Filtros de búsqueda

Lista de obras de Arne Klungland

5-Formyluracil and its nucleoside derivatives confer toxicity and mutagenicity to mammalian cells by interfering with normal RNA and DNA metabolism

artículo científico publicado en 2001

8-Oxoguanine-mediated transcriptional mutagenesis causes Ras activation in mammalian cells

artículo científico publicado en 2008

A global DNA repair mechanism involving the Cockayne syndrome B (CSB) gene product can prevent the in vivo accumulation of endogenous oxidative DNA base damage

scientific journal article

A ketogenic diet accelerates neurodegeneration in mice with induced mitochondrial DNA toxicity in the forebrain

artículo científico publicado en 2016

A majority of m6A residues are in the last exons, allowing the potential for 3' UTR regulation

artículo científico publicado en 2015

A novel method for the efficient and selective identification of 5-hydroxymethylcytosine in genomic DNA.

artículo científico publicado en 2011

A novel splice site mutation in the Cockayne syndrome group A gene in two siblings with Cockayne syndrome

artículo científico publicado en 2006

A transgenic minipig model of Huntington's disease shows early signs of behavioral and molecular pathologies

artículo científico publicado en 2018

ALKBH1 is a histone H2A dioxygenase involved in neural differentiation

artículo científico publicado en 2012

ALKBH1-Mediated tRNA Demethylation Regulates Translation

scientific journal article

ALKBH1-Mediated tRNA Demethylation Regulates Translation

artículo científico publicado en 2016

ALKBH4 depletion in mice leads to spermatogenic defects

artículo científico publicado en 2014

ALKBH4-dependent demethylation of actin regulates actomyosin dynamics.

artículo científico publicado en 2013

ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility

artículo científico publicado en 2013

ALKBH5-dependent m6A demethylation controls splicing and stability of long 3'-UTR mRNAs in male germ cells

artículo científico publicado en 2017

ALKBH7 drives a tissue and sex-specific necrotic cell death response following alkylation-induced damage

artículo científico publicado en 2017

ALKBH8-mediated formation of a novel diastereomeric pair of wobble nucleosides in mammalian tRNA

artículo científico publicado en 2011

ALKBHs-facilitated RNA modifications and de-modifications

artículo científico publicado en 2016

Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage

artículo científico publicado en 1999

AlkB homologue 2-mediated repair of ethenoadenine lesions in mammalian DNA.

artículo científico publicado en 2008

Alkbh1 and Tzfp repress a non-repeat piRNA cluster in pachytene spermatocytes

artículo científico publicado en 2012

Base excision repair of oxidative DNA damage activated by XPG protein

artículo científico publicado en 1999

Base removers and strand scissors: different strategies employed in base excision and strand incision at modified base residues in DNA.

artículo científico publicado en 2000

Base-excision repair and beyond --A short summary attributed to scientific achievements of Tomas Lindahl, Nobel Prize Laureate in Chemistry 2015.

artículo científico publicado en 2015

Better late than never for repair of miscoding lesions within a transcribed template

artículo científico publicado en 2003

Biochemical reconstitution of TET1-TDG-BER-dependent active DNA demethylation reveals a highly coordinated mechanism

artículo científico publicado en 2016

Bioinformatics and functional analysis define four distinct groups of AlkB DNA-dioxygenases in bacteria

artículo científico publicado en 2009

Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition.

artículo científico publicado en 2016

Changes of 5-hydroxymethylcytosine distribution during myeloid and lymphoid differentiation of CD34+ cells

artículo científico publicado en 2016

Comparative analysis of 8-oxoG:C, 8-oxoG:A, A:C and C:C DNA repair in extracts from wild type or 8-oxoG DNA glycosylase deficient mammalian and bacterial cells

artículo científico publicado en 2003

Continuous and periodic expansion of CAG repeats in Huntington's disease R6/1 mice

artículo científico publicado en 2010

Corrigendum: Sumoylation of Rap1 mediates the recruitment of TFIID to promote transcription of ribosomal protein genes

artículo científico publicado en 2017

Critical role of aquaporin-4 (AQP4) in astrocytic Ca2+ signaling events elicited by cerebral edema

artículo científico publicado en 2010

DNA base modifications in honey bee and fruit fly genomes suggest an active demethylation machinery with species- and tissue-specific turnover rates

artículo científico publicado en 2016

DNA metabolism: bases of DNA repair and regulation

artículo científico publicado en 2014

DNA repair in mammalian cells: Base excision repair: the long and short of it.

scientific article published on March 2009

DNA repair is indispensable for survival after acute inflammation

artículo científico publicado en 2012

Deficiency in OGG1 protects against inflammation and mutagenic effects associated with H. pylori infection in mouse

artículo científico publicado en 2006

Deficiency of the Cockayne syndrome B (CSB) gene aggravates the genomic instability caused by endogenous oxidative DNA base damage in mice

scientific journal article

Deletion of mouse Alkbh7 leads to obesity

artículo científico publicado en 2013

Diet is not responsible for the presence of several oxidatively damaged DNA lesions in mouse urine

artículo científico publicado en 2004

Differential m6A, m6Am, and m1A Demethylation Mediated by FTO in the Cell Nucleus and Cytoplasm

scientific article published on 06 September 2018

Dynamic RNA modifications in disease

artículo científico

Early-onset lymphoma and extensive embryonic apoptosis in two domain-specific Fen1 mice mutants.

artículo científico publicado en 2008

Effects of Anthocyanins on CAG Repeat Instability and Behaviour in Huntington's Disease R6/1 Mice

artículo científico publicado en 2016

Endogenous DNA Damage and Repair Enzymes: -A short summary of the scientific achievements of Tomas Lindahl, Nobel Laureate in Chemistry 2015.

artículo científico publicado en 2015

Endonuclease G preferentially cleaves 5-hydroxymethylcytosine-modified DNA creating a substrate for recombination

artículo científico publicado en 2014

Evidence that compromised K+ spatial buffering contributes to the epileptogenic effect of mutations in the human Kir4.1 gene (KCNJ10).

artículo científico publicado en 2011

Excision of the doubly methylated base N4,5-dimethylcytosine from DNA by Escherichia coli Nei and Fpg proteins

artículo científico publicado en 2018

Excision of uracil from DNA by hSMUG1 includes strand incision and processing

artículo científico publicado en 2019

Excision of uracil from DNA by the hyperthermophilic Afung protein is dependent on the opposite base and stimulated by heat-induced transition to a more open structure.

artículo científico publicado en 2001

Expression of the E.coli 3-methyladenine DNA glycosylase I gene in mammalian cells reduces the toxic and mutagenic effects of methylating agents ⬇️

artículo científico publicado el 1 de diciembre de 1992

Gene expression profiles in preterm infants on continuous long‑term oxygen therapy suggest reduced oxidative stress‑dependent signaling during hypoxia

artículo científico publicado en 2017

Genome instability and DNA damage accumulation in gene-targeted mice.

artículo científico publicado en 2007

Genome-wide profiling of DNA 5-hydroxymethylcytosine during rat Sertoli cell maturation

artículo científico publicado en 2017

Glial-conditional deletion of aquaporin-4 (Aqp4) reduces blood-brain water uptake and confers barrier function on perivascular astrocyte endfeet

artículo científico publicado en 2011

Histone H3 lysine 27 methylation asymmetry on developmentally-regulated promoters distinguish the first two lineages in mouse preimplantation embryos

artículo científico publicado en 2010

Histone Methylations Define Neural Stem/Progenitor Cell Subtypes in the Mouse Subventricular Zone

artículo científico publicado en 2019

Impaired dynamics and function of mitochondria caused by mtDNA toxicity leads to heart failure

artículo científico publicado en 2015

Incision at hypoxanthine residues in DNA by a mammalian homologue of the Escherichia coli antimutator enzyme endonuclease V

scientific journal article

Increased nuclear DNA damage precedes mitochondrial dysfunction in peripheral blood mononuclear cells from Huntington's disease patients.

artículo científico publicado en 2018

Increased removal of 3-alkyladenine reduces the frequencies of hprt mutations induced by methyl- and ethylmethanesulfonate in Chinese hamster fibroblast cells.

artículo científico publicado en 1994

KDM4A regulates the maternal-to-zygotic transition by protecting broad H3K4me3 domains from H3K9me3 invasion in oocytes

scientific article published on 30 March 2020

Kinetics of endogenous mouse FEN1 in base excision repair.

artículo científico publicado en 2012

Lysine Methylation of the Valosin-Containing Protein (VCP) Is Dispensable for Development and Survival of Mice

artículo científico publicado en 2015

Mammalian ALKBH8 possesses tRNA methyltransferase activity required for the biogenesis of multiple wobble uridine modifications implicated in translational decoding

artículo científico publicado en 2010

Metabolism and DNA repair shape a specific modification pattern in mitochondrial DNA.

artículo científico publicado en 2017

Methylpurine DNA glycosylase of the hyperthermophilic archaeon Archaeoglobus fulgidus

artículo científico publicado en 2002

Mice lacking Alkbh1 display sex-ratio distortion and unilateral eye defects

artículo científico publicado en 2010

Micro chromatin immunoprecipitation (μChIP) from early mammalian embryos

artículo científico publicado en 2015

Mitochondrial DNA toxicity compromises mitochondrial dynamics and induces hippocampal antioxidant defenses

artículo científico publicado en 2011

Mitochondrial DNA toxicity in forebrain neurons causes apoptosis, neurodegeneration, and impaired behavior

artículo científico publicado en 2010

Modeling the impact of mitochondrial DNA damage in forebrain neurons and beyond

artículo científico publicado en 2011

Molecular cloning and functional expression of a human cDNA encoding the antimutator enzyme 8-hydroxyguanine-DNA glycosylase

scientific journal article

Mutations in the RAD27 and SGS1 genes differentially affect the chronological and replicative lifespan of yeast cells growing on glucose and glycerol

artículo científico publicado en 2007

N6-methyladenosine regulates the stability of RNA:DNA hybrids in human cells

artículo científico publicado en 2019

NEIL3-Dependent Regulation of Cardiac Fibroblast Proliferation Prevents Myocardial Rupture

artículo científico publicado en 2017

Neil1 is a genetic modifier of somatic and germline CAG trinucleotide repeat instability in R6/1 mice

artículo científico publicado en 2012

No cancer predisposition or increased spontaneous mutation frequencies in NEIL DNA glycosylases-deficient mice

artículo científico publicado en 2017

Nobel Prize for genetic modification

artículo científico publicado en 2007

Non-homologous functions of the AlkB homologs

artículo científico

Nucleocytoplasmic Shuttling of FTO Does Not Affect Starvation-Induced Autophagy

artículo científico publicado en 2017

OGG1 initiates age-dependent CAG trinucleotide expansion in somatic cells

scientific article published on 22 April 2007

Organ and cell specificity of base excision repair mutants in mice

artículo científico publicado en 2007

Oxidative damage to purines in DNA: role of mammalian Ogg1.

artículo científico publicado en 2006

Oxidative stress causes DNA triplet expansion in Huntington's disease mouse embryonic stem cells

artículo científico publicado en 2013

Oxidized C5-methyl cytosine bases in DNA: 5-Hydroxymethylcytosine; 5-formylcytosine; and 5-carboxycytosine

artículo científico publicado en 2016

Positioning Europe for the EPITRANSCRIPTOMICS challenge.

artículo científico publicado en 2018

Proliferation failure and gamma radiation sensitivity of Fen1 null mutant mice at the blastocyst stage

scientific journal article

Protozoan ALKBH8 oxygenases display both DNA repair and tRNA modification activities

artículo científico publicado en 2014

Pull-down of 5-hydroxymethylcytosine DNA using JBP1-coated magnetic beads

artículo científico publicado en 2012

Purification and properties of the alkylation repair DNA glycosylase encoded the MAG gene from Saccharomyces cerevisiae.

artículo científico publicado en 1995

RNA m6A methylation participates in regulation of postnatal development of the mouse cerebellum.

artículo científico publicado en 2018

Reconstitution of DNA base excision-repair with purified human proteins: interaction between DNA polymerase beta and the XRCC1 protein

artículo científico publicado en 1996

Removal of aquaporin-4 from glial and ependymal membranes causes brain water accumulation

artículo científico publicado en 2016

Repair and Processing Events at DNA Ends ⬇️

artículo científico publicado el 1 de enero de 1997

Repair and mutagenesis at oxidized DNA lesions in the developing brain of wild-type and Ogg1-/- mice.

artículo científico publicado en 2006

Repair deficient mice reveal mABH2 as the primary oxidative demethylase for repairing 1meA and 3meC lesions in DNA

artículo científico publicado en 2006

Repeated inhalations of diesel exhaust particles and oxidatively damaged DNA in young oxoguanine DNA glycosylase (OGG1) deficient mice

artículo científico publicado en 2007

Reversible RNA modifications in meiosis and pluripotency

artículo científico publicado en 2016

Reversible inactivation of E. coli endonuclease III via modification of its [4Fe-4S] cluster by nitric oxide

artículo científico publicado en 2003

Role of ALKBH1 in the Core Transcriptional Network of Embryonic Stem Cells

artículo científico publicado en 2016

Role of the DNA repair glycosylase OGG1 in the activation of murine splenocytes.

artículo científico

STIM1 R304W causes muscle degeneration and impaired platelet activation in mice

artículo científico publicado en 2018

Second pathway for completion of human DNA base excision-repair: reconstitution with purified proteins and requirement for DNase IV (FEN1).

artículo científico publicado en 1997

Sequencing of FTO and ALKBH5 in men undergoing infertility work-up identifies an infertility-associated variant and two missense mutations.

artículo científico publicado en 2016

Spontaneous mutagenesis in Csb(m/m)Ogg1⁻(/)⁻ mice is attenuated by dietary resveratrol

artículo científico publicado en 2010

Sprouts of RNA epigenetics: the discovery of mammalian RNA demethylases.

artículo científico publicado en 2013

Structural basis for enzymatic excision of N1-methyladenine and N3-methylcytosine from DNA

artículo científico publicado en 2007

Substantial decrease of urinary 8-oxo-7,8-dihydroguanine, a product of the base excision repair pathway, in DNA glycosylase defective mice

artículo científico publicado en 2005

Sumoylation of Rap1 mediates the recruitment of TFIID to promote transcription of ribosomal protein genes

artículo científico publicado en 2015

Synergistic Actions of Ogg1 and Mutyh DNA Glycosylases Modulate Anxiety-like Behavior in Mice

artículo científico publicado en 2015

TORC1-dependent sumoylation of Rpc82 promotes RNA polymerase III assembly and activity.

artículo científico publicado en 2017

The DNA dioxygenase ALKBH2 protects Arabidopsis thaliana against methylation damage

artículo científico publicado en 2012

The hyperthermophilic euryarchaeon Archaeoglobus fulgidus repairs uracil by single-nucleotide replacement

artículo científico publicado en 2010

The presence of 5-hydroxymethylcytosine at the gene promoter and not in the gene body negatively regulates gene expression

artículo científico publicado en 2011

Tolerated wobble mutations in siRNAs decrease specificity, but can enhance activity in vivo

artículo científico publicado en 2005

Transcription activities at 8-oxoG lesions in DNA.

artículo científico publicado en 2004

Tzfp represses the androgen receptor in mouse testis

artículo científico publicado en 2013

Uracil-DNA glycosylase of Thermoplasma acidophilum directs long-patch base excision repair, which is promoted by deoxynucleoside triphosphates and ATP/ADP, into short-patch repair

artículo científico publicado en 2011

Urinary excretion of DNA repair products correlates with metabolic rates as well as with maximum life spans of different mammalian species.

artículo científico publicado en 2004

Waves of sumoylation support transcription dynamics during adipocyte differentiation

artículo científico publicado en 2022

X-linked Angelman-like syndrome caused by Slc9a6 knockout in mice exhibits evidence of endosomal-lysosomal dysfunction.

artículo científico publicado en 2011

Ythdf2-mediated m6A mRNA clearance modulates neural development in mice

artículo científico publicado en 2018

[Life without DNA repair]

scientific article published on 01 January 2001

Dominio Público Uruguay está sostenido por:

Acerca de Dominio Público Uruguay

Ayuda