Lista de obras -

Alterations in growth and apoptosis of insulin receptor substrate-1-deficient beta-cells.

artículo científico publicado en 2005

Breathing room: the (un)natural history of adipose microhypoxia and insulin resistance

artículo científico publicado en 2009

Correction for Long et al., "Insulin Receptor Substrates Irs1 and Irs2 Coordinate Skeletal Muscle Growth and Metabolism via the Akt and AMPK Pathways". ⬇️

artículo científico publicado en 2017

Deletion of Irs2 causes reduced kidney size in mice: role for inhibition of GSK3beta?

artículo científico publicado en 2010

Direct autocrine action of insulin on β-cells: does it make physiological sense?

artículo científico publicado en 2013

Essential role of protein kinase C zeta in the impairment of insulin-induced glucose transport in IRS-2-deficient brown adipocytes

artículo científico publicado en 2003

Exendin-4 uses Irs2 signaling to mediate pancreatic beta cell growth and function

artículo científico publicado en 2005

Foxo1 integrates insulin signaling with mitochondrial function in the liver

artículo científico publicado en 2009

IRS-2 pathways integrate female reproduction and energy homeostasis

artículo científico publicado en 2000

IRS1Ser³⁰⁷ phosphorylation does not mediate mTORC1-induced insulin resistance

artículo científico publicado en 2013

IRS2 increases mitochondrial dysfunction and oxidative stress in a mouse model of Huntington disease ⬇️

artículo científico publicado el 19 de septiembre de 2011

IRS2 signaling in LepR-b neurons suppresses FoxO1 to control energy balance independently of leptin action ⬇️

artículo científico publicado el 2 de mayo de 2012

Insulin receptor substrate 2 is essential for maturation and survival of photoreceptor cells.

artículo científico publicado en 2005

Insulin receptor substrate 2 plays diverse cell-specific roles in the regulation of glucose transport

artículo científico publicado en 2005

Insulin receptor substrate-2 deficiency impairs brain growth and promotes tau phosphorylation

artículo científico publicado en 2003

Insulin receptor substrate-2 is expressed in kidney epithelium and up-regulated in diabetic nephropathy

artículo científico publicado en 2013

Insulin receptor substrates Irs1 and Irs2 coordinate skeletal muscle growth and metabolism via the Akt and AMPK pathways

artículo científico publicado en 2010

Insulin resistance in thermally-injured rats is associated with post-receptor alterations in skeletal muscle, liver and adipose tissue.

artículo científico publicado en 2004

Insulin signaling meets mitochondria in metabolism

artículo científico publicado en 2010

Insulin-like growth factor 2 and the insulin receptor, but not insulin, regulate fetal hepatic glycogen synthesis

scientific journal article

Integrating metabolism and longevity through insulin and IGF1 signaling

scientific article published on 21 December 2012

Irs1 and Irs2 signaling is essential for hepatic glucose homeostasis and systemic growth

artículo científico publicado en 2005

Irs1 serine 307 promotes insulin sensitivity in mice

artículo científico publicado en 2010

Irs2 and Irs4 synergize in non-LepRb neurons to control energy balance and glucose homeostasis

scientific article published on 23 October 2013

Islet-sparing effects of protein tyrosine phosphatase-1b deficiency delays onset of diabetes in IRS2 knockout mice

artículo científico publicado en 2004

Molecular mechanism(s) of burn-induced insulin resistance in murine skeletal muscle: role of IRS phosphorylation

artículo científico publicado en 2005

Nutrient-dependent and insulin-stimulated phosphorylation of insulin receptor substrate-1 on serine 302 correlates with increased insulin signaling

artículo científico publicado en 2003

Pdx1 restores beta cell function in Irs2 knockout mice

artículo científico publicado en 2002

Phosphatase and tensin homolog regulation of islet growth and glucose homeostasis

artículo científico publicado en 2005

Phosphorylation of Irs1 at SER-522 inhibits insulin signaling

artículo científico publicado en 2007

Pulsatile portal vein insulin delivery enhances hepatic insulin action and signaling

artículo científico publicado en 2012

RIP-Cre revisited, evidence for impairments of pancreatic beta-cell function

artículo científico publicado en 2005

Regulation of glucose homeostasis through a XBP-1–FoxO1 interaction ⬇️

artículo científico publicado el 13 de febrero de 2011

Serine 302 Phosphorylation of Mouse Insulin Receptor Substrate 1 (IRS1) Is Dispensable for Normal Insulin Signaling and Feedback Regulation by Hepatic S6 Kinase

artículo científico publicado en 2016

The AKTion in non-canonical insulin signaling ⬇️

artículo científico publicado el 6 de marzo de 2012

The Irs1 branch of the insulin signaling cascade plays a dominant role in hepatic nutrient homeostasis

scientific article published on 13 July 2009

The reciprocal stability of FOXO1 and IRS2 creates a regulatory circuit that controls insulin signaling.

artículo científico publicado en 2006

The repression of IRS2 gene by ATF3, a stress-inducible gene, contributes to pancreatic beta-cell apoptosis

artículo científico publicado en 2007

Trimeprazine increases IRS2 in human islets and promotes pancreatic β cell growth and function in mice

artículo científico publicado en 2016

Upregulation of insulin receptor substrate-2 in pancreatic beta cells prevents diabetes

artículo científico publicado en 2003

Upregulation of insulin receptor substrate-2 in pancreatic β cells prevents diabetes

article by Anita M. Hennige et al published 15 November 2003 in Journal of Clinical Investigation

c-Jun N-terminal kinase (JNK) mediates feedback inhibition of the insulin signaling cascade

artículo científico publicado en 2002

cAMP promotes pancreatic beta-cell survival via CREB-mediated induction of IRS2.

artículo científico publicado en 2003

kNOXing on the Door of Selective Insulin Resistance ⬇️

artículo científico publicado el 1 de mayo de 2012

Lista de obras de

Alterations in growth and apoptosis of insulin receptor substrate-1-deficient beta-cells.

Breathing room: the (un)natural history of adipose microhypoxia and insulin resistance

Correction for Long et al., "Insulin Receptor Substrates Irs1 and Irs2 Coordinate Skeletal Muscle Growth and Metabolism via the Akt and AMPK Pathways". ⬇️

Deletion of Irs2 causes reduced kidney size in mice: role for inhibition of GSK3beta?

Direct autocrine action of insulin on β-cells: does it make physiological sense?

Essential role of protein kinase C zeta in the impairment of insulin-induced glucose transport in IRS-2-deficient brown adipocytes

Exendin-4 uses Irs2 signaling to mediate pancreatic beta cell growth and function

Foxo1 integrates insulin signaling with mitochondrial function in the liver

IRS-2 pathways integrate female reproduction and energy homeostasis

IRS1Ser³⁰⁷ phosphorylation does not mediate mTORC1-induced insulin resistance

IRS2 increases mitochondrial dysfunction and oxidative stress in a mouse model of Huntington disease ⬇️

IRS2 signaling in LepR-b neurons suppresses FoxO1 to control energy balance independently of leptin action ⬇️

Insulin receptor substrate 2 is essential for maturation and survival of photoreceptor cells.

Insulin receptor substrate 2 plays diverse cell-specific roles in the regulation of glucose transport

Insulin receptor substrate-2 deficiency impairs brain growth and promotes tau phosphorylation

Insulin receptor substrate-2 is expressed in kidney epithelium and up-regulated in diabetic nephropathy

Insulin receptor substrates Irs1 and Irs2 coordinate skeletal muscle growth and metabolism via the Akt and AMPK pathways

Insulin resistance in thermally-injured rats is associated with post-receptor alterations in skeletal muscle, liver and adipose tissue.

Insulin signaling meets mitochondria in metabolism

Insulin-like growth factor 2 and the insulin receptor, but not insulin, regulate fetal hepatic glycogen synthesis

Integrating metabolism and longevity through insulin and IGF1 signaling

Irs1 and Irs2 signaling is essential for hepatic glucose homeostasis and systemic growth

Irs1 serine 307 promotes insulin sensitivity in mice

Irs2 and Irs4 synergize in non-LepRb neurons to control energy balance and glucose homeostasis

Islet-sparing effects of protein tyrosine phosphatase-1b deficiency delays onset of diabetes in IRS2 knockout mice

Molecular mechanism(s) of burn-induced insulin resistance in murine skeletal muscle: role of IRS phosphorylation

Nutrient-dependent and insulin-stimulated phosphorylation of insulin receptor substrate-1 on serine 302 correlates with increased insulin signaling

Pdx1 restores beta cell function in Irs2 knockout mice

Phosphatase and tensin homolog regulation of islet growth and glucose homeostasis

Phosphorylation of Irs1 at SER-522 inhibits insulin signaling

Pulsatile portal vein insulin delivery enhances hepatic insulin action and signaling

RIP-Cre revisited, evidence for impairments of pancreatic beta-cell function

Regulation of glucose homeostasis through a XBP-1–FoxO1 interaction ⬇️

Serine 302 Phosphorylation of Mouse Insulin Receptor Substrate 1 (IRS1) Is Dispensable for Normal Insulin Signaling and Feedback Regulation by Hepatic S6 Kinase

The AKTion in non-canonical insulin signaling ⬇️

The Irs1 branch of the insulin signaling cascade plays a dominant role in hepatic nutrient homeostasis

The reciprocal stability of FOXO1 and IRS2 creates a regulatory circuit that controls insulin signaling.

The repression of IRS2 gene by ATF3, a stress-inducible gene, contributes to pancreatic beta-cell apoptosis

Trimeprazine increases IRS2 in human islets and promotes pancreatic β cell growth and function in mice

Upregulation of insulin receptor substrate-2 in pancreatic beta cells prevents diabetes

Upregulation of insulin receptor substrate-2 in pancreatic β cells prevents diabetes

c-Jun N-terminal kinase (JNK) mediates feedback inhibition of the insulin signaling cascade

cAMP promotes pancreatic beta-cell survival via CREB-mediated induction of IRS2.

kNOXing on the Door of Selective Insulin Resistance ⬇️