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Lista de obras de Laurie Glimcher

1,25-Dihydroxyvitamin D3 inhibits antigen-induced T cell activation

artículo científico publicado el 1 de octubre de 1984

A DNA binding protein regulated by IL-4 and by differentiation in B cells

artículo científico publicado en 1988

A biochemical analysis of Ak molecules from mutant antigen presenting cell lines

scientific article published on 01 January 1986

A cDNA for a human cyclic AMP response element-binding protein which is distinct from CREB and expressed preferentially in brain

artículo científico publicado en 1990

A cell type-specific enhancer in the human B7.1 gene regulated by NF-kappaB

artículo científico publicado en 1996

A common factor regulates both Th1- and Th2-specific cytokine gene expression

artículo científico publicado en 1994

A dominant mutation within the DNA-binding domain of the bZIP transcription factor Maf causes murine cataract and results in selective alteration in DNA binding

artículo científico publicado en 2003

A functional role for signal transduction via the cytoplasmic domains of MHC class II proteins

artículo científico publicado en 1989

A lipopolysaccharide-induced DNA-binding protein for a class II gene in B cells is distinct from NF-kappa B.

artículo científico publicado en 1989

A lipopolysaccharide-specific enhancer complex involving Ets, Elk-1, Sp1, and CREB binding protein and p300 is recruited to the tumor necrosis factor alpha promoter in vivo

artículo científico publicado en 2000

A mammalian homolog of Drosophila schnurri, KRC, regulates TNF receptor-driven responses and interacts with TRAF2

artículo científico publicado en 2002

A minimal level of MHC class II expression is sufficient to abrogate autoreactivity

artículo científico publicado en 1999

A multiply redundant genetic switch 'locks in' the transcriptional signature of regulatory T cells

artículo científico publicado en 2012

A new member of the leucine zipper class of proteins that binds to the HLA DR alpha promoter

scientific journal article

A novel group of phospholipase A2s preferentially expressed in type 2 helper T cells

scientific journal article

A novel role of CD4 Th17 cells in mediating cardiac allograft rejection and vasculopathy

artículo científico publicado en 2008

A novel transcription factor, T-bet, directs Th1 lineage commitment

artículo científico publicado en 2000

A potential role for the nuclear factor of activated T cells family of transcriptional regulatory proteins in adipogenesis

artículo científico publicado en 1998

A role for the immunological synapse in lineage commitment of CD4 lymphocytes

artículo científico publicado en 2004

A single base mutation in an I-A alpha-chain gene alters T-cell recognition

artículo científico publicado en 1987

A tissue-specific DNase I-hypersensitive site in a class II A alpha gene is under trans-regulatory control

artículo científico publicado en 1988

Absence of MHC class II molecules reduces CNS demyelination, microglial/macrophage infiltration, and twitching in murine globoid cell leukodystrophy

artículo científico publicado en 1994

Absence of the T-bet gene coding for the Th1-related transcription factor does not affect diabetes-associated phenotypes in Balb/c mice

artículo científico publicado en 2003

Absence of transcription factor c-maf causes abnormal terminal differentiation of hypertrophic chondrocytes during endochondral bone development

artículo científico publicado el 1 de octubre de 2003

Activation of T cells by superantigen in class II-negative mice.

artículo científico publicado en 1994

Administration of BMP2/7 in utero partially reverses Rubinstein-Taybi syndrome-like skeletal defects induced by Pdk1 or Cbp mutations in mice

artículo científico publicado en 2011

Administration of BMP2/7 in utero partially reverses Rubinstein-Taybi syndrome?like skeletal defects induced by Pdk1 or Cbp mutations in mice

artículo científico publicado en 2012

After GWAS: mice to the rescue?

artículo científico publicado el 29 de septiembre de 2012

Alteration of a non-polymorphic residue in a class II E beta gene eliminates an antibody-defined epitope without affecting T cell recognition

artículo científico publicado en 1987

Amelioration of neurodegenerative diseases by cell death-induced cytoplasmic delivery of humanin.

artículo científico publicado en 2013

An HLA-DR? promoter DNA-binding protein is expressed ubiquitously and maps to human chromosomes 22 and 5

artículo científico publicado el 1 de enero de 1991

An Ia-positive mouse T-cell clone is functional in presenting antigen to other T cells.

artículo científico publicado en 1985

An MHC interaction site maps to the amino-terminal half of the T cell receptor α chain variable domain

artículo científico publicado el 12 de junio de 1992

An essential role in liver development for transcription factor XBP-1

scientific journal article

An inflammation-targeting hydrogel for local drug delivery in inflammatory bowel disease

artículo científico publicado en 2015

An innate cell-mediated, murine ulcerative colitis-like syndrome in the absence of nuclear factor of activated T cells

artículo científico publicado en 2004

An intronic 10-base-pair deletion in a class II A beta gene affects RNA processing

artículo científico publicado en 1989

An isotype-specific activator of major histocompatibility complex (MHC) class II genes that is independent of class II transactivator

artículo científico publicado en 1997

Analysis of responder cell-cell interactions in the syngeneic mixed leukocyte response

artículo científico publicado en 1985

Antigen presentation abrogated in cells expressing truncated Ia molecules

scientific article published on 01 March 1989

Antigen-driven effector CD8 T cell function regulated by T-bet

artículo científico publicado en 2003

Arginine methylation of NIP45 modulates cytokine gene expression in effector T lymphocytes

artículo científico publicado en 2004

Asthmatic changes in mice lacking T-bet are mediated by IL-13.

artículo científico publicado en 2005

Author Correction: XBP-1 and the unfolded protein response (UPR)

artículo científico publicado en 2020

Autoimmune diabetes can be induced in transgenic major histocompatibility complex class II-deficient mice

artículo científico publicado en 1993

B lymphocyte development and activation independent of MHC class II expression

scientific article published on 01 February 1993

B7 expression on thymic medullary epithelium correlates with epithelium-mediated deletion of V beta 5+ thymocytes

artículo científico publicado en 1994

B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy

artículo científico publicado en 1995

B7-2 (CD86) is essential for the development of IL-4-producing T cells

article

BAX inhibitor-1 is a negative regulator of the ER stress sensor IRE1alpha

artículo científico publicado en 2009

BanI polymorphism at the XBP1 locus

artículo científico publicado en 1990

Bcl-2 is upregulated at the CD4+ CD8+ stage during positive selection and promotes thymocyte differentiation at several control points

artículo científico publicado en 1994

Bifidobacterium animalis subsp. lactis fermented milk product reduces inflammation by altering a niche for colitogenic microbes

artículo científico publicado en 2010

Binding of toxic shock syndrome toxin-1 to murine major histocompatibility complex class II molecules

artículo científico publicado en 1990

Biochemical characterization of I-Ak proteins from mutant antigen-presenting B-cell--B-lymphoma hybridomas

artículo científico publicado en 1985

Blockade of CD86 ameliorates Leishmania major infection by down-regulating the Th2 response

scientific article published on 01 December 1996

Both L3T4+ and Lyt-2+ helper T cells initiate cytotoxic T lymphocyte responses against allogenic major histocompatibility antigens but not against trinitrophenyl-modified self

artículo científico publicado en 1985

Breaking down barriers to clinical translation: an interview with Laurie Glimcher. Interview by Sarah Allan

artículo científico publicado en 2012

CD8+ effector cells responding to residual class I antigens, with help from CD4+ cells stimulated indirectly, cause rejection of "major histocompatibility complex-deficient" skin grafts

scientific article published on 01 April 1997

CIITA-dependent and -independent class II MHC expression revealed by a dominant negative mutant

artículo científico publicado en 1997

Calcineurin regulates innate antifungal immunity in neutrophils

artículo científico publicado en 2010

Cartilage-specific ablation of XBP1 signaling in mouse results in a chondrodysplasia characterized by reduced chondrocyte proliferation and delayed cartilage maturation and mineralization

artículo científico publicado en 2015

Casein expression in cytotoxic T lymphocytes

artículo científico publicado en 1990

Cdh1 regulates osteoblast function through an APC/C-independent modulation of Smurf1.

artículo científico publicado en 2011

Chondrodysplasia and neurological abnormalities in ATF-2-deficient mice

artículo científico publicado en 1996

Class II major histocompatibility complex-deficient mice initially control an infection with Leishmania major but succumb to the disease

artículo científico publicado en 1995

Class II-positive hematopoietic cells cannot mediate positive selection of CD4+ T lymphocytes in class II-deficient mice

artículo científico publicado en 1993

Cloning of an interleukin-4 inducible gene from cytotoxic T lymphocytes and its identification as a lipase

artículo científico publicado en 1990

Colitis-associated colorectal cancer driven by T-bet deficiency in dendritic cells

scientific article published on September 2009

Communicable ulcerative colitis induced by T-bet deficiency in the innate immune system

artículo científico publicado en 2007

Complex regulation of class II gene expression: analysis with class II mutant cell lines

scientific article published on 01 November 1985

Constitutive expression of B7 restores immunogenicity of tumor cells expressing truncated major histocompatibility complex class II molecules

artículo científico publicado el 15 de junio de 1993

Constraints in antigen presentation severely restrict T cell recognition of the allogeneic fetus

artículo científico publicado en 2007

Control of T helper cell differentiation through cytokine receptor inclusion in the immunological synapse

artículo científico publicado en 2009

Control of bone resorption in mice by Schnurri-3.

artículo científico publicado en 2012

Control of immunoglobulin heavy chain constant region gene expression

artículo científico publicado en 1991

Control of postnatal bone mass by the zinc finger adapter protein Schnurri-3.

artículo científico publicado en 2007

Control of transcription at the murine A alpha locus

artículo científico publicado en 1990

Coordinate and cooperative roles for NF-AT and AP-1 in the regulation of the murine IL-4 gene

artículo científico

Corticosteroid induction of Ig+Ia- B cells in vitro is mediated via interaction with the glucocorticoid cytoplasmic receptor

scientific article published on 01 April 1988

Critical roles for transcription factor GATA-3 in thymocyte development

scientific journal article

Crystal structure of the DNA binding domain of the transcription factor T-bet suggests simultaneous recognition of distant genome sites

artículo científico publicado en 2016

Cutting Edge: STAT1 and T-bet Play Distinct Roles in Determining Outcome of Visceral Leishmaniasis Caused by Leishmania donovani

scientific article published on 01 July 2006

Cytoplasmic domain affects membrane expression and function of an Ia molecule

artículo científico publicado en 1988

DNA-mediated transfer of major histocompatibility class II I-Ab and I-Abm12 genes into B lymphoma cells: molecular and functional analysis of introduced antigens.

artículo científico publicado en 1985

Dampening of death pathways by schnurri-2 is essential for T-cell development

artículo científico publicado el 7 de abril de 2011

Decreased immediate inflammatory gene induction in activating transcription factor-2 mutant mice

artículo científico publicado en 2001

Delayed Lymphoid Repopulation with Defects in IL-4–Driven Responses Produced by Inactivation of NF-ATc

artículo científico publicado el 1 de enero de 1998

Delayed rejection of soluble tumor necrosis factor receptor-secreting tumor allografts

artículo científico publicado el 15 de enero de 1998

Dendritic cell expression of the transcription factor T-bet regulates mast cell progenitor homing to mucosal tissue.

artículo científico publicado en 2007

Depletion of CD4+ T cells in major histocompatibility complex class II-deficient mice

artículo científico publicado en 1991

Development of Spontaneous Airway Changes Consistent with Human Asthma in Mice Lacking T-bet

artículo científico publicado el 11 de enero de 2002

Developmental and cytokine-mediated regulation of MHC class II gene promoter occupancy in vivo

artículo científico publicado en 1993

Differences in DNA sequence specificity among MHC class II X box binding proteins

artículo científico

Differential effects of unfolded protein response pathways on axon injury-induced death of retinal ganglion cells.

artículo científico publicado en 2012

Differential expression of T-bet, a T-box transcription factor required for Th1 T-cell development, in peripheral T-cell lymphomas

artículo científico publicado en 2003

Differential induction of class II gene expression in murine pre-B-cell lines by B-cell stimulatory factor-1 and by antibodies to B-cell surface antigens

artículo científico publicado en 1988

Differing regulation and function of ICAM-1 and class II antigens on renal tubular cells

artículo científico publicado en 1990

Direct evidence that a class II molecule and a simple globular protein generate multiple determinants

artículo científico publicado en 1985

Dissociation of inositol-requiring enzyme (IRE1α)-mediated c-Jun N-terminal kinase activation from hepatic insulin resistance in conditional X-box-binding protein-1 (XBP1) knock-out mice

artículo científico publicado en 2011

Distal regions of the human IFNG locus direct cell type-specific expression

artículo científico publicado en 2010

Distinct Effects of T-bet in T H 1 Lineage Commitment and IFN-γ Production in CD4 and CD8 T Cells

artículo científico publicado el 11 de enero de 2002

Distinct cloned class II MHC DNA binding proteins recognize the X box transcription element

scientific article published on 01 October 1988

Dominant negative mutants of transcription factor mXBP (CRE-BP1, ATF-2)

artículo científico publicado en 1992

Dual and opposing roles of the unfolded protein response regulated by IRE1alpha and XBP1 in proinsulin processing and insulin secretion

artículo científico publicado en 2011

ER Stress Sensor XBP1 Controls Anti-tumor Immunity by Disrupting Dendritic Cell Homeostasis

artículo científico publicado en 2015

Early murine Lyme carditis has a macrophage predominance and is independent of major histocompatibility complex class II-CD4+ T cell interactions

artículo científico publicado en 1995

Editorial overview

scientific article published on 23 December 2010

Ek beta mutant antigen-presenting cell lines expressing altered Ak alpha molecules

artículo científico publicado en 1986

Endoplasmic reticulum stress in immunity

artículo científico

Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes

scientific journal article

Enhanced MHC class II expression in renal proximal tubules precedes loss of renal function in MRL/lpr mice with lupus nephritis

artículo científico publicado en 1989

Enterobacteriaceae act in concert with the gut microbiota to induce spontaneous and maternally transmitted colitis

artículo científico publicado en 2010

Evidence that a "four-cell cluster" may prime cytotoxic T-cells during graft rejection

scientific article published on 01 February 1993

Evidence that autoreactive T hybridomas recognize multiple epitopes on the I-Ak molecule

artículo científico publicado en 1985

Excess of rare variants in non-genome-wide association study candidate genes in patients with hypertriglyceridemia

artículo científico publicado en 2011

Expression of T-bet by CD4 T cells is essential for resistance to Salmonella infection.

artículo científico publicado en 2005

Expression of metalloproteinases in pigmented villonodular synovitis

scientific article published on 01 August 1994

Expression of the T-cell-specific gamma gene is unnecessary in T cells recognizing class II MHC determinants

artículo científico publicado en 1985

Extensive pancreas regeneration following acinar-specific disruption of Xbp1 in mice

artículo científico

Fine specificity of cloned insulin-specific T cell hybridomas: evidence supporting a role for tertiary conformation

artículo científico publicado el 1 de diciembre de 1983

Fine-tuning of the unfolded protein response: Assembling the IRE1alpha interactome

artículo científico publicado en 2009

From sugar to fat: How the transcription factor XBP1 regulates hepatic lipogenesis

artículo científico publicado en 2009

Functional Activity of a Transformed Thymic Epithelial Cell Line

artículo científico publicado el 1 de enero de 1983

Functional Th1 cells are required for surgical adhesion formation in a murine model

scientific article published on May 2008

Functional and molecular characterization of I-A kappa beta mutants is consistent with the predicted three dimensional structure of class II MHC molecules

artículo científico publicado en 1990

Functional expression of a cloned I-A beta k gene in B-lymphoma cells

artículo científico publicado en 1984

Genes that regulate interleukin-4 expression in T cells

artículo científico publicado el 1 de diciembre de 1997

Genetic evidence for a new type of major histocompatibility complex class II combined immunodeficiency characterized by a dyscoordinate regulation of HLA-D alpha and beta chains

artículo científico publicado en 1996

Gout: new insights into an old disease.

artículo científico publicado en 2006

HCO3-/Cl- anion exchanger SLC4A2 is required for proper osteoclast differentiation and function

artículo científico publicado en 2008

Harvard's women four years later

artículo científico publicado en 2009

Homeostasis and inflammation in the intestine

artículo científico publicado en 2010

How we can help the next generation of scientists: introducing The "Hands-On" Primary Caregiver's Support Program

artículo científico publicado en 2004

Human MHC class II gene transcription directed by the carboxyl terminus of CIITA, one of the defective genes in type II MHC combined immune deficiency

artículo científico publicado en 1995

Human T-bet Governs Innate and Innate-like Adaptive IFN-γ Immunity against Mycobacteria

scientific article published on 03 December 2020

Human X-box-binding protein 1 is required for the transcription of a subset of human class II major histocompatibility genes and forms a heterodimer with c-fos

artículo científico publicado en 1991

Human cytomegalovirus protein US11 provokes an unfolded protein response that may facilitate the degradation of class I major histocompatibility complex products

artículo científico publicado en 2005

Hyperproliferation and dysregulation of IL-4 expression in NF-ATp-deficient mice

artículo científico publicado en 1996

I region-restricted antigen presentation by B cell–B lymphoma hybridomas

artículo científico publicado el 15 de julio de 1982

IA mutant functional antigen-presenting cell lines

artículo científico publicado el 1 de mayo de 1983

IL-2 production in developing Th1 cells is regulated by heterodimerization of RelA and T-bet and requires T-bet serine residue 508.

artículo científico publicado en 2005

IL-21 induces antiviral microRNA-29 in CD4 T cells to limit HIV-1 infection

artículo científico publicado en 2015

IL-23 receptor regulates unconventional IL-17-producing T cells that control bacterial infections

artículo científico publicado en 2010

IRE1α activation protects mice against acetaminophen-induced hepatotoxicity

artículo científico publicado en 2012

IRE1α-XBP1 controls T cell function in ovarian cancer by regulating mitochondrial activity

artículo científico publicado en 2018

IRE1α-XBP1 signaling in leukocytes controls prostaglandin biosynthesis and pain

scientific article published on 01 July 2019

Ia antigen-bearing B cell tumor lines can present protein antigen and alloantigen in a major histocompatibility complex-restricted fashion to antigen-reactive T cells

artículo científico publicado en 1982

Identification of a cell-surface antigen selectively expressed on the natural killer cell

artículo científico publicado el 1 de enero de 1977

Identification of a conserved lipopolysaccharide-plus-interleukin-4-responsive element located at the promoter of germ line epsilon transcripts

artículo científico publicado en 1991

Identification of an IL-4-inducible gene expressed in differentiating lymphocytes and male germ cells

artículo científico publicado en 1990

Identification of c-myc promoter-binding protein and X-box binding protein 1 as interleukin-6 target genes in human multiple myeloma cells

artículo científico publicado en 1999

Identification of functional regions on the I-Ab molecule by site-directed mutagenesis

artículo científico publicado en 1986

Immune responses in MHC class II-deficient mice

artículo científico publicado en 1995

Immunogenetic Analysis of "Natural Killer" Activity in the Mouse

artículo científico publicado el 1 de enero de 1979

Immunoregulatory effects of superantigens: interactions of staphylococcal enterotoxins with host MHC and non-MHC products

artículo científico publicado en 1993

In situ hybridization studies of stromelysin and collagenase messenger RNA expression in rheumatoid synovium

artículo científico publicado en 1991

In situ hybridization studies suggest a role for the basic region‐leucine zipper protein hXBP‐1 in exocrine gland and skeletal development during mouse embryogenesis

artículo científico publicado el 1 de junio de 1993

In vivo footprinting of MHC class II genes: bare promoters in the bare lymphocyte syndrome

artículo científico publicado en 1991

Increased bone mass and bone matrix mineralization in schnurri-3 null mice

Increased bone matrix mineralization in Schnurri-3 null mice

article published in 2009

Increased susceptibility of mice lacking T-bet to infection with Mycobacterium tuberculosis correlates with increased IL-10 and decreased IFN-gamma production

artículo científico publicado en 2005

Indirect recognition by helper cells can induce donor-specific cytotoxic T lymphocytes in vivo

artículo científico publicado en 1994

Influence of accessory cell and T cell surface antigens on mitogen-induced IL 2 receptor expression

artículo científico publicado en 1985

Inhibition of IFN-gamma induction of class II MHC genes by cAMP and prostaglandins

artículo científico publicado en 1994

Inhibitory function of two NFAT family members in lymphoid homeostasis and Th2 development

artículo científico publicado en 1998

Intercellular adhesion molecule-1 (ICAM-1) expression is upregulated in autoimmune murine lupus nephritis

artículo científico publicado en 1990

Interferon gamma regulates binding of two nuclear protein complexes in a macrophage cell line

scientific article published on February 1990

Interferon regulatory factor 4 (IRF4) interacts with NFATc2 to modulate interleukin 4 gene expression

artículo científico publicado en 2002

Intersection of the unfolded protein response and hepatic lipid metabolism

artículo científico publicado en 2009

Interspecies comparison of human and murine scleroderma reveals IL-13 and CCL2 as disease subset-specific targets

artículo científico publicado en 2012

Intrinsic susceptibility of mouse trophoblasts to natural killer cell-mediated attack in vivo

artículo científico publicado en 2002

It's a Good Year for Blimp-1 (and Plasma Cells)

artículo científico publicado el 1 de octubre de 2003

Laurie Glimcher: merging cell biology and immune function. Interview by Sedwick Caitlin

artículo científico publicado en 2010

Lentivirus delivery of shRNA constructs into osteoblasts

artículo científico publicado en 2008

Lineage commitment in lymphocytes: controlling the immune response

artículo científico publicado el 1 de octubre de 2001

Lineage commitment in the immune system: the T helper lymphocyte grows up.

artículo científico publicado en 2000

Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis

artículo científico publicado en 2004

Loss of a DNA-protein complex correlates with extinguished major histocompatibility complex class II expression in a human B cell

artículo científico publicado en 1990

MEKK2 mediates an alternative β-catenin pathway that promotes bone formation

artículo científico publicado en 2016

MHC class II, antigen presentation and tumor necrosis factor in renal tubular epithelial cells

artículo científico publicado en 1990

MLK3 regulates bone development downstream of the faciogenital dysplasia protein FGD1 in mice

artículo científico publicado en 2011

Magnitude of response of histocompatibility-restricted T-cell clones is a function of the product of the concentrations of antigen and Ia molecules

artículo científico publicado el 1 de octubre de 1983

Maintenance of mouse trophoblast stem cell proliferation by TGF-beta/activin

artículo científico publicado en 2004

Major histocompatibility complex class II+B7-1+ tumor cells are potent vaccines for stimulating tumor rejection in tumor-bearing mice

artículo científico publicado en 1995

Marking IL-4-producing cells by knock-in of the IL-4 gene

scientific article published on 01 February 1999

Mice lacking major histocompatibility complex class I and class II molecules

artículo científico publicado en 1993

Mitogen-activated protein kinase pathways in osteoblasts

artículo científico

Molecular Pathways: Immunosuppressive Roles of IRE1α-XBP1 Signaling in Dendritic Cells of the Tumor Microenvironment

artículo científico publicado en 2016

Molecular cloning of mouse cathepsin D.

artículo científico publicado en 1990

Molecular mechanisms regulating Th1 immune responses

artículo científico publicado en 2001

Most gamma delta T cells develop normally in the absence of MHC class II molecules

artículo científico publicado en 1993

Mouse ATF-2 null mutants display features of a severe type of meconium aspiration syndrome

scientific article published on 01 June 1999

Murine class II (Ia) molecules associate with human invariant chain

scientific article published on 01 March 1987

Murine syngeneic mixed lymphocyte response. I. Target antigens are self Ia molecules

artículo científico publicado el 1 de noviembre de 1981

Mutations of class II MHC molecules

artículo científico publicado en 1987

Mycobacterium tuberculosis Rv2224c modulates innate immune responses

scientific journal article

NF-AT-Driven interleukin-4 transcription potentiated by NIP45

artículo científico publicado en 1996

NFATc1 and NFATc2 repress spontaneous osteoarthritis

artículo científico publicado en 2013

NFATc1 and NFATc2 together control both T and B cell activation and differentiation

artículo científico publicado en 2001

NFATc1 balances quiescence and proliferation of skin stem cells

scientific journal article

NFATc1 in inflammatory and musculoskeletal conditions

artículo científico publicado en 2010

NFATc1 in mice represses osteoprotegerin during osteoclastogenesis and dissociates systemic osteopenia from inflammation in cherubism

artículo científico publicado en 2008

NFATc2 and NFATc3 regulate TH2 differentiation and modulate TCR-responsiveness of naïve TH cells

artículo científico publicado el 10 de diciembre de 2001

NIP45 controls the magnitude of the type 2 T helper cell response.

artículo científico publicado en 2010

Nod/Ripk2 signaling in dendritic cells activates IL-17A-secreting innate lymphoid cells and drives colitis in T-bet-/-.Rag2-/- (TRUC) mice.

artículo científico publicado en 2014

Non-consensus DNA sequences function in a cell-type-specific enhancer of the mouse class II MHC gene A alpha

artículo científico publicado en 1991

Novel NFAT sites that mediate activation of the interleukin-2 promoter in response to T-cell receptor stimulation

artículo científico publicado en 1995

Novel roles for XBP1 in hematopoietic development

artículo científico publicado en 2016

Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer

artículo científico publicado en 2010

Osteoimmunology at the nexus of arthritis, osteoporosis, cancer, and infection

artículo científico publicado el 1 de julio de 2011

Osteopontin expression is essential for interferon-alpha production by plasmacytoid dendritic cells.

artículo científico publicado en 2006

Ovarian insufficiency and early pregnancy loss induced by activation of the innate immune system

artículo científico publicado en 2004

Peripheral lymphoid development and function in TCR mutant mice

artículo científico publicado en 1994

Pharmacologic targeting of a stem/progenitor population in vivo is associated with enhanced bone regeneration in mice

artículo científico publicado en 2008

Pillars article: A novel transcription factor, T-bet, directs Th1 lineage commitment. Cell. 2000. 100: 655-669.

artículo científico publicado en 2015

Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1

scientific journal article

Plasma cell differentiation requires the transcription factor XBP-1

artículo científico publicado en 2001

Polyclonal B-cell activation by a B-cell differentiation factor B151-TRF2. IV. B151-TRF2-responsive F1 B cells consist of two separate populations capable of recognizing only one of the parental I-A products expressed on B cells

artículo científico publicado en 1987

Post-translational control of T cell development by the ESCRT protein CHMP5.

artículo científico publicado en 2017

Prevention of nephritis in major histocompatibility complex class II-deficient MRL-lpr mice

artículo científico publicado en 1994

Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1alpha

artículo científico publicado en 2006

Production of autoreactive I region-restricted T cell hybridomas

artículo científico publicado el 1 de agosto de 1982

Promoter accessibility within the environment of the MHC is affected in class II-deficient combined immunodeficiency.

artículo científico publicado en 1993

Prostaglandin E2 inhibits the activation of cloned T cell hybridomas

artículo científico publicado en 1985

Proteasome inhibitors disrupt the unfolded protein response in myeloma cells

artículo científico publicado en 2003

Protective role of major histocompatibility complex class II Ebd transgene on collagen-induced arthritis

artículo científico publicado en 1994

Protective role of nuclear factor of activated T cells 2 in CD8+ long-lived memory T cells in an allergy model

artículo científico publicado en 2008

Protein folding stress in neurodegenerative diseases: a glimpse into the ER

artículo científico publicado el 31 de enero de 2011

Protein homeostasis networks in physiology and disease

artículo científico publicado el 1 de abril de 2011

RETRACTED: The unfolded protein response element IRE1α senses bacterial proteins invading the ER to activate RIG-I and innate immune signaling

retracted scientific article published on May 2013

Rapid turnover of unspliced Xbp-1 as a factor that modulates the unfolded protein response

scientific journal article

Recent developments in the transcriptional regulation of cytolytic effector cells

artículo científico publicado en 2004

Reflections on health care

artículo científico publicado en 2009

Regulation of MHC class II gene transcription

artículo científico publicado en 1991

Regulation of Memory Formation by the Transcription Factor XBP1.

artículo científico publicado en 2016

Regulation of T cell receptor expression in immature CD4+CD8+ thymocytes by p56lck tyrosine kinase: basis for differential signaling by CD4 and CD8 in immature thymocytes expressing both coreceptor molecules

artículo científico publicado en 1993

Regulation of adult bone mass by the zinc finger adapter protein Schnurri-3.

artículo científico publicado en 2006

Regulation of bone formation and immune cell development by Schnurri proteins

artículo científico publicado en 2010

Regulation of class II gene expression in a murine pre-B cell line.

artículo científico publicado en 1986

Regulation of class II gene expression: analysis in B cell stimulatory factor 1-inducible murine pre-B cell lines

scientific article published on 01 November 1986

Regulation of cytokine gene expression in T helper cell subsets.

artículo científico publicado en 1994

Regulation of hepatic lipogenesis by the transcription factor XBP1

scientific journal article

Regulation of innate immunity by signaling pathways emerging from the endoplasmic reticulum

artículo científico publicado el 18 de noviembre de 2010

Regulation of the E beta gene in vivo: lessons from E beta d transgenic mice

artículo científico publicado en 1996

Rejection of MHC class II-transfected tumor cells requires induction of tumor-encoded B7-1 and/or B7-2 costimulatory molecules

artículo científico publicado en 1996

Renal tubular cell expression of MHC class II (I-Eb) is insufficient to initiate immune injury in a transgenic kidney transplant model.

artículo científico publicado en 1993

Repression of Constitutive and Interferon-gamma-Induced Class II Major Histocompatibility Complex Genes by Cyclic AMP and Prostaglandins

artículo científico publicado en 1995

Repression of class II major histocompatibility complex genes by cyclic AMP is mediated by conserved promoter elements

artículo científico publicado en 1991

Requirement for the c-Maf transcription factor in crystallin gene regulation and lens development

artículo científico publicado en 1999

Restoration of T-box-containing protein expressed in T cells protects against allergen-induced asthma.

artículo científico publicado en 2008

Retraction Notice to: The Unfolded Protein Response Element IRE1α Senses Bacterial Proteins Invading the ER to Activate RIG-I and Innate Immune Signaling.

artículo científico publicado en 2018

Role of lipopolysaccharide and IL-4 in control of transcription of the class II A alpha gene

artículo científico publicado en 1991

SMURF2 regulates bone homeostasis by disrupting SMAD3 interaction with vitamin D receptor in osteoblasts

artículo científico publicado en 2017

Schnurri-3 (KRC) interacts with c-Jun to regulate the IL-2 gene in T cells

artículo científico publicado en 2004

Schnurri-3 is an essential regulator of osteoblast function and adult bone mass

artículo científico publicado en 2007

Schnurri-3 regulates ERK downstream of WNT signaling in osteoblasts

artículo científico publicado en 2013

Schnurri-3: A Key Regulator of Postnatal Skeletal Remodeling

artículo científico publicado en 2007

Self-reactive T cells selected on thymic cortical epithelium are polyclonal and are pathogenic in vivo

artículo científico publicado en 1999

Sequences and factors: a guide to MHC class-II transcription

artículo científico publicado el 1 de enero de 1992

Sequential involvement of NFAT and Egr transcription factors in FasL regulation

scientific journal article

Serologic and functional characterization of a panel of antigen-presenting cell lines expressing mutant I-A class II molecules

artículo científico publicado el 1 de noviembre de 1983

Severity of innate immune-mediated colitis is controlled by the cytokine deficiency-induced colitis susceptibility-1 (Cdcs1) locus

artículo científico publicado en 2011

Signaling pathways in Th2 development

artículo científico publicado en 2004

Signalling through the MHC class II cytoplasmic domain is required for antigen presentation and induces B7 expression

artículo científico publicado el 19 de noviembre de 1992

Silencing of lipid metabolism genes through IRE1α-mediated mRNA decay lowers plasma lipids in mice.

artículo científico publicado en 2012

Single amino acid mutations in the murine MHC class II A beta cytoplasmic domain abrogate antigen presentation

artículo científico publicado el 15 de diciembre de 1997

Spontaneous development of inflammatory bowel disease in T cell receptor mutant mice

scientific article published on 01 October 1993

Stimulated kidney tubular epithelial cells express membrane associated and secreted TNF alpha

artículo científico publicado en 1991

Structural mutation affecting intracellular transport and cell surface expression of murine class II molecules

artículo científico publicado en 1988

Structure and function of murine class II major histocompatibility complex genes.

artículo científico publicado en 1986

Sustained T-bet expression confers polarized human TH2 cells with TH1-like cytokine production and migratory capacities

artículo científico publicado en 2004

Sustained T-bet expression confers polarized human TH2 cells with TH1-like cytokine production and migratory capacities☆

article

T cell abnormalities in NZB mice occur independently of autoantibody production

artículo científico publicado en 1981

T cell clones and hybridomas as probes for the analysis of the syngeneic mixed leukocyte reaction

artículo científico publicado el 1 de mayo de 1983

T cell directives for transcriptional regulation in asthma

artículo científico publicado en 2003

T cell receptor gene segment usage in a panel of hen-egg white lysozyme specific, I-Ak-restricted T helper hybridomas

artículo científico publicado en 1989

T helper cell fate specified by kinase-mediated interaction of T-bet with GATA-3.

artículo científico publicado en 2005

T(H) cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes

artículo científico publicado en 2002

T-Bet expression and failure of GATA-3 cross-regulation lead to default production of IFN-gamma by gammadelta T cells

artículo científico publicado en 2002

T-bet Runs INTERFERence

artículo científico publicado en 2017

T-bet controls autoaggressive CD8 lymphocyte responses in type 1 diabetes

artículo científico publicado en 2004

T-bet controls pathogenicity of CTLs in the heart by separable effects on migration and effector activity

artículo científico publicado en 2006

T-bet deficiency reduces atherosclerosis and alters plaque antigen-specific immune responses

artículo científico publicado en 2005

T-bet in disease.

artículo científico publicado en 2011

T-bet is required for optimal production of IFN-gamma and antigen-specific T cell activation by dendritic cells

artículo científico publicado en 2003

T-bet is required for optimal proinflammatory CD4+ T-cell trafficking.

artículo científico publicado en 2005

T-bet plays a key role in NK-mediated control of melanoma metastatic disease

artículo científico publicado en 2008

T-bet polymorphisms are associated with asthma and airway hyperresponsiveness

artículo científico publicado en 2006

T-bet regulates IgG class switching and pathogenic autoantibody production

scientific journal article

T-bet regulates metastasis rate in a murine model of primary prostate cancer

artículo científico publicado en 2004

T-bet regulates the terminal maturation and homeostasis of NK and Valpha14i NKT cells

artículo científico publicado en 2004

T-bet represses T(H)17 differentiation by preventing Runx1-mediated activation of the gene encoding RORγt

scientific journal article

T-bet, a T cell-associated transcription factor, is expressed in Hodgkin's lymphoma

artículo científico publicado en 2005

T-bet, a T-cell-associated transcription factor, is expressed in a subset of B-cell lymphoproliferative disorders

artículo científico publicado en 2004

T-bet, a Th1 transcription factor regulates the expression of Tim-3.

artículo científico publicado en 2010

T-bet-/- RAG2-/- ulcerative colitis: the role of T-bet as a peacekeeper of host-commensal relationships

scientific article published on 08 August 2009

T-bet-deficient NOD mice are protected from diabetes due to defects in both T cell and innate immune system function

scientific article published on 17 June 2009

T-bet-dependent expression of osteopontin contributes to T cell polarization

artículo científico publicado en 2005

T-bet: a bridge between innate and adaptive immunity.

artículo científico publicado en 2013

T-cell sets that control B-cell secretion of antigen-specific immunoglobulin also control secretion of nonspecific immunoglobulin

scientific article published on 01 July 1982

TAK1 is an essential regulator of BMP signalling in cartilage

scientific journal article

TAK1 mediates BMP signaling in cartilage

artículo científico publicado en 2010

TBX21: a functional variant predicts improvement in asthma with the use of inhaled corticosteroids

artículo científico publicado en 2004

TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages.

artículo científico publicado en 2010

TNF-alpha is expressed on the surface of kidney proximal tubular cells

artículo científico publicado en 1991

Targeting Tim-1 to overcome resistance to transplantation tolerance mediated by CD8 T17 cells.

scholarly article

Targeting abnormal ER stress responses in tumors: A new approach to cancer immunotherapy

artículo científico publicado en 2016

Targeting skeletal endothelium to ameliorate bone loss

artículo científico publicado en 2018

Targeting the UPR transcription factor XBP1 protects against Huntington's disease through the regulation of FoxO1 and autophagy

artículo científico publicado en 2012

Tetraspanin CD9 and ectonucleotidase CD73 identify an osteochondroprogenitor population with elevated osteogenic properties

artículo científico publicado en 2015

The E3 ubiquitin ligase Wwp2 regulates craniofacial development through mono-ubiquitylation of Goosecoid

artículo científico publicado en 2010

The IRE1 endoplasmic reticulum stress sensor activates natural killer cell immunity in part by regulating c-Myc

scientific article published on 13 May 2019

The NOD mouse: recessive diabetogenic gene in the major histocompatibility complex

artículo científico publicado en 1986

The Transcription Factor NFAT4 Is Involved in the Generation and Survival of T Cells

artículo científico publicado el 1 de septiembre de 1998

The X-box binding protein-1 transcription factor is required for plasma cell differentiation and the unfolded protein response

artículo científico publicado en 2003

The adjuvant activity of CpG DNA requires T-bet expression in dendritic cells

artículo científico publicado en 2005

The autologous mixed lymphocyte reaction in strains of mice with autoimmune disease

artículo científico publicado en 1980

The basic domain/leucine zipper protein hXBP-1 preferentially binds to and transactivates CRE-like sequences containing an ACGT core

artículo científico publicado en 1996

The biologic significance of alloreactivity. The ontogeny of T-cell sets specific for alloantigens or modified self antigens

artículo científico publicado el 1 de noviembre de 1978

The daily job of night killers: alternative roles of the BCL-2 family in organelle physiology

artículo científico publicado en 2008

The endoplasmic reticulum stress response in immunity and autoimmunity

artículo científico publicado en 2008

The gene encoding early growth response 2, a target of the transcription factor NFAT, is required for the development and maturation of natural killer T cells

scientific article published on 25 January 2009

The isolation and functional characterization of autoimmune clones expressing inappropriate Ia

scientific article published on 01 August 1984

The microtubule-associated protein DCAMKL1 regulates osteoblast function via repression of Runx2

artículo científico publicado en 2013

The nuclear factor of activated T cells (NFAT) transcription factor NFATp (NFATc2) is a repressor of chondrogenesis

artículo científico publicado en 2000

The p38 MAPK pathway is essential for skeletogenesis and bone homeostasis in mice

artículo científico publicado en 2010

The presence of a DNA binding complex correlates with E beta class II MHC gene expression

artículo científico publicado en 1990

The proapoptotic BCL-2 family member BIM mediates motoneuron loss in a model of amyotrophic lateral sclerosis

scientific article published on 18 May 2007

The proto-oncogene c-maf is responsible for tissue-specific expression of interleukin-4.

artículo científico publicado en 1996

The proximal promoter of the IL-4 gene is composed of multiple essential regulatory sites that bind at least two distinct factors

artículo científico publicado en 1995

The regulatory gene, hXBP-1, and its target, HLA-DRA, utilize both common and distinct regulatory elements and protein complexes

artículo científico publicado en 1993

The ripple effect: why promoting female leadership in global health matters.

artículo científico publicado en 2016

The role of "indirect" recognition in initiating rejection of skin grafts from major histocompatibility complex class II-deficient mice

artículo científico publicado en 1993

The role of Th1/Th2 polarization in mucosal immunity

artículo científico publicado en 2002

The specificity of the syngeneic mixed leukocyte response, a primary anti-I region T cell proliferative response, is determined intrathymically

scientific article published on 01 September 1982

The structure-function relationship of I-A molecules: correlation of serologic and functional phenotypes of four I-Ak mutant cell lines

artículo científico publicado el 1 de diciembre de 1984

The transcription T-bet is required for optimal proinflammatory trafficking of CD4+ T cells.

artículo científico publicado en 2005

The transcription factor NF-ATc is essential for cardiac valve formation

artículo científico publicado el 12 de marzo de 1998

The transcription factor T-bet regulates mucosal T cell activation in experimental colitis and Crohn's disease

artículo científico publicado en 2002

The transcription factor XBP-1 is essential for the development and survival of dendritic cells

scientific journal article

The transcription factor XBP1 is selectively required for eosinophil differentiation

artículo científico publicado en 2015

The transcription factor c-Maf controls the production of interleukin-4 but not other Th2 cytokines

scientific journal article

The transcription factor cyclic AMP-responsive element-binding protein H regulates triglyceride metabolism

artículo científico publicado en 2011

The transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genes

artículo científico publicado en 2009

The unfolded protein response: integrating stress signals through the stress sensor IRE1α

artículo científico publicado en 2011

Three distinct signals can induce class II gene expression in a murine pre-B-cell line

artículo científico publicado en 1986

Three in vivo promoter phenotypes in MHC class II deficient combined immunodeficiency

artículo científico publicado en 1993

Thymic stromal cell specialization and the T-cell receptor repertoire

artículo científico publicado en 1997

Thymocyte development in major histocompatibility complex-deficient mice: evidence for stochastic commitment to the CD4 and CD8 lineages

artículo científico publicado en 1993

Tissue-specific regulation of cytokine gene expression

artículo científico publicado en 1999

Transcription factor B cell lineage-specific activator protein regulates the gene for human X-box binding protein 1

artículo científico publicado en 1996

Transcription factor T-bet regulates inflammatory arthritis through its function in dendritic cells

artículo científico publicado en 2006

Transcription factor T-bet regulates skin sclerosis through its function in innate immunity and via IL-13

artículo científico publicado en 2007

Transcription factors in lymphocyte development--T and B cells get together

artículo científico publicado en 1999

Transcription of the interleukin 4 gene is regulated by multiple promoter elements

artículo científico publicado en 1993

Transcription: tantalizing times for T cells

artículo científico publicado en 2002

Transcriptional regulation of Th1/Th2 polarization

artículo científico publicado en 2000

Transforming growth factor beta 1 repression of the HLA-DR alpha gene is mediated by conserved proximal promoter elements.

artículo científico publicado en 1993

Transgenic mice expressing MHC class II molecules with truncated A beta cytoplasmic domains reveal signaling-independent defects in antigen presentation

artículo científico publicado en 1995

Transgenic tubular cell expression of class II is insufficient to initiate immune renal injury

artículo científico publicado en 1993

Translating Research into Therapies

artículo científico publicado el 16 de marzo de 2012

Trawling for treasure: tales of T-bet

artículo científico publicado en 2007

Truncation of the class II beta-chain cytoplasmic domain influences the level of class II/invariant chain-derived peptide complexes

artículo científico publicado en 1996

Trypanosoma cruzi infection in MHC-deficient mice: further evidence for the role of both class I- and class II-restricted T cells in immune resistance and disease

Tumor cells expressing major histocompatibility complex class II and B7 activation molecules stimulate potent tumor-specific immunity

scientific article published on 01 October 1993

Tumor necrosis factor receptor-associated factor (TRAF)2 represses the T helper cell type 2 response through interaction with NFAT-interacting protein (NIP45).

artículo científico publicado en 2001

Tumorigenic and Immunosuppressive Effects of Endoplasmic Reticulum Stress in Cancer

artículo científico publicado en 2017

Turning down the system: counter-regulatory mechanisms in bone and adaptive immunity

artículo científico publicado en 2005

Two levels of help for B cell alloantibody production

artículo científico publicado en 1996

Uncoupling of growth plate maturation and bone formation in mice lacking both Schnurri-2 and Schnurri-3

artículo científico publicado en 2010

Unfolded protein response transcription factor XBP-1 does not influence prion replication or pathogenesis.

artículo científico publicado en 2008

Unopposed positive selection and autoreactivity in mice expressing class II MHC only on thymic cortex

artículo científico publicado en 1996

Upstream elements of the MHC class II E beta gene active in B cells

artículo científico publicado en 1991

Using thymus anatomy to dissect T cell repertoire selection

artículo científico publicado en 1999

Variable effects of transgenic c-Maf on autoimmune diabetes.

artículo científico publicado en 2001

William Erwin Paul (1936-2015).

artículo científico publicado en 2015

XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response

artículo científico publicado el 1 de noviembre de 2003

XBP-1 and the unfolded protein response (UPR)

artículo científico publicado en 2020

XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy

artículo científico publicado en 2009

XBP-1 deficiency in the nervous system reveals a homeostatic switch to activate autophagy

artículo científico publicado en 2009

XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glands

scientific journal article

XBP-1 specifically promotes IgM synthesis and secretion, but is dispensable for degradation of glycoproteins in primary B cells

artículo científico publicado en 2005

XBP1 Controls Maturation of Gastric Zymogenic Cells by Induction of MIST1 and Expansion of the Rough Endoplasmic Reticulum

artículo científico publicado el 14 de octubre de 2010

XBP1 governs late events in plasma cell differentiation and is not required for antigen-specific memory B cell development

scientific article published on 14 September 2009

XBP1 is essential for survival under hypoxic conditions and is required for tumor growth.

artículo científico publicado en 2004

XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease

artículo científico publicado en 2008

XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway

artículo científico publicado en 2014

XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation

artículo científico publicado en 2004

XBP1-Independent UPR Pathways Suppress C/EBP-β Mediated Chondrocyte Differentiation in ER-Stress Related Skeletal Disease

artículo científico publicado en 2015

XBP1: the last two decades

artículo científico publicado en 2010

c-maf promotes T helper cell type 2 (Th2) and attenuates Th1 differentiation by both interleukin 4-dependent and -independent mechanisms

artículo científico publicado en 1998

mXBP/CRE-BP2 and c-Jun form a complex which binds to the cyclic AMP, but not to the 12-O-tetradecanoylphorbol-13-acetate, response element

artículo científico publicado en 1990

p38α MAPK is required for tooth morphogenesis and enamel secretion

artículo científico publicado en 2014