letter DNA Alphabet that Includes Imidazo[1,2-a]-1,3,5-triazine-2(8H)-4(3H)-dione (X) and 2,4-Diaminopyrimidine (K).

Sum1 and Ndt80 proteins compete for binding to middle sporulation element sequences that control meiotic gene expression

Targeting the OB‐Folds of Replication Protein A with Small Molecules ⬇️

The DDN catalytic motif is required for Metnase functions in non-homologous end joining (NHEJ) repair and replication restart

The crystal structure and mutational analysis of a novel RNA-binding domain found in the human Tap nuclear mRNA export factor

The crystal structure of 5-keto-4-deoxyuronate isomerase from Escherichia coli

The crystal structure of the monomeric reverse transcriptase from Moloney murine leukemia virus

The disordered amino-terminus of SIMPL interacts with members of the 70-kDa heat-shock protein family

The structure of an authentic spore photoproduct lesion in DNA suggests a basis for recognition

The structure of an authentic spore photoproduct lesion in DNA suggests a basis for recognition. Corrigendum

Toward an Expanded Genome: Structural and Computational Characterization of an Artificially Expanded Genetic Information System

Unusually strong binding to the DNA minor groove by a highly twisted benzimidazole diphenylether: induced fit and bound water